AXIM Biotechnologies (AXIM) 10-Q 22 Nov 21 2021 Q3 Quarterly report Financial data

Cover

Cover - shares	9 Months Ended
	Sep. 30, 2021	Nov. 19, 2021
Cover [Abstract]
Entity Registrant Name	AXIM Biotechnologies, Inc.
Entity Central Index Key	0001514946
Document Type	10-Q
Amendment Flag	false
Current Fiscal Year End Date	--12-31
Entity Small Business	true
Entity Shell Company	false
Entity Emerging Growth Company	false
Entity Current Reporting Status	Yes
Document Period End Date	Sep. 30, 2021
Entity Filer Category	Non-accelerated Filer
Document Fiscal Period Focus	Q3
Document Fiscal Year Focus	2021
Entity Common Stock Shares Outstanding		136,178,104
Document Quarterly Report	true
Document Transition Report	false
Entity Interactive Data Current	No
Entity Ex Transition Period	false
Entity File Number	000-54296
Entity Incorporation State Country Code	NV
Entity Tax Identification Number	27-4029386
Entity Address Address Line 1	6191 Cornerstone Court
Entity Address Address Line 2	E. Suite 114
Entity Address City Or Town	San Diego
Entity Address State Or Province	CA
Entity Address Postal Zip Code	92121
City Area Code	858
Local Phone Number	923-4422

CONDENSED CONSOLIDATED BALANCE

CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited) - USD ($)	Sep. 30, 2021	Dec. 31, 2020
Current assets:
Cash	$ 338,377	$ 457,181
Prepaid expenses	141,542	255,923
Inventory	20,127	0
Total current assets	500,046	713,104
Property and equipment, net of accumulated depreciation	103,997	104,094
Other Assets:
Notes receivable- related party	104,012	103,242
Patents (net of accumulated amortization of $2042 and $0; respectively)	247,958	0
Licenses (net of accumulated amortization of $35,474 and $0; respectively)	4,234,526	0
Goodwill	2,458,233	2,458,233
Intellectual Property and In-Process Research (net of accumulated amortization of $1,296,438 and $0; respectively)	6,503,562	7,800,000
Security deposit	5,000	5,000
Operating lease right-of-use asset	90,630	130,722
Total other assets	13,643,921	10,497,197
TOTAL ASSETS	14,247,964	11,314,395
Current liabilities:
Accounts payable and accrued liabilities	931,819	1,073,142
Lease liability obligations	58,540	53,851
Due to shareholder	180	180
Due to first insurance funding	65,880	25,369
Promissory note (including accrued interest of $34,222 and $19,507, respectively) (see note 8)	538,440	343,725
Total current liabilities	1,594,859	1,496,267
Long-term liabilities:
Deferred tax liability	2,340,000	2,340,000
Convertible note payable (including accrued interest of $208,089 and $236,148, respectively) net of unamortized debt discount of $623,095 and $843,673, respectively(see note 11)	1,369,307	1,676,788
Convertible note payable - related party (including accrued interest of $264,037 and $158,648, respectively)	4,264,037	4,158,648
Lease liability obligations	32,090	76,871
Other liabilities of discontinued operations	0	0
Total long-term liabilities	8,005,434	8,252,307
TOTAL LIABILITIES	9,600,293	9,748,574
STOCKHOLDERS' DEFICIT
Common stock, $0.0001 par value, 300,000,000 shares authorized 135,885,104 and 125,327,579 shares issued and outstanding, respectively	13,589	12,533
Additional paid in capital	50,009,591	43,201,186
Common stock to be issued	4,457,500	201,974
Accumulated deficit	(49,833,059)	(41,849,922)
TOTAL STOCKHOLDERS' DEFICIT	4,647,671	1,565,821
TOTAL LIABILITIES AND STOCKHOLDERS' DEFICIT	14,247,964	11,314,395
Convertible Preferred Stock Series C
STOCKHOLDERS' DEFICIT
Preferred Stock, Value	$ 50	$ 50

CONDENSED CONSOLIDATED BALANC_2

CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited) (Parenthetical) - USD ($)	Sep. 30, 2021	Dec. 31, 2020
Preferred Stock, Par or Stated Value Per Share	$ 0.0001	$ 0.0001
Preferred Stock, Shares Authorized	5,000,000	5,000,000
Common Stock, Par or Stated Value Per Share	$ 0.0001	$ 0.0001
Common Stock, Shares Authorized	300,000,000	300,000,000
Common Stock, Shares, Issued	135,885,104	125,327,579
Common Stock, Shares, Outstanding	135,885,104	125,327,579
Unamortized debt discount	$ 623,095	$ 843,673
Convertible Preferred Stock SeriesB [Member]
Preferred Stock, Par or Stated Value Per Share	$ 0.0001	$ 0.0001
Preferred Stock, Shares Authorized	500,000	500,000
Preferred Stock, Shares Issued	0	0
Preferred Stock, Shares Outstanding	0	0
Convertible Preferred Stock Series C
Preferred Stock, Par or Stated Value Per Share	$ 0.0001	$ 0.0001
Preferred Stock, Shares Authorized	500,000	500,000
Preferred Stock, Shares Issued	500,000	500,000
Preferred Stock, Shares Outstanding	500,000	500,000
Promissory note - related party
Interest Payable, Current	$ 34,222	$ 19,507
Convertible note payable
Interest Payable, Current	208,089	236,148
Unamortized debt discount	623,095	843,673
Convertible note payable - related party
Interest Payable, Current	$ 264,037	$ 158,648

UNAUDITED CONDENSED CONSOLIDATE

UNAUDITED CONDENSED CONSOLIDATED STATEMENT OF OPERATIONS - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
UNAUDITED CONDENSED CONSOLIDATED STATEMENT OF OPERATIONS
Revenues	$ 8,127	$ 0	$ 55,651	$ 0
Operating Expenses:
Research and development expenses	67,263	109,139	216,282	235,431
Selling, general and administrative	2,519,527	1,184,267	4,812,790	2,442,420
Amortization of other assets	692,858	0	1,333,954	0
Depreciation	6,935	5,372	20,119	10,497
Total operating expenses from continuing operations	3,286,583	1,298,778	6,383,145	2,688,348
Loss from continuing operations	(3,278,456)	(1,298,778)	(6,327,494)	(2,688,348)
Other (income) expenses:
Interest income	(256)	(260)	(769)	(419)
Income from Grants from Government	(59,986)	(25,899)	(279,981)	(25,899)
Unrealized loss (gain) on marketable securities	0	0	0	104,705
Realized loss (gain) on marketable securities	0	0	0	109,040
Amortization of note discount	17,456	22,313	220,578	63,745
Loss on Extinguishment of Debt	0	923,604	1,535,264	923,604
Interest expense	56,007	73,268	175,915	179,344
Total other (income) expenses	13,221	993,026	1,651,007	1,354,120
Loss before provision of income tax	(3,291,677)	(2,291,804)	(7,978,501)	(4,042,468)
Provision for income tax	0	0	0	0
Income (loss) from continuing operations	(3,291,677)	(2,291,804)	(7,978,501)	(4,042,468)
Income (loss) from discontinued operations	0	386,237	(4,633)	29,144
NET LOSS	(3,291,677)	(1,905,567)	(7,983,134)	(4,013,324)
NET LOSS ATTRIBUTABLE TO COMMON SHAREHOLDERS	$ (3,291,677)	$ (1,905,567)	$ (7,983,134)	$ (4,013,324)
Earning per share from continuing operations
Basic	$ (0.02)	$ (0.02)	$ (0.06)	$ (0.04)
Diluted	(0.02)	(0.02)	(0.06)	(0.04)
Earning per share from discontinued operations
Basic	0	0	0	0
Diluted	0	0	0	0
Earning per share
Basic	(0.02)	(0.02)	(0.06)	(0.04)
Diluted	$ (0.02)	$ (0.02)	$ (0.06)	$ (0.04)
Weighted average common shares outstanding - basic and diluted	133,663,974	123,496,143	129,803,948	105,383,791

Unaudited Condensed Consolida_2

Unaudited Condensed Consolidated Statement of Stockholders' Deficit - USD ($)	Total	Common Stock	Preferred Stock	Series A, Preferred Stock	Series B, Preferred Stock	Series C, Preferred Stock	Common Stock To Be Issued	Additional Paid-In Capital	Subscription Amount Receivable	Accumulated Deficit
Balance, shares at Dec. 31, 2019		64,854,539			500,000	500,000
Balance, amount at Dec. 31, 2019	$ (6,760,397)	$ 6,486	$ 0	$ 0	$ 50	$ 50	$ 50,000	$ 28,623,060	$ 0	$ (35,440,042)
Common stock to be issued for Note receivable and True-up adjustment	0
Common stock issued against common stock to be issued received in PY, shares		250,000
Common stock issued against common stock to be issued received in PY, amount	0	$ 25					(50,000)	49,975
Common stock issued for services, shares		662,839
Common stock issued for services, amount	287,500	$ 66						287,434
Common stock issued under registration statement on Form S-3, shares		3,541,667
Common stock issued under registration statement on Form S-3, amount	962,500	$ 355						962,145
Subscription price adjustment	(518,948)							(518,948)
Beneficial conversion of 190K convertible note	190,000							190,000
Common stock issued for acquisition, shares		54,000,000
Common stock issued for acquisition, amount	7,506,000	$ 5,400						7,500,600
Net loss	(2,028,367)									(2,028,367)
Balance, shares at Mar. 31, 2020		123,309,045			500,000	500,000
Balance, amount at Mar. 31, 2020	(361,712)	$ 12,331	0	0	$ 50	$ 50	0	37,094,266	0	(37,468,409)
Balance, shares at Dec. 31, 2019		64,854,539			500,000	500,000
Balance, amount at Dec. 31, 2019	(6,760,397)	$ 6,486	0	0	$ 50	$ 50	50,000	28,623,060	0	(35,440,042)
Common stock issued for services, amount	302,000
Net loss	(4,013,324)
Balance, shares at Sep. 30, 2020		125,196,970				500,000
Balance, amount at Sep. 30, 2020	2,287,497	$ 12,519	0	0	$ 0	$ 50	135,000	41,593,293	0	(39,453,365)
Balance, shares at Mar. 31, 2020		123,309,045			500,000	500,000
Balance, amount at Mar. 31, 2020	(361,712)	$ 12,331	0	0	$ 50	$ 50	0	37,094,266	0	(37,468,409)
Common stock to be issued for Note receivable and True-up adjustment	135,000						135,000
Common stock issued under registration statement on Form S-3, shares		3,953,125
Common stock issued under registration statement on Form S-3, amount	548,000	$ 395						547,605
Subscription price adjustment	(90,887)							(90,887)
Net loss	(79,389)									(79,389)
Common stock issued for severance, shares		477,025
Common stock issued for severance, amount	150,000	$ 48						149,952
Common stock issued per stock purchase agreement, shares		3,975,383
Common stock issued per stock purchase agreement, amount	700,000	$ 397						699,603
Series B preferred stock retirement, shares					(500,000)
Series B preferred stock retirement, amount	(50)				$ (50)
Retired common stock, shares		(18,570,356)
Retired common stock, amount	(1,857)	$ (1,857)
Balance, shares at Jun. 30, 2020		113,144,222				500,000
Balance, amount at Jun. 30, 2020	999,105	$ 11,314	0	0	0	$ 50	135,000	38,400,539	0	(37,547,798)
Common stock issued for services, shares		773,943
Common stock issued for services, amount	378,690	$ 77						378,613
Net loss	(1,905,567)									(1,905,567)
Common stock issued for severance, shares		314,852
Common stock issued for severance, amount	255,000	$ 32						254,968
Common stock issued per stock purchase agreement, shares		5,822,576
Common stock issued per stock purchase agreement, amount	1,098,630	$ 582						1,098,048
Convertible note converted to common stock, shares		5,141,377
Convertible note converted to common stock, amount	51,414	$ 514						50,900
Stock based compensation - stock options	414,839							414,839
Loss on extinguishment of debt	823,497							823,497
Loss on conversion of convertible note	171,889							171,889
Balance, shares at Sep. 30, 2020		125,196,970				500,000
Balance, amount at Sep. 30, 2020	2,287,497	$ 12,519	0	0	0	$ 50	135,000	41,593,293	0	(39,453,365)
Balance, shares at Dec. 31, 2020		125,327,579				500,000
Balance, amount at Dec. 31, 2020	1,565,821	$ 12,533	0	0	0	$ 50	201,974	201,974	43,201,186	(41,849,922)
Common stock to be issued for Note receivable and True-up adjustment	0
Common stock issued against common stock to be issued received in PY, shares		108,965
Common stock issued against common stock to be issued received in PY, amount	0	$ 11					(66,974)	66,963
Net loss	(864,536)									(864,536)
Stock based compensation - stock options	99,742							99,742
Common stock to be issued for purchase of shares	168,500						168,500
Common stock issued for severance payable of discontinued operation, shares		379,463
Common stock issued for severance payable of discontinued operation, amount	225,001	$ 38						224,963
Common stock issued for cash, shares		1,712,500
Common stock issued for cash, amount	434,000	$ 171						433,829
Balance, shares at Mar. 31, 2021		127,528,507				500,000
Balance, amount at Mar. 31, 2021	1,628,528	$ 12,753	0	0	0	$ 50	303,500	44,026,683	0	(42,714,458)
Balance, shares at Dec. 31, 2020		125,327,579				500,000
Balance, amount at Dec. 31, 2020	1,565,821	$ 12,533	0	0	0	$ 50	201,974	201,974	43,201,186	(41,849,922)
Common stock issued for services, amount	$ 0
Common stock issued under registration statement on Form S-3, shares	175,000
Common stock issued under registration statement on Form S-3, amount	$ 52,500
Net loss	(7,983,134)
Balance, shares at Sep. 30, 2021		135,885,104				500,000
Balance, amount at Sep. 30, 2021	4,647,671	$ 13,589				$ 50	4,457,500	50,009,591		(49,833,059)
Balance, shares at Mar. 31, 2021		127,528,507				500,000
Balance, amount at Mar. 31, 2021	1,628,528	$ 12,753	0	$ 0	$ 0	$ 50	303,500	44,026,683	0	(42,714,458)
Common stock issued for services, shares		1,114,351
Common stock issued for services, amount	776,500	$ 111					(16,000)	792,389
Net loss	(3,826,924)									(3,826,924)
Stock based compensation - stock options	91,526	$ 0						91,526
Loss on extinguishment of debt	1,535,264							1,535,264
Common stock issued for cash, shares		1,234,113
Common stock issued for cash, amount	249,999	$ 123					(152,500)	402,376
Convertible note #5 and accrued interest converted to common stock, shares		2,647,464
Convertible note #5 and accrued interest converted to common stock, amount	582,707	$ 265						582,442
S-1 agreement subscription receivable, shares		500,000
S-1 agreement subscription receivable, amount	0	$ 50						332,450	(332,500)
Balance, shares at Jun. 30, 2021		133,024,435				500,000
Balance, amount at Jun. 30, 2021	1,037,600	$ 13,302	$ 0			$ 50	135,000	47,763,130	(332,500)	(46,541,382)
Common stock to be issued for Note receivable and True-up adjustment	4,322,500						4,322,500
Common stock issued for services, shares		1,415,554
Common stock issued for services, amount	1,111,900	$ 142						1,111,758
Net loss	(3,291,677)									(3,291,677)
Stock based compensation - stock options	761,810							761,810
Common stock issued for cash, shares		1,445,115
Common stock issued for cash, amount	476,726	$ 145						476,581
Subscription receivable share price adjustment								(103,688)	103,688
Subscription price receivable	228,812								$ 228,812
Balance, shares at Sep. 30, 2021		135,885,104				500,000
Balance, amount at Sep. 30, 2021	$ 4,647,671	$ 13,589				$ 50	$ 4,457,500	$ 50,009,591		$ (49,833,059)

Unaudited Condensed Consolida_3

Unaudited Condensed Consolidated Statement of Cash Flows (Unaudited) - USD ($)	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (7,983,134)	$ (4,013,324)
Less: (Loss) gain from discontinued operations	(4,633)	29,144
Loss from continuing operations	(7,978,501)	(4,042,468)
Adjustments to reconcile net loss to cash provided by (used in) operating activities:
Depreciation	20,119	10,497
Stock based compensation	953,076	779,029
Amortization of prepaid insurance/expense	296,542	146,583
Amortization of debt discount	220,578	63,745
Common stock issued for services	1,904,400
Amortization(impairment) of Intangible Assets	1,333,954
Loss on extinguishment of debt	1,535,264	923,604
Unrealized (gain) loss on marketable securities	0	104,705
Realized (gain) loss on marketable securities	0	109,040
Changes in operating assets & liabilities:
Increase in interest receivable	(770)	(419)
Increase in prepaid expenses	(182,161)	(94,779)
Increase (decrease) in inventory	(20,127)	0
Increase (decrease) in security deposit		(255)
Increase in accounts payable and accrued expenses	228,426	234,364
Net cash provided by (used in) operating activities from continuing operations	(1,689,200)	(1,766,355)
Net cash provided by (used in) operating activities from discontinued operations	(4,633)	(834,429)
Net cash provided by (used in) operating activities	(1,693,833)	(2,600,784)
CASH FLOW FROM INVESTING ACTIVITIES:
Cash acquired in acquisition	0	79,814
Acquisition of patents	(10,000)
Increase (decrease) in property and equipment	(20,022)	(86,169)
Net cash provided by (used in) investing activities from continuing operations	(30,022)	(6,355)
Net cash provided by (used in) investing activities from discontinued operations	0	0
Net cash provided by (used in) investing activities	(30,022)	(6,355)
CASH FLOW FROM FINANCING ACTIVITIES:
Common stock issued under registration statement on Form S-3		1,510,500
Common stock issued under SPA	1,542,040	1,798,630
Borrowed from First Insurance Funding	40,511	8,618
Proceeds from common stock to be issued per stock purchase agreement	52,500
Repayment of Promissory note	(30,000)	0
Net cash provided by (used in) continuing financing activities	1,605,051	3,317,748
Net cash provided by (used in) discontinued financing activities	0	(65,000)
Net cash provided by (used in) financing activities	1,605,051	3,252,748
Net (decrease) increase in cash and cash equivalents	(118,804)	645,609
Cash and cash equivalents at beginning of period	457,181	511,630
Cash and cash equivalents at end of period	338,377	1,157,239
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION
Interest	0	0
Income taxes - net of tax refund	0	0
NON-CASH INVESTING AND FINANCING ACTIVITIES
Common stock issued against common stock to be issued	66,974	50,000
Account receivable against conversion of debt and interest		75,074
Common stock issued for services recorded as prepaid expense	0	302,000
Common stock issued for severance	225,000	450,000
Shares issued for acquisition of Sapphire Biotechnology	0	7,506,000
Deferred tax liability accounted for as a result of Sapphire Biotech Acquisition	0	1,845,000
Assets acquired and liability assumed for as a result of Sapphire Biotech Acquisition	0	525,365
BCF related to discount on conversion	0	190,000
Common stock issued for note receivable	0	135,000
Adoption of lease obligation and ROU asset	0	164,910
Common stock retired	0	1,857
Subscription price adjustment	0	609,835
Convertible note converted to common stock	0	51,414
Assets acquired as a result of Sapphire Biotech Acquisition	0	33,319
Acquisition of patents against Notes payable and accounts payable	240,000	0
Common stock to be issued for acquisition	$ 4,270,000	$ 0

ORGANIZATION

ORGANIZATION	9 Months Ended
	Sep. 30, 2021
ORGANIZATION
NOTE 1: ORGANIZATION	NOTE 1: ORGANIZATION Axim Biotechnologies, Ind., (the “Company”) was originally incorporated in Nevada on November 18, 2010, as Axim International Inc. On July 24, 2014, the Company changed its name to AXIM Biotechnologies, Inc. to better reflect its business operations. The Company’s principal executive office is located at 6181 Cornerstone Court E Suite 114, San Diego, CA 92121. On August 7, 2014, the Company formed a wholly owned Nevada subsidiary named Axim Holdings, Inc. This subsidiary will be used to help facilitate the anticipated activities planned by the Company. On May 11, 2015 the Company acquired a 100% interest in Can Chew License Company a Nevada incorporated licensing Company, through the exchange of 5,826,706 shares of its common stock. On March 17, 2020, the Company acquired Sapphire Biotech, Inc., (“Sapphire’) which is research and Development Company that has a mission to improve global cancer care through the development of proprietary therapeutics for inhibiting cancer growth and metastasis. Sapphire is also developing a line of novel diagnostics for early cancer detection, response to treatment, and recurrence monitoring. Additionally, with the onset of the COVID-19 pandemic, the Company decided to begin creating COVID-19 rapid diagnostic tools, including multiple first-in-class COVID-19 neutralizing antibody tests and other innovations. Sapphire’s operations are located in the Greater San Diego Area. Company Developments – Divesture of Cannabis Related Assets On May 6, 2020 (the “Effective Date”), AXIM Biotechnologies, Inc., a Nevada corporation (the “Company”), entered into an Agreement (the “Separation Agreement”) by and among the Company, CanChew License Company (“CanCo”), CanChew Biotechnologies, LLC (“CanChew”), Medical Marijuana, Inc., Dr. George A. Anastassov (“Dr. Anastassov”), Dr. Philip A. Van Damme (“Dr. Van Damme”), Lekhram Changoer (“Mr. Changoer”), Sanammad Foundation, Netherlands and Sanammad Foundation, US (collectively, the “Sanammad Parties”), pursuant to which, among other matters as described herein, Drs. Anastassov and Van Damme and Mr. Changoer resigned as members of the Company’s Board of Directors. Pursuant to the Separation Agreement, the Company transferred and assigned to an entity designated by Dr. Anastassov all of the Company’s cannabis-related intellectual property other than the inventions and discoveries described in that certain cannabis-related patent application filed by the Company’s wholly-owned subsidiary, Sapphire Biotech, Inc. (water-soluble cannabinoid molecules). The Company also transferred 100% of its interest in CanCo and CanChew to an entity designated by Dr. Anastassov. In consideration for the transfers set forth above, any and all indebtedness owed by the Company to CanChew, totaling approximately $2.61 million, was satisfied and paid in its entirety. In addition, in consideration for the payment by the Company of $65,000, the Company purchased 100% of the issued and outstanding shares of Series B Preferred Stock held by the Sanammad Parties. Such shares shall be retired to treasury of the Company. The Sanammad Parties also agreed to forfeit and assign back to treasury, for no consideration, a total of 18,570,356 shares of the Company’s common stock.

