Candriam Luxembourg S.C.A. 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
10X GENOMICS INC	CL A COM	88025U109	720	3,676	SH		SOLE		3,676	0	0
3M CO	COM	88579Y101	37,640	189,497	SH		SOLE		189,497	0	0
89BIO INC	COM	282559103	6,984	373,473	SH		SOLE		373,473	0	0
ABBOTT LABS	COM	002824100	76,575	660,529	SH		SOLE		660,529	0	0
ABBOTT LABS	COM	002824100	2	15	SH		OTR	1	0	0	15
ABBVIE INC	COM	00287Y109	1	13	SH		OTR	1	0	0	13
ABBVIE INC	COM	00287Y109	39,632	351,843	SH		SOLE		351,843	0	0
ABIOMED INC	COM	003654100	238	764	SH		SOLE		764	0	0
ACADIA PHARMACEUTICALS INC	COM	004225108	6,721	275,560	SH		SOLE		275,560	0	0
ACCELERON PHARMA INC	COM	00434H108	3	20	SH		OTR	1	0	0	20
ACCELERON PHARMA INC	COM	00434H108	69,902	557,035	SH		SOLE		557,035	0	0
ACCENTURE PLC IRELAND	SHS CLASS A	G1151C101	1	4	SH		OTR	1	0	0	4
ACHILLES THERAPEUTICS PLC	SPONSORED ADS	00449L102	0	12	SH		OTR	1	0	0	12
ACHILLES THERAPEUTICS PLC	SPONSORED ADS	00449L102	1,582	161,612	SH		SOLE		161,612	0	0
ACTIVISION BLIZZARD INC	COM	00507V109	29,914	313,429	SH		SOLE		313,429	0	0
ADOBE SYSTEMS INCORPORATED	COM	00724F101	121,813	208,000	SH		SOLE		208,000	0	0
ADOBE SYSTEMS INCORPORATED	COM	00724F101	2	4	SH		OTR	1	0	0	4
ADVANCED DRAIN SYS INC DEL	COM	00790R104	42,414	363,850	SH		SOLE		363,850	0	0
ADVANCED DRAIN SYS INC DEL	COM	00790R104	4	38	SH		OTR	1	0	0	38
ADVANCED MICRO DEVICES INC	COM	007903107	80,803	860,243	SH		SOLE		860,243	0	0
ADVANCED MICRO DEVICES INC	COM	007903107	2	18	SH		OTR	1	0	0	18
AFLAC INC	COM	001055102	3,173	59,131	SH		SOLE		59,131	0	0
AFLAC INC	COM	001055102	4	74	SH		OTR	1	0	0	74
AGILE THERAPEUTICS INC	COM	00847L100	39	29,000	SH		SOLE		29,000	0	0
AGILENT TECHNOLOGIES INC	COM	00846U101	7	46	SH		OTR	1	0	0	46
AGILENT TECHNOLOGIES INC	COM	00846U101	91,063	616,082	SH		SOLE		616,082	0	0
AGNICO EAGLE MINES LTD	COM	008474108	483	7,982	SH		SOLE		7,982	0	0
AILERON THERAPEUTICS INC	COM	00887A105	28	22,556	SH		SOLE		22,556	0	0
AIR PRODS & CHEMS INC	COM	009158106	71,625	248,973	SH		SOLE		248,973	0	0
AIR PRODS & CHEMS INC	COM	009158106	5	19	SH		OTR	1	0	0	19
AIRBNB INC	COM CL A	009066101	4,557	29,759	SH		SOLE		29,759	0	0
AKAMAI TECHNOLOGIES INC	COM	00971T101	1,957	16,784	SH		SOLE		16,784	0	0
AKAMAI TECHNOLOGIES INC	NOTE 0.125% 5/0	00971TAJ0	1,312	1,000	PRN		SOLE		1,000	0	0
AKAMAI TECHNOLOGIES INC	NOTE 0.375% 9/0	00971TAL5	1,860	1,600	PRN		SOLE		1,600	0	0
AKERO THERAPEUTICS INC	COM	00973Y108	3,143	126,667	SH		SOLE		126,667	0	0
ALBEMARLE CORP	COM	012653101	1,144	6,789	SH		SOLE		6,789	0	0
ALDEYRA THERAPEUTICS INC	COM	01438T106	1,586	140,000	SH		SOLE		140,000	0	0
ALEXANDRIA REAL ESTATE EQ IN	COM	015271109	1,763	9,691	SH		SOLE		9,691	0	0
ALEXION PHARMACEUTICALS INC	COM	015351109	92,500	503,510	SH		SOLE		503,510	0	0
ALIBABA GROUP HLDG LTD	SPONSORED ADS	01609W102	107,966	476,086	SH		SOLE		476,086	0	0
ALIBABA GROUP HLDG LTD	SPONSORED ADS	01609W102	2	7	SH		OTR	1	0	0	7
ALIGN TECHNOLOGY INC	COM	016255101	18,052	29,545	SH		SOLE		29,545	0	0
ALLAKOS INC	COM	01671P100	5,639	66,054	SH		SOLE		66,054	0	0
ALLAKOS INC	COM	01671P100	1,566	1,400	PRN		SOLE		1,400	0	0
ALLEGHANY CORP MD	COM	017175100	3,501	3,750	PRN		SOLE		3,750	0	0
ALLEGHANY CORP MD	COM	017175100	16,731	25,082	SH		SOLE		25,082	0	0
ALLSTATE CORP	COM	020002101	2	15	SH		OTR	1	0	0	15
ALLSTATE CORP	COM	020002101	4,370	33,501	SH		SOLE		33,501	0	0
ALLY FINL INC	COM	02005N100	16,611	333,287	SH		SOLE		333,287	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	29,636	174,822	SH		SOLE		174,822	0	0
ALPHABET INC	CAP STK CL A	02079K305	442,738	181,317	SH		SOLE		181,317	0	0
ALPHABET INC	CAP STK CL A	02079K305	17	7	SH		OTR	1	0	0	7
ALPHABET INC	CAP STK CL C	02079K107	116,231	46,375	SH		SOLE		46,375	0	0
ALTERYX INC	COM CL A	02156B103	2,230	25,923	SH		SOLE		25,923	0	0
AMAZON COM INC	COM	023135106	143,709	41,774	SH		SOLE		41,774	0	0
AMBARELLA INC	SHS	G037AX101	21,033	197,248	SH		SOLE		197,248	0	0
AMERESCO INC	CL A	02361E108	3	42	SH		OTR	1	0	0	42
AMERESCO INC	CL A	02361E108	23,047	367,464	SH		SOLE		367,464	0	0
AMERICAN AIRLS GROUP INC	COM	02376R102	276	13,000	SH		SOLE		13,000	0	0
AMERICAN EAGLE OUTFITTERS IN	COM	02553E106	7,103	189,260	SH		SOLE		189,260	0	0
AMERICAN EXPRESS CO	COM	025816109	8,710	52,714	SH		SOLE		52,714	0	0
AMERICAN EXPRESS CO	COM	025816109	2	15	SH		OTR	1	0	0	15
AMERICAN INTL GROUP INC	COM NEW	026874784	2,941	61,788	SH		SOLE		61,788	0	0
AMERICAN TOWER CORP NEW	COM	03027X100	10,000	37,018	SH		SOLE		37,018	0	0
AMERICAN WTR WKS CO INC NEW	COM	030420103	60,101	389,940	SH		SOLE		389,940	0	0
AMERICAN WTR WKS CO INC NEW	COM	030420103	4	29	SH		OTR	1	0	0	29
AMERIPRISE FINL INC	COM	03076C106	2	10	SH		OTR	1	0	0	10
AMERIPRISE FINL INC	COM	03076C106	3,652	14,672	SH		SOLE		14,672	0	0
AMERISOURCEBERGEN CORP	COM	03073E105	1,362	11,895	SH		SOLE		11,895	0	0
AMETEK INC	COM	031100100	3,266	24,462	SH		SOLE		24,462	0	0
AMGEN INC	COM	031162100	234,883	963,624	SH		SOLE		963,624	0	0
AMGEN INC	COM	031162100	8	33	SH		OTR	1	0	0	33
AMPHENOL CORP NEW	CL A	032095101	2,830	41,369	SH		SOLE		41,369	0	0
ANALOG DEVICES INC	COM	032654105	45,096	261,941	SH		SOLE		261,941	0	0
ANDERSONS INC	COM	034164103	213	6,973	SH		SOLE		6,973	0	0
ANNALY CAPITAL MANAGEMENT IN	COM	035710409	1,010	113,705	SH		SOLE		113,705	0	0
ANSYS INC	COM	03662Q105	2	6	SH		OTR	1	0	0	6
ANSYS INC	COM	03662Q105	53,643	154,565	SH		SOLE		154,565	0	0
ANTHEM INC	COM	036752103	21,705	56,848	SH		SOLE		56,848	0	0
ANTHEM INC	COM	036752103	1	3	SH		OTR	1	0	0	3
APELLIS PHARMACEUTICALS INC	COM	03753U106	20,054	317,315	SH		SOLE		317,315	0	0
APOLLO GLOBAL MGMT INC	COM CL A	03768E105	762	12,250	SH		SOLE		12,250	0	0
APPLE INC	COM	037833100	22	160	SH		OTR	1	0	0	160
APPLE INC	COM	037833100	470,248	3,433,467	SH		SOLE		3,433,467	0	0
APPLIED MATLS INC	COM	038222105	91,380	641,716	SH		SOLE		641,716	0	0
APPLIED MATLS INC	COM	038222105	2	11	SH		OTR	1	0	0	11
APTIV PLC	SHS	G6095L109	5	31	SH		OTR	1	0	0	31
ARCH CAP GROUP LTD	ORD	G0450A105	881	22,622	SH		SOLE		22,622	0	0
ARCHER DANIELS MIDLAND CO	COM	039483102	1	18	SH		OTR	1	0	0	18
ARCHER DANIELS MIDLAND CO	COM	039483102	1,533	25,290	SH		SOLE		25,290	0	0
ARDELYX INC	COM	039697107	6,453	851,291	SH		SOLE		851,291	0	0
ARENA PHARMACEUTICALS INC	COM NEW	040047607	42,715	626,318	SH		SOLE		626,318	0	0
ARGENX SE	SPONSORED ADR	04016X101	14,911	49,526	SH		SOLE		49,526	0	0
ARISTA NETWORKS INC	COM	040413106	1,133	3,128	SH		SOLE		3,128	0	0
ARK ETF TR	GENOMIC REV ETF	00214Q302	808	8,740	SH		SOLE		8,740	0	0
ARK ETF TR	INNOVATION ETF	00214Q104	923	7,060	SH		SOLE		7,060	0	0
ARROW ELECTRS INC	COM	042735100	3	22	SH		OTR	1	0	0	22
ARROWHEAD PHARMACEUTICALS IN	COM	04280A100	16,267	196,408	SH		SOLE		196,408	0	0
ARVINAS INC	COM	04335A105	19,296	250,593	SH		SOLE		250,593	0	0
ARVINAS INC	COM	04335A105	1	10	SH		OTR	1	0	0	10
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	37,226	282,980	SH		SOLE		282,980	0	0
ASSEMBLY BIOSCIENCES INC	COM	045396108	4,321	1,113,754	SH		SOLE		1,113,754	0	0
ASSURANT INC	COM	04621X108	1,700	10,885	SH		SOLE		10,885	0	0
ASSURANT INC	COM	04621X108	1	7	SH		OTR	1	0	0	7
ASTRAZENECA PLC	SPONSORED ADR	046353108	15	246	SH		OTR	1	0	0	246
ASTRAZENECA PLC	SPONSORED ADR	046353108	15,403	257,140	SH		SOLE		257,140	0	0
ASURE SOFTWARE INC	COM	04649U102	231	26,000	SH		SOLE		26,000	0	0
AT HOME GROUP INC	COM	04650Y100	3,437	93,286	SH		SOLE		93,286	0	0
AT&T INC	COM	00206R102	6	213	SH		OTR	1	0	0	213
AT&T INC	COM	00206R102	13,923	483,760	SH		SOLE		483,760	0	0
ATHENE HOLDING LTD	CL A	G0684D107	14,787	219,060	SH		SOLE		219,060	0	0
ATMOS ENERGY CORP	COM	049560105	2	21	SH		OTR	1	0	0	21
ATMOS ENERGY CORP	COM	049560105	6,845	71,220	SH		SOLE		71,220	0	0
ATRECA INC	CL A COM	04965G109	0	25	SH		OTR	1	0	0	25
ATRECA INC	CL A COM	04965G109	3,184	373,681	SH		SOLE		373,681	0	0
AUTODESK INC	COM	052769106	2	7	SH		OTR	1	0	0	7
AUTODESK INC	COM	052769106	64,531	221,072	SH		SOLE		221,072	0	0
AUTOMATIC DATA PROCESSING IN	COM	053015103	24,982	125,778	SH		SOLE		125,778	0	0
AUTOZONE INC	COM	053332102	2,301	1,542	SH		SOLE		1,542	0	0
AVALARA INC	COM	05338G106	730	4,510	SH		SOLE		4,510	0	0
AVALONBAY CMNTYS INC	COM	053484101	2,641	12,654	SH		SOLE		12,654	0	0
AVANTOR INC	COM	05352A100	12,523	352,662	SH		SOLE		352,662	0	0
AVERY DENNISON CORP	COM	053611109	6,589	31,341	SH		SOLE		31,341	0	0
AVIDITY BIOSCIENCES INC	COM	05370A108	3,953	159,988	SH		SOLE		159,988	0	0
AXSOME THERAPEUTICS INC	COM	05464T104	8,001	118,602	SH		SOLE		118,602	0	0
BAIDU INC	SPON ADR REP A	056752108	38,861	190,589	SH		SOLE		190,589	0	0
BAKER HUGHES COMPANY	CL A	05722G100	1,241	54,262	SH		SOLE		54,262	0	0
BALL CORP	COM	058498106	3	40	SH		OTR	1	0	0	40
BALL CORP	COM	058498106	34,303	423,394	SH		SOLE		423,394	0	0
BALLARD PWR SYS INC NEW	COM	058586108	4,061	224,096	SH		SOLE		224,096	0	0
BANCO BILBAO VIZCAYA ARGENTA	SPONSORED ADR	05946K101	2	307	SH		OTR	1	0	0	307
BANCO BRADESCO S A	SP ADR PFD NEW	059460303	811	158,010	SH		SOLE		158,010	0	0
BANK MONTREAL QUE	COM	063671101	19,355	188,625	SH		SOLE		188,625	0	0
BANK NEW YORK MELLON CORP	COM	064058100	3,482	67,965	SH		SOLE		67,965	0	0
BANK NEW YORK MELLON CORP	COM	064058100	1	27	SH		OTR	1	0	0	27
BANK NOVA SCOTIA B C	COM	064149107	30,224	464,238	SH		SOLE		464,238	0	0
BARRICK GOLD CORP	COM	067901108	1,786	86,278	SH		SOLE		86,278	0	0
