Organovo (ONVO) 10-Q 9 Nov 17 2018 Q2 Quarterly report Financial data

Document and Entity Information

Document and Entity Information - shares	6 Months Ended
	Sep. 30, 2017	Nov. 01, 2017
Document And Entity Information [Abstract]
Document Type	10-Q
Amendment Flag	false
Document Period End Date	Sep. 30, 2017
Document Fiscal Year Focus	2,018
Document Fiscal Period Focus	Q2
Trading Symbol	ONVO
Entity Registrant Name	ORGANOVO HOLDINGS, INC.
Entity Central Index Key	1,497,253
Current Fiscal Year End Date	--03-31
Entity Filer Category	Accelerated Filer
Entity Common Stock, Shares Outstanding		106,923,570

Condensed Consolidated Balance

Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2017	Mar. 31, 2017
Current Assets
Cash and cash equivalents	$ 50,732	$ 62,751
Accounts receivable	1,033	647
Grant receivable	149	0
Inventory, net	496	550
Prepaid expenses and other current assets	934	1,144
Total current assets	53,344	65,092
Fixed assets, net	3,255	3,840
Restricted cash	127	127
Other assets, net	185	121
Total assets	56,911	69,180
Current Liabilities
Accounts payable	477	1,171
Accrued expenses	2,821	4,101
Deferred revenue	654	582
Deferred rent	173	157
Total current liabilities	4,125	6,011
Deferred revenue, net of current portion	67	58
Deferred rent, net of current portion	661	749
Total liabilities	4,853	6,818
Commitments and Contingencies (Note 4)	0	0
Stockholders’ Equity
Common stock, $0.001 par value; 150,000,000 shares authorized, 106,904,525 and 104,551,466 shares issued and outstanding at September 30, 2017 and March 31, 2017, respectively	107	104
Additional paid-in capital	270,842	261,586
Accumulated deficit	(218,880)	(199,317)
Accumulated other comprehensive income (loss)	(11)	(11)
Total stockholders’ equity	52,058	62,362
Total Liabilities and Stockholders’ Equity	$ 56,911	$ 69,180

Condensed Consolidated Balance3

Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares	Sep. 30, 2017	Mar. 31, 2017
Statement Of Financial Position [Abstract]
Common stock, par value	$ 0.001	$ 0.001
Common stock, shares authorized	150,000,000	150,000,000
Common stock, shares issued	106,904,525	104,551,466
Common stock, shares outstanding	106,904,525	104,551,466

Unaudited Condensed Consolidate

Unaudited Condensed Consolidated Statements of Operations and Other Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Revenues
Products and services	$ 946	$ 1,023	$ 1,890	$ 1,697
Collaborations and licenses	260	345	306	557
Grants	149	8	149	12
Total Revenues	1,355	1,376	2,345	2,266
Cost of revenues	254	393	555	561
Research and development expenses	4,944	4,544	9,977	8,987
Selling, general, and administrative expenses	5,736	5,918	11,592	10,974
Total costs and expenses	10,934	10,855	22,124	20,522
Loss from Operations	(9,579)	(9,479)	(19,779)	(18,256)
Other Income (Expense)
Change in fair value of warrant liabilities	0	0	0	(5)
Interest income	118	37	216	74
Total Other Income (Expense)	118	37	216	69
Income Tax Expense	0	0	0	(22)
Net Loss	(9,461)	(9,442)	(19,563)	(18,209)
Currency Translation Adjustment	0	(7)	(11)	(7)
Comprehensive Loss	$ (9,461)	$ (9,449)	$ (19,574)	$ (18,216)
Net loss per common share—basic and diluted	$ (0.09)	$ (0.10)	$ (0.19)	$ (0.20)
Weighted average shares used in computing net loss per common share—basic and diluted	106,297,699	93,185,400	105,497,939	92,790,850

Unaudited Condensed Consolidat5

Unaudited Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Sep. 30, 2017	Sep. 30, 2016
Cash Flows From Operating Activities
Net loss	$ (19,563)	$ (18,209)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	647	502
Change in fair value of warrant liabilities	0	5
Stock-based compensation	4,350	3,522
Increase (decrease) in cash resulting from changes in:
Accounts receivable	(386)	(347)
Grants receivable	(149)	0
Inventory	54	(111)
Prepaid expenses and other assets	210	80
Accounts payable	(694)	(33)
Accrued expenses	(1,280)	381
Deferred rent	(72)	(68)
Deferred revenue	81	(631)
Net cash used in operating activities	(16,802)	(14,909)
Cash Flows From Investing Activities
Purchases of fixed assets	(56)	(452)
Purchases of intangible assets	(70)	0
Net cash used in investing activities	(126)	(452)
Cash Flows From Financing Activities
Proceeds from issuance of common stock and exercise of warrants, net	4,084	4,500
Proceeds from exercise of stock options	825	500
Net cash provided by financing activities	4,909	5,000
Effect of currency exchange rate changes on cash and cash equivalents	0	(7)
Net (Decrease) in Cash and Cash Equivalents	(12,019)	(10,368)
Cash and Cash Equivalents at Beginning of Period	62,751	62,091
Cash and Cash Equivalents at End of Period	50,732	51,723
Supplemental Disclosure of Cash Flow Information:
Interest paid	0	0
Income taxes paid	$ 0	$ 22