ACQUISITION OF SAPPHIRE BIOTECH

ACQUISITION OF SAPPHIRE BIOTECH, INC.	9 Months Ended
	Sep. 30, 2021
ACQUISITION OF SAPPHIRE BIOTECH, INC.
NOTE 2: ACQUISITION OF SAPPHIRE BIOTECH, INC.	NOTE 2: ACQUISITION OF SAPPHIRE BIOTECH, INC. On March 17, 2020, the Company entered into a Share Exchange Agreement (“Agreement”) with Sapphire Biotech, Inc., a Delaware corporation (“Sapphire”) and all the Sapphire stockholders (collectively, the “Sapphire Stockholders”). Following the closing of the transaction, Sapphire will become a wholly owned subsidiary of AXIM. Under the terms of the Agreement, the Company: (i) acquired 100% of Sapphire’s outstanding capital (consisting of 100,000,000 shares of common stock and zero (0) shares of Preferred Stock); and (ii) assume all of the outstanding debt of Sapphire. The outstanding debt includes two (2) convertible notes in the principal amounts of $310,000 and $190,000. Pursuant to the terms of the Share Exchange Agreement, the Company acquired 100% of the issued and outstanding shares of Sapphire by means of a share exchange with the Sapphire Stockholders in exchange for 54,000,000 newly issued shares of the common stock of AXIM (the “Share Exchange”). As a result of the Share Exchange, Sapphire became a 100% owned subsidiary of AXIM, which on a going forward basis will result in consolidated financial reporting by AXIM to include the results of Sapphire. The closing of the Share Exchange occurred concurrently with entry into the Share Exchange Agreement (the “Closing”). In March 2020, the Company acquired SAPPHIRE BIOTECH, Inc., a biotechnology company focusing on improving cancer care through the development of proprietary therapeutics for inhibiting cancer growth and metastasis. The Company issued 54,000,000 shares of common stock with a total fair value of $7,506,000 and assumed net liabilities of $412,233 (resulting in a total acquisition cost of $7,918,233), in exchange for all outstanding shares of SAPPHIRE BIOTECH, Inc. The Company accounted for the acquisition using the acquisition method of accounting for business combinations. On the acquisition date, the Company performed a preliminary allocation of the purchase price to include the tangible assets acquired and the liabilities assumed with the remainder of the purchase price allocated to patents pending approval, in-process research and development (IPR&D) and goodwill. The Company incurred $6,000 of acquisition-related costs, which will be recorded as expense after the evaluation work been completed. In addition, the Company recorded an estimated deferred tax liability on the assets acquired, except for goodwill for which deferred taxes are not applicable. The Company completed the valuation of the intangible assets acquired in the SAPPHIRE BIOTECH, Inc. transaction by September 2020. Pursuant to the valuation, the Company determined that the patents continue to be expanded and chose to subsume the patents within the IPR&D balance. In management’s judgment, the amount assigned to IPR&D represents the amount the Company would reasonably expect to pay an unrelated party for each project included in the technology. Based on the final valuation, the remaining excess purchase price has been allocated to goodwill. The aggregate purchase price of $7,918,233consisted of common stock valued at $7,506,000 and the net liabilities assumed of $412,233. The value of the $7,506,000 of common shares issued was determined based on the closing price of the Company’s common shares at the acquisition date. The following table summarizes the consideration paid for SAPPHIRE BIOTECH and the estimated amounts of the assets acquired and liabilities assumed recognized at the acquisition date. Consideration: Cash and cash equivalents $ 79,814 Property and equipment, net 20,533 In process Research & Development (IPRD) 7,800,000 Goodwill 2,458,233 Security deposit 12,785 Total asset acquired $ 10,371,365 Accrued expenses and other current liabilities $ 5,767 Deferred taxes liability 2,340,000 Notes Payable including convertible and discount on conversion 519,598 Total liabilities assumed $ 2,865,365 Net assets acquired $ 7,506,000 The fair value of acquired IPR&D was determined using the income approach, based on the likelihood of success of products reaching final development and commercialization. The fair value of acquired IPR&D was capitalized as of the Closing Date and is subsequently accounted for as an indefinite-lived intangible asset until completion or abandonment of the associated research and development efforts. Accordingly, during the development period after the Closing Date, this asset will not be amortized over a period of 36 months. The acquired in process Research and development as it relates to rapid COVID testing has reached the commercialization stage and is awaiting FDA EUA. The $2,458,233 of goodwill is not expected to be deductible for tax purposes. The effective settlement of receivable/payable between the Company and Sapphire deemed to be not material, which was recorded as gain on intercompany transaction in P&L.

ACQUISITION OF INTELLECTUAL PRO

ACQUISITION OF INTELLECTUAL PROPERTY0F ADVANCED TEAR DIAGNOSTIC, LLC.	9 Months Ended
	Sep. 30, 2021
ACQUISITION OF INTELLECTUAL PROPERTY0F ADVANCED TEAR DIAGNOSTIC, LLC.
NOTE 3: ACQUISITION OF INTELLECTUAL PROPERTY0F ADVANCED TEAR DIAGNOSTIC, LLC.	NOTE 3: ACQUISITION OF INTELLECTUAL PROPERTY 0F ADVANCED TEAR DIAGNOSTIC, LLC. AXIM entered into two substantially contemporaneous transactions to acquire patents and 510(K) Licenses from Tear Diagnostics, LLC (the “Seller”) (collectively, the “Asset Acquisition”) for a total amount of $4,520,000. The first transaction occurred on July 29, 2021, in which AXIM purchased five patents (the “Patents”) from the Seller for $250,000 (which includes assuming and paying $30,000 of the Seller’s liabilities). The bulk of the purchase price ($210,000) was in a note that requires seven equal monthly payments of $30,000, which payment started on September 3, 2021. The second transaction occurred on July 26, 2021, in which AXIM purchased certain eye disease diagnostic technology, which consisted of a 510(K) license for Lactoferrin, a biomarker for dry eye disease and a 510(K) license for IgE, a biomarker for allergic ocular reaction (collectively, the “510(K) Licenses”). The purchase price for the 510(K) Licenses was $4,270,000, which price was paid by issuing to the Seller 7 million shares of AXIM restricted common stock. Together, the Patents and the 510(K) Licenses constitute the acquired technology asset (the “Technology Asset”), which for accounting purposes, are considered one unit of account. We are amortizing the Technology Asset ratably over the 11.54 average remaining life of the Patents. In accordance with FASB’s requirements for accounting for business combinations (FASB Accounting Standards Codification, Topic 805, Business Combinations

BASIS OF PRESENTATION

BASIS OF PRESENTATION	9 Months Ended
	Sep. 30, 2021
BASIS OF PRESENTATION
NOTE 4: BASIS OF PRESENTATION:	NOTE 4: BASIS OF PRESENTATION: The unaudited condensed consolidated financial statements of AXIM Biotechnologies, Inc. (formerly Axim International, Inc.) as of September 30, 2021, and for the three and nine months period ended September 30, 2021 and 2020 have been prepared in accordance with United States generally accepted accounting principles (“US GAAP”). The following (a) balance sheets as of September 30, 2021 (unaudited) and December 31, 2020, which have been derived from audited financial statements, and (b) the unaudited interim statements of operations and cash flows of AXIM Biotechnologies, Inc. (the “Company”) have been prepared in accordance with accounting principles generally accepted in the United States (“GAAP”) for interim financial information and the instructions to Form 10-Q and Rule 8-03 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included. Operating results for the three and nine months ended September 30, 2021 are not necessarily indicative of results that may be expected for the year ending December 31, 2021. These unaudited financial statements should be read in conjunction with the audited financial statements and notes thereto for the year ended December 31, 2020 included in the Company’s Annual Report on Form 10-K, filed with the Securities and Exchange Commission (“SEC”) on April 26, 2021. Principles of Consolidation The consolidated financial statements include the accounts of Axim Biotechnologies, Inc. and its wholly owned subsidiaries Axim Holdings, Inc., Marina Street LLC, Axim Biotechnologies (the Netherland Company) and Sapphire Biotech, Inc. The consolidated financial statements include the accounts of the Company and its wholly-owned subsidiaries. All significant inter-company balances and transactions have been eliminated upon consolidation.

GOING CONCERN

GOING CONCERN	9 Months Ended
	Sep. 30, 2021
GOING CONCERN
NOTE 5: GOING CONCERN	NOTE 5: GOING CONCERN The Company’s condensed consolidated financial statements have been presented assuming that the Company will continue as a going concern. The Company has incurred significant losses and negative cash flows from operations in all periods since inception and had an accumulated deficit as of September 30, 2021. The Company has historically financed its operations primarily through the sale of common stock, promissory notes and convertible notes. To date, none of the Company’s products related to continuing operations are still in the product development phase. Management expects operating losses to continue and increase for the foreseeable future, as the Company progresses into clinical development activities for its lead product candidates. The Company’s prospects are subject to risks, expenses and uncertainties frequently encountered by companies in the biotechnology industry. As shown in the condensed consolidated financial statements, the Company has deficit in working capital of $1,094,813 and has an accumulated deficit of $49,833,059 and has cash used in operating activities of continuing operations $1,689,200 and discontinued operations of $4,633. The Company intends to raise substantial additional capital through private placements of debt and equity securities, but there can be no assurance that these funds will be available on terms acceptable to the Company or will be sufficient to enable the Company to fully complete its development activities or sustain operations. If the Company is unable to raise sufficient additional funds, it will have to develop and implement a plan to further extend payables, reduce overhead, or scale back its current business plan until sufficient additional capital is raised to support further operations. There can be no assurance that such a plan will be successful. That will raise a doubt about the ability of the Company to continue as a going concern. The unaudited condensed consolidated financial statements do not include any adjustments related to the recoverability of assets and classification of liabilities that might be necessary should the Company be unable to continue in operation.

