Stockholders Equity Note Disclosure [Text Block] | (8) Stockholders’ Equity (a) Issuance of Common Stock On April 29, 2015, the Company sold 5,347,500 32.4 2.3 (b) Share-Based Payments The Company recognizes stock-based compensation expense for grants of stock option awards, restricted stock units and restricted stock under the Company’s Incentive Plan to employees and nonemployee members of the Company’s board of directors based on the grant-date fair value of those awards. The grant-date fair value of an award is generally recognized as compensation expense over the award’s requisite service period. In addition, the Company grants performance-based stock option awards and restricted stock grants, which vest based upon the Company satisfying certain performance conditions. Potential compensation cost, measured on the grant date, related to these performance options will be recognized only if, and when, the Company estimates that these options will vest, which is based on whether the Company considers the options’ performance conditions to be probable of attainment. The Company’s estimates of the number of performance-based options that will vest will be revised, if necessary, in subsequent periods. In addition, the Company grants stock options to nonemployee consultants from time to time in exchange for services performed for the Company. Equity instruments granted to nonemployees are subject to periodic measurement revaluation over their vesting terms. During November 2014, the Company modified 149,498 166,000 366,126 836,000 907,336 2.81 422,000 The Company uses the Black-Scholes model to compute the estimated fair value of stock option awards. Using this model, fair value is calculated based on assumptions with respect to (i) expected volatility of the Company’s common stock price, (ii) the periods of time over which employees and members of the board of directors are expected to hold their options prior to exercise (expected term), (iii) expected dividend yield on the Common Stock, and (iv) risk-free interest rates. Stock-based compensation expense also includes an estimate, which is made at the time of grant, of the number of awards that are expected to be forfeited. This estimate is revised, if necessary, in subsequent periods if actual forfeitures differ from those estimates. 354,000 240,000 742,000 1.5 Three Months Ended September 30, Nine Months Ended September 30, 2015 2014 2015 2014 Research and development $ 73,417 $ 89,730 $ 180,960 $ 360,394 General and administrative 280,646 150,041 560,882 1,093,503 $ 354,063 $ 239,771 $ 741,842 $ 1,453,897 The Company issued 83,000 294,189 271,500 331,689 Key assumptions used in the determination of the fair value of stock options granted are as follows: Expected Term : The expected term represents the period that the stock-based awards are expected to be outstanding. Due to limited historical experience of similar awards, the expected term was estimated using the simplified method in accordance with the provisions of Staff Accounting Bulletin (“SAB”) No. 107, Share-Based Payment, Risk-Free Interest Rate : The risk-free interest rate used was based on the implied yield currently available on U.S. Treasury issues with an equivalent remaining term. Expected Dividend : The expected dividend assumption is based on management’s current expectation about the Company’s anticipated dividend policy. The Company does not anticipate declaring dividends in the foreseeable future. Expected Volatility : Since the Company does not have sufficient trading history, the volatility factor was based on a combination of the Company's volatility since being listed on the NASDAQ Capital Market and the average of eleven similar public companies. When selecting similar companies, the Company considered the industry, stage of life cycle, size, and financial leverage. 2015 2014 Expected term 5.75 years 5.87 years Risk-free interest rate 1.63 % 1.75 % Expected dividend yield Expected volatility 81.20 % 76.17 % FASB ASC 718, Stock Compensation As of September 30, 2015, there was $ 2.6 2.12 6.32 5.48 (c) Stock Option Plan In April 2014, the board of directors adopted the 2014 Stock and Incentive Plan ("2014 Plan") subject to shareholder approval which was received in June 2014. The 2014 Plan provides for the granting of nonqualified and incentive stock options, stock appreciation rights, restricted stock units, restricted stock and dividend equivalents. An aggregate of 1,000,000 271,906 1,271,906 749,132 Outstanding stock options Number of shares Weighted average exercise price Balance at December 31, 2014 1,528,737 $ 4.20 Options granted 271,500 9.21 Options exercised (98,574) 2.81 Options forfeited - - Options cancelled (556) 18.34 Balance at September 30, 2015 1,701,107 5.07 Options exercisable at September 30, 2015 1,198,594 3.64 The following table summarizes information about stock options outstanding and exercisable at September 30, 2015: Options outstanding Options exercisable Number Weighted average remaining Weighted average remaining outstanding contractual life (Years) Weighted average exercise price Aggregate intrinsic value Number exerciseable contractual life (Years) Weighted average exercise price Aggregate intrinsic value 1,701,107 6.61 $ 5.07 $ 11,612,717 1,198,594 5.51 $ 3.64 $ 9,819,736 The intrinsic value for stock options is defined as the difference between the current market value and the exercise price. The total intrinsic value of 98,574 658,000 20,205 87,000 (d) Restricted Common Stock In 2010, the Company issued 112,720 In September 2013, the Company issued 12,000 A dditionally, restricted shares issued to two members of the board of directors were further modified upon their retirement on January 6, 2014 to fully vest unvested restricted shares. Compensation expense was recorded as a result of the modifications (see note 8(b)). The grant date fair value of these shares when issued was $ 5.75 The Company includes unvested restricted stock in outstanding shares for financial reporting purposes when the awards vest. Number of unvested restricted shares Balance at December 31, 2014 7,000 Granted - Vested (3,000) Cancelled - Balance at September 30, 2015 4,000 (e) Restricted Stock Units On December 10, 2013, the Company issued 15,000 (f) Warrants F or charitable purposes, on December 23, 2003, the Company granted warrants to a local university for 20,467 12.21 |