Document and Entity Information
Document and Entity Information - shares | 6 Months Ended | |
Sep. 30, 2022 | Nov. 01, 2022 | |
Cover [Abstract] | ||
Document Type | 10-Q | |
Amendment Flag | false | |
Document Period End Date | Sep. 30, 2022 | |
Document Fiscal Year Focus | 2023 | |
Document Fiscal Period Focus | Q2 | |
Trading Symbol | ONVO | |
Entity Registrant Name | Organovo Holdings, Inc. | |
Entity Central Index Key | 0001497253 | |
Current Fiscal Year End Date | --03-31 | |
Entity Filer Category | Non-accelerated Filer | |
Entity Shell Company | false | |
Entity Small Business | true | |
Entity Emerging Growth Company | false | |
Entity Common Stock, Shares Outstanding | 8,713,268 | |
Entity File Number | 001-35996 | |
Entity Current Reporting Status | Yes | |
Entity Tax Identification Number | 27-1488943 | |
Entity Address, Address Line One | 11555 Sorrento Valley Rd | |
Entity Address, Address Line Two | Suite 100 | |
Entity Address, City or Town | San Diego | |
Entity Address, State or Province | CA | |
Entity Address, Postal Zip Code | 92121 | |
City Area Code | 858 | |
Local Phone Number | 224-1000 | |
Entity Interactive Data Current | Yes | |
Title of 12(b) Security | Common Stock, $0.001 par value | |
Security Exchange Name | NASDAQ | |
Entity Incorporation, State or Country Code | DE | |
Document Quarterly Report | true | |
Document Transition Report | false |
Condensed Consolidated Balance
Condensed Consolidated Balance Sheets - USD ($) $ in Thousands | Sep. 30, 2022 | Mar. 31, 2022 |
Current Assets | ||
Cash and cash equivalents | $ 13,265 | $ 28,675 |
Short-term investments | 9,955 | 0 |
Investment in equity securities | 618 | 0 |
Prepaid expenses and other current assets | 519 | 858 |
Total current assets | 24,357 | 29,533 |
Fixed assets, net | 758 | 662 |
Restricted cash | 143 | 143 |
Operating lease right-of-use assets | 1,958 | 2,153 |
Prepaid expenses and other assets, net | 694 | 805 |
Total assets | 27,910 | 33,296 |
Current Liabilities | ||
Accounts payable | 441 | 415 |
Accrued expenses | 462 | 489 |
Operating lease liability, current portion | 486 | 479 |
Total current liabilities | 1,389 | 1,383 |
Operating lease liability, net of current portion | 1,515 | 1,704 |
Total liabilities | 2,904 | 3,087 |
Stockholders’ Equity | ||
Common stock, $0.001 par value; 200,000,000 shares authorized, 8,713,268 and 8,710,627 shares issued and outstanding at September 30, 2022 and March 31, 2022, respectively | 9 | 9 |
Additional paid-in capital | 339,273 | 337,940 |
Accumulated deficit | (314,275) | (307,739) |
Treasury stock, 46 shares at cost | (1) | (1) |
Total stockholders’ equity | 25,006 | 30,209 |
Total Liabilities and Stockholders’ Equity | $ 27,910 | $ 33,296 |
Condensed Consolidated Balanc_2
Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares | Sep. 30, 2022 | Mar. 31, 2022 |
Statement Of Financial Position [Abstract] | ||
Common stock, par value | $ 0.001 | $ 0.001 |
Common stock, shares authorized | 200,000,000 | 200,000,000 |
Common stock, shares issued | 8,713,268 | 8,710,627 |
Common stock, shares outstanding | 8,713,268 | 8,710,627 |
Treasury stock, shares | 46 | 46 |
Unaudited Condensed Consolidate
Unaudited Condensed Consolidated Statements of Operations and Other Comprehensive Loss - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | |
Revenues | ||||
Total Revenues | $ 77 | $ 0 | $ 77 | $ 0 |
Revenue From Contract With Customer Product And Service [Extensible List] | us-gaap:RoyaltyMember | us-gaap:RoyaltyMember | us-gaap:RoyaltyMember | us-gaap:RoyaltyMember |
Research and development expenses | $ 1,231 | $ 679 | $ 2,251 | $ 1,259 |
Selling, general and administrative expenses | 2,200 | 2,828 | 4,419 | 4,807 |
Total costs and expenses | 3,431 | 3,507 | 6,670 | 6,066 |
Loss from Operations | (3,354) | (3,507) | (6,593) | (6,066) |
Other Income (Expense) | ||||
Loss on investment in equity securities | (70) | 0 | (75) | 0 |
Interest income | 103 | 2 | 134 | 4 |
Other income | 0 | 0 | 0 | 25 |
Total Other Income | 33 | 2 | 59 | 29 |
Income Tax Expense | 0 | 0 | (2) | 0 |
Net Loss | $ (3,321) | $ (3,505) | $ (6,536) | $ (6,037) |
Net loss per common share basic | $ (0.38) | $ (0.40) | $ (0.75) | $ (0.69) |
Net loss per common share diluted | $ (0.38) | $ (0.40) | $ (0.75) | $ (0.69) |
Weighted average shares used in computing net loss per common share basic | 8,712,284 | 8,705,327 | 8,711,630 | 8,701,029 |
Weighted average shares used in computing net loss per common share diluted | 8,712,284 | 8,705,327 | 8,711,630 | 8,701,029 |
Comprehensive Loss: | ||||
Net loss | $ (3,321) | $ (3,505) | $ (6,536) | $ (6,037) |
Comprehensive loss | $ (3,321) | $ (3,505) | $ (6,536) | $ (6,037) |
Unaudited Condensed Consolida_2
Unaudited Condensed Consolidated Statements of Stockholders' Equity - USD ($) shares in Thousands, $ in Thousands | Total | Common Stock [Member] | Additional Paid-in Capital [Member] | Treasury Stock [Member] | Accumulated Deficit [Member] |
Beginning balance at Mar. 31, 2021 | $ 39,196 | $ 9 | $ 335,479 | $ (1) | $ (296,291) |
Beginning balance, Shares at Mar. 31, 2021 | 8,671 | 0 | |||
Issuance of common stock from public offering, net | 251 | $ 0 | 251 | $ 0 | 0 |
Issuance of common stock from public offering, Shares | 27 | ||||
Stock-based compensation expense | 415 | $ 0 | 415 | 0 | 0 |
Net loss | (2,532) | 0 | 0 | 0 | (2,532) |
Ending balance at Jun. 30, 2021 | 37,330 | $ 9 | 336,145 | $ (1) | (298,823) |
Ending balance, Shares at Jun. 30, 2021 | 8,698 | 0 | |||
Beginning balance at Mar. 31, 2021 | 39,196 | $ 9 | 335,479 | $ (1) | (296,291) |
Beginning balance, Shares at Mar. 31, 2021 | 8,671 | 0 | |||
Net loss | (6,037) | ||||
Ending balance at Sep. 30, 2021 | 34,206 | $ 9 | 336,526 | $ (1) | (302,328) |
Ending balance, Shares at Sep. 30, 2021 | 8,705 | 0 | |||
Beginning balance at Jun. 30, 2021 | 37,330 | $ 9 | 336,145 | $ (1) | (298,823) |
Beginning balance, Shares at Jun. 30, 2021 | 8,698 | 0 | |||
Issuance of common stock under employee and director stock option, RSU, and purchase plans | (45) | $ 0 | (45) | $ 0 | 0 |
Issuance of common stock under employee and director stock option, restricted stock units, and purchase plans, Shares | 7 | ||||
Stock-based compensation expense | 426 | $ 0 | 426 | 0 | 0 |
Net loss | (3,505) | 0 | 0 | 0 | (3,505) |
Ending balance at Sep. 30, 2021 | 34,206 | $ 9 | 336,526 | $ (1) | (302,328) |
Ending balance, Shares at Sep. 30, 2021 | 8,705 | 0 | |||
Beginning balance at Mar. 31, 2022 | 30,209 | $ 9 | 337,940 | $ (1) | (307,739) |
Beginning balance, Shares at Mar. 31, 2022 | 8,711 | 0 | |||
Issuance of common stock under employee and director stock option, RSU, and purchase plans | 0 | $ 0 | 0 | $ 0 | 0 |
Issuance of common stock under employee and director stock option, restricted stock units, and purchase plans, Shares | 1 | ||||
Stock-based compensation expense | 660 | $ 0 | 660 | 0 | 0 |
Net loss | (3,215) | 0 | 0 | 0 | (3,215) |
Ending balance at Jun. 30, 2022 | 27,654 | $ 9 | 338,600 | $ (1) | (310,954) |
Ending balance, Shares at Jun. 30, 2022 | 8,712 | 0 | |||
Beginning balance at Mar. 31, 2022 | 30,209 | $ 9 | 337,940 | $ (1) | (307,739) |
Beginning balance, Shares at Mar. 31, 2022 | 8,711 | 0 | |||
Net loss | (6,536) | ||||
Ending balance at Sep. 30, 2022 | 25,006 | $ 9 | 339,273 | $ (1) | (314,275) |
Ending balance, Shares at Sep. 30, 2022 | 8,713 | 0 | |||
Beginning balance at Jun. 30, 2022 | 27,654 | $ 9 | 338,600 | $ (1) | (310,954) |
Beginning balance, Shares at Jun. 30, 2022 | 8,712 | 0 | |||
Issuance of common stock under employee and director stock option, RSU, and purchase plans | 0 | $ 0 | 0 | $ 0 | 0 |
Issuance of common stock under employee and director stock option, restricted stock units, and purchase plans, Shares | 1 | ||||
Stock-based compensation expense | 673 | $ 0 | 673 | 0 | 0 |
Net loss | (3,321) | 0 | 0 | 0 | (3,321) |
Ending balance at Sep. 30, 2022 | $ 25,006 | $ 9 | $ 339,273 | $ (1) | $ (314,275) |
Ending balance, Shares at Sep. 30, 2022 | 8,713 | 0 |
Unaudited Condensed Consolida_3
Unaudited Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | |
Cash Flows From Operating Activities | ||||
Net loss | $ (3,321) | $ (3,505) | $ (6,536) | $ (6,037) |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||
Loss on investment in equity securities | 70 | 0 | 75 | 0 |
Accretion on short-term investments | (62) | 0 | ||
Depreciation and amortization | 104 | 59 | ||
Stock-based compensation | 673 | 426 | 1,333 | 841 |
Increase (decrease) in cash resulting from changes in: | ||||
Prepaid expenses and other assets | 443 | 627 | ||
Accounts payable | 26 | 677 | ||
Accrued expenses | (27) | 277 | ||
Operating lease right-of-use assets and liabilities, net | 13 | 0 | ||
Net cash used in operating activities | (4,631) | (3,556) | ||
Cash Flows From Investing Activities | ||||
Purchases of fixed assets | (193) | (223) | ||
Purchases of short-term investments | (9,893) | 0 | ||
Purchases of equity securities | (1,061) | 0 | ||
Sales of equity securities | 368 | 0 | ||
Net cash used in investing activities | (10,779) | (223) | ||
Cash Flows From Financing Activities | ||||
Proceeds from issuance of common stock, net | 0 | 251 | ||
Employee taxes paid related to net share settlement of equity awards | 0 | (45) | ||
Net cash provided by financing activities | 0 | 206 | ||
Net decrease in cash, cash equivalents, and restricted cash | (15,410) | (3,573) | ||
Cash, cash equivalents, and restricted cash at beginning of period | 13,408 | 33,902 | 28,818 | 37,475 |
Cash, cash equivalents, and restricted cash at end of period | 13,408 | 33,902 | 13,408 | 33,902 |
Reconciliation of cash, cash equivalents, and restricted cash to the condensed consolidated balance sheets | ||||
Cash and cash equivalents | 13,265 | 33,791 | 13,265 | 33,791 |
Restricted cash | 143 | 111 | 143 | 111 |
Cash, cash equivalents, and restricted cash at end of period | $ 13,408 | $ 33,902 | 13,408 | 33,902 |
Supplemental Disclosure of Cash Flow Information: | ||||
Income taxes paid | $ (2) | $ 0 |
Description of Business
Description of Business | 6 Months Ended |
Sep. 30, 2022 | |
Organization Consolidation And Presentation Of Financial Statements [Abstract] | |
