Exhibit 5.1
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![LOGO](https://capedge.com/proxy/8-K/0001193125-24-162003/g785247g0615112718150.jpg) | | Gibson, Dunn & Crutcher LLP One Embarcadero Center, Suite 2600 San Francisco, CA 94111-3715 Tel 415.393.8200 gibsondunn.com |
June 17, 2024
Ultragenyx Pharmaceutical Inc.
60 Leveroni Ct.
Novato, CA 94949
Re: | Ultragenyx Pharmaceutical Inc. Registration Statement on Form S-3 (File No. 333-277226) |
Ladies and Gentlemen:
We have examined the Registration Statement on Form S-3, File No. 333-277226 (the “Registration Statement”), of Ultragenyx Pharmaceutical Inc., a Delaware corporation (the “Company”), filed with the Securities and Exchange Commission (the “Commission”) pursuant to the Securities Act of 1933, as amended (the “Securities Act”), and the prospectus supplement thereto dated June 13, 2024 (the “Prospectus Supplement”), in connection with the offering by the Company of up to 8,782,051 shares of the Company’s common stock (the “Common Stock”), par value $0.001 per share (the “Shares”), and pre-funded warrants (the “Pre-Funded Warrants”) to purchase 1,538,501 shares of Common Stock (the “Warrant Shares”). The Shares and Pre-Funded Warrants are being sold pursuant to the Underwriting Agreement dated as of June 13, 2024 (the “Underwriting Agreement”) among the Company and the Underwriters named therein (the “Underwriters”).
In arriving at the opinion expressed below, we have examined originals, or copies certified or otherwise identified to our satisfaction as being true and complete copies of the originals, of specimen Common Stock certificate, the form of Pre-Funded Warrant and such other documents, corporate records, certificates of officers of the Company and of public officials and other instruments as we have deemed necessary or advisable to enable us to render the opinions set forth below. In our examination, we have assumed without independent investigation the genuineness of all signatures, the legal capacity and competency of all natural persons, the authenticity of all documents submitted to us as originals and the conformity to original documents of all documents submitted to us as copies.
Based upon the foregoing, and subject to the assumptions, exceptions, qualifications and limitations set forth herein, we are of the opinion that (i) the Shares have been duly authorized and, when issued and delivered pursuant to the Underwriting Agreement against payment of the consideration set forth therein, will be validly issued, fully paid and non-assessable, (ii) provided that the Pre-Funded Warrants have been duly executed and
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