Stockholders Equity Note Disclosure [Text Block] | (8) Stockholders’ Equity (a) Issuance of Common Stock On April 29, 2015, the Company sold 5,347,500 32.4 2.3 (b) Share-Based Payments The Company recognizes stock-based compensation expense for grants of stock option awards, restricted stock units and restricted stock under the Company’s Incentive Plan to employees and nonemployee members of the Company’s board of directors based on the grant-date fair value of those awards. The grant-date fair value of an award is generally recognized as compensation expense over the award’s requisite service period. In addition, the Company grants performance-based stock option awards and restricted stock grants, which vest based upon the Company satisfying certain performance conditions. Potential compensation cost, measured on the grant date, related to these performance options will be recognized only if, and when, the Company estimates that these options will vest, which is based on whether the Company considers the options’ performance conditions to be probable of attainment. The Company’s estimates of the number of performance-based options that will vest will be revised, if necessary, in subsequent periods. In addition, the Company grants stock options to nonemployee consultants from time to time in exchange for services performed for the Company. Equity instruments granted to nonemployees are subject to periodic measurement revaluation over their vesting terms. During November 2014, the Company modified 149,498 166,000 366,126 836,000 907,336 2.81 422,000 The Company uses the Black-Scholes model to compute the estimated fair value of stock option awards. Using this model, fair value is calculated based on assumptions with respect to (i) expected volatility of the Company’s common stock price, (ii) the periods of time over which employees and members of the board of directors are expected to hold their options prior to exercise (expected term), (iii) expected dividend yield on the Common Stock, and (iv) risk-free interest rates. Stock-based compensation expense also includes an estimate, which is made at the time of grant, of the number of awards that are expected to be forfeited. This estimate is revised, if necessary, in subsequent periods if actual forfeitures differ from those estimates. 209,000 169,000 388,000 1.2 Three Months Ended Six Months Ended 2015 2014 2015 2014 Research and development $ 40,582 $ 55,249 $ 107,544 $ 270,664 General and administrative 168,155 113,491 280,235 943,462 $ 208,737 $ 168,740 $ 387,779 $ 1,214,126 The Company issued 188,500 6,000 188,500 37,500 Key assumptions used in the determination of the fair value of stock options granted are as follows: Expected Term Share-Based Payment, Risk-Free Interest Rate Expected Dividend Expected Volatility 2015 2014 Expected term 5.70 years 6.04 years Risk-free interest rate 1.66 % 1.93 % Expected dividend yield Expected volatility 80.95 % 73.09 % FASB ASC 718, Stock Compensation As of June 30, 2015, there was $ 2.2 2.02 5.06 5.20 (c) Stock Option Plan In April 2014, the board of directors adopted the 2014 Stock and Incentive Plan ("2014 Plan") subject to shareholder approval which was received in June 2014. The 2014 Plan provides for the granting of nonqualified and incentive stock options, stock appreciation rights, restricted stock units, restricted stock and dividend equivalents. An aggregate of 1,000,000 271,906 1,271,906 832,132 Outstanding stock options Number of Weighted average Balance at December 31, 2014 1,528,737 $ 4.20 Options granted 188,500 7.43 Options exercised (55,858) 2.81 Options forfeited - - Options cancelled (556) 18.34 Balance at June 30, 2015 1,660,823 4.61 Options exercisable at June 30, 2015 1,130,513 3.21 Options outstanding Options exercisable Number Weighted Weighted Aggregate intrinsic Number Weighted Weighted Aggregate 1,660,823 6.58 $ 4.61 $ 6,600,341 1,130,513 5.32 $ 3.21 $ 6,068,782 The intrinsic value for stock options is defined as the difference between the current market value and the exercise price. The total intrinsic value of 55,858 230,000 20,205 87,000 (d) Restricted Common Stock In 2010, the Company issued 112,720 In September 2013, the Company issued 12,000 Additionally, restricted shares issued to two members of the board of directors were further modified upon their retirement on January 6, 2014 to fully vest unvested restricted shares. Compensation expense was recorded as a result of the modifications (see note 8(b)). The grant date fair value of these shares when issued was $ 5.75 The Company includes unvested restricted stock in outstanding shares for financial reporting purposes when the awards vest. Number of Balance at December 31, 2014 7,000 Granted - Vested (2,000) Cancelled - Balance at June 30, 2015 5,000 (e) Restricted Stock Units On December 10, 2013, the Company issued 15,000 (f) Warrants For charitable purposes, on December 23, 2003, the Company granted warrants to a local university for 20,467 12.21 December 31, 2015 |