Horizon Therapeutics Public (HZNP) S-8 Registration of securities for employees

Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in this Registration Statement on Form S-8 of our report dated March 18, 2013 relating to the financial statements and the effectiveness of internal control over financial reporting, which appears in Horizon Pharma Inc.‘s Annual Report on Form10-K for the year ended December 31, 2012.

/s/ PricewaterhouseCoopers LLP

Chicago, Illinois

November 13, 2013