| | (a) and (b) | | Amount beneficially owned: As of December 31, 2021, the Reporting Person beneficially owned 1,858,462 shares of the Issuer’s Common Stock, representing approximately 6.4% of the outstanding Common Stock, consisting of (a) 786,483 shares of Common Stock held directly by Dr. Nichtberger, representing approximately 2.8% of the outstanding Common Stock, (b) 363,000 shares of Common Stock held directly by the 2017 Nichtberger Family Trust, representing approximately 1.3% of the outstanding Common Stock, and (c) 708,979 shares of Common Stock underlying options held directly by Dr. Nichtberger that are exercisable within 60 days of December 31, 2021, representing approximately 2.4% of the outstanding Common Stock. Dr. Nichtberger is a trustee of the 2017 Nichtberger Family Trust. The foregoing percentages were calculated based on the 28,331,638 shares of the Issuer’s Common Stock outstanding as of October 29, 2021 as reported in the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on November 1, 2021. |
| | (c) | | Numberof shares as to which such person has: (i) Sole power to vote or to direct the vote: 1,858,462 (ii) Shared power to vote or to direct the vote: 0 (iii) Sole power to dispose or to direct the disposition of: 1,858,462 (iv) Shared power to dispose or to direct the disposition of: 0 |