Document and Entity Information
Document and Entity Information - shares | 6 Months Ended | |
Jun. 30, 2015 | Aug. 13, 2015 | |
Document And Entity Information [Abstract] | ||
Document Type | 10-Q | |
Amendment Flag | false | |
Document Period End Date | Jun. 30, 2015 | |
Document Fiscal Year Focus | 2,015 | |
Document Fiscal Period Focus | Q2 | |
Trading Symbol | PIRS | |
Entity Registrant Name | PIERIS PHARMACEUTICALS, INC. | |
Entity Central Index Key | 1,583,648 | |
Current Fiscal Year End Date | --12-31 | |
Entity Filer Category | Smaller Reporting Company | |
Entity Common Stock, Shares Outstanding | 39,732,258 |
Condensed Consolidated Balance
Condensed Consolidated Balance Sheets - USD ($) | Jun. 30, 2015 | Dec. 31, 2014 |
Current assets: | ||
Cash and cash equivalents | $ 10,027,305 | $ 18,474,211 |
Other current assets | 1,866,180 | 1,207,072 |
Prepaid expenses | 732,221 | 109,332 |
Income tax receivable | 16,015 | 14,810 |
Total current assets | 12,641,721 | 19,805,425 |
Property and equipment, net | 1,811,356 | 2,052,221 |
Deferred tax asset | 24,446 | 26,522 |
Total assets | 14,477,523 | 21,884,168 |
Current liabilities: | ||
Trade accounts payable | 2,058,458 | 1,260,015 |
Accrued expenses | 635,561 | 743,865 |
Other current liabilities | 304,012 | 242,755 |
Bank loan | 1,270,605 | |
Deferred tax liabilities | 24,446 | 26,522 |
Total current liabilities | 3,022,477 | 3,543,762 |
Other long-term liabilities | 307,850 | 333,988 |
Total liabilities | 3,330,327 | 3,877,750 |
Stockholders' equity | ||
Common stock, $0.001 par value per share, 300,000,000 shares authorized and 29,429,522 and 29,279,522 issued and outstanding at June 30, 2015 and December 31, 2014 | 29,430 | 29,280 |
Additional paid-in capital | 85,503,241 | 84,627,283 |
Accumulated other comprehensive loss | (1,343,694) | (843,097) |
Accumulated deficit | (73,041,781) | (65,807,048) |
Total stockholders' equity | 11,147,196 | 18,006,418 |
Total liabilities and stockholders' equity | $ 14,477,523 | $ 21,884,168 |
Condensed Consolidated Balance3
Condensed Consolidated Balance Sheets (Parenthetical) - $ / shares | Jun. 30, 2015 | Dec. 31, 2014 |
Statement of Financial Position [Abstract] | ||
Common stock, par value | $ 0.001 | $ 0.001 |
Common stock, shares authorized | 300,000,000 | 300,000,000 |
Common stock, shares issued | 29,429,522 | 29,279,522 |
Common stock, outstanding | 29,429,522 | 29,279,522 |
Condensed Consolidated Statemen
Condensed Consolidated Statements of Operations - USD ($) | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2015 | Jun. 30, 2014 | Jun. 30, 2015 | Jun. 30, 2014 | |
Income Statement [Abstract] | ||||
Revenue | $ 160,244 | $ 698,227 | $ 377,864 | $ 2,071,106 |
Operating costs and expenses | ||||
Research and development | (1,725,592) | (1,118,920) | (3,250,222) | (2,341,666) |
General and administrative | (1,969,082) | (2,349,232) | (4,363,405) | (3,170,582) |
Costs and expenses | (3,694,674) | (3,468,152) | (7,613,627) | (5,512,248) |
Loss from operations | (3,534,430) | (2,769,925) | (7,235,763) | (3,441,142) |
Other income (expense) | ||||
Interest expense | (53) | (113,793) | (4,223) | (223,083) |
Other income, net | 4,484 | 2,081 | 5,253 | 2,665 |
Loss before income taxes | (3,529,999) | (2,881,637) | (7,234,733) | (3,661,560) |
Income tax benefit | 18 | |||
Net loss | $ (3,529,999) | $ (2,881,637) | $ (7,234,733) | $ (3,661,542) |
Net loss per share Basic and diluted | $ (0.12) | $ (0.24) | $ (0.25) | $ (0.31) |
Weighted average number of common shares outstanding Basic and diluted | 29,429,522 | 11,828,974 | 29,361,566 | 11,828,974 |
Consolidated Statements of Comp
Consolidated Statements of Comprehensive Income (Loss) - USD ($) | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2015 | Jun. 30, 2014 | Jun. 30, 2015 | Jun. 30, 2014 | |
Statement of Comprehensive Income [Abstract] | ||||
Net loss | $ (3,529,999) | $ (2,881,637) | $ (7,234,733) | $ (3,661,542) |
Other comprehensive loss | ||||
Foreign currency translation adjustments | 102,135 | 6,654 | (500,597) | 3,027 |
Total other comprehensive loss, after tax | 102,135 | 6,654 | (500,597) | 3,027 |
Comprehensive loss | $ (3,427,864) | $ (2,874,983) | $ (7,735,330) | $ (3,658,515) |
Condensed Consolidated Stateme6
Condensed Consolidated Statements of Cash Flows - USD ($) | 6 Months Ended | |
Jun. 30, 2015 | Jun. 30, 2014 | |
Cash flows from operating activities: | ||
Net loss | $ (7,234,733) | $ (3,661,542) |
Adjustments to reconcile net loss to net cash provided by operating activities: | ||
Depreciation | 154,555 | 189,463 |
Non-cash interest expense | 181,951 | |
Stock-based compensation expense | 485,374 | |
Non-cash Restricted shares | 390,734 | |
Changes in operating assets and liabilities: | ||
Restricted cash | 13,091 | |
Trade accounts receivable | 68,553 | |
Prepaid expenses | (628,723) | (72,570) |
Other assets | (768,905) | (240,743) |
Trade accounts payable | 897,130 | 487,595 |
Accrued and other liabilities | 30,481 | (422,410) |
Income taxes | (2,365) | 49,668 |
Net cash used in operations | (6,676,452) | (3,406,942) |
Cash flows from investing activities: | ||
Purchase of property and equipment | (74,286) | (4,961) |
Net cash used in investing activities | (72,286) | (4,961) |
Cash flows from financing activities: | ||
Proceeds of loans | 1,361,460 | |
Repayment of debt | (1,171,170) | (136,900) |
Net cash (used in)/provided by financing activities | (1,171,170) | 1,224,560 |
Effect of exchange rate change on cash and cash equivalents | (524,998) | (17,033) |
Net decrease in cash and cash equivalents | (8,446,906) | (2,204,376) |
Cash and cash equivalents at beginning of period | 18,474,211 | 3,689,382 |
Cash and cash equivalents at end of period | 10,027,305 | 1,485,006 |
Supplemental cash flow disclosures: | ||
Cash paid for interest | 4,224 | 41,132 |
Cash received for income taxes | $ (1,206) | $ (18) |
Corporate Information
Corporate Information | 6 Months Ended |
Jun. 30, 2015 | |
Accounting Policies [Abstract] | |
Corporate Information | 1. Corporate Information Pieris Pharmaceuticals, Inc. is a holding company incorporated in May 2013 under the name Marika Inc. On December 17, 2014 Pieris AG (a German company which was founded in 2001 by Prof. Dr. Arne Skerra, Professor at the Technical University of Munich, Germany, and Claus Schalper) became a wholly owned subsidiary of Pieris Pharmaceuticals, Inc., pursuant to the Acquisition (described below). The registered office of Pieris Pharmaceuticals, Inc. and the corporate headquarters and research facility of Pieris AG are located in Freising-Weihenstephan, Germany. Pieris Australia Pty Ltd., a wholly owned subsidiary of Pieris AG, was formed on February 14, 2014 to conduct research and development in Australia. On December 17, 2014, Pieris Pharmaceuticals, Inc., Pieris AG, and the former stockholders of Pieris AG entered into an acquisition agreement, or the Acquisition Agreement. Pursuant to the Acquisition Agreement, on December 17, 2014, the stockholders of Pieris AG contributed all of their equity interests in Pieris AG to Pieris Pharmaceuticals, Inc. in exchange for shares of Pieris Pharmaceuticals, Inc. common stock, which resulted in Pieris AG becoming a wholly owned subsidiary of Pieris Pharmaceuticals, Inc. (the “Acquisition”). Upon the closing of the Acquisition, Pieris Pharmaceuticals, Inc. ceased to be a “shell company” under applicable rules of the SEC. For more information on the acquisition, please refer to Note 3 Acquisition On December 17, 2014, Pieris Pharmaceuticals, Inc. entered into a securities purchase agreement, or the Securities Purchase Agreement, with certain accredited investors (the “Investors”) providing for the issuance and sale to such Investors of an aggregate of 6,779,510 shares of our common stock in a private placement offering conducted through a series of closings occurring on December 17, 18 and 23, 2014, at a purchase price per share of $2.00 and for aggregate gross proceeds of approximately $13.56 million (the “Private Placement”). Northland Securities, Inc. and Katalyst Securities, LLC served as co-exclusive placement agents (the “Placement Agents”) for the Private Placement. At the closings of the Private Placement we issued to the Placement Agents and their designees, warrants (the “Placement Warrants”), to acquire up to 542,360 shares of our common stock at an exercise price of $2.00 per share. Each of the Placement Warrants is exercisable at any time at the option of the holder until the five-year anniversary of its date of issuance. Pieris Pharmaceuticals, Inc. and its consolidated subsidiaries (the “Company”) is a clinical-stage biopharmaceutical company dedicated to the discovery and development of the Anticalin ® The Company´s core Anticalin ® |
Basis of Presentation and Summa
Basis of Presentation and Summary of Significant Accounting Policies | 6 Months Ended |
Jun. 30, 2015 | |
Accounting Policies [Abstract] | |
Basis of Presentation and Summary of Significant Accounting Policies | 2. Basis of Presentation and Summary of Significant Accounting Policies The following is a summary of the significant accounting policies consistently applied in the preparation of the accompanying condensed consolidated financial statements. Basis of Consolidation The accompanying unaudited condensed consolidated financial statements of Pieris Pharmaceuticals Inc. and its wholly owned subsidiaries were prepared in accordance with accounting principles generally accepted in the United States (“U.S. GAAP”) for interim financial information. All significant intercompany balances and transactions have been eliminated in the consolidation. Certain information and footnotes normally included in financial statement prepared in accordance with U.S. GAAP have been omitted pursuant to the Securities and Exchange Commission rules and regulations. Accordingly, they do not include all of the information and notes required by U.S. GAAP for complete annual consolidated financial statements. In the opinion of management, the unaudited interim condensed consolidated financial statements have been prepared on the same basis as the audited condensed consolidated financial statements for the year ending December 31, 2014, and all adjustments, including normal recurring adjustments, considered necessary for a fair presentation of Pieris Pharmaceuticals, Inc.’s unaudited interim consolidated financial statements have been included. The results of operations for the three and six months ended June 30, 2015 are not necessarily indicative of the results that may be expected for the year ending December 31, 2015 or any future period. Use of estimates The preparation of the condensed consolidated financial statements in accordance with U.S. GAAP requires