Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the reference to our firm under the caption “Experts” in this Registration Statement (FormS-3) and related Prospectus of Clearside Biomedical, Inc. filed on May 8, 2020 for the registration of common stock, preferred stock, debt securities, and warrants and to the incorporation by reference therein of our report dated March 13, 2020, with respect to the financial statements of Clearside Biomedical, Inc. included in its Annual Report (Form10-K) for the year ended December 31, 2019, filed with the Securities and Exchange Commission.
/s/ Ernst & Young LLP
Atlanta, Georgia
May 8, 2020