SIGNIFICANT ACCOUNTING POLICIES

SIGNIFICANT ACCOUNTING POLICIES	9 Months Ended
	Sep. 30, 2021
SIGNIFICANT ACCOUNTING POLICIES
NOTE 6: SIGNIFICANT ACCOUNTING POLICIES	NOTE 6: SIGNIFICANT ACCOUNTING POLICIES Use of estimates The preparation of the unaudited condensed consolidated financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements as well as the reported amounts of revenue and expenses during reporting periods. Actual results could differ from these estimates. Significant estimates are assumptions about collection of accounts receivable, intangible assets, useful life of intangible assets, determination of the discount rate for operating leases and assumptions used in Black-Scholes-Merton, or BSM, valuation methods, such as expected volatility, risk-free interest rate and expected dividend rate. Risks and uncertainties The Company operates in a dynamic and highly competitive industry and is subject to risks and uncertainties common to early-stage companies in the biotechnology industry, including, but not limited to, development by competitors of new technological innovations, protection of proprietary technology, dependence on key personnel, contract manufacturer and contract research organizations, compliance with government regulations and the need to obtain additional financing to fund operations. Product candidates currently under development will require significant additional research and development efforts, including extensive preclinical studies and clinical trials and regulatory approval, prior to commercialization. These efforts require significant amounts of additional capital, adequate personnel infrastructure and extensive compliance and reporting. The Company believes that changes in any of the following areas could have a material adverse effect on the Company’s future financial position, results of operations, or cash flows; ability to obtain future financing; advances and trends in new technologies and industry standards; results of clinical trials; regulatory approval and market acceptance of the Company’s products; development of sales channels; certain strategic relationships; litigation or claims against the Company based on intellectual property, patent, product, regulatory, or other factors; and the Company’s ability to attract and retain employees necessary to support its growth. Products developed by the Company require approvals from the U.S. Food and Drug Administration (“FDA”) or other international regulatory agencies prior to commercial sales. There can be no assurance that the Company’s research and development will be successfully completed, that adequate protection for the Company’s intellectual property will be obtained or maintained, that the products will receive the necessary approvals, or that any approved products will be commercially viable. If the Company was denied approval, approval was delayed or the Company was unable to maintain approval, it could have a materially adverse impact on the Company. Even if the Company’s product development efforts are successful, it is uncertain when, if ever, the Company will generate revenue from product sales. The Company operates in an environment of rapid change in technology and substantial competition from other pharmaceutical and biotechnology companies. In addition, the Company is dependent upon the services of its employees, consultants and other third parties. Beginning in late 2019, the outbreak of a novel strain of virus named SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), or coronavirus, which causes coronavirus disease 2019, or COVID-19, has evolved into a global pandemic. The extent of the impact of the coronavirus outbreak on the Company’s business will depend on certain developments, including the duration and spread of the outbreak and the extent and severity of the impact on the Company’s clinical trial activities, research activities and suppliers, all of which are uncertain and cannot be predicted. At this point, the extent to which the coronavirus outbreak may materially impact the Company’s financial condition, liquidity or results of operations is uncertain. The Company has expended and will continue to expend substantial funds to complete the research, development and clinical testing of product candidates. The Company also will be required to expend additional funds to establish commercial-scale manufacturing arrangements and to provide for the marketing and distribution of products that receive regulatory approval. The Company may require additional funds to commercialize its products. The Company is unable to entirely fund these efforts with its current financial resources. If adequate funds are unavailable on a timely basis from operations or additional sources of financing, the Company may have to delay, reduce the scope of or eliminate one or more of its research or development programs which would materially and adversely affect its business, financial condition and operations. There have been no material changes in the accounting policies from those disclosed in the financial statements and the related notes included in the Form 10-K. Cash equivalents The Company considers all highly liquid investments with original maturities of three months or less at the time of purchase to be cash equivalents. As of September 30, 2021 and December 31, 2020, the Company had no cash equivalents. Cash and cash equivalents are maintained at financial institutions and, at times, balances may exceed federally insured limits. The Company had no uninsured balances at September 30, 2021 and December 31, 2020. The Company has never experienced any losses related to these balances. Accounts Receivable It is the Company’s policy to review accounts receivable at least on monthly basis for conductibility and follow up with customers accordingly. COVID19 has slowed collection as our customers are in a mandated pause. The Company have geographic concentration of customers for the three months ending September 30, 2021 and 2020. There were no accounts receivable as of September 30, 2021’ Concentrations At December 31, 2020, one customer accounted for 100% of accounts receivable. There were no accounts receivable as of September 30, 2021. Inventory Inventory consists of raw materials owned by the Company and are stated at the lower of cost or market. As of September 30, 2021 and December 31, 2020, the Company had $20,127 and $-0-; respectively. Property and equipment Property and equipment are carried at cost less accumulated depreciation. Depreciation is computed using straight-line method over the estimated useful life. New assets and expenditures that extend the useful life of property or equipment are capitalized and depreciated. Expenditures for ordinary repairs and maintenance are charged to operations as incurred. The Company’s property and equipment relating to continuing operations consisted of the following on September 30, 2021 and December 31, 2020, respectively, and none related to discontinued operations. September 30, December 31, 2021 2020 Equipment $ 154,809 $ 134,788 Less: accumulated depreciation $ 50,812 $ 30,694 $ 103,997 $ 104,094 For the nine months ended September 30, 2021 and 2020, the Company recognized depreciation expense of $20,119 and $10,497 respectively. For the three months ended September 30, 2021 and 2020, the Company recognized depreciation expense of $6,935 and $5,372, respectively. In-Process Research and Development (IPR&D) The fair value of IPR&D acquired through a business combination is capitalized as an indefinite-lived intangible asset until the completion or abandonment of the related research and development activities. When the related research and development is completed, the asset will be assigned a useful life and amortized. The fair value of an IPR&D intangible asset is determined using an income approach. This approach starts with a forecast of the net cash flows expected to be generated by the asset over its estimated useful life. The net cash flows reflect the asset’s stage of completion, the probability of technical success, the projected costs to complete, expected market competition, and an assessment of the asset’s life-cycle. The net cash flows are then adjusted to present value by applying an appropriate discount rate that reflects the risk factors associated with the cash flow streams. The product development related to the IPR&D acquired reached completion in April 2021. Goodwill Goodwill represents the excess of the purchase price of acquired businesses over the estimated fair value of the identifiable net assets acquired. Goodwill is not amortized but is tested for impairment at least annually at the reporting unit level or more frequently if events or changes in circumstances indicate that the asset might be impaired. Goodwill is tested for impairment annually or more frequently if events or changes in circumstances between annual tests indicate that the asset may be impaired. Impairment loss is recognized based on a comparison of the fair value of the asset to it carrying value, without consideration of any recoverability. Intangible Assets As required by generally accepted accounting principles, trademarks and patents are amortized if they have a definite life, the amortization is estimated in straight line through three years starting in April 2021. As a result of the acquisition of asset of Advanced Tear Diagnostic, LLC, we recognize patents and licenses, which are amortized in straight line over their remaining useful lives. The Company’s intangible assets relating to continuing operations and discontinued operations consisted of the following on September 30, 2021 and December 31, 2020, respectively. September 30, December 31, 2021 2020 Goodwill $ 2,458,233 $ 2,458,233 Intellectual Property (IPRD) 7,800,000 7,800,000 Patents 250,000 - Licenses 4,270,000 - 14,778,233 10,258,233 Less: accumulated amortization 1,333,954 - $ 13,444,279 $ 10,258,233 Estimated aggregate amortization expense for each of the three succeeding years ending December 31 is as follows: 2021 2022 2023 2024 Amortization expense $ 2,088,000 $ 2,990,000 $ 2,990,000 $ 1,040,000 Revenue Recognition The Company follows the guidance contained in Topic 606 (FASB ASC 606). The core principle of Topic 606 (FASB ASC 606) is that an entity should recognize revenue to depict the transfer of goods of services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. The revenue recognition guidance contained in Topic 606, to follow the five-step revenue recognition model along with other guidance impacted by this standard: (1) identify the contract with the customer; (2) identify the performance obligations in the contract; (3) determine the transportation price; (4) allocate the transportation price; (5) recognize revenue when or as the entity satisfies a performance obligation. All revenue was from operations that were divested. Revenues are recognized when title for goods is transferred; non-refundable fees and proceeds from irrevocable agreements recognized when inflows or other enhancements of assets of the Company are received. Revenues from continuing operations recognized for three and nine months ended September 30, 2021 and 2020 amounted to $8,127, $55,651, $-0- and $-0-, respectively. Revenues from discontinued operations recognized for three and nine months ended September 30, 2021 and 2020 amounted to $-0-, $-0-, and $-0-, $7,990, respectively. Collaboration Revenue Revenue recognition for collaboration agreements will require significant judgment. The Company’s assessments and estimates are based on contractual terms, historical experience and general industry practice. Revisions in these values or estimations have the effect of increasing or decreasing collaboration revenue in the period of revision. On August 21, 2020, the Company entered into a Distribution, License and Supply Agreement (“License Agreement”) with Empowered Diagnostics, LLC ("Empowered Diagnostics”"). The License Agreement has a term of xx years and provides Empowered Diagnostics with a right to commercialize The company’s products worldwide with the exception of Mexico. Under the License Agreement, the company is responsible for applying for and obtaining necessary regulatory approvals in the US and EU, as well as marketing, sales and distribution of the products. Empowered Diagnostics will pay a transfer price for all licensed products, and upon achievement of certain regulatory and sales milestones, the Company may receive payments from Empowered Diagnostics equal to 8% of the monthly gross revenue. Agreement continues until terminated by mutual consent or uncorrected breach. Grant Income In 2021 the Company has received government grants to drive its research and development efforts. Through these government grants, the government has provided funding for the Company to perform research and development activities which will assist in developing its products. The Company believes the government entities funding these grants are interested in the Company advancing its underlying technologies through research activities and not providing incentives for hiring employees or building facilities that would suggest that the grant monies are not for specific research activities. In determining how to classify the monies received under government grants, the Company acknowledges that there is no specific guidance under US GAAP and that the FASB and AICPA have often drawn upon the guidance in IAS 20 for classification. In considering the alternatives provided by IAS 20 for the presentation of these grants in the Company’s financial statements, the Company believes that recognizing the government grant proceeds as a component of other revenue is a better reflection of the economics of the arrangements as the Company earns the funding through the performance of research and development which is not one of the Company’s primary business activities or central to its operations. The Company believes that presenting research and development funding from government grants, as other revenue provides consistency in our financial reporting. The Company also believes that this presentation clearly presents to users of its financial statements in one line the Company’s sources of funding from these grants. The Company notes that there are no contingencies associated with the receipt of or ability to retain the funds under the grant, other than undertaking and performing the related research and development activities. The Company recognizes funds received from contractual research and development services and from government grants as other revenue. These contracts and grants are not considered an ongoing major and central operation of the Company’s business. Our Income from Grants from Government for the three and nine months ended September 30, 2021 and 2020, was $59,986, $279,981 and $25,899, $25,899 respectively. Cost of Sales Cost of sales includes the purchase cost of products sold and all costs associated with getting the products to the customers including buying and transportation costs. Cost of sales all related to discontinued operations. Shipping Costs Shipping and handling costs billed to customers are recorded in sales. Shipping costs incurred by the company are recorded in general and administrative expenses. Shipping costs all related to discontinued operations. Fair Value Measurements The Company applies the guidance that is codified under ASC 820-10 related to assets and liabilities recognized or disclosed in the financial statements at fair value on a recurring basis. ASC 820-10 defines fair value, establishes a framework for measuring fair value and expands disclosures about fair value measurements. Convertible Instruments The Company evaluates and accounts for conversion options embedded in its convertible instruments in accordance with professional standards for “Accounting for Derivative Instruments and Hedging Activities.” Professional standards generally provide three criteria that, if met, require companies to bifurcate conversion options from their host instruments and account for them as free-standing derivative financial instruments. These three criteria include circumstances in which (a) the economic characteristics and risks of the embedded derivative instruments are not clearly and closely related to the economic characteristics and risks of the host contract, (b) the hybrid instrument that embodies both the embedded derivative instrument and the host contract is not re-measured at fair value under otherwise applicable generally accepted accounting principles with changes in fair value reported in earnings as they occur and (c) a separate instrument with the same terms as the embedded derivative instrument would be considered a derivative instrument. Professional standards also provide an exception to this rule when the host instrument is deemed to be conventional as defined under professional standards as “The Meaning of “Conventional Convertible Debt Instrument.” The Company accounts for convertible instruments (when it has determined that the embedded conversion options should not be bifurcated from their host instruments) in accordance with professional standards when “Accounting for Convertible Securities with Beneficial Conversion Features,” as those professional standards pertain to “Certain Convertible Instruments.” Accordingly, the Company records, when necessary, discounts to convertible notes for the intrinsic value of conversion options embedded in debt instruments based upon the differences between the fair value of the underlying common stock at the commitment date of the note transaction and the effective conversion price embedded in the note. Debt discounts under these arrangements are amortized over the term of the related debt to their earliest date of redemption. The Company also records when necessary deemed dividends for the intrinsic value of conversion options embedded in preferred shares based upon the differences between the fair value of the underlying common stock at the commitment date of the note transaction and the effective conversion price embedded in the note. ASC 815-40 provides that, among other things, generally, if an event is not within the entity’s control could or require net cash settlement, then the contract shall be classified as an asset or a liability. Income Taxes The Company follows Section 740-10, Income tax (“ASC 740-10”) Fair Value Measurements and Disclosures of the FASB Accounting Standards Codification, which requires recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been included in the financial statements or tax returns. Under this method, deferred tax assets and liabilities are based on the differences between the financial statement and tax bases of assets and liabilities using enacted tax rates in effect for the year in which the differences are expected to reverse. Deferred tax assets are reduced by a valuation allowance to the extent management concludes it is more likely than not that the assets will not be realized. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in the Statements of Operations in the period that includes the enactment date. The Company recognizes deferred tax assets to the extent that the Company believes that these assets are more likely than not to be realized. In making such a determination, the Company considers all available positive and negative evidence, including reversals of any existing taxable temporary differences, projected future taxable income, tax planning strategies, and the results of recent operations. If the Company determines that it would be able to realize a deferred tax asset in the future in excess of any recorded amount, the Company would make an adjustment to the deferred tax asset valuation allowance, which would reduce the provision for income taxes. The Company adopted section 740-10-25 of the FASB Accounting Standards Codification (“Section 740-10-25”). Section 740-10-25 addresses the determination of whether tax benefits claimed or expected to be claimed on a tax return should be recorded in the financial statements. Under Section 740-10-25, the Company may recognize the tax benefit from an uncertain tax position only if it is more likely than not that the tax position will be sustained on examination by the taxing authorities, based on the technical merits of the position. The tax benefits recognized in the financial statements from such a position should be measured based on the largest benefit that has a greater than fifty percent (50%) likelihood of being realized upon ultimate settlement. Section 740-10-25 also provides guidance on de-recognition, classification, interest and penalties on income taxes, accounting in interim periods and requires increased disclosures. The Company had no liabilities for unrecognized income tax benefits according to the provisions of Section 740-10-25. Concentrations of Credit Risk Financial instruments and related items, which potentially subject the Company to concentrations of credit risk, consist primarily of cash and cash equivalents. The Company places its cash and temporary cash investments with credit quality institutions. At times, such amounts may be in excess of the FDIC insurance limit. Net Loss per Common Share Net loss per common share is computed pursuant to section 260-10-45 Earnings Per Share (“ASC 260-10”) of the FASB Accounting Standards Codification. Basic net loss per share is computed by dividing net loss by the weighted average number of shares of common stock outstanding during the period. Diluted net loss per share is computed by dividing net loss by the weighted average number of shares of common stock outstanding and the member potentially outstanding during each period. In periods when a net loss is experienced, only basic net loss per share is calculated because to do otherwise would be anti-dilutive. There were 30,530,216 common share equivalents at September 30, 2021 and 32,556,727 common shares at December 31, 2020. For the nine months ended September 30, 2021 and 2020 these potential shares were excluded from the shares used to calculate diluted earnings per share as their inclusion would reduce net loss per share. Stock Based Compensation All stock-based payments to employees and to nonemployee directors for their services as directors, including any grants of restricted stock and stock options, are measured at fair value on the grant date and recognized in the statements of operations as compensation or other expense over the relevant service period. Stock-based payments to nonemployees are recognized as an expense over the period of performance. Such payments are measured at fair value at the earlier of the date a performance commitment is reached, or the date performance is completed. In addition, for awards that vest immediately and are non-forfeitable the measurement date is the date the award is issued. The Company accounts for stock options issued to non-employees based on the estimated fair value of the awards using the Black-Scholes option pricing model in accordance with ASC 505-50, Equity-Based Payment to Non-employees Research and Development The Company accounts for research and development costs in accordance with the Accounting Standards Codification subtopic 730-10, Research and Development (“ASC 730-10”). Under ASC 730-10, all research and development costs must be charged to expense as incurred. Accordingly, internal research and development costs are expensed as incurred. Third-party research and development costs are expensed when the contracted work has been performed or as milestone results have been achieved. Company-sponsored research and development costs related to both present and future products are expensed in the period incurred. For the three and nine months ended September 30, 2021 and 2020 the Company incurred research and development expenses of $67,263, $216,282 and $109,139, $235,431 from continuing operations, respectively. For the three and nine months ended September 30, 2021 and 2020 the Company incurred research and development expenses of $-0-, $-0- and $(400,417), $426,665 from discontinued operations, respectively. The Company has entered into various agreements with CROs. The Company’s research and development accruals are estimated based on the level of services performed, progress of the studies, including the phase or completion of events, and contracted costs. The estimated costs of research and development provided, but not yet invoiced, are included in accrued liabilities on the balance sheet. If the actual timing of the performance of services or the level of effort varies from the original estimates, the Company will adjust the accrual accordingly. Payments made to CROs under these arrangements in advance of the performance of the related services are recorded as prepaid expenses and other current assets until the services are rendered. Recently Issued Accounting Standards Accounting Standards Implemented Since December 31, 2020 ASC Update 2021-04 Earnings Per Share (Topic 260), Debt—Modifications and Extinguishments (Subtopic 470-50), Compensation—Stock Compensation (Topic 718), and Derivatives and Hedging—Contracts in Entity’s Own Equity (Subtopic 815-40): Issuer’s Accounting for Certain Modifications or Exchanges of Freestanding Equity-Classified Written Call Options (a consensus of the FASB Emerging Issues Task Force) The amendments in this Update affect all entities that issue freestanding written call options that are classified in equity. Specifically, the amendments affect those entities when a freestanding equity-classified written call option is modified or exchanged and remains equity classified after the modification or exchange. The amendments that relate to the recognition and measurement of EPS for certain modifications or exchanges of freestanding equity-classified written call options affect entities that present EPS in accordance with the guidance in Topic 260, Earnings Per Share. The amendments in this Update do not apply to modifications or exchanges of financial instruments that are within the scope of another Topic. That is, accounting for those instruments continues to be subject to the requirements in other Topics. The amendments in this Update do not affect a holder’s accounting for freestanding call options. ASC Update No. 2020-10 In October 2020, the FASB issued ASC Update No. 2020-10, Codification Improvements. Update No. 2020-10 amends a wide variety of Topics in the Codification in order to improve the consistency of the Codification and the application thereof, while leaving Generally Accepted Accounting Principles unchanged. ASC Update No. 2020-06 In August 2020, the FASB issued ASC Update No. 2020-06, Debt – Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging – Contracts in Entity’s Own Equity (Subtopic 815-40): Accounting for Convertible Instruments and Contracts in an Entity’s Own Equity. The amendments in Update No. 2020-06 simplify the complexity associated with applying U.S. GAAP for certain financial instruments with characteristics of liabilities and equity. More specifically, the amendments focus on the guidance for convertible instruments and derivative scope exception for contracts in an entity’s own equity Other recent accounting pronouncements issued by the FASB and the SEC did not or are not believed by management to have a material impact on the Company’s present or future consolidated financial statements.

PREPAID EXPENSES

PREPAID EXPENSES	9 Months Ended
	Sep. 30, 2021
PREPAID EXPENSES
NOTE 7: PREPAID EXPENSES	NOTE 7: PREPAID EXPENSES Prepaid expenses consist of the following as of September 30, 2021 and December 31, 2020: September 30, December 31, 2021 2020 Prepaid insurance $ 96,881 $ 45,983 Prepaid services 44,661 209,940 $ 141,542 $ 255,923 For the three and nine months ended September 30, 2021 and 2020, the Company recognized amortization of prepaid expense of $80,384, $296,542 and $78,504, $146,583, respectively.

PROMISSORY NOTE

PROMISSORY NOTE	9 Months Ended
	Sep. 30, 2021
PROMISSORY NOTE
NOTE 8: PROMISSORY NOTE	NOTE 8: PROMISSORY NOTE On August 8, 2014 the Company entered into a Promissory Note Agreement with CanChew Biotechnologies, LLC (CCB), a related party (the owners of CCB also own a majority of the outstanding shares of the Company), under which it borrowed $1,000,000 to fund working capital. The original loan was a demand note bearing interest at the rate of 7% per annum, which amount, along with principal, was payable upon demand. The demand note was amended effective January 1, 2015 to reduce the annual interest rate to 3%. All other terms and conditions shall remain in full force and effect. The Company is in discussions to have the demand note modified or exchanged for a longer term, fixed maturity note. On May 6, 2020 (the “Effective Date”), AXIM Biotechnologies, Inc., a Nevada corporation (the “Company”), entered into an Agreement (the “Separation Agreement”). Pursuant to the Separation Agreement, the Company transferred 100% of its interest in CanCo and CanChew to an entity designated by Dr. Anastassov. In consideration for the transfers set forth above, any and all indebtedness owed by the Company to CanChew, totaling approximately $2.61 million, was satisfied and paid in its entirety. For the three and nine months ended September 30, 2021 and 2020, the Company recognized interest expense of $0, $0 and $0, $0, respectively on this note all was related to continuing operations. On December 31, 2019, Sapphire Biotech, Inc. had entered into a Debt Exchange Agreement whereas the Company assumed three (3) loans totaling $128,375 of Debt owned by Sapphire Diagnostics, LLC which had an interest rate of 6% per annum. In the same Debt Exchange Agreement, the Company assumed four (4) additional loans made to Sapphire in 2019, which had an interest rate of 6% per annum. All seven (7) loans totaling $310,000, plus the aggregate interest accrued thereon of $14,218 making the face value of the new note $324,218. As of September 30, 2021 and December 31, 2020, the principal and accrued interest balances were $358,315 and $343,725, respectively. The Company owes $5,000 to the chairman of the board of the Company for a working capital advance of $5,000 made in May of 2014, all was related to discontinued operations. Under an agreement Mr. Changoer received on March 20, 2018 the Company issued 50,000 restrictive shares of its common stock and recorded $235,000of compensation expenses in the accompanying consolidated financial statements to account for the issuance of the incentive shares. As of September 30, 2021 and December 31, 2020, the total outstanding balance was $20,000 and $60,000 respectively for consulting fees to Mr. Changoer included in accounts payable. On September 25, 2018, the Company amended Independent Director Compensation agreement. Under the agreement in lieu of the share compensation due to independent director of the Company for his annual service ending May 23, Dr. Philip A. Van Damme shall receive cash compensation of $20,000. Started from August 1, 2019 the company has been paying monthly clinical trial fee of $5,000. As of September 30, 2021 and December 31, 2020, the total outstanding balance was $-0- and $25,000, respectively included in accounts payable. Effective January 1, 2019 the company entered into a thirty-months consulting agreement with the chairman of the board which pays a monthly consulting fee of $20,000. The company has also been paying a monthly bonus fee of 15,000; this additional fee is on a month-to-month basis at the discretion of management. As of September 30, 2021 and December 31, 2020, the total outstanding balance was $40,000 and $225,000 respectively for consulting fees included in accounts payable. On May 6, 2020 (the “Effective Date”), AXIM Biotechnologies, Inc., a Nevada corporation (the “Company”), entered into an Agreement (the “Separation Agreement”) by and among the Company, CanChew License Company (“CanCo”), CanChew Biotechnologies, LLC (“CanChew”), Medical Marijuana, Inc., Dr. George A. Anastassov (“Dr. Anastassov”), Dr. Philip A. Van Damme (“Dr. Van Damme”), Lekhram Changoer (“Mr. Changoer”), Sanammad Foundation, Netherlands and Sanammad Foundation, US (collectively, the “Sanammad Parties”), pursuant to which, among other matters as described herein, Drs. Anastassov and Van Damme and Mr. Changoer resigned as members of the Company’s Board of Directors. Pursuant to the Separation Agreement, the Company transferred and assigned to an entity designated by Dr. Anastassov all of the Company’s cannabis-related intellectual property other than the inventions and discoveries described in that certain cannabis-related patent application filed by the Company’s wholly-owned subsidiary, Sapphire Biotech, Inc. (water-soluble cannabinoid molecules). The Company also transferred 100% of its interest in CanCo and CanChew to an entity designated by Dr. Anastassov. In consideration for the transfers set forth above, any and all indebtedness owed by the Company to CanChew, totaling approximately $2.61 million, was satisfied and paid in its entirety. In addition, in consideration for the payment by the Company of $65,000, the Company purchased 100% of the issued and outstanding 500,000 shares of Series B Preferred Stock held by the Sanammad Parties. Such shares shall be retired to treasury of the Company. The Sanammad Parties also agreed to forfeit and assign back to treasury, for no consideration, a total of 18,570,356 shares of the Company’s common stock. In addition, each of Drs. Anastassov and Van Damme and Mr. Changoer have agreed to subject the shares of the Company’s common stock held by each of them to lock-up and leak-out restrictions, as follows: they shall not sell shares for a period of 12 months following the Effective Date and, thereafter, subject to a daily volume limitation of 5%, on an aggregate basis among them. Further, the Company terminated the Consulting Agreement of Dr. Anastassov and the Employment Agreements for each of Dr. Van Damme and Mr. Changoer. In connection with the termination of Dr. Anastassov’s Consulting Agreement, the Company agreed to pay severance in the amount of $35,000 for March 2020 and $20,000 per month thereafter through July 2021 (the termination date contemplated by the Consulting Agreement). Commencing for the April 2020, the Company may, in its sole discretion, pay the $20,000 severance obligation by the issuance of shares of the Company’s common stock registered pursuant to the Registration Statement on Form S-8 filed with the Commission on May 29, 2015 (“S-8 Shares”). If the gross cash proceeds from the sale of any S-8 Shares issued in lieu of cash severance is less than $20,000, as determined 20 days after issuance of such S-8 Shares, then the Company has agreed to issue additional shares that would serve to “true-up” the value of the shares to the $20,000 monthly severance obligation; provided, however, that if 30 days after the date the severance payment is due the gross proceeds from the sale of S-8 Shares is less than $20,000, the Company must pay the shortfall in cash. In addition, for each month that Dr. Anastassov is entitled to receive severance, he shall receive S-8 Shares in an amount equal to the lesser of (a) 150,000 S-8 Shares, or (b) S-8 Shares valued at $15,000 based upon the closing price of the Company’s common stock as of the due date of the severance payment obligation. In connection with the termination of the Employment Agreements of Dr. Van Damme and Mr. Changoer, Mr. Changoer’s severance payments shall be $20,000 per month for 12 months, commencing April 2020 (paid in arrears) and Dr. Van Damme’s severance payments shall be $5,000 per month for 12 months, similarly commencing April 2020 and paid in arrears. The Company has the right to pay each of Dr. Van Damme’s and Mr. Changoer’s monthly severance payments in S-8 shares in lieu of cash subject to the same terms and restrictions (including true-up terms) as set forth above for Dr. Anastassov. As of September 30, 2021, the accrued severance payment was $40,000 to Dr. Anastassov, $20,000 to Mr. Changoer included in accounts payable. The Company retains the right to prepay the severance obligations to Drs. Anastassov and Mr. Changoer, without penalty. No claims were alleged by the Company against any party, and no claims were alleged against the Company. However, in connection with the transactions described above, the parties entered into a general mutual release of all claims. On July 29, 2021, the Company recorded a $210,000 note payable in conjunction with the acquisition of patents from Advanced Tear Diagnostics LLC. The note balance as of September 30, 2021 is $180,000 with accrued interest of $125.

RELATED PARTY TRANSACTIONS

RELATED PARTY TRANSACTIONS	9 Months Ended
	Sep. 30, 2021
RELATED PARTY TRANSACTIONS
NOTE 9: RELATED PARTY TRANSACTIONS	NOTE 9: RELATED PARTY TRANSACTIONS Related Party The company has an employment agreement with Catalina Valencia CEO Saphire Biotechnologies, Inc.at a rate of $15,000 per month commencing March 17, 2020. The agreement can be terminated with 30 days’ notice by either party. The company has a consulting agreement with Glycodots LLC whereby it will provide the services of Dr. Sergei A. Svarovsky at a rate of $15,000 per month commencing March 17, 2020. The agreement can be terminated with 30 days’ notice by either party. Purchase of Promissory Note and Forbearance Agreement Effective May 4, 2020, the Company acquired from TL-66, a California limited liability company (“Seller”), a promissory note issued to Seller by Dr. Anastassov (“Maker”) dated December 1, 2017, with a face value of $350,000 and a remaining balance due of approximately $100,000 (the “Note”). The purchase price for the Note was $100,000 payable by the Company issuing Seller One Million (1,000,000) restricted shares of the Company’s Common Stock. Effective May 6, 2020, the Company and Maker entered into a Forbearance Agreement whereby the Company agreed to forbear from making any collection efforts on the Note for a period of 24 months so long as Maker has not breached the Separation Agreement. Following 24 months, if there has been no breach of the Separation Agreement by Maker, repayment of the Note, including all principal and unpaid interest, will be waived in full. As of May, 4, 2020 the carrying value of the note receivable was $102,567, the value of the common stock to be issued was $135,000, resulting in a loss of $32,433 accounted as loss on debt extinguishment related to discontinued operations. The balance of the Note Receivable as of September 30, 2021 and December 31, 2020 is $102,567 for both periods, plus interest accrued thereon of $1,445 and $675, respectively.