Description of Business | Note Nature of Operations Organovo Holdings, Inc. (“Organovo Holdings,” “Organovo,” and the “Company”) is an early-stage biotechnology company that focuses on building high fidelity, 3D tissues that recapitulate key aspects of human disease. The Company uses these models to identify gene targets responsible for driving the disease and intends to initiate drug discovery programs around these validated targets. The Company is initially focusing on the intestine and has ongoing 3D tissue development efforts in ulcerative colitis (“UC”) and Crohn’s disease (“CD”). Recently, the Company announced that it has successfully advanced its first inflammatory bowel disease (“IBD”) model to the next step of target discovery and validation for CD. The Company intends to add additional tissues/diseases/targets to its portfolio over time. In line with these plans, the Company is building upon both its external and in house scientific expertise, which will be essential to its drug development effort. The Company uses its proprietary technology to build functional 3D human tissues that mimic key aspects of native human tissue composition, architecture, function and disease. Organovo’s advances include cell type-specific compartments, prevalent intercellular tight junctions, and the formation of microvascular structures. Management believes these attributes can enable critical complex, multicellular disease models that can be used to develop clinically effective drugs across multiple therapeutic areas. The Company’s NovoGen Bioprinters ® The Company believes that the use of its bioprinting platform as well as complementary 3D technologies will allow it to develop an understanding of disease biology that leads to validated novel drug targets and therapeutics to those targets to treat disease. The majority of the Company’s current focus is in IBD, including CD and UC. The Company is creating high fidelity disease models, leveraging its prior work including the work found in its peer-reviewed publication on bioprinted intestinal tissues ( Madden et al. Bioprinted 3D Primary Human Intestinal Tissues Model Aspects of Native Physiology and ADME/Tox Functions. iScience. 2018 Apr 27;2:156-167. doi: 10.1016/j.isci.2018.03.015.) The Company’s current understanding of intestinal tissue models and IBD disease models leads it to believe that it can create models that provide greater insight into the biology of these diseases than are generally currently available. Using these disease models, the Company has identified and validated novel therapeutic targets and is actively focused on developing novel small molecule, antibody, or other therapeutic drug candidates to treat the disease, and advance these novel drug candidates towards an Investigational New Drug (“IND”) filing and potential future clinical trials. The Company expects to broaden its work into additional therapeutic areas over time and is currently exploring specific tissues for development. In the Company’s work to identify the areas of interest, it evaluates areas that might be better served with 3D disease models than currently available models as well as the potential commercial opportunity. Except where specifically noted or the context otherwise requires, references to “Organovo Holdings”, “the Company”, and “Organovo” in these notes to the consolidated financial statements refers to Organovo Holdings, Inc. and its wholly owned subsidiaries, Organovo, Inc., and Opal Merger Sub, Inc. COVID-19 Global health concerns relating to the COVID-19 pandemic continue to weigh on the macroeconomic environment, and the pandemic has significantly increased economic volatility and uncertainty. The extent to which the coronavirus impacts the Company’s operations will depend on future developments, which are highly uncertain and cannot be predicted with confidence, including the rise of vaccine-resistant variants, the duration of the outbreak, and any travel bans and restrictions or other limitations that may be imposed in the future |
Summary of Significant Accounti
Summary of Significant Accounting Policies | 6 Months Ended |
Sep. 30, 2022 | |
Accounting Policies [Abstract] | |
Summary of Significant Accounting Policies | Note 2. Summary of Significant Accounting Policies Basis of Presentation and Principles of Consolidation The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (“GAAP”) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not necessarily include all information and notes required by GAAP for complete financial statements. The condensed consolidated balance sheet at March 31, 2022 is derived from the Company’s audited consolidated balance sheet at that date. The unaudited condensed consolidated financial statements include the accounts of Organovo and its wholly owned subsidiaries. All material intercompany accounts and transactions have been eliminated in consolidation. In the opinion of management, the unaudited financial information for the interim periods presented reflects all adjustments, which are only normal and recurring, necessary for a fair statement of the Company’s financial position, results of operations, stockholders’ equity and cash flows. These unaudited condensed consolidated financial statements should be read in conjunction with the audited financial statements and notes included in the Company’s Annual Report on Form 10-K for the year ended March 31, 2022, as filed with the Securities and Exchange Commission (“SEC”). Operating results for any interim period are not necessarily indicative of the operating results for any other interim period or the Company’s full fiscal year ending March 31, 2023 (see “ Note 1. Description of Business” Liquidity As of September 30, 2022, the Company had cash and cash equivalents of approximately $13.3 million, short-term investments of $10.0 million, restricted cash of approximately $0.1 million and an accumulated deficit of approximately $314.3 million. The restricted cash was pledged as collateral for a letter of credit that the Company is required to maintain as a security deposit under the terms of the lease agreement for its facilities. The Company also had negative cash flows from operations of approximately $4.6 million during the six months ended September 30, 2022. Through September 30, 2022, the Company has financed its operations primarily through the sale of convertible notes, warrants, the private placement of equity securities, the sale of common stock through public and at-the-market (“ATM”) offerings, and through revenue derived from product and research service-based agreements, collaborative agreements, licenses, and grants. During the three and six months ended September 30, 2022, the Company issued zero shares of its common stock through its ATM facility. The Company believes its cash and cash equivalents on hand will be sufficient to meet its financial obligations for at least the next 12 months of operations. As the Company continues to focus its efforts on drug discovery and development, it will need to raise additional capital to implement this business plan. The Company cannot predict with certainty the exact amount or timing for any future capital raises. If required, the Company may seek to raise additional capital through debt or equity financings, or through some other financing arrangement. However, the Company cannot be sure that additional financing will be available if and when needed, or that, if available, it can obtain financing on terms favorable to its stockholders. Any failure to obtain financing when required will have a material adverse effect on the Company’s business, operating results, financial condition and ability to continue as a going concern. Use of Estimates The preparation of the financial statements in conformity with accounting principles generally accepted in the United States requires management to make estimates and assumptions that affect certain reported amounts and disclosures. Accordingly, actual results could differ from those estimates. Significant estimates used in preparing the unaudited condensed consolidated financial statements include those assumed in revenue recognition and the valuation of stock-based compensation expense. On an ongoing basis, management reviews these estimates and assumptions. Though the impact of the COVID-19 pandemic to its business and operating results presents additional uncertainty, the Company continues to use the best information available to inform its significant accounting estimates. Investments Short-term investments consist of investments in debt securities, specifically in U.S. Treasury bills. Any short-term investments that have original maturities of three months or less are classified as cash equivalents on the Condensed Consolidated Balance Sheet. All short-term investments are classified as held-to-maturity, as the Company has both the positive intent and the ability to hold these securities to maturity. Held-to-maturity debt securities are recorded at amortized cost, which approximates fair value. As U.S. Treasury bills are risk-free and will be held until they mature, any declines in fair value are considered temporary. Investments in equity securities consist of investments in the common stock of entities traded in active markets. The Company does not have the ability to exercise significant influence over any entities. Therefore, initial investments are recorded at cost, and are remeasured at fair value as of the balance sheet date. Any gains or losses resulting from the change in fair value is recorded in net income. The investments in equity securities are classified as current assets. Fair value measurement Financial assets and liabilities are measured at fair value, which is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs. The following is a fair value hierarchy based on three levels of inputs, of which the first two are considered observable and the last unobservable, that may be used to measure fair value: • Level 1 — Quoted prices in active markets for identical assets or liabilities. • Level 2 — Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities. • Level 3 — Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities. As of September 30, 2022, the Company held short-term investments in U.S. Treasury bills. These short-term investments are recorded at amortized cost, which approximates fair value. Please refer to "Note 3. Investments” for further information. As the short-term investments consist of U.S. Treasury bills from active markets, the fair value is measured using level 1 inputs. As of September 30, 2022, the Company held investments in equity securities. As the investments in equity securities consist of common stock from active markets, the fair value is measured using level 1 inputs. The following table presents the activity for investments in equity securities measured at fair value for the six months ended September 30, 2022: Fair Value Measurements Using Quoted Prices in Active Markets (Level 1) Investment in Equity Securities (in thousands) Balance at March 31, 2022 $ — Purchases at cost 1,061 Sales (368 ) Loss on investment in equity securities (75 ) Balance at September 30, 2022 $ 618 Net Loss Per Share Basic and diluted net loss per share has been computed using the weighted-average number of shares of common stock outstanding during the period. The weighted-average number of shares used to compute