Exhibit 32.1
CERTIFICATION PURSUANT TO
18 U.S.C. SECTION 1350,
AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
In connection with the Quarterly Report on Form 10-Q of Alkermes plc (the “Company”) for the period ended June 30, 2024 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), we, Richard F. Pops, Chairman and Chief Executive Officer of the Company, and Blair C. Jackson, Executive Vice President, Chief Operating Officer and Interim Principal Financial Officer of the Company, certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to our knowledge:
| Date: July 24, 2024 |
| /s/ Richard F. Pops |
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| Richard F. Pops | |
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| Chairman and Chief Executive Officer | |
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| (Principal Executive Officer) | |
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| Date: July 24, 2024 |
| /s/ Blair C. Jackson |
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| Blair C. Jackson | |
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| Executive Vice President, Chief Operating Officer | |
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| (Interim Principal Financial Officer) | |
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