DUE TO FIRST INSURANCE FUNDING

DUE TO FIRST INSURANCE FUNDING	9 Months Ended
	Sep. 30, 2021
DUE TO FIRST INSURANCE FUNDING
NOTE 10: DUE TO FIRST INSURANCE FUNDING	NOTE 10: DUE TO FIRST INSURANCE FUNDING On June 25, 2020, the Company renewed its D&O insurance policy with total premiums, taxes and fees for $93,357. A cash down payment of $18,671 was paid on July 6, 2020. Under the terms of the insurance financing, payments of $8,456, which include interest at the rate of 4.6% per annum, are due each month for nine months commencing on July 25, 2020. On June 25, 2021, the Company renewed its D&O insurance policy with total premiums, taxes and fees for $98,888. A cash down payment of $24,273 was paid on July 7, 2021. Under the terms of the insurance financing, payments of $1,797, which include interest at the rate of 4.420% per annum, are due each month for nine months commencing on July 25, 2021. The total outstanding due to First Insurance Funding as of September 30, 2021 and December 31, 2020 is $65,880 and $25,369, respectively.

CONVERTIBLE NOTES PAYABLE

CONVERTIBLE NOTES PAYABLE	9 Months Ended
	Sep. 30, 2021
CONVERTIBLE NOTES PAYABLE
NOTE 11: CONVERTIBLE NOTES PAYABLE	NOTE 11: CONVERTIBLE NOTES PAYABLE The following table summarizes convertible note payable of related party as of September 30, 2021 and December 31, 2020: September 30, December 31, 2021 2020 Convertible note payable, due on November 1, 2026, interest at 3.5% p.a. $ 4,000,000 $ 4,000,000 Accrued interest 264,037 158,648 Convertible note payable, net $ 4,264,037 $ 4,158,648 The interest on this note is payable bi-annually every May 1 and November 1. On May 1, 2019 the Company paid accrued interest of $60,278. In 2020 the Company was authorized to apply the accounts receivable of $75,074 due from Kannaway towards its accrued interest. On May 1, 2020, the Company agreed to modify its existing convertible note with a principal balance of $4 million, 3.5% interest rate convertible note with the current holder of that note. There were two changes to the existing agreement – (a) the conversion price was reduced from the $1.50 conversion price in the original Note to $0.25 cents in the modified Note and (b) the term of the note was extended from the original maturity date of November 1, 2021, to November 1, 2026. The Company’s stock closed trading on the day of the modification at $0.13 per share. The amendment of this convertible Note was also evaluated under ASC Topic 470-50-40, ”Debt Modifications and Extinguishments.” Based on the guidance, the instruments were determined to be substantially different due to the change in the conversion price being substantial, and debt extinguishment accounting was applied. The fair value of the modified convertible note was not different than the carrying value of the original note as such no extinguishment loss was recorded, The Note prior to the amendment of approximately $4 million, and the fair value of the Note and embedded derivatives after the amendment of approximately $4 million. There were no unamortized debt issuance costs and the debt discount associated with the original 2018 Note. For the three and nine month ended September 30, 2021 and 2020, interest expenses was $35,000, $105,389 and $35,000, $105,389, respectively. As of September 30, 2021 and December 31, 2020, the balance of secured convertible note was $4,264,037 and $4,158,648which included $264,037 and $158,648 accrued interest, respectively. The following table summarizes convertible note payable as of September 30, 2021 and December 31, 2020: September 30, December 31, 2021 2020 Convertible note payable, due on October 1, 2029, interest at 3.5% p.a. $ 484,478 $ 484,478 Convertible note payable, due on October 1, 2029, interest at 3.5% p.a. 500,000 1,000,000 Convertible note payable, due on December 31, 2034, interest at 3% p.a. 190,000 190,000 Convertible note payable, due on July 21, 2032, interest at 3.5% p.a. 609,835 609,835 Accrued interest (The accrued interest and principal are both included in the captions titled “convertible note payable” in the balance sheet) 208,089 236,148 Total 1,992,402 2,520,461 Less: unamortized debt discount/finance premium costs (623,095 ) (843,673 ) Convertible note payable, net $ 1,369,307 $ 1,676,788 On September 16, 2016, we entered into a convertible note purchase agreement (the “Convertible Note Purchase Agreement” or “Agreement”) with a third-party investor. Under the terms of the Convertible Note Purchase Agreement the investor may acquire up to $5,000,000 of convertible notes from the Company. With various closings, under terms acceptable to the Company and the investor as of the time of each closing. Pursuant to the Agreement, on September 16, 2016 the investor provided the Company with $850,000 secured convertible note financing pursuant to four (4) Secured Convertible Promissory Notes (the “Notes”). Each of the Notes matures on October 1, 2029, and pay 3.5% compounded interest paid bi-annually. The Note are secured by the assets of the Company, may not be pre-paid without the consent of the holder, and are convertible at the option of the holder into shares of the Company common stock at a conversion price equal to $0.2201 per share. As of September 30, 2021 and December 31, 2020, the balance of secured convertible notes was $569,278 and $556,420, which included $84,800 and $71,942 accrued interest, respectively. On October 20, 2016 a third-party investor provided the Company with $1,000,000 secured convertible note financing pursuant to three (3) Secured Convertible Promissory Notes (the “Notes”). Each of the Notes mature on October 1, 2029 and pay 3.5% compounded interest paid bi-annually. The Notes are secured by the assets of the Company, may not be pre-paid without the consent of the holder, and are convertible at the option of the holder into shares of the Company’s common stock at a fixed conversion price equal of $0.2201 per share. The investor paid cash of $500,000 for one of the Notes and issued to the Company two (2) secured promissory notes of $250,000 each for two (2) Convertible Notes of $250,000 each. The two secured promissory notes issued by the investor (totaling $500,000) as payment for two (2) secured Notes totaling $500,000 mature on February 1, 2017 ($250,000) and March 1, 2017 ($250,000), bear interest at the rate of 1% per annum, are full recourse and additionally secured by 10,486,303 shares of Medical Marijuana, Inc. (Pink Sheets symbol: MJNA) and were valued at $858,828 based upon the closing price of MJNA on October 20, 2016. A debt discount was recorded related to beneficial conversion feature inn connection with this convertible note of $499,318, related to the beneficial conversion feature of the note to be amortized over the life of the note or until the note is converted or repaid. As of September 30, 2021 and December 31, 2020, this note has not been converted and the balance of secured convertible notes was $587,744 and $1,148,944, which included $87,744 and $148,944 accrued interest, respectively. On June 7, 2021 the Company converted $500,000 of the Convertible Note with TL-66-LLC along with the accrued interest of $82,707 into 2,647,464 shares of the Company’s common stock at $0.2201 per share which resulted in a loss on extinguishment of debt of $1,535,264. On December 31, 2019, Sapphire Biotech, Inc. entered into a Convertible Note Purchase Agreement whereas the Company issued a convertible note with a face value of $190,000 with a compounding interest rate of 3% per annum, the interest shall be payable annually beginning on December 31, 2020 until the maturity date of December 31, 2034, at which time all principal and interest accrued thereon shall be due and payable. The Convertible Note is secured by substantially all the Company’s tangible and intangible assets. In addition, the Convertible Note includes various non-financial covenants including the Company may not enter into any agreement, arrangement or understanding of any kind that would result in a transaction, or series of transactions, that would result in the sale of 50% or more of the Company’s capital stock without the prior approval of the holder. Upon issuance, the Convertible Note was convertible into shares of the Company’s common stock at $1.90 per share. At December 31, 2019, the Company determined that the Convertible Note contained a beneficial conversion feature for which a full discount was recorded on the Convertible Note. The fair market value of the Company’s common stock was based upon the estimated per share acquisition price per the pending acquisition of the Company. The discount of $190,000 will be amortized using the effective interest method and will be fully amortized by December 31, 2034. On March 17, 2020 the Company entered into a Share Exchange Agreement (“Agreement”) with Sapphire Biotech, Inc., a Delaware corporation (“Sapphire”) and all of the Sapphire stockholders (collectively, the “Sapphire Stockholders”). Following the closing of the transaction, Sapphire will become a wholly owned subsidiary of AXIM. Under the terms of the Agreement, the Company intends to assume the convertible notes in the principal amounts of $190,000. After the acquisition, the Convertible Note was able to convert 6,000,000 shares of Axim’s common stock. Upon assumption of the note, the Company recorded a beneficial conversion feature of $190,000. As of September 30, 2021 and December 31, 2020, the balance of secured convertible note was $199,991 and $195,716, which included $9,991 and $5,716 accrued interest, respectively. On July 21, 2020 the Company entered into convertible note purchase agreement with Cross & Company, the Company owed to Cross & Company $609,835 of aggregated payments and desired to satisfy the amount due in full by issuing to Cross & Company a convertible promissory note. The convertible note matures on July 21, 2032 and incurred 3.5% compounded interest paid annually. The Note are secured by the assets of the Company, may not be pre-paid without the consent of the holder, and are convertible at the option of the holder into shares of the Company common stock at a conversion price equal to $0.37. Notwithstanding the foregoing, holder shall not be permitted to convert the note, or portion thereof, if such conversion would result in beneficial ownership by holder and its affiliates of more than 4.9% of the debtor’s outstanding common stock as of the date of conversion. The Company determined that that the conversion of the amounts due into a long-term convertible note resulted in a debt extinguishment due to the change in the fair values exceeding 10%. Accordingly, the loss of $823,497 was included in the statement of operations as loss on debt extinguishment. As of September 30, 2021 and December 31, 2020, the balance of secured convertible note was $635,389 and $619,381, which included $25,554 and $9,546 accrued interest respectively. During the three and nine months ended September 30, 2021 and 2020, the Company amortized the debt discount on all the notes of $17,546, $220,578 and $22,313, $41,432, respectively, to other expenses. As of September 30, 2021 and December 31, 2020, unamortized debt discount was $623,095 and $843,673, respectively.

STOCK INCENTIVE PLAN

STOCK INCENTIVE PLAN	9 Months Ended
	Sep. 30, 2021
STOCK INCENTIVE PLAN
NOTE 12: STOCK INCENTIVE PLAN	NOTE 12: STOCK INCENTIVE PLAN On May 29, 2015 the Company adopted its 2015 Stock Incentive Plan. Under the Plan the Company may issue up to 10,000,000 S-8 shares to officers, employees, directors or consultants for services rendered to the Company or its affiliates or to incentivize such parties to continue to render services. S-8 shares are registered immediately upon the filing of the Plan and are unrestricted shares that are free-trading upon issuance. On May 20, 2021 the board consent increased the issue up to 20,000,000 shares. As of September 30, 2021 December 31, 2020 there were 8,739,285 and 9,806,000 shares available for issuance under the Plan. On May 13, 2020, Alim Seit-Nebi the Chief Technology Officer and Co-Founder of Sapphire Biotechnology was granted the options to purchase 1 million shares of Axim common stock under the plan at the exercise price of $0.126 per share. One third of the options will vest six months from the date of grant, one third of the options will vest one year from the date of grant, and the remaining one third of the options will vest two years from the date of grant. On May 13, 2020, Dr. Douglas Lake the Chief Clinical Officer and Co-Founder of Sapphire Biotechnology was granted the options to purchase 2 million shares of Axim common stock under the plan at the exercise price of $0.126 per share. One third of the options will vest six months from the date of grant, one third of the options will vest one year from the date of grant, and the remaining one third of the options will vest two years from the date of grant. On May 13, 2020, Timothy R, Scott the Director of Axim Biotechnology was granted the options to purchase 0.5 million shares of Axim common stock under the plan at the exercise price of $0.126 per share. One third of the options vested immediately, one third of the options will vest six months from the date of grant, and the remaining one third of the options will vest twelve months from the date of grant. On May 13, 2020, Robert Cunningham the Director of Axim Biotechnology was granted the options to purchase 0.5 million shares of Axim common stock under the plan at the exercise price of $0.126 per share. One third of the options vested immediately, one third of the options will vest six months from the date of grant, and the remaining one third of the options will vest twelve months from the date of grant. On May 13, 2020, Maurico Bellora the Director of Axim Biotechnology was granted the options to purchase 0.5 million shares of Axim common stock under the plan at the purchase price of $0.126 per share. One third of the options vested immediately, one third of the options will vest six months from the date of grant, and the remaining one third of the options will vest twelve months from the date of grant. On September 10, 2020, Noel C. Gillespie the Senior Patent Attorney of Axim Biotechnology was granted the options to purchase 0.5 million shares of Axim common stock under the plan at the purchase price of $0.61 per share. One third of the options vested immediately, one third of the options will vest one year from the date of grant, and the remaining one third of the options will vest two years from the date of grant. On August 2, 2021, Bijan Pedram the Senior Scientific of Sapphire Biotechnology was granted the options to purchase 0.1 million shares of Axim common stock under the plan at the purchase price of $0.67 per share. 25% of the Option shares will be vested upon the one anniversary of the vesting commencement day and the balance of the option shares will be vested of thirty-six (36) successive equal monthly in the first anniversary of the vesting commencement day. On August 17, 2021, Jeft Busby the Senior Vice president of Sales of Axim Biotechnology was granted the options to purchase 1 million of shares of Axim common stock under the plan at the purchase price of $0.60 per share. 25% of the Option shares will be vested upon the one anniversary of the vesting commencement day, 25% of the Option shares will be vested upon the two anniversaries of the vesting commencement day, 25% of the Option shares will be vested upon the three anniversary of the vesting commencement day and 25% of the Option shares will be vested upon the four anniversaries of the vesting commencement day. On September 1, 2021, Laura M. Periman Medical advisory board member of Axim Biotechnology was granted the options to purchase 0.1 million of shares of Axim common stock under the plan at the purchase price of $0.64 per share. 50% of the Option shares will be vested upon the one anniversary of the vesting commencement day and 50% of the Option shares will be vested upon the two anniversaries of the vesting commencement day. On September 4, 2021, Kelly K. Nichols Medical advisory Board member of Axim Biotechnology was granted the options to purchase 0.1 million of shares of Axim common stock under the plan at the purchase price of $0.62 per share. 50% of the Option shares will be vested upon the one anniversary of the vesting commencement day and 50% of the Option shares will be vested upon the two anniversaries of the vesting commencement day. On September 8, 2021, Joseph Tauber the Ophthalmic Chief Medical Officer (CMO) of Axim Biotechnology was granted the options to purchase 1 million of shares of Axim common stock under the plan at the purchase price of $0.622 per share. 25% of the Option shares will be vested upon the one anniversary of the vesting commencement day, 25% of the Option shares will be vested upon the two anniversaries of the vesting commencement day, 25% of the Option shares will be vested upon the three anniversary of the vesting commencement day and 25% of the Option shares will be vested upon the four anniversaries of the vesting commencement day. For the three and nine months ended September 30, 2021 and 2020 the Company recorded compensation expense of $761,810, $953,076 and $414,839, $235,000, respectively.