diluted loss per share excludes any assumed exercise of stock options, shares reserved for purchase under the Company’s 2016 Employee Stock Purchase Plan (“ESPP”), the assumed vesting of restricted stock units (“RSUs”), and shares subject to repurchase as the effect would be anti-dilutive. No dilutive effect was calculated for the three and six months ended September 30, 2022 and 2021 as the Company reported a net loss for each respective period and the effect would have been anti-dilutive. Common stock equivalents excluded from computing diluted net loss per share due to their anti-dilutive effect were approximately 1.4 million at September 30, 2022 and 0.7 million at September 30, 2021. Revenue recognition The Company generates revenues from the licensing of intellectual property. Licenses The Company has entered into a license agreement with a company that includes the following: (i) non-refundable upfront fees and (ii) royalties based on specified percentages of net product sales, if any. At the initiation of the agreement, the Company has analyzed whether it results in a contract with a customer under Topic 606. The Company has considered a variety of factors in determining the appropriate estimates and assumptions under these arrangements, such as whether the Company is a principal vs. agent, whether the elements are distinct performance obligations, whether there are determinable stand-alone prices, and whether any licenses are functional or symbolic. The Company has evaluated each performance obligation to determine if it can be satisfied and recognized as revenue at a point in time or over time. Typically, non-refundable upfront fees have been considered fixed, while sales-based royalty payments have been identified as variable consideration which must be evaluated to determine if it has been constrained and, therefore, excluded from the transaction price. Please refer to “Note 5: Collaborative Research, Development, and License Agreements” for further information. Recent Accounting Pronouncements From time to time, new accounting pronouncements are issued by the Financial Accounting Standards Board (“FASB”) or other standard setting bodies. Unless otherwise stated, the Company believes that the impact of the recently issued accounting pronouncements that are not yet effective will not have a material impact on its consolidated financial position or results of operations upon adoption. |
Investments
Investments | 6 Months Ended |
Sep. 30, 2022 | |
Investments All Other Investments [Abstract] | |
Investments | Note 3. Investments Short-term investments consist of investments in debt securities, specifically in U.S. Treasury bills. There were no unrealized gains or losses recorded on short-term investments for the three and six months ended September 30, 2022. As of September 30, 2022, the Company held $10.0 million of short-term investments in six month treasury bills. For the three and six months ended September 30, 2022, there was less than $0.1 million of interest income related to the short-term investments. Investments in equity securities consist of investments in the common stock of entities traded in active markets. For the six months ended September 30, 2022, there was $1.1 million of equity securities purchased, and $0.4 million of equity securities sold. As of September 30, 2022, the fair value of investment in equity securities was $0.6 million, resulting in a $0.1 million unrealized loss on investment in equity securities. |
Stockholders' Equity
Stockholders' Equity | 6 Months Ended |
Sep. 30, 2022 | |
Equity [Abstract] | |
Stockholders' Equity | Note 4. Stockholders’ Equity Stock-based Compensation Expense and Valuation Information Stock-based awards include stock options and RSUs under the Company’s Amended and Restated 2012 Equity Incentive Plan (“2012 Plan”), inducement awards, performance-based RSUs under an Incentive Award Performance-Based Restricted Stock Unit Agreement, the Company’s 2021 Inducement Equity Incentive Plan (“Inducement Plan”), and rights to purchase stock under the ESPP. The Company calculates the grant date fair value of all stock-based awards in determining the stock-based compensation expense. Stock-based compensation expense for all stock-based awards consists of the following (in thousands): Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2022 September 30, 2021 September 30, 2022 September 30, 2021 Research and development $ 125 $ 80 $ 246 $ 156 General and administrative $ 548 $ 346 $ 1,087 $ 685 Total $ 673 $ 426 $ 1,333 $ 841 The total unrecognized compensation cost related to unvested stock option grants as of September 30, 2022 was approximately $3.4 million and the weighted average period over which these grants are expected to vest is 2.3 years. The total unrecognized compensation cost related to unvested RSUs (not including performance-based RSUs) as of September 30, 2022 was approximately $0.1 million, which will be recognized over a weighted average period of 2.38 years. The Company uses either the Black-Scholes or Monte Carlo option-pricing models to calculate the fair value of stock options, depending on the complexity of the equity grants. Stock-based compensation expense is recognized over the vesting period using the straight-line method. The assumed dividend yield is based on the Company’s expectation of not paying dividends in the foreseeable future. The Company uses the Company-specific historical volatility rate as the indicator of expected volatility. The risk-free interest rate assumption is based on U.S. Treasury rates. The weighted average expected life of options was estimated using the average of the contractual term and the weighted average vesting term of the options. The measurement and classification of share-based payments to non-employees is consistent with the measurement and classification of share-based payments to employees. The fair value of stock options was estimated at the grant date using the following weighted average assumptions: Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2022 September 30, 2021 September 30, 2022 September 30, 2021 Dividend yield — — — — Volatility 95.93 % 116.83 % 95.41 % 116.83 % Risk-free interest rate 3.30 % 0.73 % 3.18 % 0.73 % Expected life of options 6.00 years 6.00 years 6.00 years 6.00 years Weighted average grant date fair value $ 1.85 $ 6.52 $ 1.99 $ 6.52 The fair value of each RSU and performance-based RSU is recognized as stock-based compensation expense over the vesting term of the award. The fair value is based on the closing stock price on the date of the grant. The Company uses the Black-Scholes valuation model to calculate the fair value of shares issued pursuant to the ESPP. Stock-based compensation expense is recognized over the purchase period using the straight-line method. The fair value of ESPP shares was estimated at the purchase period commencement date using the following assumptions: Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2022 September 30, 2021* September 30, 2022 September 30, 2021* Dividend yield — — — — Volatility 86.58 % 0.00 % 86.58 % 0.00 % Risk-free interest rate 3.34 % 0.00 % 3.34 % 0.00 % Expected term 6 months — 6 months — Grant date fair value $ 0.82 $ — $ 0.82 $ — *There were no participants in the ESPP for the purchase periods beginning March 1, 2021 or September 1, 2021. The assumed dividend yield is based on the Company’s expectation of not paying dividends in the foreseeable future. The Company uses the Company-specific historical volatility rate as the indicator of expected volatility. The risk-free interest rate assumption is based on U.S. Treasury rates. The expected life is the 6-month purchase period. There was one participant in the ESPP for the current purchase period (beginning September 1, 2022). Preferred Stock The Company is authorized to issue 25,000,000 shares of preferred stock. There are no shares of preferred stock currently outstanding, and the Company has no current plans to issue shares of preferred stock. Common Stock The Company previously had an effective shelf registration statement on Form S-3 (File No. 333-222929) and the related prospectus previously declared effective by the SEC on February 22, 2018 (the “2018 Shelf”), which registered $100.0 million of common stock, preferred stock, warrants and units, or any combination of the foregoing, that was set to expire on February 22, 2021. On January 19, 2021, the Company filed a shelf registration statement on Form S-3 (File No. 333-252224) to register $150.0 million of the Company’s common stock, preferred stock, debt securities, warrants and units, or any combination of the foregoing (the “2021 Shelf”) and a related prospectus. The 2021 Shelf was declared effective by the SEC on January 29, 2021 and replaced the 2018 Shelf at that time. On March 16, 2018, the Company entered into a Sales Agreement (“Sales Agreement”) with H.C. Wainwright & Co., LLC and Jones Trading Institutional Services LLC (each an “Agent” and together, the “Agents”). On January 29, 2021, the Company filed a prospectus supplement to the 2021 Shelf (the “ATM Prospectus Supplement”), pursuant to which the Company may offer and sell, from time to time through the Agents, shares of its common stock in ATM sales transactions having an aggregate offering price of up to $50.0 million. Any shares offered and sold will be issued pursuant to the 2021 Shelf. During the three and six months ended September 30, 2022, the Company issued zero shares of common stock in ATM offerings under the ATM Prospectus Supplement. As of September 30, 2022, the Company has sold an aggregate of 1,580,862 shares of common stock in ATM offerings under the ATM Prospectus Supplement, with gross proceeds of approximately $21.7 million. As of September 30, 2022, there was approximately $100.0 million available for future offerings under the 2021 Shelf (excluding amounts available but not yet issued under the ATM Prospectus Supplement), and approximately $28.3 million available for future offerings through the Company’s ATM program under the ATM Prospectus Supplement. In March 2021, the Company’s Board of Directors (“Board”) approved the Inducement Plan. The Inducement Plan authorized the issuance of up to 750,000 shares of common stock for awards of incentive stock options, non-statutory stock options, stock appreciation rights, restricted stock, RSUs, performance units, performance shares, and other stock or cash awards. RSUs The following table summarizes the Company’s RSUs (not including performance-based RSUs) activity from March 31, 2022 through September 30, 2022: Number of Shares Weighted Average Price Unvested at March 31, 2022 15,500 $ 10.58 Granted — $ — Vested (2,726 ) $ 11.07 Cancelled / forfeited — $ — Unvested at September 30, 2022 12,774 $ 10.47 