BAXTER INTL INC	COM	071813109	4,162	51,699	SH		SOLE		51,699	0	0
BCE INC	COM NEW	05534B760	279	5,644	SH		SOLE		5,644	0	0
BEAM THERAPEUTICS INC	COM	07373V105	9,930	77,147	SH		SOLE		77,147	0	0
BECTON DICKINSON & CO	COM	075887109	15,592	64,115	SH		SOLE		64,115	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	44,817	130,590	SH		SOLE		130,590	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	2	5	SH		OTR	1	0	0	5
BERKLEY W R CORP	COM	084423102	528	7,092	SH		SOLE		7,092	0	0
BERKSHIRE HATHAWAY INC DEL	CL B NEW	084670702	31,430	113,090	SH		SOLE		113,090	0	0
BEST BUY INC	COM	086516101	26,325	228,955	SH		SOLE		228,955	0	0
BEST BUY INC	COM	086516101	1,068	800	PRN		SOLE		800	0	0
BHP GROUP LTD	SPONSORED ADS	088606108	5	75	SH		OTR	1	0	0	75
BHP GROUP PLC	SPONSORED ADR	05545E209	1	23	SH		OTR	1	0	0	23
BILIBILI INC	SPONS ADS REP Z	090040106	17,539	143,950	SH		SOLE		143,950	0	0
BIO RAD LABS INC	CL A	090572207	2	3	SH		OTR	1	0	0	3
BIO RAD LABS INC	CL A	090572207	36,889	57,255	SH		SOLE		57,255	0	0
BIOATLA INC	COM	09077B104	0	7	SH		OTR	1	0	0	7
BIOATLA INC	COM	09077B104	5,492	129,591	SH		SOLE		129,591	0	0
BIOGEN INC	COM	09062X103	95,238	275,040	SH		SOLE		275,040	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	4,563	47,005	SH		SOLE		47,005	0	0
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	8,998	107,843	SH		SOLE		107,843	0	0
BIOMARIN PHARMACEUTICAL INC	NOTE 0.599% 8/0	09061GAH4	835	800	PRN		SOLE		800	0	0
BIONTECH SE	SPONSORED ADS	09075V102	23,305	104,097	SH		SOLE		104,097	0	0
BIO-TECHNE CORP	COM	09073M104	27,605	61,309	SH		SOLE		61,309	0	0
BIO-TECHNE CORP	COM	09073M104	2	4	SH		OTR	1	0	0	4
BK OF AMERICA CORP	COM	060505104	9	224	SH		OTR	1	0	0	224
BK OF AMERICA CORP	COM	060505104	88,056	2,135,715	SH		SOLE		2,135,715	0	0
BLACKBERRY LTD	COM	09228F103	183	15,000	SH		SOLE		15,000	0	0
BLACKROCK INC	COM	09247X101	9,977	11,403	SH		SOLE		11,403	0	0
BLACKSTONE GROUP INC	COM	09260D107	3,303	34,000	SH		SOLE		34,000	0	0
BLINK CHARGING CO	COM	09354A100	7,259	176,317	SH		SOLE		176,317	0	0
BLINK CHARGING CO	COM	09354A100	1	25	SH		OTR	1	0	0	25
BLOOM ENERGY CORP	COM CL A	093712107	15,108	562,250	SH		SOLE		562,250	0	0
BLOOM ENERGY CORP	COM CL A	093712107	2	61	SH		OTR	1	0	0	61
BLUEPRINT MEDICINES CORP	COM	09627Y109	1	13	SH		OTR	1	0	0	13
BLUEPRINT MEDICINES CORP	COM	09627Y109	27,526	312,937	SH		SOLE		312,937	0	0
BOOKING HOLDINGS INC	COM	09857L108	49,381	22,568	SH		SOLE		22,568	0	0
BOOKING HOLDINGS INC	COM	09857L108	2	1	SH		OTR	1	0	0	1
BOSTON BEER INC	CL A	100557107	551	540	SH		SOLE		540	0	0
BOSTON PROPERTIES INC	COM	101121101	1,723	15,037	SH		SOLE		15,037	0	0
BOSTON SCIENTIFIC CORP	COM	101137107	3,554	83,117	SH		SOLE		83,117	0	0
BP PLC	SPONSORED ADR	055622104	1	47	SH		OTR	1	0	0	47
BRIDGEBIO PHARMA INC	COM	10806X102	27,754	455,285	SH		SOLE		455,285	0	0
BRINKS CO	COM	109696104	1,459	18,982	SH		SOLE		18,982	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	26,687	399,383	SH		SOLE		399,383	0	0
BROADCOM INC	COM	11135F101	21,304	44,677	SH		SOLE		44,677	0	0
BROADRIDGE FINL SOLUTIONS IN	COM	11133T103	849	5,257	SH		SOLE		5,257	0	0
BROOKFIELD ASSET MGMT INC	CL A LTD VT SH	112585104	1,888	36,973	SH		SOLE		36,973	0	0
BROOKFIELD RENEWABLE PARTNER	PARTNERSHIP UNIT	G16258108	1,421	36,839	SH		SOLE		36,839	0	0
BROWN FORMAN CORP	CL B	115637209	1,726	23,032	SH		SOLE		23,032	0	0
BRUKER CORP	COM	116794108	4,720	62,128	SH		SOLE		62,128	0	0
BUNGE LIMITED	COM	G16962105	11,260	144,082	SH		SOLE		144,082	0	0
BURLINGTON STORES INC	COM	122017106	1,121	3,483	SH		SOLE		3,483	0	0
CADENCE DESIGN SYSTEM INC	COM	127387108	4	28	SH		OTR	1	0	0	28
CADENCE DESIGN SYSTEM INC	COM	127387108	24,385	178,224	SH		SOLE		178,224	0	0
CAESARS ENTERTAINMENT INC NE	COM	12769G100	1,120	10,795	SH		SOLE		10,795	0	0
CAMPBELL SOUP CO	COM	134429109	773	16,950	SH		SOLE		16,950	0	0
CANADIAN IMP BK COMM	COM	136069101	1,317	11,560	SH		SOLE		11,560	0	0
CANADIAN NAT RES LTD	COM	136385101	699	19,245	SH		SOLE		19,245	0	0
CANADIAN NATL RY CO	COM	136375102	4,430	41,938	SH		SOLE		41,938	0	0
CANADIAN PAC RY LTD	COM	13645T100	1,354	17,590	SH		SOLE		17,590	0	0
CAPITAL ONE FINL CORP	COM	14040H105	6,370	41,178	SH		SOLE		41,178	0	0
CARDINAL HEALTH INC	COM	14149Y108	1,549	27,124	SH		SOLE		27,124	0	0
CARDINAL HEALTH INC	COM	14149Y108	1	26	SH		OTR	1	0	0	26
CARMAX INC	COM	143130102	1,089	8,434	SH		SOLE		8,434	0	0
CARNIVAL CORP	UNIT 99/99/9999	143658300	1,286	48,790	SH		SOLE		48,790	0	0
CARRIER GLOBAL CORPORATION	COM	14448C104	2,760	56,785	SH		SOLE		56,785	0	0
CATALENT INC	COM	148806102	4,391	40,616	SH		SOLE		40,616	0	0
CATERPILLAR INC	COM	149123101	12,911	59,327	SH		SOLE		59,327	0	0
CBOE GLOBAL MKTS INC	COM	12503M108	670	5,631	SH		SOLE		5,631	0	0
CBRE GROUP INC	CL A	12504L109	27,379	319,364	SH		SOLE		319,364	0	0
CDW CORP	COM	12514G108	3,966	22,706	SH		SOLE		22,706	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	13,365	399,685	SH		SOLE		399,685	0	0
CENTENE CORP DEL	COM	15135B101	2,579	35,362	SH		SOLE		35,362	0	0
CENTERPOINT ENERGY INC	COM	15189T107	1,567	63,910	SH		SOLE		63,910	0	0
CENTURY BANCORPORATION INC	CL A NON VTG	156432106	2,323	20,378	SH		SOLE		20,378	0	0
CERENCE INC	COM	156727109	19,272	180,600	SH		SOLE		180,600	0	0
CERIDIAN HCM HLDG INC	COM	15677J108	674	7,025	SH		SOLE		7,025	0	0
CERNER CORP	COM	156782104	6,158	78,790	SH		SOLE		78,790	0	0
CERNER CORP	COM	156782104	2	20	SH		OTR	1	0	0	20
CEVA INC	COM	157210105	17,069	360,869	SH		SOLE		360,869	0	0
CF INDS HLDGS INC	COM	125269100	597	11,604	SH		SOLE		11,604	0	0
CGI INC	CL A SUB VTG	12532H104	3,075	33,879	SH		SOLE		33,879	0	0
CHANGE HEALTHCARE INC	COM	15912K100	12,763	553,958	SH		SOLE		553,958	0	0
CHARLES RIV LABS INTL INC	COM	159864107	3	9	SH		OTR	1	0	0	9
CHARLES RIV LABS INTL INC	COM	159864107	88,092	238,138	SH		SOLE		238,138	0	0
CHARTER COMMUNICATIONS INC N	CL A	16119P108	8,735	12,108	SH		SOLE		12,108	0	0
CHENIERE ENERGY INC	COM NEW	16411R208	1,475	17,006	SH		SOLE		17,006	0	0
CHEVRON CORP NEW	COM	166764100	3,941	37,628	SH		SOLE		37,628	0	0
CHIASMA INC	COM	16706W102	111	23,500	SH		SOLE		23,500	0	0
CHINOOK THERAPEUTICS INC	COM	16961L106	12,357	875,124	SH		SOLE		875,124	0	0
CHIPOTLE MEXICAN GRILL INC	COM	169656105	28,740	18,538	SH		SOLE		18,538	0	0
CHUNGHWA TELECOM CO LTD	SPON ADR NEW11	17133Q502	386	9,483	SH		SOLE		9,483	0	0
CHURCH & DWIGHT INC	COM	171340102	2,759	32,374	SH		SOLE		32,374	0	0
CHURCH & DWIGHT INC	COM	171340102	2	19	SH		OTR	1	0	0	19
CI FINL CORP	COM	125491100	343	18,696	SH		SOLE		18,696	0	0
CIA ENERGETICA DE MINAS GERA	SP ADR N-V PFD	204409601	188	78,834	SH		SOLE		78,834	0	0
CIGNA CORP NEW	COM	125523100	8,958	37,786	SH		SOLE		37,786	0	0
CIGNA CORP NEW	COM	125523100	2	8	SH		OTR	1	0	0	8
CINCINNATI BELL INC NEW	COM NEW	171871502	2,559	165,973	SH		SOLE		165,973	0	0
CINCINNATI FINL CORP	COM	172062101	2,233	19,144	SH		SOLE		19,144	0	0
CINTAS CORP	COM	172908105	2,784	7,287	SH		SOLE		7,287	0	0
CISCO SYS INC	COM	17275R102	1,013	1,000	PRN		SOLE		1,000	0	0
CISCO SYS INC	COM	17275R102	37,986	716,709	SH		SOLE		716,709	0	0
CISCO SYS INC	COM	17275R102	4	77	SH		OTR	1	0	0	77
CIT GROUP INC	COM NEW	125581801	2,887	55,952	SH		SOLE		55,952	0	0
CITIGROUP INC	COM NEW	172967424	7	93	SH		OTR	1	0	0	93
CITIGROUP INC	COM NEW	172967424	103,587	1,464,121	SH		SOLE		1,464,121	0	0
CITIZENS FINL GROUP INC	COM	174610105	12,530	273,158	SH		SOLE		273,158	0	0
CITRIX SYS INC	COM	177376100	1,427	12,165	SH		SOLE		12,165	0	0
CLOROX CO DEL	COM	189054109	1,039	1,000	PRN		SOLE		1,000	0	0
CLOROX CO DEL	COM	189054109	3,450	19,177	SH		SOLE		19,177	0	0
CLOUDERA INC	COM	18914U100	12,272	773,774	SH		SOLE		773,774	0	0
CME GROUP INC	COM	12572Q105	5,163	24,278	SH		SOLE		24,278	0	0
CNO FINL GROUP INC	COM	12621E103	6,784	287,217	SH		SOLE		287,217	0	0
COCA COLA CO	COM	191216100	49,867	921,581	SH		SOLE		921,581	0	0
COGENT BIOSCIENCES INC	COM	19240Q201	15,495	1,910,601	SH		SOLE		1,910,601	0	0
COGENT BIOSCIENCES INC	COM	19240Q201	1	119	SH		OTR	1	0	0	119
COGNEX CORP	COM	192422103	799	9,505	SH		SOLE		9,505	0	0
COGNIZANT TECHNOLOGY SOLUTIO	CL A	192446102	2,570	37,113	SH		SOLE		37,113	0	0
COHERENT INC	COM	192479103	12,097	45,763	SH		SOLE		45,763	0	0
COLGATE PALMOLIVE CO	COM	194162103	21,080	259,124	SH		SOLE		259,124	0	0
COLGATE PALMOLIVE CO	COM	194162103	2	19	SH		OTR	1	0	0	19
COMCAST CORP NEW	CL A	20030N101	40,294	706,673	SH		SOLE		706,673	0	0
COMCAST CORP NEW	CL A	20030N101	5	95	SH		OTR	1	0	0	95
COMERICA INC	COM	200340107	621	8,711	SH		SOLE		8,711	0	0
CONAGRA BRANDS INC	COM	205887102	1,415	38,887	SH		SOLE		38,887	0	0
CONOCOPHILLIPS	COM	20825C104	5,986	98,286	SH		SOLE		98,286	0	0
CONSOLIDATED EDISON INC	COM	209115104	3,221	44,906	SH		SOLE		44,906	0	0
CONSTELLATION BRANDS INC	CL A	21036P108	3,064	13,100	SH		SOLE		13,100	0	0
CONSTELLATION PHARMCETICLS I	COM	210373106	9,464	280,008	SH		SOLE		280,008	0	0
CONTINENTAL RES INC	COM	212015101	209	5,506	SH		SOLE		5,506	0	0
COPART INC	COM	217204106	5,964	45,242	SH		SOLE		45,242	0	0
CORNING INC	COM	219350105	3,939	96,308	SH		SOLE		96,308	0	0
CORTEVA INC	COM	22052L104	1,093	24,638	SH		SOLE		24,638	0	0
COSTAR GROUP INC	COM	22160N109	1,881	22,710	SH		SOLE		22,710	0	0
COSTCO WHSL CORP NEW	COM	22160K105	29,279	73,998	SH		SOLE		73,998	0	0
