(1) | Consists of (i) 176,741 shares of the Registrant’s common stock that are held by the Muneer A. Satter Revocable Trust for which Muneer A. Satter serves as trustee and, in such capacity, has sole voting and dispositive power over all such shares, (ii) 417,731 shares that are held by various other trusts and other entities for which Muneer A. Satter serves as trustee, investment advisor or manager and, in such capacity, has sole voting and dispositive power over all such shares, (iii) 845,224 shares that are held by Satter medical Technology Partners, L.P. for which Muneer A. Satter has sole voting and dispositive power over all such shares, and (iv) 1,560,304 shares of the Registrant’s common stock held by Alerce Medical Technology Partners, L.P. for which Muneer A. Satter has sole voting and dispositive power over all such shares. Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), the shares of the Registrant’s common stock being registered hereunder include such indeterminate number of shares of common stock as may be issuable with respect to the shares of common stock being registered hereunder as a result of any stock dividend, stock split, recapitalization or similar transaction. |