Description of Business and Sum

Description of Business and Summary of Significant Accounting Policies	6 Months Ended
	Sep. 30, 2017
Accounting Policies [Abstract]
Description of Business and Summary of Significant Accounting Policies	Note Nature of operations and basis of presentation References in these notes to the unaudited condensed consolidated financial statements to “Organovo Holdings, Inc.,” “Organovo Holdings,” “we,” “us,” “our,” “the Company” and “our Company” refer to Organovo Holdings, Inc. and its consolidated subsidiaries. Our consolidated financial statements include the accounts of the Company as well as its wholly-owned subsidiaries, with all material intercompany accounts and transactions eliminated in consolidation. In December 2014, we established a wholly-owned subsidiary, Samsara Sciences, Inc., to focus on the acquisition of qualified cells in support of our commercial and research endeavors. In September 2015, we established another wholly-owned subsidiary in the United Kingdom, Organovo U.K., Ltd., for the primary purpose of establishing a sales presence in Europe. Since its inception, the Company has devoted its efforts primarily to developing and commercializing a platform technology and functional human tissues that can be employed in drug discovery and development, biological research, and as therapeutic implants for the treatment of damaged or degenerating tissues and organs. The Company has also focused efforts on raising capital and building infrastructure. In November 2014, the Company announced the commercial release of its first product, the ExVive™ Human Liver Tissue for use in toxicology and other drug testing. In September 2016, the Company announced that it had begun commercial contracting for services relating to its second product, the ExVive™ Human Kidney tissue. The Company’s activities are subject to significant risks and uncertainties including failing to successfully develop products and services based on its technology and to achieve the market acceptance necessary to generate sufficient revenues to support its operations and to achieve and sustain profitability. The accompanying interim condensed consolidated financial statements have been prepared by the Company, without audit, in accordance with the instructions to Form 10-Q and, therefore, do not necessarily include all information and footnotes necessary for a fair statement of its financial position, results of operations, stockholders’ equity and cash flows in accordance with generally accepted accounting principles (“GAAP”). The balance sheet at March 31, 2017 is derived from the Company’s audited balance sheet at that date. In the opinion of management, the unaudited financial information for the interim periods presented reflects all adjustments, which are only normal and recurring, necessary for a fair statement of the Company’s financial position, results of operations, stockholders’ equity and cash flows. These financial statements should be read in conjunction with the financial statements included in the Company’s Annual Report on Form 10-K for the year ended March 31, 2017, filed with the Securities and Exchange Commission (the “SEC”) on June 7, 2017. Operating results for interim periods are not necessarily indicative of operating results for the Company’s fiscal year ending March 31, 2018. Liquidity As of September 30, 2017, the Company had cash and cash equivalents of approximately $50.7 million and an accumulated deficit of approximately $218.9 million. The Company also had negative cash flows from operations of approximately $16.8 million during the six months ended September 30, 2017. Through September 30, 2017, the Company has financed its operations primarily through the sale of convertible notes, the private placement of equity securities, the sale of common stock through public and at-the-market (“ATM”) offerings, and through revenue derived from product and research service-based agreements, collaborative research agreements, grants, and licenses. During the six months ended September 30, 2017, the Company issued 1,538,217 shares of its common stock through its ATM facility and received net proceeds of approximately $4.0 million. On October 25, 2016, the Company closed the issuance and sale of 10,065,000 shares of its common stock in an underwritten public offering. The Company received net proceeds of approximately $25.7 million in the offering, after deducting underwriting discounts and commissions and the Company’s expenses. Based on its current operating plan and available cash resources, the Company has sufficient resources to fund its business for at least the next twelve months from the financial statement issuance date. The Company will need additional capital to further fund the development and commercialization of its human tissues that can be employed in drug discovery and development, biological research, and as therapeutic implants for the treatment of damaged or diseased tissues and organs. The Company intends to cover its future operating expenses through cash on hand, through revenue derived from research service agreements, product sales, collaborative research agreements, grants and royalty payments, and through the issuance of additional equity or debt securities. Depending on market conditions, we cannot be sure that additional financing will be available when needed or that, if available, financing will be obtained on terms favorable to us or to our stockholders. Having insufficient funds may require us to delay, scale back, or eliminate some or all of our development programs or relinquish rights to our technology on less favorable terms than we would otherwise choose. Failure to obtain adequate financing could eventually adversely affect our ability to operate as a going concern. If we raise additional funds from the issuance of equity securities, substantial dilution to our existing stockholders would likely result. If we raise additional funds by incurring debt financing, the terms of the debt may involve significant cash payment obligations as well as covenants and specific financial ratios that may restrict our ability to operate our business. Use of estimates The preparation of the financial statements in conformity with accounting principles generally accepted in the United States requires management to make estimates and assumptions that affect certain reported amounts and disclosures. Accordingly, actual results could differ from those estimates. Significant estimates used in preparing the condensed consolidated financial statements include those assumed in revenue recognized under the proportional performance model, the valuation of stock-based compensation expense, and the valuation allowance on deferred tax assets. Fair value measurement The Company had issued warrants, of which some were classified as derivative liabilities as a result of the terms in the warrants that provide for down-round protection in the event of a dilutive issuance. The Company used Level 3 inputs (unobservable inputs that are supported by little or no market activity, and that are significant to the fair value of the assets or liabilities) for its valuation methodology for the warrant derivative liabilities. The estimated fair values were determined using a Monte Carlo option pricing model based on various assumptions. The Company’s derivative liabilities were adjusted to reflect estimated fair value at each period end, with any increase or decrease in the estimated fair value being recorded in other income or expense accordingly, as adjustments to the fair value of the derivative liabilities. Various factors are considered in the pricing models the Company used to value the warrants, including the Company’s current stock price, the remaining life of the warrant, the volatility of the Company’s stock price, and the risk-free interest rate. The remaining warrants expired as of March 31, 2017 and were removed from the Balance Sheet. The Company does not have any financial assets or liabilities measured on a fair value basis as of September 30, 2017 or March 31, 2017. Revenue recognition The Company’s revenues are derived from research service agreements, product sales, and collaborative research agreements with pharmaceutical and biotechnology companies, as well as grants and license-payments from the National Institutes of Health (“NIH”), U.S. Treasury Department, academic institutions, and private not-for-profit organizations. The Company recognizes revenue when the following criteria have been met: (i) persuasive evidence of an arrangement exists; (ii) services have been rendered or product has been delivered; (iii) price to the customer is fixed and determinable; and (iv) collection of the underlying receivable is reasonably assured. Billings to customers or payments received from customers are included in deferred revenue on the balance sheet until all revenue recognition criteria are met. As of September 30, 2017 and March 31, 2017, the Company had approximately $721,000 and $640,000, respectively, in deferred revenue related to its grants and royalty payments, collaborative research programs and research service agreements. Revenue arrangements with multiple deliverables The Company follows ASC 605-25 Revenue Recognition – Multiple-Element Arrangements While changes in the allocation of the arrangement consideration between the units of accounting will not affect the amount of total revenue recognized for a particular sales arrangement, any material changes in these allocations could impact the timing of revenue recognition, which could affect the Company’s results of operations. The Company periodically receives license fees for non-exclusive research licensing associated with funded research projects. License fees under these arrangements are recognized over the term of the contract or development period as it has been determined that such licenses do not have stand-alone value. Revenue from research service agreements For research service agreements that contain only a single or primary deliverable, the Company defers any up-front fees collected from customers, and recognizes revenue for the delivered element only when it determines there are no uncertainties regarding customer acceptance. For agreements that contain multiple deliverables, the Company follows ASC 605-25 as described above. Research and development revenue under collaborative agreements The Company’s collaboration revenue consists of license and collaboration agreements that contain multiple elements, which may include non-refundable up-front fees, payments for reimbursement of third-party research costs, payments for ongoing research, payments associated with achieving specific development milestones and royalties based on specified percentages of net product sales, if any. The Company considers a variety of factors in determining the appropriate method of revenue recognition under these arrangements, such as whether the elements are separable, whether there are determinable fair values and whether there is a unique earnings process associated with each element of a contract. The Company recognizes revenue from research funding under collaboration agreements when earned on a “proportional performance” basis as research services are provided or substantive milestones are achieved. We recognize revenue that is contingent upon the achievement of a substantive milestone in its entirety in the period in which the milestone is achieved. A milestone is considered substantive when the consideration payable to us for the milestone (i) is consistent with our performance necessary to achieve the milestone or the increase in value to the collaboration resulting from our performance, (ii) relates solely to our past performance and (iii) is reasonable relative to all of the other deliverables and payments within the arrangement. In making this assessment, we consider all facts and circumstances relevant to the arrangement, including factors such as the risks that must be overcome to achieve the milestone, the level of effort and investment required to achieve the milestone and whether any portion of the milestone consideration is related to future performance or deliverables. The Company initially defers revenue for any amounts billed or payments received in advance of the services being performed, and recognizes revenue pursuant to the related pattern of performance, using the appropriate method of revenue recognition based on its analysis of the related contractual element(s). In November 2014, the Company entered into a collaborative non-exclusive research affiliation with a university medical school and a non-profit medical charity, under which the Company received a one-time grant from the charity towards the placement of a NovoGen Bioprinter at the university for the purpose of developing bioprinted tissues for surgical transplantation research. The Company has recorded $0 and $12,500 for the three months ended September 30, 2017 and 2016 and $0 and $25,000 for the six months ended September 30, 2017 and 2016, respectively, in revenue related to this collaboration in recognition of the proportional performance achieved. In April 2015, the Company entered into a research collaboration agreement with a third party to develop custom tissue models for fixed fees. Based on the proportional performance achieved under this agreement, $150,000 in collaboration revenue was recorded for the three and six months ended September 30, 2017, and $0 collaboration revenue was recorded for the three and six months ended September 30, 2016. Approximately $620,000 in collaboration revenue has been recognized to date under this agreement as of September 30, 2017. Also in April 2015, the Company entered into a multi-year research agreement with a third party to develop multiple custom tissue models for use in drug development. No collaboration revenue was recorded under this agreement during the three and six months ended September 30, 2017. Approximately $332,000 and $533,000 were recorded as revenue in recognition of the proportional performance achieved under this agreement during the three and six months ended September 30, 2016, respectively. In June 2016, the Company announced it had entered into another collaborative non-exclusive research affiliation with a university medical school and a non-profit medical charity, under which the Company received a one-time grant from the charity towards the placement of a NovoGen Bioprinter at the university for the purpose of developing bioprinted tissues for skeletal disease research. The Company received an up-front payment in June 2016, which was initially recorded as deferred revenue. Revenue of $18,000 and $35,000 has been recorded under this agreement during the three and six months ended September 30, 2017, respectively. No revenue was recorded under this agreement as of September 30, 2016. In December 2016, the Company signed another collaborative non-exclusive research affiliation with a university medical school and a non-profit medical charity, under which the Company received a one-time grant from the charity towards the placement of a NovoGen Bioprinter at the university for the purpose of developing an architecturally correct kidney for potential therapeutic applications. The Company received an up-front payment in January and March of 2017, which has been recorded as deferred revenue. Revenue of $9,000 and $19,000 has been recorded under this agreement for the three and six months ended September 30, 2017, respectively. In April 2017, the Company signed a collaborative non-exclusive research affiliation with a university, under which the Company received a one-time non-refundable payment toward the placement of a NovoGen Bioprinter at the university for the purpose of specific research projects mutually agreed by the university and the Company in the field of volumetric muscle loss. The Company received an up-front payment in May of 2017, which has been recorded as deferred revenue. Revenue of approximat ely $14,000 has been recorded under this agreement for the three and six months ended September 30, 2017, beginning subsequent to the installation of the printer in July 2017. In addition, during April 2017, the Company signed a Non-exclusive Patent License agreement with the university including an annual fee of $75,000 for each of the two years for the license to the Company Patents for research use limited to the field of volumetric muscle loss. The Company received the first annual payment of $75,000 in April of 2017, which has been recorded as deferred revenue. Revenue of $18,750 and $37,500 has been recorded under this agreement for the three and six months ended September 30, 2017. In September 2017, the Company entered into an agreement with a company, under which the Company received a one-time non-refundable payment of $50,000 for limited use of a Company Patent in reference to four bioprinters developed and placed at research and academic facilities. The Company has recorded $50,000 for the three months and six months ended September 30, 2017. Product revenue The Company recognizes product revenue at the time of shipment to the customer, provided all other revenue recognition criteria have been met. As our commercial sales increase, we expect to establish a reserve for estimated product returns that will be recorded as a reduction to revenue. This reserve will be maintained to account for future return of products sold in the current period. The reserve will be reviewed quarterly and will be estimated based on an analysis of our historical experience related to product returns. Grant revenue During August 2013, the Company was awarded a research grant by a private, not-for-profit organization for up to $251,700, contingent on go/no-go decisions made by the grantor at the completion of each stage of research as outlined in the grant award. Revenues from the grant are based upon internal costs incurred that are specifically covered by the grant, plus an additional rate that provides funding for overhead expenses. Revenue is recognized when the Company incurs expenses that are related to the grant. Revenue recognized under this grant was approximately $0 and $8,000 for each of the three months ended September 30, 2017 and 2016 and $0 and $12,000 for each of the six months ended September 30, 2017 and 2016, respectively. The Company has completed its obligations under this agreement as of March 31, 2017. During July 2017, the NIH awarded the Company a research grant totaling approximately $1,657,000. The grant provides for fixed payments based on the achievement of certain milestones. Revenue is recognized upon completion of substantive milestones. Revenue recognized under this grant was approximately $149,000 for the three and six months ended September 30 , 2017. Cost of revenues The Company reported $0.3 million and $0.6 million in cost of revenues for the three and six months ended September 30, 2017, respectively. The Company reported $0.4 million and $0.6 million in cost of revenues for the three and six months ended September 30, 2016, respectively. This captures our costs related to manufacturing and delivering our product and service revenue. Net loss per share Basic and diluted net loss per share has been computed using the weighted-average number of shares of common stock outstanding during the period. The weighted-average number of shares used to compute diluted loss per share excludes any assumed exercise of stock options and warrants, shares reserved for purchase under the Company’s 2016 Employee Stock Purchase Plan (“ESPP”), the assumed release of restriction of restricted stock units, and shares subject to repurchase as the effect would be anti-dilutive. No dilutive effect was calculated for the three and six months ended September 30, 2017 or 2016, as the Company reported a net loss for each respective period and the effect would have been anti-dilutive. Common stock equivalents excluded from computing diluted net loss per share were approximately 15.4 million at September 30, 2017, and 13.2 million at September 30, 2016.

