Quanterix (QTRX) 10-Q 7 Nov 18 2018 Q3 Quarterly report Financial data

Document and Entity Information

Document and Entity Information - shares	9 Months Ended
	Sep. 30, 2018	Nov. 01, 2018
Document and Entity Information
Entity Registrant Name	Quanterix Corp
Entity Central Index Key	1,503,274
Document Type	10-Q
Document Period End Date	Sep. 30, 2018
Amendment Flag	false
Current Fiscal Year End Date	--12-31
Entity Current Reporting Status	Yes
Entity Filer Category	Non-accelerated Filer
Entity Common Stock, Shares Outstanding		22,197,779
Document Fiscal Year Focus	2,018
Document Fiscal Period Focus	Q3

Condensed Consolidated Balance

Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 51,423	$ 79,682
Accounts receivable (including $18 and $123 from related parties as of September 30, 2018 and December 31, 2017, respectively)	4,648	5,599
Inventory	5,375	3,571
Prepaid expenses and other current assets	1,255	400
Total current assets	62,701	89,252
Restricted Cash	1,000
Property and equipment, net	2,836	1,874
Intangible assets, net	2,512
Goodwill	1,308
Other non-current assets	836	653
Total assets	71,193	91,779
Current liabilities:
Accounts payable (including $19 and $0 to related parties as of September 30, 2018 and December 31, 2017)	3,866	3,552
Accrued compensation and benefits	3,404	2,624
Other accrued expenses (including $199 and $170 to related parties as of September 30, 2018 and December 31, 2017, respectively)	3,217	3,560
Deferred revenue (including $53 and $1,182 with related parties as of September 30, 2018 and December 31, 2017, respectively)	4,755	4,942
Current portion of long term debt		5,036
Total current liabilities	15,242	19,714
Deferred revenue, net of current portion (including $0 and $1,074 with related parties as of September 30, 2018 and December 31, 2017, respectively)	598	1,709
Long term debt, net of current portion	7,586	4,346
Other non-current liabilities	79	144
Total liabilities	23,505	25,913
Commitments and contingencies (Note 11)
Stockholders' equity:
Preferred stock, $0.001 par value: Authorized-5,000,000 shares as of September 30, 2018 and December 31, 2017; no shares issued or outstanding as of September 30, 2018 and December 31, 2017
Common stock, $0.001 par value; Authorized-120,000,000 shares as of September 30, 2018 and December 31, 2017; issued and outstanding-22,151,410 and 21,707,041 shares as of September 30, 2018 and December 31, 2017, respectively	22	22
Additional paid-in capital	214,220	210,196
Accumulated deficit	(166,554)	(144,352)
Total stockholders' equity	47,688	65,866
Total liabilities and stockholders' equity	$ 71,193	$ 91,779

Condensed Consolidated Balanc_2

Condensed Consolidated Balance Sheets (Parenthetical) - USD ($) $ in Thousands	Sep. 30, 2018	Dec. 31, 2017
Condensed Consolidated Balance Sheets
Accounts receivable, related parties	$ 18	$ 123
Accounts payable, related parties	19	0
Other accrued expenses, related parties	199	170
Deferred revenue, current, related parties	53	1,182
Deferred revenue, net of current portion, related parties	$ 0	$ 1,074
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Preferred stock, authorized shares	5,000,000	5,000,000
Preferred stock, shares issued	0	0
Preferred stock, shares outstanding	0	0
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock, authorized shares	120,000,000	120,000,000
Common stock, shares issued	22,151,410	21,707,041
Common stock, shares outstanding	22,151,410	21,707,041

Condensed Consolidated Statemen

Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Total revenue	$ 10,591	$ 5,734	$ 26,755	$ 16,285
Cost of goods sold:
Total costs of goods sold and services	4,996	3,169	14,016	9,179
Gross profit	5,595	2,565	12,739	7,106
Operating expense:
Research and development (including stock compensation expense of $152 and $361 for the three months and nine months ended September 30, 2018, respectively)	4,411	4,224	11,759	12,377
Selling, general and administrative (including stock compensation expense of $1,657 and $2,862 for the three months and nine months ended September 30, 2018, respectively)	8,846	4,728	23,117	13,641
Total operating expenses	13,257	8,952	34,876	26,018
Loss from operations	(7,662)	(6,387)	(22,137)	(18,912)
Interest income (expense), net	30	(240)	21	(735)
Other (expense) income, net	(25)	13	(86)	10
Net loss	(7,657)	(6,614)	(22,202)	(19,637)
Reconciliation of net loss to net loss attributable to common stockholders:
Net loss	(7,657)	(6,614)	(22,202)	(19,637)
Accretion of preferred stock to redemption value		(1,112)		(3,301)
Accrued dividends on preferred stock		(16)		(48)
Net loss attributable to common stockholders	$ (7,657)	$ (7,742)	$ (22,202)	$ (22,986)
Net loss per share attributable to common stockholders, basic and diluted	$ (0.35)	$ (3.13)	$ (1.01)	$ (9.51)
Weighted-average common shares outstanding, basic and diluted	22,070,786	2,475,166	21,917,823	2,416,984
Products
Total revenue	$ 5,962	$ 3,293	$ 15,907	$ 10,055
Cost of goods sold:
Total costs of goods sold and services	3,277	1,905	8,995	5,573
Service and other
Total revenue	3,017	2,172	8,699	5,424
Cost of goods sold:
Total costs of goods sold and services	1,719	1,264	5,021	3,606
Collaboration and license
Total revenue	$ 1,612	$ 269	$ 2,149	$ 806

Condensed Consolidated Statem_2

Condensed Consolidated Statements of Operations and Comprehensive Loss (Parenthetical) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Cost of product revenue, related party activity	$ 36	$ 12	$ 158	$ 164
Stock compensation expense in research and development expenses	152		361
Stock compensation expense in selling, general and administrative expenses	1,657		2,862
Products
Related party revenue	43	10	179	237
Stock compensation expense in cost of goods sold	20		49
Service and other
Related party revenue	34	38	100	129
Stock compensation expense in cost of goods sold	38		121
Collaboration and license
Related party revenue	$ 1,612	$ 269	$ 2,149	$ 806

Condensed Consolidated Statem_3

Condensed Consolidated Statement of Stockholders' Equity - 9 months ended Sep. 30, 2018 - USD ($) $ in Thousands	Common stock	Additional paid-in capital	Accumulated deficit	Total
Beginning Balance at Dec. 31, 2017	$ 22	$ 210,196	$ (144,352)	$ 65,866
Beginning Balance (in shares) at Dec. 31, 2017	21,707,041			21,707,041
Changes in stockholders' equity
Exercise of common stock warrants (in shares)	16,718
Exercise of common stock options and vesting of restricted stock		684		$ 684
Exercise of common stock options and vesting of restricted stock (in shares)	427,651
Common stock issuance offering costs		(53)		(53)
Stock-based compensation expense		3,393		3,393
Net loss			(22,202)	(22,202)
Ending Balance at Sep. 30, 2018	$ 22	$ 214,220	$ (166,554)	$ 47,688
Ending Balance (in shares) at Sep. 30, 2018	22,151,410			22,151,410

Condensed Consolidated Statem_4

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017
Operating activities
Net loss	$ (22,202)	$ (19,637)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization expense	1,020	337
Stock-based compensation expense	3,393	1,431
Non-cash interest expense	133	183
Change in fair value of preferred stock warrants	1	(62)
Changes in operating assets and liabilities:
Accounts receivable	1,160	(287)
Prepaid expenses and other assets	(753)	(358)
Inventory	(976)	(1,035)
Other non-current assets	(33)	(2,039)
Accounts payable	152	697
Accrued compensation and benefits, other accrued expenses and other liabilities	(55)	1,344
Deferred revenue	(2,453)	1,722
Net cash used in operating activities	(20,613)	(17,704)
Investing activities
Purchases of property and equipment	(1,397)	(793)
Purchase of investments	(150)
Acquisitions, net of cash acquired	(3,800)
Net cash used in investing activities	(5,347)	(793)
Financing activities
Proceeds from sale of preferred stock, net of issuance costs		8,423
Proceeds from sale of common stock, net of issuance costs	(53)
Proceeds from exercise of stock warrants		1
Proceeds from stock options exercised	684	72
Proceeds from the issuance of Long Term Debt and warrants, net of issuance costs		(59)
Payments on Long Term Debt	(1,930)	(921)
Net cash (used in) provided by financing activities	(1,299)	7,516
Net decrease in cash and cash equivalents	(27,259)	(10,981)
Cash, restricted cash, and cash equivalents at beginning of period	79,682	29,671
Cash, restricted cash, and cash equivalents at end of period	52,423	18,690
Supplemental cash flow information
Accretion of redeemable convertible preferred stock to redemption value		3,301
Cash paid for interest	$ 506	560
Warrants issued to lenders		119
Purchases of property and equipment included in accounts payable		$ 277

Organization and operations

Organization and operations	9 Months Ended
	Sep. 30, 2018
Organization and operations
Organization and operations	1. Organization and operations Quanterix Corporation (the Company) is a life sciences company that has developed a next generation, ultra‑sensitive digital immunoassay platform that advances precision health for life sciences research and diagnostics. The Company’s platform enables customers to reliably detect protein biomarkers in extremely low concentrations in blood, serum and other fluids that, in many cases, are undetectable using conventional, analog immunoassay technologies. It also allows researchers to define and validate the function of novel protein biomarkers that are only present in very low concentrations and have been discovered using technologies such as mass spectrometry. These capabilities provide the Company’s customers with insight into the role of protein biomarkers in human health that has not been possible with other existing technologies and enable researchers to unlock unique insights into the continuum between health and disease. The Company is currently focusing its platform on protein detection and is also developing its Simoa technology to detect nucleic acids in biological samples. The Company currently markets the Simoa HD‑1 Analyzer, a fully automated immunoassay platform with multiplexing and custom assay capability, and related assay test kits and consumable materials. The Company launched a second immunoassay platform (Quanterix SR-X) in the fourth quarter of 2017 with a more compact footprint than the Simoa HD‑1 Analyzer and less automation designed for lower volume requirements while still allowing multiplexing and custom assay capability. The Company also performs research services on behalf of customers to apply the Simoa technology to specific customer needs. The Company’s primary customers are in the research use only market which includes academic and governmental research institutions, the research and development laboratories of pharmaceutical manufacturers, contract research organizations, and specialty research laboratories. The Company acquired Aushon Biosystems, Inc. (Aushon) in January 2018 and will market and sell Aushon-developed instruments and biomarker assays. In addition, the Company plans to utilize the Aushon CLIA-certified laboratory to enhance its research service offering to customers. Initial Public Offering In December 2017, the Company completed its initial public offering (IPO) in which the Company sold 4,916,480 shares of its common stock at the initial public offering price of $15.00 per share. The Company’s common stock began trading on The Nasdaq Global Market on December 7, 2017. The aggregate net proceeds received from the IPO, net of underwriting discounts and commissions and offering expenses, was $65.6 million. Immediately prior to the completion of the IPO, all then outstanding shares of convertible preferred stock were converted into 14,185,744 shares of common stock. The related carrying value of shares of preferred stock and warrants in the aggregate amount of $143.3 million was reclassified as common stock and additional paid‑in capital. Additionally, the Company filed an amended and restated certificate of incorporation with the Secretary of State of the State of Delaware, effective December 11, 2017 to, among other things, change the authorized number of shares of common stock to 120,000,000 and the authorized number of shares of preferred stock to 5,000,000. Basis of Presentation The interim condensed consolidated financial statements are unaudited. The unaudited condensed consolidated financial statements reflect, in the opinion of our management, all adjustments, consisting of only normal recurring adjustments, necessary for a fair presentation of financial position, results of operations, comprehensive loss and cash flows for each period presented in accordance with United States generally accepted accounting principles (U.S. GAAP) for interim financial information and with the instructions to Form 10‑Q and Article 10 of Regulation S-X. Accordingly, certain information and disclosures normally included in financial statements prepared in accordance with U.S. GAAP have been condensed or omitted. These interim condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and related notes thereto included in our Annual Report on Form 10‑K for the year ended December 31, 2017 filed with the Securities and Exchange Commission on March 19, 2018 (the 2017 Annual Report on Form 10-K). The consolidated financial information as of December 31, 2017 has been derived from the audited 2017 consolidated financial statements included in our 2017 Annual Report on Form 10‑K. Reverse Stock Split On December 4, 2017, the Company effected a reverse stock split of its common stock at a ratio of 1‑for‑3.214. The shares of common stock subject to then outstanding stock options were adjusted accordingly to reflect the reverse stock split. All common stock and related per share amounts presented in these financial statements and related notes have been retroactively adjusted to reflect the 1‑for‑3.214 reverse stock split.

