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Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
Phio Pharmaceuticals Corp.
Marlborough, Massachusetts
We hereby consent to the incorporation by reference in the Registration Statements on Forms S-8 (No. 333-251670, 333-189521, 33-215871, 333-227013 and 333-230547) and Form S-3 (Nos. 333-224031 and 333-252588) of Phio Pharmaceuticals Corp. of our report dated March 25, 2021, relating to the consolidated financial statements, which appear in this Annual Report on Form 10-K.
/s/ BDO USA, LLP
Boston, Massachusetts
March 25, 2021