COUPA SOFTWARE INC	COM	22266L106	1,425	5,438	SH		SOLE		5,438	0	0
COUPA SOFTWARE INC	NOTE 0.375% 6/1	22266LAF3	1,158	1,000	PRN		SOLE		1,000	0	0
CRH PLC	ADR	12626K203	3	50	SH		OTR	1	0	0	50
CRH PLC	ADR	12626K203	2,635	51,825	SH		SOLE		51,825	0	0
CROWDSTRIKE HLDGS INC	CL A	22788C105	2,375	9,449	SH		SOLE		9,449	0	0
CROWN CASTLE INTL CORP NEW	COM	22822V101	19,238	98,606	SH		SOLE		98,606	0	0
CROWN HLDGS INC	COM	228368106	2	18	SH		OTR	1	0	0	18
CROWN HLDGS INC	COM	228368106	1,811	17,717	SH		SOLE		17,717	0	0
CSX CORP	COM	126408103	8,254	257,292	SH		SOLE		257,292	0	0
CSX CORP	COM	126408103	2	57	SH		OTR	1	0	0	57
CUMMINS INC	COM	231021106	5,388	22,101	SH		SOLE		22,101	0	0
CURIS INC	COM NEW	231269200	1	105	SH		OTR	1	0	0	105
CURIS INC	COM NEW	231269200	20,014	2,480,058	SH		SOLE		2,480,058	0	0
CVS HEALTH CORP	COM	126650100	4	49	SH		OTR	1	0	0	49
CVS HEALTH CORP	COM	126650100	27,375	328,083	SH		SOLE		328,083	0	0
CVS HEALTH CORP	COM	126650100	537	450	PRN		SOLE		450	0	0
CYTOKINETICS INC	COM NEW	23282W605	10,159	513,344	SH		SOLE		513,344	0	0
CYTOMX THERAPEUTICS INC	COM	23284F105	14,738	2,328,201	SH		SOLE		2,328,201	0	0
CYTOMX THERAPEUTICS INC	COM	23284F105	1	152	SH		OTR	1	0	0	152
D R HORTON INC	COM	23331A109	3,590	39,723	SH		SOLE		39,723	0	0
DANAHER CORPORATION	COM	235851102	15	56	SH		OTR	1	0	0	56
DANAHER CORPORATION	COM	235851102	231,082	861,091	SH		SOLE		861,091	0	0
DARDEN RESTAURANTS INC	COM	237194105	1,709	11,703	SH		SOLE		11,703	0	0
DARLING INGREDIENTS INC	COM	237266101	2	34	SH		OTR	1	0	0	34
DARLING INGREDIENTS INC	COM	237266101	30,813	456,482	SH		SOLE		456,482	0	0
DATADOG INC	CL A COM	23804L103	1,245	11,960	SH		SOLE		11,960	0	0
DATADOG INC	NOTE 0.125% 6/1	23804LAB9	669	500	PRN		SOLE		500	0	0
DAVITA INC	COM	23918K108	7,922	65,777	SH		SOLE		65,777	0	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	25,923	708,090	SH		SOLE		708,090	0	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	1	27	SH		OTR	1	0	0	27
DEERE & CO	COM	244199105	10,673	30,261	SH		SOLE		30,261	0	0
DELL TECHNOLOGIES INC	CL C	24703L202	4,604	46,195	SH		SOLE		46,195	0	0
DENALI THERAPEUTICS INC	COM	24823R105	5,003	63,781	SH		SOLE		63,781	0	0
DENTSPLY SIRONA INC	COM	24906P109	1,026	16,212	SH		SOLE		16,212	0	0
DEVON ENERGY CORP NEW	COM	25179M103	1,856	63,572	SH		SOLE		63,572	0	0
DEXCOM INC	COM	252131107	2,365	5,539	SH		SOLE		5,539	0	0
DIAGEO PLC	SPON ADR NEW	25243Q205	3	17	SH		OTR	1	0	0	17
DIAGEO PLC	SPON ADR NEW	25243Q205	3,456	18,029	SH		SOLE		18,029	0	0
DIAGEO PLC	SPON ADR NEW	25243Q205	5,597	5,400	PRN		SOLE		5,400	0	0
DIAMONDBACK ENERGY INC	COM	25278X109	634	6,752	SH		SOLE		6,752	0	0
DICERNA PHARMACEUTICALS INC	COM	253031108	15,609	418,245	SH		SOLE		418,245	0	0
DIGITAL RLTY TR INC	COM	253868103	11,371	75,574	SH		SOLE		75,574	0	0
DIGITAL TURBINE INC	COM NEW	25400W102	4,480	58,930	SH		SOLE		58,930	0	0
DISCOVER FINL SVCS	COM	254709108	2,973	25,130	SH		SOLE		25,130	0	0
DISCOVERY INC	COM SER C	25470F302	852	29,404	SH		SOLE		29,404	0	0
DISH NETWORK CORPORATION	CL A	25470M109	515	12,321	SH		SOLE		12,321	0	0
DISNEY WALT CO	COM	254687106	88,191	501,740	SH		SOLE		501,740	0	0
DISNEY WALT CO	COM	254687106	8	45	SH		OTR	1	0	0	45
DOCUSIGN INC	COM	256163106	17,617	63,014	SH		SOLE		63,014	0	0
DOLLAR GEN CORP NEW	COM	256677105	9,840	45,475	SH		SOLE		45,475	0	0
DOLLAR TREE INC	COM	256746108	1,252	12,578	SH		SOLE		12,578	0	0
DOMINION ENERGY INC	COM	25746U109	4,216	57,300	SH		SOLE		57,300	0	0
DOMINION ENERGY INC	COM	25746U109	2,332	2,000	PRN		SOLE		2,000	0	0
DOMINOS PIZZA INC	COM	25754A201	807	1,731	SH		SOLE		1,731	0	0
DOMTAR CORP	COM NEW	257559203	17,367	315,996	SH		SOLE		315,996	0	0
DOVER CORP	COM	260003108	2,945	19,556	SH		SOLE		19,556	0	0
DOVER CORP	COM	260003108	1	9	SH		OTR	1	0	0	9
DOW INC	COM	260557103	5,271	83,300	SH		SOLE		83,300	0	0
DROPBOX INC	CL A	26210C104	5,592	184,507	SH		SOLE		184,507	0	0
DUKE REALTY CORP	COM NEW	264411505	2,533	53,495	SH		SOLE		53,495	0	0
DUPONT DE NEMOURS INC	COM	26614N102	15,735	203,265	SH		SOLE		203,265	0	0
DYNE THERAPEUTICS INC	COM	26818M108	6,804	323,393	SH		SOLE		323,393	0	0
EARGO INC	COM	270087109	395	9,898	SH		SOLE		9,898	0	0
EATON CORP PLC	SHS	G29183103	2	16	SH		OTR	1	0	0	16
EBAY INC.	COM	278642103	5,300	75,483	SH		SOLE		75,483	0	0
ECOLAB INC	COM	278865100	13,699	66,509	SH		SOLE		66,509	0	0
EDISON INTL	COM	281020107	3,178	54,966	SH		SOLE		54,966	0	0
EDWARDS LIFESCIENCES CORP	COM	28176E108	11,691	112,878	SH		SOLE		112,878	0	0
ELANCO ANIMAL HEALTH INC	COM	28414H103	780	22,491	SH		SOLE		22,491	0	0
ELECTRONIC ARTS INC	COM	285512109	10,905	75,819	SH		SOLE		75,819	0	0
EMCOR GROUP INC	COM	29084Q100	3,109	25,238	SH		SOLE		25,238	0	0
EMERSON ELEC CO	COM	291011104	63,816	663,093	SH		SOLE		663,093	0	0
ENBRIDGE INC	COM	29250N105	1,871	46,691	SH		SOLE		46,691	0	0
ENPHASE ENERGY INC	COM	29355A107	27,896	151,915	SH		SOLE		151,915	0	0
ENPHASE ENERGY INC	COM	29355A107	3	15	SH		OTR	1	0	0	15
ENTERGY CORP NEW	COM	29364G103	1,169	11,724	SH		SOLE		11,724	0	0
ENVIVA PARTNERS LP	COM UNIT	29414J107	3,485	66,496	SH		SOLE		66,496	0	0
EOG RES INC	COM	26875P101	2,898	34,735	SH		SOLE		34,735	0	0
EPIZYME INC	COM	29428V104	551	66,329	SH		SOLE		66,329	0	0
EQUIFAX INC	COM	294429105	1,624	6,782	SH		SOLE		6,782	0	0
EQUINIX INC	COM	29444U700	3	4	SH		OTR	1	0	0	4
EQUINIX INC	COM	29444U700	44,018	54,844	SH		SOLE		54,844	0	0
EQUINOR ASA	SPONSORED ADR	29446M102	1	66	SH		OTR	1	0	0	66
EQUITY LIFESTYLE PPTYS INC	COM	29472R108	819	11,027	SH		SOLE		11,027	0	0
EQUITY LIFESTYLE PPTYS INC	COM	29472R108	3	46	SH		OTR	1	0	0	46
EQUITY RESIDENTIAL	SH BEN INT	29476L107	2,209	2,000	PRN		SOLE		2,000	0	0
EQUITY RESIDENTIAL	SH BEN INT	29476L107	2,496	32,412	SH		SOLE		32,412	0	0
ERICSSON	ADR B SEK 10	294821608	1,917	152,392	SH		SOLE		152,392	0	0
ERICSSON	ADR B SEK 10	294821608	2	125	SH		OTR	1	0	0	125
ESSA PHARMA INC	COM NEW	29668H708	8,585	300,505	SH		SOLE		300,505	0	0
ESSA PHARMA INC	COM NEW	29668H708	1	20	SH		OTR	1	0	0	20
ESSENTIAL UTILS INC	COM	29670G102	1,632	35,712	SH		SOLE		35,712	0	0
ESSEX PPTY TR INC	COM	297178105	1,561	5,202	SH		SOLE		5,202	0	0
ETF MANAGERS TR	PRIME CYBR SCRTY	26924G201	1,317	21,715	SH		SOLE		21,715	0	0
ETF MANAGERS TR	WEDBUSH VID GAME	26924G706	318	3,335	SH		SOLE		3,335	0	0
ETSY INC	COM	29786A106	4,556	22,136	SH		SOLE		22,136	0	0
EVEREST RE GROUP LTD	COM	G3223R108	1,612	6,396	SH		SOLE		6,396	0	0
EVERSOURCE ENERGY	COM	30040W108	3,171	39,518	SH		SOLE		39,518	0	0
EXACT SCIENCES CORP	COM	30063P105	29,707	238,977	SH		SOLE		238,977	0	0
EXACT SCIENCES CORP	COM	30063P105	2	15	SH		OTR	1	0	0	15
EXACT SCIENCES CORP	NOTE 0.375% 3/0	30063PAC9	1,240	1,000	PRN		SOLE		1,000	0	0
EXCHANGE TRADED CONCEPTS TR	EMQQ EM INTERN	301505889	1,923	30,350	SH		SOLE		30,350	0	0
EXELIXIS INC	COM	30161Q104	2	125	SH		OTR	1	0	0	125
EXELIXIS INC	COM	30161Q104	50,430	2,767,822	SH		SOLE		2,767,822	0	0
EXELON CORP	COM	30161N101	5,580	125,933	SH		SOLE		125,933	0	0
EXPEDIA GROUP INC	COM NEW	30212P303	1,173	7,165	SH		SOLE		7,165	0	0
EXPEDITORS INTL WASH INC	COM	302130109	3,791	3,500	PRN		SOLE		3,500	0	0
EXPEDITORS INTL WASH INC	COM	302130109	1,679	13,265	SH		SOLE		13,265	0	0
EXPEDITORS INTL WASH INC	COM	302130109	3	20	SH		OTR	1	0	0	20
EXTRA SPACE STORAGE INC	COM	30225T102	955	5,827	SH		SOLE		5,827	0	0
EXXON MOBIL CORP	COM	30231G102	23,409	371,097	SH		SOLE		371,097	0	0
FACEBOOK INC	CL A	30303M102	176,159	506,625	SH		SOLE		506,625	0	0
FACEBOOK INC	CL A	30303M102	5	13	SH		OTR	1	0	0	13
FASTENAL CO	COM	311900104	2,941	56,562	SH		SOLE		56,562	0	0
FASTENAL CO	COM	311900104	2	29	SH		OTR	1	0	0	29
FATE THERAPEUTICS INC	COM	31189P102	1	8	SH		OTR	1	0	0	8
FATE THERAPEUTICS INC	COM	31189P102	21,761	250,729	SH		SOLE		250,729	0	0
FEDEX CORP	COM	31428X106	6,625	22,207	SH		SOLE		22,207	0	0
FERRO CORP	COM	315405100	2,667	123,663	SH		SOLE		123,663	0	0
FIBROGEN INC	COM	31572Q808	7,682	288,484	SH		SOLE		288,484	0	0
FIDELITY NATIONAL FINANCIAL	FNF GROUP COM	31620R303	796	18,311	SH		SOLE		18,311	0	0
FIDELITY NATL INFORMATION SV	COM	31620M106	6,660	47,008	SH		SOLE		47,008	0	0
FIFTH THIRD BANCORP	COM	316773100	5,319	139,132	SH		SOLE		139,132	0	0
FIRST REP BK SAN FRANCISCO C	COM	33616C100	1,899	10,145	SH		SOLE		10,145	0	0
FISERV INC	COM	337738108	4,863	45,495	SH		SOLE		45,495	0	0
FIVE BELOW INC	COM	33829M101	1,531	7,922	SH		SOLE		7,922	0	0
FLEETCOR TECHNOLOGIES INC	COM	339041105	1,102	4,302	SH		SOLE		4,302	0	0
FLUIDIGM CORP DEL	COM	34385P108	1,070	173,646	SH		SOLE		173,646	0	0
FLY LEASING LTD	SPONSORED ADR	34407D109	4,390	259,121	SH		SOLE		259,121	0	0
FMC CORP	COM NEW	302491303	1,464	13,530	SH		SOLE		13,530	0	0
FOMENTO ECONOMICO MEXICANO S	SPON ADR UNITS	344419106	294	3,484	SH		SOLE		3,484	0	0
FORD MTR CO DEL	COM	345370860	5,261	354,015	SH		SOLE		354,015	0	0
FORMA THERAPEUTICS HLDGS INC	SHS	34633R104	7,285	292,692	SH		SOLE		292,692	0	0
FORTERRA INC	COM	34960W106	17,277	734,897	SH		SOLE		734,897	0	0
FORTINET INC	COM	34959E109	1,494	6,273	SH		SOLE		6,273	0	0
FORTIS INC	COM	349553107	2,772	2,500	PRN		SOLE		2,500	0	0
FORTIVE CORP	COM	34959J108	3,251	46,612	SH		SOLE		46,612	0	0
FORTIVE CORP	NOTE 0.875% 2/1	34959JAK4	11,567	11,500	PRN		SOLE		11,500	0	0
FORTRESS BIOTECH INC	COM	34960Q109	80	22,500	SH		SOLE		22,500	0	0
