Sarissa Capital Management Form 3 Iterum Therapeutics / ALEXANDER J DENNER ownership change

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

DENNER ALEXANDER J

(Last) (First) (Middle)

C/O SARISSA CAPITAL MANAGEMENT LP

660 STEAMBOAT ROAD, 3RD FLOOR

(Street)

GREENWICH CT 06830

(City) (State) (Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
11/22/2020

3. Issuer Name and Ticker or Trading Symbol
Iterum Therapeutics plc [ ITRM ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

Director	X	10% Owner
Officer (give title below)		Other (specify below)

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
6.500% Exchangeable Senior Subordinated Note due 2025	01/21/2021	01/31/2025	Ordinary Shares	19,292,768(1)(2)(3)(4)	0.7775	I	See footnotes(1)(2)(3)(4)

1. Name and Address of Reporting Person^*

DENNER ALEXANDER J

(Last) (First) (Middle)

C/O SARISSA CAPITAL MANAGEMENT LP

660 STEAMBOAT ROAD, 3RD FLOOR

(Street)

GREENWICH CT 06830

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Sarissa Capital Management LP

(Last) (First) (Middle)

660 STEAMBOAT ROAD

3RD FLOOR

(Street)

GREENWICH CT 06830

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Sarissa Capital Offshore Master Fund LP

(Last) (First) (Middle)

C/O SARISSA CAPITAL MANAGEMENT

660 STEAMBOAT ROAD 3RD FLOOR

(Street)

GREENWICH CT 06830

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Sarissa Capital Catapult Fund LLC

(Last) (First) (Middle)

C/O SARISSA CAPITAL MANAGEMENT LP

660 STEAMBOAT ROAD, 3RD FLOOR

(Street)

GREENWICH CT 06830

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Sarissa Capital Hawkeye Fund LP

(Last) (First) (Middle)

C/O SARISSA CAPITAL MANAGEMENT LP

660 STEAMBOAT ROAD, 3RD FLOOR

(Street)

GREENWICH CT 06830

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Sarissa Capital Master Fund II LP

(Last) (First) (Middle)

C/O SARISSA CAPITAL MANAGEMENT LP

660 STEAMBOAT ROAD, 3RD FLOOR

(Street)

GREENWICH CT 06830

(City) (State) (Zip)

Explanation of Responses:

1. See Exhibit 99.1

2. See Exhibit 99.1

3. See Exhibit 99.1

4. See Exhibit 99.1

Remarks:

Exhibit List: ------------- Exhibit 99.1

	SARISSA CAPITAL MANAGEMENT LP; By: /s/ Mark DePaolo, Senior Partner, General Counsel	11/23/2020
	SARISSA CAPITAL OFFSHORE MASTER FUND LP; By: /s/ Mark DiPaolo, Authorized Person	11/23/2020
	SARISSA CAPITAL CATAPULT FUND LLC; /s/ Mark DiPaolo, Authorized Person	11/23/2020
	SARISSA CAPITAL HAWKEYE FUND LP; By: /s/ Mark DiPaolo, Authorized Person	11/23/2020
	SARISSA CAPITAL MASTER FUND II LP; By: /s/ Mark DiPaolo, Authorized Person	11/23/2020
	/s/ Alexander J. Denner	11/23/2020
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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