Stock Options During the three and six months ended September 30, 2022 under the 2012 Plan, 126,262 and 199,921 stock options were granted at various exercise prices, respectively. On October 7, 2021, the Company granted 30,000 and 7,500 stock options, respectively, to its Executive Chairman and its Chief Scientific Officer under the 2012 Plan. These stock options have unique vesting criteria based on specific Company performance conditions. The vesting criteria relates to the Company closing a seven-figure cash up front deal with a major pharmaceutical company. As of September 30, 2022, management estimated there was a 0% probability of achievement, and therefore no expense has been recorded to date. The following table summarizes the Company’s stock option activity from March 31, 2022 to September 30, 2022: Options Outstanding Weighted Average Exercise Price Aggregate Intrinsic Value Outstanding at March 31, 2022 1,203,671 $ 7.36 $ 71,650 Options granted 199,921 $ 2.56 $ — Options cancelled / forfeited — $ — $ — Options exercised — $ — $ — Outstanding at September 30, 2022 1,403,592 $ 6.68 $ 1,503 Vested and Exercisable at September 30, 2022 339,232 $ 7.57 $ — The weighted average remaining contractual term of stock options exercisable and outstanding at September 30, 2022 was approximately 8.27 years Employee Stock Purchase Plan In June 2016, purchase common stock through payroll deductions, limited to 15 percent of each employee’s compensation up to $ 25,000 per employee per year or shares per employee per six -month purchase period. Shares under the ESPP are purchased at 85 percent of the fair market value at the lower of (i) the closing price on the first trading day of the six-month purchase period or (ii) the closing price on the last trading day of the six-month purchase period. The initial offering period commenced in September 2016 . At September 3 0 , 202 2 , there were 59,435 shares available for purchase under the ESPP. Common Stock Reserved for Future Issuance Common stock reserved for future issuance consisted of the following at September 30, 2022: Common stock issuable pursuant to options outstanding and reserved under the 2012 Plan 1,353,592 Common stock reserved under the 2012 Plan 510,412 Common stock reserved under the ESPP 59,435 Common stock reserved under the 2021 Inducement Equity Plan 700,000 Common stock issuable pursuant to restricted stock units outstanding under the 2012 Plan 12,774 Common stock issuable pursuant to options outstanding and reserved under the Inducement Plan 50,000 Total at September 30, 2022 2,686,213 |
Collaborative Research, Develop
Collaborative Research, Development, and License Agreements | 6 Months Ended |
Sep. 30, 2022 | |
Organization Consolidation And Presentation Of Financial Statements [Abstract] | |
Collaborative Research, Development, and License Agreements | Note 5. Collaborative Research, Development, and License Agreements License Agreements From June 2021 to February 2022, certain patents owned or sublicensed by the Company became the subject of IPR proceedings filed by Cellink AB and its subsidiaries, MatTek Incorporated and Visikol, Inc. (collectively, “BICO Group AB”). The Company and BICO Group AB were also engaged in litigation regarding patent infringement during the same time period. On February 22, 2022, the Company and BICO Group AB signed a settlement and patent license agreement (“License Agreement”) to close all matters noted above. In addition to closing all legal matters and patent disputes noted above, as part of the agreement, the Company agreed to grant a non-exclusive license to BICO Group AB to use the Company’s aforementioned patents for its business operations of manufacturing and selling bioprinters as well as bioinks. The Company concluded that the nature of the license granted represents functional intellectual property. As part of the License Agreement, BICO Group AB agreed to pay the Company a one-time, nonrefundable upfront fee of $1,500,000. Based on Topic 606, the Company concluded that the performance obligation related to this upfront fee consisted of the Company filing stipulations of dismissal of all legal matters noted above, as well as the Company granting the non-exclusive license of the aforementioned patents within five days of receiving the upfront payment. The conditions of the performance obligation were satisfied, and therefore the Company recognized revenue of $1,500,000 on February 22, 2022, the executed date of the License Agreement. Additionally, as part of the License Agreement, BICO Group AB agreed to pay the Company ongoing sales-based royalties (based on percentages of BICO Group AB’s net sales) for the use of the granted license. The sales-based royalties became effective beginning on February 22, 2022, the effective date of the License Agreement, and continue until the expiration of the last surviving licensed patent. As the sales-based royalties are required to be paid 45 days after the end of every quarter, there is variable consideration that must be estimated to determine royalty revenue within a given reporting period. For the three and six months ended September 30, 2022, the Company recorded $77,000 There is an additional performance obligation for sales-based royalties occurring from July 1, 2022 to September 30, 2022. As the sales-based royalties are required to be paid 45 days after the end of every quarter, there is variable consideration that must be estimated to determine royalty revenue within a given reporting period. However, after analyzing all available information, the Company concluded that there are constraints on the estimates of variable consideration because there is a lack of complete and accurate information available. BICO Group AB has been unable to timely deliver complete sales reports by product as stipulated in the License Agreement. Therefore, the Company concluded that there is a risk of significant reversal when the uncertainty associated with the variable consideration is resolved. As a result, no revenue is recognized related to this performance obligation for the three months ended September 30, 2022. Also as part of the License Agreement, certain patents involved in the agreement are sublicensed by the Company from the University of Missouri and Clemson University. See below for further information. University of Missouri In March 2009, the Company entered into a license agreement with the Curators of the University of Missouri to in-license certain technology and intellectual property relating to self-assembling cell aggregates and to intermediate cellular units. The Company received the exclusive worldwide rights to commercialize products comprising this technology for all fields of use. The Company is required to pay the University of Missouri royalties ranging from 1% to 3% of net sales of covered tissue products, and of the fair market value of covered tissues transferred internally for use in the Company’s commercial service business, depending on the level of net sales achieved by the Company each year. The Company paid minimum annual royalties of $25,000 in January 2022 and January 2021 for their respective calendar years, which is credited against royalties due during the subsequent twelve months. No payments have been made in excess of the minimum annual royalties in the years ended March 31, 2022 and 2021. The license agreement terminates upon expiration of the patents licensed and is subject to certain conditions as defined in the license agreement, which is expected to expire after 2029. The license agreement with the University of Missouri also includes an additional sales royalty of 3% of all revenue received from a sublicensee, when such sublicense is entered pursuant to settlement of litigation. Such revenue shall include, but not be limited to, all option fees, license issue fees (up-front payments), license maintenance fees, equity, and all royalty payments. Such revenue shall not include research funding provided to licensee by sublicensee. However, per the agreement, in the event that the Company defends the technology by litigation, it can offset any royalties due by legal expenses incurred. As of September 30, 2022, the Company’s legal expenses exceeded royalties owed from the upfront payment and sales-based royalties related to the License Agreement. Therefore, no royalty expense to the University of Missouri was recorded for the six months ended September 30, 2022. No royalty expense related to sales-based royalties has been recorded to date. Clemson University In May 2011, the Company entered into a license agreement with Clemson University Research Foundation to in-license certain technology and intellectual property relating to ink-jet printing of viable cells. The Company received the exclusive worldwide rights to commercialize products comprising this technology for all fields of use. The Company is required to pay the university royalties ranging from 1.5% to 3% of net sales of covered tissue products and the fair market value of covered tissues transferred internally for use in the Company’s commercial service business, depending on the level of net sales reached each year. The license agreement terminates upon expiration of the patents licensed, which are expected to expire in May 2024, and is subject to certain conditions as defined in the license agreement. Minimum annual royalty payments of $20,000 were due for each of the two years beginning with calendar 2014, and $40,000 per year beginning with calendar 2016. Royalty payments of $40,000 were made in each of the years ended March 31, 2022 and 2021. The annual minimum royalty is creditable against royalties owed during the same calendar year. In addition to the annual royalties noted above, the University is owed 40% of all payments including but not limited to, upfront payments, license fees, issue fees, maintenance fees, and milestone payments received from third parties, including sublicensees, in consideration for sublicensing rights to licensed products. However, per the agreement, in the event that the Company defends the technology by litigation, it can offset any royalties due by legal expenses incurred. As of September 30, 2022, the Company’s legal expenses exceeded royalties owed from the upfront payment and sales-based royalties related to the License Agreement. Therefore, no royalty expense to Clemson University was recorded for the six months ended September 30, 2022. No royalty expense related to sales-based royalties has been recorded to date. |
Commitments and Contingencies
Commitments and Contingencies | 6 Months Ended |
Sep. 30, 2022 | |
Commitments And Contingencies Disclosure [Abstract] | |