management to make estimates, judgments and assumptions that affect the reported amounts of assets and liabilities, the reported amounts of revenues and expenses in the financial statements and disclosures in the accompanying notes. Actual results and outcomes could differ materially from management’s estimates, judgments and assumptions. Segment Reporting Pieris Pharmaceuticals, Inc. operates as a single segment dedicated to the discovery and development of biotechnological applications and the Company’s chief operating decision maker (CODM) makes decisions based on the Company as a whole. Accordingly, Pieris Pharmaceuticals, Inc. operates and makes decisions as one reporting unit. Milestone Payments and Royalties At the inception of each agreement that includes milestone payments, Pieris Pharmaceuticals, Inc. evaluates whether each milestone is substantive and at risk to both parties on the basis of the contingent nature of the milestone. This evaluation includes an assessment of whether (a) the consideration is commensurate with either (1) the entity’s performance to achieve the milestone, or (2) the enhancement of the value of the delivered item(s) as a result of a specific outcome resulting from the entity’s performance to achieve the milestone, (b) the consideration relates solely to past performance and (c) the consideration is reasonable relative to all of the deliverables and payment terms within the arrangement. Pieris Pharmaceuticals, Inc. evaluates factors such as the scientific, regulatory, commercial and other risks that must be overcome to achieve the respective milestone, the level of effort and investment required to achieve the respective milestone and whether the milestone consideration is reasonable relative to all deliverables and payment terms in the arrangement in making this assessment. Pieris Pharmaceuticals, Inc. aggregates milestones into three categories (i) research milestones, (ii) development milestones and (iii) commercial milestones. Research milestones are typically achieved upon reaching certain success criteria as defined in each agreement related to developing an Anticalin protein against the specified target. Development milestones are typically reached when a compound reaches a defined phase of clinical research or passes such phase, or upon gaining regulatory approvals. Commercial milestones are typically achieved when an approved pharmaceutical product reaches the status for commercial sale or certain defined levels of net sales by the licensee, such as when a product first achieves global sales or annual sales of a specified amount. For revenues from research and development milestone payments, if the milestones are deemed substantive and the milestone payments are nonrefundable, such amounts are recognized entirely upon successful accomplishment of the milestones. Milestones that are not considered substantive are accounted for as license payments and recognized on a straight-line basis over the period of performance. To date, Pieris Pharmaceuticals, Inc. has determined all milestones are substantive. Revenues from commercial milestone payments are accounted for as royalties and are recorded as revenue upon achievement of the milestone, assuming all other revenue recognition criteria are met. Royalty payments are recognized in revenues based on the timing of royalty payments earned in accordance with the agreements; which typically is the period when the relevant sales occur, assuming all other revenue recognition criteria are met. Fair Value Measurement ASC Topic 820 Fair Value Measurement Level 1 inputs are quoted prices in active markets for identical assets or liabilities that the reporting entity has the ability to access at the measurement date. Level 2 utilizes quoted market prices in markets that are not active, broker or dealer quotations, or alternative pricing sources with reasonable levels of price transparency. Level 3 inputs are unobservable inputs for the asset or liability in which there is little, if any, market activity for the asset or liability at the measurement date. Cash equivalents recorded by Pieris Pharmaceuticals, Inc. consist of highly liquid money market funds and are measured at fair value on a recurring basis. These funds are classified as Level 1 in the fair value hierarchy because they are valued using quoted prices for the periods ended June 30, 2015 and December 31, 2014. The carrying amounts of $78,403 and $ 4,800,573 as of June 30, 2015 and December 31, 2014, respectively, equal the fair value of the cash equivalents. The Company’s other financial instruments include debt instruments, prepaid expenses, other current assets, accounts payable, accrued expenses and other current liabilities and are classified as Level 2 within the fair value hierarchy. The fair value of these instruments was determined using the discounted cash flow method based on contractual cash flows and the current rate at which debt with similar terms could be issued. The fair values for these debt instruments approximated carrying values as of June 30, 2015 and December 31, 2014. Income taxes Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases, and operating losses and tax credit carry forwards. Deferred tax assets and liabilities are measured using enacted statutory tax rates expected to apply to taxable income in the jurisdictions and years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. Based on the level of historical operating results and projections for the taxable income for the future, the Company has determined that it is more likely than not that the deferred tax assets will not be realized. Accordingly, the Company has recorded a valuation allowance to reduce deferred tax assets to the same amount as deferred tax liabilities and determines an effective tax rate of zero percent. Recent Accounting Pronouncements In May 2014, the FASB issued ASU No. 2014-09, “Revenue from Contracts with Customers,” (ASU 2014-09) which provides guidance for revenue recognition. The standard’s core principle is that a company will recognize revenue when it transfers promised goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for those goods or services. The new guidance is effective for annual reporting periods beginning after December 15, 2016, including interim periods within that reporting period. Early application is not permitted. On April 1, 2015 the FASB voted in favor of proposing a one year delay of the effective date and to permit companies to voluntarily adopt the new standard as of the original effective date. The Company is currently assessing the potential impact the adoption of this standard will have on their financial statements. In January 2015, the FASB issued ASU No. 2015-01, “Income Statement – Extraordinary and Unusual items” In February 2015, the FASB issued ASU No. 2015-02, “Consolidation (Topic 810): Amendments to the Consolidation Analysis” In June 2015, the FASB issued ASU No. 2015-10, “Technical Corrections and Improvements” (ASU 2015-10). The amendments in ASU 2015-10 represent changes to clarify the FASB Accounting Standards Codification (the “Codification”), correct unintended application of guidance, or make minor improvements to the Codification that are not expected to have a significant effect on current accounting practice or create a significant administrative cost to most entities. In addition, some of the amendments are intended to make the Codification easier to understand and easier to apply by eliminating inconsistencies, providing needed clarifications, and improving the presentation of guidance in the Codification. This guidance is effective for fiscal years, and interim periods within those fiscal years, beginning after December 15, 2015. The company is currently evaluating the impact of this new standard. Pieris Pharmaceuticals, Inc. has considered other recent accounting pronouncements and concluded that they are either not applicable to the business, or that the effect is not expected to be material to the unaudited condensed consolidated financial statements as a result of future adoption. |
Revenues
Revenues | 6 Months Ended |
Jun. 30, 2015 | |
Organization, Consolidation and Presentation of Financial Statements [Abstract] | |
Revenues | 3. Revenues General Pieris Pharmaceuticals, Inc. has not generated revenues from product sales. Pieris Pharmaceuticals, Inc. has generated revenues pursuant to (i) license and collaboration agreements, which include upfront payments for licenses or options to obtain licenses, payments for research and development services and milestone payments, and (ii) government grants. Collaborations and Other Agreements Allergan, Inc. In August 2009, pursuant to an agreement with Allergan, Inc. (“Allergan”), the Company granted Allergan a worldwide exclusive license to develop and commercialize certain drug candidates for the treatment and prevention of ocular diseases. Allergan is responsible for the research, development, manufacturing and commercialization of any products resulting from the license. The Company received a non-refundable upfront payment of $10 million upon execution of the contract in 2009 and is entitled to receive up to an aggregate of $13 million in milestone payments upon the achievement of certain commercial milestones or patents granted to the Company by the United States Patent and Trademark Office that cover a product licensed to Allergan. At the inception of the agreement, the Company recognized revenues from the upfront license payment because, based on the stage of development of the licensed product delivered and the development capabilities of Allergan, the Company determined that the license had standalone value. Through June 30, 2015, none of the milestones had been achieved and, as such, the Company has not recognized milestone-related revenues. Daiichi Sankyo Co., Ltd. In May 2011, the Company entered into an agreement with Daiichi Sankyo Co., Ltd. (“Daiichi Sankyo”), under which Pieris AG will use its proprietary Anticalin ® Upon execution of the agreement, Daiichi Sankyo paid the Company a non-refundable upfront payment in the amount of $10.1 million in consideration for the licenses, and for each licensed product, the Company is entitled to receive potential milestone payments of $91.1 million, plus royalties on the commercial sales of any commercial products. The total milestones are categorized as follows: research milestones - $2.6 million; development milestones - $37.4 million; commercial milestones - $50.2 million; additional diagnostic milestones of $0.9 million. At the inception of the agreement, these milestones were determined to be substantive as there was substantial uncertainty the milestones would be achieved, they would