STOCKHOLDERS DEFICIT

STOCKHOLDERS DEFICIT	9 Months Ended
	Sep. 30, 2021
STOCKHOLDERS DEFICIT
NOTE 13: STOCKHOLDERS' DEFICIT	NOTE 13: STOCKHOLDERS’ DEFICIT Preferred Stock The Company has authorized 5,000,000 shares of preferred stock, with a par value of $0.0001 per share. Of the 5,000,000 authorized preferred shares, 4,000,000 are undesignated “blank check” preferred stock. The Company may issue such preferred shares and designate the rights, privileges and preferences of such shares at the time of designation and issuance. As of September 30, 2021, and December 31, 2020 there are -0- and -0- shares of undesignated preferred shares issued and outstanding, respectively. There are zero shares issued and outstanding of Series A and Series B Preferred stock as of September 30, 2021. Series C Convertible Preferred Stock On August 17, 2016 the Company designated up to 500,000 shares of a new Series C Convertible Preferred Stock (Series C Preferred Stock). The holders of the Series C Preferred are entitled to elect four members to the Company’s board of directors and are entitled to cast 100 votes per share on all other matters presented to the shareholders for a vote. Each share of Series C Convertible Preferred is convertible into one share of the Company’s common stock. The Series C Convertible Preferred designation contains a number of protective and restrictive covenants that restrict the Company from taking a number of actions without the prior approval of the holders of the Series C Preferred or the unanimous vote of all four Series C Directors. If at any time there are four Series C Directors, one such director must be independent as that term is defined in the Series C designation. Any challenge to the independence of a Series C Director is a right conferred only upon the holders of the Series B Convertible Preferred Stock and may only be made by the holders of the Series B Convertible Preferred Stock. On August 18, 2016 the Company issued all 500,000 shares of its newly designated Series C Preferred Stock to MJNA Investment Holdings, LLC in exchange for cash of $65,000. As the holders of the Series C Preferred Stock, MJNA Investment Holdings, LLC has designated Dr. Timothy R. Scott, John W. Huemoeller II, Robert Cunningham and Blake Schroeder as their four Series C Directors. On February 20, 2019, MJNA Investment Holdings LLC (“Seller”) sold its 500,000 shares of AXIM Biotechnologies, Inc.’s, a Nevada corporation (the “Company”) Series C Preferred Stock to Juniper & Ivy Corporation, a Nevada corporation (“Purchaser”) for a purchase price of $500,000 (the “Purchase Price”) pursuant to a Preferred Stock Purchase Agreement (the “Purchase Agreement”). Payment of the Purchase Price was made as follows (i) a $65,000 payment made by check payable to Seller, which Purchaser borrowed from an unrelated third-party and which has no recourse against the Series C Preferred Stock or assets of Purchaser (the “Loan”), and (ii) the issuance by Purchaser to Seller of a promissory note, face value, $435,000, which has no recourse against the Series C Preferred Stock or assets of Purchaser (the “Note”). The Company’s Chief Executive Officer John W. Huemoeller II is the President of Purchaser. Mr. Huemoeller provided a personal guaranty for the Loan and the Note. The holders of the Series C Preferred Stock are entitled to elect four members to the Company’s Board of Directors and are entitled to cast 100 votes per share on all other matters presented to the shareholders for a vote. As a result of this transaction, a change in control has occurred. Effective April 2, 2019, Blake N. Schroeder resigned as a member of the Company’s Board of Directors. Mr. Schroeder’s resignation was not because of any disagreements with the Company on matters relating to its operations, policies and practices. On April 3, 2019 pursuant to the Company’s Amended and Restated Bylaws, the holder of the Company’s Series C Preferred Stock appointed Mauricio Javier Gatto-Bellora to fill the director seat vacated by the resignation of Mr. Schroeder. On July 21, 2020 pursuant to the Company’s Amended and Restated Bylaws, the holder of the Company’s Series C Preferred Stock appointed Peter O’Rourke to fill one of the vacant positions on board created by the resignations of Dr. George Anastassov, Lekhram Changoer, and Dr. Philip Van Damme. Common Stock and Common Stock Warrants Common Stock The Company has authorized 300,000,000 shares of common stock, with a par value of $0.0001 per share. As of September 30, 2021, and December 31, 2020, the Company had 135,885,104 and 125,327,579 shares of common stock issued and outstanding, respectively. 2021 Transactions: Common Stock On July 29, 2021 the Company issued 122,000 restricted shares of its common stock to third party valued at $50,000 pursuant to the stock purchase agreement. The cash was received in 2021. During August and September 2021 the Company issued 1,060,715 commons shares and warrants to purchase 1,060,715 shares of common stock at an exercise price of $0.60 for gross cash proceeds of $297,000 pursuant to various Warrant Stock purchase agreements. The cash was received in the third quarter ending 2021. Warrants are exercisable within a 3 year period from issuance. During July and September 2021 the company issued 1,415,554 restricted shares of its common stock valued at $1,111,900 to third parties for certain services, recorded as consulting fees. In September 2021 the company issued 262,400 restricted shares of its common stock valued at $129,724 pursuant to S-1 Agreement to third party for cash, recorded as subscription receivable. Pursuant to its purchase of Advanced Tear Diagnostics, LLC the company has recorded 7,000,000 shares of its common stock to be issued valued at $4,270,000. Pursuant to a Stock purchase agreement the company has recorded 175,000 of its common shares to be issued valued at $52,500. On May 14, 2021, The Company entered into the Equity Purchase Agreement with Cross, pursuant to which we have the right to “put,” or sell, up to $10,000,000 worth of shares of our common stock to Cross. As provided in the Equity Purchase Agreement, we may require Cross to purchase shares of our common stock from time to time by delivering a put notice to Cross specifying the total number of shares to be purchased (such number of shares multiplied by the purchase price described below, the “Investment Amount”); provided there must be a minimum of ten trading days between delivery of each put notice. We may determine the Investment Amount, provided that such amount may not be more than 500% of the average daily trading volume in dollar amount for our common stock during the five trading days preceding the date on which we deliver the applicable put notice, unless waived by Cross in its sole discretion. Additionally, such amount may not be lower than $10,000 or higher than $1,000,000. Cross will have no obligation to purchase shares under the Equity Line to the extent that such purchase would cause Cross to own more than 4.99% of our issued and outstanding shares of common stock. In June 2021 the company issued 500,000 restricted shares of its common stock valued at $332,500 pursuant to S-1 Agreement to third party recorded as subscription receivable. Actual proceeds were $228,812. The difference of $103,688 was adjusted to additional paid in capital and was calculated in accordance with the S-1 agreement. During April, May and June 2021 the company issued 2,647,464 restricted shares of its common stock valued at $2,117,971 pursuant to conversion of convertible note and accrued interest of $582,707(Note 12) with a loss on extinguishment of debt $1,535,264. During April, May and June 2021 the Company issued 1,234,113 shares for cash of gross proceed of $402,500 pursuant to various Warrant Stock purchase agreements. The cash was received in the second quarter ending 2021. Out of these 519,828 shares of common stock valued at $152,500 was adjusted with common stock to be issued of prior period. The company also issued warrants to purchase 175,000 shares of common stock at an exercise price of $0.75 and 714,285 shares of common stock at an exercise price of $0.80. Warrants are exercisable within a 3 year period from issuance. During April, May and June 2021 the company issued 1,114,351 restricted shares of its common stock valued at $792,389 to third parties for certain services, recorded as consulting fees. During March 2021 the Company issued 1,712,500 shares for cash of gross $434,000 pursuant to various Stock purchase agreements. The cash was received in the first quarter ending 2021. The company also issued warrants to purchase 900,000 shares of common stock at an exercise price of $0.75. Warrants are exercisable within a 3 year period from issuance. Company paid finders fees of $20,000 in cash during this period for capital raise and will also issue shares equaling $16,000 in market value, which was issued during the three months ended September 30, 2021. On March 18, 2021 the company issued 488,428 restricted shares of its common stock valued at $291,974 to third parties for certain services, recorded as consulting fees. Out of these 108,965 shares of common stock valued at $66,974 was adjusted with common stock to be issued of prior year. 2020 Transactions: During the period between January 1, 2020 and December 31, 2020 the Company issued total 17,292,751 shares valued $3,309,130 pursuant to the Company’s Registration Statement on Form S-3. The Company received $3,309,130 in cash. On January 13, 2020 the Company issued 250,000 restricted shares of its common stock to third party valued at $50,000, which were carried on the books as stock to be issued. On January 23, 2020 and February 26, 2020 the Company issued 600,000, and 62,839 restricted shares of its common stock to third party valued at $262,500, and $25,000 pursuant to the stock purchase agreement for certain services, recorded as advertising and promotion expense and License, permits & Patents, respectively. On March 17, 2020 the company acquired 100% of the issued and outstanding shares of Sapphire by means of a share exchange with the Sapphire Stockholders in exchange for 54,000,000 restricted shares of its common stock at valued $7,506,000. On April 21, 2020 the Company issued 1,176,470 restricted shares of its common stock to third party valued at $100,000 pursuant to the stock purchase agreement. The cash was received in 2020. On May 6, 2020, the Company entered into an agreement with Sanammad Foundation, the Sanammad Parties agreed to forfeit and assign back to treasury, for no consideration, a total of 18,570,356 shares of the Company’s common stock, for which the fair value was $2,562,709, however for accounting purpose this transaction recording at par value adjustment to additional paid in capital. This transaction is related to the divesture of the previous operations to Sanammad. On May 22, 2020 the Company issued 190,810 and 286,215 S-8 shares valued at $60,000 and $90,000 pursuant to the Company’s Registration Statement on Form S-8 for severance fees. On June 10, 2020 and June 24, 2020 the Company issued 2,173,913 and 625,000 restricted shares of its common stock to third party valued at $500,000 and $100,000 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 1, 2020 the Company issued 185,185 and 370,370 restricted shares of its common stock to third party valued at $25,000 and $50,000 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 2, 2020 and July 9, 2020 the Company issued 714,285 and 1,785,714 restricted shares of its common stock to third party valued at $100,000 and $250,000 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 10, 2020 the Company issued 5,141,377 restricted shares of its common stock in exchange for the conversion of $51,414 of a convertible note payable, which included $6,414 in interest. On July 10, 2020 the Company issued 142,857 and 357,153 restricted shares of its common stock to third party valued at $20,000 and $50,000 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 10, 2020 the Company issued 250,000 and 107,143 restricted shares of its common stock to third party valued at $35,000 and $15,000 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 14, 2020 the Company issued 200,000 restricted shares of its common stock to third party valued at $23,630 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 21, 2020 the Company entered into convertible note purchase agreement with Cross & Company, the Company owed to Cross & Company $609,835 of aggregated payments due to subscription price adjustment and desired to satisfy the amount due in full by issuing to Cross & Company a convertible promissory note (see note 10). On July 22, 2020 the Company issued 65,359 and 130,719 restricted shares of its common stock to third party valued at $20,000 and $40,000 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 22, 2020 the Company issued 163,398 and 326,797 restricted shares of its common stock to third party valued at $50,000 and $100,000 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 22, 2020 the Company issued 816,993 and 65,359 restricted shares of its common stock to third party valued at $250,000 and $20,000 pursuant to the stock purchase agreement. The cash was received in 2020, respectively. On July 24, 2020 359,524 shares for the purchase of prepaid marketing expenses valued at $302,000 On August 4, 2020 the Company issued 141,243 restricted shares of its common stock to third party valued at $50,000 pursuant to the stock purchase agreement. The cash was received in 2020. On August 6, 2020 the Company issued 148,166 and 166,686 S-8 shares valued at $120,000 and $135,000 pursuant to the Company’s Registration Statement on Form S-8 for severance fees. On August 12, 2020 the Company issued 414,419 restricted shares of its common stock to third party valued at $76,690 pursuant to the stock purchase agreement for certain services, recorded as commission fees. On December 7, 2020 the Company issued 130,609 S-8 shares of its common stock to third party value at $75,000 pursuant to the Company’s Registration Statement on Form S-8 for severance fees.

STOCK OPTIONS AND WARRANTS

STOCK OPTIONS AND WARRANTS	9 Months Ended
	Sep. 30, 2021
STOCK OPTIONS AND WARRANTS
NOTE 14: STOCK OPTIONS AND WARRANTS	NOTE 14: STOCK OPTIONS AND WARRANTS Options to purchase common stock are granted at the discretion of the Board of Directors, a committee thereof or, subject to defined limitations, an executive officer of the Company to whom such authority has been delegated. Options granted to date generally have a contractual life of ten years. The stock option activity for nine months ended September 30, 2021 and the year ended December 31, 2020 is as follows: Options Outstanding Weighted Average Exercise Price Outstanding at December 31, 2019 2,000,000 $ 0.75 Granted 8,300,000 0.27 Exercised - - Expired or canceled - - Outstanding at December 31, 2020 10,300,000 0.36 Granted 2,960,715 0.60 Exercised - - Expired or canceled (2,000,000 ) 0.75 Outstanding at September 30, 2021 11,260,715 $ 0.36 The following table summarizes the changes in options outstanding, option exercisability and the related prices for the shares of the Company’s common stock issued to employees and consultants under a stock option plan at September 30, 2021 and December 31, 2020:2,000,000options issued to John Huemoeller were canceled to allow for issuances to other employees. As of September 30, 2021 Options Outstanding Options Exercisable Weighted Average Exercise Price ($) Number Outstanding Weighted Average Remaining Contractual Life (Years) Weighted Average Exercise Price ($) Number Exercisable Weighted Average Exercise Price ($) $ 0.36 11,260,715 8.5 $ 0.36 8,227,380 $ 0.36 As of December 31, 2020 Options Outstanding Options Exercisable Weighted Average Exercise Price ($) Number Outstanding Weighted Average Remaining Contractual Life (Years) Weighted Average Exercise Price ($) Number Exercisable Weighted Average Exercise Price ($) $ 0.36 10,300,000 9.8 $ 0.36 7,466,662 $ 0.36 The Company determined the value of share-based compensation for options vested using the Black-Scholes fair value option-pricing model with the following weighted average assumptions: September 30, December 31, 2021 2020 Expected life (years) 10 10 Risk-free interest rate (%) 1.74 0.61 Expected volatility (%) 190 230 Dividend yield (%) - - Weighted average fair value of shares at grant date $ 1.74 $ 0.61 For the three months ended September 30, 2021 and 2020 stock-based compensation expense related to vested options was $761,810 and $0, respectively. For the nine months ended September 30, 2021 and 2020 stock-based compensation expense related to vested options was $953,076 and $779,029, respectively. Warrants The following table summarizes warrant activity during the nine months ended September 30, 2021: Number of Warrants Weighted Average Exercise Price Outstanding at December 31, 2020 - $ - Granted 2,850,000 0.71 Forfeited/Cancelled - - Exercised - - Outstanding at September 30, 2021 2,805,000 $ 0.71 All outstanding warrants are exercisable at September 30, 2021 and there was no unrecognized stock-based compensation expense related to warrants. During the nine months ended September 30, 2020 there was no warrant activity.

DISCONTINUED OPERATIONS

DISCONTINUED OPERATIONS	9 Months Ended
	Sep. 30, 2021
DISCONTINUED OPERATIONS
NOTE 15: DISCONTINUED OPERATIONS	NOTE 15: DISCONTINUED OPERATIONS During May 2020 the Company decided to discontinue most of its operating activities pursuant to the Separation Agreement entered into by and among the Company, CanChew License Company (“CanCo”), CanChew Biotechnologies, LLC (“CanChew”), Medical Marijuana, Inc., Dr. George A. Anastassov (“Dr. Anastassov”), Dr. Philip A. Van Damme (“Dr. Van Damme”), Lekhram Changoer (“Mr. Changoer”), Sanammad Foundation, Netherlands and Sanammad Foundation, US (collectively, the “Sanammad Parties”). (see Note 1) Pursuant to the terms of the Purchase Agreement dated as of May 6, 2020, Sanammad Parties agreed to acquire from the Company substantially all of its assets and its wholly-owned subsidiaries and to assume certain liabilities and its wholly-owned subsidiaries. Sanammad Parties agreed to pay a purchase price of $2,609,100 reflected in amount due Canchew were deemed paid in full. The sale, which was completed on May 6, 2020, did not include the Company’s cash and certain other excluded assets and liabilities. The assets sold and liabilities transferred in the transaction were the sole revenue generating assets of the Company. The results of operations associated with the assets sold have been reclassified into discontinued operations for periods prior to the completion of the transaction. The following is a summary of assets and liabilities sold, stock retired and gain recognized, in connection with the sale of assets to Sanammad parties: Other current assets $ 5,000 Total current assets $ 510,017 Intangible assets, net of amortization $ 47,375 Total asset $ 562,392 Notes payable $ 880,000 Accounts payable and accrued expenses $ 210,640 Due to Canchew $ 1,526,603 Stock retired $ 1,857 Total liabilities and equity $ 2,619,100 The gain on sale of assets was reported during the period was determined as follows: Loss on sale of assets $ 562,392 Gain on sale of liabilities $ 2,619,100 Net gain from sale of assets and liabilities $ 2,056,708 The resulting gain from the sale will be fully offset by existing net operating loss carryforwards available to the Company. For the nine months ended September 30, 2021 and 2020 the Company recognized interest expense of $-0- and $-0-, respectively. Additionally, the operating results and cash flows related to assets sold on May 06, 2020 are included in discontinued operations in the consolidated statements of operations and consolidated statements of cash flows for the twelve months ended December 31, 2020 and 2019. As of September 30, 2021 and 2020, the Company has nil asset and liabilities of the discontinued operations in the unaudited condensed consolidated balance sheet in accordance with the provision of ASC 205-20. Loss from Discontinued Operations The sale of the majority of the assets and liabilities related to the Sanammad parties represents a strategic shift in the Company’s business. For this reason, the results of operations related to the assets and liabilities held for sale for all periods are classified as discontinued operations. The following is a summary of the results of operations related to the assets and liabilities held for sale (discontinued operations) for the nine months ended September 30, 2021 and 2020: September 30, 2021 September 30, 2020 Net sales $ - $ 5,097 Total expenses $ (4,633 ) $ (1,935,278 ) Gain from sale of asset and liability $ - $ 2,046,708 Other (loss) income $ - $ (87,383 ) (Loss) income from discontinued operations $ (4,633 ) $ 29,144 The following is a summary of net cash provided by or used in operating activities, investing activities and financing activities for the assets and liabilities held for sale (discontinued operations) for the nine months ended September 30, 2021 and 2020: September 30, 2021 September 30, 2020 Net (loss) income from discontinued operations $ (4,633 ) $ 29,144 Adjustment of non-cash activities - (1,551,166 ) Decrease in accounts receivable - 315,843 Increase in inventory - (22,203 ) Increase in accounts payable and accrued expenses - 393,953 Net cash provided by (used in) operating activities $ (4,633 ) $ (834,429 ) Net cash provided by (used in) investing activities $ - $ - Net cash provided by (used in) financing activities $ - $ (65,000 )

COMMITMENT AND CONTINGENCIES

COMMITMENT AND CONTINGENCIES	9 Months Ended
	Sep. 30, 2021
COMMITMENT AND CONTINGENCIES
NOTE 16: COMMITMENT AND CONTINGENCIES	NOTE 16: COMMITMENT AND CONTINGENCIES On January 2, 2019 the Company entered into the term of Executive’s employment agreement, at a base salary of $10,000 per month with John W. Huemoeller II to serve as its Chief Executive Officer. The Company and Executive acknowledge and agree that Executive’s employment hereunder shall at all times be “at will,” which means that either Executive may resign at any time for any reason or for no reason, and that the Company may terminate Executive’s employment at any time for any reason or for no reason, in either case, subject to the applicable provisions of this Agreement. In further consideration for Executive’s services and subject to the approval of the Board, Executive will be granted an option to purchase 2,000,000 shares of the Company’s common stock (the “Option Shares”). The option will be subject to the terms and conditions applicable to stock options granted under the Company’s 2015 Stock Incentive Plan, as amended from time to time (the “Plan”), and as described in the Plan and the stock option agreement, which Executive will be required to sign. 50% of the Option Shares shall vest on the date of grant and the remaining 50% of the Option Shares shall vest on the 12- month anniversary of the grant date, subject to Executive’s continued employment by the Company. The exercise price per share will be equal to the fair market value per share on the date of grant, as determined by the last closing price of the Company’s common stock the day prior to grant. Beginning in October 2019, the board decided to increase CEO base salary to $35,000 per month. On April 24, 2017 the company entered into an employment agreement with Robert Malasek, its Chief Financial Officer and Secretary. The agreement does not have a set term and may be terminated at any time by the Company or Mr. Malasek with proper notice. The shares were issued in the 1 st Industry Sponsored Research Agreement— Sapphire entered into the Industry Sponsored Research Agreement (“SRA”) effective February 7, 2020 to test and confirm the inhibitory activity of SBI-183 (exclusively licensed on January 13, 2020) and SBI-183 analogs, including those synthesized by the Company. The testing will include cell-based in vitro assays, NMR binding studies and testing to determine if SBI-183 enhances the activity of cytotoxic drugs in vitro. Animal studies will also be conducted under the SRA. Specifically, SBI-183 analogs will be evaluated in a mouse model of triple negative breast cancer using human tumor xenografts. The work will be performed over a period of one year with the total cost of the SRA totaling $150,468 paid prior to acquisition. For the nine months ended September 30, 2021, the Company recorded research and development expenses of $216,282. On August 5, 2020 Sapphire was awarded a $395,880 phase I Small Business Innovation Research (SBIR) grant by the National Cancer Institute (NCI). The grant will support continued development of novel small molecules that inhibit the enzymatic activity of Quiescin Sulfhydryl Oxidase I (QSOX1) based on a lead compound. QSOX1 is a tumor-derived enzyme that is important for cancer growth, invasion and metastasis. Sapphire is conducting this research with technology it has exclusively licensed from Skysong Innovations, LLC, the intellectual property management company for Arizona State University. Sapphire will subcontract tumor biology work for evaluating analog inhibitors for QSOX1 to Dr. Doug Lake’s laboratory at Arizona State University and Mayo Clinic Arizona. Grant income received for the nine months ended September 30, 2021 and 2020 was $279,981 and $25,899; respectively. On August 25, 2020 we signed an exclusive licensing, manufacturing and distribution agreement with Empowered Diagnostics LLC to execute the high-volume production of our rapid point-of-care diagnostic test. AXIM and Empowered have completed the technology transfer and Empowered Diagnostics has built out their production facility to be able to manufacture millions of our neutralizing antibody tests for COVID-19 per month. In exchange for this license Empowered will pay Axim a royalty on net sales on all licensed products sold by Empowered covered by this license which global with the exception of Mexico. Operating Lease Lease Agreement—On March 3, 2020, Sapphire entered into a 3-year lease agreement (“Lease”) to relocate to a larger space within the same business park. The new space totals 1,908 square feet with monthly base rent in the 1st year $4,713, 2nd year $4,854 and 3rd year $5,000 at implicit interest rate of 6%. Upon commencement of the Lease on April 25, 2020, the previous lease will expire. Operating Leases - Right of Use Assets and Purchase Commitments Right of Use Assets We have operating leases for office space that expire through 2023. Below is a summary of our right of use assets and liabilities as of September 30, 2021. Right-of-use assets $ 90,630 Lease liability obligations, current $ 58,540 Lease liability obligations, noncurrent 32,090 Total lease liability obligations $ 90,630 Weighted-average remaining lease term 1.58 years Weighted-average discount rate 6 % The following table summarizes the lease expense for the nine months ended September 30, 2021 and 2020: September 30, September 30, 2021 2020 Operating lease expense $ 43,122 * $ 18,852 Short-term lease expense 11,545 15,313 Total lease expense $ 54,667 $ 34,165 *We recorded $54,667 of operating lease expense this includes $11,545 of maintenance charges. Approximate future minimum lease payments for our right of use assets over the remaining lease periods as of September 30, 2021, are as follows: Remainder of 2021 $ 14,562 2022 59,416 2023 20,000 Total minimum payments 93,978 Less: amount representing interest (3,348 ) Total $ 90,630 Litigation As of September 30, 2021, and this report issuing date, the Company is not a party to any pending material legal proceeding. To the knowledge of management, no federal, state or local governmental agency is presently contemplating any proceeding against the Company. To the knowledge of management, no director, executive officer or affiliate of the Company, any owner of record or beneficially of more than five percent of the Company’s Common Stock is a party adverse to the Company or has a material interest adverse to the Company in any proceeding.

SUBSEQUENT EVENTS

SUBSEQUENT EVENTS	9 Months Ended
	Sep. 30, 2021
SUBSEQUENT EVENTS
NOTE 17: SUBSEQUENT EVENTS	NOTE 17: SUBSEQUENT EVENTS On October 13, 2021 the company issued 118,000 restricted shares of its common stock valued at $70,800 to third party for certain services, recorded as advertising and promotion expense and License, permits & Patents, respectively. On October 19, 2021, the Company issued a total of 175,000 Common Stock Purchase Warrants (exercise price $0.30) to third party valued at $152,500. Pursuant to an extension approved by the Board of Directors on August 20, 2021, all Warrants shall be valid for 36 months from effective date included cashless exercise. The cash was received in 2021 for the purchase of the warrants. In October 2021, The Company concluded a Security Purchase Agreement with GS Capital Partners, pursuant to s to purchase and the Company desires to issue and sell, upon the terms and conditions set forth in this Agreement a 6% convertible note of the Company, in the form attached hereto as Exhibit A in the aggregate principal amount of $1,110,000.00 (together with any note(s) issued in replacement thereof or as a dividend thereon or otherwise with respect thereto in accordance with the terms thereof, the “Note”), convertible into shares of common stock, of the Company (the “Common Stock”), upon the terms and subject to the limitations and conditions set forth in such Note. The Note shall contain an original issue discount of $100,000.00 such that the purchase price of the Note shall be $1,010,000.