FOX CORP	CL A COM	35137L105	504	13,565	SH		SOLE		13,565	0	0
FOX CORP	CL B COM	35137L204	1,001	28,435	SH		SOLE		28,435	0	0
FRANCO NEV CORP	COM	351858105	733	5,045	SH		SOLE		5,045	0	0
FRANKLIN RESOURCES INC	COM	354613101	1,354	42,328	SH		SOLE		42,328	0	0
FREEPORT-MCMORAN INC	CL B	35671D857	2,816	75,873	SH		SOLE		75,873	0	0
FRESHPET INC	COM	358039105	1,425	8,745	SH		SOLE		8,745	0	0
FTI CONSULTING INC	COM	302941109	6,293	46,066	SH		SOLE		46,066	0	0
GALLAGHER ARTHUR J & CO	COM	363576109	1,251	8,931	SH		SOLE		8,931	0	0
GAP INC	COM	364760108	368	10,937	SH		SOLE		10,937	0	0
GARMIN LTD	SHS	H2906T109	2	17	SH		OTR	1	0	0	17
GENERAC HLDGS INC	COM	368736104	4,366	10,517	SH		SOLE		10,517	0	0
GENERAL ELECTRIC CO	COM	369604103	9,319	692,340	SH		SOLE		692,340	0	0
GENERAL MLS INC	COM	370334104	12,980	213,039	SH		SOLE		213,039	0	0
GENERAL MTRS CO	COM	37045V100	6,539	110,515	SH		SOLE		110,515	0	0
GENMAB A/S	SPONSORED ADS	372303206	6	136	SH		OTR	1	0	0	136
GENUINE PARTS CO	COM	372460105	1,443	11,409	SH		SOLE		11,409	0	0
GILDAN ACTIVEWEAR INC	COM	375916103	5,340	144,574	SH		SOLE		144,574	0	0
GILEAD SCIENCES INC	COM	375558103	2	24	SH		OTR	1	0	0	24
GILEAD SCIENCES INC	COM	375558103	109,631	1,592,082	SH		SOLE		1,592,082	0	0
GLADSTONE COMMERCIAL CORP	COM	376536108	225	9,980	SH		SOLE		9,980	0	0
GLAXOSMITHKLINE PLC	SPONSORED ADR	37733W105	4	92	SH		OTR	1	0	0	92
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	6,875	196,330	SH		SOLE		196,330	0	0
GLOBAL PMTS INC	COM	37940X102	3,027	16,143	SH		SOLE		16,143	0	0
GLOBAL X FDS	GLOBAL X COPPER	37954Y830	503	13,550	SH		SOLE		13,550	0	0
GLOBUS MED INC	CL A	379577208	2,714	35,000	SH		SOLE		35,000	0	0
GODADDY INC	CL A	380237107	3,571	41,063	SH		SOLE		41,063	0	0
GOLD FIELDS LTD	SPONSORED ADR	38059T106	196	22,021	SH		SOLE		22,021	0	0
GOLDMAN SACHS GROUP INC	COM	38141G104	5,516	14,535	SH		SOLE		14,535	0	0
GOODYEAR TIRE & RUBR CO	COM	382550101	223	13,031	SH		SOLE		13,031	0	0
GRACE W R & CO DEL NEW	COM	38388F108	22,517	325,773	SH		SOLE		325,773	0	0
GRAINGER W W INC	COM	384802104	915	800	PRN		SOLE		800	0	0
GRAINGER W W INC	COM	384802104	6,117	13,966	SH		SOLE		13,966	0	0
GUARDANT HEALTH INC	COM	40131M109	1	5	SH		OTR	1	0	0	5
GUARDANT HEALTH INC	COM	40131M109	12,132	97,691	SH		SOLE		97,691	0	0
HAIN CELESTIAL GROUP INC	COM	405217100	3,213	80,083	SH		SOLE		80,083	0	0
HALLIBURTON CO	COM	406216101	5,988	259,002	SH		SOLE		259,002	0	0
HALOZYME THERAPEUTICS INC	COM	40637H109	1	13	SH		OTR	1	0	0	13
HALOZYME THERAPEUTICS INC	COM	40637H109	24,926	548,917	SH		SOLE		548,917	0	0
HANNON ARMSTRONG SUST INFR C	COM	41068X100	23,438	417,425	SH		SOLE		417,425	0	0
HANNON ARMSTRONG SUST INFR C	COM	41068X100	3	46	SH		OTR	1	0	0	46
HARPOON THERAPEUTICS INC	COM	41358P106	6,789	489,481	SH		SOLE		489,481	0	0
HARPOON THERAPEUTICS INC	COM	41358P106	0	33	SH		OTR	1	0	0	33
HARTFORD FINL SVCS GROUP INC	COM	416515104	2,222	35,848	SH		SOLE		35,848	0	0
HASBRO INC	COM	418056107	8,089	85,582	SH		SOLE		85,582	0	0
HCA HEALTHCARE INC	COM	40412C101	6,442	31,158	SH		SOLE		31,158	0	0
HDFC BANK LTD	SPONSORED ADS	40415F101	2,669	36,500	SH		SOLE		36,500	0	0
HEADHUNTER GROUP PLC	SPONSORED ADS	42207L106	5,457	128,800	SH		SOLE		128,800	0	0
HEALTHPEAK PROPERTIES INC	COM	42250P103	7,805	234,461	SH		SOLE		234,461	0	0
HEICO CORP NEW	CL A	422806208	1,121	9,030	SH		SOLE		9,030	0	0
HENRY JACK & ASSOC INC	COM	426281101	7,699	47,084	SH		SOLE		47,084	0	0
HENRY SCHEIN INC	COM	806407102	295	3,981	SH		SOLE		3,981	0	0
HERON THERAPEUTICS INC	COM	427746102	11,773	758,570	SH		SOLE		758,570	0	0
HERSHEY CO	COM	427866108	5,558	31,911	SH		SOLE		31,911	0	0
HERSHEY CO	COM	427866108	4	22	SH		OTR	1	0	0	22
HESS CORP	COM	42809H107	1,858	21,282	SH		SOLE		21,282	0	0
HEWLETT PACKARD ENTERPRISE C	COM	42824C109	2,006	137,579	SH		SOLE		137,579	0	0
HILTON WORLDWIDE HLDGS INC	COM	43300A203	18,864	156,388	SH		SOLE		156,388	0	0
HOLOGIC INC	COM	436440101	26,432	396,160	SH		SOLE		396,160	0	0
HOLOGIC INC	COM	436440101	2	23	SH		OTR	1	0	0	23
HOME DEPOT INC	COM	437076102	77,077	241,705	SH		SOLE		241,705	0	0
HOME DEPOT INC	COM	437076102	5	17	SH		OTR	1	0	0	17
HONEYWELL INTL INC	COM	438516106	3,940	17,963	SH		SOLE		17,963	0	0
HORMEL FOODS CORP	COM	440452100	1,395	29,217	SH		SOLE		29,217	0	0
HOST HOTELS & RESORTS INC	COM	44107P104	1,180	69,074	SH		SOLE		69,074	0	0
HOWMET AEROSPACE INC	COM	443201108	861	24,980	SH		SOLE		24,980	0	0
HP INC	COM	40434L105	19,898	659,089	SH		SOLE		659,089	0	0
HP INC	COM	40434L105	2	61	SH		OTR	1	0	0	61
HUAZHU GROUP LTD	NOTE 0.375%11/0	16949NAC3	763	600	PRN		SOLE		600	0	0
HUBSPOT INC	COM	443573100	3,425	5,878	SH		SOLE		5,878	0	0
HUMANA INC	COM	444859102	5,591	12,629	SH		SOLE		12,629	0	0
HUNTINGTON BANCSHARES INC	COM	446150104	10,585	741,771	SH		SOLE		741,771	0	0
HUNTINGTON INGALLS INDS INC	COM	446413106	405	1,921	SH		SOLE		1,921	0	0
ICAD INC	COM NEW	44934S206	300	17,332	SH		SOLE		17,332	0	0
ICICI BANK LIMITED	ADR	45104G104	17,123	1,001,321	SH		SOLE		1,001,321	0	0
IDEX CORP	COM	45167R104	8,831	40,134	SH		SOLE		40,134	0	0
IDEXX LABS INC	COM	45168D104	31,531	49,926	SH		SOLE		49,926	0	0
IGM BIOSCIENCES INC	COM	449585108	10,152	122,024	SH		SOLE		122,024	0	0
IGM BIOSCIENCES INC	COM	449585108	0	5	SH		OTR	1	0	0	5
IHS MARKIT LTD	SHS	G47567105	31,154	276,529	SH		SOLE		276,529	0	0
ILLINOIS TOOL WKS INC	COM	452308109	25,760	115,227	SH		SOLE		115,227	0	0
ILLUMINA INC	COM	452327109	1	2	SH		OTR	1	0	0	2
ILLUMINA INC	COM	452327109	92,883	196,283	SH		SOLE		196,283	0	0
ILLUMINA INC	NOTE 8/1	452327AK5	3,697	2,900	PRN		SOLE		2,900	0	0
IMMUNOGEN INC	COM	45253H101	16,220	2,461,363	SH		SOLE		2,461,363	0	0
IMMUNOGEN INC	COM	45253H101	1	96	SH		OTR	1	0	0	96
INCYTE CORP	COM	45337C102	56,525	671,875	SH		SOLE		671,875	0	0
INCYTE CORP	COM	45337C102	2	19	SH		OTR	1	0	0	19
INFOSYS LTD	SPONSORED ADR	456788108	7,069	333,594	SH		SOLE		333,594	0	0
INGERSOLL RAND INC	COM	45687V106	1,599	32,769	SH		SOLE		32,769	0	0
INGREDION INC	COM	457187102	264	2,921	SH		SOLE		2,921	0	0
INSMED INC	COM PAR $.01	457669307	14,379	505,241	SH		SOLE		505,241	0	0
INSMED INC	NOTE 1.750% 1/1	457669AA7	317	300	PRN		SOLE		300	0	0
INSULET CORP	COM	45784P101	1,123	4,092	SH		SOLE		4,092	0	0
INSULET CORP	NOTE 0.375% 9/0	45784PAK7	681	500	PRN		SOLE		500	0	0
INTEL CORP	COM	458140100	4	63	SH		OTR	1	0	0	63
INTEL CORP	COM	458140100	17,562	312,817	SH		SOLE		312,817	0	0
INTELLIA THERAPEUTICS INC	COM	45826J105	16,373	101,127	SH		SOLE		101,127	0	0
INTERCONTINENTAL EXCHANGE IN	COM	45866F104	9,124	76,862	SH		SOLE		76,862	0	0
INTERNATIONAL BUSINESS MACHS	COM	459200101	16,836	114,852	SH		SOLE		114,852	0	0
INTERNATIONAL BUSINESS MACHS	COM	459200101	4	27	SH		OTR	1	0	0	27
INTERNATIONAL FLAVORS&FRAGRA	COM	459506101	3,912	26,183	SH		SOLE		26,183	0	0
INTERNATIONAL PAPER CO	COM	460146103	1,640	26,742	SH		SOLE		26,742	0	0
INTERPUBLIC GROUP COS INC	COM	460690100	21,321	656,238	SH		SOLE		656,238	0	0
INTRA-CELLULAR THERAPIES INC	COM	46116X101	13,041	319,487	SH		SOLE		319,487	0	0
INTUIT	COM	461202103	15,137	30,881	SH		SOLE		30,881	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	42,217	45,906	SH		SOLE		45,906	0	0
INVESCO EXCHANGE TRADED FD T	WILDERHIL CLAN	46137V134	431	4,620	SH		SOLE		4,620	0	0
INVITATION HOMES INC	COM	46187W107	961	25,784	SH		SOLE		25,784	0	0
IONIS PHARMACEUTICALS INC	COM	462222100	22,042	552,566	SH		SOLE		552,566	0	0
IOVANCE BIOTHERAPEUTICS INC	COM	462260100	26,551	1,020,392	SH		SOLE		1,020,392	0	0
IOVANCE BIOTHERAPEUTICS INC	COM	462260100	1	34	SH		OTR	1	0	0	34
IQIYI INC	NOTE 3.750%12/0	46267XAB4	1,017	1,000	PRN		SOLE		1,000	0	0
IQVIA HLDGS INC	COM	46266C105	2	10	SH		OTR	1	0	0	10
IQVIA HLDGS INC	COM	46266C105	48,869	201,670	SH		SOLE		201,670	0	0
IRON MTN INC NEW	COM	46284V101	1,238	29,249	SH		SOLE		29,249	0	0
ISHARES INC	MSCI CDA ETF	464286509	4,223	113,314	SH		SOLE		113,314	0	0
ISHARES TR	GL CLEAN ENE ETF	464288224	497	21,200	SH		SOLE		21,200	0	0
ISHARES TR	ISHARES SEMICDTR	464287523	668	1,470	SH		SOLE		1,470	0	0
ISHARES TR	U.S. MED DVC ETF	464288810	249	690	SH		SOLE		690	0	0
ISORAY INC	COM	46489V104	28	34,883	SH		SOLE		34,883	0	0
ITAU UNIBANCO HLDG S A	SPON ADR REP PFD	465562106	924	153,665	SH		SOLE		153,665	0	0
ITEOS THERAPEUTICS INC	COM	46565G104	12,950	504,859	SH		SOLE		504,859	0	0
ITEOS THERAPEUTICS INC	COM	46565G104	1	31	SH		OTR	1	0	0	31
IVERIC BIO INC	COM	46583P102	4,263	675,575	SH		SOLE		675,575	0	0
JAZZ INVESTMENTS I LTD	NOTE 1.500% 8/1	472145AD3	2,217	2,000	PRN		SOLE		2,000	0	0
JAZZ INVESTMENTS I LTD	NOTE 2.000% 6/1	472145AF8	801	600	PRN		SOLE		600	0	0
JBG SMITH PPTYS	COM	46590V100	4,626	146,796	SH		SOLE		146,796	0	0
JD.COM INC	SPON ADR CL A	47215P106	33,573	420,659	SH		SOLE		420,659	0	0
JOHNSON & JOHNSON	COM	478160104	8	46	SH		OTR	1	0	0	46
JOHNSON & JOHNSON	COM	478160104	106,282	645,148	SH		SOLE		645,148	0	0
JOUNCE THERAPEUTICS INC	COM	481116101	0	16	SH		OTR	1	0	0	16
JOUNCE THERAPEUTICS INC	COM	481116101	2,294	337,382	SH		SOLE		337,382	0	0
JOYY INC	NOTE 0.750% 6/1	98426TAD8	506	500	PRN		SOLE		500	0	0
JPMORGAN CHASE & CO	COM	46625H100	47,481	305,267	SH		SOLE		305,267	0	0
KANSAS CITY SOUTHERN	COM NEW	485170302	12,747	44,985	SH		SOLE		44,985	0	0
KARUNA THERAPEUTICS INC	COM	48576A100	6,241	54,750	SH		SOLE		54,750	0	0
KARYOPHARM THERAPEUTICS INC	COM	48576U106	0	44	SH		OTR	1	0	0	44
