| Cover | Oct. 21, 2024 |
| Cover [Abstract] | |
| Document Type | S-3 |
| Amendment Flag | false |
| Entity Registrant Name | XENETIC BIOSCIENCES, INC. |
| Entity Central Index Key | 0001534525 |
| Entity Tax Identification Number | 45-2952962 |
| Entity Incorporation, State or Country Code | NV |
| Entity Address, Address Line One | 945 Concord Street |
| Entity Address, City or Town | Framingham |
| Entity Address, State or Province | MA |
| Entity Address, Postal Zip Code | 01701 |
| City Area Code | 781 |
| Local Phone Number | 778-7720 |
| Entity Filer Category | Non-accelerated Filer |
| Entity Small Business | true |
| Entity Emerging Growth Company | false |
| Document Creation Date | Oct. 21, 2024 |