require substantial performance from the entity, and the consideration was reasonable relative to other deliverables. The agreement includes provisions for the Company to provide research services funded by Daiichi Sankyo at agreed upon full-time employee rates during the initial identification and research period. In accordance with the guidance in ASC 605-25, the Company identified the licenses and research funding as deliverables at the inception of the arrangement. The Company has determined that the licenses and research services provided by the Company represent one unit of accounting because, based on the stage of development of the licensed product, the research services provided by the Company to identify drug candidates using the Company’s proprietary Anticalin ® The Company has not recognized any milestone payments as revenue for the six months ended June 30, 2015. The Company recognized a milestone payment of $0.4 million as revenue for the six months ended June 30, 2014. The milestone payment was based on successful in vitro in vivo Sanofi-Aventis and Sanofi-Pasteur In September 2010, the Company entered into an agreement with Sanofi-Aventis and Sanofi Pasteur (“Sanofi”), under which the Company agreed to apply its proprietary Anticalin ® Upon execution of the agreement, Sanofi paid the Company an upfront payment of $4.9 million in consideration for licenses on the first two targets and options to select an additional four licenses on other targets (with each option requiring an additional upfront payment upon exercise). Additionally, for each licensed product, the Company is entitled to receive milestone payments up to $51.6 million, plus royalties on the sales of any commercial products. The total milestones are categorized as follows: research milestones - $1.9 million; development milestones - $29.6 million; commercial milestones - $20.1 million. At the inception of the agreement, these milestones were determined to be substantive because (i) there was substantial uncertainty the milestones would be achieved, (ii) they would require substantial performance from the entity, and (iii) the consideration was reasonable relative to other deliverables. The agreement included provisions for the Company to provide research services funded by Sanofi at agreed upon full-time employee equivalent rates during the initial identification and research period. In accordance with the guidance in ASC 605-25, the Company identified the licenses, options to obtain additional licenses and research funding as deliverables at the inception of the arrangement. The options were considered to be substantive at the inception of the agreement. Factors considered in determining the options were substantive were whether (i) Sanofi could obtain the overall objective of the agreement without exercising any options, (ii) Sanofi was able to obtain value from the initial licenses obtained without exercising any options, (iii) the cost to exercise the options was significant relative to the total upfront payment of $4.9 million for two licenses and four options, and (iv) exercising the option created additional financial commitments for Sanofi or imposed economic penalties on Sanofi. The Company has determined that, for each program selected by Sanofi, the license and research services provided by the Company represent one unit of accounting because, based on the stage of development of the licensed product, the research services provided by the Company to identify drug candidates using the Company’s proprietary Anticalin technology against Sanofi’s selected targets were necessary before the licenses would have any standalone value. The estimated selling prices for the licenses in the agreement are the Company’s best estimate of selling price and were determined based on market conditions and entity-specific factors such as considerations of preclinical and clinical testing results and the Company’s pricing practices and pricing objectives. The estimated selling price of research services are the Company’s best estimate of selling price and are determined based on market conditions and entity-specific factors such as internal cost considerations and the Company’s pricing practices and pricing objectives. At inception, the total arrangement consideration of $8.1 million (which comprises the $4.9 million upfront payment and the expected fees for the research services to be provided under the remainder of the arrangement) was allocated to the deliverables based on the residual method as follows: $3.5 million to the licenses, $1.4 million to the four options to acquire additional licenses and $3.2 million to the estimated research services to be provided. As the license and research services were determined to be one unit of accounting, the consideration allocated to each license is recognized over the period of substantial involvement, which was determined to be the period the Company was required to provide research services to discover drug candidates against targets identified, approximately two years. The Company reassesses the estimated term at the end of each reporting period. At the end of 2012, the Company determined that the required research term for one of the initial terms would extend to a period of 40 months, and management updated the estimated required service period to amortize the remaining deferred upfront payment over the new term. Two of the four options expired un-exercised in 2011, and as a result the Company recognized $0.7 million of revenue upon expiration. The option term for the remaining two options was extended to February 2013, and Sanofi exercised one option to obtain an additional license. For the exercised option, the allocated consideration of $0.28 million for the option and the $1.1 million payment of the exercise price of the option were deferred and amortized over the expected required service period of approximately two years. The program covered by the exercised option was terminated in December 2013, and accordingly, the Company recognized the remaining deferred revenue upon termination. The remaining option expired in February 2013 and the allocated consideration of $0.35 million was recognized into revenue at the time of expiration. The Company has not recognized any milestone payments as revenue for the three and six months ended June 30, 2015. The Company recognized a milestone payment of $0.3 million as revenue for the six months ended June 30, 2014. The Company did not recognize a milestone payment for the three months ended June 30, 2014. The milestone payment was based on successful in vivo For the three and six months ended June 30, 2015, the Company did not recognize any revenues related to the Sanofi collaboration and for the three and six months ended June 30, 2014, the Company recognized $0.2 million and $0.7 million in revenues respectively. |
Related-Party Transactions
Related-Party Transactions | 6 Months Ended |
Jun. 30, 2015 | |
Related Party Transactions [Abstract] | |
Related-Party Transactions | 4. Related-Party Transactions Research and License Agreement with Technische Universität München (“TUM”) On July 4, 2003, the Company entered into a research and licensing agreement with TUM, which was subsequently renewed and, on July 26, 2007, superseded and replaced. The agreement established a joint research effort led by Prof. Arne Skerra, Chair of Biological Chemistry of TUM, to optimize Anticalin® technologies for use in therapeutic, prophylactic and diagnostic applications and as research reagents, and to gain fundamental insights in lipocalin scaffolds. Prof. Dr. Skerra was a member of Pieris AG’s supervisory board when the parties entered into such agreement. The Company provided certain funding for TUM research efforts performed under the agreement. As a result of research efforts to date under the agreement, the Company holds a worldwide exclusive license under its license agreement with TUM to multiple patents and patent applications, including an exclusive license to an issued U.S. patent, which patent will expire in 2027 (subject to a possible term adjustment period). Pieris AG also holds an exclusive license to an issued U.S. patent No. 8,420,051, which patent is expected to expire in 2029. The Company bears the costs of filing, prosecution and maintenance of patents assigned or licensed to the Company under the agreement. As consideration for the assigned patents and licenses above, the Company is required to pay certain development milestones to TUM. The Company also is obliged to pay low-single-digit royalties, including annual minimum royalties, on sales of such products incorporating patented technologies. If the Company grants licenses or sublicenses to those patents to third parties, the Company will be obliged to pay a percentage of the resulting revenue to TUM. The Company’s payment obligations are reduced by the Company’s proportionate contribution to a joint invention. Payment obligations terminate on expiration or annulment of the last patent covered by the agreement. The Company can terminate the licenses to any or all licensed patents upon specified advance notice to TUM. TUM may terminate the license provisions of the agreement only for cause. Termination of the agreement does not terminate the rights in patents assigned to the Company. The Company has incurred the following expenses related to TUM (excluding value added taxes): Three months ended June 30, Six months ended 2015 2014 2015 2014 Transfer of licenses and protective rights $ 13,836 $ 17,145 $ 27,893 $ 34,276 Total expenses incurred with TUM $ 13,836 $ 17,145 $ 27,893 $ 34,276 The Company has accrued $302,273 and $370,999 as of June 30, 2015 and 2014, respectively, related to the amounts due under the research and license agreement (see Note 9 Commitments and Contingencies The part of the agreement requiring the Company to make payments for research conducted by TUM expired in February 2013 with no further obligations by Pieris AG. Consulting Contract between Prof. Dr. Arne Skerra and Pieris AG In 2001, the Company entered into a Consulting Agreement with Prof. Dr. Arne Skerra, pursuant to which Prof. Dr. Arne Skerra provides advice regarding the use of new proteins, in particular Anticalin® proteins and antibodies, for the purpose of research and development. The Consulting Agreement has an unlimited term but can be terminated by the Company upon three months’ notice with effect from the end of a month and by Prof. Dr. Arne Skerra upon one year’s notice with effect from the end of a year. Under the Consulting Agreement, the Company incurred and paid to Prof. Dr. Skerra consulting fees of $11,157 and $13,711 for the six months ended June 30, 2015 and 2014, respectively. For the three months ended June 30, 2015 and 2014 the Company incurred and paid Prof. Dr. Skerra consulting fees of $5,534 and $6,858, respectively. |