Stockholders' Equity

Stockholders' Equity	6 Months Ended
	Sep. 30, 2017
Equity [Abstract]
Stockholders' Equity	Note Stock-based compensation expense and valuation information Stock-based compensation expense for all stock awards consists of the following (in thousands): Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2017 September 30, 2016 September 30, 2017 September 30, 2016 Research and development $ 384 $ 379 $ 715 $ 787 General and administrative $ 1,914 $ 1,714 $ 3,635 $ 2,735 Total $ 2,298 $ 2,093 $ 4,350 $ 3,522 The total unrecognized compensation cost related to unvested stock option grants as of September 30, 2017 was approximately $10,527,000 and the weighted average period over which these grants are expected to vest is 2.43 years. The total unrecognized compensation cost related to unvested restricted stock units (not including performance-based restricted stock units) as of September 30, 2017 was approximately $7,027,000, which will be recognized over a weighted average period of 3.18 years. The total unrecognized compensation cost related to unvested performance-based restricted stock units as of September 30, 2017 was approximately $378,000 which will be recognized over a weighted average period of 2.16 years. As of September 30, 2017, there was no unrecognized stock-based compensation expense for restricted stock awards. The total unrecognized stock-based compensation cost related to unvested ESPP shares as of September 30, 2017 was approximately $25,000, which will be recognized over a period of 5 months. The Company calculates the grant date fair value of all stock-based awards in determining the stock-based compensation expense. Stock-based awards include (i) stock options, (ii) restricted stock awards, (iii) restricted stock units, and (iv) rights to purchase stock under the 2016 Employee Stock Purchase Plan. The Company uses the Black-Scholes valuation model to calculate the fair value of stock options. Stock-based compensation expense is recognized over the vesting period using the straight-line method. The fair value of stock options was estimated at the grant date using the following weighted average assumptions: Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2017 September 30, 2016 September 30, 2017 September 30, 2016 Dividend yield — — — — Volatility 70.97% 72.28% 76.85% 72.04% Risk-free interest rate 1.78% 1.07% 1.81% 1.1% Expected life of options 6.00 years 6.00 years 6.00 years 6.00 years Weighted average grant date fair value $ 1.25 $ 2.57 $ 1.73 $ 2.44 The assumed dividend yield was based on the Company’s expectation of not paying dividends in the foreseeable future. Due to the Company’s limited historical data as an early-stage commercial business, the estimated volatility incorporates the historical and implied volatility of comparable companies whose share prices are publicly available. The risk-free interest rate assumption was based on U.S. Treasury rates. The weighted average expected life of options was estimated using the average of the contractual term and the weighted average vesting term of the options. Certain options granted to consultants are subject to variable accounting treatment and are required to be revalued until vested. The fair value of each restricted stock unit and performance-based restricted stock unit is recognized as stock-based compensation expense over the vesting term of the award. The fair value is based on the closing stock price on the date of the grant. The fair value of each restricted stock award is recognized as stock-based compensation expense over the vesting term of the award. The fair value is based on the closing stock price on the date of the grant. The Company uses the Black-Scholes valuation model to calculate the fair value of shares issued pursuant to the Company’s ESPP. Stock-based compensation expense is recognized over the purchase period using the straight-line method. The fair value of ESPP shares was estimated at the purchase period commencement date using the following assumptions: Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2017 September 30, 2016 September 30, 2017 September 30, 2016 Dividend yield — — — — Volatility 43.03 - 74.70% 72.89% 43.03 - 74.70% 72.89% Risk-free interest rate 0.79 - 1.10% 0.47% 0.79 - 1.10% 0.47% Expected term 6 months 6 months 6 months 6 months Weighted average grant date fair value $0.52 - $1.04 $1.22 $0.52 - $1.04 $1.22 The assumed dividend yield was based on the Company’s expectation of not paying dividends in the foreseeable future. For the first full year of ESPP offering periods, beginning September 1, 2016, due to the Company’s limited historical data as an early-stage commercial business, the estimated volatility incorporates the historical and implied volatility of comparable companies whose share prices are publicly available. As of September 1, 2017 and the beginning of the second year of ESPP offering periods, the Company is using our Company-specific volatility rate. The risk-free interest rate assumption was based on U.S. Treasury rates. The expected life is the 6-month purchase period. Preferred stock The Company is authorized to issue 25,000,000 shares of preferred stock. There are no shares of preferred stock currently outstanding, and the Company has no current plans to issue shares of preferred stock. Common stock In May 2008, the Board of Directors of the Company approved the 2008 Equity Incentive Plan (the “2008 Plan”). The 2008 Plan authorized the issuance of up to 1,521,584 common shares for awards of incentive stock options, non-statutory stock options, restricted stock awards, restricted stock award units, and stock appreciation rights. The 2008 Plan terminates on July 1, 2018. No shares have been issued under the 2008 Plan since 2011, and the Company does not intend to issue any additional shares from the 2008 Plan in the future. In January 2012, the Board of Directors of the Company approved the 2012 Equity Incentive Plan (the “2012 Plan”). The 2012 Plan authorized the issuance of up to 6,553,986 shares of common stock for awards of incentive stock options, non-statutory stock options, stock appreciation rights, restricted stock, restricted stock units, performance units, performance shares, and other stock or cash awards. The Board of Directors and stockholders of the Company approved an amendment to the 2012 Plan in August 2013 to increase the number of shares of common stock that may be issued under the 2012 Plan by 5,000,000 shares. In addition, the Board of Directors and stockholders of the Company approved an amendment to the 2012 Plan in August 2015 to further increase the number of shares of common stock that may be issued under the 2012 Plan by 6,000,000 shares, bringing the aggregate shares issuable under the 2012 Plan to 17,553,986. The 2012 Plan as amended and restated became effective on August 20, 2015 and terminates ten years after such date. As of September 30, 2017, 2,117,682 shares remain available for issuance under the 2012 Plan. On April 24, 2017, the Company filed a Registration Statement on Form S-8 with the SEC authorizing the issuance of 2,297,034 shares of the Company’s common stock, pursuant to the terms of an Inducement Award Stock Option Agreement and an Inducement Award Performance-Based Restricted Stock Unit Agreement (collectively, the “Inducement Award Agreements”). The Company filed a shelf registration statement on Form S-3 (File No. 333-189995), or the 2013 Shelf, with the SEC on July 17, 2013 authorizing the offer and sale in one or more offerings of up to $100,000,000 in aggregate of common stock, preferred stock, debt securities, or warrants to purchase common stock, preferred stock or debt securities, or any combination of the foregoing, either individually or as units comprised of one or more of the other securities. The 2013 Shelf was declared effective by the SEC on July 26, 2013 and was terminated in 2016. A shelf registration statement on Form S-3 (File No. 333-202382), or the 2015 shelf, was filed with the SEC on February 27, 2015 authorizing the offer and sale in one or more offerings of up to $190,000,000 in aggregate of common stock, preferred stock, debt securities, warrants to purchase common stock, preferred stock or debt securities, or any combination of the foregoing, either individually or as units comprised of one or more of the other securities. The 2015 shelf was declared effective by the SEC on March 17, 2015. In December 2014, the Company entered into an equity offering sales agreement, or the 2014 Sales Agreement, with an investment banking firm. Under the terms of the distribution agreement, the Company could offer and sell up to $30,000,000 of its shares of common stock, from time to time, through the investment bank in at-the-market offerings, as defined by the SEC, and pursuant to the 2013 Shelf. On July 20, 2016, the Company filed a prospectus supplement to move the remaining $26.6 million of common stock that previously could have been sold pursuant to the 2014 Sales Agreement under the 2013 Shelf to the 2015 Shelf, which does not expire until March 17, 2018. On that same date, the Company filed a post-effective amendment to the 2013 Shelf de-registering all remaining securities that could have been offered by the Company pursuant to the 2013 Shelf. On June 23, 2015, the Company closed the public offering of 10,838,750 shares of its common stock (the “2015 Offering”), which included the full exercise of the underwriters’ over-allotment. The 2015 Offering was effected pursuant to an Underwriting Agreement (the “2015 Underwriting Agreement”), dated June 18, 2015, with Jefferies LLC and Piper Jaffray & Co. (the “Representatives”), acting as representatives of the underwriters named in the 2015 Underwriting Agreement. The price to the public in the 2015 Offering was $4.25 per share, and the Underwriters agreed to purchase the shares from the Company pursuant to the 2015 Underwriting Agreement at a price of $3.995 per share. On October 25, 2016, the Company closed the public offering of 10,065,000 shares (the “2016 Offering”) of its common stock, which included partial exercise of the underwriters’ over-allotment. The 2016 Offering was effected pursuant to an Underwriting Agreement (the “2016 Underwriting Agreement”), dated October 20, 2016, with Jefferies LLC (the “Representative”), acting as representative of the underwriters named in the 2016 Underwriting Agreement. The price to the public in the 2016 Offering was $2.75 per share, and the underwriters purchased the shares from the Company pursuant to the 2016 Underwriting Agreement at a price of $2.585 per share. The net proceeds to the Company from the 2016 Offering were approximately $25.7 million after deducting underwriting discounts and commissions and expenses payable by the Company. The 2016 Offering was made pursuant to the 2015 Shelf. During the three months ended September 30, 2017 and 2016, the Company issued 0 and 123,104 shares of common stock upon the exercise of 0 and 160,000 warrants, respectively. During the six months ended September 30, 2017 and 2016, the Company issued 0 and 123,104 shares of common stock up on the exercise of 0 and 160,000 warrants, respectively. During the three months ended September 30, 2017 and 2016, the Company issued 500,000 and 206,266 shares of common stock upon the exercise of 500,000 and 206,266 stock options, respectively. During the six months ended September 30, 2017 and 2016, the Company issued 500,000 and 206,266 shares of common stock upon the exercise of 500,000 and 206,266 stock options, respectively. Restricted stock awards During the three months ended September 30, 2017 and 2016, there were 0 and 0 shares of restricted stock, respectively, cancelled related to shares of common stock returned to the Company, at the option of the holders, to cover the tax liability related to the vesting of 0 and 0 restricted stock awards, respectively. During the six months ended September 30, 2017 and 2016, there were 0 and 2,259 shares of restricted stock, respectively, cancelled related to shares of common stock returned to the Company, at the option of the holders, to cover the tax liability related to the vesting of 0 and 6,250 restricted stock awards, respectively. Upon the return of the common stock, an equal number of stock options with immediate vesting were granted to the individuals at the vesting date market value strike price. Restricted stock units During the three and six months ended September 30, 2017, the Company issued restricted stock units for an aggregate of 7,000 and 1,869,078 shares of common stock, respectively, to its employees and directors. These shares of common stock will be issued upon vesting of the restricted stock units. Vesting generally occurs (i) on the one-year anniversary of the grant date, (ii) quarterly over a three-year period, (iii) quarterly over a four-year period, (iv) over a four-year period, with 25% vesting on the one-year anniversary of the vesting commencement date and the remainder vesting ratably on a quarterly basis over the next twelve quarters, or (v) over a three-year period with 50% vesting on the two-year anniversary of the vesting commencement date and 50% vesting on the three-year anniversary of the vesting commencement date. A summary of the Company’s restricted stock unit (not including performance-based restricted stock units) activity from March 31, 2017 through September 30, 2017 is as follows: Number of Shares Weighted Average Price Unvested at March 31, 2017 1,178,114 $ 3.57 Granted 1,869,078 $ 2.66 Vested (263,594 ) $ 3.45 Cancelled / forfeited (154,924 ) $ 3.04 Unvested at September 30, 2017 2,628,674 $ 2.96 Performance-based restricted stock units On April 24, 2017, in connection with the appointment of a new CEO, the Company allocated 208,822 Performance-Based Restricted Stock Units outside of the 2012 Plan. The Company intends for these to be “inducement awards” within the meaning of NASDAQ Marketplace Rule 5635(c)(4). While outside the Company’s 2012 Plan, the terms and conditions of these awards are consistent with awards granted to the Company’s executive officers pursuant to the 2012 Plan. On August 23, 2017, the Board of Directors formally approved the vesting criteria for the Performance-Based Restricted Stock Units (“PBRSUs”) allocated by the Company on April 24, 2017. The units are divided into five separate tranches each with independent vesting criteria. The first four tranches have performance criteria related to annual revenue goals with measurement at the end of fiscal year 2018 (20 percent), fiscal year 2019 (20 percent), fiscal year 2020 (20 percent), and fiscal year 2021 (20 percent). The fifth tranche has a performance metric related to a path to profitability goal measured as Negative Adjusted EBITDA achievable at any point between the grant date and the end of fiscal year 2020 (20 percent). The number of units that ultimately vest for each tranche will range from 0 percent to 120 percent of the target amount, not to exceed 208,822 in aggregate. As of September 30, 2017, no tranches had vested and 100% of current year tranches are expected to vest. The grant date fair values of the tranches are collectively $393,000 of which one-fifth is being recognized over each tranches’ service period. The Company began recording stock-based compensation expense for these tranches after the August 23, 2017 grant date when the financial performance goals were established and approved. As of September 30, 2017, PBRSUs from the fiscal year 2018 tranche and the Negative Adjusted EBITDA tranche have begun vesting and are expected to vest in the amount of 83,530 shares. A summary of the Company’s performance-based restricted stock unit activity from March 31, 2017 through September 30, 2017 is as follows: Number of Shares Weighted Average Price Unvested at March 31, 2017 — $ — Granted 208,822 $ 1.88 Vested — $ — Cancelled / forfeited — $ — Unvested at September 30, 2017 208,822 $ 1.88 Stock options Under the 2012 Plan, 260,000 and 1,386,500 stock options were issued during the three months ended September 30, 2017 and 2016, respectively, and 2,366,812 and 1,803,140 stock options were issued during the six months ended September 30, 2017 and 2016, respectively, at various exercise prices based on the closing market price of the Company’s common stock on the date of the grant. The stock options generally vest (i) on the one-year anniversary of the grant date, (ii) quarterly over a three-year period, or (iii) over a four-year period with a quarter vesting on either the one year anniversary of employment or the one year anniversary of the vesting commencement date, and the remainder vesting ratably over the remaining 36 month terms. Stock options can also vest immediately at the grant date or vest after one full year. On April 24, 2017, in connection with the appointment of a new CEO, the Company granted 2,088,212 stock options outside of the 2012 Plan. The Company intends for these to be “inducement grants” within the meaning of NASDAQ Marketplace Rule 5635(c)(4). While granted outside the Company’s 2012 Plan, the terms and conditions of these awards are consistent with awards granted to the Company’s executive officers pursuant to the 2012 Plan. These stock options vest A summary of the Company’s stock option activity from March 31, 2017 to September 30, 2017 is as follows: Options Outstanding Weighted- Average Exercise Price Aggregate Intrinsic Value Outstanding at March 31, 2017 10,956,201 $ 4.63 $ 4,876,437 Options granted 2,366,812 $ 2.65 $ — Options cancelled / forfeited (493,050 ) $ 4.41 $ — Options exercised (500,000 ) $ 1.65 $ 235,000 Outstanding at September 30, 2017 12,329,963 $ 4.38 $ 1,812,776 Vested and Exercisable at September 30, 2017 7,265,871 $ 4.92 $ 1,723,601 The weighted-average remaining contractual term of options exercisable and outstanding at September 30, 2017 was approximately 6 years. Employee Stock Purchase Plan In June 2016, our Board of Directors adopted, and in August 2016 stockholders subsequently approved, the 2016 Employee Stock Purchase Plan. We reserved 1,500,000 shares of common stock for issuance thereunder. The ESPP permits employees after five months of service to purchase common stock through payroll deductions, limited to 15 percent of each employee’s compensation up to the lower of $25,000 or 10,000 shares per employee per year. Shares under the ESPP are purchased at 85 percent of the fair market value at the lower of (i) the closing price on the first trading day of the six-month purchase period or (ii) the closing price on the last trading day of the six-month purchase period. The initial offering period commenced in September 2016. At September 30, 2017, there were 1,372,960 shares available for purchase under the ESPP. Warrants During the three and six months ended September 30, 2017, there were no warrant exercises. During the three and six months ended September 30, 2016, 160,000 warrants were exercised through a cashless exercise provision in exchange for the issuance of 123,104 shares of common stock. The following table summarizes warrant activity for the six months ended September 30, 2017: Warrants Weighted- Average Exercise Price Balance at March 31, 2017 221,370 $ 7.16 Granted — $ — Exercised — $ — Cancelled — $ — Balance at September 30, 2017 221,370 $ 7.16 The warrants outstanding at September 30, 2017 are exercisable at prices between $2.28 and $7.62 per share, and have a weighted average remaining term of approximately 1.36 years. Common stock reserved for future issuance Common stock reserved for future issuance consisted of the following at September 30, 2017: Common stock warrants outstanding 221,370 Common stock options outstanding under the 2008 Plan 622,192 Common stock options outstanding and reserved under the 2012 Plan 11,737,241 Common stock reserved under the 2016 Employee Stock Purchase Plan 1,372,960 Restricted stock units outstanding under the 2012 Plan 2,628,674 Common stock options outstanding and reserved under the Inducement Awards 2,088,212 Restricted stock units outstanding under the Inducement Awards 208,822 Total at September 30, 2017 18,879,471

