NVN Liquidation (NOVNQ) 8-K Entry into a Material Definitive Agreement

Exhibit 23.1

Consent of Independent Auditor

Novan, Inc.

Durham, North Carolina

We consent to the incorporation by reference in the Registration Statements on Form S-1 (No. 333-233632), Form S-3 (No. 333-262865) and Form S-8 (No. 333-213854, No. 333-219913, No. 333-233630, No. 333-233631, and No. 333-258743) of Novan, Inc. of our reports dated March 2, 2022 and March 3, 2022, relating to the financial statements of EPI Health, LLC as of and for the years ended September 30, 2021 and 2020, and as of and for the three months ended December 31, 2021 and 2020, respectively, appearing in this Current Report on Form 8-K of Novan, Inc.

/s/ Elliott Davis, LLC

Charleston, South Carolina

March 11, 2022