August 14, 2013
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
| Re: | Sophiris Bio Inc. (the “Company”) – Request for Acceleration |
| Registration Statement on Form S-1 (File No. 333-186724) |
Ladies and Gentlemen:
In accordance with Rule 461 under the Securities Act of 1933, as amended (the “Act”), and as Representatives of the several underwriters of the Company’s proposed public offering of common shares, we hereby join the Company’s request for acceleration of the above-referenced Registration Statement, as amended, requesting effectiveness for 5:15 p.m. Eastern Time on August 15, 2013, or as soon thereafter as is practicable.
Pursuant to Rule 460 of the Act, we wish to advise you that we have distributed approximately 1,170 copies of the Company’s Preliminary Prospectus dated August 7, 2013 through the date hereof to underwriters, dealers, institutions and others.
We, the undersigned, as Representatives of the several underwriters, have and will, and we have been informed by the participating underwriters that they have complied and will continue to comply, with the provisions of Rule 15c2-8 of the Securities Exchange Act of 1934, as amended.
[Signature Page Follows]
| Very truly yours, | ||||
| Citigroup Global Markets Inc. | ||||
| Leerink Swann LLC | ||||
| As Representatives of the several Underwriters | ||||
| By: Citigroup Global Markets Inc. | ||||
| By: | /s/ Chris Collins | |||
| Name: | Chris Collins | |||
| Title: | Vice President | |||
| By: Leerink Swann LLC | ||||
| By: | /s/ Bryan Giraudo | |||
| Name: | Bryan Giraudo | |||
| Title: | Managing Director | |||