Commitments and Contingencies

Commitments and Contingencies	6 Months Ended
	Sep. 30, 2017
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies	Note 3. Commitments and Contingencies Operating leases The Company leases laboratory and office space in San Diego, California under two non-cancelable leases as described below. Since July 2012, the Company has leased its main facilities at 6275 Nancy Ridge Drive, San Diego, California 92121. The lease, as amended in 2013, 2015 and 2016, consists of approximately 45,580 rentable square feet containing laboratory, clean room and office space. Monthly rental payments are currently approximately $120,000 per month with 3% annual escalators. The lease term for 14,685 of the total rentable square footage expires on December 15, 2018, with the remainder of the rentable square footage expiring on September 1, 2021 with the Company having an option to terminate this lease on or after September 1, 2019. On January 9, 2015, the Company entered into an agreement to lease a second facility consisting of 5,803 rentable square feet of office and lab space located at 6310 Nancy Ridge Drive, San Diego, California 92121. The term of the lease is 36 months, beginning on February 1, 2015 and ending on January 31, 2018, with monthly rental payments of approximately $12,000 commencing on April 1, 2015. In addition, there are annual rent escalations of 3% on each 12-month anniversary of the lease commencement date. In addition to these two leases, the Company leased a third facility from February 1, 2016 through January 31, 2017, consisting of 12,088 rentable square feet of office space located at 6166 Nancy Ridge Drive, San Diego, California 92121 with a monthly rent of $15,000. The Company records rent expense on a straight-line basis over the life of the leases and records the excess of expense over the amounts paid as deferred rent. In addition, one of the leases provides for certain improvements made for the Company’s benefit to be funded by the landlord. Such costs, totaling approximately $518,000 to date, have been capitalized as fixed assets and included in deferred rent. Rent expense was approximately $365,000 and $302,000 for the three months ended September 30, 2017 and 2016, respectively, and $731,000 and $605,000 for the six months ended September 30, 2017 and 2016, respectively. Future minimum rental payments required under operating leases that have initial or remaining non-cancelable lease terms in excess of one year as of September 30, 2017, are as follows (in thousands): Fiscal year ended March 31, 2018 794 Fiscal year ended March 31, 2019 1,465 Fiscal year ended March 31, 2020 1,073 Fiscal year ended March 31, 2021 1,104 Fiscal year ended March 31, 2022 467 Thereafter — Total 4,903 Legal Matters In addition to commitments and obligations in the ordinary course of business, the Company may be subject, from time to time, to various claims and pending and potential legal actions arising out of the normal conduct of its business. The Company assesses contingencies to determine the degree of probability and range of possible loss for potential accrual in its financial statements. Because litigation is inherently unpredictable and unfavorable resolutions could occur, assessing litigation contingencies is highly subjective and requires judgments about future events. When evaluating contingencies, the Company may be unable to provide a meaningful estimate due to a number of factors, including the procedural status of the matter in question, the presence of complex or novel legal theories, and/or the ongoing discovery and development of information important to the matters. In addition, damage amounts claimed in litigation against it may be unsupported, exaggerated or unrelated to possible outcomes, and as such are not meaningful indicators of its potential liability. The Company regularly reviews contingencies to determine the adequacy of its accruals and related disclosures. During the period presented, the Company has not recorded any accrual for loss contingencies associated with such claims or legal proceedings; determined that an unfavorable outcome is probable or reasonably possible; or determined that the amount or range of any possible loss is reasonably estimable. However, the outcome of legal proceedings and claims brought against the Company is subject to significant uncertainty. Therefore, although management considers the likelihood of such an outcome to be remote, if one or more of these legal matters were resolved against the Company in a reporting period, the Company’s consolidated financial statements for that reporting period could be materially adversely affected.

Concentrations

Concentrations	6 Months Ended
	Sep. 30, 2017
Risks And Uncertainties [Abstract]
Concentrations	Note 4. Concentrations Credit risk Financial instruments that potentially subject the Company to concentrations of credit risk consist principally of temporary cash investments. The Company maintains cash balances at various financial institutions primarily located within the United States. Accounts at these institutions are secured by the Federal Deposit Insurance Corporation. Balances may exceed federally insured limits. The Company has not experienced losses in such accounts, and management believes that the Company is not exposed to any significant credit risk with respect to its cash and cash equivalents. The Company is also potentially subject to concentrations of credit risk in its revenues and accounts receivable. Because it is in the early commercial stage, the Company’s revenues to date have been derived from a relatively small number of customers and collaborators. However, the Company has not historically experienced any accounts receivable write-downs and management does not believe significant credit risk exists as of September 30, 2017.

Related Parties

Related Parties	6 Months Ended
	Sep. 30, 2017
Related Party Transactions [Abstract]
Related Parties	Note 5. Related Parties The Company has entered into two agreements with related parties in the ordinary course of its business and on terms and conditions it believes are as fair as those it offers and receives from independent third parties. Each agreement was ratified by the Company’s Board of Directors or a committee thereof pursuant to its related party transaction policy. In August 2017, the Company entered into a services agreement with Cirius Tx, Inc., an entity for which Robert Baltera, Jr., a director of the Company, serves as Chief Executive Officer. Under this agreement, the Company has provided ExVive™ Liver Tissue Services for Cirius amounting to $50,000 in the three and six months ended September 30, 2017. The agreement contains another $44,000 of ExVive™ Liver Tissue Services to be completed in the third quarter of fiscal 2018. In November 2017, the Company entered into a collaboration agreement with Viscient Biosciences, an entity which Keith Murphy, a former director and Chief Executive Officer of the Company, serves as Chief Executive Officer. Under this agreement, the parties intend to develop a custom research platform for studying liver disease. The Company expects the platform to expand its current service portfolio for compound screening in disease models, which aids the drug discovery work for other customers. Viscient intends to target early discovery work for non-alcoholic fatty liver disease (“NAFLD”) and non-alcoholic steatohepatitis (“NASH”). Under this agreement, the Company will provide research services to Viscient amounting to $287,000 to be completed in fiscal 2018. For the three and six months ended September 30, 2017, this contract had no financial impact.

Recent Accounting Pronouncement

Recent Accounting Pronouncements	6 Months Ended
	Sep. 30, 2017
Accounting Changes And Error Corrections [Abstract]
Recent Accounting Pronouncements	Note 6. Recent Accounting Pronouncements In May 2014, the FASB issued Accounting Standards Update (“ASU”) No. 2014-09, Revenue from Contracts with Customers, which requires an entity to recognize the amount of revenue to which it expects to be entitled for the transfer of promised goods or services to customers. The standard will replace most existing revenue recognition guidance in U.S. GAAP when it becomes effective. The new standard was originally effective for public companies for annual reporting periods beginning after December 15, 2016, with no early application permitted. In August 2015, the FASB issued ASU No. 2015-14 that defers by one year the effective date for all entities, with application permitted as of the original effective date. The updated standard becomes effective for us on April 1, 2018, with early adoption permitted as of April 1, 2017. The standard permits the use of either the retrospective or cumulative effect transition method. We are evaluating the effect that this update will have on our consolidated financial statements and related disclosures. We have not yet selected a transition method nor have we determined the effect of this updated standard on our ongoing financial reporting. We do not have plans to adopt this standard prior to the effective date. In February 2016, the FASB issued ASU 2016-02, Leases, which requires an entity to recognize lease assets and lease liabilities on the balance sheet for leases with terms of more than 12 months and to disclose key information about leasing arrangements. This new guidance is effective for us on April 1, 2019, with early adoption permitted in any interim or annual period. The Company is currently evaluating the impact that this guidance will have on its financial statements and related disclosures. In March 2016, the FASB issued ASU 2016-09, Compensation-Stock Compensation (Topic 718), which requires an entity recognize excess tax benefits and deficiencies as income tax expense or benefit, the cash flows of which should be included as operating activity in the statement of cash flows. An entity is allowed to either continue accruing compensation cost based on expected forfeitures or to begin recognizing expense as forfeitures occur. In addition, an entity may withhold the maximum statutory tax, increasing the allowable cash settlement portion of awards. The cash paid by an employer when directly withholding shares for tax purposes should be included in the financing activity section of the statement of cash flows. This new guidance became effective for us on April 1, 2017. The requirements of ASU 2016-09 did not have a significant impact on our consolidated financial statements.

Subsequent Events

Subsequent Events	6 Months Ended
	Sep. 30, 2017
Subsequent Events [Abstract]
Subsequent Events	Note 7. Subsequent Events On October 4, 2017, the Company announced a plan to restructure its business to better focus and align resources, reducing approximately 15 positions, or 13% of its overall workforce. The internal reorganization intends to improve operational efficiency, consolidate overlapping positions, and streamline the Company’s management structure. As a result, the Company expects to record a restructuring charge in the fiscal third quarter of approximately $0.9 million, primarily related to employee severance and benefits costs. The actions associated with the restructuring announcement are anticipated to be complete by the end of fiscal third quarter 2018 with liabilities anticipated to be paid by the end of fiscal third quarter 2019. In November 2017, the Company entered into a collaboration agreement with Viscient Biosciences, an entity which Keith Murphy, a former director and Chief Executive Officer of the Company, serves as Chief Executive Officer. See Note 5 for discussion of Related Parties.

