Prothena Corporation plc
77 Sir John Rogerson’s Quay, Block C
Grand Canal Docklands
Dublin 2, D02 T804, Ireland
June 7, 2019
VIA EDGAR TRANSMISSION
U.S. Securities and Exchange Commission
Division of Corporation Finance
Office of Healthcare & Insurance
100 F Street, N.E.
Washington, DC 20549
| Attention: | Frank Wyman | |||
| Tabatha McCullom | ||||
| Re: | Prothena Corporation plc | |||
| Form 10-K for the Year Ended December 31, 2017 | ||||
| Filed February 26, 2018 | ||||
| Form 10-Q for the Quarterly Period Ended September 30, 2018 | ||||
| Filed November 6, 2018 | ||||
| File No. 001-35676 | ||||
Ladies and Gentlemen:
This letter is to confirm the receipt of your letter dated May 29, 2019 (the “SEC Comment Letter”) regarding the Annual Report on Form 10-K for the year ended December 31, 2017 and the Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2018 of Prothena Corporation plc (the “Company”). The Company plans to provide you with a response to the SEC Comment Letter on or before June 19, 2019.
If you have any questions regarding the foregoing, please call John C. Williams of Latham & Watkins LLP at (650) 470-4887 or the undersigned at (650) 615-2113.
| Very truly yours, |
| /s/ A. W. Homan |
| A. W. Homan |
| Chief Legal Officer and Company Secretary |
| cc: | Tran B. Nguyen |
Karin Walker
Kathleen Wells