Significant accounting policies

Significant accounting policies	9 Months Ended
	Sep. 30, 2018
Significant accounting policies
Significant accounting policies	2. Significant accounting policies Principles of consolidation The condensed consolidated financial statements have been prepared in accordance with U.S. GAAP and include the accounts of Quanterix Corporation and its wholly‑owned subsidiaries. All material intercompany transactions and balances have been eliminated in consolidation. Use of estimates The preparation of consolidated financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported in the consolidated financial statements and accompanying notes. In making those estimates and assumptions, the Company bases its estimates on historical experience and on various other assumptions believed to be reasonable. The Company’s significant estimates included in the preparation of the consolidated financial statements are related to revenue recognition, fair value of equity instruments and notes receivable, fair value of assets acquired and liabilities assumed in acquisitions, valuation allowances recorded against deferred tax assets, and stock‑based compensation. Actual results could differ from those estimates. Business combinations Under the acquisition method of accounting, the Company allocates the fair value of the total consideration transferred to the tangible and identifiable intangible assets acquired and liabilities assumed based on their estimated fair values on the date of acquisition. The fair values assigned, defined as the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between willing market participants, are based on estimates and assumptions determined by management. The excess consideration over the aggregate fair value of tangible and intangible assets, net of liabilities assumed, is recorded as goodwill. These valuations require significant estimates and assumptions, especially with respect to intangible assets. The Company typically uses the discounted cash flow method to value acquired intangible assets. This method requires significant management judgment to forecast future operating results and establish residual growth rates and discount factors. The estimates used to value and amortize intangible assets are consistent with the plans and estimates that are used to manage the business and are based on available historical information and industry estimates and averages. If the subsequent actual results and updated projections of the underlying business activity change compared with the assumptions and projections used to develop these values, the Company could experience impairment charges. In addition, the Company has estimated the economic lives of certain acquired assets and these lives are used to calculate depreciation and amortization expense. If estimates of the economic lives change, depreciation or amortization expenses could be accelerated or slowed. Restricted Cash Restricted cash represents collateral for a letter of credit issued as security for the lease for the Company’s new headquarters. The restricted cash is long term in nature as the Company will not have access to the funds until more than one year from September 30, 2018. Recent accounting pronouncements The Company is considered to be an “emerging growth company” as defined in the Jumpstart Our Business Startups Act of 2012, as amended (JOBS Act). The JOBS Act provides that an emerging growth company can take advantage of an extended transition period for complying with new or revised accounting standards. Thus, an emerging growth company can delay the adoption of certain accounting standards until those standards would otherwise apply to private companies. The Company has elected to avail itself of this extended transition period and, as a result, the Company will not be required to adopt new or revised accounting standards on the relevant dates on which adoption of such standards is required for other public companies so long as the Company remains an emerging growth company. In May 2014, the FASB issued ASU No. 2014‑09, Revenue from Contracts with Customers (Topic 606) (ASU 2014‑09). The FASB has issued several updates to the standard which (i) clarify the application of the principal versus agent guidance; (ii) clarify the guidance relating to performance obligations and licensing; (iii) clarify assessment of the collectability criterion, presentation of sales taxes, measurement date for non‑cash consideration and completed contracts at transaction; and (iv) clarify narrow aspects of ASC 606 or corrects unintended application of the guidance (collectively, the Revenue ASUs). The Revenue ASUs provide an accounting standard for a single comprehensive model for use in accounting for revenue arising from contracts with customers and supersedes most current revenue recognition guidance. Under Topic 606, an entity recognizes revenue when its customer obtains control of promised goods or services, in an amount that reflects the consideration which the entity expects to receive in exchange for those goods or services. To determine revenue recognition for arrangements that an entity determines are within the scope of Topic 606, the entity performs the following five steps: (i) identify the contract(s) with a customer; (ii) identify the performance obligations in the contract; (iii) determine the transaction price; (iv) allocate the transaction price to the performance obligations in the contract; and (v) recognize revenue when (or as) the entity satisfies a performance obligation. Topic 606 also impacts certain other areas, such as the accounting for costs to obtain or fulfill a contract. The standard also requires disclosure of the nature, amount, timing, and uncertainty of revenue and cash flows arising from contracts with customers. The new revenue standard is effective for the Company for the year ending December 31, 2019 and for all interim periods within such year. The new revenue standard permits two methods of adoption: retrospectively to each prior reporting period presented (the full retrospective method), or retrospectively with the cumulative effect of initially applying the guidance recognized at the date of initial application (the modified retrospective method). The Company currently intends to adopt the new revenue standard on January 1, 2019 using the modified retrospective method. Under this adoption method, the Company will recognize the cumulative effect, if any, of changes in revenue recognition and costs to obtain or fulfill a contract related to prior periods as an adjustment to its opening balance of retained earnings. The Company has formed an implementation team and has completed a preliminary assessment of potential impacts of implementing the new revenue standard. This assessment includes an analysis of the Company’s current portfolio of customer contracts and a review of its historical accounting policies and practices to identify potential differences in applying the new revenue standard. In September 2018, bioMérieux provided to the Company a notice of termination of the BMX Agreement. As a result, all unrecognized deferred revenues associated with the BMX Agreement were immediately recognized in revenues. Therefore, the adoption of ASC 606 on January 1, 2019 will have no impact on the BMX Agreement. The Company continues to hold ongoing negotiations with a diagnostics company and cannot predict at this time whether the unfulfilled performance obligations and the related unamortized deferred revenues under these arrangements will remain open at January 1, 2019. The Company is continuing to evaluate the impact of the new revenue standard on all of its revenues and costs to obtain or fulfill a contract, including those mentioned above, and its assessment may change in the future based on its ongoing evaluation. In February 2016, the FASB issued ASU No. 2016-02, Leases (Topic 842): Recognition and Measurement of Financial Assets and Financial Liabilities (ASU 2016-02). Under ASU 2016-02, lessees will be required to recognize a lease liability and a right-of-use asset for all leases (with the exception of short term leases) at the commencement date. Lessor accounting under ASU 2016-02 is largely unchanged. ASU 2016-02 is effective for the Company for the year ending December 31, 2020. Early adoption is permitted. Under ASU 2016-02, lessees (for capital and operating leases) and lessors (for sales-type, direct financing and operating leases) must apply a modified retrospective transition approach for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. Lessees and lessors may not apply a full retrospective transition approach. The Company is currently evaluating the requirements of ASU 2016-02 and has not yet determined whether adoption of the standard will have a material impact on its consolidated financial statements. In November 2016, the FASB issued ASU No. 2016-18, Statement of Cash Flows (Topic 230): Restricted Cash (ASU 2016-18), requiring restricted cash and cash equivalents to be included in the statement of cash flows. As the Company avails itself of the extended transition period as an emerging growth company under the JOBS Act, the new standard is effective for fiscal years beginning after December 15, 2018 and interim periods within fiscal years beginning after December 15, 2019. Early adoption is permitted in an interim period and any adjustments should be reflected as of the beginning of the fiscal year that includes that interim period. In January 2017, the FASB issued ASU No. 2017-04 Intangibles - Goodwill and Other (Topic 350) - Simplifying the Test for Goodwill Impairment. This ASU eliminates Step 2 from the goodwill impairment test. In addition, income tax effects from any tax deductible goodwill on the carrying amount of the reporting unit should be considered when measuring the goodwill impairment loss, if applicable. The amendments also eliminate the requirements for any reporting unit with a zero or negative carrying amount to perform a qualitative assessment and, if it fails that qualitative test, to perform Step 2 of the goodwill impairment test. An entity still has the option to perform the qualitative assessment for a reporting unit to determine if the quantitative impairment test is necessary. This ASU is effective for annual periods beginning after December 15, 2019 and interim periods within those annual periods. Early adoption is permitted, for interim or annual goodwill impairment tests performed on testing dates after January 1, 2017. The Company does not expect adoption of this ASU to be material to its ongoing financial reporting or on known trends, demands, uncertainties and events in its business. In August 2018, the FASB issued ASU No. 2018-13, “Fair Value Measurement (Topic 820), Disclosure Framework – Changes to the Disclosure Requirements for Fair Value Measurement” . This ASU removed the following disclosure requirements: (1) the amount of and reasons for transfers between Level 1 and Level 2 of the fair value hierarchy; (2) the policy for timing of transfers between levels; and (3) the valuation processes for Level 3 fair value measurements. Additionally, this update added the following disclosure requirements: (1) the changes in unrealized gains and losses for the period included in other comprehensive income for recurring Level 3 fair value measurements held at the end of the reporting period; (2) the range and weighted average of significant unobservable inputs used to develop Level 3 fair value measurements. For certain unobservable inputs, an entity may disclose other quantitative information (such as the median or arithmetic average) in lieu of the weighted average if the entity determines that other quantitative information would be a more reasonable and rational method to reflect the distribution of unobservable inputs used to develop Level 3 fair value measurements. ASU No. 2018-13 will be effective for fiscal years beginning after December 15, 2019 with early adoption permitted. As of September 30, 2018, the Company has not elected to early adopt this guidance but does not expect that the adoption of this guidance will have a material effect on its consolidated financial statements. There have been no other material changes to the significant accounting policies and recent accounting pronouncements previously disclosed in the 2017 Annual Report on Form 10‑K.

Revenue recognition

Revenue recognition	9 Months Ended
	Sep. 30, 2018
Revenue recognition
Revenue recognition	3. Revenue recognition The Company recognizes revenue when (1) persuasive evidence of an arrangement exists, (2) shipment and installation, if applicable, has occurred or services have been rendered, (3) the price to the customer is fixed or determinable and (4) collection of the related receivable is reasonably assured. The Company primarily generates revenue from the sale of products and delivery of services, as well as under license and collaboration agreements. The Company’s product revenue includes the sale of instruments as well as assay kits and consumables which are used to perform tests on the instrument. The Company’s service revenue is generated from services performed in the Company’s Simoa Accelerator Lab under contracts to perform research services on behalf of customers and maintenance and support services. Product revenue Revenue for instrument sales is recognized upon installation at the customer’s location or upon transfer of title to the customer when installation is not required, which is generally the case with sales to distributors. In sales to end‑customers, the Company provides the installation service and often payment is tied to the completion of the installation service. When installation is required, the Company accounts for the instrument and installation service as one unit of accounting and recognizes revenue when installation is completed, assuming all other revenue recognition criteria are met. Instrument transactions often have multiple elements, as discussed below. Included with the purchase of an instrument is a one‑year assurance type product warranty assuring that the instrument is free of material defects and will function according to specifications. In addition, the sale of an instrument includes an implied warranty which is promised to the customer during the pre‑sales process, at the time that the sales quote is issued to the customer. The implied warranty is provided over the same one‑year period as the standard warranty. The services included in the implied warranty are the same as those included in the extended service contracts, and include two bi‑annual preventative maintenance service visits, minor hardware updates and software upgrades, additional training and troubleshooting which is beyond the scope of the standard product warranty. The implied warranty has been identified by the Company as a separate deliverable and unit of accounting. Consideration allocated to the implied one year service type warranty is recognized over the one year period of performance as service and other revenue as described below. Consideration allocated to any other elements is recognized as the goods are delivered or the services are performed. Service and other revenue Service revenue includes revenue from the implied one‑year service type warranty obligation, revenue from extended service contracts, research services performed on behalf of a customer in the Company’s Simoa Accelerator Lab and CLIA lab, and other services that may be performed. Revenue for the implied one‑year service type warranty is initially deferred at the time of instrument revenue recognition and is recognized ratably over a 12‑month period starting on the date of instrument installation. Revenue for extended warranty contracts is recognized ratably over the service period. Revenue for research and development services and other services is generally recognized based on proportional performance of the contract, when the Company’s ability to complete project requirements is reasonably assured. Most of these services are completed in a short period of time from the receipt of the customer’s order. When significant risk exists in the Company’s ability to fulfill project requirements, revenue is recognized upon completion of the contract. Collaboration and license revenue Collaboration and license revenue relates to the Joint Development and License Agreement (JDLA) with bioMérieux SA (bioMérieux) as amended and restated in December 2016 by the Amended and Restated License Agreement (the Amended JDLA) ) and the agreements with a diagnostics company. Refer to Note 11 of the 2017 Annual Report on Form 10-K for a description of these arrangements and the Company’s revenue recognition policies for these agreements. On September 6, 2018, bioMérieux notified the Company that it was terminating the Amended JDLA, forfeiting any future IVD licensing rights to Quanterix’ Simoa technology and enabling Quanterix to consolidate and regain control of all Simoa IVD licensing and IP rights. As a result of the termination the Company recognized $1.6 million in collaboration and license revenue previously held in deferred revenue. Multiple element arrangements Many of the Company’s instrument sales involve the delivery of multiple products and services. The elements of an instrument sale typically include the instrument installation (when required), an implied one year service type warranty, and in some cases the Company may also sell assays, consumables, or other services. Revenue recognition for contracts with multiple deliverables is based on the individual units of accounting determined to exist in the contract. A delivered item is considered a separate unit of accounting when the delivered item has value to the customer on a stand‑alone basis. Items are considered to have stand‑alone value when they are sold separately by any vendor or when the customer could resell the item on a stand‑alone basis. The consideration received is allocated among the separate units of accounting using the relative selling price method, and the applicable revenue recognition criteria are applied to each of the separate units. The Company determines the estimated selling price for deliverables within the arrangement using vendor‑specific objective evidence (VSOE) of selling price, if available. If VSOE is not available, the Company considers if third‑party evidence is available. If third‑party evidence of selling price or VSOE is not available, the Company uses its best estimate of selling price for the deliverable. In order to establish VSOE of selling price, the Company must regularly sell the product or service on a standalone basis with a substantial majority priced within a relatively narrow range. If there are not a sufficient number of standalone sales such that VSOE of selling price cannot be determined, then the Company considers whether third party evidence can be used to establish selling price. Due to the lack of similar products and services sold by other companies within the industry, the Company has not established selling price using third‑party evidence. For product and service sales, the Company determines its best estimate of selling price for instruments, consumables, services and assays using average selling prices over a rolling 12‑month period coupled with an assessment of market conditions, as VSOE and third‑party evidence cannot be established. The Company recognizes revenue for delivered elements only when it determines there are no uncertainties regarding customer acceptance. Distributor transactions In certain markets, the Company sells products and provides services to customers through distributors that specialize in life sciences products. In cases where the product is delivered to a distributor, revenue recognition generally occurs when title transfers to the distributor. The terms of sales transactions through distributors are generally consistent with the terms of direct sales to customers, except the distributors do not require the Company’s services to install the instrument at the end customer and perform the services for the customer that are beyond our standard warranty in the first year following the sale. These transactions are accounted for in accordance with the Company’s revenue recognition policy described herein. Segment Information Operating segments are defined as components of an enterprise about which separate discrete information is available for evaluation by the chief operating decision‑maker in deciding how to allocate resources and assess performance. The Company and the Company’s chief operating decision‑maker reviews the Company’s operations and manages its business as a single operating segment. Net revenue by product and service line are as follows (in thousands): Three months ended September 30, Nine months ended September 30, 2018 2017 2018 2017 Product revenue Instrument and accessories $ 2,269 $ 1,425 $ 6,043 $ 4,881 Consumable and other product 3,693 1,868 9,864 5,174 Total $ 5,962 $ 3,293 $ 15,907 $ 10,055 Service and other revenue Accelerator and CLIA Lab services $ 1,877 $ 1,408 $ 5,576 $ 3,442 Other services 1,140 764 3,123 1,982 Total $ 3,017 $ 2,172 $ 8,699 $ 5,424 The following table reflects total revenue (in thousands) by geography and as a percentage of total revenue, based on the billing address of our customers. North America consists of the United States, Canada and Mexico; EMEA consists of Europe, Middle East, and Africa; and Asia Pacific includes Japan, China, South Korea, Singapore, Malaysia and Australia. Three months ended September 30, Nine months ended September 30, 2018 2017 2018 2017 North America $ 6,515 62 % $ 3,186 56 % $ 16,138 60 % $ 9,629 59 % EMEA 3,526 33 % 1,867 32 % 8,767 33 % 5,093 31 % Asia Pacific 550 5 % 681 12 % 1,850 7 % 1,563 10 % Total $ 10,591 100 % $ 5,734 100 % $ 26,755 100 % $ 16,285 100 %

