EXHIBIT 32.1
CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350
AS ADOPTED PURSUANT TO SECTION 906
OF THE SARBANES-OXLEY ACT OF 2002
Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, John A. Crum, Chairman and Chief Executive Officer of Midstates Petroleum Company, Inc. (the “ Company” ), and Thomas L. Mitchell, Executive Vice President and Chief Financial Officer of the Company, certify that, to their knowledge:
(1) the Quarterly Report on Form 10-Q of the Company for the period ending March 31, 2012, as filed with the Securities and Exchange Commission on the date hereof (the “ Report ”), fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934, as amended; and
(2) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.
| MIDSTATES PETROLEUM COMPANY, INC. |
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Dated: June 1, 2012 | /s/ John A. Crum |
| John A. Crum |
| Chief Executive Officer and President |
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Dated: June 1, 2012 | /s/ Thomas L. Mitchell |
| Thomas L. Mitchell |
| Executive Vice President and Chief Financial Officer |