Commitments and Contingencies | Note 6. Commitments and Contingencies Legal Matters In addition to commitments and obligations in the ordinary course of business, the Company may be subject, from time to time, to various claims and pending and potential legal actions arising out of the normal conduct of its business. The Company assesses contingencies to determine the degree of probability and range of possible loss for potential accrual in its financial statements. Because litigation is inherently unpredictable and unfavorable resolutions could occur, assessing litigation contingencies is subjective and requires judgments about future events. When evaluating contingencies, the Company may be unable to provide a meaningful estimate due to a number of factors, including the procedural status of the matter in question, the presence of complex or novel legal theories, and/or the ongoing discovery and development of information important to the matters. In addition, damage amounts claimed in litigation against it may be unsupported, exaggerated or unrelated to possible outcomes, and as such are not meaningful indicators of its potential liability. The Company regularly reviews contingencies to determine the adequacy of its accruals and related disclosures. During the period presented, the Company has not recorded any accrual for loss contingencies associated with any claims or legal proceedings. However, the outcome of legal proceedings and claims brought against the Company is subject to significant uncertainty. Therefore, although management considers the likelihood of such an outcome to be remote, if one or more legal matters were resolved against the Company in a reporting period, the Company’s consolidated financial statements for that reporting period could be materially adversely affected . |
Leases
Leases | 6 Months Ended |
Sep. 30, 2022 | |
Leases [Abstract] | |
Leases | Note 7. Leases After the initial adoption of Accounting Standards Codification Topic 842 (“ASC 842”), on an on-going basis, the Company evaluates all contracts upon inception and determines whether the contract contains a lease by assessing whether there is an identified asset and whether the contract conveys the right to control the use of the identified asset in exchange for consideration over a period of time. If a lease is identified, the Company will apply the guidance from ASC 842 to properly account for the lease. Operating Leases From October 2019 to July 2021, the Company rented office space in Solana Beach, California. This agreement was a month-to-month contract and could be terminated at-will by either party at any time. As such, the Company concluded that this agreement did not contain a lease and was expensed as incurred (referred to as “rent expense”). Monthly rental payments were approximately $4,000 per month. On November 23, 2020, the Company entered into two lease agreements, pursuant to which the Company temporarily leased approximately 3,212 square feet of lab and office space (the “Temporary Lease”) in San Diego and permanently leased approximately 8,051 square feet of lab and office space (the “Permanent Lease”) in San Diego once certain tenant improvements for the Company’s permanent premises were completed by the landlord and the premises were ready for occupancy. Additionally, on November 17, 2021, the Permanent Lease was amended to add an additional 2,892 square feet of office space in the same building. The Temporary Lease commenced on November 27, 2020 and served as temporary premises until the Permanent Lease was ready for occupancy. The Permanent Lease commenced on December 17, 2021 and is intended to serve as the Company’s permanent premises for approximately sixty-two months. Monthly rental payments will be approximately $40,800 with 3% annual escalators. The Company determined that the Temporary Lease is considered a short term lease under ASC 842 and therefore elected an accounting policy for short term leases to recognize lease payments as an expense on a straight-line basis over the lease term (referred to as “short term lease expense”). Variable lease expenses related to the short term lease, such as payments for additional monthly fees to cover the Company’s share of certain facility expenses (common area maintenance, or CAM) are expensed as incurred. The Company determined that the Permanent Lease is considered an operating lease under ASC 842, and therefore upon the lease commencement date of December 17, 2021, recognized lease liabilities and corresponding right-of-use assets of $2.3 million. The Company records operating lease expense on a straight-line basis over the life of the lease (referred to as “operating lease expense”). Variable lease expenses associated with the Company’s leases, such as payments for additional monthly fees to cover the Company’s share of certain facility expenses (common area maintenance, or CAM) are expensed as incurred. The table below summarizes the Company’s lease liabilities and corresponding right-of-use assets as of September 30, 2022 (in thousands): September 30, 2022 ASSETS Operating lease right-of-use assets $ 1,958 Total lease right-of-use assets $ 1,958 LIABILITIES Current Operating lease liability $ 486 Noncurrent Operating lease liability, net of current portion $ 1,515 Total lease liabilities $ 2,001 Weighted average remaining lease term: 4.33 years Weighted average discount rate: 6 % The Company recorded no rent expense for the three and six months ended September 30, 2022, respectively, and approximately $5,000 and $18,000 for the three and six months ended September 30, 2021, respectively. Variable lease expense was approximately $41,000 and $76,000 for the three and six months ended September 30, 2022, respectively, and approximately $9,000 and $18,000 for the three and six months ended September 30, 2021, respectively. For the three and six months ended September 30, 2022, short term lease expense was $0, respectively, and approximately $39,000 and $78,000 for the three and six months ended September 30, 2021, respectively. Lastly, operating lease expense was approximately $129,000 and $258,000 for the three and six months ended September 30, 2022, respectively, and $0 for the three and six months ended September 30, 2021. Cash flows associated with the Company’s operating lease for the three and six months ended September 30, 2022 was approximately $122,000 and $245,000, respectively. Future lease payments relating to the Company’s operating lease liabilities as of September 30, 2022, are as follows (in thousands): Fiscal year ending March 31, 2023 $ 250 Fiscal year ending March 31, 2024 509 Fiscal year ending March 31, 2025 524 Fiscal year ending March 31, 2026 539 Fiscal year ending March 31, 2027 461 Total future lease payments 2,283 Less: Imputed interest (282 ) Total lease obligations 2,001 Less: Current obligations (486 ) Noncurrent lease obligations $ 1,515 |
Concentrations
Concentrations | 6 Months Ended |
Sep. 30, 2022 | |
Risks And Uncertainties [Abstract] | |
Concentrations | Note 8. Concentrations Credit Risk Financial instruments that potentially subject the Company to concentrations of credit risk consist principally of temporary cash and short-term investments. The Company maintains cash and investment balances at various financial institutions located within the United States. Accounts at these institutions are secured by the Federal Deposit Insurance Corporation. Balances may exceed federally insured limits. The Company has not experienced losses in such accounts and management believes that the Company is not exposed to any significant credit risk with respect to its cash and cash equivalents and short-term investments. |
Related Parties
Related Parties | 6 Months Ended |
Sep. 30, 2022 | |
Related Party Transactions [Abstract] | |
Related Parties | Note 9. Related Parties From time to time, the Company will enter into an agreement with a related party in the ordinary course of its business. These agreements are ratified by the Board or a committee thereof pursuant to its related party transaction policy. Viscient Biosciences (“Viscient”) is an entity for which Keith Murphy, the Company’s Executive Chairman, serves as the Chief Executive Officer and President. Dr. Jeffrey Miner, the Company’s Chief Scientific Officer, is also the Chief Scientific Officer of Viscient, and Thomas Jurgensen, the Company’s General Counsel, previously served as outside legal counsel to Viscient through his law firm, Optima Law Group, APC. On December 28, 2020, the Company entered into an intercompany agreement (the “Intercompany Agreement”) with Viscient and Organovo, Inc., the Company’s wholly-owned subsidiary, which included an asset purchase agreement for certain lab equipment. Pursuant to the Intercompany Agreement, agreed to provide Viscient certain services related to 3D bioprinting technology, which includes, but is not limited to, histology services, cell isolation, and proliferation of cells and Viscient agreed to provide certain services related to 3D bioprinting technology, including bioprinter training, bioprinting services, and qPCR assays, in each case on payment terms specified in the Intercompany Agreement and as may be further determined by the parties. In addition, and Viscient each agreed to share certain facilities and equipment and, subject to further agreement, to each make certain employees available for specified projects for the other party at prices to be determined in good faith by the parties. incurred no consulting expenses from Viscient. Additionally, for the three and six months ended September 3 0 , 202 2 , the Company provided approximately $ and $ of histology services to Viscient , respectively . |
Summary of Significant Accoun_2
Summary of Significant Accounting Policies (Policies) | 6 Months Ended |
Sep. 30, 2022 | |
Accounting Policies [Abstract] | |
Basis of Presentation and Principles of Consolidation | Basis of Presentation and Principles of Consolidation The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with U.S. generally accepted accounting principles (“GAAP”) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not necessarily include all information and notes required by GAAP for complete financial statements. The condensed consolidated balance sheet at March 31, 2022 is derived from the Company’s audited consolidated balance sheet at that date. The unaudited condensed consolidated financial statements include the accounts of Organovo and its wholly owned subsidiaries. All material intercompany accounts and transactions have been eliminated in consolidation. In the opinion of management, the unaudited financial information for the interim periods presented reflects all adjustments, which are only normal and recurring, necessary for a fair statement of the Company’s financial position, results of operations, stockholders’ equity and cash flows. These unaudited condensed consolidated financial statements should be read in conjunction with the audited financial statements and notes included in the Company’s Annual Report on Form 10-K for the year ended March 31, 2022, as filed with the Securities and Exchange Commission (“SEC”). Operating results for any interim period are not necessarily indicative of the operating results for any other interim period or the Company’s full fiscal year ending March 31, 2023 (see “ Note 1. Description of Business” |