KARYOPHARM THERAPEUTICS INC	COM	48576U106	7,406	717,624	SH		SOLE		717,624	0	0
KELLOGG CO	COM	487836108	2	28	SH		OTR	1	0	0	28
KELLOGG CO	COM	487836108	2,076	32,272	SH		SOLE		32,272	0	0
KEROS THERAPEUTICS INC	COM	492327101	4,307	101,409	SH		SOLE		101,409	0	0
KEURIG DR PEPPER INC	COM	49271V100	1	31	SH		OTR	1	0	0	31
KEURIG DR PEPPER INC	COM	49271V100	1,819	51,624	SH		SOLE		51,624	0	0
KEYCORP	COM	493267108	1	70	SH		OTR	1	0	0	70
KEYCORP	COM	493267108	14,044	680,092	SH		SOLE		680,092	0	0
KEYSIGHT TECHNOLOGIES INC	COM	49338L103	31,622	204,795	SH		SOLE		204,795	0	0
KIMBERLY-CLARK CORP	COM	494368103	4,927	36,829	SH		SOLE		36,829	0	0
KIMCO RLTY CORP	COM	49446R109	227	10,900	SH		SOLE		10,900	0	0
KINDER MORGAN INC DEL	COM	49456B101	19,684	1,079,768	SH		SOLE		1,079,768	0	0
KINROSS GOLD CORP	COM	496902404	310	48,799	SH		SOLE		48,799	0	0
KKR & CO INC	COM	48251W104	2,889	48,774	SH		SOLE		48,774	0	0
KLA CORP	COM NEW	482480100	14,160	43,674	SH		SOLE		43,674	0	0
KNOLL INC	COM NEW	498904200	4,798	184,616	SH		SOLE		184,616	0	0
KODIAK SCIENCES INC	COM	50015M109	3,086	33,186	SH		SOLE		33,186	0	0
KRAFT HEINZ CO	COM	500754106	2,678	65,659	SH		SOLE		65,659	0	0
KROGER CO	COM	501044101	17,599	459,397	SH		SOLE		459,397	0	0
KROGER CO	COM	501044101	3	77	SH		OTR	1	0	0	77
KULICKE & SOFFA INDS INC	COM	501242101	4,126	67,421	SH		SOLE		67,421	0	0
KURA ONCOLOGY INC	COM	50127T109	19,731	946,321	SH		SOLE		946,321	0	0
KURA ONCOLOGY INC	COM	50127T109	1	36	SH		OTR	1	0	0	36
KYMERA THERAPEUTICS INC	COM	501575104	1	17	SH		OTR	1	0	0	17
KYMERA THERAPEUTICS INC	COM	501575104	19,932	410,974	SH		SOLE		410,974	0	0
L BRANDS INC	COM	501797104	1,067	14,813	SH		SOLE		14,813	0	0
LABORATORY CORP AMER HLDGS	COM NEW	50540R409	12,453	45,145	SH		SOLE		45,145	0	0
LAM RESEARCH CORP	COM	512807108	1,157	1,000	PRN		SOLE		1,000	0	0
LAM RESEARCH CORP	COM	512807108	29,857	45,884	SH		SOLE		45,884	0	0
LAMB WESTON HLDGS INC	COM	513272104	924	11,455	SH		SOLE		11,455	0	0
LAS VEGAS SANDS CORP	COM	517834107	1,041	19,766	SH		SOLE		19,766	0	0
LAUDER ESTEE COS INC	CL A	518439104	51,065	160,540	SH		SOLE		160,540	0	0
LAUDER ESTEE COS INC	CL A	518439104	1	2	SH		OTR	1	0	0	2
LEMONADE INC	COM	52567D107	602	5,500	SH		SOLE		5,500	0	0
LENNAR CORP	CL A	526057104	1,490	15,000	SH		SOLE		15,000	0	0
LENNOX INTL INC	COM	526107107	3,234	9,218	SH		SOLE		9,218	0	0
LI AUTO INC	SPONSORED ADS	50202M102	226	6,473	SH		SOLE		6,473	0	0
LIBERTY BROADBAND CORP	COM SER C	530307305	1,464	8,432	SH		SOLE		8,432	0	0
LIBERTY MEDIA CORP DEL	COM C SIRIUSXM	531229607	771	16,612	SH		SOLE		16,612	0	0
LILLY ELI & CO	COM	532457108	27,953	121,791	SH		SOLE		121,791	0	0
LINCOLN NATL CORP IND	COM	534187109	1,125	17,900	SH		SOLE		17,900	0	0
LINDE PLC	SHS	G5494J103	1	5	SH		OTR	1	0	0	5
LITHIUM AMERS CORP NEW	COM NEW	53680Q207	630	42,463	SH		SOLE		42,463	0	0
LIVE NATION ENTERTAINMENT IN	COM	538034109	855	9,760	SH		SOLE		9,760	0	0
LKQ CORP	COM	501889208	2,070	42,048	SH		SOLE		42,048	0	0
LOEWS CORP	COM	540424108	2,425	44,378	SH		SOLE		44,378	0	0
LOUISIANA PAC CORP	COM	546347105	7,762	128,748	SH		SOLE		128,748	0	0
LOWES COS INC	COM	548661107	53,415	275,377	SH		SOLE		275,377	0	0
LULULEMON ATHLETICA INC	COM	550021109	18,363	50,313	SH		SOLE		50,313	0	0
LUMEN TECHNOLOGIES INC	COM	550241103	900	66,231	SH		SOLE		66,231	0	0
LUMENTUM HLDGS INC	NOTE 0.500%12/1	55024UAD1	1,088	1,000	PRN		SOLE		1,000	0	0
LUMINEX CORP DEL	COM	55027E102	17,610	478,532	SH		SOLE		478,532	0	0
LYDALL INC	COM	550819106	6,003	99,198	SH		SOLE		99,198	0	0
LYFT INC	CL A COM	55087P104	591	9,772	SH		SOLE		9,772	0	0
M & T BK CORP	COM	55261F104	1,450	9,982	SH		SOLE		9,982	0	0
MACROGENICS INC	COM	556099109	16,344	608,499	SH		SOLE		608,499	0	0
MACROGENICS INC	COM	556099109	1	24	SH		OTR	1	0	0	24
MAGELLAN HEALTH INC	COM NEW	559079207	18,258	193,817	SH		SOLE		193,817	0	0
MAGNA INTL INC	COM	559222401	1,295	13,970	SH		SOLE		13,970	0	0
MANNKIND CORP	COM NEW	56400P706	63	11,500	SH		SOLE		11,500	0	0
MANPOWERGROUP INC WIS	COM	56418H100	9,242	77,722	SH		SOLE		77,722	0	0
MANULIFE FINL CORP	COM	56501R106	3,900	197,927	SH		SOLE		197,927	0	0
MARATHON OIL CORP	COM	565849106	960	70,479	SH		SOLE		70,479	0	0
MARATHON PETE CORP	COM	56585A102	2,128	35,217	SH		SOLE		35,217	0	0
MARKEL CORP	COM	570535104	822	693	SH		SOLE		693	0	0
MARKETAXESS HLDGS INC	COM	57060D108	1,009	2,176	SH		SOLE		2,176	0	0
MARRIOTT INTL INC NEW	CL A	571903202	8,146	59,667	SH		SOLE		59,667	0	0
MARSH & MCLENNAN COS INC	COM	571748102	5,368	38,158	SH		SOLE		38,158	0	0
MARSH & MCLENNAN COS INC	COM	571748102	1	8	SH		OTR	1	0	0	8
MARTIN MARIETTA MATLS INC	COM	573284106	3,945	11,213	SH		SOLE		11,213	0	0
MARVELL TECHNOLOGY INC	COM	573874104	2,792	47,862	SH		SOLE		47,862	0	0
MASCO CORP	COM	574599106	2	36	SH		OTR	1	0	0	36
MASCO CORP	COM	574599106	17,014	288,818	SH		SOLE		288,818	0	0
MASIMO CORP	COM	574795100	5,113	21,090	SH		SOLE		21,090	0	0
MASTEC INC	COM	576323109	2	19	SH		OTR	1	0	0	19
MASTEC INC	COM	576323109	18,836	177,529	SH		SOLE		177,529	0	0
MASTERCARD INCORPORATED	CL A	57636Q104	53,465	146,444	SH		SOLE		146,444	0	0
MASTERCARD INCORPORATED	CL A	57636Q104	1	3	SH		OTR	1	0	0	3
MATCH GROUP INC NEW	COM	57667L107	2,102	13,035	SH		SOLE		13,035	0	0
MAXIM INTEGRATED PRODS INC	COM	57772K101	48,529	460,606	SH		SOLE		460,606	0	0
MCCORMICK & CO INC	COM NON VTG	579780206	11,570	130,997	SH		SOLE		130,997	0	0
MCCORMICK & CO INC	COM NON VTG	579780206	1	8	SH		OTR	1	0	0	8
MCDONALDS CORP	COM	580135101	55,882	241,922	SH		SOLE		241,922	0	0
MCDONALDS CORP	COM	580135101	2	7	SH		OTR	1	0	0	7
MCKESSON CORP	COM	58155Q103	1,850	9,676	SH		SOLE		9,676	0	0
MEDTRONIC PLC	SHS	G5960L103	5	37	SH		OTR	1	0	0	37
MERCADOLIBRE INC	COM	58733R102	33,706	21,637	SH		SOLE		21,637	0	0
MERCK & CO INC	COM	58933Y105	18	226	SH		OTR	1	0	0	226
MERCK & CO INC	COM	58933Y105	335,817	4,318,081	SH		SOLE		4,318,081	0	0
MERIDIAN BANCORP INC MD	COM	58958U103	305	14,912	SH		SOLE		14,912	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	1	79	SH		OTR	1	0	0	79
MERSANA THERAPEUTICS INC	COM	59045L106	26,791	1,972,816	SH		SOLE		1,972,816	0	0
MERUS N V	COM	N5749R100	1	44	SH		OTR	1	0	0	44
MESA LABS INC	COM	59064R109	1,789	6,597	SH		SOLE		6,597	0	0
METLIFE INC	COM	59156R108	8,178	136,638	SH		SOLE		136,638	0	0
METLIFE INC	COM	59156R108	3	50	SH		OTR	1	0	0	50
METTLER TOLEDO INTERNATIONAL	COM	592688105	25,499	18,406	SH		SOLE		18,406	0	0
MGM RESORTS INTERNATIONAL	COM	552953101	1,025	24,030	SH		SOLE		24,030	0	0
MICROCHIP TECHNOLOGY INC.	COM	595017104	2,398	16,012	SH		SOLE		16,012	0	0
MICRON TECHNOLOGY INC	COM	595112103	6,229	73,297	SH		SOLE		73,297	0	0
MICRON TECHNOLOGY INC	COM	595112103	2	23	SH		OTR	1	0	0	23
MICROSOFT CORP	COM	594918104	673,455	2,485,992	SH		SOLE		2,485,992	0	0
MICROSOFT CORP	COM	594918104	25	92	SH		OTR	1	0	0	92
MID-AMER APT CMNTYS INC	COM	59522J103	4,897	29,075	SH		SOLE		29,075	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	55,822	345,583	SH		SOLE		345,583	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	2	13	SH		OTR	1	0	0	13
MOBILE TELESYSTEMS PJSC	SPONSORED ADR	607409109	5,223	564,000	SH		SOLE		564,000	0	0
MODERNA INC	COM	60770K107	72,142	307,014	SH		SOLE		307,014	0	0
MOHAWK INDS INC	COM	608190104	1,484	7,720	SH		SOLE		7,720	0	0
MOLINA HEALTHCARE INC	COM	60855R100	674	2,662	SH		SOLE		2,662	0	0
MOLSON COORS BEVERAGE CO	CL B	60871R209	759	14,134	SH		SOLE		14,134	0	0
MONDELEZ INTL INC	CL A	609207105	9,302	148,972	SH		SOLE		148,972	0	0
MONGODB INC	CL A	60937P106	1,578	4,365	SH		SOLE		4,365	0	0
MONGODB INC	NOTE 0.250% 1/1	60937PAD8	728	400	PRN		SOLE		400	0	0
MONSTER BEVERAGE CORP NEW	COM	61174X109	3,137	34,343	SH		SOLE		34,343	0	0
MOODYS CORP	COM	615369105	477	500	PRN		SOLE		500	0	0
MOODYS CORP	COM	615369105	11,113	30,667	SH		SOLE		30,667	0	0
MORGAN STANLEY	COM NEW	617446448	20,391	222,388	SH		SOLE		222,388	0	0
MORGAN STANLEY	COM NEW	617446448	4	43	SH		OTR	1	0	0	43
MORGAN STANLEY	COM NEW	617446448	723	500	PRN		SOLE		500	0	0
MORPHOSYS AG	SPONSORED ADS	617760202	5,174	268,778	SH		SOLE		268,778	0	0
MORPHOSYS AG	SPONSORED ADS	617760202	1	57	SH		OTR	1	0	0	57
MOSAIC CO NEW	COM	61945C103	1,684	52,779	SH		SOLE		52,779	0	0
MOTOROLA SOLUTIONS INC	COM NEW	620076307	2,405	11,092	SH		SOLE		11,092	0	0
MR COOPER GROUP INC	COM	62482R107	664	20,096	SH		SOLE		20,096	0	0
MSCI INC	COM	55354G100	2,430	4,558	SH		SOLE		4,558	0	0
MYMD PHARMACEUTICALS INC	COM	62856X102	114	18,073	SH		SOLE		18,073	0	0
NATIONAL FUEL GAS CO	COM	636180101	561	10,738	SH		SOLE		10,738	0	0
NATURA &CO HLDG S A	ADS	63884N108	234	10,298	SH		SOLE		10,298	0	0
NAUTILUS BIOTECHNOLOGY INC	COM	63909J108	1,566	155,000	SH		SOLE		155,000	0	0
NEOGENOMICS INC	COM NEW	64049M209	8,461	187,319	SH		SOLE		187,319	0	0
NEOGENOMICS INC	COM NEW	64049M209	1	13	SH		OTR	1	0	0	13
NEOLEUKIN THERAPEUTICS INC	COM	64049K104	0	35	SH		OTR	1	0	0	35
NEOLEUKIN THERAPEUTICS INC	COM	64049K104	4,726	511,978	SH		SOLE		511,978	0	0
NETAPP INC	COM	64110D104	1,054	12,887	SH		SOLE		12,887	0	0
NETEASE INC	SPONSORED ADS	64110W102	4,397	38,150	SH		SOLE		38,150	0	0
NETFLIX INC	COM	64110L106	22,896	43,346	SH		SOLE		43,346	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	7,931	81,493	SH		SOLE		81,493	0	0