SIGNIFICANT ACCOUNTING POLICI_2

SIGNIFICANT ACCOUNTING POLICIES (Policies)	9 Months Ended
	Sep. 30, 2021
SIGNIFICANT ACCOUNTING POLICIES
Use of estimates	The preparation of the unaudited condensed consolidated financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements as well as the reported amounts of revenue and expenses during reporting periods. Actual results could differ from these estimates. Significant estimates are assumptions about collection of accounts receivable, intangible assets, useful life of intangible assets, determination of the discount rate for operating leases and assumptions used in Black-Scholes-Merton, or BSM, valuation methods, such as expected volatility, risk-free interest rate and expected dividend rate.
Risks and uncertainties	The Company operates in a dynamic and highly competitive industry and is subject to risks and uncertainties common to early-stage companies in the biotechnology industry, including, but not limited to, development by competitors of new technological innovations, protection of proprietary technology, dependence on key personnel, contract manufacturer and contract research organizations, compliance with government regulations and the need to obtain additional financing to fund operations. Product candidates currently under development will require significant additional research and development efforts, including extensive preclinical studies and clinical trials and regulatory approval, prior to commercialization. These efforts require significant amounts of additional capital, adequate personnel infrastructure and extensive compliance and reporting. The Company believes that changes in any of the following areas could have a material adverse effect on the Company’s future financial position, results of operations, or cash flows; ability to obtain future financing; advances and trends in new technologies and industry standards; results of clinical trials; regulatory approval and market acceptance of the Company’s products; development of sales channels; certain strategic relationships; litigation or claims against the Company based on intellectual property, patent, product, regulatory, or other factors; and the Company’s ability to attract and retain employees necessary to support its growth. Products developed by the Company require approvals from the U.S. Food and Drug Administration (“FDA”) or other international regulatory agencies prior to commercial sales. There can be no assurance that the Company’s research and development will be successfully completed, that adequate protection for the Company’s intellectual property will be obtained or maintained, that the products will receive the necessary approvals, or that any approved products will be commercially viable. If the Company was denied approval, approval was delayed or the Company was unable to maintain approval, it could have a materially adverse impact on the Company. Even if the Company’s product development efforts are successful, it is uncertain when, if ever, the Company will generate revenue from product sales. The Company operates in an environment of rapid change in technology and substantial competition from other pharmaceutical and biotechnology companies. In addition, the Company is dependent upon the services of its employees, consultants and other third parties. Beginning in late 2019, the outbreak of a novel strain of virus named SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), or coronavirus, which causes coronavirus disease 2019, or COVID-19, has evolved into a global pandemic. The extent of the impact of the coronavirus outbreak on the Company’s business will depend on certain developments, including the duration and spread of the outbreak and the extent and severity of the impact on the Company’s clinical trial activities, research activities and suppliers, all of which are uncertain and cannot be predicted. At this point, the extent to which the coronavirus outbreak may materially impact the Company’s financial condition, liquidity or results of operations is uncertain. The Company has expended and will continue to expend substantial funds to complete the research, development and clinical testing of product candidates. The Company also will be required to expend additional funds to establish commercial-scale manufacturing arrangements and to provide for the marketing and distribution of products that receive regulatory approval. The Company may require additional funds to commercialize its products. The Company is unable to entirely fund these efforts with its current financial resources. If adequate funds are unavailable on a timely basis from operations or additional sources of financing, the Company may have to delay, reduce the scope of or eliminate one or more of its research or development programs which would materially and adversely affect its business, financial condition and operations. There have been no material changes in the accounting policies from those disclosed in the financial statements and the related notes included in the Form 10-K.
Cash equivalents	The Company considers all highly liquid investments with original maturities of three months or less at the time of purchase to be cash equivalents. As of September 30, 2021 and December 31, 2020, the Company had no cash equivalents. Cash and cash equivalents are maintained at financial institutions and, at times, balances may exceed federally insured limits. The Company had no uninsured balances at September 30, 2021 and December 31, 2020. The Company has never experienced any losses related to these balances.
Accounts Receivable	It is the Company’s policy to review accounts receivable at least on monthly basis for conductibility and follow up with customers accordingly. COVID19 has slowed collection as our customers are in a mandated pause. The Company have geographic concentration of customers for the three months ending September 30, 2021 and 2020. There were no accounts receivable as of September 30, 2021’
Concentrations	At December 31, 2020, one customer accounted for 100% of accounts receivable. There were no accounts receivable as of September 30, 2021.
Inventory	Inventory consists of raw materials owned by the Company and are stated at the lower of cost or market. As of September 30, 2021 and December 31, 2020, the Company had $20,127 and $-0-; respectively.
Property and equipment	Property and equipment are carried at cost less accumulated depreciation. Depreciation is computed using straight-line method over the estimated useful life. New assets and expenditures that extend the useful life of property or equipment are capitalized and depreciated. Expenditures for ordinary repairs and maintenance are charged to operations as incurred. The Company’s property and equipment relating to continuing operations consisted of the following on September 30, 2021 and December 31, 2020, respectively, and none related to discontinued operations. September 30, December 31, 2021 2020 Equipment $ 154,809 $ 134,788 Less: accumulated depreciation $ 50,812 $ 30,694 $ 103,997 $ 104,094 For the nine months ended September 30, 2021 and 2020, the Company recognized depreciation expense of $20,119 and $10,497 respectively. For the three months ended September 30, 2021 and 2020, the Company recognized depreciation expense of $6,935 and $5,372, respectively.
In-Process Research and Development (IPR&D)	The fair value of IPR&D acquired through a business combination is capitalized as an indefinite-lived intangible asset until the completion or abandonment of the related research and development activities. When the related research and development is completed, the asset will be assigned a useful life and amortized. The fair value of an IPR&D intangible asset is determined using an income approach. This approach starts with a forecast of the net cash flows expected to be generated by the asset over its estimated useful life. The net cash flows reflect the asset’s stage of completion, the probability of technical success, the projected costs to complete, expected market competition, and an assessment of the asset’s life-cycle. The net cash flows are then adjusted to present value by applying an appropriate discount rate that reflects the risk factors associated with the cash flow streams. The product development related to the IPR&D acquired reached completion in April 2021.
Goodwill	Goodwill represents the excess of the purchase price of acquired businesses over the estimated fair value of the identifiable net assets acquired. Goodwill is not amortized but is tested for impairment at least annually at the reporting unit level or more frequently if events or changes in circumstances indicate that the asset might be impaired. Goodwill is tested for impairment annually or more frequently if events or changes in circumstances between annual tests indicate that the asset may be impaired. Impairment loss is recognized based on a comparison of the fair value of the asset to it carrying value, without consideration of any recoverability. Intangible Assets As required by generally accepted accounting principles, trademarks and patents are amortized if they have a definite life, the amortization is estimated in straight line through three years starting in April 2021. As a result of the acquisition of asset of Advanced Tear Diagnostic, LLC, we recognize patents and licenses, which are amortized in straight line over their remaining useful lives. The Company’s intangible assets relating to continuing operations and discontinued operations consisted of the following on September 30, 2021 and December 31, 2020, respectively. September 30, December 31, 2021 2020 Goodwill $ 2,458,233 $ 2,458,233 Intellectual Property (IPRD) 7,800,000 7,800,000 Patents 250,000 - Licenses 4,270,000 - 14,778,233 10,258,233 Less: accumulated amortization 1,333,954 - $ 13,444,279 $ 10,258,233 Estimated aggregate amortization expense for each of the three succeeding years ending December 31 is as follows: 2021 2022 2023 2024 Amortization expense $ 2,088,000 $ 2,990,000 $ 2,990,000 $ 1,040,000
Revenue Recognition	The Company follows the guidance contained in Topic 606 (FASB ASC 606). The core principle of Topic 606 (FASB ASC 606) is that an entity should recognize revenue to depict the transfer of goods of services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. The revenue recognition guidance contained in Topic 606, to follow the five-step revenue recognition model along with other guidance impacted by this standard: (1) identify the contract with the customer; (2) identify the performance obligations in the contract; (3) determine the transportation price; (4) allocate the transportation price; (5) recognize revenue when or as the entity satisfies a performance obligation. All revenue was from operations that were divested. Revenues are recognized when title for goods is transferred; non-refundable fees and proceeds from irrevocable agreements recognized when inflows or other enhancements of assets of the Company are received. Revenues from continuing operations recognized for three and nine months ended September 30, 2021 and 2020 amounted to $8,127, $55,651, $-0- and $-0-, respectively. Revenues from discontinued operations recognized for three and nine months ended September 30, 2021 and 2020 amounted to $-0-, $-0-, and $-0-, $7,990, respectively.
Collaboration Revenue	Revenue recognition for collaboration agreements will require significant judgment. The Company’s assessments and estimates are based on contractual terms, historical experience and general industry practice. Revisions in these values or estimations have the effect of increasing or decreasing collaboration revenue in the period of revision. On August 21, 2020, the Company entered into a Distribution, License and Supply Agreement (“License Agreement”) with Empowered Diagnostics, LLC ("Empowered Diagnostics”"). The License Agreement has a term of xx years and provides Empowered Diagnostics with a right to commercialize The company’s products worldwide with the exception of Mexico. Under the License Agreement, the company is responsible for applying for and obtaining necessary regulatory approvals in the US and EU, as well as marketing, sales and distribution of the products. Empowered Diagnostics will pay a transfer price for all licensed products, and upon achievement of certain regulatory and sales milestones, the Company may receive payments from Empowered Diagnostics equal to 8% of the monthly gross revenue. Agreement continues until terminated by mutual consent or uncorrected breach.
Grant Income	In 2021 the Company has received government grants to drive its research and development efforts. Through these government grants, the government has provided funding for the Company to perform research and development activities which will assist in developing its products. The Company believes the government entities funding these grants are interested in the Company advancing its underlying technologies through research activities and not providing incentives for hiring employees or building facilities that would suggest that the grant monies are not for specific research activities. In determining how to classify the monies received under government grants, the Company acknowledges that there is no specific guidance under US GAAP and that the FASB and AICPA have often drawn upon the guidance in IAS 20 for classification. In considering the alternatives provided by IAS 20 for the presentation of these grants in the Company’s financial statements, the Company believes that recognizing the government grant proceeds as a component of other revenue is a better reflection of the economics of the arrangements as the Company earns the funding through the performance of research and development which is not one of the Company’s primary business activities or central to its operations. The Company believes that presenting research and development funding from government grants, as other revenue provides consistency in our financial reporting. The Company also believes that this presentation clearly presents to users of its financial statements in one line the Company’s sources of funding from these grants. The Company notes that there are no contingencies associated with the receipt of or ability to retain the funds under the grant, other than undertaking and performing the related research and development activities. The Company recognizes funds received from contractual research and development services and from government grants as other revenue. These contracts and grants are not considered an ongoing major and central operation of the Company’s business. Our Income from Grants from Government for the three and nine months ended September 30, 2021 and 2020, was $59,986, $279,981 and $25,899, $25,899 respectively.
Cost of Sales	Cost of sales includes the purchase cost of products sold and all costs associated with getting the products to the customers including buying and transportation costs. Cost of sales all related to discontinued operations.
Shipping Costs	Shipping and handling costs billed to customers are recorded in sales. Shipping costs incurred by the company are recorded in general and administrative expenses. Shipping costs all related to discontinued operations.
Fair Value Measurements	The Company applies the guidance that is codified under ASC 820-10 related to assets and liabilities recognized or disclosed in the financial statements at fair value on a recurring basis. ASC 820-10 defines fair value, establishes a framework for measuring fair value and expands disclosures about fair value measurements.
Convertible Instruments	The Company evaluates and accounts for conversion options embedded in its convertible instruments in accordance with professional standards for “Accounting for Derivative Instruments and Hedging Activities.” Professional standards generally provide three criteria that, if met, require companies to bifurcate conversion options from their host instruments and account for them as free-standing derivative financial instruments. These three criteria include circumstances in which (a) the economic characteristics and risks of the embedded derivative instruments are not clearly and closely related to the economic characteristics and risks of the host contract, (b) the hybrid instrument that embodies both the embedded derivative instrument and the host contract is not re-measured at fair value under otherwise applicable generally accepted accounting principles with changes in fair value reported in earnings as they occur and (c) a separate instrument with the same terms as the embedded derivative instrument would be considered a derivative instrument. Professional standards also provide an exception to this rule when the host instrument is deemed to be conventional as defined under professional standards as “The Meaning of “Conventional Convertible Debt Instrument.” The Company accounts for convertible instruments (when it has determined that the embedded conversion options should not be bifurcated from their host instruments) in accordance with professional standards when “Accounting for Convertible Securities with Beneficial Conversion Features,” as those professional standards pertain to “Certain Convertible Instruments.” Accordingly, the Company records, when necessary, discounts to convertible notes for the intrinsic value of conversion options embedded in debt instruments based upon the differences between the fair value of the underlying common stock at the commitment date of the note transaction and the effective conversion price embedded in the note. Debt discounts under these arrangements are amortized over the term of the related debt to their earliest date of redemption. The Company also records when necessary deemed dividends for the intrinsic value of conversion options embedded in preferred shares based upon the differences between the fair value of the underlying common stock at the commitment date of the note transaction and the effective conversion price embedded in the note. ASC 815-40 provides that, among other things, generally, if an event is not within the entity’s control could or require net cash settlement, then the contract shall be classified as an asset or a liability.
Income Taxes	The Company follows Section 740-10, Income tax (“ASC 740-10”) Fair Value Measurements and Disclosures of the FASB Accounting Standards Codification, which requires recognition of deferred tax assets and liabilities for the expected future tax consequences of events that have been included in the financial statements or tax returns. Under this method, deferred tax assets and liabilities are based on the differences between the financial statement and tax bases of assets and liabilities using enacted tax rates in effect for the year in which the differences are expected to reverse. Deferred tax assets are reduced by a valuation allowance to the extent management concludes it is more likely than not that the assets will not be realized. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in the Statements of Operations in the period that includes the enactment date. The Company recognizes deferred tax assets to the extent that the Company believes that these assets are more likely than not to be realized. In making such a determination, the Company considers all available positive and negative evidence, including reversals of any existing taxable temporary differences, projected future taxable income, tax planning strategies, and the results of recent operations. If the Company determines that it would be able to realize a deferred tax asset in the future in excess of any recorded amount, the Company would make an adjustment to the deferred tax asset valuation allowance, which would reduce the provision for income taxes. The Company adopted section 740-10-25 of the FASB Accounting Standards Codification (“Section 740-10-25”). Section 740-10-25 addresses the determination of whether tax benefits claimed or expected to be claimed on a tax return should be recorded in the financial statements. Under Section 740-10-25, the Company may recognize the tax benefit from an uncertain tax position only if it is more likely than not that the tax position will be sustained on examination by the taxing authorities, based on the technical merits of the position. The tax benefits recognized in the financial statements from such a position should be measured based on the largest benefit that has a greater than fifty percent (50%) likelihood of being realized upon ultimate settlement. Section 740-10-25 also provides guidance on de-recognition, classification, interest and penalties on income taxes, accounting in interim periods and requires increased disclosures. The Company had no liabilities for unrecognized income tax benefits according to the provisions of Section 740-10-25.
Concentrations of Credit Risk	Financial instruments and related items, which potentially subject the Company to concentrations of credit risk, consist primarily of cash and cash equivalents. The Company places its cash and temporary cash investments with credit quality institutions. At times, such amounts may be in excess of the FDIC insurance limit.
Net Loss per Common Share	Net loss per common share is computed pursuant to section 260-10-45 Earnings Per Share (“ASC 260-10”) of the FASB Accounting Standards Codification. Basic net loss per share is computed by dividing net loss by the weighted average number of shares of common stock outstanding during the period. Diluted net loss per share is computed by dividing net loss by the weighted average number of shares of common stock outstanding and the member potentially outstanding during each period. In periods when a net loss is experienced, only basic net loss per share is calculated because to do otherwise would be anti-dilutive. There were 30,530,216 common share equivalents at September 30, 2021 and 32,556,727 common shares at December 31, 2020. For the nine months ended September 30, 2021 and 2020 these potential shares were excluded from the shares used to calculate diluted earnings per share as their inclusion would reduce net loss per share.
Stock Based Compensation	All stock-based payments to employees and to nonemployee directors for their services as directors, including any grants of restricted stock and stock options, are measured at fair value on the grant date and recognized in the statements of operations as compensation or other expense over the relevant service period. Stock-based payments to nonemployees are recognized as an expense over the period of performance. Such payments are measured at fair value at the earlier of the date a performance commitment is reached, or the date performance is completed. In addition, for awards that vest immediately and are non-forfeitable the measurement date is the date the award is issued. The Company accounts for stock options issued to non-employees based on the estimated fair value of the awards using the Black-Scholes option pricing model in accordance with ASC 505-50, Equity-Based Payment to Non-employees
Research and Development	The Company accounts for research and development costs in accordance with the Accounting Standards Codification subtopic 730-10, Research and Development (“ASC 730-10”). Under ASC 730-10, all research and development costs must be charged to expense as incurred. Accordingly, internal research and development costs are expensed as incurred. Third-party research and development costs are expensed when the contracted work has been performed or as milestone results have been achieved. Company-sponsored research and development costs related to both present and future products are expensed in the period incurred. For the three and nine months ended September 30, 2021 and 2020 the Company incurred research and development expenses of $67,263, $216,282 and $109,139, $235,431 from continuing operations, respectively. For the three and nine months ended September 30, 2021 and 2020 the Company incurred research and development expenses of $-0-, $-0- and $(400,417), $426,665 from discontinued operations, respectively. The Company has entered into various agreements with CROs. The Company’s research and development accruals are estimated based on the level of services performed, progress of the studies, including the phase or completion of events, and contracted costs. The estimated costs of research and development provided, but not yet invoiced, are included in accrued liabilities on the balance sheet. If the actual timing of the performance of services or the level of effort varies from the original estimates, the Company will adjust the accrual accordingly. Payments made to CROs under these arrangements in advance of the performance of the related services are recorded as prepaid expenses and other current assets until the services are rendered.
Recently Issued Accounting Standards	Accounting Standards Implemented Since December 31, 2020 ASC Update 2021-04 Earnings Per Share (Topic 260), Debt—Modifications and Extinguishments (Subtopic 470-50), Compensation—Stock Compensation (Topic 718), and Derivatives and Hedging—Contracts in Entity’s Own Equity (Subtopic 815-40): Issuer’s Accounting for Certain Modifications or Exchanges of Freestanding Equity-Classified Written Call Options (a consensus of the FASB Emerging Issues Task Force) The amendments in this Update affect all entities that issue freestanding written call options that are classified in equity. Specifically, the amendments affect those entities when a freestanding equity-classified written call option is modified or exchanged and remains equity classified after the modification or exchange. The amendments that relate to the recognition and measurement of EPS for certain modifications or exchanges of freestanding equity-classified written call options affect entities that present EPS in accordance with the guidance in Topic 260, Earnings Per Share. The amendments in this Update do not apply to modifications or exchanges of financial instruments that are within the scope of another Topic. That is, accounting for those instruments continues to be subject to the requirements in other Topics. The amendments in this Update do not affect a holder’s accounting for freestanding call options. ASC Update No. 2020-10 In October 2020, the FASB issued ASC Update No. 2020-10, Codification Improvements. Update No. 2020-10 amends a wide variety of Topics in the Codification in order to improve the consistency of the Codification and the application thereof, while leaving Generally Accepted Accounting Principles unchanged. ASC Update No. 2020-06 In August 2020, the FASB issued ASC Update No. 2020-06, Debt – Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging – Contracts in Entity’s Own Equity (Subtopic 815-40): Accounting for Convertible Instruments and Contracts in an Entity’s Own Equity. The amendments in Update No. 2020-06 simplify the complexity associated with applying U.S. GAAP for certain financial instruments with characteristics of liabilities and equity. More specifically, the amendments focus on the guidance for convertible instruments and derivative scope exception for contracts in an entity’s own equity Other recent accounting pronouncements issued by the FASB and the SEC did not or are not believed by management to have a material impact on the Company’s present or future consolidated financial statements.