Net loss per share

Net loss per share	9 Months Ended
	Sep. 30, 2018
Net loss per share
Net loss per share	4. Net loss per share Basic net loss per common share attributable to common stockholders is calculated by dividing the net loss attributable to common stockholders by the weighted‑average number of common shares outstanding during the period, without consideration for potentially dilutive securities. Diluted net loss per share is computed by dividing the net loss attributable to common stockholders by the weighted‑average number of common shares and potentially dilutive securities outstanding for the period determined using the treasury‑stock and if‑converted methods. For purposes of the diluted net loss per share calculation, preferred stock, unvested restricted common stock and stock options are considered to be potentially dilutive securities, but are excluded from the calculation of diluted net loss per share because their effect would be anti‑dilutive and therefore basic and diluted net loss per share were the same for all periods presented. The following table sets forth the outstanding potentially dilutive securities that have been excluded in the calculation of diluted net loss per share because to do so would be anti‑dilutive (in common stock equivalent shares): September 30, 2018 2017 Redeemable convertible preferred stock — 14,176,012 Unvested restricted common stock and restricted stock units 376,949 226,956 Outstanding stock options 2,565,895 2,291,207 Outstanding warrants 76,041 120,657 Total 3,018,885 16,814,832 As of September 30, 2018 and 2017, the Company had an obligation to issue warrants to purchase 93,341 shares of common stock or 300,000 shares of Series A‑3 Preferred Stock, respectively, to a vendor if a contract is terminated prior to a minimum purchase commitment being met. Upon completion of the IPO in December 2017, the warrants to purchase shares of Series A-3 Preferred Stock were converted to warrants to purchase shares of common stock at a 1‑for‑3.214 basis. No amounts are presented in the table above for this obligation to issue a warrant as the issuance of the warrant is not considered probable. The Company’s redeemable convertible preferred stock was entitled to receive dividends based on dividends declared to common stockholders, thereby giving the preferred stockholders the right to participate in undistributed earnings of the Company above the stated dividend rate. However, preferred stockholders did not have a contractual obligation to share in the net losses of the Company. The Company operated in a net loss position for the three and nine months ended September 30, 2017 and, therefore the Company’s accounting for basic and diluted earnings per share was unaffected by the participation rights of the preferred stockholders. The shares of preferred stock outstanding at September 30, 2017 were converted to shares of common stock at the time of the IPO on a 1-for-3.214 basis.

Fair value of financial instrum

Fair value of financial instruments	9 Months Ended
	Sep. 30, 2018
Fair value of financial instruments
Fair value of financial instruments	5. Fair value of financial instruments ASC Topic 820, Fair Value Measurement (Topic 820), establishes a fair value hierarchy for instruments measured at fair value that distinguishes between assumptions based on market data (observable inputs) and the Company’s own assumptions (unobservable inputs). Observable inputs are inputs that market participants would use in pricing the asset or liability based on market data obtained from sources independent of the Company. Unobservable inputs are inputs that reflect the Company’s assumptions about the inputs that market participants would use in pricing the asset or liability, and are developed based on the best information available in the circumstances. Topic 820 identifies fair value as the exchange price, or exit price, representing the amount that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants. As a basis for considering market participant assumptions in fair value measurements, Topic 820 establishes a three‑tier fair value hierarchy that distinguishes between the following: Level 1 inputs are quoted prices (unadjusted) in active markets for identical assets or liabilities. Level 2 inputs are inputs other than quoted prices that are observable for the asset or liability, either directly or indirectly; and Level 3 inputs are unobservable inputs that reflect the Company’s own assumptions about the assumptions market participants would use in pricing the asset or liability. The carrying amount reflected on the balance sheets for cash and cash equivalents, accounts receivable, prepaid expenses and other current assets, accounts payable and accrued liabilities approximated their fair values, due to the short‑term nature of these instruments. The carrying value of the long‑term debt approximates its fair value as the debt arrangement is based on interest rates the Company believes it could obtain for borrowings with similar terms. The Company has an investment in the preferred stock of a privately held company which is recorded within other non‑current assets on a cost basis. This cost method investment’s fair value has not been estimated as there are no identified events or changes in circumstances that would indicate a significant adverse effect on the fair value of the investment and to do so would be impractical. Fair value measurements as of September 30, 2018 are as follows (in thousands): Quoted Significant prices other Significant in active observable unobservable markets inputs inputs Description Total (Level 1) (Level 2) (Level 3) (unaudited) Financial assets Cash equivalents $ 49,310 $ 49,310 $ — $ — Note receivable 150 — — 150 Total $ 49,460 $ 49,310 $ — $ 150 Fair value measurements as of December 31, 2017 are as follows (in thousands): Quoted Significant prices other Significant in active observable unobservable markets inputs inputs Description Total (Level 1) (Level 2) (Level 3) Financial assets Cash equivalents $ 78,182 $ 78,182 $ — $ — Total $ 78,182 $ 78,182 $ — $ — The Company’s asset with fair value categorized as Level 3 consists of a convertible note with a privately held company as more fully described in Note 7, Investments. The fair value of the asset is based on a fair value approach. The most significant assumptions in the valuation assessment are the likelihood of conversion, the financial health of the private company to which the note is issued, and ability of the private company to repay the loan.

Inventory

Inventory	9 Months Ended
	Sep. 30, 2018
Inventory
Inventory	6. Inventory Inventory consists of the following (in thousands): September 30, December 31, 2018 2017 Raw materials $ 1,660 $ 1,032 Work in process 2,363 968 Finished goods 1,352 1,571 Total $ 5,375 $ 3,571 Inventory comprises commercial instruments, assays, and the materials required to manufacture assays.

Investments

Investments	9 Months Ended
	Sep. 30, 2018
Investments
Investments	7. Investments During the third quarter of 2016, the Company purchased a minority interest in preferred stock in a privately held company for $0.3 million. During the third quarter of 2018, the Company was issued a convertible note by a privately held company having a principal amount of $0.2 million. The investments are recorded on a cost basis in other non-current assets on the accompanying balance sheets as the Company does not have a controlling interest, does not have the ability to exercise significant influence over the privately held companies, and the fair value of these equity investments are not readily determinable. The Company performs an impairments analysis at each reporting period to determine if the carrying value must be reduced due to a decrease in the value of the investment, which includes consideration of whether an event or change in circumstances has occurred that may have a significant adverse effect on the fair value of the investment. The Company has determined there was no impairment during the nine months ended September 30, 2018 or in any prior period. The below provides a roll-forward of the fair value of the Company’s convertible note, which include Level 3 inputs (in thousands): For the nine months ended September 30, 2018 Beginning Balance — Additions 150 Ending Balance 150

Other accrued expenses

Other accrued expenses	9 Months Ended
	Sep. 30, 2018
Other accrued expenses
Other accrued expenses	8. Other accrued expenses Other accrued expenses consist of the following (in thousands): September 30, December 31, 2018 2017 Accrued inventory $ 542 $ 835 Accrued royalties 251 221 Accrued professional services 580 346 Accrued development costs 1,533 1,559 Accrued other 311 599 Total accrued expenses $ 3,217 $ 3,560

Redeemable convertible preferre

Redeemable convertible preferred stock	9 Months Ended
	Sep. 30, 2018
Redeemable convertible preferred stock.
Redeemable convertible preferred stock	9. Redeemable convertible preferred stock The Company has a class of authorized preferred stock amounting to 5,000,000 shares as of September 30, 2018 and December 31, 2017. The authorized preferred stock was classified under stockholders’ equity at September 30, 2018 and December 31, 2017. Prior to the IPO in December 2017, the Company had multiple classes of preferred stock outstanding. These shares of preferred stock were converted to shares of common stock at the time of the IPO on 1-for-3.214 shares basis. The reconciliation of net loss attributable to common shareholders in the consolidated statement of operations for the three and nine months ended September 30, 2017 includes an adjustment for accretion of preferred stock to redemption value.

