Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the reference to our firm under the caption "Experts" in this Registration Statement (Form S-3) and related Prospectus of Clearside Biomedical, Inc. filed on January 10, 2020 for the registration of common stock and to the incorporation by reference therein of our report dated March 14, 2019, with respect to the financial statements of Clearside Biomedical, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2018, filed with the Securities and Exchange Commission.
/s/ Ernst & Young LLP
Atlanta, Georgia
January 10, 2020