ACQUISITION OF SAPPHIRE BIOTE_2

ACQUISITION OF SAPPHIRE BIOTECH, INC. (Tables)	9 Months Ended
	Sep. 30, 2021
ACQUISITION OF SAPPHIRE BIOTECH, INC.
Schedule of consideration paid	Consideration: Cash and cash equivalents $ 79,814 Property and equipment, net 20,533 In process Research & Development (IPRD) 7,800,000 Goodwill 2,458,233 Security deposit 12,785 Total asset acquired $ 10,371,365 Accrued expenses and other current liabilities $ 5,767 Deferred taxes liability 2,340,000 Notes Payable including convertible and discount on conversion 519,598 Total liabilities assumed $ 2,865,365 Net assets acquired $ 7,506,000

SIGNIFICANT ACCOUNTING POLICI_3

SIGNIFICANT ACCOUNTING POLICIES (Tables)	9 Months Ended
	Sep. 30, 2021
SIGNIFICANT ACCOUNTING POLICIES
Schedule of property and equipment relating to continuing operations	September 30, December 31, 2021 2020 Equipment $ 154,809 $ 134,788 Less: accumulated depreciation $ 50,812 $ 30,694 $ 103,997 $ 104,094
Schedule of intangible assets	September 30, December 31, 2021 2020 Goodwill $ 2,458,233 $ 2,458,233 Intellectual Property (IPRD) 7,800,000 7,800,000 Patents 250,000 - Licenses 4,270,000 - 14,778,233 10,258,233 Less: accumulated amortization 1,333,954 - $ 13,444,279 $ 10,258,233
Estimated aggregate amortization expense	2021 2022 2023 2024 Amortization expense $ 2,088,000 $ 2,990,000 $ 2,990,000 $ 1,040,000

PREPAID EXPENSES (Tables)

PREPAID EXPENSES (Tables)	9 Months Ended
	Sep. 30, 2021
PREPAID EXPENSES
Schedule of Prepaid Expenses	September 30, December 31, 2021 2020 Prepaid insurance $ 96,881 $ 45,983 Prepaid services 44,661 209,940 $ 141,542 $ 255,923

CONVERTIBLE NOTES PAYABLE (Tabl

CONVERTIBLE NOTES PAYABLE (Tables)	9 Months Ended
	Sep. 30, 2021
CONVERTIBLE NOTES PAYABLE
Schedule of Convertible Note Payable of Related Party	September 30, December 31, 2021 2020 Convertible note payable, due on November 1, 2026, interest at 3.5% p.a. $ 4,000,000 $ 4,000,000 Accrued interest 264,037 158,648 Convertible note payable, net $ 4,264,037 $ 4,158,648
Schedule of Convertible Notes Payable, Shareholder	September 30, December 31, 2021 2020 Convertible note payable, due on October 1, 2029, interest at 3.5% p.a. $ 484,478 $ 484,478 Convertible note payable, due on October 1, 2029, interest at 3.5% p.a. 500,000 1,000,000 Convertible note payable, due on December 31, 2034, interest at 3% p.a. 190,000 190,000 Convertible note payable, due on July 21, 2032, interest at 3.5% p.a. 609,835 609,835 Accrued interest (The accrued interest and principal are both included in the captions titled “convertible note payable” in the balance sheet) 208,089 236,148 Total 1,992,402 2,520,461 Less: unamortized debt discount/finance premium costs (623,095 ) (843,673 ) Convertible note payable, net $ 1,369,307 $ 1,676,788

STOCK OPTIONS AND WARRANTS (Tab

STOCK OPTIONS AND WARRANTS (Tables)	9 Months Ended
	Sep. 30, 2021
STOCK OPTIONS AND WARRANTS
Schedule of Stock option activity	Options Outstanding Weighted Average Exercise Price Outstanding at December 31, 2019 2,000,000 $ 0.75 Granted 8,300,000 0.27 Exercised - - Expired or canceled - - Outstanding at December 31, 2020 10,300,000 0.36 Granted 2,960,715 0.60 Exercised - - Expired or canceled (2,000,000 ) 0.75 Outstanding at September 30, 2021 11,260,715 $ 0.36
Schedule of options under Stock Option Plan	Options Outstanding Options Exercisable Weighted Average Exercise Price ($) Number Outstanding Weighted Average Remaining Contractual Life (Years) Weighted Average Exercise Price ($) Number Exercisable Weighted Average Exercise Price ($) $ 0.36 11,260,715 8.5 $ 0.36 8,227,380 $ 0.36 Options Outstanding Options Exercisable Weighted Average Exercise Price ($) Number Outstanding Weighted Average Remaining Contractual Life (Years) Weighted Average Exercise Price ($) Number Exercisable Weighted Average Exercise Price ($) $ 0.36 10,300,000 9.8 $ 0.36 7,466,662 $ 0.36
Schedule of assumptions to determine value of share-based compensation for options	September 30, December 31, 2021 2020 Expected life (years) 10 10 Risk-free interest rate (%) 1.74 0.61 Expected volatility (%) 190 230 Dividend yield (%) - - Weighted average fair value of shares at grant date $ 1.74 $ 0.61
Schedule Of Warrants	Number of Warrants Weighted Average Exercise Price Outstanding at December 31, 2020 - $ - Granted 2,850,000 0.71 Forfeited/Cancelled - - Exercised - - Outstanding at September 30, 2021 2,805,000 $ 0.71

DISCONTINUED OPERATIONS (Tables

DISCONTINUED OPERATIONS (Tables)	9 Months Ended
	Sep. 30, 2021
DISCONTINUED OPERATIONS
Schedule of Discontinued Operations - Summary of assets and liabilities sold	Other current assets $ 5,000 Total current assets $ 510,017 Intangible assets, net of amortization $ 47,375 Total asset $ 562,392 Notes payable $ 880,000 Accounts payable and accrued expenses $ 210,640 Due to Canchew $ 1,526,603 Stock retired $ 1,857 Total liabilities and equity $ 2,619,100 The gain on sale of assets was reported during the period was determined as follows: Loss on sale of assets $ 562,392 Gain on sale of liabilities $ 2,619,100 Net gain from sale of assets and liabilities $ 2,056,708
Summary of Results of Discontinued Operations	September 30, 2021 September 30, 2020 Net sales $ - $ 5,097 Total expenses $ (4,633 ) $ (1,935,278 ) Gain from sale of asset and liability $ - $ 2,046,708 Other (loss) income $ - $ (87,383 ) (Loss) income from discontinued operations $ (4,633 ) $ 29,144 The following is a summary of net cash provided by or used in operating activities, investing activities and financing activities for the assets and liabilities held for sale (discontinued operations) for the nine months ended September 30, 2021 and 2020: September 30, 2021 September 30, 2020 Net (loss) income from discontinued operations $ (4,633 ) $ 29,144 Adjustment of non-cash activities - (1,551,166 ) Decrease in accounts receivable - 315,843 Increase in inventory - (22,203 ) Increase in accounts payable and accrued expenses - 393,953 Net cash provided by (used in) operating activities $ (4,633 ) $ (834,429 ) Net cash provided by (used in) investing activities $ - $ - Net cash provided by (used in) financing activities $ - $ (65,000 )

COMMITMENT AND CONTINGENCIES (T

COMMITMENT AND CONTINGENCIES (Tables)	9 Months Ended
	Sep. 30, 2021
COMMITMENT AND CONTINGENCIES
Summary of Lease Expenses	September 30, September 30, 2021 2020 Operating lease expense $ 43,122 * $ 18,852 Short-term lease expense 11,545 15,313 Total lease expense $ 54,667 $ 34,165
Schedule of Future Minimum Rental Payments for Operating Leases	Remainder of 2021 $ 14,562 2022 59,416 2023 20,000 Total minimum payments 93,978 Less: amount representing interest (3,348 ) Total $ 90,630
Summary of Right of Use Assets and Liabilities	Right-of-use assets $ 90,630 Lease liability obligations, current $ 58,540 Lease liability obligations, noncurrent 32,090 Total lease liability obligations $ 90,630 Weighted-average remaining lease term 1.58 years Weighted-average discount rate 6 %

ORGANIZATION (Details Narrative

ORGANIZATION (Details Narrative) - USD ($)	May 11, 2015	Mar. 17, 2020
Acquisition ownership percentage	100.00%
Acquisition of common stock shares	5,826,706	6,000,000
Consideration for payment	$ 65,000
Total amount paid inconsideration	$ 2,610,000
Series B Preferred Stock [Member]
Acquisition ownership percentage	100.00%
Acquisition of common stock shares	18,570,356

ACQUISITION OF SAPPHIRE BIOTE_3

ACQUISITION OF SAPPHIRE BIOTECH INC (Details) - Sapphire [Member]	Mar. 17, 2021USD ($)
Cash and cash equivalents	$ 79,814
Property and equipment, net	20,533
In process Research & Development (IPRD)	7,800,000
Goodwill	2,458,233
Security deposit	12,785
Total asset acquired	10,371,365
Accrued expenses and other current liabilities	5,767
Deferred taxes liability	2,340,000
Notes Payable including convertible and discount on conversion	519,598
Total liabilities assumed	2,865,365
Net assets acquired	$ 7,506,000

ACQUISITION OF SAPPHIRE BIOTE_4

ACQUISITION OF SAPPHIRE BIOTECH INC (Details Narrative) - USD ($)	May 11, 2015	Sep. 30, 2020	Mar. 31, 2020	Mar. 17, 2020	Sep. 30, 2021	Dec. 31, 2020
Common stock shares issued					135,885,104	125,327,579
Common stock fair value					$ 13,589	$ 12,533
Liabilities					9,600,293	9,748,574
Total acquisition cost					2,609,100
Goodwill					2,458,233	$ 2,458,233
Acquisition ownership percentage	100.00%
Acquisition of common stock shares	5,826,706			6,000,000
Sapphire [Member]
Number of shares exchanged				54,000,000
Purchase Price				$ 7,918,233
Common stock shares issued			54,000,000
Common stock fair value		$ 7,506,000	$ 7,506,000
Liabilities		412,233	412,233
Total acquisition cost			$ 7,918,233
Common stock fair value based on closing pice		7,506,000
Goodwill					$ 2,458,233
Share exchanged				54,000,000
Acquisition ownership percentage				100.00%
Net liabilities assumed				$ 412,233
Acquisition of common stock shares				100,000,000
Aggregate purchase price		$ 7,918,233

ACQUISITION OF ASSET OF ADVANCE

ACQUISITION OF ASSET OF ADVANCED TEAR DIAGNOSTIC, LLC. (Details Narrative) - USD ($)	May 11, 2015	Jul. 29, 2021	Jul. 26, 2021	Mar. 17, 2020	Sep. 30, 2021
Acquisition of common stock shares	5,826,706			6,000,000
Purchase price for acquisition					$ 2,609,100
Tear Diagnostics LLC [Member]
Purchase price		$ (210,000)
Licenses fee			$ 4,270,000
Monthly payments		$ 30,000
Acquisition of common stock shares			7,000,000
Purchase price for acquisition					$ 4,520,000

GOING CONCERN (Details Narrativ

GOING CONCERN (Details Narrative) - USD ($)	9 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
GOING CONCERN (Details Narrative)
Working capital deficit	$ (1,094,813)
Accumulated deficit	(49,833,059)	$ (41,849,922)
Cash used in operating activities of continuing operations	1,689,200
Cash used in operating activities of discontinued operations	$ 4,633

SIGNIFICANT ACCOUNTING POLICI_4

SIGNIFICANT ACCOUNTING POLICIES SIGNIFICANT ACCOUNTING POLICIES (Details) - USD ($)	Sep. 30, 2021	Dec. 31, 2020
SIGNIFICANT ACCOUNTING POLICIES
Equipment	$ 154,809	$ 134,788
Less: accumulated depreciation	50,812	30,694
Property, Plant and Equipment, Net	$ 103,997	$ 104,094

SIGNIFICANT ACCOUNTING POLICI_5

SIGNIFICANT ACCOUNTING POLICIES (Details 1) - USD ($)	Sep. 30, 2021	Dec. 31, 2020
SIGNIFICANT ACCOUNTING POLICIES
Goodwill	$ 2,458,233	$ 2,458,233
Intellectual Property (IPRD)	7,800,000	7,800,000
Patents	250,000	0
Licenses	4,270,000	0
Finite-Lived Intangible Assets, Gross	14,778,233	10,258,233
Less: accumulated amortization and impairment	1,333,954	0
Intangible Assets, Net (Including Goodwill)	$ 13,444,279	$ 10,258,233

SIGNIFICANT ACCOUNTING POLICI_6

SIGNIFICANT ACCOUNTING POLICIES (Details 2)	Sep. 30, 2021USD ($)
SIGNIFICANT ACCOUNTING POLICIES
2021	$ 2,088,000
2022	2,990,000
2023	2,990,000
2024	$ 1,040,000

SIGNIFICANT ACCOUNTING POLICI_7

SIGNIFICANT ACCOUNTING POLICIES (Details Narrative) - USD ($)	1 Months Ended	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020
SIGNIFICANT ACCOUNTING POLICIES
Concentrations percentage, accounts receivable				100.00%		100.00%
Cash and cash equivalents		$ 0		$ 0		$ 0
Concentrations percentage, revenue	1.00%			100.00%
Inventory		20,127		$ 20,127		$ 0
Depreciation		6,935	$ 5,372	20,119	$ 10,497
Revenues from continuing operations		8,127	0	55,651	0
Revenues from discontinuing operations		0	0	0	7,990
Disposal Group, Including Discontinued Operation, Revenue		0	0	0	7,990
Income from Grants from Government		59,986	25,899	$ 279,981	25,899
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount				30,530,216		32,556,727
Research and Development Expense from continuing operation		67,263	109,139	$ 216,282	235,431
Research and Development Expense from discontinuing operation		$ 0	$ (400,417)	$ 0	$ 426,665

PREPAID EXPENSES (Details)

PREPAID EXPENSES (Details) - USD ($)	Sep. 30, 2021	Dec. 31, 2020
Prepaid expenses	$ 141,542	$ 255,923
Prepaid Insurance
Prepaid expenses	96,881	45,983
Prepaid Services
Prepaid expenses	$ 44,661	$ 209,940

PREPAID EXPENSES (Details Narra

PREPAID EXPENSES (Details Narrative) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
ORGANIZATION
Amortization of prepaid expenses	$ 80,384	$ 78,504	$ 296,542	$ 146,583

PROMISSORY NOTE (Details Narrat

PROMISSORY NOTE (Details Narrative) - USD ($)	Aug. 08, 2014	Dec. 31, 2019	Jan. 02, 2019	Sep. 25, 2018	Mar. 20, 2018	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Nov. 20, 2021	Dec. 31, 2020	May 31, 2014
Working Capital						$ (952,445)		$ (952,445)
Interest Expense						0	$ 0	0	$ 0
Accrued Liabilities, Current						1,445		1,445			$ 675
Share-based Payment Arrangement, Noncash Expense								953,076	$ 779,029
Clinical Trial Fee										$ 5,000
Series B Preferred Stock [Member]
Preferred Stock, Shares Outstanding											500,000
Debt Exchange Agreement [Member]
Accrued Liabilities, Current						358,315		358,315			$ 343,725
Tear Diagnostics LLC [Member]
Note payable						210,000		210,000
Note balance						180,000		180,000
Accrued interest						125		125
Can Chew Biotechnologies [Member] | Promissory Bote Agreement [Member]
Working Capital	$ 1,000,000
Debt Instrument, Interest Rate During Period	7.00%
Can Chew Biotechnologies [Member] | Debt Exchange Agreement [Member]
Debt Instrument, Interest Rate During Period		6.00%
Sapphire Biotech [Member] | Debt Exchange Agreement [Member]
Debt Instrument, Face Amount		$ 324,218
Sapphire Biotech [Member] | Debt Exchange Agreement 7 [Member]
Interest Expense		14,218
Loans Assumed		310,000
Sapphire Biotech [Member] | Debt Exchange Agreement 3 [Member]
Loans Assumed		$ 128,375
Chairman [Member]
Working Capital Advance												$ 5,000
Accounts Payable, Current						40,000		40,000			225,000
Chairman [Member] | Consulting Agreement [Member]
Consulting fees			$ 20,000
Mr Changoer [Member]
Accounts Payable, Current						20,000		20,000			60,000
Mr Changoer [Member] | Agreement [Member]
Shares Issued, Shares, Share-based Payment Arrangement, after Forfeiture					50,000
Shares Issued, Value, Share-based Payment Arrangement, after Forfeiture					$ 235,000
Director [Member]
Accounts Payable, Current						$ 0		$ 0			$ 25,000
Director [Member] | Compensation Agreement [Member]
Share-based Payment Arrangement, Noncash Expense				$ 20,000

RELATED PARTY TRANSACTIONS (Det

RELATED PARTY TRANSACTIONS (Details Narrative) - USD ($)	Jun. 07, 2021	May 04, 2020	May 24, 2020	Sep. 30, 2021	Sep. 30, 2020	Jun. 30, 2020	Sep. 30, 2021	Jun. 30, 2021	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020	Mar. 17, 2020
Accounts and Financing Receivable, after Allowance for Credit Loss											$ 102,567
Common stock to be issued			$ 90,000			$ 135,000
Loss on Extinguishment of Debt	$ 1,535,264			$ 0	$ 923,604		$ (1,535,264)	$ (1,535,264)	$ 1,535,264	$ 923,604
Accrued Liabilities, Current				$ 1,445			$ 1,445		$ 1,445		$ 675
Catlina Valencia [Member]
Accounts Payable, Related Parties, Current												$ 15,000
Dr Anastassov [Member] | Forbearance Agreement [Member]
Common stock to be issued		$ 135,000
Loss on Extinguishment of Debt		32,433
Dr Anastassov [Member] | Purchase Promissory Note [Member] | Forbearance Agreement [Member]
Accounts and Financing Receivable, after Allowance for Credit Loss		102,567
Debt Instrument, Face Amount		350,000
Due to Related Parties, Current		$ 100,000

DUE TO FIRST INSURANCE FUNDING

DUE TO FIRST INSURANCE FUNDING (Details Narrative) - USD ($)	9 Months Ended	12 Months Ended
	Sep. 30, 2021	Dec. 31, 2020	Jun. 25, 2021	Jun. 25, 2020
ACQUISITION OF SAPPHIRE BIOTECH INC (Details)
Insaurance renewal fee			$ 98,888	$ 93,357
Cash down payment			24,273	18,671
Premium paid			$ 1,797	$ 8,456
Total Outstanding amount	$ 65,880	$ 25,369

CONVERTIBLE NOTES PAYABLE Sched

CONVERTIBLE NOTES PAYABLE Schedule of Convertible Notes Payable Shareholder (Details) - USD ($)	9 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
Debt Instrument, Maturity Date	Nov. 1, 2026
Debt Instrument, Interest Rate, Stated Percentage	3.50%
Convertible notes payable due to shareholder
Debt Instrument, Face Amount	$ 4,000,000	$ 4,000,000
Accrued interest	264,037	158,648
Convertible note payable, net	$ 4,264,037	$ 4,158,648

CONVERTIBLE NOTES PAYABLE Sch_2

CONVERTIBLE NOTES PAYABLE Schedule of Convertible Note Payable of Related Party (Details) - USD ($)	Sep. 30, 2021	Dec. 31, 2020
Total	$ 1,992,402	$ 2,520,461
Less: unamortized debt discount/finance premium costs	(623,095)	(843,673)
Convertible Note Payable Net	1,369,307	1,676,788
Convertible note payable
Accrued interest	208,089	236,148
Convertible Note Payable 1 [Member]
Total	484,478	484,478
Convertible Note Payable 2 [Member]
Total	500,000	1,000,000
Convertible Note Payable 3 [Member]
Total	190,000	190,000
Convertible Note Payable 4 [Member]
Total	$ 609,835	$ 609,835