Warrants, stock-based compensat

Warrants, stock-based compensation, stock options, restricted stock and restricted stock units	9 Months Ended
	Sep. 30, 2018
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units	10. Warrants, stock-based compensation, stock options, restricted stock and restricted stock units Warrants During the nine months ended September 30, 2018, the Company issued warrants to purchase common stock to a consultant providing services for the Company. Additionally, during the nine months ended September 30, 2018, warrants were exercised by a holder on a net, non-cash, basis. A summary of warrant activity is as follows: Weighted average Shares exercise price Warrants outstanding as of December 31, 2017 86,090 9.14 Granted 10,000 21.00 Exercised (20,049) 3.35 Warrants outstanding as of September 30, 2018 76,041 12.23 Stock-based compensation Share‑based compensation expense for all stock awards consists of the following (in thousands): Three months ended September 30, Nine months ended September 30, 2018 2017 2018 2017 Cost of product revenue $ 20 $ 7 $ 49 $ 18 Cost of service and other revenue 38 12 121 31 Research and development 152 53 361 126 General and administrative 1,657 551 2,862 1,256 Total $ 1,867 $ 623 $ 3,393 $ 1,431 As of September 30, 2018, under the 2007 Stock Option and Grant Plan (the 2007 Plan), options to purchase 2,015,828 shares of our common stock were outstanding, 805,853 shares of our common stock had been issued and were outstanding pursuant to the exercise of options, 1,128,975 shares of our common stock had been issued and were outstanding pursuant to restricted or unrestricted stock awards, and no shares of our common stock were available for future awards. In connection with the completion of the IPO, the Company terminated the 2007 Plan. In December 2017, the Company adopted the 2017 Employee, Director and Consultant Equity Incentive Plan (the 2017 Plan), under which it may grant incentive stock options, non‑qualified stock options, restricted stock, and other stock‑based awards. As of December 31, 2017, the 2017 Plan allowed for the issuance of up to 1,042,314 shares or options to purchase shares of common stock plus up to 2,490,290 shares of our common stock represented by awards granted under the 2007 Plan that are forfeited, expire or are cancelled without delivery of shares or which result in the forfeiture of shares of common stock back to the Company on or after the date the 2017 Plan became effective. As of September 30, 2018, 110,223 shares were available for grant under the 2017 Plan. In addition, the 2017 Plan contains an “evergreen” provision, which allows for an annual increase in the number of shares of common stock available for issuance under the 2017 Plan on the first day of each fiscal year during the period beginning in fiscal year 2019 and ending in fiscal year 2027. The annual increase in the number of shares shall be equal to the lowest of: 4% of the number of shares of common stock outstanding as of such date; and an amount determined by the Company’s Board of Directors or Compensation Committee. In December 2017, the Company adopted the 2017 Employee Stock Purchase Plan (the 2017 ESPP). As of September 30, 2018, the 2017 ESPP allowed for the issuance of up to 427,305 shares of common stock and 427,305 shares were available for grant under the 2017 ESPP. The 2017 ESPP contains an “evergreen” provision, which allows for an increase on the first day of each fiscal year beginning with fiscal year 2018. The increase in the number of shares shall be equal to the lowest of: 1% of the number of shares of common stock outstanding on the last day of the immediately preceding fiscal year or an amount determined by the Company’s Board of Directors or Compensation Committee. The number of shares available for grant under the 2017 ESPP increased by 218,842 on January 1, 2018 due to this provision. Stock options Under the 2007 Plan and 2017 Plan, stock options may not be granted with exercise prices of less than fair market value on the date of the grant. Options generally vest ratably over a four‑year period with 25% vesting on the first anniversary and the remaining 75% vesting ratably on a monthly basis over the remaining three years. These options expire ten years after the grant date. Activity under the 2007 Plan and the 2017 Plan was as follows: Weighted- Remaining Aggregate average contractual intrinsic exercise life value Options price (in years) (in thousands) Outstanding at December 31, 2017 2,249,843 6.05 7.80 $ 34,695 Granted 629,703 $ 18.57 Exercised (234,015) $ 2.92 Cancelled or forfeited (79,624) $ 12.58 Outstanding at September 30, 2018 2,565,907 $ 9.21 7.85 $ 31,368 Vested and expected to vest at September 30, 2018 2,565,907 $ 9.21 7.85 $ 31,368 Exercisable at September 30, 2018 1,160,407 $ 5.22 6.57 $ 18,795 Using the Black-Scholes option pricing model, the weighted-average fair value of options granted to employees and directors during the nine months ended September 30, 2018 and 2017 was $7.32 and $4.50 per share, respectively. The expense related to awards granted to employees was $0.7 million and $1.8 million for the three and nine months ended September 30, 2018, respectively. The expense related to awards granted to employees was $0.4 million and $0.9 million for the three and nine months ended September 30, 2017, respectively. The intrinsic value of stock options exercised was $0.6 million and $3.4 million for the three and nine months ended September 30, 2018, respectively. The intrinsic value of stock options exercised was less than $0.1 million and $0.2 million for the three and nine months ended September 30, 2017, respectively. Activity related to non-employee awards was not material to the three and nine months ended September 30, 2018 and 2017. At September 30, 2018, there was $7.1 million of total unrecognized compensation cost related to unvested stock options, which is expected to be recognized over the remaining weighted‑average vesting period of 2.81 years. The fair value of stock options granted to employees and directors for their services on the Company’s Board of Directors is estimated on the grant date using the Black‑Scholes option‑pricing model, based on the assumptions noted in the following table: Nine months ended September 30, 2018 2017 Risk - free interest rate 2.82 % 2.0 % Expected dividend yield None None Expected term (in years) 5.85 6.0 Expected volatility 34.98 % 51.7 % Restricted stock Restricted common stock awards represent shares of common stock issued to employees subject to forfeiture if the vesting conditions are not satisfied. In December 2014, the Company issued 78,912 shares of restricted common stock to a director of the Company under the 2007 Plan. Under the terms of the agreement, shares of common stock issued are subject to a four year vesting schedule. Vesting occurs periodically at specified time intervals and specified percentages. In January 2015, the Company issued 781,060 shares of restricted common stock to an executive of the Company under the 2007 Plan. The majority of these shares were issued subject to a four year vesting schedule with 25% vesting on the first anniversary and the remaining vesting 75% ratably on a monthly basis over the remaining three years, while another portion was issued subject to performance based vesting. The vesting of performance based awards is dependent upon achievement of specified financial targets of the Company. The majority of the performance criteria were achieved during the years ended December 31, 2016 and 2015 and the remaining unvested awards with performance conditions are not material. No restricted stock awards were granted during the nine months ended September 30, 2018. A summary of restricted stock activity is as follows: Weighted-average grant date fair value Shares per share Unvested restricted common stock as of December 31, 2017 177,192 $ 3.11 Vested (137,386) $ 3.11 Unvested restricted common stock as of September 30, 2018 39,806 $ 3.12 The expense related to awards granted to employees and directors was $0.1 million and $0.4 million for the three and nine months ended September 30, 2018, respectively. The expense related to awards granted to employees and directors was $0.2 million and $0.5 million for the three and nine months ended September 30, 2017, respectively. At September 30, 2018, there was $0 million of total unrecognized compensation cost related to unvested restricted stock, which is expected to be recognized over the remaining weighted‑average vesting period of 0 years. The aggregate fair value of restricted stock awards that vested during the nine months ended September 30, 2018, based on estimated fair values of the stock underlying the restricted stock awards on the day of vesting, was $1.9 million. Restricted stock units Restricted stock units represent the right to receive shares of common stock upon meeting specified vesting requirements. In the nine months ended September 30, 2018, the Company issued 393,386 restricted stock units to employees of the Company under the 2017 Plan. Under the terms of the agreements, 56,196 of the restricted stock units issued are subject to a four year vesting schedule with 25% vesting on the first anniversary and the remaining vesting 75% ratably on a monthly basis over the remaining three years, 18,200 of the restricted stock units issued are subject to vesting with 50% vesting on December 31, 2018 and 50% vesting on December 31, 2019, 3,100 of the restricted stock units are subject to a four year vesting schedule with 25% vesting on each anniversary, 15,890 of the restricted stock units vest on December 31, 2018, 50,000 of the restricted stock units vested on August 31, 2018, and 250,000 of the restricted stock units vest evenly over 40 months on the last day of each month starting September 30, 2018. A summary of restricted stock unit activity is as follows: Weighted-average grant date fair value Shares per share Unvested restricted stock units as of December 31, 2017 — — Granted 393,386 $ 15.60 Unvested restricted stock units as of September 30, 2018 393,386 $ 15.60 The expense related to awards granted to employees and directors was $1.1 million for the three and $1.2 million for the nine months ended September 30, 2018. At September 30, 2018, there was $5.0 million of total unrecognized compensation cost related to unvested restricted stock, which is expected to be recognized over the remaining weighted‑average vesting period of 3.13 years.

Commitments and contingencies

Commitments and contingencies	9 Months Ended
	Sep. 30, 2018
Commitments and contingencies
Commitments and contingencies	11. Commitments and contingencies License agreements Tufts University In June 2007, the Company entered into a license agreement (the License Agreement) for certain intellectual property with Tufts University (Tufts). Tufts is a related party to the Company due to Tuft’s equity ownership in the Company and because a member of the Company’s Board of Directors was affiliated with Tufts. The License Agreement, which was subsequently amended, is exclusive and sub licensable, and will continue in effect on a country by country basis as long as there is a valid claim of a licensed patent in a country. The Company was committed to pay license and maintenance fees, prior to commercialization, in addition to low single digit royalties on direct sales and services and a royalty on sublicense income. During the three months ended September 30, 2018 and 2017, and the nine months ended September 30, 2018 and 2017, the Company recorded royalty expense of $0.2 million, $0.1 million, $0.5 million and $0.3 million, respectively, in cost of product revenue on the consolidated statements of operations. Other licenses During the year ended December 31, 2012, the Company entered into a license agreement for certain intellectual property with a third party. The non‑exclusive, non‑sublicenseable third party’s license provides the Company access to certain patents specifically for protein detection, and shall be in effect until the expiration of the last licensed patent. In consideration for these rights, the Company committed to certain license fees, milestone payments, minimum annual royalties and a mid‑single digit royalty. The Company is required to make mid‑single digit royalty payments on net sales of products and services which utilize the licensed technology. The Company must pay the greater of calculated royalties on net sales or an annual minimum royalty of $50 thousand. The Company also has certain other licenses related to the purchase of certain antibodies. During the three months ended September 30, 2018 and 2017, and the nine months ended September 30, 2018 and 2017, the Company recorded royalty expense related to these agreements of $0.1 million, less than $0.1 million, $0.3 million and $0.2 million, respectively, in cost of product revenue on the consolidated statements of operations. Lease commitments During the year ended December 31, 2014, the Company entered into a lease agreement for the Company’s current corporate headquarters with a lease term that expires in June 2020. The lease agreement contains a period of free rent and annual increases to rental amounts. The Company executed its right to not extend the current lease. See Note 18 for further discussion of the new lease. In connection with the acquisition of Aushon in January 2018, the Company assumed the existing Aushon lease for facilities in Billerica, Massachusetts. In August 2018 the Company terminated the Aushon lease effective September 1, 2019. The Company is required to pay $75,933 no later than July 1, 2019 in consideration for the early termination. Rent expense is recognized straight‑line over the course of the lease term. As of September 30, 2018, less than $0.1 million of deferred rent expense was recorded in other non‑current liabilities, and less than $0.1 million was recorded in other accrued expenses. The table below includes committed lease expenditures related to the new lease. See Note 18 for discussion of the new lease. As of September 30, 2018, the minimum future rent payments under the lease agreements are as follows (in thousands): Years ending December 31: Remainder of 2018 341 2019 1,861 2020 2,618 2021 3,290 2022 and Forward 32,580 $ 40,690 The Company recorded $0.4 million, $0.2 million, $1.0 million and $0.8 million in rent expense for the three months ended September 30, 2018 and 2017, and the nine months ended September 30, 2018 and 2017, respectively. Development and supply agreement Through the Company’s development agreement with STRATEC Biomedical, as amended in December 2016, the parties agreed on additional development services for an additional fee, which is payable when the additional development is completed. A total of $1.5 million is payable to STRATEC upon completion of the development activities. This amount is being recorded to research and development expense and accrued expenses as the services are performed. The services are expected to be completed during the year ending December 31, 2018. Substantive efforts related to these additional development activities started in the first quarter of 2017. The Company’s supply agreement with STRATEC Biomedical requires the Company to purchase a minimum number of commercial units over a seven‑year period ending in May 2021. If the Company were to fail to purchase a required number of commercial units, the Company would be obligated to pay termination costs plus a fee based on the shortfall of commercial units purchased compared to the required minimum amount. Based on the number of commercial instruments purchased as of September 30, 2018, assuming no additional commercial units were purchased, this fee would equal $11.6 million. The amount the Company could be obligated to pay under the minimum purchase commitment is reduced as each commercial unit is purchased. Also, if the Company terminates the Supply Agreement under certain circumstances and has not purchased a required number of commercial units, it would be obligated to issue warrants to purchase 93,341 shares of common stock (the Supply Warrants) at $0.003214 per share. The Company believes that it will purchase sufficient units to meet the requirements of the minimum purchase commitment and, therefore, has not accrued for any of the potential cash consideration. The Supply Warrants are accounted for at fair value; however, the fair value of the Supply Warrants as of September 30, 2018 and December 31, 2017 was insignificant as there was a low probability of the warrants being issued. Legal contingencies The Company is subject to claims in the ordinary course of business; however, the Company is not currently a party to any pending or threatened litigation, the outcome of which would be expected to have a material adverse effect on its financial condition or the results of its operations. The Company accrues for contingent liabilities to the extent that the liability is probable and estimable.

