Sabby Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
9 METERS BIOPHARMA INC	COM	654405109	661	564,527	SH		DFND	1	0	564,527	0
9 METERS BIOPHARMA INC	COM	654405959	3,065	26,197	SH	Put	DFND	1	0	26,197	0
ACTINIUM PHARMACEUTICALS INC	COM	00507W956	76	100	SH	Put	DFND	1	0	100	0
ACUTUS MEDICAL INC	COM	005111109	1,772	132,522	SH		DFND	1	0	132,522	0
ADAMIS PHARMACEUTICALS CORP	COM	00547W958	285	3,034	SH	Put	DFND	1	0	3,034	0
ADITX THERAPEUTICS INC	COM	007025109	424	166,363	SH		DFND	1	0	166,363	0
ADITX THERAPEUTICS INC	COM	007025959	1,383	5,423	SH	Put	DFND	1	0	5,423	0
AETERNA ZENTARIS INC	COM	007975902	53	462	SH	Call	DFND	1	0	462	0
AETERNA ZENTARIS INC	COM	007975952	227	1,994	SH	Put	DFND	1	0	1,994	0
AETERNA ZENTARIS INC	COM	007975402	682	598,442	SH		DFND	1	0	598,442	0
AGRIFY CORP	COM	00853E107	266	21,342	SH		DFND	1	0	21,342	0
AMARIN CORP PLC	ADR	023111956	200	322	SH	Put	DFND	1	0	322	0
AMARIN CORP PLC	ADR	023111206	1,050	169,136	SH		DFND	1	0	169,136	0
AMARIN CORP PLC	ADR	023111906	3,436	5,533	SH	Call	DFND	1	0	5,533	0
AMPLITECH GROUP INC	*W	03211Q119	1,500	342,425	SH		DFND	1	0	342,425	0
APPLIED GENETIC TECHNOLOGIES	COM	03820J950	1,914	3,775	SH	Put	DFND	1	0	3,775	0
ARCADIA BIOSCIENCES INC	COM	039014204	185	67,136	SH		DFND	1	0	67,136	0
ARCADIA BIOSCIENCES INC	COM	039014954	1,052	3,820	SH	Put	DFND	1	0	3,820	0
ARK	ETF	00214Q954	1,367	114	SH	Put	DFND	1	0	114	0
ASENSUS SURGICAL INC	COM	04367G903	2,131	6,556	SH	Call	DFND	1	0	6,556	0
ASENSUS SURGICAL INC	COM	04367G953	2,262	6,959	SH	Put	DFND	1	0	6,959	0
ASENSUS SURGICAL INC	COM	04367G103	7,478	2,301,061	SH		DFND	1	0	2,301,061	0
ASLAN PHARMACEUTICALS	ADS	04522R101	2,738	817,165	SH		DFND	1	0	817,165	0
ATOSSA THERAPEUTICS INC	COM	04962H506	511	242,237	SH		DFND	1	0	242,237	0
ATOSSA THERAPEUTICS INC	COM	04962H956	2,674	12,673	SH	Put	DFND	1	0	12,673	0
AURINIA PHARMACEUTICALS	COM	05156V902	609	469	SH	Call	DFND	1	0	469	0
AURINIA PHARMACEUTICALS	COM	05156V102	1,112	85,625	SH		DFND	1	0	85,625	0
AUTOLUS THERAPEUTICS LTD	ADS	05280R100	3,010	525,230	SH		DFND	1	0	525,230	0
AVEO PHARMACEUTICALS INC	COM	053588307	79	10,815	SH		DFND	1	0	10,815	0
AVEO PHARMACEUTICALS INC	COM	053588957	454	620	SH	Put	DFND	1	0	620	0
BARCLAYS BANK PLC	ETF	06746P621	5,985	525,000	SH		DFND	1	0	525,000	0
BARCLAYS BANK PLC	ETF	06746P901	16,343	14,336	SH	Call	DFND	1	0	14,336	0
BIO PATH HLDGS INC	COM	09057N300	505	71,920	SH		DFND	1	0	71,920	0
BIOCEPT INC	COM	09072V501	313	61,464	SH		DFND	1	0	61,464	0
BIOCEPT INC	COM	09072V951	528	1,037	SH	Put	DFND	1	0	1,037	0
BIOGEN INC	COM	09062X953	2,798	100	SH	Put	DFND	1	0	100	0
BIOGEN INC	COM	09062X903	42,466	1,518	SH	Call	DFND	1	0	1,518	0
BIO-KEY INTL INC	COM	09060C408	117	33,487	SH		DFND	1	0	33,487	0
BIO-KEY INTL INC	COM	09060C958	547	1,566	SH	Put	DFND	1	0	1,566	0