NEW ORIENTAL ED & TECHNOLOGY	SPON ADR	647581107	6,869	838,660	SH		SOLE		838,660	0	0
NEWELL BRANDS INC	COM	651229106	2,370	86,289	SH		SOLE		86,289	0	0
NEWMONT CORP	COM	651639106	7,946	125,371	SH		SOLE		125,371	0	0
NEWMONT CORP	COM	651639106	2	26	SH		OTR	1	0	0	26
NEWS CORP NEW	CL A	65249B109	611	23,724	SH		SOLE		23,724	0	0
NEXTERA ENERGY INC	COM	65339F101	38,856	530,240	SH		SOLE		530,240	0	0
NEXTERA ENERGY PARTNERS LP	COM UNIT PART IN	65341B106	33,701	441,347	SH		SOLE		441,347	0	0
NEXTERA ENERGY PARTNERS LP	COM UNIT PART IN	65341B106	3	40	SH		OTR	1	0	0	40
NGM BIOPHARMACEUTICALS INC	COM	62921N105	11,123	564,059	SH		SOLE		564,059	0	0
NIKE INC	CL B	654106103	5	31	SH		OTR	1	0	0	31
NIKE INC	CL B	654106103	99,816	646,097	SH		SOLE		646,097	0	0
NIO INC	SPON ADS	62914V106	43,513	817,916	SH		SOLE		817,916	0	0
NKARTA INC	COM	65487U108	0	4	SH		OTR	1	0	0	4
NOMAD FOODS LTD	USD ORD SHS	G6564A105	3,167	112,044	SH		SOLE		112,044	0	0
NORFOLK SOUTHN CORP	COM	655844108	16,417	61,855	SH		SOLE		61,855	0	0
NORTHERN TR CORP	COM	665859104	5,529	47,821	SH		SOLE		47,821	0	0
NORTONLIFELOCK INC	COM	668771108	1,163	42,729	SH		SOLE		42,729	0	0
NOVAVAX INC	COM NEW	670002401	26,183	123,323	SH		SOLE		123,323	0	0
NOVOCURE LTD	ORD SHS	G6674U108	1	3	SH		OTR	1	0	0	3
NOVO-NORDISK A S	ADR	670100205	2	28	SH		OTR	1	0	0	28
NU SKIN ENTERPRISES INC	CL A	67018T105	3,618	63,871	SH		SOLE		63,871	0	0
NUANCE COMMUNICATIONS INC	COM	67020Y100	22,790	418,618	SH		SOLE		418,618	0	0
NUCOR CORP	COM	670346105	2,257	23,526	SH		SOLE		23,526	0	0
NURIX THERAPEUTICS INC	COM	67080M103	13,458	507,287	SH		SOLE		507,287	0	0
NURIX THERAPEUTICS INC	COM	67080M103	0	16	SH		OTR	1	0	0	16
NUTRIEN LTD	COM	67077M108	839	13,835	SH		SOLE		13,835	0	0
NVIDIA CORPORATION	COM	67066G104	126,973	158,696	SH		SOLE		158,696	0	0
NVR INC	COM	62944T105	1,373	276	SH		SOLE		276	0	0
OCCIDENTAL PETE CORP	COM	674599105	1,577	50,421	SH		SOLE		50,421	0	0
OKTA INC	CL A	679295105	8,262	33,765	SH		SOLE		33,765	0	0
OKTA INC	NOTE 0.375% 6/1	679295AF2	1,621	1,300	PRN		SOLE		1,300	0	0
OLD DOMINION FREIGHT LINE IN	COM	679580100	4,237	16,694	SH		SOLE		16,694	0	0
OLEMA PHARMACEUTICALS INC	COM	68062P106	9,780	349,551	SH		SOLE		349,551	0	0
OLEMA PHARMACEUTICALS INC	COM	68062P106	1	21	SH		OTR	1	0	0	21
OMNICOM GROUP INC	COM	681919106	2	24	SH		OTR	1	0	0	24
OMNICOM GROUP INC	COM	681919106	1,908	23,851	SH		SOLE		23,851	0	0
ON SEMICONDUCTOR CORP	COM	682189105	3	79	SH		OTR	1	0	0	79
ON SEMICONDUCTOR CORP	COM	682189105	58,269	1,522,186	SH		SOLE		1,522,186	0	0
ONEOK INC NEW	COM	682680103	2,308	41,489	SH		SOLE		41,489	0	0
ORACLE CORP	COM	68389X105	13,472	173,069	SH		SOLE		173,069	0	0
ORBCOMM INC	COM	68555P100	9,456	841,269	SH		SOLE		841,269	0	0
OREILLY AUTOMOTIVE INC	COM	67103H107	3,817	6,742	SH		SOLE		6,742	0	0
ORGANON & CO	COMMON STOCK	68622V106	1,552	51,274	SH		SOLE		51,274	0	0
ORMAT TECHNOLOGIES INC	COM	686688102	1,235	17,755	SH		SOLE		17,755	0	0
ORTHOPEDIATRICS CORP	COM	68752L100	4,193	66,369	SH		SOLE		66,369	0	0
OTIS WORLDWIDE CORP	COM	68902V107	23,044	281,820	SH		SOLE		281,820	0	0
OTIS WORLDWIDE CORP	COM	68902V107	1	18	SH		OTR	1	0	0	18
OUTSET MED INC	COM	690145107	4,376	87,555	SH		SOLE		87,555	0	0
OWENS CORNING NEW	COM	690742101	2	23	SH		OTR	1	0	0	23
OWENS CORNING NEW	COM	690742101	1,356	1,300	PRN		SOLE		1,300	0	0
OWENS CORNING NEW	COM	690742101	47,672	486,950	SH		SOLE		486,950	0	0
PACCAR INC	COM	693718108	3,829	42,900	SH		SOLE		42,900	0	0
PACIFIC BIOSCIENCES CALIF IN	COM	69404D108	9,807	280,431	SH		SOLE		280,431	0	0
PACKAGING CORP AMER	COM	695156109	821	6,059	SH		SOLE		6,059	0	0
PAGSEGURO DIGITAL LTD	COM CL A	G68707101	10,723	191,750	SH		SOLE		191,750	0	0
PALO ALTO NETWORKS INC	COM	697435105	3	7	SH		OTR	1	0	0	7
PALO ALTO NETWORKS INC	COM	697435105	78,848	212,499	SH		SOLE		212,499	0	0
PALO ALTO NETWORKS INC	NOTE 0.375% 6/0	697435AF2	3,251	1,390,000	PRN		SOLE		1,390,000	0	0
PALO ALTO NETWORKS INC	NOTE 0.750% 7/0	697435AD7	2,190	1,500	PRN		SOLE		1,500	0	0
PAN AMERN SILVER CORP	COM	697900108	2,560	89,600	SH		SOLE		89,600	0	0
PARKER-HANNIFIN CORP	COM	701094104	22,297	72,603	SH		SOLE		72,603	0	0
PAYCHEX INC	COM	704326107	2,227	20,754	SH		SOLE		20,754	0	0
PAYCOM SOFTWARE INC	COM	70432V102	1,148	3,158	SH		SOLE		3,158	0	0
PAYPAL HLDGS INC	COM	70450Y103	109,176	374,557	SH		SOLE		374,557	0	0
PELOTON INTERACTIVE INC	CL A COM	70614W100	5,557	44,807	SH		SOLE		44,807	0	0
PEMBINA PIPELINE CORP	COM	706327103	481	15,130	SH		SOLE		15,130	0	0
PENTAIR PLC	SHS	G7S00T104	1	17	SH		OTR	1	0	0	17
PEOPLES UNITED FINANCIAL INC	COM	712704105	208	12,163	SH		SOLE		12,163	0	0
PEPSICO INC	COM	713448108	4	29	SH		OTR	1	0	0	29
PEPSICO INC	COM	713448108	26,893	181,504	SH		SOLE		181,504	0	0
PERKINELMER INC	COM	714046109	4,405	28,531	SH		SOLE		28,531	0	0
PERSONALIS INC	COM	71535D106	8,143	321,846	SH		SOLE		321,846	0	0
PERSONALIS INC	COM	71535D106	1	21	SH		OTR	1	0	0	21
PETROLEO BRASILEIRO SA PETRO	SPONSORED ADR	71654V408	308	25,150	SH		SOLE		25,150	0	0
PFIZER INC	COM	717081103	4,888	124,825	SH		SOLE		124,825	0	0
PHASEBIO PHARMACEUTICALS INC	COM	717224109	2,304	619,434	SH		SOLE		619,434	0	0
PHILLIPS 66	COM	718546104	3,340	38,913	SH		SOLE		38,913	0	0
PIERIS PHARMACEUTICALS INC	COM	720795103	4,067	1,061,834	SH		SOLE		1,061,834	0	0
PINDUODUO INC	NOTE 12/0	722304AC6	1,450	1,400	PRN		SOLE		1,400	0	0
PINDUODUO INC	SPONSORED ADS	722304102	43,027	338,743	SH		SOLE		338,743	0	0
PINTEREST INC	CL A	72352L106	2,462	31,181	SH		SOLE		31,181	0	0
PIONEER NAT RES CO	COM	723787107	1,934	11,898	SH		SOLE		11,898	0	0
PLANET FITNESS INC	CL A	72703H101	5,818	77,320	SH		SOLE		77,320	0	0
PLUG POWER INC	COM NEW	72919P202	1,214	35,495	SH		SOLE		35,495	0	0
PNC FINL SVCS GROUP INC	COM	693475105	20,718	108,608	SH		SOLE		108,608	0	0
POOL CORP	COM	73278L105	255	556	SH		SOLE		556	0	0
POTLATCHDELTIC CORPORATION	COM	737630103	1,724	32,428	SH		SOLE		32,428	0	0
POWER INTEGRATIONS INC	COM	739276103	22,464	273,757	SH		SOLE		273,757	0	0
POWER INTEGRATIONS INC	COM	739276103	2	30	SH		OTR	1	0	0	30
PPD INC	COM	69355F102	18,296	396,971	SH		SOLE		396,971	0	0
PPG INDS INC	COM	693506107	15,966	94,042	SH		SOLE		94,042	0	0
PRA HEALTH SCIENCES INC	COM	69354M108	14,463	87,515	SH		SOLE		87,515	0	0
PRECISION BIOSCIENCES INC	COM	74019P108	7,927	633,162	SH		SOLE		633,162	0	0
PRICE T ROWE GROUP INC	COM	74144T108	5,867	29,636	SH		SOLE		29,636	0	0
PRICELINE GRP INC	NOTE 0.900% 9/1	741503AX4	19,148	17,522	PRN		SOLE		17,522	0	0
PRINCIPAL FINANCIAL GROUP IN	COM	74251V102	1,800	28,483	SH		SOLE		28,483	0	0
PROCTER AND GAMBLE CO	COM	742718109	7	52	SH		OTR	1	0	0	52
PROCTER AND GAMBLE CO	COM	742718109	117,198	868,581	SH		SOLE		868,581	0	0
PROGRESSIVE CORP	COM	743315103	3,450	35,129	SH		SOLE		35,129	0	0
PROLOGIS INC.	COM	74340W103	31,732	265,477	SH		SOLE		265,477	0	0
PROOFPOINT INC	COM	743424103	17,199	98,981	SH		SOLE		98,981	0	0
PROOFPOINT INC	NOTE 0.250% 8/1	743424AF0	753	600	PRN		SOLE		600	0	0
PROTAGONIST THERAPEUTICS INC	COM	74366E102	3,754	83,646	SH		SOLE		83,646	0	0
PRUDENTIAL FINL INC	COM	744320102	5,774	56,351	SH		SOLE		56,351	0	0
PRUDENTIAL FINL INC	COM	744320102	4	37	SH		OTR	1	0	0	37
PTC INC	COM	69370C100	46,490	329,110	SH		SOLE		329,110	0	0
PTC THERAPEUTICS INC	COM	69366J200	11,556	273,374	SH		SOLE		273,374	0	0
PUBLIC STORAGE	COM	74460D109	2,621	8,716	SH		SOLE		8,716	0	0
PUBLIC SVC ENTERPRISE GRP IN	COM	744573106	2,412	40,380	SH		SOLE		40,380	0	0
PULTE GROUP INC	COM	745867101	1,927	35,316	SH		SOLE		35,316	0	0
QORVO INC	COM	74736K101	24,997	127,763	SH		SOLE		127,763	0	0
QUALCOMM INC	COM	747525103	96,070	672,149	SH		SOLE		672,149	0	0
QUALCOMM INC	COM	747525103	2	14	SH		OTR	1	0	0	14
QUEST DIAGNOSTICS INC	COM	74834L100	9,303	70,495	SH		SOLE		70,495	0	0
RADIUS HEALTH INC	COM NEW	750469207	7,352	403,068	SH		SOLE		403,068	0	0
RADNET INC	COM	750491102	1	20	SH		OTR	1	0	0	20
RADNET INC	COM	750491102	10,417	309,191	SH		SOLE		309,191	0	0
RAYMOND JAMES FINL INC	COM	754730109	3,504	26,978	SH		SOLE		26,978	0	0
REALTY INCOME CORP	COM	756109104	1,613	24,164	SH		SOLE		24,164	0	0
REDHILL BIOPHARMA LTD	SPONSORED ADS	757468103	568	82,523	SH		SOLE		82,523	0	0
REGENERON PHARMACEUTICALS	COM	75886F107	9	17	SH		OTR	1	0	0	17
REGENERON PHARMACEUTICALS	COM	75886F107	296,210	530,329	SH		SOLE		530,329	0	0
REGIONS FINANCIAL CORP NEW	COM	7591EP100	25,920	1,284,435	SH		SOLE		1,284,435	0	0
RELAY THERAPEUTICS INC	COM	75943R102	20,597	562,918	SH		SOLE		562,918	0	0
RELAY THERAPEUTICS INC	COM	75943R102	1	20	SH		OTR	1	0	0	20
RENEWABLE ENERGY GROUP INC	COM NEW	75972A301	1,448	23,235	SH		SOLE		23,235	0	0
REPLIGEN CORP	COM	759916109	6,082	30,470	SH		SOLE		30,470	0	0
REPLIMUNE GROUP INC	COM	76029N106	18,670	485,953	SH		SOLE		485,953	0	0
REPLIMUNE GROUP INC	COM	76029N106	1	35	SH		OTR	1	0	0	35
REPUBLIC SVCS INC	COM	760759100	5	42	SH		OTR	1	0	0	42
REPUBLIC SVCS INC	COM	760759100	831	7,557	SH		SOLE		7,557	0	0
RESMED INC	COM	761152107	4,661	18,907	SH		SOLE		18,907	0	0
RESTAURANT BRANDS INTL INC	COM	76131D103	4,898	75,940	SH		SOLE		75,940	0	0
REVOLUTION MEDICINES INC	COM	76155X100	12,507	394,056	SH		SOLE		394,056	0	0
REVOLUTION MEDICINES INC	COM	76155X100	0	14	SH		OTR	1	0	0	14
RIGEL PHARMACEUTICALS INC	COM NEW	766559603	9,642	2,221,696	SH		SOLE		2,221,696	0	0
RINGCENTRAL INC	CL A	76680R206	1,330	4,577	SH		SOLE		4,577	0	0