Long Term Debt

Long Term Debt	9 Months Ended
	Sep. 30, 2018
Long Term Debt
Long Term Debt	12. Long Term Debt Loan agreement On April 14, 2014, the Company executed a Loan Agreement with a lender, as subsequently amended in March 2015, January 2016, March 2017, and August 2018. As of September 30, 2018, there were no additional amounts available to borrow under the debt facility. The interest rate on this term loan is variable based on a calculation of the prime rate less 5.25% with a minimum interest rate of 8%. Interest is paid monthly beginning the month following the borrowing date. At loan inception and in connection with the amendments, the Company issued the lender warrants to purchase shares of stock. The Loan Agreement also contains prepayment penalties and an end of term charge. Fees incurred in execution of the agreements, and the fair value of warrants on the date of grant were accounted for as a reduction in the book value of debt and accreted through interest expense, using the effective interest rate method, over the term of the debt. The end of term charge of $0.5 million, and principal payments of $1.4 million were paid during the nine months ended September 30, 2018. Under the terms of the August 2018 amended agreement, principal payments were delayed until March 2020. The Company accounted for the August 2018 amendment as a modification pursuant to ASC 470-50 and determined that no material change occurred as a result of the modification. The Company voluntarily made principal payments in the months of March, April and May, 2018. No principal payments were made in June, July or August, 2018. Under the amended Loan Agreement, the remaining outstanding principal will be paid upon maturity of the note in March 2020. As of September 30, 2018, the remaining loan balance is classified as a long term liability since all principal payments are due greater than twelve months after the balance sheet date. Debt payment obligations due based on principal payments are as follows (in thousands): Years ending December 31: Remainder of 2018 0 2019 $ 0 2020 7,687 $ 7,687 Non‑cash interest expense related to debt discount amortization and accretion of end of term fees was $0.0 million, $0.1 million, $0.1 million and $0.2 million for the three months ended September 30, 2018 and 2017, and the nine months ended September 30, 2018 and 2017, respectively.

Collaboration and license arran

Collaboration and license arrangements	9 Months Ended
	Sep. 30, 2018
Collaboration and license arrangements
Collaboration and license arrangements	13. Collaboration and license arrangements Joint development and license agreement (JDLA) The Company’s JDLA with bioMérieux, a related party, was amended in 2016. Following the amendment, a total of $3.2 million of consideration was assigned to the deliverables and collaboration activities outlined in the Amended JDLA. The consideration of $3.2 million will be recognized over the performance period which began in the fourth quarter 2016. On September 6, 2018, bioMérieux notified the Company that it was terminating the Amended JDLA, forfeiting any future IVD licensing rights to the Company’s Simoa technology and enabling the Company to consolidate and regain control of all Simoa IVD licensing and IP rights. As a result of the termination, the Company immediately recognized $1.6 million in deferred revenue related to the agreement. The Company recognized revenue of $1.6 million and $2.1 million for the three and nine months ended September 30, 2018, respectively, as collaboration revenue. The Company recognized revenue of $0.3 million and $0.8 million for the three and nine months ended September 30, 2017, respectively, as collaboration revenue. Evaluation and option agreements and license agreement In 2015, the Company entered into three agreements, for three separate fields, with a diagnostic company for the evaluation of the Company’s Simoa technology. These agreements each allowed for the option to negotiate a license agreement. In return, the Company received non‑refundable payments totaling $2.0 million. In December 2016, the diagnostic company exercised one of its options and the parties entered into a license agreement in one of the fields. This agreement has a one‑time non‑refundable license fee of $1.0 million and the right to receive running low single digit royalties on licensed products. The negotiation periods for the other two agreements were extended and the negotiations remain ongoing. Upon execution of the license in one of the fields in December 2016, the $1.0 million license fee, in addition to the $0.8 million allocated to the option for this field, resulted in a total of $1.8 million of consideration being recognized as revenue as there were no remaining undelivered performance obligations. Because the negotiations remain ongoing with respect to the other two fields, the consideration allocated to these options of $1.2 million has been deferred and is recorded as deferred revenue as of September 30, 2018 and December 31, 2017.

Business combinations

Business combinations	9 Months Ended
	Sep. 30, 2018
Business combinations
Business combinations	14. Business combinations On January 30, 2018, the Company completed the acquisition of Aushon pursuant to an Agreement and Plan of Merger dated January 30, 2018 (the “Aushon Acquisition”). The Company acquired Aushon to complement its existing product line, improve its existing research and development capabilities in assay development and software engineering, and expand its customer base. In connection with the closing of the Aushon Acquisition, the Company paid $3.2 million at closing, and an additional $0.8 million in July 2018, the six-month anniversary of the acquisition date. The purchase price allocation is considered preliminary, and additional adjustments may be recorded during the allocation period in accordance with ASC 805. The purchase price allocation will be finalized as the Company receives additional information relevant to the acquisition, including the final valuation and reconciliation of the assets purchased, including tangible and intangible assets, and liabilities assumed. The following table presents the preliminary allocation of the purchase consideration for the transaction as of January 30, 2018 including the contingent consideration and the preliminary allocation of the purchase consideration (in thousands): Fair value of consideration transferred: Cash $ 3,200 Obligation to issue cash 800 Total acquisition consideration $ 4,000 Fair value of assets acquired and liabilities assumed: Cash and cash equivalents $ 199 Accounts receivable 210 Inventory 828 Prepaid expenses 71 Property and equipment and other non-current assets 180 Intangible Assets 2,950 Goodwill 1,308 Total assets acquired 5,746 Contractual obligations (1,155) Accounts payable and accrued liabilities (591) Net assets acquired $ 4,000 The intangible assets identified in the purchase price allocation discussed above include developed technology, trade names and customer relationships. Trade names are amortized over the useful life on a straight-line basis, while developed technology and customer relationships are amortized over their respective useful lives on an accelerated basis reflecting the period of expected derived benefits of the underlying assets. Developed technology consists of products that have reached technological feasibility and trade names represent acquired company and product names. To value the developed technology and trade name assets, the Company utilized a relief from royalty method. Under the methodology, fair value is calculated as the discounted cash flow savings accruing to the owner for not having to pay the royalty. Key assumptions included expected revenue attributable to the assets, royalty rates, discount rate and estimated asset lives. Customer relationships represent the underlying relationships with certain customers to provide ongoing services and continued product sale opportunities. The Company utilized excess earnings methodology to derive the fair value of the customer relationships. Key assumptions included expected attrition of customers rates, operating income margins and discount rate. The Company used a risk-adjusted discount rate of 14.4% in determining the fair value of the intangible assets. The goodwill recorded as a result of the Aushon Acquisition represents the strategic benefits of growing the Company’s product portfolio and the expected revenue growth from increased market penetration from future products and customers. The Company incurred a total of $0.1 million in transaction costs in connection with the transaction, which were included in selling, general and administrative expense within the consolidated statement of operations for the nine months ended September 30, 2018.

Goodwill and Acquired Intangibl

Goodwill and Acquired Intangible Assets	9 Months Ended
	Sep. 30, 2018
Goodwill and Acquired Intangible Assets
Goodwill and Acquired Intangible Assets	15. Goodwill and Acquired Intangible Assets As of September 30, 2018 the carrying amount of goodwill was $1.3 million. The following is a rollforward of our goodwill balance (in thousands): Goodwill Balance as of December 31, 2017 $ — Goodwill acquired 1,308 Balance as of September 30, 2018 $ 1,308 Purchased intangible assets consist of the following (in thousands): Estimated September 30, 2018 Useful Gross Net Life Carrying Accumulated Carrying (in years) Value Amortization Value Developed technology 7 $ 1,650 $ (275) $ 1,375 Customer relationships 10 1,250 (152) 1,098 Trade names 3 50 (11) 39 Total $ 2,950 $ (438) $ 2,512 The Company recorded amortization expense of $0.2 million and $0.4 million, for the three and nine months ended September 30, 2018, respectively. No amortization expense was recognized for the three and nine months ended September 30, 2017. Amortization relating to developed technology is recorded within research and development expense, amortization of customer relationships is recorded within sales and marketing expenses, and amortization of trade names is recorded within general and administrative expenses. Future estimated amortization expense of acquired intangibles as of September 30, 2018 is as follows (in thousands): Remainder of 2018 $ 164 2019 582 2020 500 2021 403 2022 320 Thereafter 543

Related party transactions

Related party transactions	9 Months Ended
	Sep. 30, 2018
Related party transactions
Related party transactions	16. Related party transactions bioMérieux is a customer and also a holder of the Company’s common stock. bioMérieux formerly also had a designee on the Company’s Board of Directors. On September 6, 2018, bioMérieux notified the Company that it was terminating the Amended JDLA. The termination of the agreement resulted in the immediate recognition of the remaining deferred revenue. The Company recognized revenue related to the Amended JDLA with bioMérieux of $1.6 million, $0.3 million, $2.1 million and $0.8 million in the three months ended September 30, 2018 and 2017, and the nine months ended September 30, 2018 and 2017, respectively, from bioMérieux. The Company also had deferred revenue related to this agreement of $0 million and $2.1 million at September 30, 2018 and December 31, 2017, respectively. The Company entered into the License Agreement for certain intellectual property with Tufts. Tufts is a related party to the Company due to Tufts’ equity ownership in the Company and because a member of the Company’s Board of Directors was affiliated with Tufts. During the three months ended September 30, 2018 and 2017 and the nine months ended September 30, 2018 and 2017, the Company recorded royalty expense of $0.2 million, $0.1 million, $0.5 million and $0.3 million, respectively, in cost of product revenue on the consolidated statements of operations and comprehensive loss. During the year ended December 31, 2017, Harvard University became a related party. Revenue recorded from sales to Harvard University were less than $0.1 million for the three and nine months ended September 30, 2018.

Restricted Cash

Restricted Cash	9 Months Ended
	Sep. 30, 2018
Restricted Cash
Restricted Cash	17. Restricted Cash The Company’s restricted cash consists of cash that the Company is contractually obligated to maintain in accordance the terms of the Letter of Credit in the lease agreement. See Note 18 for further discussion.

Subsequent events

Subsequent events	9 Months Ended
	Sep. 30, 2018
Subsequent events
Subsequent events	18. Subsequent events On October 2, 2018, the Company entered into a 137 month (the “Term”) operating lease for the Company’s new headquarters in Billerica, MA. The lease is for approximately 92,000 square feet of office and laboratory space, and will commence on or about April 1, 2019. The monthly rent is approximately $272,000 with approximately a 2.5% increase each year in years 1-5 and 3% increases each year thereafter, plus triple net (“NNN”) costs for operating expenses, taxes, and insurance, and utilities. The lease contains a period of free rent equal to five months plus time the building is under construction. No NNN costs are paid during this five month free rent period. In addition, during the 13 months thereafter, the rent will be reduced to 50% of the stated rent amount, but 100% of the NNN costs will be payable. As part of the lease, the Company was required to enter into a $1.0 million Letter of Credit drawable by the lessor under specifically outlined conditions. The amount of the Letter of Credit will be reduced at 41 and 65 months after the commencement date of the lease to $750,000 and then $250,000, respectively.