Debt
Debt | 6 Months Ended |
Jun. 30, 2015 | |
Debt Disclosure [Abstract] | |
Debt | 5. Debt TBG Loan As of April 3, 2014, the Company and tbg Technologie-Beteiligungs-Gesellschaft mbH (“TBG”), the subsidiary of KfW Bank, Frankfurt (“KfW”), signed a repayment agreement concerning the Company’s repayment of its liabilities to TBG outstanding at December 31, 2013 in a total amount of €1.2 million ($1.34 million). The principal amount bore interest at a rate of 10.53%. Under the repayment agreement, the Company has agreed to a payment schedule pursuant to which it will make semi-annual payments until 2016. On December 11, 2014, the Company and TBG entered into an accelerated repayment agreement in respect of the claims of TBG against the Company. Pursuant to terms of the accelerated repayment agreement, conditioned upon closing of the Acquisition, the Company was obligated to pay €1,050,000 ($1.17 million), the outstanding amount under the repayment agreement, in two tranches as follows: €600,000 ($669,240) plus accrued interest on January 31, 2015 and €450,000 ($501,930) on March 31, 2015. The outstanding principal amount for the first and the second tranches, net of capital gain tax withheld, was repaid in full in the first quarter ending March 31, 2015 in the amount of €931,312 ($1,038,785). The capital gain tax withheld in the amount of €118,688 ($132,385) was paid on April 9, 2015 and with that the TBG loan was repaid in full. |
Accrued expenses
Accrued expenses | 6 Months Ended |
Jun. 30, 2015 | |
Payables and Accruals [Abstract] | |
Accrued expenses | 6. Accrued expenses The Company has recorded the following accrued expenses as of June 30, 2015 and December 31, 2014, respectively: June 30, December 31, Accrued expenses Accrued compensation expense $ 333,979 $ 332,892 Accrued audit and tax expenses 148,500 403,450 Other accrued expenses 153,082 7,523 Total accrued expenses, current 635,561 743,865 Accrued expenses non-current Reserve for litigation TUM 302,273 327,937 Accrued expenses restoration 5,577 6,051 Total accrued expenses, non-current 307,850 333,988 Total accrued expenses $ 943,411 $ 1,077,853 |
Stock-based compensation
Stock-based compensation | 6 Months Ended |
Jun. 30, 2015 | |
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] | |
Stock-based compensation | 7. Stock-based compensation In December 2014, the Board of Directors and stockholders of Pieris Pharmaceuticals, Inc. adopted the 2014 Employee, Director and Consultant Equity Incentive Plan (the “Pieris Plan”), which became effective upon closing of the Acquisition. The Pieris Plan is intended to encourage ownership of common stock by the Company’s employees and directors and certain of their consultants, including employees of Pieris AG, in order to attract and retain such people, to induce them to work for the benefit of the Company and to provide additional incentive for them to promote the Company’s success. The Pieris Plan reserves 3,200,000 shares of the Company´s common stock for issuance. In addition, the Pieris Plan provides for an “evergreen” provision whereby the number of shares of the Company´s common stock reserved for issuance under the Pieris Plan shall be automatically increased on January 1 of each of year commencing in fiscal 2016 by the lesser of (i) 1,000,000 shares, (ii) 4% of the number of shares of the Company´s common stock outstanding on such date, and (iii) such other amount determined by the Compensation committee of the Board of Directors. As of June 30, 2015, options to purchase 1,470,235 shares of the Company´s common stock are outstanding under the Pieris Plan to its executive officers and directors. 40,235 of these shares were granted during the second quarter of 2015. All other shares were granted in the fourth quarter of 2014. In addition, options to purchase 1,146,500 shares are outstanding under the Pieris Plan to other employees and consultants. 25,000 of these shares were granted during the first quarter of 2015, 32,000 of these shares were granted during the second quarter of 2015 and 1,089,500 were granted during the fourth quarter of 2014. As a result of such grants, 583,265 of the Company´s common stock remain available for future issuances under the Pieris Plan. Stock options granted under the Pieris Plan may be either incentive stock options (“ISOs”), or nonqualified stock options. The Board of Directors determines who will receive options, the vesting periods (which are generally three years) and the exercise prices. Options have a maximum term of ten years. The exercise price of stock options granted under the Pieris Plan must be at least equal to the fair market value of the common stock on the date of grant. The Pieris Plan become effective in December 2014, therefore there was no stock-based compensation expense in the three and six months ended June 30, 2014. Total stock-based compensation expense, related to all share-based awards under the Pieris Plan to executive officers, directors, employees and consultants recognized for the three and six months ended June 30, 2015, was comprised of the following: Three months ended Six months ended June 30, 2015 June 30, 2015 Research and Development $ 78,551 $ 129,590 General and administrative 189,488 355,785 Total stock-option expense $ 268,039 $ 485,375 The fair value of option grants was estimated using the Black-Scholes model. The following table describes the weighted-average assumptions used for calculating the value of options granted for the three and six months ended June 30, 2015: Three months ended Six months ended June 30, 2015 June 30, 2015 Forfeiture rate 6.0 % 6.0 % Dividend yield 0.0 % 0.0 % Expected volatility 73.7 % 74.1 % Weighted average risk-free interest rate 1.73 % 1.71 % Expected term 5.3 - 5.8 years 5.3 - 5.8 years A summary of the Company’s stock option activity and related information is as follows: Number of Weighted- Weighted- Outstanding at December 31, 2014 2,519,500 $ 2.00 5.6 - 5.8 years Options granted 25,000 $ 2.85 5.8 years Options exercised — — — Options cancelled or expired — — — Outstanding at March 31, 2015 2,544,500 $ 2.01 5.6 - 5.8 years Options granted 72,235 $ 2.89 5.3 - 5.8 years Options exercised — $ — — Options cancelled or expired — $ — — Outstanding at June 30, 2015 2,616,735 $ 2.03 5.3 - 5.8 years Vested at June 30, 2015 799,068 $ 2.03 — Expected to vest after June 30,2015 1,708,607 $ 2.03 — Exercisable at June 30, 2015 799,068 $ 2.03 — The weighted-average grant date fair value for awards granted during the three and six months ended June 30, 2015 was $130,456 and $176,898, respectively. There were no options exercised during the three and six months ended June 30, 2015 and 2014. 200,673 and 375,319 shares were vested in the three and six months ended June 30, 2015, respectively. The unrecognized share-based compensation expense related to employee stock option awards at June 30, 2015, is $2,253,478, which will be recognized over a weighted-average service period of 2.5 years. |
Consulting Shares
Consulting Shares | 6 Months Ended |
Jun. 30, 2015 | |
Equity [Abstract] | |
Consulting Shares | 8. Consulting Shares On March 6, 2015, the Company entered into an independent consulting agreement (the “Consulting Agreement”) with the Del Mar Consulting Group, Inc. and Alex Partners, LLC (the “Consultants”), pursuant to which the Company issued 150,000 restricted shares of its common stock (par value $0.01 per share) to the Consultants (the “Consulting Shares”). The Company agreed to retain the Consultants to provide investor relations consulting to the Company for a period commencing on March 6, 2015 (the “Commencement Date”) and ending thirteen months after the Commencement Date (such period, the “Term”). The shares issued in connection with the Consulting Agreement were deemed to be exempt from registration in reliance upon Section 4(a)(2) of the Securities Act as a transaction by an issuer not involving any public offering. The terms of the Consulting Agreement state, that the Company has the right to terminate this agreement at any time during the Term of the Consulting Agreement, upon providing Consultants ten days’ written notice of Company’ intention to terminate or immediately upon notice in the event of a breach of this agreement by either consultant. If the Company delivers notice to terminate this agreement for any reason within one hundred eighty days (180) following the effective date (the “Return Date”), then each Consultant will promptly return and surrender to the Company forty percent (40%) of the number of Consulting Shares issued to it. Therefore 60,000 of these shares are subject to certain forfeiture provisions within 180 days following the date of entry into the Consulting Agreement. The Company, using the Black-Scholes method, estimated the fair value of the 90,000 non-cancellable Consulting Shares to be $284,400 based on the closing price per share of $3.16 as quoted on the OTCQB tier of the OTC Markets Group Inc., or the OTCQB, on the grant date, March 6, 2015. The Company estimated the fair value of the 60,000 cancellable Consulting Shares to be $192,000 based on the closing price per share of $3.20 as quoted on the OTCQB on the interim financial reporting date, March 31, 2015. Therefore, the Company estimated the total fair value of the Consulting Shares to be $476,400 and recognized the 90,000 vested non-cancellable Consulting Shares, or sixty percent (60%) of the Consulting Shares in an amount of $284,400, as general and administrative expense for the six months ended June 30, 2015. The remaining forty percent (40%), or 60,000 Consulting Shares in the amount of $192,000, will be recognized as general and administrative expenses with an offsetting credit to equity on a straight-line basis over 180 days. If the Company exercises the option to terminate the Consulting Agreement within the 180 days, resulting in the cancellation of forty percent (40%) of the Consulting Shares, expense for cancelled, unvested shares will be reversed. On June 30, 2015 the Company revalued the fair value of the unvested and forfeitable 40% of the shares. As of June 30, 2015 the estimated fair value of the 60,000 unvested and forfeitable shares was $165,000. Therefore the Company recognized expenses in connection with the Consulting Shares of $79,666 in general and administrative expenses for the cancellable Consulting Shares during the three months ended June 30, 2015. For the six months ended June 30, 2015 the Company recognized $390,733 in general and administrative expenses, including $284,400 for the non-cancellable Consulting Shares and $106,333 for the cancellable shares. |