RINGCENTRAL INC	NOTE 3/0	76680RAF4	1,658	1,500	PRN		SOLE		1,500	0	0
RIO TINTO PLC	SPONSORED ADR	767204100	2	21	SH		OTR	1	0	0	21
RIOT BLOCKCHAIN INC	COM	767292105	220	5,840	SH		SOLE		5,840	0	0
ROBERT HALF INTL INC	COM	770323103	4,994	56,127	SH		SOLE		56,127	0	0
ROCKWELL AUTOMATION INC	COM	773903109	3	12	SH		OTR	1	0	0	12
ROCKWELL AUTOMATION INC	COM	773903109	65,130	227,711	SH		SOLE		227,711	0	0
ROGERS COMMUNICATIONS INC	CL B	775109200	2,465	46,324	SH		SOLE		46,324	0	0
ROKU INC	COM CL A	77543R102	2,661	5,795	SH		SOLE		5,795	0	0
ROLLINS INC	COM	775711104	1,362	39,835	SH		SOLE		39,835	0	0
ROPER TECHNOLOGIES INC	COM	776696106	4,091	8,701	SH		SOLE		8,701	0	0
ROSS STORES INC	COM	778296103	2,725	21,972	SH		SOLE		21,972	0	0
ROSS STORES INC	COM	778296103	563	500	PRN		SOLE		500	0	0
ROYAL BK CDA	COM	780087102	132,186	1,303,396	SH		SOLE		1,303,396	0	0
ROYAL BK CDA	COM	780087102	5	47	SH		OTR	1	0	0	47
ROYAL DUTCH SHELL PLC	SPONS ADR A	780259206	4	91	SH		OTR	1	0	0	91
S&P GLOBAL INC	COM	78409V104	2	4	SH		OTR	1	0	0	4
S&P GLOBAL INC	COM	78409V104	35,736	87,065	SH		SOLE		87,065	0	0
SAGE THERAPEUTICS INC	COM	78667J108	7,872	138,568	SH		SOLE		138,568	0	0
SAILPOINT TECHNOLOGIES HLDGS	COM	78781P105	37,702	738,233	SH		SOLE		738,233	0	0
SALESFORCE COM INC	COM	79466L302	91,292	373,734	SH		SOLE		373,734	0	0
SALESFORCE COM INC	COM	79466L302	2	9	SH		OTR	1	0	0	9
SAP SE	SPON ADR	803054204	1	10	SH		OTR	1	0	0	10
SBA COMMUNICATIONS CORP NEW	CL A	78410G104	2,428	7,619	SH		SOLE		7,619	0	0
SCHLUMBERGER LTD	COM STK	806857108	16,382	511,775	SH		SOLE		511,775	0	0
SCHWAB CHARLES CORP	COM	808513105	37,763	518,650	SH		SOLE		518,650	0	0
SCHWAB CHARLES CORP	COM	808513105	2	33	SH		OTR	1	0	0	33
SEA LTD	SPONSORD ADS	81141R100	378	1,375	SH		SOLE		1,375	0	0
SEAGEN INC	COM	81181C104	5	29	SH		OTR	1	0	0	29
SEAGEN INC	COM	81181C104	132,901	841,788	SH		SOLE		841,788	0	0
SEER INC	COM CL A	81578P106	1,311	40,000	SH		SOLE		40,000	0	0
SELECT MED HLDGS CORP	COM	81619Q105	2,756	65,206	SH		SOLE		65,206	0	0
SEMPRA ENERGY	COM	816851109	5,048	38,101	SH		SOLE		38,101	0	0
SERVICENOW INC	COM	81762P102	10,942	19,911	SH		SOLE		19,911	0	0
SHAW COMMUNICATIONS INC	CL B CONV	82028K200	318	10,956	SH		SOLE		10,956	0	0
SHERWIN WILLIAMS CO	COM	824348106	22,775	83,594	SH		SOLE		83,594	0	0
SHERWIN WILLIAMS CO	COM	824348106	1	5	SH		OTR	1	0	0	5
SHINHAN FINANCIAL GROUP CO L	SPN ADR RESTRD	824596100	430	12,000	SH		SOLE		12,000	0	0
SHOPIFY INC	CL A	82509L107	2,932	2,003	SH		SOLE		2,003	0	0
SHOPIFY INC	NOTE 0.125%11/0	82509LAA5	1,958	1,500	PRN		SOLE		1,500	0	0
SILICON LABORATORIES INC	COM	826919102	35,457	231,369	SH		SOLE		231,369	0	0
SILICON LABORATORIES INC	NOTE 0.625% 6/1	826919AD4	2,780	2,000	PRN		SOLE		2,000	0	0
SILVERBACK THERAPEUTICS INC	COM	82835W108	0	13	SH		OTR	1	0	0	13
SILVERBACK THERAPEUTICS INC	COM	82835W108	6,071	196,544	SH		SOLE		196,544	0	0
SIMON PPTY GROUP INC NEW	COM	828806109	2,618	20,066	SH		SOLE		20,066	0	0
SIRIUS XM HOLDINGS INC	COM	82968B103	216	32,995	SH		SOLE		32,995	0	0
SIRIUS XM HOLDINGS INC	COM	82968B103	786	750	PRN		SOLE		750	0	0
SKYWORKS SOLUTIONS INC	COM	83088M102	1,684	8,781	SH		SOLE		8,781	0	0
SL GREEN RLTY CORP	COM	78440X804	5,575	69,682	SH		SOLE		69,682	0	0
SLACK TECHNOLOGIES INC	COM CL A	83088V102	26,194	591,282	SH		SOLE		591,282	0	0
SLEEP NUMBER CORP	COM	83125X103	3,118	28,360	SH		SOLE		28,360	0	0
SMITH A O CORP	COM	831865209	2,528	35,080	SH		SOLE		35,080	0	0
SMITH A O CORP	COM	831865209	1	19	SH		OTR	1	0	0	19
SMUCKER J M CO	COM NEW	832696405	12,683	97,889	SH		SOLE		97,889	0	0
SNAP INC	CL A	83304A106	3,610	52,982	SH		SOLE		52,982	0	0
SNAP ON INC	COM	833034101	1,396	6,249	SH		SOLE		6,249	0	0
SNOWFLAKE INC	CL A	833445109	4,265	17,637	SH		SOLE		17,637	0	0
SOCIEDAD QUIMICA Y MINERA DE	SPON ADR SER B	833635105	36,434	769,795	SH		SOLE		769,795	0	0
SOLAREDGE TECHNOLOGIES INC	COM	83417M104	19,544	70,717	SH		SOLE		70,717	0	0
SOLAREDGE TECHNOLOGIES INC	COM	83417M104	3	11	SH		OTR	1	0	0	11
SOLITON INC	COM	834251100	1,524	67,770	SH		SOLE		67,770	0	0
SONY GROUP CORPORATION	SPONSORED ADR	835699307	2,946	30,301	SH		SOLE		30,301	0	0
SONY GROUP CORPORATION	SPONSORED ADR	835699307	4	39	SH		OTR	1	0	0	39
SOUTHERN COPPER CORP	COM	84265V105	21,399	332,700	SH		SOLE		332,700	0	0
SPDR S&P 500 ETF TR	TR UNIT	78462F103	2,946	632,400	SH	Put	SOLE		632,400	0	0
SPLUNK INC	COM	848637104	34,539	238,889	SH		SOLE		238,889	0	0
SPLUNK INC	NOTE 1.125% 6/1	848637AF1	6,471	2,634,000	PRN		SOLE		2,634,000	0	0
SPORTSMANS WHSE HLDGS INC	COM	84920Y106	12,600	709,064	SH		SOLE		709,064	0	0
SPRINGWORKS THERAPEUTICS INC	COM	85205L107	1	9	SH		OTR	1	0	0	9
SPRINGWORKS THERAPEUTICS INC	COM	85205L107	11,605	140,825	SH		SOLE		140,825	0	0
SPROUTS FMRS MKT INC	COM	85208M102	801	32,221	SH		SOLE		32,221	0	0
SQUARE INC	CL A	852234103	6,437	26,404	SH		SOLE		26,404	0	0
STANLEY BLACK & DECKER INC	COM	854502101	1,468	7,159	SH		SOLE		7,159	0	0
STARBUCKS CORP	COM	855244109	2	14	SH		OTR	1	0	0	14
STARBUCKS CORP	COM	855244109	65,233	583,430	SH		SOLE		583,430	0	0
STATE STR CORP	COM	857477103	3,714	45,139	SH		SOLE		45,139	0	0
STEEL DYNAMICS INC	COM	858119100	1,196	20,074	SH		SOLE		20,074	0	0
STRYKER CORPORATION	COM	863667101	42,568	163,895	SH		SOLE		163,895	0	0
STRYKER CORPORATION	COM	863667101	2	8	SH		OTR	1	0	0	8
SUMITOMO MITSUI FINL GROUP I	SPONSORED ADR	86562M209	1	137	SH		OTR	1	0	0	137
SUN CMNTYS INC	COM	866674104	995	5,808	SH		SOLE		5,808	0	0
SUN LIFE FINANCIAL INC.	COM	866796105	1,060	20,532	SH		SOLE		20,532	0	0
SUNCOR ENERGY INC NEW	COM	867224107	775	32,317	SH		SOLE		32,317	0	0
SUNRUN INC	COM	86771W105	665	11,917	SH		SOLE		11,917	0	0
SUTRO BIOPHARMA INC	COM	869367102	6,807	366,183	SH		SOLE		366,183	0	0
SUTRO BIOPHARMA INC	COM	869367102	0	24	SH		OTR	1	0	0	24
SVB FINANCIAL GROUP	COM	78486Q101	1,618	2,907	SH		SOLE		2,907	0	0
SYNCHRONY FINANCIAL	COM	87165B103	26,513	546,442	SH		SOLE		546,442	0	0
SYNOPSYS INC	COM	871607107	30,604	110,970	SH		SOLE		110,970	0	0
SYNOPSYS INC	COM	871607107	3	11	SH		OTR	1	0	0	11
SYROS PHARMACEUTICALS INC	COM	87184Q107	3,184	584,272	SH		SOLE		584,272	0	0
SYSCO CORP	COM	871829107	2,655	34,144	SH		SOLE		34,144	0	0
TAIWAN SEMICONDUCTOR MFG LTD	SPONSORED ADS	874039100	2	19	SH		OTR	1	0	0	19
TAIWAN SEMICONDUCTOR MFG LTD	SPONSORED ADS	874039100	94,802	788,968	SH		SOLE		788,968	0	0
TAKEDA PHARMACEUTICAL CO LTD	SPONSORED ADS	874060205	1	78	SH		OTR	1	0	0	78
TAKE-TWO INTERACTIVE SOFTWAR	COM	874054109	1,744	9,852	SH		SOLE		9,852	0	0
TAL EDUCATION GROUP	SPONSORED ADS	874080104	2,960	117,335	SH		SOLE		117,335	0	0
TALEND S A	ADS	874224207	17,629	268,728	SH		SOLE		268,728	0	0
TANDEM DIABETES CARE INC	COM NEW	875372203	7,167	73,587	SH		SOLE		73,587	0	0
TARGET CORP	COM	87612E106	3,525	3,250	PRN		SOLE		3,250	0	0
TARGET CORP	COM	87612E106	2	9	SH		OTR	1	0	0	9
TARGET CORP	COM	87612E106	29,064	120,228	SH		SOLE		120,228	0	0
TAYLOR MORRISON HOME CORP	COM	87724P106	3,297	124,810	SH		SOLE		124,810	0	0
TC ENERGY CORP	COM	87807B107	1,266	25,558	SH		SOLE		25,558	0	0
TCR2 THERAPEUTICS INC	COM	87808K106	1	42	SH		OTR	1	0	0	42
TCR2 THERAPEUTICS INC	COM	87808K106	15,335	934,509	SH		SOLE		934,509	0	0
TE CONNECTIVITY LTD	REG SHS	H84989104	2	18	SH		OTR	1	0	0	18
TECK RESOURCES LTD	CL B	878742204	767	33,272	SH		SOLE		33,272	0	0
TELADOC HEALTH INC	COM	87918A105	6,306	37,924	SH		SOLE		37,924	0	0
TELADOC HEALTH INC	NOTE 1.250% 6/0	87918AAF2	1,138	1,000	PRN		SOLE		1,000	0	0
TELEDYNE TECHNOLOGIES INC	COM	879360105	1,618	3,862	SH		SOLE		3,862	0	0
TELEFLEX INCORPORATED	COM	879369106	1,043	2,596	SH		SOLE		2,596	0	0
TELEFONICA BRASIL SA	NEW ADR	87936R205	111	13,078	SH		SOLE		13,078	0	0
TELEFONICA S A	SPONSORED ADR	879382208	3	604	SH		OTR	1	0	0	604
TELUS CORPORATION	COM	87971M103	488	21,734	SH		SOLE		21,734	0	0
TERADYNE INC	COM	880770102	1,123	8,386	SH		SOLE		8,386	0	0
TERNIUM SA	SPONSORED ADS	880890108	55,921	1,454,000	SH		SOLE		1,454,000	0	0
TERNIUM SA	SPONSORED ADS	880890108	522	500	PRN		SOLE		500	0	0
TESLA INC	COM	88160R101	1	2	SH		OTR	1	0	0	2
TESLA INC	COM	88160R101	95,694	140,754	SH		SOLE		140,754	0	0
TETRA TECH INC NEW	COM	88162G103	25,709	210,661	SH		SOLE		210,661	0	0
TETRA TECH INC NEW	COM	88162G103	3	27	SH		OTR	1	0	0	27
TEXAS INSTRS INC	COM	882508104	48,442	251,910	SH		SOLE		251,910	0	0
TEXAS INSTRS INC	COM	882508104	2	9	SH		OTR	1	0	0	9
TG THERAPEUTICS INC	COM	88322Q108	13,730	353,969	SH		SOLE		353,969	0	0
TG THERAPEUTICS INC	COM	88322Q108	1	14	SH		OTR	1	0	0	14
THE TRADE DESK INC	COM CL A	88339J105	221	2,860	SH		SOLE		2,860	0	0
THERAVANCE BIOPHARMA INC	COM	G8807B106	6,907	475,696	SH		SOLE		475,696	0	0
THERMO FISHER SCIENTIFIC INC	COM	883556102	9	17	SH		OTR	1	0	0	17
THERMO FISHER SCIENTIFIC INC	COM	883556102	178,131	353,106	SH		SOLE		353,106	0	0
THOMSON REUTERS CORP.	COM NEW	884903709	7,379	74,205	SH		SOLE		74,205	0	0
TILLYS INC	CL A	886885102	1,918	120,000	SH		SOLE		120,000	0	0
TJX COS INC NEW	COM	872540109	25,018	371,074	SH		SOLE		371,074	0	0
T-MOBILE US INC	COM	872590104	4,801	33,151	SH		SOLE		33,151	0	0
TOPBUILD CORP	COM	89055F103	5	27	SH		OTR	1	0	0	27
TOPBUILD CORP	COM	89055F103	50,181	253,722	SH		SOLE		253,722	0	0
TORONTO DOMINION BK ONT	COM NEW	891160509	9,129	130,125	SH		SOLE		130,125	0	0