Significant accounting polici_2

Significant accounting policies (Policies)	9 Months Ended
	Sep. 30, 2018
Significant accounting policies
Principles of consolidation	Principles of consolidation The condensed consolidated financial statements have been prepared in accordance with U.S. GAAP and include the accounts of Quanterix Corporation and its wholly‑owned subsidiaries. All material intercompany transactions and balances have been eliminated in consolidation.
Use of estimates	Use of estimates The preparation of consolidated financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported in the consolidated financial statements and accompanying notes. In making those estimates and assumptions, the Company bases its estimates on historical experience and on various other assumptions believed to be reasonable. The Company’s significant estimates included in the preparation of the consolidated financial statements are related to revenue recognition, fair value of equity instruments and notes receivable, fair value of assets acquired and liabilities assumed in acquisitions, valuation allowances recorded against deferred tax assets, and stock‑based compensation. Actual results could differ from those estimates.
Business combinations	Business combinations Under the acquisition method of accounting, the Company allocates the fair value of the total consideration transferred to the tangible and identifiable intangible assets acquired and liabilities assumed based on their estimated fair values on the date of acquisition. The fair values assigned, defined as the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between willing market participants, are based on estimates and assumptions determined by management. The excess consideration over the aggregate fair value of tangible and intangible assets, net of liabilities assumed, is recorded as goodwill. These valuations require significant estimates and assumptions, especially with respect to intangible assets. The Company typically uses the discounted cash flow method to value acquired intangible assets. This method requires significant management judgment to forecast future operating results and establish residual growth rates and discount factors. The estimates used to value and amortize intangible assets are consistent with the plans and estimates that are used to manage the business and are based on available historical information and industry estimates and averages. If the subsequent actual results and updated projections of the underlying business activity change compared with the assumptions and projections used to develop these values, the Company could experience impairment charges. In addition, the Company has estimated the economic lives of certain acquired assets and these lives are used to calculate depreciation and amortization expense. If estimates of the economic lives change, depreciation or amortization expenses could be accelerated or slowed.
Restricted Cash	Restricted Cash Restricted cash represents collateral for a letter of credit issued as security for the lease for the Company’s new headquarters. The restricted cash is long term in nature as the Company will not have access to the funds until more than one year from September 30, 2018.
Recent accounting pronouncements	Recent accounting pronouncements The Company is considered to be an “emerging growth company” as defined in the Jumpstart Our Business Startups Act of 2012, as amended (JOBS Act). The JOBS Act provides that an emerging growth company can take advantage of an extended transition period for complying with new or revised accounting standards. Thus, an emerging growth company can delay the adoption of certain accounting standards until those standards would otherwise apply to private companies. The Company has elected to avail itself of this extended transition period and, as a result, the Company will not be required to adopt new or revised accounting standards on the relevant dates on which adoption of such standards is required for other public companies so long as the Company remains an emerging growth company. In May 2014, the FASB issued ASU No. 2014‑09, Revenue from Contracts with Customers (Topic 606) (ASU 2014‑09). The FASB has issued several updates to the standard which (i) clarify the application of the principal versus agent guidance; (ii) clarify the guidance relating to performance obligations and licensing; (iii) clarify assessment of the collectability criterion, presentation of sales taxes, measurement date for non‑cash consideration and completed contracts at transaction; and (iv) clarify narrow aspects of ASC 606 or corrects unintended application of the guidance (collectively, the Revenue ASUs). The Revenue ASUs provide an accounting standard for a single comprehensive model for use in accounting for revenue arising from contracts with customers and supersedes most current revenue recognition guidance. Under Topic 606, an entity recognizes revenue when its customer obtains control of promised goods or services, in an amount that reflects the consideration which the entity expects to receive in exchange for those goods or services. To determine revenue recognition for arrangements that an entity determines are within the scope of Topic 606, the entity performs the following five steps: (i) identify the contract(s) with a customer; (ii) identify the performance obligations in the contract; (iii) determine the transaction price; (iv) allocate the transaction price to the performance obligations in the contract; and (v) recognize revenue when (or as) the entity satisfies a performance obligation. Topic 606 also impacts certain other areas, such as the accounting for costs to obtain or fulfill a contract. The standard also requires disclosure of the nature, amount, timing, and uncertainty of revenue and cash flows arising from contracts with customers. The new revenue standard is effective for the Company for the year ending December 31, 2019 and for all interim periods within such year. The new revenue standard permits two methods of adoption: retrospectively to each prior reporting period presented (the full retrospective method), or retrospectively with the cumulative effect of initially applying the guidance recognized at the date of initial application (the modified retrospective method). The Company currently intends to adopt the new revenue standard on January 1, 2019 using the modified retrospective method. Under this adoption method, the Company will recognize the cumulative effect, if any, of changes in revenue recognition and costs to obtain or fulfill a contract related to prior periods as an adjustment to its opening balance of retained earnings. The Company has formed an implementation team and has completed a preliminary assessment of potential impacts of implementing the new revenue standard. This assessment includes an analysis of the Company’s current portfolio of customer contracts and a review of its historical accounting policies and practices to identify potential differences in applying the new revenue standard. In September 2018, bioMérieux provided to the Company a notice of termination of the BMX Agreement. As a result, all unrecognized deferred revenues associated with the BMX Agreement were immediately recognized in revenues. Therefore, the adoption of ASC 606 on January 1, 2019 will have no impact on the BMX Agreement. The Company continues to hold ongoing negotiations with a diagnostics company and cannot predict at this time whether the unfulfilled performance obligations and the related unamortized deferred revenues under these arrangements will remain open at January 1, 2019. The Company is continuing to evaluate the impact of the new revenue standard on all of its revenues and costs to obtain or fulfill a contract, including those mentioned above, and its assessment may change in the future based on its ongoing evaluation. In February 2016, the FASB issued ASU No. 2016-02, Leases (Topic 842): Recognition and Measurement of Financial Assets and Financial Liabilities (ASU 2016-02). Under ASU 2016-02, lessees will be required to recognize a lease liability and a right-of-use asset for all leases (with the exception of short term leases) at the commencement date. Lessor accounting under ASU 2016-02 is largely unchanged. ASU 2016-02 is effective for the Company for the year ending December 31, 2020. Early adoption is permitted. Under ASU 2016-02, lessees (for capital and operating leases) and lessors (for sales-type, direct financing and operating leases) must apply a modified retrospective transition approach for leases existing at, or entered into after, the beginning of the earliest comparative period presented in the financial statements. Lessees and lessors may not apply a full retrospective transition approach. The Company is currently evaluating the requirements of ASU 2016-02 and has not yet determined whether adoption of the standard will have a material impact on its consolidated financial statements. In November 2016, the FASB issued ASU No. 2016-18, Statement of Cash Flows (Topic 230): Restricted Cash (ASU 2016-18), requiring restricted cash and cash equivalents to be included in the statement of cash flows. As the Company avails itself of the extended transition period as an emerging growth company under the JOBS Act, the new standard is effective for fiscal years beginning after December 15, 2018 and interim periods within fiscal years beginning after December 15, 2019. Early adoption is permitted in an interim period and any adjustments should be reflected as of the beginning of the fiscal year that includes that interim period. In January 2017, the FASB issued ASU No. 2017-04 Intangibles - Goodwill and Other (Topic 350) - Simplifying the Test for Goodwill Impairment. This ASU eliminates Step 2 from the goodwill impairment test. In addition, income tax effects from any tax deductible goodwill on the carrying amount of the reporting unit should be considered when measuring the goodwill impairment loss, if applicable. The amendments also eliminate the requirements for any reporting unit with a zero or negative carrying amount to perform a qualitative assessment and, if it fails that qualitative test, to perform Step 2 of the goodwill impairment test. An entity still has the option to perform the qualitative assessment for a reporting unit to determine if the quantitative impairment test is necessary. This ASU is effective for annual periods beginning after December 15, 2019 and interim periods within those annual periods. Early adoption is permitted, for interim or annual goodwill impairment tests performed on testing dates after January 1, 2017. The Company does not expect adoption of this ASU to be material to its ongoing financial reporting or on known trends, demands, uncertainties and events in its business. In August 2018, the FASB issued ASU No. 2018-13, “Fair Value Measurement (Topic 820), Disclosure Framework – Changes to the Disclosure Requirements for Fair Value Measurement” . This ASU removed the following disclosure requirements: (1) the amount of and reasons for transfers between Level 1 and Level 2 of the fair value hierarchy; (2) the policy for timing of transfers between levels; and (3) the valuation processes for Level 3 fair value measurements. Additionally, this update added the following disclosure requirements: (1) the changes in unrealized gains and losses for the period included in other comprehensive income for recurring Level 3 fair value measurements held at the end of the reporting period; (2) the range and weighted average of significant unobservable inputs used to develop Level 3 fair value measurements. For certain unobservable inputs, an entity may disclose other quantitative information (such as the median or arithmetic average) in lieu of the weighted average if the entity determines that other quantitative information would be a more reasonable and rational method to reflect the distribution of unobservable inputs used to develop Level 3 fair value measurements. ASU No. 2018-13 will be effective for fiscal years beginning after December 15, 2019 with early adoption permitted. As of September 30, 2018, the Company has not elected to early adopt this guidance but does not expect that the adoption of this guidance will have a material effect on its consolidated financial statements. There have been no other material changes to the significant accounting policies and recent accounting pronouncements previously disclosed in the 2017 Annual Report on Form 10‑K.

Revenue recognition (Tables)

Revenue recognition (Tables)	9 Months Ended
	Sep. 30, 2018
Revenue recognition
Schedule of net revenue by product and service line	Net revenue by product and service line are as follows (in thousands): Three months ended September 30, Nine months ended September 30, 2018 2017 2018 2017 Product revenue Instrument and accessories $ 2,269 $ 1,425 $ 6,043 $ 4,881 Consumable and other product 3,693 1,868 9,864 5,174 Total $ 5,962 $ 3,293 $ 15,907 $ 10,055 Service and other revenue Accelerator and CLIA Lab services $ 1,877 $ 1,408 $ 5,576 $ 3,442 Other services 1,140 764 3,123 1,982 Total $ 3,017 $ 2,172 $ 8,699 $ 5,424
Schedule of total revenue by geography and as a percentage of total revenue	Three months ended September 30, Nine months ended September 30, 2018 2017 2018 2017 North America $ 6,515 62 % $ 3,186 56 % $ 16,138 60 % $ 9,629 59 % EMEA 3,526 33 % 1,867 32 % 8,767 33 % 5,093 31 % Asia Pacific 550 5 % 681 12 % 1,850 7 % 1,563 10 % Total $ 10,591 100 % $ 5,734 100 % $ 26,755 100 % $ 16,285 100 %

Net loss per share (Tables)

Net loss per share (Tables)	9 Months Ended
	Sep. 30, 2018
Net loss per share
Schedule of outstanding potentially dilutive securities that have been excluded in the calculation of diluted net loss per share	September 30, 2018 2017 Redeemable convertible preferred stock — 14,176,012 Unvested restricted common stock and restricted stock units 376,949 226,956 Outstanding stock options 2,565,895 2,291,207 Outstanding warrants 76,041 120,657 Total 3,018,885 16,814,832

Fair value of financial instr_2

Fair value of financial instruments (Tables)	9 Months Ended
	Sep. 30, 2018
Fair value of financial instruments
Schedule of fair value measurements	Fair value measurements as of September 30, 2018 are as follows (in thousands): Quoted Significant prices other Significant in active observable unobservable markets inputs inputs Description Total (Level 1) (Level 2) (Level 3) (unaudited) Financial assets Cash equivalents $ 49,310 $ 49,310 $ — $ — Note receivable 150 — — 150 Total $ 49,460 $ 49,310 $ — $ 150 Fair value measurements as of December 31, 2017 are as follows (in thousands): Quoted Significant prices other Significant in active observable unobservable markets inputs inputs Description Total (Level 1) (Level 2) (Level 3) Financial assets Cash equivalents $ 78,182 $ 78,182 $ — $ — Total $ 78,182 $ 78,182 $ — $ —

Inventory (Tables)

Inventory (Tables)	9 Months Ended
	Sep. 30, 2018
Inventory
Summary of inventory	Inventory consists of the following (in thousands): September 30, December 31, 2018 2017 Raw materials $ 1,660 $ 1,032 Work in process 2,363 968 Finished goods 1,352 1,571 Total $ 5,375 $ 3,571

Investments (Tables)

Investments (Tables)	9 Months Ended
	Sep. 30, 2018
Investments
Roll-forward of the fair value of the Company's convertible note	The below provides a roll-forward of the fair value of the Company’s convertible note, which include Level 3 inputs (in thousands): For the nine months ended September 30, 2018 Beginning Balance — Additions 150 Ending Balance 150

Other accrued expenses (Tables)

Other accrued expenses (Tables)	9 Months Ended
	Sep. 30, 2018
Other accrued expenses
Summary of other accrued expenses	Other accrued expenses consist of the following (in thousands): September 30, December 31, 2018 2017 Accrued inventory $ 542 $ 835 Accrued royalties 251 221 Accrued professional services 580 346 Accrued development costs 1,533 1,559 Accrued other 311 599 Total accrued expenses $ 3,217 $ 3,560

Warrants, stock-based compens_2

Warrants, stock-based compensation, stock options, restricted stock and restricted stock units (Tables)	9 Months Ended
	Sep. 30, 2018
Warrants, stock-based compensation, stock options, restricted stock and restricted stock units
Summary of warrant activity	Weighted average Shares exercise price Warrants outstanding as of December 31, 2017 86,090 9.14 Granted 10,000 21.00 Exercised (20,049) 3.35 Warrants outstanding as of September 30, 2018 76,041 12.23
Summary of share-based compensation expense for all stock awards	Three months ended September 30, Nine months ended September 30, 2018 2017 2018 2017 Cost of product revenue $ 20 $ 7 $ 49 $ 18 Cost of service and other revenue 38 12 121 31 Research and development 152 53 361 126 General and administrative 1,657 551 2,862 1,256 Total $ 1,867 $ 623 $ 3,393 $ 1,431
Summary of stock option activity	Weighted- Remaining Aggregate average contractual intrinsic exercise life value Options price (in years) (in thousands) Outstanding at December 31, 2017 2,249,843 6.05 7.80 $ 34,695 Granted 629,703 $ 18.57 Exercised (234,015) $ 2.92 Cancelled or forfeited (79,624) $ 12.58 Outstanding at September 30, 2018 2,565,907 $ 9.21 7.85 $ 31,368 Vested and expected to vest at September 30, 2018 2,565,907 $ 9.21 7.85 $ 31,368 Exercisable at September 30, 2018 1,160,407 $ 5.22 6.57 $ 18,795
Summary of fair value assumptions of stock options granted to employees and directors for their services on the Company's Board of Directors	Nine months ended September 30, 2018 2017 Risk - free interest rate 2.82 % 2.0 % Expected dividend yield None None Expected term (in years) 5.85 6.0 Expected volatility 34.98 % 51.7 %
Summary of restricted stock activity	Weighted-average grant date fair value Shares per share Unvested restricted common stock as of December 31, 2017 177,192 $ 3.11 Vested (137,386) $ 3.11 Unvested restricted common stock as of September 30, 2018 39,806 $ 3.12
Summary of restricted stock units activity	Weighted-average grant date fair value Shares per share Unvested restricted stock units as of December 31, 2017 — — Granted 393,386 $ 15.60 Unvested restricted stock units as of September 30, 2018 393,386 $ 15.60