Warrants
Warrants | 6 Months Ended |
Jun. 30, 2015 | |
Accounting Changes and Error Corrections [Abstract] | |
Warrants | 9. Warrants In connection with the Private Placement in December 2014, the Company issued the Placement Warrants to acquire combined up to 542,360 shares of its common stock at an exercise price of two dollars per share ($2.00) to the Placement Agents and their designees during December 2014. The Placement Warrants are exercisable at any time at the option of the holder until the five year anniversary of its date of issuance. The number of shares of common stock issuable upon the exercise of each Placement Warrant is adjustable in the event of certain stock dividends, stock splits, combinations of shares and similar transactions. Upon exercise, the aggregate exercise price of the warrants issued are payable by the holders in cash. The Company estimated the fair value of the Placement Warrants as of the grant date to be $664,064 and recognized the full amount in general and administrative expense for the year ended December 31, 2014. |
Commitments and Contingencies
Commitments and Contingencies | 6 Months Ended |
Jun. 30, 2015 | |
Commitments and Contingencies Disclosure [Abstract] | |
Commitments and Contingencies | 10. Commitments and Contingencies Arbitration On March 20, 2014, the Company instituted arbitration proceedings, or the TUM Arbitration, against Technische Universität München, or Munich Technical University and hereafter TUM, to address issues regarding the calculation of payments due from the Company to TUM under the Company’s Research and Licensing Agreement with TUM, as amended, or the TUM License Agreement. Pursuant to the terms of the TUM License Agreement, the arbitration is proceeding in Munich, Germany and governed by German law, in accordance with the arbitration rules of the Deutsche Institution für Schiedsgerichtsbarkeit. On July 4, 2003, or the Effective Date, the Company and TUM entered into the TUM License Agreement, as superseded and replaced on July 26, 2007, under which TUM has exclusively licensed, or in some cases assigned, to the Company certain intellectual property and know-how that has become part of the Anticalin ® As required by the TUM License Agreement, the Company provided to TUM its calculation of the Out-License Fee owed by the Company to TUM for the period beginning on the Effective Date and ending on December 31, 2012, the Dispute Period, in the amount of $0.4 million excluding value-added tax. TUM has asserted that, under the TUM License Agreement, the Out-License Fee due to TUM for the Dispute Period amounts to $3.4 million excluding value-added tax in the aggregate and has threatened to terminate the TUM License Agreement if the Out-License Fee is not paid. We believe that if TUM sought to terminate the license agreement for cause as a result of this dispute, it would potentially face wrongful termination claims for substantial damages if the arbitration tribunal in the TUM Arbitration sides with Pieris in its final decision regarding the proper amount of the Out-License Fee, but we can provide no assurance regarding the timing, nature or consequences of such decision. The Company instituted the TUM Arbitration to request the arbitration tribunal to hold that the Company’s calculation of the payments owed to TUM is accurate and shall govern all current and future payments due in respect of the Out-License Fee under the TUM License Agreement. The Company has reserved a liability on its balance sheet’s position other long-term liabilities in respect of such payment in the amount of €271,000 ($302,273). An adverse ruling in the TUM Arbitration could have a material adverse effect on the Company’s results of operations and financial condition. In April 2014, TUM argued to the arbitrators that it is not the proper party to be sued under the action for a declaratory arbitration decision brought by the Company in relation to the Research and Licensing Agreement, and that instead, it is the Free State of Bavaria that is the proper respondent to the action. The Company has responded that TUM has capacity to be sued in relation to any disputes arising from and regarding contractual provisions of the Research and Licensing Agreement and is thus also the proper respondent in the action. In accordance with the arbitration rules of the Deutsche Institution für Schiedsgerichtsbarkeit, each party to the arbitration proceeding has appointed one arbitrator and the party-named arbitrators collectively selected the third arbitrator as the chairman of the arbitration panel. On December 1, 2014, TUM filed its statement of defense, maintaining its earlier calculation of the Out-License Fee. On December 23, 2014, TUM filed a counterclaim in the amount of €2,529,400 ($3,060,827) to suspend the statute of limitations on its claims. On January 12, 2015, the Company filed a reply brief in response to TUM’s defense. The arbitration panel held its first hearing in Munich, Germany on January 20, 2015, however the arbitration panel did not come to a conclusion on whether TUM is the proper respondent in the action or on the merits of the case. The panel had previously indicated that it will first decide the issue of whether TUM is the proper respondent in this action. The panel resolved that the value in dispute for both parties’ claims and counterclaims would be fixed at €3,500,000 ($4,235,350), as the calculation of the outstanding Out-Licensing Fee also impacts future payments. On March 3, 2015, the Company submitted a reply brief responding to TUM’s statement of defense and counterclaim. On March 31, 2015, TUM submitted a rebuttal brief. The panel requested that both the Company and TUM indicate to the panel by April 27, 2015 whether proceedings should be stayed as a result of settlement negotiations. On April 27, 2015, the Company submitted a reply brief requesting proceedings to continue without disruption and moving for leave to comment on TUM’s submission. Following an approved extension by the panel for TUM’s submission, TUM submitted its proposal on May 4, 2015, requesting that the panel conduct a mediation hearing and assist the parties in negotiating a settlement. On May 8, 2015, the arbitration tribunal set June 1, 2015 as the deadline for final briefs and offered to schedule another oral hearing in mid-June for the purpose of supporting further settlement negotiations if both parties are in favor of holding a hearing. The Company submitted its brief on June 1, 2015. On June 8, 2015, the arbitration tribunal issued a procedural order indicating they will proceed with the arbitration without another oral hearing. TUM did not file its brief by the June 1 deadline set by the panel, and instead filed another submission on June 23, 2015. In its procedural order issued on the same day, the tribunal panel reserved the right to reject TUM’s new submission based on the content of its brief. The tribunal’s subsequent procedural order of June 25, 2015 provided that the tribunal will close the proceedings on July 10, 2015. The order clarified that any further pleadings or submissions will not be admissible after this date. The Company submitted its final brief on July 10, 2015 to address TUM’s arguments raised in its latest submission to provide the tribunal with an overview its costs incurred in this arbitration proceeding. On the same day, TUM submitted its summary of its costs incurred in this arbitration proceeding and subsequently, on July 23, 2015, filed an additional brief to correct some of its earlier submissions on costs and comment on the Company’s cost overview of July 10, arguing that attorneys’ fees claimed by the Company are disproportionately high. The Company replied to the TUM’s on [August, 7], pointing out that the higher attorneys’ fees are justified and resulted from the Company’s submissions on TUM’s standing to be sued and translation costs are also reimbursable in this case. |
Subsequent Events
Subsequent Events | 6 Months Ended |
Jun. 30, 2015 | |
Subsequent Events [Abstract] | |
Subsequent Events | 11. Subsequent Events Public Offering On July 6, 2015 the Company closed a public offering of an aggregate of 9,090,909 shares of the Company´s common stock at a purchase price of $2.75 per share. All shares of common stock were offered by the Company. On July 24, 2015 the underwriters exercised their over-allotment option to purchase 1,211,827 additional shares of the Company’s common stock at the public offering price of $2.75, which sale closed on July 28, 2015. Gross proceeds raised by the Company in the offering, including the exercise of the over-allotment option, were $28.3 million and net proceeds are expected to be approximately $25.8 million. The Company intends to use the net proceeds from the offering to fund research and development, including preclinical and clinical research and development of its drug candidates, working capital and general corporate purposes. Milestone payment On July 8, 2015 the Company announced that it will receive its third milestone payment for the second program in its discovery and development collaboration with Daiichi Sankyo, and seventh milestone payment overall under the multi program collaboration. The amount of payment was not disclosed due to the confidential treatment of this agreement. The payment was triggered by the achievement of positive in vivo Cooperation Agreement On July, 14 the Company entered into a Cooperation Agreement (the “Cooperation Agreement”) with the University of Cologne. The University of Cologne provides research services to the Company for which it will receive up to two milestone payments. For the research services under Milestone 1, the Company shall pay the University a net amount of $48,698 (€43.660) in two installments. Within thirty days following achievement of Milestone 1, the Company and University shall mutually agree whether to continue with the Cooperation Project. Having agreed on continuing with Milestone 2, the Company shall pay the University a net amount of $130,301 (€116,820) in two installments. |
Basis of Presentation and Sum18
Basis of Presentation and Summary of Significant Accounting Policies (Policies) | 6 Months Ended |
Jun. 30, 2015 | |
Accounting Policies [Abstract] | |