BIOPHYTIS SA	ADS	09076G104	1,182	92,345	SH		DFND	1	0	92,345	0
BRAINSTORM CELL	COM	10501E201	523	136,610	SH		DFND	1	0	136,610	0
BRAINSTORM CELL	COM	10501E951	1,694	4,424	SH	Put	DFND	1	0	4,424	0
BRIACELL THERAPEUTICS	COM	10778Y302	618	160,182	SH		DFND	1	0	160,182	0
BUTTERFLY NETWORK INC	COM	124155102	556	33,047	SH		DFND	1	0	33,047	0
BUTTERFLY NETWORK INC	COM	124155902	668	397	SH	Call	DFND	1	0	397	0
CALADRIUS BIOSCIENCES INC	COM	128058203	936	484,970	SH		DFND	1	0	484,970	0
CALADRIUS BIOSCIENCES INC	COM	128058953	2,307	11,954	SH	Put	DFND	1	0	11,954	0
CARDIFF ONCOLOGY INC	COM	14147L958	156	169	SH	Put	DFND	1	0	169	0
CARDIFF ONCOLOGY INC	COM	14147L908	255	275	SH	Call	DFND	1	0	275	0
CBAK ENERGY TECHNOLOGY	COM	14986C952	5,932	11,632	SH	Put	DFND	1	0	11,632	0
CELLECTAR BIOSCIENCES INC	COM	15117F500	626	389,061	SH		DFND	1	0	389,061	0
CEL-SCI CORP	COM	150837957	2,202	1,448	SH	Put	DFND	1	0	1,448	0
CEL-SCI CORP	COM	150837907	2,677	1,760	SH	Call	DFND	1	0	1,760	0
CHINA JO JO DRUGSTORES INC	COM	16949A206	28	25,000	SH		DFND	1	0	25,000	0
CITIUS PHARMACEUTICALS INC	COM	17322U207	559	314,000	SH		DFND	1	0	314,000	0
CLEVELAND BIOLABS INC	COM	185860202	2,514	478,941	SH		DFND	1	0	478,941	0
COLLPLANT BIOTECHNOLOGIES LTD	ADS	19516R107	229	17,045	SH		DFND	1	0	17,045	0
CONTRAFECT CORP	COM	212326300	798	166,175	SH		DFND	1	0	166,175	0
CURIS INC	COM	231269900	912	985	SH	Call	DFND	1	0	985	0
DAXOR CORP	COM	239467103	1,437	118,736	SH		DFND	1	0	118,736	0
DIGINEX LTD	SHS	Y2074E959	649	592	SH	Put	DFND	1	0	592	0
DIGITAL ALLY INC	COM	25382P908	50	309	SH	Call	DFND	1	0	309	0
DIGITAL ALLY INC	COM	25382P208	1,129	692,350	SH		DFND	1	0	692,350	0
DIGITAL ALLY INC	COM	25382P958	1,666	10,220	SH	Put	DFND	1	0	10,220	0
EKSO BIONICS HLDGS INC	COM	282644301	2,612	423,360	SH		DFND	1	0	423,360	0
EXELA TECHNOLOGIES	COM	30162V409	1,635	750,000	SH		DFND	1	0	750,000	0
HEPION PHARMACEUTICALS INC	COM	426897954	254	1,382	SH	Put	DFND	1	0	1,382	0
HEPION PHARMACEUTICALS INC	COM	426897104	564	306,338	SH		DFND	1	0	306,338	0
HUMANCO ACQUISITION CORP	*W	44487N117	183	141,136	SH		DFND	1	0	141,136	0
HUMANCO ACQUISITION CORP	UNIT	44487N208	717	67,974	SH		DFND	1	0	67,974	0
HUMANCO ACQUISITION CORP	COM	44487N109	3,345	336,211	SH		DFND	1	0	336,211	0
INFINITY PHARMACEUTICALS INC	COM	45665G903	219	679	SH	Call	DFND	1	0	679	0
INFINITY PHARMACEUTICALS INC	COM	45665G303	1,712	530,000	SH		DFND	1	0	530,000	0
INTEC PHARMA LTD	SHS	M53644148	164	37,501	SH		DFND	1	0	37,501	0
IONIS PHARMACEUTICALS	COM	462222900	1,924	428	SH	Call	DFND	1	0	428	0
IONIS PHARMACEUTICALS	COM	462222100	2,459	54,688	SH		DFND	1	0	54,688	0
IONIS PHARMACEUTICALS	COM	462222950	3,732	830	SH	Put	DFND	1	0	830	0
ISHARES RUSSELL 2000	ETF	464287655	524	2,372	SH		DFND	1	0	2,372	0