Liquidity | Liquidity As of September 30, 2022, the Company had cash and cash equivalents of approximately $13.3 million, short-term investments of $10.0 million, restricted cash of approximately $0.1 million and an accumulated deficit of approximately $314.3 million. The restricted cash was pledged as collateral for a letter of credit that the Company is required to maintain as a security deposit under the terms of the lease agreement for its facilities. The Company also had negative cash flows from operations of approximately $4.6 million during the six months ended September 30, 2022. Through September 30, 2022, the Company has financed its operations primarily through the sale of convertible notes, warrants, the private placement of equity securities, the sale of common stock through public and at-the-market (“ATM”) offerings, and through revenue derived from product and research service-based agreements, collaborative agreements, licenses, and grants. During the three and six months ended September 30, 2022, the Company issued zero shares of its common stock through its ATM facility. The Company believes its cash and cash equivalents on hand will be sufficient to meet its financial obligations for at least the next 12 months of operations. As the Company continues to focus its efforts on drug discovery and development, it will need to raise additional capital to implement this business plan. The Company cannot predict with certainty the exact amount or timing for any future capital raises. If required, the Company may seek to raise additional capital through debt or equity financings, or through some other financing arrangement. However, the Company cannot be sure that additional financing will be available if and when needed, or that, if available, it can obtain financing on terms favorable to its stockholders. Any failure to obtain financing when required will have a material adverse effect on the Company’s business, operating results, financial condition and ability to continue as a going concern. |
Use of Estimates | Use of Estimates The preparation of the financial statements in conformity with accounting principles generally accepted in the United States requires management to make estimates and assumptions that affect certain reported amounts and disclosures. Accordingly, actual results could differ from those estimates. Significant estimates used in preparing the unaudited condensed consolidated financial statements include those assumed in revenue recognition and the valuation of stock-based compensation expense. On an ongoing basis, management reviews these estimates and assumptions. Though the impact of the COVID-19 pandemic to its business and operating results presents additional uncertainty, the Company continues to use the best information available to inform its significant accounting estimates. |
Investments | Investments Short-term investments consist of investments in debt securities, specifically in U.S. Treasury bills. Any short-term investments that have original maturities of three months or less are classified as cash equivalents on the Condensed Consolidated Balance Sheet. All short-term investments are classified as held-to-maturity, as the Company has both the positive intent and the ability to hold these securities to maturity. Held-to-maturity debt securities are recorded at amortized cost, which approximates fair value. As U.S. Treasury bills are risk-free and will be held until they mature, any declines in fair value are considered temporary. Investments in equity securities consist of investments in the common stock of entities traded in active markets. The Company does not have the ability to exercise significant influence over any entities. Therefore, initial investments are recorded at cost, and are remeasured at fair value as of the balance sheet date. Any gains or losses resulting from the change in fair value is recorded in net income. The investments in equity securities are classified as current assets. |
Fair value measurement | Fair value measurement Financial assets and liabilities are measured at fair value, which is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs. The following is a fair value hierarchy based on three levels of inputs, of which the first two are considered observable and the last unobservable, that may be used to measure fair value: • Level 1 — Quoted prices in active markets for identical assets or liabilities. • Level 2 — Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities. • Level 3 — Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities. As of September 30, 2022, the Company held short-term investments in U.S. Treasury bills. These short-term investments are recorded at amortized cost, which approximates fair value. Please refer to "Note 3. Investments” for further information. As the short-term investments consist of U.S. Treasury bills from active markets, the fair value is measured using level 1 inputs. As of September 30, 2022, the Company held investments in equity securities. As the investments in equity securities consist of common stock from active markets, the fair value is measured using level 1 inputs. The following table presents the activity for investments in equity securities measured at fair value for the six months ended September 30, 2022: Fair Value Measurements Using Quoted Prices in Active Markets (Level 1) Investment in Equity Securities (in thousands) Balance at March 31, 2022 $ — Purchases at cost 1,061 Sales (368 ) Loss on investment in equity securities (75 ) Balance at September 30, 2022 $ 618 |
Net Loss Per Share | Net Loss Per Share Basic and diluted net loss per share has been computed using the weighted-average number of shares of common stock outstanding during the period. The weighted-average number of shares used to compute diluted loss per share excludes any assumed exercise of stock options, shares reserved for purchase under the Company’s 2016 Employee Stock Purchase Plan (“ESPP”), the assumed vesting of restricted stock units (“RSUs”), and shares subject to repurchase as the effect would be anti-dilutive. No dilutive effect was calculated for the three and six months ended September 30, 2022 and 2021 as the Company reported a net loss for each respective period and the effect would have been anti-dilutive. Common stock equivalents excluded from computing diluted net loss per share due to their anti-dilutive effect were approximately 1.4 million at September 30, 2022 and 0.7 million at September 30, 2021. |
Revenue recognition | Revenue recognition The Company generates revenues from the licensing of intellectual property. Licenses The Company has entered into a license agreement with a company that includes the following: (i) non-refundable upfront fees and (ii) royalties based on specified percentages of net product sales, if any. At the initiation of the agreement, the Company has analyzed whether it results in a contract with a customer under Topic 606. The Company has considered a variety of factors in determining the appropriate estimates and assumptions under these arrangements, such as whether the Company is a principal vs. agent, whether the elements are distinct performance obligations, whether there are determinable stand-alone prices, and whether any licenses are functional or symbolic. The Company has evaluated each performance obligation to determine if it can be satisfied and recognized as revenue at a point in time or over time. Typically, non-refundable upfront fees have been considered fixed, while sales-based royalty payments have been identified as variable consideration which must be evaluated to determine if it has been constrained and, therefore, excluded from the transaction price. Please refer to “Note 5: Collaborative Research, Development, and License Agreements” for further information. |
Recent Accounting Pronouncements | Recent Accounting Pronouncements From time to time, new accounting pronouncements are issued by the Financial Accounting Standards Board (“FASB”) or other standard setting bodies. Unless otherwise stated, the Company believes that the impact of the recently issued accounting pronouncements that are not yet effective will not have a material impact on its consolidated financial position or results of operations upon adoption. |
Summary of Significant Accoun_3
Summary of Significant Accounting Policies (Tables) | 6 Months Ended |
Sep. 30, 2022 | |
Accounting Policies [Abstract] | |
Schedule of Activity for Investments in Equity Securities Measured at Fair Value | The following table presents the activity for investments in equity securities measured at fair value for the six months ended September 30, 2022: Fair Value Measurements Using Quoted Prices in Active Markets (Level 1) Investment in Equity Securities (in thousands) Balance at March 31, 2022 $ — Purchases at cost 1,061 Sales (368 ) Loss on investment in equity securities (75 ) Balance at September 30, 2022 $ 618 |
Stockholders' Equity (Tables)
Stockholders' Equity (Tables) | 6 Months Ended |
Sep. 30, 2022 | |
Class Of Stock [Line Items] | |
Schedule of Stock-based Compensation Expense | Stock-based compensation expense for all stock-based awards consists of the following (in thousands): Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2022 September 30, 2021 September 30, 2022 September 30, 2021 Research and development $ 125 $ 80 $ 246 $ 156 General and administrative $ 548 $ 346 $ 1,087 $ 685 Total $ 673 $ 426 $ 1,333 $ 841 |
Fair Value of Employee Stock Options | The fair value of stock options was estimated at the grant date using the following weighted average assumptions: Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2022 September 30, 2021 September 30, 2022 September 30, 2021 Dividend yield — — — — Volatility 95.93 % 116.83 % 95.41 % 116.83 % Risk-free interest rate 3.30 % 0.73 % 3.18 % 0.73 % Expected life of options 6.00 years 6.00 years 6.00 years 6.00 years Weighted average grant date fair value $ 1.85 $ 6.52 $ 1.99 $ 6.52 |
Summary of Stock Option Activity | The following table summarizes the Company’s stock option activity from March 31, 2022 to September 30, 2022: Options Outstanding Weighted Average Exercise Price Aggregate Intrinsic Value Outstanding at March 31, 2022 1,203,671 $ 7.36 $ 71,650 Options granted 199,921 $ 2.56 $ — Options cancelled / forfeited — $ — $ — Options exercised — $ — $ — Outstanding at September 30, 2022 1,403,592 $ 6.68 $ 1,503 Vested and Exercisable at September 30, 2022 339,232 $ 7.57 $ — |