Commitments and contingencies (

Commitments and contingencies (Tables)	9 Months Ended
	Sep. 30, 2018
Commitments and contingencies
Schedule of minimum future rent payments under the lease agreement	As of September 30, 2018, the minimum future rent payments under the lease agreements are as follows (in thousands): Years ending December 31: Remainder of 2018 341 2019 1,861 2020 2,618 2021 3,290 2022 and Forward 32,580 $ 40,690

Long Term Debt (Tables)

Long Term Debt (Tables)	9 Months Ended
	Sep. 30, 2018
Long Term Debt
Schedule of debt payment obligations due based on principal payments	Debt payment obligations due based on principal payments are as follows (in thousands): Years ending December 31: Remainder of 2018 0 2019 $ 0 2020 7,687 $ 7,687

Business combinations (Tables)

Business combinations (Tables)	9 Months Ended
	Sep. 30, 2018
Business combinations
Schedule of fair value of consideration transferred	Fair value of consideration transferred: Cash $ 3,200 Obligation to issue cash 800 Total acquisition consideration $ 4,000
Schedule of fair value of assets acquired and liabilities assumed	Fair value of assets acquired and liabilities assumed: Cash and cash equivalents $ 199 Accounts receivable 210 Inventory 828 Prepaid expenses 71 Property and equipment and other non-current assets 180 Intangible Assets 2,950 Goodwill 1,308 Total assets acquired 5,746 Contractual obligations (1,155) Accounts payable and accrued liabilities (591) Net assets acquired $ 4,000

Goodwill and Acquired Intangi_2

Goodwill and Acquired Intangible Assets (Tables)	9 Months Ended
	Sep. 30, 2018
Goodwill and Acquired Intangible Assets
Rollforward of goodwill balance	The following is a rollforward of our goodwill balance (in thousands): Goodwill Balance as of December 31, 2017 $ — Goodwill acquired 1,308 Balance as of September 30, 2018 $ 1,308
Summary of purchased intangible assets	Purchased intangible assets consist of the following (in thousands): Estimated September 30, 2018 Useful Gross Net Life Carrying Accumulated Carrying (in years) Value Amortization Value Developed technology 7 $ 1,650 $ (275) $ 1,375 Customer relationships 10 1,250 (152) 1,098 Trade names 3 50 (11) 39 Total $ 2,950 $ (438) $ 2,512
Schedule of future estimated amortization expense of acquired intangibles	Future estimated amortization expense of acquired intangibles as of September 30, 2018 is as follows (in thousands): Remainder of 2018 $ 164 2019 582 2020 500 2021 403 2022 320 Thereafter 543

Organization and operations (De

Organization and operations (Details) $ / shares in Units, $ in Millions	Dec. 04, 2017	Dec. 31, 2017USD ($)$ / sharesshares	Sep. 30, 2018shares	Dec. 11, 2017shares
Initial Public Offering
Common stock authorized (in shares)		120,000,000	120,000,000	120,000,000
Preferred stock authorized (in shares)		5,000,000	5,000,000	5,000,000
Reverse stock split ratio	0.311
Common stock
Initial Public Offering
Aggregate net proceeds from IPO | $		$ 65.6
Reverse stock split ratio	0.311
Initial Public Offering
Initial Public Offering
Preferred stock converted to common stock (in shares)		14,185,744
Carrying value of preferred stock, notes and warrants reclassified as common stock and additional paid-in capital | $		$ 143.3
Initial Public Offering | Common stock
Initial Public Offering
Number of shares issued		4,916,480
Shares issued (in dollars per share) | $ / shares		$ 15

Revenue recognition (Details)

Revenue recognition (Details) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018USD ($)	Sep. 30, 2017USD ($)	Sep. 30, 2018USD ($)item	Sep. 30, 2017USD ($)
Revenue recognition
Number of bi-annual preventative maintenance visits included in implied warranty and extended service contracts | item			2
Term of average selling prices used to determine estimate of current sales price			12 months
Total revenue	$ 10,591	$ 5,734	$ 26,755	$ 16,285
Revenue by region as a percentage of total revenue	100.00%	100.00%	100.00%	100.00%
North America
Revenue recognition
Total revenue	$ 6,515	$ 3,186	$ 16,138	$ 9,629
Revenue by region as a percentage of total revenue	62.00%	56.00%	60.00%	59.00%
EMEA
Revenue recognition
Total revenue	$ 3,526	$ 1,867	$ 8,767	$ 5,093
Revenue by region as a percentage of total revenue	33.00%	32.00%	33.00%	31.00%
Asia Pacific
Revenue recognition
Total revenue	$ 550	$ 681	$ 1,850	$ 1,563
Revenue by region as a percentage of total revenue	5.00%	12.00%	7.00%	10.00%
Products
Revenue recognition
Total revenue	$ 5,962	$ 3,293	$ 15,907	$ 10,055
Instrument and accessories
Revenue recognition
Standard warranty period			1 year
Implied warranty period			1 year
Total revenue	2,269	1,425	$ 6,043	4,881
Consumable and other product
Revenue recognition
Total revenue	3,693	1,868	9,864	5,174
Service and other
Revenue recognition
Total revenue	3,017	2,172	8,699	5,424
Accelerator and CLIA Lab services
Revenue recognition
Total revenue	1,877	1,408	5,576	3,442
Other services
Revenue recognition
Total revenue	1,140	764	3,123	1,982
Collaboration and license
Revenue recognition
Total revenue	$ 1,612	$ 269	$ 2,149	$ 806

Net loss per share (Details)

Net loss per share (Details)	Dec. 04, 2017	Sep. 30, 2018shares	Sep. 30, 2017shares
Net loss per share
Number of dilutive securities excluded in the calculation of diluted net loss per share		3,018,885	16,814,832
Reverse stock split ratio	0.311
Common stock
Net loss per share
Obligation to issue warrants, in shares		93,341	93,341
Series A3 Preferred Stock
Net loss per share
Obligation to issue warrants, in shares		300,000	300,000
Redeemable convertible preferred stock
Net loss per share
Number of dilutive securities excluded in the calculation of diluted net loss per share			14,176,012
Unvested restricted common stock and restricted stock units
Net loss per share
Number of dilutive securities excluded in the calculation of diluted net loss per share		376,949	226,956
Stock options
Net loss per share
Number of dilutive securities excluded in the calculation of diluted net loss per share		2,565,895	2,291,207
Warrants
Net loss per share
Number of dilutive securities excluded in the calculation of diluted net loss per share		76,041	120,657

Fair value measurements (Detail

Fair value measurements (Details) - USD ($) $ in Thousands	Sep. 30, 2018	Dec. 31, 2017
Financial Instruments, Financial Assets, Balance Sheet Groupings [Abstract]
Cash equivalents	$ 49,310	$ 78,182
Note receivable	150
Total financial assets	49,460	78,182
Level 1
Financial Instruments, Financial Assets, Balance Sheet Groupings [Abstract]
Cash equivalents	49,310	78,182
Total financial assets	49,310	$ 78,182
Level 3
Financial Instruments, Financial Assets, Balance Sheet Groupings [Abstract]
Note receivable	150
Total financial assets	$ 150

Inventory (Details)

Inventory (Details) - USD ($) $ in Thousands	Sep. 30, 2018	Dec. 31, 2017
Inventory
Raw materials	$ 1,660	$ 1,032
Work in process	2,363	968
Finished goods	1,352	1,571
Total	$ 5,375	$ 3,571

Investments (Details)

Investments (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2018	Sep. 30, 2016
Minority interest in preferred stock in privately held company
Schedule of Cost-method Investments [Line Items]
Purchase price of investment		$ 300
Impairment on investments	$ 0
Investment in a convertible notes of a privately held company
Schedule of Cost-method Investments [Line Items]
Investment principle amount	200
Investment in a convertible notes of a privately held company | Level 3
Roll-forward of fair value of convertible note
Additions	150
Ending Balance	$ 150

Other accrued expenses (Details

Other accrued expenses (Details) - USD ($) $ in Thousands	Sep. 30, 2018	Dec. 31, 2017
Other accrued expenses
Accrued inventory	$ 542	$ 835
Accrued royalties	251	221
Accrued professional services	580	346
Accrued development costs	1,533	1,559
Accrued other	311	599
Total accrued expenses	$ 3,217	$ 3,560

Redeemable convertible prefer_2

Redeemable convertible preferred stock (Details)	Dec. 04, 2017	Sep. 30, 2018shares	Dec. 31, 2017shares	Dec. 11, 2017shares
Redeemable convertible preferred stock.
Preferred stock authorized (in shares)		5,000,000	5,000,000	5,000,000
Preferred stock conversion ratio	0.311

Warrants, stock-based compens_3

Warrants, stock-based compensation, stock options, restricted stock and restricted stock units - Warrants (Details) - Warrants	9 Months Ended
	Sep. 30, 2018$ / sharesshares
Number outstanding
Outstanding at the beginning of the period (in shares) | shares	86,090
Granted (in shares) | shares	10,000
Exercised (in shares) | shares	(20,049)
Outstanding at the end of the period (in shares) | shares	76,041
Weighted average exercise price
Outstanding at the beginning of the period (in dollars per share) | $ / shares	$ 9.14
Granted (in dollars per share) | $ / shares	21
Exercised (in dollars per share) | $ / shares	3.35
Outstanding at the end of the period (in dollars per share) | $ / shares	$ 12.23

Warrants, stock-based compens_4

Warrants, stock-based compensation, stock options, restricted stock and restricted stock units - Share-based compensation expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Common stock, restricted stock, stock options, restricted stock units and warrants
Share-based compensation expense	$ 1,867	$ 623	$ 3,393	$ 1,431
Cost of product revenue
Common stock, restricted stock, stock options, restricted stock units and warrants
Share-based compensation expense	20	7	49	18
Cost of service and other revenue
Common stock, restricted stock, stock options, restricted stock units and warrants
Share-based compensation expense	38	12	121	31
Research and development
Common stock, restricted stock, stock options, restricted stock units and warrants
Share-based compensation expense	152	53	361	126
General and administrative
Common stock, restricted stock, stock options, restricted stock units and warrants
Share-based compensation expense	$ 1,657	$ 551	$ 2,862	$ 1,256

Warrants, stock-based compens_5

Warrants, stock-based compensation, stock options, restricted stock and restricted stock units - Stock-based award plans (Details) - shares	Jan. 01, 2018	Sep. 30, 2018	Dec. 31, 2017
2007 Plan
Common stock, restricted stock, stock options, restricted stock units and warrants
Common stock available for future awards (in shares)		0
2017 Plan
Common stock, restricted stock, stock options, restricted stock units and warrants
Shares authorized under the plan (in shares)			1,042,314
Shares available for grant under the plan (in shares)		110,223
Annual increase in the shares available for grant under the plan (as a percent of shares of common stock outstanding)		4.00%
2017 ESPP
Common stock, restricted stock, stock options, restricted stock units and warrants
Shares authorized under the plan (in shares)		427,305
Shares available for grant under the plan (in shares)		427,305
Annual increase in the shares available for grant under the plan (as a percent of shares of common stock outstanding)		1.00%
Increase in the shares available for grant under the plan (in shares)	218,842
Stock options
Common stock, restricted stock, stock options, restricted stock units and warrants
Options outstanding (in shares)		2,565,907	2,249,843
Stock options | 2007 Plan
Common stock, restricted stock, stock options, restricted stock units and warrants
Options outstanding (in shares)		2,015,828
Common stock issued and outstanding pursuant to the exercise of options (in shares)		805,853
Stock options | 2017 Plan
Common stock, restricted stock, stock options, restricted stock units and warrants
Shares authorized under the plan (in shares)			2,490,290
Restricted and unrestricted stock awards | 2007 Plan
Common stock, restricted stock, stock options, restricted stock units and warrants
Common stock issued and outstanding pursuant to restricted or unrestricted stock awards (in shares)		1,128,975

