(3) | Pursuant to Rule 415(a)(6) under the Securities Act, the securities registered pursuant to this registration statement include $120,000,196 of unsold securities (the “Carry Forward Securities”) previously registered pursuant to the shelf registration statement on Form S-3 (File No. 333-254603), which was declared effective by the U.S. Securities and Exchange Commission on March 17, 2021 (the “Prior Registration Statement”). The Carry Forward Securities do not include $7,773,713.97 of securities that are available for sale under the Prior Registration Statement as of the filing of this registration statement, which amount may be sold under the Prior Registration Statement in the Company’s at-the-market offering or in another offering under the Prior Registration Statement at any time or from time to time prior to the expiration of the Prior Registration Statement on March 17, 2024. In connection with the filing of the Prior Registration Statement, the registrant paid a filing fee of $16,365. Of this amount, $13,092.02 is associated with the Carry Forward Securities. The filing fees associated with the Carry Forward Securities is hereby carried forward to be applied to the Carry Forward Securities registered hereunder, and no additional filing fee is due with respect to the Carry Forward Securities in connection with the filing of this registration statement. To the extent that, after the filing date hereof and prior to the effectiveness of this registration statement, the registrant sells any Carry Forward Securities pursuant to the Prior Registration Statement, the registrant will identify in a pre-effective amendment to this registration statement the updated number of Carry Forward Securities from the Prior Registration Statement to be included in this registration statement pursuant to Rule 415(a)(6) and the updated amount of new securities to be registered on this registration statement. Pursuant to Rule 415(a)(6), the offering of the Carry Forward Securities under the Prior Registration Statement will be deemed terminated as of the date of effectiveness of this registration statement. |