Description of Business and S13

Description of Business and Summary of Significant Accounting Policies (Policies)	6 Months Ended
	Sep. 30, 2017
Accounting Policies [Abstract]
Nature of Operations and Basis of Presentation	Nature of operations and basis of presentation References in these notes to the unaudited condensed consolidated financial statements to “Organovo Holdings, Inc.,” “Organovo Holdings,” “we,” “us,” “our,” “the Company” and “our Company” refer to Organovo Holdings, Inc. and its consolidated subsidiaries. Our consolidated financial statements include the accounts of the Company as well as its wholly-owned subsidiaries, with all material intercompany accounts and transactions eliminated in consolidation. In December 2014, we established a wholly-owned subsidiary, Samsara Sciences, Inc., to focus on the acquisition of qualified cells in support of our commercial and research endeavors. In September 2015, we established another wholly-owned subsidiary in the United Kingdom, Organovo U.K., Ltd., for the primary purpose of establishing a sales presence in Europe. Since its inception, the Company has devoted its efforts primarily to developing and commercializing a platform technology and functional human tissues that can be employed in drug discovery and development, biological research, and as therapeutic implants for the treatment of damaged or degenerating tissues and organs. The Company has also focused efforts on raising capital and building infrastructure. In November 2014, the Company announced the commercial release of its first product, the ExVive™ Human Liver Tissue for use in toxicology and other drug testing. In September 2016, the Company announced that it had begun commercial contracting for services relating to its second product, the ExVive™ Human Kidney tissue. The Company’s activities are subject to significant risks and uncertainties including failing to successfully develop products and services based on its technology and to achieve the market acceptance necessary to generate sufficient revenues to support its operations and to achieve and sustain profitability. The accompanying interim condensed consolidated financial statements have been prepared by the Company, without audit, in accordance with the instructions to Form 10-Q and, therefore, do not necessarily include all information and footnotes necessary for a fair statement of its financial position, results of operations, stockholders’ equity and cash flows in accordance with generally accepted accounting principles (“GAAP”). The balance sheet at March 31, 2017 is derived from the Company’s audited balance sheet at that date. In the opinion of management, the unaudited financial information for the interim periods presented reflects all adjustments, which are only normal and recurring, necessary for a fair statement of the Company’s financial position, results of operations, stockholders’ equity and cash flows. These financial statements should be read in conjunction with the financial statements included in the Company’s Annual Report on Form 10-K for the year ended March 31, 2017, filed with the Securities and Exchange Commission (the “SEC”) on June 7, 2017. Operating results for interim periods are not necessarily indicative of operating results for the Company’s fiscal year ending March 31, 2018.
Liquidity	Liquidity As of September 30, 2017, the Company had cash and cash equivalents of approximately $50.7 million and an accumulated deficit of approximately $218.9 million. The Company also had negative cash flows from operations of approximately $16.8 million during the six months ended September 30, 2017. Through September 30, 2017, the Company has financed its operations primarily through the sale of convertible notes, the private placement of equity securities, the sale of common stock through public and at-the-market (“ATM”) offerings, and through revenue derived from product and research service-based agreements, collaborative research agreements, grants, and licenses. During the six months ended September 30, 2017, the Company issued 1,538,217 shares of its common stock through its ATM facility and received net proceeds of approximately $4.0 million. On October 25, 2016, the Company closed the issuance and sale of 10,065,000 shares of its common stock in an underwritten public offering. The Company received net proceeds of approximately $25.7 million in the offering, after deducting underwriting discounts and commissions and the Company’s expenses. Based on its current operating plan and available cash resources, the Company has sufficient resources to fund its business for at least the next twelve months from the financial statement issuance date. The Company will need additional capital to further fund the development and commercialization of its human tissues that can be employed in drug discovery and development, biological research, and as therapeutic implants for the treatment of damaged or diseased tissues and organs. The Company intends to cover its future operating expenses through cash on hand, through revenue derived from research service agreements, product sales, collaborative research agreements, grants and royalty payments, and through the issuance of additional equity or debt securities. Depending on market conditions, we cannot be sure that additional financing will be available when needed or that, if available, financing will be obtained on terms favorable to us or to our stockholders. Having insufficient funds may require us to delay, scale back, or eliminate some or all of our development programs or relinquish rights to our technology on less favorable terms than we would otherwise choose. Failure to obtain adequate financing could eventually adversely affect our ability to operate as a going concern. If we raise additional funds from the issuance of equity securities, substantial dilution to our existing stockholders would likely result. If we raise additional funds by incurring debt financing, the terms of the debt may involve significant cash payment obligations as well as covenants and specific financial ratios that may restrict our ability to operate our business.
Use of estimates	Use of estimates The preparation of the financial statements in conformity with accounting principles generally accepted in the United States requires management to make estimates and assumptions that affect certain reported amounts and disclosures. Accordingly, actual results could differ from those estimates. Significant estimates used in preparing the condensed consolidated financial statements include those assumed in revenue recognized under the proportional performance model, the valuation of stock-based compensation expense, and the valuation allowance on deferred tax assets.
Fair value measurement	Fair value measurement The Company had issued warrants, of which some were classified as derivative liabilities as a result of the terms in the warrants that provide for down-round protection in the event of a dilutive issuance. The Company used Level 3 inputs (unobservable inputs that are supported by little or no market activity, and that are significant to the fair value of the assets or liabilities) for its valuation methodology for the warrant derivative liabilities. The estimated fair values were determined using a Monte Carlo option pricing model based on various assumptions. The Company’s derivative liabilities were adjusted to reflect estimated fair value at each period end, with any increase or decrease in the estimated fair value being recorded in other income or expense accordingly, as adjustments to the fair value of the derivative liabilities. Various factors are considered in the pricing models the Company used to value the warrants, including the Company’s current stock price, the remaining life of the warrant, the volatility of the Company’s stock price, and the risk-free interest rate. The remaining warrants expired as of March 31, 2017 and were removed from the Balance Sheet. The Company does not have any financial assets or liabilities measured on a fair value basis as of September 30, 2017 or March 31, 2017.
Revenue recognition	Revenue recognition The Company’s revenues are derived from research service agreements, product sales, and collaborative research agreements with pharmaceutical and biotechnology companies, as well as grants and license-payments from the National Institutes of Health (“NIH”), U.S. Treasury Department, academic institutions, and private not-for-profit organizations. The Company recognizes revenue when the following criteria have been met: (i) persuasive evidence of an arrangement exists; (ii) services have been rendered or product has been delivered; (iii) price to the customer is fixed and determinable; and (iv) collection of the underlying receivable is reasonably assured. Billings to customers or payments received from customers are included in deferred revenue on the balance sheet until all revenue recognition criteria are met. As of September 30, 2017 and March 31, 2017, the Company had approximately $721,000 and $640,000, respectively, in deferred revenue related to its grants and royalty payments, collaborative research programs and research service agreements.
Revenue arrangements with multiple deliverables	Revenue arrangements with multiple deliverables The Company follows ASC 605-25 Revenue Recognition – Multiple-Element Arrangements While changes in the allocation of the arrangement consideration between the units of accounting will not affect the amount of total revenue recognized for a particular sales arrangement, any material changes in these allocations could impact the timing of revenue recognition, which could affect the Company’s results of operations. The Company periodically receives license fees for non-exclusive research licensing associated with funded research projects. License fees under these arrangements are recognized over the term of the contract or development period as it has been determined that such licenses do not have stand-alone value.
Revenue from research service agreements	Revenue from research service agreements For research service agreements that contain only a single or primary deliverable, the Company defers any up-front fees collected from customers, and recognizes revenue for the delivered element only when it determines there are no uncertainties regarding customer acceptance. For agreements that contain multiple deliverables, the Company follows ASC 605-25 as described above.
Research and development revenue under collaborative agreements	Research and development revenue under collaborative agreements The Company’s collaboration revenue consists of license and collaboration agreements that contain multiple elements, which may include non-refundable up-front fees, payments for reimbursement of third-party research costs, payments for ongoing research, payments associated with achieving specific development milestones and royalties based on specified percentages of net product sales, if any. The Company considers a variety of factors in determining the appropriate method of revenue recognition under these arrangements, such as whether the elements are separable, whether there are determinable fair values and whether there is a unique earnings process associated with each element of a contract. The Company recognizes revenue from research funding under collaboration agreements when earned on a “proportional performance” basis as research services are provided or substantive milestones are achieved. We recognize revenue that is contingent upon the achievement of a substantive milestone in its entirety in the period in which the milestone is achieved. A milestone is considered substantive when the consideration payable to us for the milestone (i) is consistent with our performance necessary to achieve the milestone or the increase in value to the collaboration resulting from our performance, (ii) relates solely to our past performance and (iii) is reasonable relative to all of the other deliverables and payments within the arrangement. In making this assessment, we consider all facts and circumstances relevant to the arrangement, including factors such as the risks that must be overcome to achieve the milestone, the level of effort and investment required to achieve the milestone and whether any portion of the milestone consideration is related to future performance or deliverables. The Company initially defers revenue for any amounts billed or payments received in advance of the services being performed, and recognizes revenue pursuant to the related pattern of performance, using the appropriate method of revenue recognition based on its analysis of the related contractual element(s). In November 2014, the Company entered into a collaborative non-exclusive research affiliation with a university medical school and a non-profit medical charity, under which the Company received a one-time grant from the charity towards the placement of a NovoGen Bioprinter at the university for the purpose of developing bioprinted tissues for surgical transplantation research. The Company has recorded $0 and $12,500 for the three months ended September 30, 2017 and 2016 and $0 and $25,000 for the six months ended September 30, 2017 and 2016, respectively, in revenue related to this collaboration in recognition of the proportional performance achieved. In April 2015, the Company entered into a research collaboration agreement with a third party to develop custom tissue models for fixed fees. Based on the proportional performance achieved under this agreement, $150,000 in collaboration revenue was recorded for the three and six months ended September 30, 2017, and $0 collaboration revenue was recorded for the three and six months ended September 30, 2016. Approximately $620,000 in collaboration revenue has been recognized to date under this agreement as of September 30, 2017. Also in April 2015, the Company entered into a multi-year research agreement with a third party to develop multiple custom tissue models for use in drug development. No collaboration revenue was recorded under this agreement during the three and six months ended September 30, 2017. Approximately $332,000 and $533,000 were recorded as revenue in recognition of the proportional performance achieved under this agreement during the three and six months ended September 30, 2016, respectively. In June 2016, the Company announced it had entered into another collaborative non-exclusive research affiliation with a university medical school and a non-profit medical charity, under which the Company received a one-time grant from the charity towards the placement of a NovoGen Bioprinter at the university for the purpose of developing bioprinted tissues for skeletal disease research. The Company received an up-front payment in June 2016, which was initially recorded as deferred revenue. Revenue of $18,000 and $35,000 has been recorded under this agreement during the three and six months ended September 30, 2017, respectively. No revenue was recorded under this agreement as of September 30, 2016. In December 2016, the Company signed another collaborative non-exclusive research affiliation with a university medical school and a non-profit medical charity, under which the Company received a one-time grant from the charity towards the placement of a NovoGen Bioprinter at the university for the purpose of developing an architecturally correct kidney for potential therapeutic applications. The Company received an up-front payment in January and March of 2017, which has been recorded as deferred revenue. Revenue of $9,000 and $19,000 has been recorded under this agreement for the three and six months ended September 30, 2017, respectively. In April 2017, the Company signed a collaborative non-exclusive research affiliation with a university, under which the Company received a one-time non-refundable payment toward the placement of a NovoGen Bioprinter at the university for the purpose of specific research projects mutually agreed by the university and the Company in the field of volumetric muscle loss. The Company received an up-front payment in May of 2017, which has been recorded as deferred revenue. Revenue of approximat ely $14,000 has been recorded under this agreement for the three and six months ended September 30, 2017, beginning subsequent to the installation of the printer in July 2017. In addition, during April 2017, the Company signed a Non-exclusive Patent License agreement with the university including an annual fee of $75,000 for each of the two years for the license to the Company Patents for research use limited to the field of volumetric muscle loss. The Company received the first annual payment of $75,000 in April of 2017, which has been recorded as deferred revenue. Revenue of $18,750 and $37,500 has been recorded under this agreement for the three and six months ended September 30, 2017. In September 2017, the Company entered into an agreement with a company, under which the Company received a one-time non-refundable payment of $50,000 for limited use of a Company Patent in reference to four bioprinters developed and placed at research and academic facilities. The Company has recorded $50,000 for the three months and six months ended September 30, 2017.
Product revenue	Product revenue The Company recognizes product revenue at the time of shipment to the customer, provided all other revenue recognition criteria have been met. As our commercial sales increase, we expect to establish a reserve for estimated product returns that will be recorded as a reduction to revenue. This reserve will be maintained to account for future return of products sold in the current period. The reserve will be reviewed quarterly and will be estimated based on an analysis of our historical experience related to product returns.
Grant revenue	Grant revenue During August 2013, the Company was awarded a research grant by a private, not-for-profit organization for up to $251,700, contingent on go/no-go decisions made by the grantor at the completion of each stage of research as outlined in the grant award. Revenues from the grant are based upon internal costs incurred that are specifically covered by the grant, plus an additional rate that provides funding for overhead expenses. Revenue is recognized when the Company incurs expenses that are related to the grant. Revenue recognized under this grant was approximately $0 and $8,000 for each of the three months ended September 30, 2017 and 2016 and $0 and $12,000 for each of the six months ended September 30, 2017 and 2016, respectively. The Company has completed its obligations under this agreement as of March 31, 2017. During July 2017, the NIH awarded the Company a research grant totaling approximately $1,657,000. The grant provides for fixed payments based on the achievement of certain milestones. Revenue is recognized upon completion of substantive milestones. Revenue recognized under this grant was approximately $149,000 for the three and six months ended September 30 , 2017.
Cost of revenues	Cost of revenues The Company reported $0.3 million and $0.6 million in cost of revenues for the three and six months ended September 30, 2017, respectively. The Company reported $0.4 million and $0.6 million in cost of revenues for the three and six months ended September 30, 2016, respectively. This captures our costs related to manufacturing and delivering our product and service revenue.
Net loss per share	Net loss per share Basic and diluted net loss per share has been computed using the weighted-average number of shares of common stock outstanding during the period. The weighted-average number of shares used to compute diluted loss per share excludes any assumed exercise of stock options and warrants, shares reserved for purchase under the Company’s 2016 Employee Stock Purchase Plan (“ESPP”), the assumed release of restriction of restricted stock units, and shares subject to repurchase as the effect would be anti-dilutive. No dilutive effect was calculated for the three and six months ended September 30, 2017 or 2016, as the Company reported a net loss for each respective period and the effect would have been anti-dilutive. Common stock equivalents excluded from computing diluted net loss per share were approximately 15.4 million at September 30, 2017, and 13.2 million at September 30, 2016.