Warrants, stock-based compens_6

Warrants, stock-based compensation, stock options, restricted stock and restricted stock units - Stock options (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Dec. 31, 2017
Aggregate intrinsic value
Share-based compensation expense	$ 1,867	$ 623	$ 3,393	$ 1,431
Stock options
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Options expiration period (in years)			10 years
Number outstanding
Outstanding at the beginning of the period (in shares)			2,249,843
Granted (in shares)			629,703
Exercised (in shares)			(234,015)
Cancelled or forfeited (in shares)			(79,624)
Outstanding at the end of the period (in shares)	2,565,907		2,565,907		2,249,843
Vested and expected to vest at the end of the period (in shares)	2,565,907		2,565,907
Exercisable at the end of the period (in shares)	1,160,407		1,160,407
Weighted-average exercise price
Outstanding at the beginning of the period (in dollars per share)			$ 6.05
Granted (in dollars per share)			18.57
Exercised (in dollars per share)			2.92
Cancelled or forfeited (in dollars per share)			12.58
Outstanding at the end of the period (in dollars per share)	$ 9.21		9.21		$ 6.05
Vested and expected to vest at the end of the period (in dollars per share)	9.21		9.21
Exercisable at the end of the period (in dollars per share)	$ 5.22		$ 5.22
Remaining contractual life
Outstanding (in years)			7 years 10 months 6 days		7 years 9 months 18 days
Vested and expected to vest at the end of the period (in years)			7 years 10 months 6 days
Exercisable at the end of the period (in years)			6 years 6 months 26 days
Aggregate intrinsic value
Outstanding	$ 31,368		$ 31,368		$ 34,695
Vested and expected to vest at the end of the period	31,368		31,368
Exercisable at the end of the period	18,795		$ 18,795
Weighted-average fair value of options granted			$ 7.32	$ 4.50
Share-based compensation expense	700	400	$ 1,800	$ 900
Intrinsic value of stock options exercised	600		3,400	$ 200
Total unrecognized compensation cost related to unvested stock options	$ 7,100		$ 7,100
Period of recognition of unrecognized compensation cost			2 years 9 months 22 days
Fair value assumptions
Risk-free interest rate (as a percent)			2.82%	2.00%
Expected dividend yield (as a percent)			0.00%	0.00%
Expected term (in years)			5 years 10 months 6 days	6 years
Expected volatility (as a percent)			34.98%	51.70%
Stock options | Maximum
Aggregate intrinsic value
Intrinsic value of stock options exercised		$ 100
Subject to a four year vesting schedule with 25% vesting on the first anniversary and the remaining vesting ratably on a monthly basis over the remaining three years | Stock options
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Vesting period (in years)			4 years
Vesting percentage 1 (as a percent)			25.00%
Subject to vesting with 50% vesting on December 31, 2018 and December 31, 2019 | Stock options
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Vesting period (in years)			3 years
Vesting percentage 1 (as a percent)			75.00%

Warrants, stock-based compens_7

Warrants, stock-based compensation, stock options, restricted stock and restricted stock units - Restricted stock (Details) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended		3 Months Ended		9 Months Ended
	Jan. 31, 2015	Dec. 31, 2014	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Weighted-average grant date fair value per share
Share-based compensation expense			$ 1,867	$ 623	$ 3,393	$ 1,431
Restricted stock
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)					0
Number of restricted stock
Unvested restricted common stock at the beginning of the period (in shares)					177,192
Vested (in shares)					(137,386)
Unvested restricted common stock at the end of the period (in shares)			39,806		39,806
Weighted-average grant date fair value per share
Unvested restricted common stock at the beginning of the period (in dollars per share)					$ 3.11
Vested (in dollars per share)					3.11
Unvested restricted common stock at the end of the period (in dollars per share)			$ 3.12		$ 3.12
Share-based compensation expense			$ 100	$ 200	$ 400	$ 500
Total unrecognized compensation cost related to unvested stock awards			$ 0		$ 0
Period of recognition of unrecognized compensation cost					0 years
Aggregate fair value of restricted stock awards					$ 1,900
2007 Plan | Restricted stock | Director
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)		78,912
Vesting period (in years)		4 years
2007 Plan | Restricted stock | Executive
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)	781,060
Vesting period (in years)	4 years
2007 Plan | Restricted stock | Executive | Subject to a four year vesting schedule with 25% vesting on the first anniversary and the remaining vesting ratably on a monthly basis over the remaining three years
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Vesting percentage 1 (as a percent)	25.00%
2007 Plan | Restricted stock | Executive | Subject to vesting with 50% vesting on December 31, 2018 and December 31, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Vesting period (in years)	3 years
Vesting percentage 1 (as a percent)	75.00%

Warrants, stock-based compens_8

Warrants, stock-based compensation, stock options, restricted stock and restricted stock units - Restricted stock units (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Weighted-average grant date fair value per share
Share-based compensation expense	$ 1,867	$ 623	$ 3,393	$ 1,431
Restricted stock units
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)			393,386
Number of restricted stock units
Granted (in shares)			393,386
Unvested restricted common stock at the end of the period (in shares)	393,386		393,386
Weighted-average grant date fair value per share
Granted (in dollars per share)			$ 15.60
Unvested restricted common stock at the end of the period (in dollars per share)	$ 15.60		$ 15.60
Share-based compensation expense	$ 1,100		$ 1,200
Total unrecognized compensation cost related to unvested stock awards	$ 5,000		$ 5,000
Period of recognition of unrecognized compensation cost			3 years 1 month 17 days
2017 Plan | Restricted stock units | Subject to a four year vesting schedule with 25% vesting on the first anniversary and the remaining vesting ratably on a monthly basis over the remaining three years
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)			56,196
Vesting period 1			4 years
Vesting period 2			3 years
Vesting percentage 1 (as a percent)			25.00%
Vesting percentage 2 (as a percent)			75.00%
Number of restricted stock units
Granted (in shares)			56,196
2017 Plan | Restricted stock units | Subject to vesting with 50% vesting on December 31, 2018 and December 31, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)			18,200
Vesting percentage 1 (as a percent)			50.00%
Vesting percentage 2 (as a percent)			50.00%
Number of restricted stock units
Granted (in shares)			18,200
2017 Plan | Restricted stock units | Subject to a four year vesting schedule with 25% vesting on each anniversary
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)			3,100
Vesting period 1			4 years
Vesting percentage 1 (as a percent)			25.00%
Number of restricted stock units
Granted (in shares)			3,100
2017 Plan | Restricted stock units | Vesting on December 31, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)			15,890
Number of restricted stock units
Granted (in shares)			15,890
2017 Plan | Restricted stock units | Vested on August 31, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)			50,000
Number of restricted stock units
Granted (in shares)			50,000
2017 Plan | Restricted stock units | Vests evenly over 40 months on the last day of each month starting September 30,2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Restricted common stock issued (in shares)			250,000
Vesting period 3			40 months
Number of restricted stock units
Granted (in shares)			250,000

Commitments and contingencies -

Commitments and contingencies - License agreements and Lease commitments (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Aug. 31, 2018
Minimum future rent payments under the lease agreement
Remainder of 2018	$ 341		$ 341
2,019	1,861		1,861
2,020	2,618		2,618
2,021	3,290		3,290
2022 and Forward	32,580		32,580
Total	40,690		40,690
Rent expense	400	$ 200	1,000	$ 800
Tufts
License agreements
Royalty expense	200	100	500	300
Other licenses
License agreements
Royalty expense	100			$ 200
Annual minimum royalty to be paid under the license agreement	50		50
Other licenses | Maximum
License agreements
Royalty expense		$ 100	300
Lease for facilities in Billerica, Massachusetts | Aushon
Lease commitments
Consideration for the early termination					$ 75,933
Other non-current liabilities | Maximum
Lease commitments
Deferred rent expense	100		100
Other accrued expenses | Maximum
Lease commitments
Deferred rent expense	$ 100		$ 100

Commitments and contingencies_2

Commitments and contingencies - Development and supply agreement and Legal contingencies (Details) - STRATEC Biomedical - Development and supply agreement $ / shares in Units, $ in Millions	9 Months Ended
	Sep. 30, 2018USD ($)$ / sharesshares
Commitments and contingencies
Amount payable to counterparty	$ 1.5
Period to purchase minimum number of commercial units	7 years
Fee payable on shortfall of commercial units purchase	$ 11.6
Issuance of supply warrants on termination of agreement, number (in shares) | shares	93,341
Issuance of supply warrants on termination of agreement, value per share (in dollars per share) | $ / shares	$ 0.003214

Long Term Debt (Details)

Long Term Debt (Details) - USD ($) $ in Thousands	3 Months Ended			9 Months Ended
	Sep. 30, 2018	Aug. 31, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Debt payment obligations due based on principal payments
Remainder of 2018	$ 0			$ 0
2,019	0			0
2,020	7,687			7,687
Debt payment obligations	7,687			7,687
Non-cash interest expense	0		$ 100	100	$ 200
Loan agreement
Long Term Debt
Additional amounts available to borrow	$ 0			0
Term charge				500
Repayments of principal amount		$ 0		$ 1,400
Loan agreement | Minimum
Long Term Debt
Interest rate (as a percent)	8.00%			8.00%
Prime rate | Loan agreement
Long Term Debt
Margin on variable interest rate (as a percent)				(5.25%)

Collaboration and license arr_2

Collaboration and license arrangements (Details) $ in Thousands	Sep. 06, 2018USD ($)	Dec. 31, 2016USD ($)	Sep. 30, 2018USD ($)	Sep. 30, 2017USD ($)	Sep. 30, 2018USD ($)	Sep. 30, 2017USD ($)	Dec. 31, 2015USD ($)agreementitem	Dec. 31, 2017USD ($)
Collaboration and license arrangements
Revenues recognized			$ 10,591	$ 5,734	$ 26,755	$ 16,285
Joint development and license agreement
Collaboration and license arrangements
Consideration on collaboration activities					3,200
Revenues recognized	$ 1,600		1,600	$ 300	2,100	$ 800
Evaluation and option agreements and license agreement
Collaboration and license arrangements
Revenues recognized		$ 1,800
Deferred revenue			$ 1,200		$ 1,200			$ 1,200
Number of agreements | agreement							3
Number of fields for which the agreements were entered | item							3
Non-refundable license fee		1,000					$ 2,000
Amount allocated to the option of the related field		$ 800

Business combinations (Details)

Business combinations (Details) - USD ($) $ in Thousands	Jan. 30, 2018	Jul. 31, 2018	Sep. 30, 2018
Fair value of assets acquired and liabilities assumed:
Goodwill			$ 1,308
Aushon acquisition
Fair value of consideration transferred
Cash	$ 3,200	$ 800
Obligation to issue cash	800
Total acquisition consideration	4,000
Fair value of assets acquired and liabilities assumed:
Cash and cash equivalents	199
Accounts receivable	210
Inventory	828
Prepaid expenses	71
Property and equipment and other non-current assets	180
Intangible Assets	2,950
Goodwill	1,308
Total assets acquired	5,746
Contractual obligations	(1,155)
Accounts payable and accrued liabilities	(591)
Net assets acquired	$ 4,000
Risk-adjusted discount rate used to determine fair value of intangible assets	14.40%
Transaction costs			$ 100

Goodwill and Acquired Intangi_3

Goodwill and Acquired Intangible Assets (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Rollforward of goodwill balance
Goodwill acquired			$ 1,308
Balance as of end of period	$ 1,308		1,308
Purchased intangible assets
Gross Carrying Value	2,950		2,950
Accumulated Amortization	(438)		(438)
Net Carrying Value	2,512		2,512
Amortization expense	200	$ 0	400	$ 0
Future estimated amortization expense
Remainder of 2018	164		164
2,019	582		582
2,020	500		500
2,021	403		403
2,022	320		320
Thereafter	543		$ 543
Developed technology
Purchased intangible assets
Estimated Useful Life			7 years
Gross Carrying Value	1,650		$ 1,650
Accumulated Amortization	(275)		(275)
Net Carrying Value	1,375		$ 1,375
Customer relationships
Purchased intangible assets
Estimated Useful Life			10 years
Gross Carrying Value	1,250		$ 1,250
Accumulated Amortization	(152)		(152)
Net Carrying Value	1,098		$ 1,098
Trade names
Purchased intangible assets
Estimated Useful Life			3 years
Gross Carrying Value	50		$ 50
Accumulated Amortization	(11)		(11)
Net Carrying Value	$ 39		$ 39

Related party transactions (Det

Related party transactions (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Dec. 31, 2017
bioMerieux | Joint development and license agreement
Related party transactions
Related party revenue	$ 1.6	$ 0.3	$ 2.1	$ 0.8
Deferred revenue	0		0		$ 2.1
Tufts | License Agreement
Related party transactions
Royalty expense	0.2	$ 0.1	0.5	$ 0.3
Harvard University | Maximum
Related party transactions
Related party revenue	$ 0.1		$ 0.1

Subsequent events (Details)

Subsequent events (Details) - Company headquarters - Subsequent event	Oct. 02, 2018USD ($)item
Subsequent events
Term of operating lease	137 months
Square footage of office and laboratory space | item	92,000
Monthly rent	$ 272,000
Percentage of annual increase in rent expense for years 1-5	2.50%
Percentage of annual increase in rent expense after years 1-5	3.00%
Free rent period of lease	5 months
NNN costs paid during free rent period	$ 0
Percentage of reduced rent to the stated rent amount, 13 months thereafter	50.00%
Percentage of NNN costs payable, 13 months thereafter	100.00%
Letter of Credit
Subsequent events
Drawing capacity	$ 1,000,000
Letter of Credit from 41 months
Subsequent events
Drawing capacity	750,000
Letter of Credit from 65 months
Subsequent events
Drawing capacity	$ 250,000