TOTALENERGIES SE	SPONSORED ADS	89151E109	1	15	SH		OTR	1	0	0	15
TOYOTA MOTOR CORP	SP ADR REP2COM	892331307	6	37	SH		OTR	1	0	0	37
TPI COMPOSITES INC	COM	87266J104	1,636	33,783	SH		SOLE		33,783	0	0
TRACTOR SUPPLY CO	COM	892356106	6,133	32,960	SH		SOLE		32,960	0	0
TRANE TECHNOLOGIES PLC	SHS	G8994E103	4	22	SH		OTR	1	0	0	22
TRANSUNION	COM	89400J107	1,618	14,739	SH		SOLE		14,739	0	0
TRAVELERS COMPANIES INC	COM	89417E109	18,305	122,272	SH		SOLE		122,272	0	0
TRAVELERS COMPANIES INC	COM	89417E109	1	8	SH		OTR	1	0	0	8
TREACE MED CONCEPTS INC	COM	89455T109	625	20,000	SH		SOLE		20,000	0	0
TREX CO INC	COM	89531P105	2	20	SH		OTR	1	0	0	20
TREX CO INC	COM	89531P105	17,364	169,887	SH		SOLE		169,887	0	0
TRILLIUM THERAPEUTICS INC	COM NEW	89620X506	1	52	SH		OTR	1	0	0	52
TRILLIUM THERAPEUTICS INC	COM NEW	89620X506	7,663	790,046	SH		SOLE		790,046	0	0
TRIMBLE INC	COM	896239100	7	81	SH		OTR	1	0	0	81
TRIMBLE INC	COM	896239100	112,877	1,379,405	SH		SOLE		1,379,405	0	0
TRIP COM GROUP LTD	ADS	89677Q107	2,231	62,910	SH		SOLE		62,910	0	0
TRUIST FINL CORP	COM	89832Q109	5,176	93,260	SH		SOLE		93,260	0	0
TURNING POINT THERAPEUTICS I	COM	90041T108	2	21	SH		OTR	1	0	0	21
TURNING POINT THERAPEUTICS I	COM	90041T108	40,618	520,604	SH		SOLE		520,604	0	0
TWILIO INC	CL A	90138F102	5,764	14,623	SH		SOLE		14,623	0	0
TWIST BIOSCIENCE CORP	COM	90184D100	9,706	72,841	SH		SOLE		72,841	0	0
TWITTER INC	COM	90184L102	3,157	45,873	SH		SOLE		45,873	0	0
TWITTER INC	NOTE 1.000% 9/1	90184LAD4	3,273	203,000	PRN		SOLE		203,000	0	0
TYLER TECHNOLOGIES INC	COM	902252105	903	1,996	SH		SOLE		1,996	0	0
U S CONCRETE INC	COM	90333L201	6,163	83,516	SH		SOLE		83,516	0	0
UBER TECHNOLOGIES INC	COM	90353T100	1,438	28,687	SH		SOLE		28,687	0	0
UDR INC	COM	902653104	318	6,499	SH		SOLE		6,499	0	0
UGI CORP NEW	COM	902681105	1,741	37,599	SH		SOLE		37,599	0	0
ULTA BEAUTY INC	COM	90384S303	1,649	4,769	SH		SOLE		4,769	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	4,718	49,480	SH		SOLE		49,480	0	0
UMPQUA HLDGS CORP	COM	904214103	7,148	387,416	SH		SOLE		387,416	0	0
UNDER ARMOUR INC	CL A	904311107	3,343	3,500	PRN		SOLE		3,500	0	0
UNDER ARMOUR INC	CL A	904311107	401	18,978	SH		SOLE		18,978	0	0
UNILEVER PLC	SPON ADR NEW	904767704	3,662	62,604	SH		SOLE		62,604	0	0
UNILEVER PLC	SPON ADR NEW	904767704	5	80	SH		OTR	1	0	0	80
UNION PAC CORP	COM	907818108	15,116	68,730	SH		SOLE		68,730	0	0
UNITED PARCEL SERVICE INC	CL B	911312106	39,864	191,681	SH		SOLE		191,681	0	0
UNITED RENTALS INC	COM	911363109	5,180	16,237	SH		SOLE		16,237	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	6	14	SH		OTR	1	0	0	14
UNITEDHEALTH GROUP INC	COM	91324P102	137,463	343,279	SH		SOLE		343,279	0	0
UNIVERSAL DISPLAY CORP	COM	91347P105	2	9	SH		OTR	1	0	0	9
UNIVERSAL DISPLAY CORP	COM	91347P105	41,451	186,439	SH		SOLE		186,439	0	0
US BANCORP DEL	COM NEW	902973304	4,947	86,836	SH		SOLE		86,836	0	0
V F CORP	COM	918204108	1	18	SH		OTR	1	0	0	18
V F CORP	COM	918204108	27,463	334,753	SH		SOLE		334,753	0	0
VAIL RESORTS INC	COM	91879Q109	15,622	49,357	SH		SOLE		49,357	0	0
VALE S A	SPONSORED ADS	91912E105	291	12,775	SH		SOLE		12,775	0	0
VALERO ENERGY CORP	COM	91913Y100	2,383	30,514	SH		SOLE		30,514	0	0
VALMONT INDS INC	COM	920253101	3,110	13,174	SH		SOLE		13,174	0	0
VANECK VECTORS ETF TR	RARE EARTH STRAT	92189H805	988	11,630	SH		SOLE		11,630	0	0
VANGUARD INDEX FDS	LARGE CAP ETF	922908637	237	1,180	SH		SOLE		1,180	0	0
VARONIS SYS INC	COM	922280102	37,824	656,431	SH		SOLE		656,431	0	0
VEEVA SYS INC	CL A COM	922475108	6,539	21,028	SH		SOLE		21,028	0	0
VENTAS INC	COM	92276F100	1,630	28,538	SH		SOLE		28,538	0	0
VEREIT INC	COM	92339V308	929	20,218	SH		SOLE		20,218	0	0
VERISIGN INC	COM	92343E102	1,605	7,051	SH		SOLE		7,051	0	0
VERISIGN INC	COM	92343E102	2	9	SH		OTR	1	0	0	9
VERISK ANALYTICS INC	COM	92345Y106	1,913	10,947	SH		SOLE		10,947	0	0
VERIZON COMMUNICATIONS INC	COM	92343V104	5	83	SH		OTR	1	0	0	83
VERIZON COMMUNICATIONS INC	COM	92343V104	56,170	1,002,494	SH		SOLE		1,002,494	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	162,887	807,853	SH		SOLE		807,853	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	3	14	SH		OTR	1	0	0	14
VIACOMCBS INC	CL B	92556H206	1,225	27,100	SH		SOLE		27,100	0	0
VIATRIS INC	COM	92556V106	3,942	275,840	SH		SOLE		275,840	0	0
VIEWRAY INC	COM	92672L107	8,183	1,239,817	SH		SOLE		1,239,817	0	0
VIEWRAY INC	COM	92672L107	0	75	SH		OTR	1	0	0	75
VIPSHOP HOLDINGS LIMITED	SPONSORED ADS A	92763W103	30,394	1,513,624	SH		SOLE		1,513,624	0	0
VISA INC	COM CL A	92826C839	111,333	476,150	SH		SOLE		476,150	0	0
VISA INC	COM CL A	92826C839	4	18	SH		OTR	1	0	0	18
VMWARE INC	CL A COM	928563402	24,371	152,345	SH		SOLE		152,345	0	0
VMWARE INC	CL A COM	928563402	2	12	SH		OTR	1	0	0	12
VODAFONE GROUP PLC NEW	SPONSORED ADR	92857W308	1	55	SH		OTR	1	0	0	55
VONAGE HLDGS CORP	COM	92886T201	1,253	75,700	SH		SOLE		75,700	0	0
VORNADO RLTY TR	SH BEN INT	929042109	954	20,447	SH		SOLE		20,447	0	0
VOYA FINANCIAL INC	COM	929089100	300	4,872	SH		SOLE		4,872	0	0
VULCAN MATLS CO	COM	929160109	1,604	9,215	SH		SOLE		9,215	0	0
WABTEC	COM	929740108	2,134	25,931	SH		SOLE		25,931	0	0
WALGREENS BOOTS ALLIANCE INC	COM	931427108	3,309	62,901	SH		SOLE		62,901	0	0
WALGREENS BOOTS ALLIANCE INC	COM	931427108	1	27	SH		OTR	1	0	0	27
WALMART INC	COM	931142103	2,436	17,273	SH		SOLE		17,273	0	0
WASTE CONNECTIONS INC	COM	94106B101	3	21	SH		OTR	1	0	0	21
WASTE CONNECTIONS INC	COM	94106B101	29,827	249,747	SH		SOLE		249,747	0	0
WASTE MGMT INC DEL	COM	94106L109	10	74	SH		OTR	1	0	0	74
WASTE MGMT INC DEL	COM	94106L109	93,343	666,212	SH		SOLE		666,212	0	0
WATERS CORP	COM	941848103	8,679	25,112	SH		SOLE		25,112	0	0
WAYFAIR INC	CL A	94419L101	1,330	4,213	SH		SOLE		4,213	0	0
WEIBO CORP	NOTE 1.250%11/1	948596AC5	3,903	4,000	PRN		SOLE		4,000	0	0
WELLS FARGO CO NEW	COM	949746101	10,609	234,246	SH		SOLE		234,246	0	0
WELLTOWER INC	COM	95040Q104	5,340	64,256	SH		SOLE		64,256	0	0
WEST PHARMACEUTICAL SVSC INC	COM	955306105	24,691	68,759	SH		SOLE		68,759	0	0
WESTERN DIGITAL CORP.	COM	958102105	1,244	17,481	SH		SOLE		17,481	0	0
WESTERN DIGITAL CORP.	NOTE 1.500% 2/0	958102AP0	12,907	12,000	PRN		SOLE		12,000	0	0
WESTERN UN CO	COM	959802109	728	31,709	SH		SOLE		31,709	0	0
WESTPAC BANKING CORP	SPONSORED ADR	961214301	2	97	SH		OTR	1	0	0	97
WESTROCK CO	COM	96145D105	1,040	19,549	SH		SOLE		19,549	0	0
WEYERHAEUSER CO MTN BE	COM NEW	962166104	16,271	472,721	SH		SOLE		472,721	0	0
WHEATON PRECIOUS METALS CORP	COM	962879102	749	16,990	SH		SOLE		16,990	0	0
WHIRLPOOL CORP	COM	963320106	916	4,203	SH		SOLE		4,203	0	0
WILLIAMS COS INC	COM	969457100	2,556	96,283	SH		SOLE		96,283	0	0
WORKDAY INC	CL A	98138H101	3,146	13,177	SH		SOLE		13,177	0	0
WORKIVA INC	COM CL A	98139A105	1,113	10,000	SH		SOLE		10,000	0	0
WP CAREY INC	COM	92936U109	1,216	16,296	SH		SOLE		16,296	0	0
WYNN RESORTS LTD	COM	983134107	933	7,629	SH		SOLE		7,629	0	0
XENCOR INC	COM	98401F105	17,401	504,522	SH		SOLE		504,522	0	0
XENCOR INC	COM	98401F105	1	22	SH		OTR	1	0	0	22
XENON PHARMACEUTICALS INC	COM	98420N105	13,327	715,722	SH		SOLE		715,722	0	0
XILINX INC	COM	983919101	17,989	124,372	SH		SOLE		124,372	0	0
XP INC	CL A	G98239109	2,178	50,000	SH		SOLE		50,000	0	0
XPENG INC	ADS	98422D105	416	9,375	SH		SOLE		9,375	0	0
XPO LOGISTICS INC	COM	983793100	845	6,044	SH		SOLE		6,044	0	0
XYLEM INC	COM	98419M100	3	26	SH		OTR	1	0	0	26
XYLEM INC	COM	98419M100	35,797	298,405	SH		SOLE		298,405	0	0
YAMANA GOLD INC	COM	98462Y100	145	34,308	SH		SOLE		34,308	0	0
YETI HLDGS INC	COM	98585X104	3,431	37,369	SH		SOLE		37,369	0	0
Y-MABS THERAPEUTICS INC	COM	984241109	3,242	3,000	PRN		SOLE		3,000	0	0
Y-MABS THERAPEUTICS INC	COM	984241109	6,022	178,169	SH		SOLE		178,169	0	0
Y-MABS THERAPEUTICS INC	COM	984241109	0	12	SH		OTR	1	0	0	12
YUM BRANDS INC	COM	988498101	2,156	18,741	SH		SOLE		18,741	0	0
YUM CHINA HLDGS INC	COM	98850P109	4,346	65,600	SH		SOLE		65,600	0	0
ZAI LAB LTD	ADR	98887Q104	11,618	65,643	SH		SOLE		65,643	0	0
ZAI LAB LTD	ADR	98887Q104	1,606	1,500	PRN		SOLE		1,500	0	0
ZAI LAB LTD	ADR	98887Q104	1	5	SH		OTR	1	0	0	5
ZEBRA TECHNOLOGIES CORPORATI	CL A	989207105	6,911	13,053	SH		SOLE		13,053	0	0
ZENDESK INC	COM	98936J101	775	5,369	SH		SOLE		5,369	0	0
ZENTALIS PHARMACEUTICALS INC	COM	98943L107	1	14	SH		OTR	1	0	0	14
ZENTALIS PHARMACEUTICALS INC	COM	98943L107	11,093	208,512	SH		SOLE		208,512	0	0
ZILLOW GROUP INC	CL C CAP STK	98954M200	1,323	10,826	SH		SOLE		10,826	0	0
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	1	8	SH		OTR	1	0	0	8
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	25,790	160,363	SH		SOLE		160,363	0	0
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	779	500	PRN		SOLE		500	0	0
ZIONS BANCORPORATION N A	COM	989701107	378	7,147	SH		SOLE		7,147	0	0
ZOETIS INC	CL A	98978V103	10,029	53,816	SH		SOLE		53,816	0	0
ZOGENIX INC	COM NEW	98978L204	9,275	536,758	SH		SOLE		536,758	0	0
ZOOM VIDEO COMMUNICATIONS IN	CL A	98980L101	4,153	10,731	SH		SOLE		10,731	0	0
ZSCALER INC	COM	98980G102	13,593	62,914	SH		SOLE		62,914	0	0
ZTO EXPRESS CAYMAN INC	SPONSORED ADS A	98980A105	1,518	50,000	SH		SOLE		50,000	0	0
ZYMEWORKS INC	COM	98985W102	1	17	SH		OTR	1	0	0	17
ZYMEWORKS INC	COM	98985W102	16,412	473,107	SH		SOLE		473,107	0	0
ZYNGA INC	CL A	98986T108	273	25,700	SH		SOLE		25,700	0	0