Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the reference to our firm under the caption “Experts” in this Registration Statement (Form S-3) and related Prospectus of Immunome, Inc. for the registration of 2,175,489 shares of its common stock and to the incorporation by reference therein of our report dated March 28, 2024, with respect to the consolidated financial statements of Immunome, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2023, filed with the Securities and Exchange Commission.
/s/ Ernst & Young LLP
Philadelphia, Pennsylvania
April 3, 2024