Stockholders' Equity (Tables)

Stockholders' Equity (Tables)	6 Months Ended
	Sep. 30, 2017
Class Of Stock [Line Items]
Schedule of Stock-based Compensation Expense	Stock-based compensation expense for all stock awards consists of the following (in thousands): Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2017 September 30, 2016 September 30, 2017 September 30, 2016 Research and development $ 384 $ 379 $ 715 $ 787 General and administrative $ 1,914 $ 1,714 $ 3,635 $ 2,735 Total $ 2,298 $ 2,093 $ 4,350 $ 3,522
Fair Value of Employee Stock Options	The fair value of stock options was estimated at the grant date using the following weighted average assumptions: Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2017 September 30, 2016 September 30, 2017 September 30, 2016 Dividend yield — — — — Volatility 70.97% 72.28% 76.85% 72.04% Risk-free interest rate 1.78% 1.07% 1.81% 1.1% Expected life of options 6.00 years 6.00 years 6.00 years 6.00 years Weighted average grant date fair value $ 1.25 $ 2.57 $ 1.73 $ 2.44
Fair Value of Employee Stock Purchase Plan	The fair value of ESPP shares was estimated at the purchase period commencement date using the following assumptions: Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2017 September 30, 2016 September 30, 2017 September 30, 2016 Dividend yield — — — — Volatility 43.03 - 74.70% 72.89% 43.03 - 74.70% 72.89% Risk-free interest rate 0.79 - 1.10% 0.47% 0.79 - 1.10% 0.47% Expected term 6 months 6 months 6 months 6 months Weighted average grant date fair value $0.52 - $1.04 $1.22 $0.52 - $1.04 $1.22
Summary of Stock Option Activity	A summary of the Company’s stock option activity from March 31, 2017 to September 30, 2017 is as follows: Options Outstanding Weighted- Average Exercise Price Aggregate Intrinsic Value Outstanding at March 31, 2017 10,956,201 $ 4.63 $ 4,876,437 Options granted 2,366,812 $ 2.65 $ — Options cancelled / forfeited (493,050 ) $ 4.41 $ — Options exercised (500,000 ) $ 1.65 $ 235,000 Outstanding at September 30, 2017 12,329,963 $ 4.38 $ 1,812,776 Vested and Exercisable at September 30, 2017 7,265,871 $ 4.92 $ 1,723,601
Summary of Warrant Activity	The following table summarizes warrant activity for the six months ended September 30, 2017: Warrants Weighted- Average Exercise Price Balance at March 31, 2017 221,370 $ 7.16 Granted — $ — Exercised — $ — Cancelled — $ — Balance at September 30, 2017 221,370 $ 7.16
Common Stock Reserved for Future Issuance	Common stock reserved for future issuance consisted of the following at September 30, 2017: Common stock warrants outstanding 221,370 Common stock options outstanding under the 2008 Plan 622,192 Common stock options outstanding and reserved under the 2012 Plan 11,737,241 Common stock reserved under the 2016 Employee Stock Purchase Plan 1,372,960 Restricted stock units outstanding under the 2012 Plan 2,628,674 Common stock options outstanding and reserved under the Inducement Awards 2,088,212 Restricted stock units outstanding under the Inducement Awards 208,822 Total at September 30, 2017 18,879,471
Restricted stock units (RSUs) [Member]
Class Of Stock [Line Items]
Summary of Company's Restricted Stock Unit Activity and Performance Based Restricted Stock Unit Activity	A summary of the Company’s restricted stock unit (not including performance-based restricted stock units) activity from March 31, 2017 through September 30, 2017 is as follows: Number of Shares Weighted Average Price Unvested at March 31, 2017 1,178,114 $ 3.57 Granted 1,869,078 $ 2.66 Vested (263,594 ) $ 3.45 Cancelled / forfeited (154,924 ) $ 3.04 Unvested at September 30, 2017 2,628,674 $ 2.96
Performance-Based Restricted Stock Units [Member]
Class Of Stock [Line Items]
Summary of Company's Restricted Stock Unit Activity and Performance Based Restricted Stock Unit Activity	A summary of the Company’s performance-based restricted stock unit activity from March 31, 2017 through September 30, 2017 is as follows: Number of Shares Weighted Average Price Unvested at March 31, 2017 — $ — Granted 208,822 $ 1.88 Vested — $ — Cancelled / forfeited — $ — Unvested at September 30, 2017 208,822 $ 1.88

Commitments and Contingencies (

Commitments and Contingencies (Tables)	6 Months Ended
	Sep. 30, 2017
Commitments And Contingencies Disclosure [Abstract]
Future Minimum Rental Payments Required under Operating Leases that have Initial or Remaining Non-Cancelable Lease Terms in Excess of One Year	Future minimum rental payments required under operating leases that have initial or remaining non-cancelable lease terms in excess of one year as of September 30, 2017, are as follows (in thousands): Fiscal year ended March 31, 2018 794 Fiscal year ended March 31, 2019 1,465 Fiscal year ended March 31, 2020 1,073 Fiscal year ended March 31, 2021 1,104 Fiscal year ended March 31, 2022 467 Thereafter — Total 4,903

Description of Business and S16

Description of Business and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)	Oct. 25, 2016	Oct. 20, 2016	Sep. 30, 2017	Jul. 31, 2017	Apr. 30, 2017	Aug. 31, 2013	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Mar. 31, 2017	Mar. 31, 2016
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Cash and cash equivalents			$ 50,732,000				$ 50,732,000	$ 51,723,000	$ 51,723,000	$ 50,732,000	$ 51,723,000	$ 50,732,000	$ 62,751,000	$ 62,091,000
Accumulated deficit			$ (218,880,000)				$ (218,880,000)			(218,880,000)		$ (218,880,000)	$ (199,317,000)
Cash flow from operations										$ 16,802,000	14,909,000
Issuance of common stock			106,904,525				106,904,525			106,904,525		106,904,525	104,551,466
Warrants expiration date										Mar. 31, 2017
Deferred revenue			$ 654,000				$ 654,000			$ 654,000		$ 654,000	$ 582,000
Revenue recognized under grants							149,000	8,000		149,000	12,000
Cost of revenues							254,000	393,000		555,000	561,000
Dilutive effect							0	0		$ 0	$ 0
Common stock equivalents excluded from computing diluted net loss per share										15,400,000	13,200,000
NIH Research Grants Two [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue recognized under grants				$ 1,657,000
Revenue recognized under grants							149,000			$ 149,000
Private, Not-for-Profit Organization [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue recognized under grants							0	8,000		0	$ 12,000
Maximum [Member] | Private, Not-for-Profit Organization [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue recognized under grants						$ 251,700
Research and Development Services [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Deferred revenue			721,000				721,000			721,000		721,000	$ 640,000
Research and Development Services Six [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue related to research contract							0	12,500		0	25,000
Research and Development Services Four [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue related to research contract							150,000	0		150,000	0	$ 620,000
Research and Development Services Five [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue related to research contract							0	$ 332,000		0	$ 533,000
Research and Development Services Seven [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue related to research contract							18,000		$ 0	35,000
Research and Development Services Eight [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue related to research contract							9,000			19,000
Research and Development Services Ten [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue related to research contract							14,000			14,000
Research and Development Services Eleven [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue related to research contract							18,750			37,500
Non-exclusive patent license agreement annual fee					$ 75,000
Non-exclusive patent license agreement term					2 years
Proceeds from Non-exclusive patent annual license fee					$ 75,000
Research and Development Services Nine [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Revenue related to research contract			$ 50,000				$ 50,000			$ 50,000
At-The-Market Facility [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Issuance of common stock			1,538,217				1,538,217			1,538,217		1,538,217
Gross proceeds from sale of common stock shares										$ 4,000,000
Over Allotment Option [Member] | 2016 Underwriting Agreement [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Issuance of common stock	10,065,000
Secondary Offering [Member] | 2016 Underwriting Agreement [Member]
Description Of Business And Summary Of Significant Accounting Policies [Line Items]
Gross proceeds from sale of common stock shares	$ 25,700,000	$ 25,700,000