Common Stock Reserved for Future Issuance | Common stock reserved for future issuance consisted of the following at September 30, 2022: Common stock issuable pursuant to options outstanding and reserved under the 2012 Plan 1,353,592 Common stock reserved under the 2012 Plan 510,412 Common stock reserved under the ESPP 59,435 Common stock reserved under the 2021 Inducement Equity Plan 700,000 Common stock issuable pursuant to restricted stock units outstanding under the 2012 Plan 12,774 Common stock issuable pursuant to options outstanding and reserved under the Inducement Plan 50,000 Total at September 30, 2022 2,686,213 |
Restricted stock units (RSUs) [Member] | |
Class Of Stock [Line Items] | |
Summary of Company's RSUs Activity and Performance-Based RSUs Activity | The following table summarizes the Company’s RSUs (not including performance-based RSUs) activity from March 31, 2022 through September 30, 2022: Number of Shares Weighted Average Price Unvested at March 31, 2022 15,500 $ 10.58 Granted — $ — Vested (2,726 ) $ 11.07 Cancelled / forfeited — $ — Unvested at September 30, 2022 12,774 $ 10.47 |
ESPP Shares [Member] | |
Class Of Stock [Line Items] | |
Fair Value of Employee Stock Options | The fair value of ESPP shares was estimated at the purchase period commencement date using the following assumptions: Three Months Ended Three Months Ended Six Months Ended Six Months Ended September 30, 2022 September 30, 2021* September 30, 2022 September 30, 2021* Dividend yield — — — — Volatility 86.58 % 0.00 % 86.58 % 0.00 % Risk-free interest rate 3.34 % 0.00 % 3.34 % 0.00 % Expected term 6 months — 6 months — Grant date fair value $ 0.82 $ — $ 0.82 $ — *There were no participants in the ESPP for the purchase periods beginning March 1, 2021 or September 1, 2021. |
Leases (Tables)
Leases (Tables) | 6 Months Ended |
Sep. 30, 2022 | |
Leases [Abstract] | |
Schedule of Lease Liabilities and Corresponding Right-of-use Assets | The table below summarizes the Company’s lease liabilities and corresponding right-of-use assets as of September 30, 2022 (in thousands): September 30, 2022 ASSETS Operating lease right-of-use assets $ 1,958 Total lease right-of-use assets $ 1,958 LIABILITIES Current Operating lease liability $ 486 Noncurrent Operating lease liability, net of current portion $ 1,515 Total lease liabilities $ 2,001 Weighted average remaining lease term: 4.33 years Weighted average discount rate: 6 % |
Schedule of Future Lease Payments | Future lease payments relating to the Company’s operating lease liabilities as of September 30, 2022, are as follows (in thousands): Fiscal year ending March 31, 2023 $ 250 Fiscal year ending March 31, 2024 509 Fiscal year ending March 31, 2025 524 Fiscal year ending March 31, 2026 539 Fiscal year ending March 31, 2027 461 Total future lease payments 2,283 Less: Imputed interest (282 ) Total lease obligations 2,001 Less: Current obligations (486 ) Noncurrent lease obligations $ 1,515 |
Summary of Significant Accoun_4
Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($) | 3 Months Ended | 6 Months Ended | |||
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Mar. 31, 2022 | |
Summary Of Significant Accounting Policies [Line Items] | |||||
Cash and cash equivalents | $ 13,265,000 | $ 33,791,000 | $ 13,265,000 | $ 33,791,000 | $ 28,675,000 |
Short-term investments | 9,955,000 | 9,955,000 | 0 | ||
Restricted cash | 143,000 | 111,000 | 143,000 | 111,000 | 143,000 |
Accumulated deficit | $ (314,275,000) | (314,275,000) | $ (307,739,000) | ||
Cash flow from operations | $ 4,631,000 | 3,556,000 | |||
Issuance of common stock | 8,713,268 | 8,713,268 | 8,710,627 | ||
Dilutive effect | $ 0 | $ 0 | $ 0 | $ 0 | |
Common stock equivalents excluded from computing diluted net loss per share | 1,400,000 | 700,000 | |||
At-The-Market Facility [Member] | |||||
Summary Of Significant Accounting Policies [Line Items] | |||||
Issuance of common stock | 0 | 0 |
Summary of Significant Accoun_5
Summary of Significant Accounting Policies - Schedule of Activity for Investments in Equity Securities Measured at Fair Value (Detail) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | |
Schedule of Investments in Equity Securities Measured at Fair Value [Line Items) | ||||
Purchases at cost | $ 1,061 | $ 0 | ||
Sales | (368) | 0 | ||
Loss on investment in equity securities | $ (70) | $ 0 | (75) | $ 0 |
Level 1 [Member] | ||||
Schedule of Investments in Equity Securities Measured at Fair Value [Line Items) | ||||
Balance at March 31, 2022 | 0 | |||
Purchases at cost | 1,061 | |||
Sales | (368) | |||
Loss on investment in equity securities | (75) | |||
Balance at September 30, 2022 | $ 618 | $ 618 |
Investments - Additional Inform
Investments - Additional Information (Detail) - USD ($) | 3 Months Ended | 6 Months Ended | ||
Sep. 30, 2022 | Sep. 30, 2022 | Sep. 30, 2021 | Mar. 31, 2022 | |
Investments [Line Items] | ||||
Unrealized gains or losses on short-term investments | $ 0 | $ 0 | ||
Short-term investments | 9,955,000 | 9,955,000 | $ 0 | |
Purchase of equity securities | 1,061,000 | $ 0 | ||
Sale of equity securities | 368,000 | $ 0 | ||
Fair value of investment in equity securities | 600,000 | 600,000 | ||
Unrealized loss on investment in equity securities | 100,000 | |||
Maximum [Member] | ||||
Investments [Line Items] | ||||
Interest income on short-term investments | 100,000 | 100,000 | ||
Three Month Treasury Bills [Member] | ||||
Investments [Line Items] | ||||
Short-term investments | $ 10,000,000 | $ 10,000,000 |
Stockholders' Equity - Schedule
Stockholders' Equity - Schedule of Stock-based Compensation Expense (Detail) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | ||
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | |
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] | ||||
Total stock-based compensation expense | $ 673 | $ 426 | $ 1,333 | $ 841 |
Research and development | ||||
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] | ||||
Total stock-based compensation expense | 125 | 80 | 246 | 156 |
General and administrative | ||||
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] | ||||
Total stock-based compensation expense | $ 548 | $ 346 | $ 1,087 | $ 685 |
Stockholders' Equity - Stock-ba
Stockholders' Equity - Stock-based Compensation Expense and Valuation Information - Additional Information (Detail) $ in Millions | 3 Months Ended | 6 Months Ended | ||
Sep. 30, 2022 USD ($) Participant | Sep. 30, 2021 | Sep. 30, 2022 USD ($) Participant | Sep. 30, 2021 | |
Class Of Stock [Line Items] | ||||
Total unrecognized compensation cost related to unvested stock option grants | $ 3.4 | $ 3.4 | ||
Expected term | 6 years | 6 years | 6 years | 6 years |
2016 Employee Stock Purchase Plan [Member] | ||||
Class Of Stock [Line Items] | ||||
Expected term | 6 months | |||
Participants enrolled into the employee stock purchase plan | Participant | 1 | 1 | ||
Stock options [Member] | ||||
Class Of Stock [Line Items] | ||||
Total unrecognized compensation cost related, weighted average period | 2 years 3 months 18 days | |||
Restricted stock units (RSUs) [Member] | ||||
Class Of Stock [Line Items] | ||||
Total unrecognized compensation cost related, weighted average period | 2 years 4 months 17 days | |||
Unrecognized stock-based compensation expense | $ 0.1 | $ 0.1 |
Stockholders' Equity - Fair Val
Stockholders' Equity - Fair Value of Employee Stock Options (Detail) - $ / shares | 3 Months Ended | 6 Months Ended | ||
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | |
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] | ||||
Dividend yield | 0% | 0% | 0% | 0% |
Volatility | 95.93% | 116.83% | 95.41% | 116.83% |
Risk-free interest rate | 3.30% | 0.73% | 3.18% | 0.73% |
Expected life of options | 6 years | 6 years | 6 years | 6 years |
Weighted average grant date fair value | $ 1.85 | $ 6.52 | $ 1.99 | $ 6.52 |
Stockholders' Equity - Fair V_2
Stockholders' Equity - Fair Value of ESPP Shares (Detail) - $ / shares | 3 Months Ended | 6 Months Ended | |||
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | ||
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |||||
Dividend yield | 0% | 0% | 0% | 0% | |
Volatility | 95.93% | 116.83% | 95.41% | 116.83% | |
Risk-free interest rate | 3.30% | 0.73% | 3.18% | 0.73% | |
Expected life of options | 6 years | 6 years | 6 years | 6 years | |
Weighted average grant date fair value | $ 1.85 | $ 6.52 | $ 1.99 | $ 6.52 | |
ESPP Shares [Member] | |||||
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |||||
Dividend yield | 0% | 0% | [1] | 0% | 0% |
Volatility | 86.58% | 0% | [1] | 86.58% | 0% |
Risk-free interest rate | 3.34% | 0% | [1] | 3.34% | 0% |
Expected life of options | 6 months | 6 months | |||
Weighted average grant date fair value | $ 0.82 | $ 0 | [1] | $ 0.82 | $ 0 |
[1]There were no participants in the ESPP for the purchase periods beginning March 1, 2021 or September 1, 2021. |
Stockholders' Equity - Preferre
Stockholders' Equity - Preferred Stock - Additional Information (Detail) | Sep. 30, 2022 shares |
Equity [Abstract] | |
Preferred stock, shares authorized | 25,000,000 |
Preferred stock, shares outstanding | 0 |
Stockholders' Equity - Common S
Stockholders' Equity - Common Stock - Additional Information (Detail) - USD ($) | 6 Months Ended | ||
Sep. 30, 2022 | Jan. 29, 2021 | Jan. 19, 2021 | |
Class Of Stock [Line Items] | |||
Securities authorized for offer and sale, amount | $ 150,000,000 | ||
2021 Inducement Equity Plan [Member] | |||
Class Of Stock [Line Items] | |||
Common shares authorized to be issued | 750,000 | ||
2018 Sales Agreement [Member] | |||
Class Of Stock [Line Items] | |||
Equity sales agreement expiration date | Feb. 22, 2021 | ||
ATM Prospectus Supplement [Member] | |||
Class Of Stock [Line Items] | |||
Issuance of common stock from stock options exercises, net, Shares | 1,580,862 | ||
Value of shares sold under equity distribution agreement | $ 21,700,000 | ||
2021 Shelf [Member] | |||
Class Of Stock [Line Items] | |||
Common stock value reserved for future issuance | 100,000,000 | ||
IPO [Member] | |||
Class Of Stock [Line Items] | |||
Securities authorized for offer and sale, amount | 100,000,000 | ||
At-The-Market Facility [Member] | ATM Prospectus Supplement [Member] | |||
Class Of Stock [Line Items] | |||
Common stock value reserved for future issuance | $ 28,300,000 | ||
Issuance of common stock from stock options exercises, net, Shares | 0 | ||
At-The-Market Facility [Member] | ATM Prospectus Supplement [Member] | Maximum [Member] | |||
Class Of Stock [Line Items] | |||
