The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
| UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACTINIUM PHARMACEUTICALS INC | COM | 00507W107 | 13,006 | 37,000,000 | SH | SOLE | 37,000,000 | 0 | 0 | ||
| ADMA BIOLOGICS INC | COM | 000899104 | 7,789 | 2,658,290 | SH | SOLE | 2,658,290 | 0 | 0 | ||
| AKEBIA THERAPEUTICS INC | COM | 00972D105 | 95,485 | 7,031,283 | SH | SOLE | 7,031,283 | 0 | 0 | ||
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 | 327 | 10,000 | SH | SOLE | 10,000 | 0 | 0 | ||
| APREA THERAPEUTICS INC | COM | 03836J102 | 48,560 | 1,252,185 | SH | SOLE | 1,252,185 | 0 | 0 | ||
| APTOSE BIOSCIENCES INC | COM NEW | 03835T200 | 43,980 | 6,969,904 | SH | SOLE | 6,969,904 | 0 | 0 | ||
| ARAVIVE INC | COM | 03890D108 | 11,226 | 964,456 | SH | SOLE | 964,456 | 0 | 0 | ||
| ASSEMBLY BIOSCIENCES INC | COM | 045396108 | 74,053 | 3,175,535 | SH | SOLE | 3,175,535 | 0 | 0 | ||
| ATARA BIOTHERAPEUTICS INC | COM | 046513107 | 76,321 | 5,238,218 | SH | SOLE | 5,238,218 | 0 | 0 | ||
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 75,097 | 4,621,325 | SH | SOLE | 4,621,325 | 0 | 0 | ||
| AXOVANT GENE THERAPIES | COM | G0750W203 | 10,302 | 3,653,303 | SH | SOLE | 3,653,303 | 0 | 0 | ||
| BELLUS HEALTH INC NEW | COM NEW | 07987C204 | 19,783 | 1,922,503 | SH | SOLE | 1,922,503 | 0 | 0 | ||
| CAREDX INC | COM | 14167L103 | 79,101 | 2,232,612 | SH | SOLE | 2,232,612 | 0 | 0 | ||
| CHEMOCENTRYX INC | COM | 16383L106 | 98,188 | 1,706,426 | SH | SOLE | 1,706,426 | 0 | 0 | ||
| COMPUGEN LTD | ORD | M25722105 | 61,243 | 4,077,421 | SH | SOLE | 4,077,421 | 0 | 0 | ||
| CYTOKINETICS INC | COM NEW | 23282W605 | 78,894 | 3,347,232 | SH | SOLE | 3,347,232 | 0 | 0 | ||
| GENMARK DIAGNOSTICS INC | COM | 372309104 | 101,418 | 6,894,481 | SH | SOLE | 6,894,481 | 0 | 0 | ||
| HARPOON THERAPEUTICS INC | COM | 41358P106 | 14,013 | 844,162 | SH | SOLE | 844,162 | 0 | 0 | ||
| IVERIC BIO INC | COM | 46583P102 | 23,718 | 4,650,565 | SH | SOLE | 4,650,565 | 0 | 0 | ||
| KADMON HLDGS INC | COM | 48283N106 | 80,438 | 15,710,548 | SH | SOLE | 15,710,548 | 0 | 0 | ||
| KARYOPHARM THERAPEUTICS INC | COM | 48576U106 | 122,955 | 6,491,812 | SH | SOLE | 6,491,812 | 0 | 0 | ||
| KINIKSA PHARMACEUTICALS LTD | COM CL A | G5269C101 | 72,449 | 2,843,384 | SH | SOLE | 2,843,384 | 0 | 0 | ||
| LIMINAL BIOSCIENCES INC | COM | 53272L103 | 35,426 | 3,287,311 | SH | SOLE | 3,287,311 | 0 | 0 | ||
| MACROGENICS INC | COM | 556099109 | 112,840 | 4,041,535 | SH | SOLE | 4,041,535 | 0 | 0 | ||
| MERSANA THERAPEUTICS INC | COM | 59045L106 | 137,974 | 5,896,326 | SH | SOLE | 5,896,326 | 0 | 0 | ||
| OMEROS CORP | COM | 682143102 | 61,381 | 4,169,872 | SH | SOLE | 4,169,872 | 0 | 0 | ||
| OVID THERAPEUTICS INC | COM | 690469101 | 18,947 | 2,570,878 | SH | SOLE | 2,570,878 | 0 | 0 | ||
| SAREPTA THERAPEUTICS INC | COM | 803607100 | 68,259 | 425,716 | SH | SOLE | 425,716 | 0 | 0 | ||
| SILK RD MED INC | COM | 82710M100 | 209 | 5,000 | SH | SOLE | 5,000 | 0 | 0 | ||
| SOLENO THERAPEUTICS INC | COM NEW | 834203200 | 6,749 | 3,040,000 | SH | SOLE | 3,040,000 | 0 | 0 | ||
| STEREOTAXIS INC | COM NEW | 85916J409 | 16,317 | 3,658,537 | SH | SOLE | 3,658,537 | 0 | 0 | ||
| UNIQURE NV | SHS | N90064101 | 2,253 | 50,000 | SH | SOLE | 50,000 | 0 | 0 | ||