ISHARES RUSSELL 2000	ETF	464287955	46,486	2,104	SH	Put	DFND	1	0	2,104	0
IT TECH PACKAGING INC	COM	46527C950	177	2,684	SH	Put	DFND	1	0	2,684	0
KANDI TECHNOLOGIES GROUP INC	COM	483709951	6,711	10,737	SH	Put	DFND	1	0	10,737	0
KEMPHARM INC	COM	488445906	3,858	4,193	SH	Call	DFND	1	0	4,193	0
KEMPHARM INC	COM	488445956	4,621	5,023	SH	Put	DFND	1	0	5,023	0
LEXARIA BIOSCIENCE CORP	*W	52886N117	695	291,000	SH		DFND	1	0	291,000	0
LIXTE BIOTECHNOLOGY HLDGS INC	COM	539319202	262	79,735	SH		DFND	1	0	79,735	0
LIXTE BIOTECHNOLOGY HLDGS INC	*W	539319111	128	157,374	SH		DFND	1	0	157,374	0
MACROGENICS INC	COM	556099959	580	182	SH	Put	DFND	1	0	182	0
MACROGENICS INC	COM	556099909	917	288	SH	Call	DFND	1	0	288	0
MEATECH 3D LTD	ADS	583435102	501	53,695	SH		DFND	1	0	53,695	0
MIRATI THERAPEUTICS INC	COM	60468T105	1,456	8,500	SH		DFND	1	0	8,500	0
MIRATI THERAPEUTICS INC	COM	60468T905	2,484	145	SH	Call	DFND	1	0	145	0
MMTEC INC	SHS	G6181K106	3,458	1,350,870	SH		DFND	1	0	1,350,870	0
MOGO INC	COM	60800C109	2,260	265,828	SH		DFND	1	0	265,828	0
MOGO INC	COM	60800C959	5,357	6,302	SH	Put	DFND	1	0	6,302	0
NABRIVA THERAPEUTICS PLC	SHS	G63637953	77	463	SH	Put	DFND	1	0	463	0
NABRIVA THERAPEUTICS PLC	SHS	G63637113	272	164,007	SH		DFND	1	0	164,007	0
NEMAURA MEDICAL INC	COM	640442958	383	501	SH	Put	DFND	1	0	501	0
NEWAGE INC	COM	650194103	6,763	2,364,694	SH		DFND	1	0	2,364,694	0
NUZEE INC	COM	67073S208	3,368	965,139	SH		DFND	1	0	965,139	0
OCEAN POWER TECHNOLOGIES INC	COM	674870956	1,375	4,153	SH	Put	DFND	1	0	4,153	0
OCULAR THERAPEUTIX INC	COM	67576A100	152	9,250	SH		DFND	1	0	9,250	0
OCULAR THERAPEUTIX INC	COM	67576A900	1,585	966	SH	Call	DFND	1	0	966	0
OCULAR THERAPEUTIX INC	COM	67576A950	2,018	1,230	SH	Put	DFND	1	0	1,230	0
ODONATE THERAPEUTICS INC	COM	676079106	2,171	634,728	SH		DFND	1	0	634,728	0
ORAMED PHARMACEUTICALS INC	COM	68403P953	1,713	1,686	SH	Put	DFND	1	0	1,686	0
PAINREFORM LTD	SHS	M77798102	1,459	330,000	SH		DFND	1	0	330,000	0
PENN NATIONAL GAMING INC	COM	707569109	4,235	40,399	SH		DFND	1	0	40,399	0
PENN NATIONAL GAMING INC	COM	707569959	7,664	731	SH	Put	DFND	1	0	731	0
PHASEBIO PHARMACEUTICALS INC	COM	717224109	52	15,000	SH		DFND	1	0	15,000	0
PHIO PHARMACEUTICALS INC	COM	71880W303	62	23,007	SH		DFND	1	0	23,007	0
PHIO PHARMACEUTICALS INC	COM	71880W953	427	1,591	SH	Put	DFND	1	0	1,591	0
PLURISTEM THERAPEUTICS INC	COM	72940R300	242	50,822	SH		DFND	1	0	50,822	0
PLURISTEM THERAPEUTICS INC	COM	72940R950	830	1,739	SH	Put	DFND	1	0	1,739	0
POLARITYTE INC	COM	731094958	150	1,355	SH	Put	DFND	1	0	1,355	0
POLARITYTE INC	COM	731094108	234	210,562	SH		DFND	1	0	210,562	0
PURPLE BIOTECH LTD	ADS	74638P109	78	18,847	SH		DFND	1	0	18,847	0
PURPLE BIOTECH LTD	ADS	74638P959	805	1,948	SH	Put	DFND	1	0	1,948	0