Common stock value reserved for future issuance | $ 50,000,000 |
Stockholders' Equity - Summary
Stockholders' Equity - Summary of Company's RSUs Activity and Performance-Based RSUs Activity (Detail) - Restricted stock units (RSUs) [Member] | 6 Months Ended |
Sep. 30, 2022 $ / shares shares | |
Class Of Stock [Line Items] | |
Beginning balance, Unvested, Number of Shares | shares | 15,500 |
Granted, Number of Shares | shares | 0 |
Vested, Number of Shares | shares | (2,726) |
Canceled / forfeited, Number of Shares | shares | 0 |
Ending balance, Unvested, Number of Shares | shares | 12,774 |
Beginning balance, Unvested, Weighted Average Price | $ / shares | $ 10.58 |
Granted, Weighted Average Price | $ / shares | 0 |
Vested, Weighted Average Price | $ / shares | 11.07 |
Canceled / forfeited, Weighted Average Price | $ / shares | 0 |
Ending balance, Unvested, Weighted Average Price | $ / shares | $ 10.47 |
Stockholders' Equity - Stock Op
Stockholders' Equity - Stock Options and Employee Stock Purchase Plan - Additional Information (Detail) - USD ($) | 3 Months Ended | 6 Months Ended | |||
Oct. 07, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | |
Class Of Stock [Line Items] | |||||
Vesting criteria probability of achievement percentage | 0% | ||||
Expense recorded | $ 0 | ||||
Weighted-average remaining contractual term of stock options exercisable | 8 years 3 months 7 days | ||||
Weighted-average remaining contractual term of stock options outstanding | 8 years 3 months 7 days | ||||
Number of common stock shares approved under ESPP | 2,686,213 | 2,686,213 | |||
Expected term | 6 years | 6 years | 6 years | 6 years | |
2012 Plan [Member] | |||||
Class Of Stock [Line Items] | |||||
Stock options granted | 126,262 | 199,921 | |||
2012 Plan [Member] | Executive Chairman [Member] | |||||
Class Of Stock [Line Items] | |||||
Stock options granted | 30,000 | ||||
2012 Plan [Member] | Chief Scientific Officer [Member] | |||||
Class Of Stock [Line Items] | |||||
Stock options granted | 7,500 | ||||
2016 Employee Stock Purchase Plan [Member] | |||||
Class Of Stock [Line Items] | |||||
Number of common stock shares approved under ESPP | 75,000 | 75,000 | |||
Employee subscription rate | 15% | 15% | |||
Compensation amount per employee | $ 25,000 | ||||
Number of shares per employee | 500 | ||||
Fair market value at discount | 85% | ||||
Purchase period | 6 months | ||||
Initial offering period | 2016-09 | ||||
Description of plan | Shares under the ESPP are purchased at 85 percent of the fair market value at the lower of (i) the closing price on the first trading day of the six-month purchase period or (ii) the closing price on the last trading day of the six-month purchase period. | ||||
Expected term | 6 months | ||||
Shares available for purchase under ESPP | 59,435 | 59,435 |
Stockholders' Equity - Summar_2
Stockholders' Equity - Summary of Stock Option Activity (Detail) | 6 Months Ended |
Sep. 30, 2022 USD ($) $ / shares shares | |
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] | |
Options Outstanding, Beginning balance | shares | 1,203,671 |
Granted, Options Outstanding | shares | 199,921 |
Cancelled / forfeited, Options Outstanding | shares | 0 |
Exercised, Options Outstanding | shares | 0 |
Options Outstanding, Ending balance | shares | 1,403,592 |
Vested and Exercisable, Options Outstanding | shares | 339,232 |
Weighted-Average Exercise Price, Options Beginning balance | $ / shares | $ 7.36 |
Options granted, Weighted-Average Exercise Price | $ / shares | 2.56 |
Options cancelled / forfeited, Weighted-Average Exercise Price | $ / shares | 0 |
Options exercised, Weighted-Average Exercise Price | $ / shares | 0 |
Weighted-Average Exercise Price, Options Ending balance | $ / shares | 6.68 |
Vested and Exercisable, Weighted-Average Exercise Price | $ / shares | $ 7.57 |
Aggregate Intrinsic Value, Options Beginning balance | $ | $ 71,650 |
Options Exercised, Aggregate Intrinsic Value | $ | 0 |
Aggregate Intrinsic Value, Options Ending balance | $ | 1,503 |
Vested and Exercisable, Aggregate Intrinsic Value | $ | $ 0 |
Stockholders' Equity - Common_2
Stockholders' Equity - Common Stock Reserved for Future Issuance (Detail) | Sep. 30, 2022 shares |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |
Common stock reserved for future issuance | 2,686,213 |
Equity Incentive Plan 2012 [Member] | |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |
Common stock reserved for future issuance | 510,412 |
2016 Employee Stock Purchase Plan [Member] | |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |
Common stock reserved for future issuance | 75,000 |
Stock options [Member] | Equity Incentive Plan 2012 [Member] | |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |
Common stock reserved for future issuance | 1,353,592 |
Stock options [Member] | 2016 Employee Stock Purchase Plan [Member] | |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |
Common stock reserved for future issuance | 59,435 |
Stock options [Member] | 2021 Inducement Equity Plan [Member] | |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |
Common stock reserved for future issuance | 700,000 |
Stock options [Member] | Incentive Award Plan [Member] | |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |
Common stock reserved for future issuance | 50,000 |
Restricted stock units (RSUs) [Member] | Equity Incentive Plan 2012 [Member] | |
Share Based Compensation Arrangement By Share Based Payment Award [Line Items] | |
Common stock reserved for future issuance | 12,774 |
Collaborative Research, Devel_2
Collaborative Research, Development, and License Agreements - Additional Information (Detail) - USD ($) | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended | 137 Months Ended | 163 Months Ended | ||||||||||||
Feb. 22, 2022 | Mar. 31, 2022 | Jan. 31, 2022 | Mar. 31, 2021 | Jan. 31, 2021 | May 31, 2011 | Mar. 31, 2009 | Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Mar. 31, 2022 | Mar. 31, 2021 | Sep. 30, 2022 | Sep. 30, 2022 | Mar. 31, 2016 | Mar. 31, 2015 | Mar. 31, 2014 | |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||
Total Revenues | $ 77,000 | $ 0 | $ 77,000 | $ 0 | ||||||||||||||
BICO Group AB [Member] | ||||||||||||||||||
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||
Nonrefundable upfront fee paid | $ 1,500,000 | |||||||||||||||||
Total Revenues | $ 1,500,000 | $ 77,000 | 77,000 | |||||||||||||||
University of Missouri [Member] | ||||||||||||||||||
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||
Royalty fees percentage minimum | 1% | |||||||||||||||||
Royalty fees percentage maximum | 3% | |||||||||||||||||
Minimum annual royalty paid | $ 25,000 | $ 25,000 | ||||||||||||||||
Excess of minimum annual royalties payment | $ 0 | $ 0 | ||||||||||||||||
Expected expiration year of license agreement | 2029 | |||||||||||||||||
Upfront payment | $ 0 | $ 0 | ||||||||||||||||
University of Missouri [Member] | Sublicense Agreements [Member] | ||||||||||||||||||
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||
Percentage of royalty revenue from sublicensee | 3% | |||||||||||||||||
Clemson University [Member] | ||||||||||||||||||
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||
Minimum annual royalty paid | $ 40,000 | $ 40,000 | ||||||||||||||||
Upfront payment | $ 0 | $ 0 | ||||||||||||||||
Minimum annual royalty payment due | $ 40,000 | $ 20,000 | $ 20,000 | |||||||||||||||
Clemson University [Member] | Sublicense Agreements [Member] | ||||||||||||||||||
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||
Percentage of royalty revenue from sublicensee | 40% | |||||||||||||||||
Clemson University [Member] | Licensing Agreements [Member] | ||||||||||||||||||
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] | ||||||||||||||||||
Royalty fees percentage minimum | 1.50% | |||||||||||||||||
Royalty fees percentage maximum | 3% | |||||||||||||||||
Expected expiration year of license agreement | 2024-05 |
Leases - Additional Information
Leases - Additional Information (Details) | 3 Months Ended | 6 Months Ended | 22 Months Ended | |||||
Nov. 17, 2021 ft² | Nov. 23, 2020 USD ($) ft² Agreement | Sep. 30, 2022 USD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2021 USD ($) | Jul. 31, 2021 USD ($) | Dec. 17, 2021 USD ($) | |
Operating Lease [Line Items] | ||||||||
Monthly rental payments | $ 4,000 | |||||||
Number of lease agreement | Agreement | 2 | |||||||
Operating lease, liability | $ 2,001,000 | $ 2,001,000 | $ 2,300,000 | |||||
Rent expense | 0 | $ 5,000 | 0 | $ 18,000 | ||||
Variable lease expense | 41,000 | 9,000 | 76,000 | 18,000 | ||||
Short term lease cost | 0 | 39,000 | 0 | 78,000 | ||||
Operating Lease, Expense | 129,000,000 | $ 0 | 258,000,000 | $ 0 | ||||
Operating cash flows from operating leases | $ 122,000 | $ 245,000 | ||||||
San Diego Temporary Lease [Member] | ||||||||
Operating Lease [Line Items] | ||||||||
Lab and Office space under lease agreement | ft² | 3,212 | |||||||
San Diego Permanent Lease [Member] | ||||||||
Operating Lease [Line Items] | ||||||||
Lab and Office space under lease agreement | ft² | 2,892 | 8,051 | ||||||
Lease term | 62 months | |||||||
Monthly rental payments | $ 40,800 | |||||||
Base rent escalators | 3% |
Leases - Schedule of Lease Liab
Leases - Schedule of Lease Liabilities and Corresponding Right-of-use Assets (Details) - USD ($) $ in Thousands | Sep. 30, 2022 | Mar. 31, 2022 | Dec. 17, 2021 |
Assets | |||
Operating lease right-of-use assets | $ 1,958 | ||
Total lease right-of-use assets | 1,958 | $ 2,153 | |
Current Liabilities | |||
Operating lease liability, current portion | 486 | 479 | |
Noncurrent | |||
Operating lease liability, net of current portion | 1,515 | $ 1,704 | |
Total lease liabilities | $ 2,001 | $ 2,300 | |
Weighted average remaining lease term: | 4 years 3 months 29 days | ||
Weighted average discount rate: | 6% |
Leases - Schedule of Future Lea
Leases - Schedule of Future Lease Payments (Details) - USD ($) $ in Thousands | Sep. 30, 2022 | Mar. 31, 2022 | Dec. 17, 2021 |
Leases [Abstract] | |||
Fiscal year ending March 31, 2023 | $ 250 | ||
Fiscal year ending March 31, 2024 | 509 | ||
Fiscal year ending March 31, 2025 | 524 | ||
Fiscal year ending March 31, 2026 | 539 | ||
Fiscal year ending March 31, 2027 | 461 | ||
Total future lease payments | 2,283 | ||
Less: Imputed interest | (282) | ||
Total lease liabilities | 2,001 | $ 2,300 | |
Less: Current obligations | (486) | $ (479) | |
Operating lease liability, net of current portion | $ 1,515 | $ 1,704 |
Related Parties - Additional In
Related Parties - Additional Information (Detail) - Viscient [Member] - USD ($) | 3 Months Ended | 6 Months Ended |
Sep. 30, 2022 | Sep. 30, 2022 | |
Related Party Transaction [Line Items] | ||
Consulting expenses | $ 0 | $ 0 |
Histology services to related parties | $ 16,000 | $ 27,000 |