Basis of Consolidation | Basis of Consolidation The accompanying unaudited condensed consolidated financial statements of Pieris Pharmaceuticals Inc. and its wholly owned subsidiaries were prepared in accordance with accounting principles generally accepted in the United States (“U.S. GAAP”) for interim financial information. All significant intercompany balances and transactions have been eliminated in the consolidation. Certain information and footnotes normally included in financial statement prepared in accordance with U.S. GAAP have been omitted pursuant to the Securities and Exchange Commission rules and regulations. Accordingly, they do not include all of the information and notes required by U.S. GAAP for complete annual consolidated financial statements. In the opinion of management, the unaudited interim condensed consolidated financial statements have been prepared on the same basis as the audited condensed consolidated financial statements for the year ending December 31, 2014, and all adjustments, including normal recurring adjustments, considered necessary for a fair presentation of Pieris Pharmaceuticals, Inc.’s unaudited interim consolidated financial statements have been included. The results of operations for the three and six months ended June 30, 2015 are not necessarily indicative of the results that may be expected for the year ending December 31, 2015 or any future period. |
Use of estimates | Use of estimates The preparation of the condensed consolidated financial statements in accordance with U.S. GAAP requires management to make estimates, judgments and assumptions that affect the reported amounts of assets and liabilities, the reported amounts of revenues and expenses in the financial statements and disclosures in the accompanying notes. Actual results and outcomes could differ materially from management’s estimates, judgments and assumptions. |
Segment Reporting | Segment Reporting Pieris Pharmaceuticals, Inc. operates as a single segment dedicated to the discovery and development of biotechnological applications and the Company’s chief operating decision maker (CODM) makes decisions based on the Company as a whole. Accordingly, Pieris Pharmaceuticals, Inc. operates and makes decisions as one reporting unit. |
Milestone Payments and Royalties | Milestone Payments and Royalties At the inception of each agreement that includes milestone payments, Pieris Pharmaceuticals, Inc. evaluates whether each milestone is substantive and at risk to both parties on the basis of the contingent nature of the milestone. This evaluation includes an assessment of whether (a) the consideration is commensurate with either (1) the entity’s performance to achieve the milestone, or (2) the enhancement of the value of the delivered item(s) as a result of a specific outcome resulting from the entity’s performance to achieve the milestone, (b) the consideration relates solely to past performance and (c) the consideration is reasonable relative to all of the deliverables and payment terms within the arrangement. Pieris Pharmaceuticals, Inc. evaluates factors such as the scientific, regulatory, commercial and other risks that must be overcome to achieve the respective milestone, the level of effort and investment required to achieve the respective milestone and whether the milestone consideration is reasonable relative to all deliverables and payment terms in the arrangement in making this assessment. Pieris Pharmaceuticals, Inc. aggregates milestones into three categories (i) research milestones, (ii) development milestones and (iii) commercial milestones. Research milestones are typically achieved upon reaching certain success criteria as defined in each agreement related to developing an Anticalin protein against the specified target. Development milestones are typically reached when a compound reaches a defined phase of clinical research or passes such phase, or upon gaining regulatory approvals. Commercial milestones are typically achieved when an approved pharmaceutical product reaches the status for commercial sale or certain defined levels of net sales by the licensee, such as when a product first achieves global sales or annual sales of a specified amount. For revenues from research and development milestone payments, if the milestones are deemed substantive and the milestone payments are nonrefundable, such amounts are recognized entirely upon successful accomplishment of the milestones. Milestones that are not considered substantive are accounted for as license payments and recognized on a straight-line basis over the period of performance. To date, Pieris Pharmaceuticals, Inc. has determined all milestones are substantive. Revenues from commercial milestone payments are accounted for as royalties and are recorded as revenue upon achievement of the milestone, assuming all other revenue recognition criteria are met. Royalty payments are recognized in revenues based on the timing of royalty payments earned in accordance with the agreements; which typically is the period when the relevant sales occur, assuming all other revenue recognition criteria are met. |
Fair Value Measurement | Fair Value Measurement ASC Topic 820 Fair Value Measurement Level 1 inputs are quoted prices in active markets for identical assets or liabilities that the reporting entity has the ability to access at the measurement date. Level 2 utilizes quoted market prices in markets that are not active, broker or dealer quotations, or alternative pricing sources with reasonable levels of price transparency. Level 3 inputs are unobservable inputs for the asset or liability in which there is little, if any, market activity for the asset or liability at the measurement date. Cash equivalents recorded by Pieris Pharmaceuticals, Inc. consist of highly liquid money market funds and are measured at fair value on a recurring basis. These funds are classified as Level 1 in the fair value hierarchy because they are valued using quoted prices for the periods ended June 30, 2015 and December 31, 2014. The carrying amounts of $78,403 and $ 4,800,573 as of June 30, 2015 and December 31, 2014, respectively, equal the fair value of the cash equivalents. The Company’s other financial instruments include debt instruments, prepaid expenses, other current assets, accounts payable, accrued expenses and other current liabilities and are classified as Level 2 within the fair value hierarchy. The fair value of these instruments was determined using the discounted cash flow method based on contractual cash flows and the current rate at which debt with similar terms could be issued. The fair values for these debt instruments approximated carrying values as of June 30, 2015 and December 31, 2014. |
Income taxes | Income taxes Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases, and operating losses and tax credit carry forwards. Deferred tax assets and liabilities are measured using enacted statutory tax rates expected to apply to taxable income in the jurisdictions and years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. Based on the level of historical operating results and projections for the taxable income for the future, the Company has determined that it is more likely than not that the deferred tax assets will not be realized. Accordingly, the Company has recorded a valuation allowance to reduce deferred tax assets to the same amount as deferred tax liabilities and determines an effective tax rate of zero percent. |
Recent Accounting Pronouncements | Recent Accounting Pronouncements In May 2014, the FASB issued ASU No. 2014-09, “Revenue from Contracts with Customers,” (ASU 2014-09) which provides guidance for revenue recognition. The standard’s core principle is that a company will recognize revenue when it transfers promised goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for those goods or services. The new guidance is effective for annual reporting periods beginning after December 15, 2016, including interim periods within that reporting period. Early application is not permitted. On April 1, 2015 the FASB voted in favor of proposing a one year delay of the effective date and to permit companies to voluntarily adopt the new standard as of the original effective date. The Company is currently assessing the potential impact the adoption of this standard will have on their financial statements. In January 2015, the FASB issued ASU No. 2015-01, “Income Statement – Extraordinary and Unusual items” In February 2015, the FASB issued ASU No. 2015-02, “Consolidation (Topic 810): Amendments to the Consolidation Analysis” In June 2015, the FASB issued ASU No. 2015-10, “Technical Corrections and Improvements” (ASU 2015-10). The amendments in ASU 2015-10 represent changes to clarify the FASB Accounting Standards Codification (the “Codification”), correct unintended application of guidance, or make minor improvements to the Codification that are not expected to have a significant effect on current accounting practice or create a significant administrative cost to most entities. In addition, some of the amendments are intended to make the Codification easier to understand and easier to apply by eliminating inconsistencies, providing needed clarifications, and improving the presentation of guidance in the Codification. This guidance is effective for fiscal years, and interim periods within those fiscal years, beginning after December 15, 2015. The company is currently evaluating the impact of this new standard. Pieris Pharmaceuticals, Inc. has considered other recent accounting pronouncements and concluded that they are either not applicable to the business, or that the effect is not expected to be material to the unaudited condensed consolidated financial statements as a result of future adoption. |
Related-Party Transactions (Tab
Related-Party Transactions (Tables) | 6 Months Ended |
Jun. 30, 2015 | |
Related Party Transactions [Abstract] | |
Related Party Expenses | The Company has incurred the following expenses related to TUM (excluding value added taxes): Three months ended June 30, Six months ended 2015 2014 2015 2014 Transfer of licenses and protective rights $ 13,836 $ 17,145 $ 27,893 $ 34,276 Total expenses incurred with TUM $ 13,836 $ 17,145 $ 27,893 $ 34,276 |
Accrued expenses (Tables)
Accrued expenses (Tables) | 6 Months Ended |
Jun. 30, 2015 | |
Payables and Accruals [Abstract] | |
Schedule of Accrued Expenses | The Company has recorded the following accrued expenses as of June 30, 2015 and December 31, 2014, respectively: June 30, December 31, Accrued expenses Accrued compensation expense $ 333,979 $ 332,892 Accrued audit and tax expenses 148,500 403,450 Other accrued expenses 153,082 7,523 Total accrued expenses, current 635,561 743,865 Accrued expenses non-current Reserve for litigation TUM 302,273 327,937 Accrued expenses restoration 5,577 6,051 Total accrued expenses, non-current 307,850 333,988 Total accrued expenses $ 943,411 $ 1,077,853 |
Stock-based compensation (Table
Stock-based compensation (Tables) | 6 Months Ended |
Jun. 30, 2015 | |
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] | |
