By instructing your securities intermediary to tender ADSs you will be deemed to have covenanted, represented and warranted to Takeda that:
(a) you have full power and authority to tender, sell, assign and transfer the ADSs tendered on your behalf and that when and to the extent Takeda accepts the Ordinary Shares represented by such ADSs for purchase, Takeda will acquire good, marketable and unencumbered title to the tendered Ordinary Shares represented by such ADSs, free and clear of all security interests, liens, charges, encumbrances, conditional sales agreements or other obligations relating to their sale or transfer, and not subject to any adverse claim;
(b) on request, you will execute and deliver any additional documents deemed by the U.S. ADS Tender Agent or Takeda to be necessary or desirable to complete the assignment, transfer and purchase of the Ordinary Shares represented by such ADSs tendered hereby; and
(c) the undersigned agrees to all of the terms of the U.S. Offer.
By instructing your securities intermediary to tender ADSs you will be deemed to understand that (a) tendering of ADSs under any one of the procedures described in this ADS Letter of Transmittal will constitute a binding agreement between the holder and/or owner of the ADSs so tendered and Takeda upon the terms and subject to the conditions of the U.S. Offer and (b) all Ordinary Shares represented by ADSs properly tendered prior to the Initial Expiration Date or prior to the date and time of the expiration of any Subsequent Offering Period or the Squeeze-Out Period, as applicable, and not properly withdrawn will be purchased at the Offer Price, net to the seller in cash, without interest, on the terms and subject to the conditions of the U.S Offer.
By instructing your securities intermediary to tender ADSs you will be deemed to recognize that under certain circumstances set forth in the U.S. Offer to Purchase, Takeda may terminate or amend the U.S. Offer or may postpone the acceptance for payment of, or the payment for, the Ordinary Shares represented by ADSs that have been tendered or may accept for payment fewer than all of the Ordinary Shares represented by ADSs tendered hereby. In such event, you will be deemed to understand that any ADSs delivered on your behalf into the U.S. Offer but with respect to which the underlying Ordinary Shares are not purchased, will be returned to your securities intermediary.
By instructing your securities intermediary to tender ADSs you will be deemed to understand and agree that (i) acceptance of Ordinary Shares represented by ADSs by Takeda for payment will constitute a binding agreement between you and Takeda on the terms and subject to the conditions of the U.S. Offer and (ii) no interest will be paid on the Offer Price for the Ordinary Shares represented by tendered ADSs.
All authority deemed to be conferred or agreed to be conferred in this ADS Letter of Transmittal shall survive the death or incapacity of the holder and/or owner of ADSs tendered, and any obligation or duties of such holder and/or owner under this ADS Letter of Transmittal shall be binding upon the heirs, personal representatives, executors, administrators, successors, assigns, trustees in bankruptcy and legal representatives of the undersigned. Except as stated in the U.S. Offer to Purchase, any tender is irrevocable.