CONVERTIBLE NOTES PAYABLE (Deta

CONVERTIBLE NOTES PAYABLE (Details Narrative) - USD ($)	Jun. 07, 2021	May 11, 2015	Mar. 17, 2020	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Jun. 30, 2021	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020	Jun. 30, 2020	Dec. 31, 2019	May 02, 2019
Interest expenses				$ 35,000	$ 105,389			$ 35,000	$ 105,389
Loss on Extinguishment of Debt	$ 1,535,264			0	923,604	$ (1,535,264)	$ (1,535,264)	1,535,264	923,604
Acquisition of common stock shares		5,826,706	6,000,000
Debt Instrument, Convertible, Beneficial Conversion Feature			$ 190,000
Amortization of Debt Discount (Premium)				17,546	$ 22,313			220,578	$ 41,432
Debt Instrument, Unamortized Discount				623,095		623,095		623,095		$ 843,673
Convertible Note [Member]
Debt Instrument, Face Amount			$ 190,000
Secured Convertible Debt [Member]
Accrued interest				264,037		264,037		264,037		158,648
Convertible Debt				4,264,037		4,264,037		4,264,037		4,158,648
Secured Convertible Debt 1 [Member]
Accrued interest				84,800		84,800		84,800		71,942
Convertible Debt				569,278		569,278		569,278		556,420
Secured Convertible Debt 2 [Member]
Accrued interest				87,744		87,744		87,744		148,944
Convertible Debt				587,744		587,744		587,744		1,148,944
Secured Convertible Debt 3 [Member]
Accrued interest				9,991		9,991		9,991		5,716
Convertible Debt				199,991		199,991		199,991		195,716
Secured Convertible Debt 4 [Member]
Accrued interest				25,554		25,554		25,554		9,546
Convertible Debt				$ 635,389		$ 635,389		$ 635,389		$ 619,381
Sapphire Biotech [Member] | Debt Exchange Agreement [Member]
Debt Instrument, Face Amount												$ 324,218
Medical Marijuana Inc [Member] | Debt Exchange Agreement [Member]
Accrued interest													$ 60,278
Kannaway [Member]
Accounts Receivable, after Allowance for Credit Loss, Noncurrent											$ 75,074

STOCK INCENTIVE PLAN (Details N

STOCK INCENTIVE PLAN (Details Narrative) - USD ($)

Sep. 08, 2021

Aug. 02, 2021

Sep. 10, 2020

Sep. 04, 2020

May 13, 2020

Aug. 17, 2021

May 20, 2021

May 29, 2015

Sep. 30, 2021

Sep. 30, 2020

Sep. 30, 2021

Sep. 30, 2020

Dec. 31, 2020

Stock available for issuance

8,739,285

8,739,285

9,806,000

Share-based Payment Arrangement, Expense

$ 761,810

$ 414,839

$ 953,076

$ 235,000

2015 Stock Incentive Plan [Member]

Common stock issued under registration statement on Form S-8

10,000,000

Increase of issuance shares

20,000,000

Alim Seit-Nebi [Member]

Option granted purchase shares

1,000,000

Exercise price

$ 0.126

Stock option vesting description

One third of the options will vest six months from the date of grant, one third of the options will vest one year from the date of grant

Douglas Lake [Member]

Option granted purchase shares

2,000,000

Exercise price

$ 0.126

Stock option vesting description

One third of the options will vest six months from the date of grant, one third of the options will vest one year from the date of grant

Robert Cunningham [Member]

Option granted purchase shares

500,000

Exercise price

$ 0.126

Stock option vesting description

One third of the options vested immediately, one third of the options will vest six months from the date of grant, and the remaining one third of the options will vest twelve months from the date of grant

Jeft Busby [Member]

Option granted purchase shares

1,000,000

Stock option vesting description

25% of the Option shares will be vested upon the three anniversary of the vesting commencement day and 25% of the Option shares will be vested upon the four anniversaries of the vesting commencement day

Purchase price of stock option

$ 0.60

Joseph Tauber [Member]

Option granted purchase shares

1,000,000

Stock option vesting description

25% of the Option shares will be vested upon the one anniversary of the vesting commencement day, 25% of the Option shares will be vested upon the two anniversaries of the vesting commencement day, 25% of the Option shares will be vested upon the three anniversary of the vesting commencement day and 25% of the Option shares will be vested upon the four anniversaries of the vesting commencement day

Purchase price of stock option

$ 0.622

Laura M. Periman [Member]

Option granted purchase shares

100,000

Stock option vesting description

50% of the Option shares will be vested upon the one anniversary of the vesting commencement day and 50% of the Option shares will be vested upon the two anniversaries of the vesting commencement day

Purchase price of stock option

$ 0.64

Kelly K. Nichols [Member]

Option granted purchase shares

100,000

Stock option vesting description

50% of the Option shares will be vested upon the one anniversary of the vesting commencement day and 50% of the Option shares will be vested upon the two anniversaries of the vesting commencement day.

Purchase price of stock option

$ 0.62

Timothy R, Scott [Member]

Option granted purchase shares

500,000

Exercise price

$ 0.126

Stock option vesting description

one third of the options will vest six months from the date of grant, and the remaining one third of the options will vest twelve months from the date of grant

Maurico Bellora [Member]

Option granted purchase shares

500,000

Exercise price

$ 0.126

Stock option vesting description

one third of the options will vest six months from the date of grant, and the remaining one third of the options will vest twelve months from the date of grant

Noel C. Gillespie [Member]

Option granted purchase shares

500,000

Stock option vesting description

One third of the options vested immediately, one third of the options will vest one year from the date of grant, and the remaining one third of the options will vest two years from the date of grant

Purchase price of stock option

$ 0.61

Bijan Pedram [Member]

Option granted purchase shares

100,000

Stock option vesting description

25% of the Option shares will be vested upon the one anniversary of the vesting commencement day and the balance of the option shares will be vested of thirty-six (36) successive equal monthly in the first anniversary of the vesting commencement day.

Purchase price of stock option

$ 0.67

STOCKHOLDERS DEFICIT (Details N

STOCKHOLDERS DEFICIT (Details Narrative) - USD ($)	Oct. 13, 2021	Dec. 07, 2020	Aug. 12, 2020	Aug. 10, 2020	Aug. 06, 2020	Aug. 04, 2020	Jul. 10, 2020	Jun. 10, 2020	May 06, 2020	Oct. 19, 2021	Jul. 29, 2021	Jul. 24, 2021	Jul. 21, 2021	Mar. 31, 2021	Mar. 18, 2021	Jul. 22, 2020	Jun. 24, 2020	May 24, 2020	May 22, 2020	Apr. 21, 2020	Mar. 17, 2020	Feb. 26, 2020	Feb. 23, 2020	Jan. 23, 2020	Jan. 02, 2020	Feb. 20, 2019	Jun. 30, 2020	Mar. 31, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020	Aug. 18, 2016	Aug. 17, 2016
Preferred Stock, Shares Authorized																													5,000,000		5,000,000
Stock Issued During Period, Shares, Restricted Stock Award, Gross																			90,810			62,839							500,000
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																						$ 25,000							$ 332,500
Number of shares issued, shares																													175,000
Number of shares issued amount																											$ 548,000	$ 962,500	$ 52,500
Preferred Stock, Par or Stated Value Per Share																													$ 0.0001		$ 0.0001
Undesignated Preferred Stock																													4,000,000
Undesignated preferred shares outstanding																													0		0
Common Stock, Shares Authorized																													300,000,000		300,000,000
Common Stock, Shares, Outstanding																													135,885,104		125,327,579
Loss on extinguishment of debt																													$ 1,535,264	$ 923,604
Common stock to be issued																		$ 90,000									$ 135,000
Warrants issued														900,000
Stock Option, Exercise Price, Decrease														$ 0.75
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term														3 months
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period									18,570,356
Stock Issued During Period, Value, Restricted Stock Award, Forfeitures									$ 2,562,709
Conversion Convertible Note Payable								$ 51,414
Stock Issued For Prepaid Marketing Expenses, shares												359,524
Stock Issued For Prepaid Marketing Expenses, value												$ 302,000
Additional paid in capital																													50,009,591		$ 43,201,186
Cross Company [Member]
Proceeds from Related Party Debt													$ 609,835
Stock Purchase Agreements [Member]
Common stock to be issued														$ 434,000
Stock Issued During Period, Shares, New Issues														1,712,500
Warrant Stock Purchase Agreements [Member]
Common stock to be issued																													$ 402,500
Stock Issued During Period, Shares, New Issues																													1,234,113
Promissory Note [Member]
Debt Instrument, Face Amount																										$ 435,000
Conversion Of Convertible Note [Member]
Loss on extinguishment of debt																													$ 1,535,264
Convertible Preferred Stock Series C
Preferred Stock, Shares Authorized																													500,000		500,000		500,000
Preferred Stock, Par or Stated Value Per Share																													$ 0.0001		$ 0.0001
Advanced Tear Diagnostics, LLC [Member]
Number of shares issued, shares																													7,000,000
Number of shares issued amount																													$ 4,270,000
M J N A Investment Holdings L L C [Member]
Purchase Price																										$ 500,000
M J N A Investment Holdings L L C [Member] | Series C Convertible Preferred Stock
Preferred Stock, Shares Authorized																																500,000
Share exchange for cash																																$ 65,000
Third Party [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross	118,000			115,554																					250,000				2,647,464
Restricted Stock, Value, Shares Issued Net of Tax Withholdings	$ 70,800			$ 100,000																									$ 2,117,971
Accrued interest																													$ 582,707
Stock Issued for severence fees, shares					148,166
Stock Issued for severence fees, value					$ 120,000
Third Party [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross			414,419	122,000		141,243		200,000		175,000	122,000					65,359				1,176,470
Restricted Stock, Value, Shares Issued Net of Tax Withholdings			$ 76,690	$ 50,000		$ 50,000				$ 152,500	$ 50,000					$ 20,000					$ 100,000
Common stock to be issued								$ 23,630
Stock Issued for severence fees, shares		130,609
Stock Issued for severence fees, value		$ 75,000
Third Party [Member] | S 1 Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																													50,000
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																													$ 332,500
Actual proceeds																													228,812
Additional paid in capital																													$ 103,688
Third Parties [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																													1,114,351
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																									$ 50,000				$ 792,389
Third Parties 4 [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross															488,428
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																													$ 291,974
Third Partiess [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																								600,000
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																							$ 262,500
Third Partiess 1 [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																						62,839
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																						$ 25,000
Sapphire Stockholders [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																					54,000,000
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																					$ 7,506,000
Third Party 1 [Member]
Stock Issued for severence fees, shares					166,686
Stock Issued for severence fees, value					$ 135,000
Third Party 1 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross								2,173,913								130,719
Restricted Stock, Value, Shares Issued Net of Tax Withholdings							$ 40,000	$ 50,000
Third Party 2 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																163,398	625,000
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																$ 50,000	$ 100,000
Third Party 3 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross								185,185								326,797
Restricted Stock, Value, Shares Issued Net of Tax Withholdings							$ 100,000	$ 250,000
Third Party 4 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																816,993	370,370
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																$ 250,000	$ 50,000
Third Party 5 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross								714,285								65,359
Restricted Stock, Value, Shares Issued Net of Tax Withholdings								$ 100,000								$ 20,000
Third Party 6 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																	1,785,714
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																	$ 250,000
Third Party 8 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross							142,857
Restricted Stock, Value, Shares Issued Net of Tax Withholdings							$ 20,000
Third Party 9 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross							357,153
Restricted Stock, Value, Shares Issued Net of Tax Withholdings							$ 50,000
Third Party 10 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross							250,000
Restricted Stock, Value, Shares Issued Net of Tax Withholdings							$ 35,000
Third Party 11 [Member] | Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross							107,143
Restricted Stock, Value, Shares Issued Net of Tax Withholdings							$ 15,000
Third Party 7 [Member] | Stock Purchase Agreement [Member]
Common stock to be issued								$ 5,141,377
July and September 2021 [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																			190,810			62,839							1,415,554
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																						$ 25,000							$ 1,111,900
August and September 2021 [Member]
Common stock warrant purchase shares																													1,060,715
Proceeds from issuance of warrants																													$ 297,000
Exercise price																													$ 0.60
Warrants are exercisable period																													3 years
September 2021 [Member]
Stock Issued During Period, Shares, Restricted Stock Award, Gross																			90,810			62,839							129,724
Restricted Stock, Value, Shares Issued Net of Tax Withholdings																						$ 25,000							$ 262,400

STOCK OPTIONS AND WARRANTS (Det

STOCK OPTIONS AND WARRANTS (Details) - $ / shares	9 Months Ended	12 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
STOCK OPTIONS AND WARRANTS
Options outstanding, beginning balance	10,300,000	2,000,000
Weighted Average Exercise Price, beginning	$ 0.36	$ 0.75
Granted	2,960,715	8,300,000
Granted	$ 0.60	$ 0.27
Expired or canceled	(2,000,000)
Expired or canceled	$ 0.75
Options outstanding, Ending balance	11,260,715	10,300,000
Weighted Average Exercise Price, ending	$ 0.36	$ 0.36

STOCK OPTIONS AND WARRANTS (D_2

STOCK OPTIONS AND WARRANTS (Details 1) - $ / shares	9 Months Ended	12 Months Ended
	Sep. 30, 2021	Dec. 31, 2020	Jun. 30, 2021	Dec. 31, 2019
Weighted Average Exercise Price, beginning	$ 0.36	$ 0.36	$ 0.36	$ 0.75
Options outstanding, beginning balance	11,260,715	10,300,000	8,300,000	2,000,000
Common stock issued to employees and consultants under a stock option plan
Weighted Average Exercise Price, beginning	$ 0.36	$ 0.36
Options outstanding, beginning balance	10,300,000	11,260,715
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term	9 years 6 months	9 years 9 months 18 days
Number Exercisable	8,227,380	7,466,662
Weighted Average Exercise Price ($)	$ 0.36	$ 0.36

STOCK OPTIONS AND WARRANTS (D_3

STOCK OPTIONS AND WARRANTS (Details 2) - $ / shares	9 Months Ended	12 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
STOCK OPTIONS AND WARRANTS
Expected life (years)	10 years	10 years
Risk-free interest rate (%)	1.74%	0.61%
Expected volatility (%)	190.00%	230.00%
Dividend yield (%)	0.00%	0.00%
Weighted average fair value of shares at grant date	$ 1.74	$ 0.61

STOCK OPTIONS AND WARRANTS (D_4

STOCK OPTIONS AND WARRANTS (Details 3) - $ / shares	9 Months Ended	12 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
Options outstanding, beginning balance	10,300,000	2,000,000
Granted	2,960,715	8,300,000
Forfeited/Cancelled	2,000,000
Options outstanding, Ending balance	11,260,715	10,300,000
Weighted Average Exercise Price, beginning	$ 0.36	$ 0.75
Forfeited/Cancelled per share	0.75
Weighted Average Exercise Price, ending	$ 0.36	$ 0.36
Warrants
Options outstanding, beginning balance	0
Granted	2,850,000
Exercised	$ 0
Forfeited/Cancelled	0
Options outstanding, Ending balance	2,805,000	0
Weighted Average Exercise Price, beginning	$ 0
Granted per share	0.71
Exercised per share	0
Forfeited/Cancelled per share	0
Weighted Average Exercise Price, ending	$ 0.71	$ 0

STOCK OPTIONS AND WARRANTS (D_5

STOCK OPTIONS AND WARRANTS (Details Narrative) - USD ($)	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020
Expired or canceled			2,000,000
Stock-based compensation expense	$ 761,810	$ 0	$ 953,076	$ 779,029
John Huemoeller [Member]
Expired or canceled			2,000,000		2,000,000

DISCONTINUED OPERATIONS (Detail

DISCONTINUED OPERATIONS (Details)	Sep. 30, 2021USD ($)
DISCONTINUED OPERATIONS
Other current assets	$ 5,000
Total current assets	510,017
Intangible assets, net of amortization	47,375
Total asset	562,392
Notes payable	880,000
Accounts payable and accrued expenses	210,640
Due to Canchew	1,526,603
Stock retired	1,857
Loss on sale of assets	562,392
Gain on sale of liabilities	2,619,100
Net gain from sale of assets and liabilities	$ 2,056,708

DISCONTINUED OPERATIONS (Deta_2

DISCONTINUED OPERATIONS (Details 1) - USD ($)	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
DISCONTINUED OPERATIONS
Net sales	$ 0	$ 5,097
Total expenses	(4,633)	(1,935,278)
Gain from sale of asset and liability	0	2,046,708
Other loss (income)	0	(87,383)
(Loss) income from discontinued operations	(4,633)	29,144
Net (loss) income from discontinued operations	(4,633)	29,144
Adjustment of non-cash activities	0	(1,551,166)
Decrease in accounts receivable	0	315,843
Increase in inventory	0	(22,203)
Increase in accounts payable and accrued expenses	0	393,953
Net cash provided by (used in) operating activities	(4,633)	(834,429)
Net cash provided by (used in) investing activities	0	0
Net cash provided by (used in) financing activities	$ 0	$ (65,000)

DISCONTINUED OPERATIONS (Deta_3

DISCONTINUED OPERATIONS (Details Narrative) - USD ($)	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
DISCONTINUED OPERATIONS
Recognized Interest Expense	$ 0	$ 0
Purchase price for acquisition	$ 2,609,100

COMMITMENT AND CONTINGENCIES (D

COMMITMENT AND CONTINGENCIES (Details) - USD ($)	9 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
COMMITMENT AND CONTINGENCIES
Right-of-use assets	$ 90,630	$ 130,722
Lease liability obligations, current	58,540
Lease liability obligations, noncurrent	32,090
Total lease liability obligations	$ 90,630
Weighted-average remaining lease term	1 year 6 months 29 days
Weighted-average discount rate	6.00%

COMMITMENT AND CONTINGENCIES _2

COMMITMENT AND CONTINGENCIES (Details 1) - USD ($)	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
COMMITMENT AND CONTINGENCIES
Operating Lease, Expense	$ 43,122	$ 18,852
Short-term lease expense	11,545	15,313
Total lease expense	$ 54,667	$ 34,165

COMMITMENT AND CONTINGENCIES _3

COMMITMENT AND CONTINGENCIES (Details 2)	Sep. 30, 2021USD ($)
COMMITMENT AND CONTINGENCIES
Remainder of 2021	$ 14,562
2022	59,416
2023	20,000
Total minimum payments	93,978
Less: amount representing interest	(3,348)
Total	$ 90,630

COMMITMENT AND CONTINGENCIES _4

COMMITMENT AND CONTINGENCIES (Details Narrative) - USD ($)	Jan. 02, 2019	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2019
Salary	$ 10,000
Implicit interest rate				6.00%
Monthly base rent				$ 54,667	$ 34,165
Maintenance costs				$ 11,545
Terms of exclusivity agreement				On December 20, 2018 the Company signed Exclusivity Agreement on terms that include Exclusivity period of 90 days after the date on which this agreement is executed with Impression in exchange for 10,300,000 ordinary fully paid shares in Impression at the price of A$0.02 per share and exchange rate of $0.74 AUD/USD valued $150,000 which the Company recognized as a revenue in 4th quarter of 2018
Purchase price for acquisition				$ 2,609,100
Research and development expenses		$ 67,263	$ 109,139	216,282	235,431
John W. Huemoeller [Member]
Salary	10,000
Increase salary per month	$ 35,000
Common stock granted purchase shares	2,000,000
CFOMember
Increase salary per month	$ 3,000
LOI [Member]
Number of shares received						2,000,000
Sale and purchase aggregate amount						$ 1
Number of shares issued sold						7,375,000
Number of stock held						4,925,000
KISS [Member]
Annual royalty				50,000
Sponsored Research Agreement [Member]
Purchase price for acquisition				$ 150,468
License executed description				the License executed between Skysong Innovations and the Company, the SRA provides for a reduced overhead of 5% instead of the usual 67.7%
Overhead fee				$ 89,851
Deferred period				5 years
Interest rate				5.00%
Research and development expenses				$ 216,282
1st year [Member]
Monthly base rent				4,713
2nd year [Member]
Monthly base rent				4,854
3rd year [Member]
Monthly base rent				5,000
Small Business Innovation Research [Member]
Grant income received				279,981	$ 25,899
Small business awarded				$ 395,880

SUBSEQUENT EVENTS (Details Narr

SUBSEQUENT EVENTS (Details Narrative) - USD ($)	Oct. 13, 2021	Aug. 12, 2020	Aug. 10, 2020	Aug. 04, 2020	Jun. 10, 2020	Oct. 19, 2021	Sep. 29, 2021	Jul. 29, 2021	Jul. 22, 2020	May 22, 2020	Apr. 21, 2020	Mar. 17, 2020	Feb. 26, 2020	Jan. 02, 2020	Sep. 30, 2021
Restricted shares issued, shares										90,810			62,839		500,000
Value of restricted shares issued													$ 25,000		$ 332,500
Stock Purchase Agreement [Member]
Aggregate principal amount							$ 1,110,000
Original issue discount							100,000
Purchase price of note							$ 1,010,000
Third Party [Member]
Restricted shares issued, shares	118,000		115,554											250,000	2,647,464
Value of restricted shares issued	$ 70,800		$ 100,000												$ 2,117,971
Third Party [Member] | Stock Purchase Agreement [Member]
Restricted shares issued, shares		414,419	122,000	141,243	200,000	175,000		122,000	65,359		1,176,470
Value of restricted shares issued		$ 76,690	$ 50,000	$ 50,000		$ 152,500		$ 50,000	$ 20,000			$ 100,000