Ignyta, Inc.
11111 Flintkote Avenue
San Diego, CA 92121
March 12, 2015
VIA EDGAR
Jeffrey P. Riedler
Assistant Director
Division of Corporation Finance
Securities and Exchange Commission
100 F Street, N.E.
Washington, D.C. 20549
| Re: | Ignyta, Inc. |
| Registration Statement on Form S-3 |
| Filed March 2, 2015 |
| File No. 333-202403 |
Dear Mr. Riedler:
Pursuant to Rule 461 of Regulation C of the General Rules and Regulations under the Securities Act of 1933, as amended, the undersigned, on behalf Ignyta, Inc. (the “Company”), respectfully requests that the effective date of the Registration Statement on Form S-3 referred to above be accelerated so that it will become effective at 4:00 P.M. Eastern Time on Friday, March 13, 2015, or as soon as practicable thereafter.
The undersigned, on behalf of the Company, acknowledges the following:
| • | should the Commission or the staff, acting pursuant to delegated authority, declare the filing effective, it does not foreclose the Commission from taking any action with respect to the filing; |
| • | the action of the Commission or the staff, acting pursuant to delegated authority, in declaring the filing effective, does not relieve the Company from its full responsibility for the adequacy and accuracy of the disclosure in the filing; and |
| • | the Company may not assert staff comments and the declaration of effectiveness as a defense in any proceeding initiated by the Commission or any person under the federal securities laws of the United States. |
If you have any questions or require additional information, please contact Cheston J. Larson, Esq. of Latham & Watkins LLP at (858) 523-5435. Thank you for your assistance and cooperation in this matter.
| Very truly yours, | ||
| IGNYTA, INC. | ||
| By: | /s/ Jonathan E. Lim, M.D. | |
| Jonathan E. Lim, M.D. | ||
| President and Chief Executive Officer | ||
| cc: | Cheston J. Larson, Esq., Latham & Watkins LLP |