Stockholders' Equity - Schedule

Stockholders' Equity - Schedule of Stock-based Compensation Expense (Detail) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Total stock-based compensation expense	$ 2,298	$ 2,093	$ 4,350	$ 3,522
Research and development
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Total stock-based compensation expense	384	379	715	787
General and administrative
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Total stock-based compensation expense	$ 1,914	$ 1,714	$ 3,635	$ 2,735

Stockholders' Equity - Stock-ba

Stockholders' Equity - Stock-based Compensation Expense and Valuation Information - Additional Information (Detail)	6 Months Ended
	Sep. 30, 2017USD ($)
Class Of Stock [Line Items]
Total unrecognized compensation cost related to unvested stock option grants	$ 10,527,000
Employee Stock Purchase Plan [Member]
Class Of Stock [Line Items]
Total unrecognized compensation cost related, weighted average period	5 months
Unrecognized stock-based compensation expense	$ 25,000
Stock options [Member]
Class Of Stock [Line Items]
Total unrecognized compensation cost related, weighted average period	2 years 5 months 5 days
Restricted stock units (RSUs) [Member]
Class Of Stock [Line Items]
Total unrecognized compensation cost related, weighted average period	3 years 2 months 5 days
Unrecognized stock-based compensation expense	$ 7,027,000
Performance-Based Restricted Stock Units [Member]
Class Of Stock [Line Items]
Total unrecognized compensation cost related, weighted average period	2 years 1 month 28 days
Unrecognized stock-based compensation expense	$ 378,000
Restricted stock [Member]
Class Of Stock [Line Items]
Unrecognized stock-based compensation expense	$ 0

Stockholders' Equity - Fair Val

Stockholders' Equity - Fair Value of Employee Stock Options (Detail) - $ / shares	3 Months Ended		6 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Dividend yield	0.00%	0.00%	0.00%	0.00%
Volatility	70.97%	72.28%	76.85%	72.04%
Risk-free interest rate	1.78%	1.07%	1.81%	1.10%
Expected life of options	6 years	6 years	6 years	6 years
Weighted average grant date fair value	$ 1.25	$ 2.57	$ 1.73	$ 2.44

Stockholders' Equity - Fair V20

Stockholders' Equity - Fair Value of Employee Stock Purchase Plan (Detail) - $ / shares	3 Months Ended		6 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Dividend yield	0.00%	0.00%	0.00%	0.00%
Volatility	70.97%	72.28%	76.85%	72.04%
Risk-free interest rate	1.78%	1.07%	1.81%	1.10%
Expected term	6 years	6 years	6 years	6 years
Weighted average grant date fair value	$ 1.25	$ 2.57	$ 1.73	$ 2.44
2016 Employee Stock Purchase Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Dividend yield	0.00%	0.00%	0.00%	0.00%
Volatility		72.89%		72.89%
Volatility, Minimum	43.03%		43.03%
Volatility, Maximum	74.70%		74.70%
Risk-free interest rate		0.47%		0.47%
Risk-free interest rate, Minimum	0.79%		0.79%
Risk-free interest rate, Maximum	1.10%		1.10%
Expected term	6 months	6 months	6 months	6 months
Weighted average grant date fair value		$ 1.22		$ 1.22
2016 Employee Stock Purchase Plan [Member] | Minimum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Weighted average grant date fair value	$ 0.52		$ 0.52
2016 Employee Stock Purchase Plan [Member] | Maximum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Weighted average grant date fair value	$ 1.04		$ 1.04

Stockholders' Equity - Preferre

Stockholders' Equity - Preferred Stock - Additional Information (Detail)	Sep. 30, 2017shares
Equity [Abstract]
Preferred stock, shares authorized	25,000,000
Preferred stock, shares outstanding	0

Stockholders' Equity - Common S

Stockholders' Equity - Common Stock - Additional Information (Detail) - USD ($)	Oct. 25, 2016	Oct. 20, 2016	Jul. 20, 2016	Jun. 23, 2015	Jul. 17, 2013	Dec. 31, 2014	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Apr. 24, 2017	Mar. 31, 2017	Aug. 31, 2015	Feb. 27, 2015	Aug. 31, 2013	Jan. 31, 2012	May 31, 2008
Class Of Stock [Line Items]
Common stock reserved for future issuance							18,879,471		18,879,471		18,879,471
Issuance of common stock from stock options exercises, net, Shares							500,000	206,266	500,000	206,266
Issuance of common stock							106,904,525		106,904,525		106,904,525		104,551,466
Issuance of common stock from warrant exercises, net, Shares							0	123,104	0	123,104
Warrants exercised							0	160,000	0	160,000
Issuances of common stock from stock option exercises, Shares							500,000	206,266	500,000	206,266
Equity Offering Sales Agreement [Member]
Class Of Stock [Line Items]
Common stock reserved for future issuance			26,600,000
Equity sales agreement expiration date			Mar. 17, 2018
Issuance of common stock from stock options exercises, net, Shares							398,728	997,181	1,538,217	997,181
Value of shares sold under equity distribution agreement							$ 1,000,000	$ 4,500,000	$ 4,000,000	$ 4,500,000	$ 14,800,000
Issuance of common stock							3,535,398		3,535,398		3,535,398
Additional common stocks under shelf registration							$ 17,800,000		$ 17,800,000		$ 17,800,000
Maximum [Member] | Equity Distribution Agreement [Member]
Class Of Stock [Line Items]
Number of shares to be offered and sold in equity distribution agreement						30,000,000
IPO [Member]
Class Of Stock [Line Items]
Securities authorized for offer and sale, amount					$ 100,000,000										$ 190,000,000
Stock securities distribution plan termination year					2,016
Secondary Offering [Member] | 2015 Underwriting Agreement [Member]
Class Of Stock [Line Items]
Issuance of common stock from stock options exercises, net, Shares				10,838,750
Offering price per share				$ 4.25
Gross proceeds from sale of common stock shares				$ 43,100,000
Secondary Offering [Member] | 2016 Underwriting Agreement [Member]
Class Of Stock [Line Items]
Offering price per share		$ 2.75
Gross proceeds from sale of common stock shares	$ 25,700,000	$ 25,700,000
Over Allotment Option [Member] | 2015 Underwriting Agreement [Member]
Class Of Stock [Line Items]
Sale of stock price per share net of fees				$ 3.995
Over Allotment Option [Member] | 2016 Underwriting Agreement [Member]
Class Of Stock [Line Items]
Issuance of common stock	10,065,000
Sale of stock price per share net of fees		$ 2.585
Equity Incentive Plan 2008 [Member]
Class Of Stock [Line Items]
Common shares authorized to be issued																		1,521,584
Termination date of equity incentive plan									Jul. 1, 2018
Shares issued during the year									0
Equity Incentive Plan 2012 [Member]
Class Of Stock [Line Items]
Common shares authorized to be issued														6,000,000		5,000,000	6,553,986
Shares available for issuance							2,117,682		2,117,682		2,117,682			17,553,986
Termination period of Equity Incentive Plan									10 years
Inducement Award Agreements [Member]
Class Of Stock [Line Items]
Common shares authorized to be issued												2,297,034

Stockholders' Equity - Restrict

Stockholders' Equity - Restricted Stock Awards, Restricted Stock Units and Performance-Based Restricted Stock Units - Additional Information (Detail)	Aug. 23, 2017USD ($)Trancheshares	Sep. 30, 2017Trancheshares	Sep. 30, 2016shares	Sep. 30, 2017Trancheshares	Sep. 30, 2016shares	Apr. 24, 2017shares	Mar. 31, 2017shares
Restricted stock [Member]
Class Of Stock [Line Items]
Restricted stock surrendered		0	0	0	2,259
Restricted stock awards vested during the period		0	0	0	6,250
Stock option granted with immediate vesting		0	0	0	2,259
Restricted stock units (RSUs) [Member]
Class Of Stock [Line Items]
Restricted stock awards vested during the period				263,594
Restricted stock awards granted		7,000		1,869,078
Award vesting conditions		Vesting generally occurs (i) on the one-year anniversary of the grant date, (ii) quarterly over a three-year period, (iii) quarterly over a four-year period, (iv) over a four-year period, with 25% vesting on the one-year anniversary of the vesting commencement date and the remainder vesting ratably on a quarterly basis over the next twelve quarters, or (v) over a three-year period with 50% vesting on the two-year anniversary of the vesting commencement date and 50% vesting on the three-year anniversary of the vesting commencement date.
Period for vesting schedule over start date		4 years
Awards granted remainder vesting period ratably on a quarterly basis		36 months
Award vesting percentage on the two-year anniversary		50.00%
Award vesting percentage on the three-year anniversary		50.00%
Number of shares allocated		2,628,674		2,628,674			1,178,114
Restricted stock units (RSUs) [Member] | Yearly Vesting [Member]
Class Of Stock [Line Items]
Award vesting percentage		25.00%
Inducement Award Performance-Based Restricted Stock Units [Member]
Class Of Stock [Line Items]
Award vesting percentage				100.00%
Number of tranches | Tranche	5
Number of tranches vested | Tranche		0		0
Grant date fair values of tranches | $	$ 393,000
Stock units vesting and expected to vest		83,530		83,530
Inducement Award Performance-Based Restricted Stock Units [Member] | Maximum [Member]
Class Of Stock [Line Items]
Number of shares allocated	208,822
Inducement Award Performance-Based Restricted Stock Units [Member] | CEO [Member]
Class Of Stock [Line Items]
Number of shares allocated						208,822
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche One [Member]
Class Of Stock [Line Items]
Award vesting percentage	20.00%
Stock units vesting year	2,018
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche One [Member] | Minimum [Member]
Class Of Stock [Line Items]
Award vesting percentage	0.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche One [Member] | Maximum [Member]
Class Of Stock [Line Items]
Award vesting percentage	120.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche Two [Member]
Class Of Stock [Line Items]
Award vesting percentage	20.00%
Stock units vesting year	2,019
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche Two [Member] | Minimum [Member]
Class Of Stock [Line Items]
Award vesting percentage	0.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche Two [Member] | Maximum [Member]
Class Of Stock [Line Items]
Award vesting percentage	120.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche Three [Member]
Class Of Stock [Line Items]
Award vesting percentage	20.00%
Stock units vesting year	2,020
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche Three [Member] | Minimum [Member]
Class Of Stock [Line Items]
Award vesting percentage	0.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share-based Compensation Award, Tranche Three [Member] | Maximum [Member]
Class Of Stock [Line Items]
Award vesting percentage	120.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share Based Compensation Award Tranche Four [Member]
Class Of Stock [Line Items]
Award vesting percentage	20.00%
Stock units vesting year	2,021
Inducement Award Performance-Based Restricted Stock Units [Member] | Share Based Compensation Award Tranche Four [Member] | Minimum [Member]
Class Of Stock [Line Items]
Award vesting percentage	0.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share Based Compensation Award Tranche Four [Member] | Maximum [Member]
Class Of Stock [Line Items]
Award vesting percentage	120.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share Based Compensation Award Tranche Five [Member]
Class Of Stock [Line Items]
Award vesting percentage	20.00%
Stock units vesting year	2,020
Inducement Award Performance-Based Restricted Stock Units [Member] | Share Based Compensation Award Tranche Five [Member] | Minimum [Member]
Class Of Stock [Line Items]
Award vesting percentage	0.00%
Inducement Award Performance-Based Restricted Stock Units [Member] | Share Based Compensation Award Tranche Five [Member] | Maximum [Member]
Class Of Stock [Line Items]
Award vesting percentage	120.00%