Schedule of Total Stock-Based Compensation Expense Related to Share-Based Awards under the Pieris Plan | Total stock-based compensation expense, related to all share-based awards under the Pieris Plan to executive officers, directors, employees and consultants recognized for the three and six months ended June 30, 2015, was comprised of the following: Three months ended Six months ended June 30, 2015 June 30, 2015 Research and Development $ 78,551 $ 129,590 General and administrative 189,488 355,785 Total stock-option expense $ 268,039 $ 485,375 |
Schedule of Weighted-Average Assumptions Used for Calculating Value of Options Granted | The fair value of option grants was estimated using the Black-Scholes model. The following table describes the weighted-average assumptions used for calculating the value of options granted for the three and six months ended June 30, 2015: Three months ended Six months ended June 30, 2015 June 30, 2015 Forfeiture rate 6.0 % 6.0 % Dividend yield 0.0 % 0.0 % Expected volatility 73.7 % 74.1 % Weighted average risk-free interest rate 1.73 % 1.71 % Expected term 5.3 - 5.8 years 5.3 - 5.8 years |
Schedule of Information Regarding Stock Option Activity | A summary of the Company’s stock option activity and related information is as follows: Number of Weighted- Weighted- Outstanding at December 31, 2014 2,519,500 $ 2.00 5.6 - 5.8 years Options granted 25,000 $ 2.85 5.8 years Options exercised — — — Options cancelled or expired — — — Outstanding at March 31, 2015 2,544,500 $ 2.01 5.6 - 5.8 years Options granted 72,235 $ 2.89 5.3 - 5.8 years Options exercised — $ — — Options cancelled or expired — $ — — Outstanding at June 30, 2015 2,616,735 $ 2.03 5.3 - 5.8 years Vested at June 30, 2015 799,068 $ 2.03 — Expected to vest after June 30,2015 1,708,607 $ 2.03 — Exercisable at June 30, 2015 799,068 $ 2.03 — |
Corporate Information - Additio
Corporate Information - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands | Dec. 23, 2014 | Dec. 31, 2014 |
Organization And Description Of Business [Line Items] | ||
Exercise price of warrants | $ 2 | $ 2 |
Warrant exercisable period | 5 years | 5 years |
Private Placement [Member] | ||
Organization And Description Of Business [Line Items] | ||
Stock issued | 6,779,510 | |
Sales of common stock, price per share | $ 2 | |
Proceeds from sale of stock | $ 13,560 | |
Common Stock [Member] | ||
Organization And Description Of Business [Line Items] | ||
Aggregate shares issued upon acquisition | 542,360 |
Basis of Presentation and Sum23
Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Detail) | 6 Months Ended | |
Jun. 30, 2015USD ($)Segment | Dec. 31, 2014USD ($) | |
Summary Of Significant Accounting Policies [Line Items] | ||
Number of Operating segment | Segment | 1 | |
Milestones arrangement, categories description | Pieris Pharmaceuticals, Inc. aggregates milestones into three categories (i) research milestones, (ii) development milestones and (iii) commercial milestones. | |
Effective tax rate | 0.00% | |
Fair Value, Inputs, Level 1 [Member] | ||
Summary Of Significant Accounting Policies [Line Items] | ||
Cash and Cash Equivalents, Fair Value | $ 78,403 | $ 4,800,573 |
Revenues - Additional Informati
Revenues - Additional Information (Detail) - USD ($) | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended | ||||||
May. 31, 2011 | Sep. 30, 2010 | Aug. 31, 2009 | Jun. 30, 2015 | Jun. 30, 2014 | Jun. 30, 2015 | Jun. 30, 2014 | Dec. 31, 2012 | Dec. 31, 2011 | Feb. 28, 2013 | |
Deferred Revenue Arrangement [Line Items] | ||||||||||
Revenues from product sales | $ 0 | |||||||||
Collaborative Arrangement [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | $ 400,000 | 0 | $ 400,000 | |||||||
Allergan Inc [Member] | Collaborative Arrangement [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 0 | |||||||||
Allergan Inc [Member] | Collaborative Arrangement [Member] | Maximum [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | $ 13,000,000 | 13,000,000 | ||||||||
Allergan Inc [Member] | Collaborative Arrangement [Member] | Upfront Payment Arrangement [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, license revenue | $ 10,000,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 0 | 0 | 0 | 300,000 | ||||||
Collaboration agreement, revenue recognized | 0 | 200,000 | $ 0 | 700,000 | ||||||
Description of factors in determining milestones substantive | Factors considered in determining the options were substantive were whether (i) Sanofi could obtain the overall objective of the agreement without exercising any options, (ii) Sanofi was able to obtain value from the initial licenses obtained without exercising any options, (iii) the cost to exercise the options was significant relative to the total upfront payment of $4.9 million for two licenses and four options, and (iv) exercising the option created additional financial commitments for Sanofi or imposed economic penalties on Sanofi. | |||||||||
Collaborative arrangement, consideration | $ 8,100,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Expired Option Agreement [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, revenue recognized | $ 700,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Options Exercised [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, revenue recognized | $ 350,000 | |||||||||
Collaborative arrangement, consideration | $ 280,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Options, Exercised Price [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaborative arrangement, consideration | $ 1,100,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Licenses [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaborative arrangement, consideration | 3,500,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Options to Acquire Additional Licenses [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaborative arrangement, consideration | 1,400,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Research Services [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Research collaboration agreement, estimated period | 2 years | |||||||||
Collaborative arrangement, consideration | 3,200,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Research Services [Member] | Extension Term [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Research collaboration agreement, estimated period | 40 months | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Maximum [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 51,600,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Maximum [Member] | Research Milestones [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 1,900,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Maximum [Member] | Development Milestones [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 29,600,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Maximum [Member] | Commercial Milestones [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 20,100,000 | |||||||||
Sanofi [Member] | Collaborative Arrangement [Member] | Upfront Payment Arrangement [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, license revenue | $ 4,900,000 | |||||||||
Daiichi Sankyo Inc [Member] | Collaborative Arrangement [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Research collaboration agreement, estimated period | 2 years | |||||||||
Collaboration agreement, revenue recognized | $ 0 | $ 400,000 | $ 0 | $ 1,100,000 | ||||||
Daiichi Sankyo Inc [Member] | Collaborative Arrangement [Member] | Maximum [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | $ 91,100,000 | |||||||||
Daiichi Sankyo Inc [Member] | Collaborative Arrangement [Member] | Maximum [Member] | Research Milestones [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 2,600,000 | |||||||||
Daiichi Sankyo Inc [Member] | Collaborative Arrangement [Member] | Maximum [Member] | Development Milestones [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 37,400,000 | |||||||||
Daiichi Sankyo Inc [Member] | Collaborative Arrangement [Member] | Maximum [Member] | Commercial Milestones [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 50,200,000 | |||||||||
Daiichi Sankyo Inc [Member] | Collaborative Arrangement [Member] | Maximum [Member] | Additional Diagnostic Milestones [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, milestone payments | 900,000 | |||||||||
Daiichi Sankyo Inc [Member] | Collaborative Arrangement [Member] | Upfront Payment Arrangement [Member] | ||||||||||
Deferred Revenue Arrangement [Line Items] | ||||||||||
Collaboration agreement, license revenue | $ 10,100,000 |
Related Party Transaction - Add
Related Party Transaction - Additional Information (Detail) - USD ($) | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2015 | Jun. 30, 2014 | Jun. 30, 2015 | Jun. 30, 2014 | |
Patent No. 8,420,051 [Member] | ||||
Related Party Transaction [Line Items] | ||||
Expected patent expiration year | 2,029 | |||
Consulting Agreement [Member] | ||||
Related Party Transaction [Line Items] | ||||
Consulting agreement fees paid to Prof. Dr. Skerra | $ 5,534 | $ 6,858 | $ 11,157 | $ 13,711 |
TUM [Member] | ||||
Related Party Transaction [Line Items] | ||||
Patent expiration year | 2,027 | |||
TUM [Member] | License Agreement [Member] | ||||
Related Party Transaction [Line Items] | ||||
Contingent accrual liability for research and licensing agreement | $ 302,273 | $ 370,999 | $ 302,273 | $ 370,999 |
Related-Party Transactions - Re
Related-Party Transactions - Related Party Expenses (Detail) - TUM [Member] - USD ($) | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2015 | Jun. 30, 2014 | Jun. 30, 2015 | Jun. 30, 2014 | |
Related Party Transaction [Line Items] | ||||
Transfer of licenses and protective rights | $ 13,836 | $ 17,145 | $ 27,893 | $ 34,276 |
Total expenses | $ 13,836 | $ 17,145 | $ 27,893 | $ 34,276 |
Debt - Additional Information (
Debt - Additional Information (Detail) - Tbg [Member] | Dec. 11, 2014USD ($)Tranches | Jun. 30, 2015USD ($) | Jun. 30, 2015EUR (€) | Mar. 31, 2015USD ($) | Mar. 31, 2015EUR (€) | Jan. 31, 2015USD ($) | Jan. 31, 2015EUR (€) | Dec. 11, 2014EUR (€) | Apr. 03, 2014USD ($) | Apr. 03, 2014EUR (€) |
Debt Instrument [Line Items] | ||||||||||
Amount of repayment to TBG outstanding | $ 1,170,000 | € 1,050,000 | $ 1,340,000 | € 1,200,000 | ||||||
Principal amount, interest rate | 10.53% | 10.53% | ||||||||
Repayment agreement description | Under the repayment agreement, the Company has agreed to a payment schedule pursuant to which it will make semi-annual payments until 2016. | Under the repayment agreement, the Company has agreed to a payment schedule pursuant to which it will make semi-annual payments until 2016. | ||||||||
Capital gain tax withheld | $ 132,385 | € 118,688 | ||||||||
Number of tranches | 2 | |||||||||