REDHILL BIOPHARMA LTD	ADS	757468103	4,621	631,287	SH		DFND	1	0	631,287	0
REVIVA PHARMACEURICALS HLDGS INC	COM	76152G100	2,402	418,437	SH		DFND	1	0	418,437	0
REVIVA PHARMACEURICALS HLDGS INC	*W	76152G118	161	350,000	SH		DFND	1	0	350,000	0
REWALK ROBOTICS LTD	SHS	M8216Q950	835	3,449	SH	Put	DFND	1	0	3,449	0
REWALK ROBOTICS LTD	SHS	M8216Q200	3,126	1,291,893	SH		DFND	1	0	1,291,893	0
RIOT BLOCKCHAIN INC	COM	767292105	959	18,000	SH		DFND	1	0	18,000	0
RIOT BLOCKCHAIN INC	COM	767292955	4,794	900	SH	Put	DFND	1	0	900	0
SAGE THERAPEUTICS INC	COM	78667J958	1,243	166	SH	Put	DFND	1	0	166	0
SALARIUS PHARMACEUTICALS INC	COM	79400X107	395	266,955	SH		DFND	1	0	266,955	0
SEANERGY MARITIME HLDGS CORP	SHS	Y73760194	2,114	1,994,783	SH		DFND	1	0	1,994,783	0
SECOND SIGHT MEDICAL PRODS INC	COM	81362J209	7,608	922,193	SH		DFND	1	0	922,193	0
SORRENTO THERAPEUTICS INC	COM	83587F202	8,807	1,064,933	SH		DFND	1	0	1,064,933	0
SORRENTO THERAPEUTICS INC	COM	83587F952	15,139	18,306	SH	Put	DFND	1	0	18,306	0
SPDR GOLD TRUST	SHS	78463V907	15,452	966	SH	Call	DFND	1	0	966	0
SPDR S&P 500 ETF TR	ETF	78462F953	33,054	834	SH	Put	DFND	1	0	834	0
SPDR SERIES TRUST	ETF	78464A870	1,185	8,735	SH		DFND	1	0	8,735	0
SPDR SERIES TRUST	ETF	78464A950	33,221	2,449	SH	Put	DFND	1	0	2,449	0
SPI ENERGY CO LTD	SHS	G8651P110	989	131,898	SH		DFND	1	0	131,898	0
SPI ENERGY CO LTD	SHS	G8651P950	70,355	5,568	SH	Put	DFND	1	0	5,568	0
STEALTH BIOTHERAPEUTICS CORP	ADS	85789A105	473	301,575	SH		DFND	1	0	301,575	0
TANZANIAN GOLD CORP	COM	87601A957	89	1,515	SH	Put	DFND	1	0	1,515	0
THE9 LTD	ADS	88337K302	259	8,293	SH		DFND	1	0	8,293	0
THE9 LTD	ADS	88337K952	487	156	SH	Put	DFND	1	0	156	0
THE9 LTD	ADS	88337K902	524	168	SH	Call	DFND	1	0	168	0
THERAPEUTICSMD INC	COM	88338N107	1,072	800,000	SH		DFND	1	0	800,000	0
TITAN PHARMACEUTICALS INC	COM	888314956	376	1,263	SH	Put	DFND	1	0	1,263	0
TRICIDA INC	COM	89610F101	1,877	354,755	SH		DFND	1	0	354,755	0
TRILLIUM THERAPEUTICS INC	COM	89620X956	625	582	SH	Put	DFND	1	0	582	0
TRILLIUM THERAPEUTICS INC	COM	89620X906	694	646	SH	Call	DFND	1	0	646	0
TRILLIUM THERAPEUTICS INC	COM	89620X506	2,143	199,569	SH		DFND	1	0	199,569	0
UCOMMUNE INTL LTD	COM	G9449A100	386	128,564	SH		DFND	1	0	128,564	0
VASCULAR BIOGENICS LTD	COM	M96883959	165	825	SH	Put	DFND	1	0	825	0
VAXCYTE INC	COM	92243G108	3,535	178,992	SH		DFND	1	0	178,992	0
VINCERX PHARMA INC	COM	92731L106	1,601	82,948	SH		DFND	1	0	82,948	0
VIRPAX PHARMACEUTICALS INC	COM	928251107	942	200,000	SH		DFND	1	0	200,000	0
VIRTRA INC	COM	92827K301	3,451	561,088	SH		DFND	1	0	561,088	0
WIMI HOLOGRAM CLOUD INC	ADS	97264L950	1,213	1,838	SH	Put	DFND	1	0	1,838	0
WIMI HOLOGRAM CLOUD INC	ADS	97264L100	6,473	980,786	SH		DFND	1	0	980,786	0
XPRESSPA GROUP INC	COM	98420U953	2,386	12,967	SH	Put	DFND	1	0	12,967	0