Stockholders' Equity - Summary

Stockholders' Equity - Summary of Company's Restricted Stock Unit Activity and Performance Based Restricted Stock Unit Activity (Detail) - $ / shares	3 Months Ended	6 Months Ended
	Sep. 30, 2017	Sep. 30, 2017
Restricted stock units (RSUs) [Member]
Class Of Stock [Line Items]
Beginning balance, Unvested, Number of Shares		1,178,114
Granted, Number of Shares	7,000	1,869,078
Vested, Number of Shares		(263,594)
Canceled / forfeited, Number of Shares		(154,924)
Ending balance, Unvested, Number of Shares	2,628,674	2,628,674
Beginning balance, Unvested, Weighted Average Price		$ 3.57
Granted, Weighted Average Price		2.66
Vested, Weighted Average Price		3.45
Canceled / forfeited, Weighted Average Price		3.04
Ending balance, Unvested, Weighted Average Price	$ 2.96	$ 2.96
Performance-Based Restricted Stock Units [Member]
Class Of Stock [Line Items]
Beginning balance, Unvested, Number of Shares		0
Granted, Number of Shares		208,822
Vested, Number of Shares		0
Canceled / forfeited, Number of Shares		0
Ending balance, Unvested, Number of Shares	208,822	208,822
Beginning balance, Unvested, Weighted Average Price		$ 0
Granted, Weighted Average Price		1.88
Vested, Weighted Average Price		0
Canceled / forfeited, Weighted Average Price		0
Ending balance, Unvested, Weighted Average Price	$ 1.88	$ 1.88

Stockholders' Equity - Stock Op

Stockholders' Equity - Stock Options and Employee Stock Purchase Plan - Additional Information (Detail) - USD ($)	Apr. 24, 2017	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Class Of Stock [Line Items]
Issuances of common stock from stock option exercises, Shares		500,000	206,266	500,000	206,266
Weighted-average remaining contractual term of options exercisable				6 years
Weighted-average remaining contractual term of options outstanding				6 years
Number of common stock shares approved under ESPP		18,879,471		18,879,471
Expected life of options		6 years	6 years	6 years	6 years
2012 Plan [Member]
Class Of Stock [Line Items]
Issuances of common stock from stock option exercises, Shares		260,000	1,386,500	2,366,812	1,803,140
Remaining options vest		36 months
Inducement Award Agreements [Member] | CEO [Member]
Class Of Stock [Line Items]
Stock options granted	2,088,212
2016 Employee Stock Purchase Plan [Member]
Class Of Stock [Line Items]
Number of common stock shares approved under ESPP		1,500,000		1,500,000
Employee subscription rate		15.00%		15.00%
Number of shares per employee				10,000
Fair market value at discount				85.00%
Purchase period				6 months
Initial offering period				2016-09
Description of plan				Shares under the ESPP are purchased at 85 percent of the fair market value at the lower of (i) the closing price on the first trading day of the six-month purchase period or (ii) the closing price on the last trading day of the six-month purchase period.
Expected life of options		6 months	6 months	6 months	6 months
Shares available for issuance		1,372,960		1,372,960
2016 Employee Stock Purchase Plan [Member] | Maximum [Member]
Class Of Stock [Line Items]
Compensation amount per employee				$ 25,000
Stock options [Member] | 2012 Plan [Member]
Class Of Stock [Line Items]
Award vesting conditions		stock options generally vest (i) on the one-year anniversary of the grant date, (ii) quarterly over a three-year period, or (iii) over a four-year period with a quarter vesting on either the one year anniversary of employment or the one year anniversary of the vesting commencement date
Stock options [Member] | Inducement Award Agreements [Member]
Class Of Stock [Line Items]
Number of common stock shares approved under ESPP		2,088,212		2,088,212
Stock options [Member] | Inducement Award Agreements [Member] | CEO [Member]
Class Of Stock [Line Items]
Award vesting conditions		These stock options vest over a four-year period with a quarter vesting on either the one year anniversary of employment or the one year anniversary of the vesting commencement date.
Period for vesting schedule over start date	4 years
Stock options [Member] | 2016 Employee Stock Purchase Plan [Member]
Class Of Stock [Line Items]
Number of common stock shares approved under ESPP		1,372,960		1,372,960

Stockholders' Equity - Summar26

Stockholders' Equity - Summary of Stock Option Activity (Detail) - USD ($)	3 Months Ended		6 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Options Outstanding, Beginning balance			10,956,201
Granted, Options Outstanding			2,366,812
Cancelled / forfeited, Options Outstanding			(493,050)
Exercised, Options Outstanding	(500,000)	(206,266)	(500,000)	(206,266)
Options Outstanding, Ending balance	12,329,963		12,329,963
Vested and Exercisable, Options Outstanding	7,265,871		7,265,871
Weighted-Average Exercise Price, Options Beginning balance			$ 4.63
Options granted, Weighted-Average Exercise Price			2.65
Options cancelled / forfeited, Weighted-Average Exercise Price			4.41
Options exercised, Weighted-Average Exercise Price			1.65
Weighted-Average Exercise Price, Options Ending balance	$ 4.38		4.38
Vested and Exercisable, Weighted-Average Exercise Price	$ 4.92		$ 4.92
Aggregate Intrinsic Value, Options Beginning balance			$ 4,876,437
Options Exercised, Aggregate Intrinsic Value			235,000
Aggregate Intrinsic Value, Options	$ 1,812,776		1,812,776
Vested and Exercisable, Aggregate Intrinsic Value	$ 1,723,601		$ 1,723,601

Stockholders' Equity - Warrants

Stockholders' Equity - Warrants - Additional Information (Detail) - $ / shares	3 Months Ended		6 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Class Of Stock [Line Items]
Weighted-average remaining contractual term of options exercisable			6 years
Minimum [Member]
Class Of Stock [Line Items]
Warrants exercisable price, per share	$ 2.28		$ 2.28
Maximum [Member]
Class Of Stock [Line Items]
Warrants exercisable price, per share	$ 7.62		$ 7.62
Warrants [Member]
Class Of Stock [Line Items]
Number of warrants exercised	0		0
Number of warrant exercised through cashless		160,000		160,000
Cashless exercise in exchange for issuance of common stock		123,104		123,104
Weighted-average remaining contractual term of options exercisable			1 year 4 months 10 days

Stockholders' Equity - Summar28

Stockholders' Equity - Summary of Warrant Activity (Detail) - $ / shares	3 Months Ended		6 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Options Outstanding, Beginning balance			10,956,201
Granted, Options Outstanding			2,366,812
Exercised, Options Outstanding	(500,000)	(206,266)	(500,000)	(206,266)
Options Outstanding, Ending balance	12,329,963		12,329,963
Weighted-Average Exercise Price, Options Beginning balance			$ 4.63
Granted, Weighted-Average Exercise Price			2.65
Exercised, Weighted-Average Exercise Price			1.65
Weighted-Average Exercise Price, Options Ending balance	$ 4.38		$ 4.38
Warrants [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Options Outstanding, Beginning balance			221,370
Granted, Options Outstanding			0
Exercised, Options Outstanding			0
Cancelled, Options Outstanding			0
Options Outstanding, Ending balance	221,370		221,370
Weighted-Average Exercise Price, Options Beginning balance			$ 7.16
Granted, Weighted-Average Exercise Price			0
Exercised, Weighted-Average Exercise Price			0
Cancelled, Weighted-Average Exercise Price			0
Weighted-Average Exercise Price, Options Ending balance	$ 7.16		$ 7.16

Stockholders' Equity - Common29

Stockholders' Equity - Common Stock Reserved for Future Issuance (Detail)	Sep. 30, 2017shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	18,879,471
2016 Employee Stock Purchase Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	1,500,000
Warrants [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	221,370
Stock options [Member] | Equity Incentive Plan 2008 [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	622,192
Stock options [Member] | Equity Incentive Plan 2012 [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	11,737,241
Stock options [Member] | 2016 Employee Stock Purchase Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	1,372,960
Stock options [Member] | Inducement Award Agreements [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	2,088,212
Restricted stock units (RSUs) [Member] | Equity Incentive Plan 2012 [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	2,628,674
Restricted stock units (RSUs) [Member] | Inducement Award Agreements [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserved for future issuance	208,822

Commitments and Contingencies -

Commitments and Contingencies - Additional Information (Detail)	Dec. 28, 2015USD ($)ft²	Jan. 09, 2015USD ($)ft²	Sep. 30, 2017USD ($)Lease	Sep. 30, 2016USD ($)	Sep. 30, 2017USD ($)ft²Lease	Sep. 30, 2016USD ($)	Sep. 30, 2017USD ($)Lease
Commitments And Contingencies [Line Items]
Number of non-cancelable leases | Lease			2		2		2
Rent expense per month					$ 120,000
Base rent escalators		3.00%	3.00%		3.00%		3.00%
Office space under lease agreement | ft²					45,580
Area of leased office space | ft²	12,088	5,803
Lease term		36 months
Lease rental period start date	Feb. 1, 2016	Feb. 1, 2015
Lease rental period end date	Jan. 31, 2017	Jan. 31, 2018
Base rent under the lease	$ 15,000	$ 12,000
Leasehold improvements							$ 518,000
Rent expense			$ 365,000	$ 302,000	$ 731,000	$ 605,000
Lease Term For Remainder of Rentable Square Footage [Member]
Commitments And Contingencies [Line Items]
Lease expiration date					Sep. 1, 2021
Lease option termination description					option to terminate this lease on or after September 1, 2019
Lease Term For 14,685 of Total Rentable Square Footage [Member]
Commitments And Contingencies [Line Items]
Office space under lease agreement | ft²					14,685
Lease expiration date					Dec. 15, 2018

Commitments and Contingencies31

Commitments and Contingencies - Future Minimum Rental Payments Required under Operating Leases that have Initial or Remaining Non-Cancelable Lease Terms in Excess of One Year (Detail) $ in Thousands	Sep. 30, 2017USD ($)
Commitments And Contingencies Disclosure [Abstract]
Fiscal year ended March 31, 2018	$ 794
Fiscal year ended March 31, 2019	1,465
Fiscal year ended March 31, 2020	1,073
Fiscal year ended March 31, 2021	1,104
Fiscal year ended March 31, 2022	467
Thereafter	0
Total	$ 4,903

Related Parties - Additional In

Related Parties - Additional Information (Detail)	3 Months Ended		6 Months Ended	12 Months Ended
	Dec. 31, 2017USD ($)	Sep. 30, 2017USD ($)Agreement	Sep. 30, 2017USD ($)Agreement	Mar. 31, 2018USD ($)
Related Party Transaction [Line Items]
Number of related parties agreement entered | Agreement		2	2
Cirius Tx, Inc., [Member]
Related Party Transaction [Line Items]
Amount of transactions with related party for providing services		$ 50,000	$ 50,000
Cirius Tx, Inc., [Member] | Scenario, Forecast [Member]
Related Party Transaction [Line Items]
Amount of transactions with related party for providing services	$ 44,000
Viscient Biosciences [Member]
Related Party Transaction [Line Items]
Amount of transactions with related party for providing services		$ 0	$ 0
Viscient Biosciences [Member] | Scenario, Forecast [Member]
Related Party Transaction [Line Items]
Amount of transactions with related party for providing services				$ 287,000

Subsequent Events - Additional

Subsequent Events - Additional Information (Detail) $ in Millions	Oct. 04, 2017Position	Dec. 31, 2017USD ($)
Scenario, Forecast [Member] | Employee Severance and Benefits Costs [Member]
Subsequent Event [Line Items]
Restructuring charge | $		$ 0.9
Subsequent Event [Member]
Subsequent Event [Line Items]
Number of positions reduced | Position	15
Percentage of overall workforce reduced	13.00%