Repayment amount of debt | $ 1,038,785 | € 931,312 | ||||||||
Debt Instrument, Redemption, Period One [Member] | ||||||||||
Debt Instrument [Line Items] | ||||||||||
Amount of repayment to TBG outstanding | $ 669,240 | € 600,000 | ||||||||
Debt Instrument, Redemption, Period Two [Member] | ||||||||||
Debt Instrument [Line Items] | ||||||||||
Amount of repayment to TBG outstanding | $ 501,930 | € 450,000 |
Accrued Expenses - Schedule of
Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($) | Jun. 30, 2015 | Dec. 31, 2014 |
Accrued expenses | ||
Accrued compensation expense | $ 333,979 | $ 332,892 |
Accrued audit and tax expenses | 148,500 | 403,450 |
Other accrued expenses | 153,082 | 7,523 |
Total accrued expenses, current | 635,561 | 743,865 |
Accrued expenses non-current | ||
Reserve for litigation TUM | 302,273 | 327,937 |
Accrued expenses restoration | 5,577 | 6,051 |
Total accrued expenses, non-current | 307,850 | 333,988 |
Total accrued expenses | $ 943,411 | $ 1,077,853 |
Stock-based Compensation - Addi
Stock-based Compensation - Additional Information (Detail) - USD ($) | 3 Months Ended | 6 Months Ended | ||||
Jun. 30, 2015 | Mar. 31, 2015 | Dec. 31, 2014 | Jun. 30, 2014 | Jun. 30, 2015 | Jun. 30, 2014 | |
Stock Based Compensation [Line Items] | ||||||
Number of shares, Options outstanding | 2,616,735 | 2,544,500 | 2,519,500 | 2,616,735 | ||
Number of shares, Options granted | 72,235 | 25,000 | ||||
Share-based payment award, award vesting period | 3 years | |||||
Maximum term of stock options | 10 years | |||||
Weighted average grant date fair value | $ 130,456 | $ 176,898 | ||||
Number of shares, Options exercised | 0 | 0 | 0 | 0 | 0 | |
Options vested | 200,673 | 375,319 | ||||
Unrecognized share-based compensation expense | $ 2,253,478 | $ 2,253,478 | ||||
Recognized weighted average service period | 2 years 6 months | |||||
Pieris Plan [Member] | ||||||
Stock Based Compensation [Line Items] | ||||||
Common stock reserved for issuance | 3,200,000 | |||||
Share-based compensation description | (i) 1,000,000 shares, (ii) 4% of the number of shares of the Company's common stock outstanding on such date, and (iii) such other amount determined by the Compensation committee of the Board of Directors. As of June 30, 2015, options to purchase 1,470,235 shares of the Company's common stock are outstanding under the Pieris Plan to its executive officers and directors. 40,235 of these shares were granted during the second quarter of 2015. All other shares were granted in the fourth quarter of 2014. | |||||
Common stock available for grant | 583,265 | 583,265 | ||||
Pieris Plan [Member] | Executive Officers And Directors [Member] | ||||||
Stock Based Compensation [Line Items] | ||||||
Number of shares, Options outstanding | 1,470,235 | 1,470,235 | ||||
Number of shares, Options granted | 40,235 | |||||
Pieris Plan [Member] | Other Employees and Consultants [Member] | ||||||
Stock Based Compensation [Line Items] | ||||||
Number of shares, Options outstanding | 1,146,500 | 1,146,500 | ||||
Number of shares, Options granted | 32,000 | 25,000 | 1,089,500 |
Stock-based Compensation - Sche
Stock-based Compensation - Schedule of Total Stock-Based Compensation Expense Related to Share-Based Awards under the Pieris Plan (Detail) - Jun. 30, 2015 - USD ($) | Total | Total |
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] | ||
Total stock-option expense | $ 268,039 | $ 485,375 |
Research and Development [Member] | ||
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] | ||
Total stock-option expense | 78,551 | 129,590 |
General and Administrative [Member] | ||
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] | ||
Total stock-option expense | $ 189,488 | $ 355,785 |
Stock-based Compensation - Sc31
Stock-based Compensation - Schedule of Weighted-Average Assumptions Used for Calculating Value of Options Granted (Detail) - Jun. 30, 2015 | Total | Total |
Share-based Compensation Arrangement by Share-based Payment Award, Options Outstanding, Weighted Average Exercise Price, and Additional Disclosures [Abstract] | ||
Forfeiture rate | 6.00% | 6.00% |
Dividend yield | 0.00% | 0.00% |
Expected volatility | 73.70% | 74.10% |
Weighted average risk-free interest rate | 1.73% | 1.71% |
Minimum [Member] | ||
Share-based Compensation Arrangement by Share-based Payment Award, Options Outstanding, Weighted Average Exercise Price, and Additional Disclosures [Abstract] | ||
Expected term | 5 years 3 months 18 days | 5 years 3 months 18 days |
Maximum [Member] | ||
Share-based Compensation Arrangement by Share-based Payment Award, Options Outstanding, Weighted Average Exercise Price, and Additional Disclosures [Abstract] | ||
Expected term | 5 years 9 months 18 days | 5 years 9 months 18 days |
Stock-based Compensation - Sc32
Stock-based Compensation - Schedule of Information Regarding Stock Option Activity (Detail) - $ / shares | 3 Months Ended | 6 Months Ended | 12 Months Ended | |||
Jun. 30, 2015 | Mar. 31, 2015 | Jun. 30, 2014 | Jun. 30, 2015 | Jun. 30, 2014 | Dec. 31, 2014 | |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] | ||||||
Number of shares, Outstanding at beginning balance | 2,544,500 | 2,519,500 | 2,519,500 | |||
Number of shares, Options granted | 72,235 | 25,000 | ||||
Number of shares, Options exercised | 0 | 0 | 0 | 0 | 0 | |
Number of shares, Options cancelled or expired | 0 | 0 | ||||
Number of shares, Outstanding at ending balance | 2,616,735 | 2,544,500 | 2,616,735 | 2,519,500 | ||
Number of shares, Vested | 799,068 | 799,068 | ||||
Number of shares, Expected to vest | 1,708,607 | 1,708,607 | ||||
Number of shares, Exercisable | 799,068 | 799,068 | ||||
Weighted-Average Exercise Price, Outstanding at beginning balance | $ 2.01 | $ 2 | $ 2 | |||
Weighted-Average Exercise Price, Options granted | 2.89 | 2.85 | ||||
Weighted-Average Exercise Price, Options exercised | 0 | 0 | ||||
Weighted-Average Exercise Price, Options cancelled or expired | 0 | 0 | ||||
Weighted-Average Exercise Price, Outstanding ending balance | 2.03 | $ 2.01 | 2.03 | $ 2 | ||
Weighted-Average Exercise Price, Vested | 2.03 | |||||
Weighted-Average Exercise Price, Expected to vest | 2.03 | |||||
Weighted-Average Exercise Price, Exercisable | $ 2.03 | $ 2.03 | ||||
Weighted-Average Contractual Life, Options granted | 5 years 9 months 18 days | |||||
Minimum [Member] | ||||||
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] | ||||||
Weighted-Average Contractual Life, Options granted | 5 years 3 months 18 days | |||||
Weighted-Average Contractual Life, Outstanding | 5 years 7 months 6 days | 5 years 3 months 18 days | 5 years 7 months 6 days | |||
Maximum [Member] | ||||||
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] | ||||||
Weighted-Average Contractual Life, Options granted | 5 years 9 months 18 days | |||||
Weighted-Average Contractual Life, Outstanding | 5 years 9 months 18 days | 5 years 9 months 18 days | 5 years 9 months 18 days |
Consulting Shares - Additional
Consulting Shares - Additional Information (Detail) | 3 Months Ended | 6 Months Ended | |||
Jun. 30, 2015USD ($)$ / sharesshares | Mar. 31, 2015USD ($)$ / sharesshares | Jun. 30, 2015USD ($)$ / sharesshares | Mar. 06, 2015$ / sharesshares | Dec. 31, 2014$ / sharesshares | |
Related Party Transaction [Line Items] | |||||
Common stock, shares issued | shares | 29,429,522 | 29,429,522 | 29,279,522 | ||
Common stock par value of issued shares | $ / shares | $ 0.001 | $ 0.001 | $ 0.001 | ||
Consulting Agreement [Member] | |||||
Related Party Transaction [Line Items] | |||||
Common stock, shares issued | shares | 150,000 | ||||
Common stock par value of issued shares | $ / shares | $ 0.01 | ||||
Agreement termination notice period | 180 days | ||||
Termination agreement percentage of shares returned | 40.00% | ||||
Shares subject to forfeiture | shares | 60,000 | ||||
Estimated fair value of non-cancellable shares, Shares | shares | 90,000 | ||||
Estimated fair value of non-cancellable shares, Value | $ 284,400 | ||||
Estimated fair value cancellable shares, Shares | shares | 60,000 | ||||
Estimated fair value of cancellable shares, Value | $ 192,000 | ||||
Estimated fair value of consulting shares | $ 476,400 | ||||
Percentage of consulting shares recognizable as general and administrative expense | 60.00% | ||||
Percentage of consulting shares recognizable as general and administrative expense offsetting credit to equity | 40.00% | ||||
Revalued unvested and forfeitable shares, percent | 40.00% | ||||
Number of unvested and forfeitable shares for revaluation | 60,000 | ||||
Estimated fair value of unvested and forfeitable shares, Value | $ 165,000 | ||||
General and administrative expense recognized in consulting shares | 390,733 | ||||
Consulting Agreement [Member] | Non Cancellable Shares [Member] | |||||
Related Party Transaction [Line Items] | |||||
Share price | $ / shares | $ 3.16 | ||||
Estimated fair value of consulting shares | 284,400 | ||||
General and administrative expense recognized in consulting shares | 284,400 | ||||
Consulting Agreement [Member] | Cancellable Shares [Member] | |||||
Related Party Transaction [Line Items] | |||||
Share price | $ / shares | $ 3.20 | ||||
Estimated fair value of consulting shares | 192,000 | ||||
General and administrative expense recognized in consulting shares | $ 79,666 | $ 106,333 |
Warrants - Additional Informati
Warrants - Additional Information (Detail) - USD ($) | Dec. 23, 2014 | Dec. 31, 2014 | Dec. 31, 2014 |
Equity [Abstract] | |||
Number of common stock purchased | 542,360 | 542,360 | |
Exercise price of warrants | $ 2 | $ 2 | $ 2 |
Warrant exercisable period | 5 years | 5 years | |
Warrant expense recognized | $ 664,064 |
Commitments and Contingencies -
Commitments and Contingencies - Additional Information (Detail) | Dec. 23, 2014USD ($) | Dec. 23, 2014EUR (€) | Jun. 30, 2015USD ($) | Jun. 30, 2015EUR (€) | Jun. 30, 2015EUR (€) |
Loss Contingencies [Line Items] | |||||
Counterclaim amount filed | $ 3,060,827 | € 2,529,400 | |||
Claims and counterclaims amount | $ 4,235,350 | € 3,500,000 | |||
Out License Fee [Member] | |||||
Loss Contingencies [Line Items] | |||||
Out-License Fee amount | 400,000 | ||||
TUM [Member] | Out License Fee [Member] | |||||
Loss Contingencies [Line Items] | |||||
Out-License Fee amount | 3,400,000 | ||||
Reserved liability | $ 302,273 | € 271,000 |
Subsequent Events - Additional
Subsequent Events - Additional Information (Detail) | Jul. 24, 2015$ / sharesshares | Jul. 14, 2015USD ($) | Jul. 14, 2015EUR (€) | Jul. 06, 2015USD ($)$ / sharesshares | Jun. 30, 2015USD ($)shares | Mar. 31, 2015shares | Jun. 30, 2014USD ($)shares | Jun. 30, 2015USD ($)shares | Jun. 30, 2014USD ($)shares |
Subsequent Event [Line Items] | |||||||||
Number of shares, Options exercised | shares | 0 | 0 | 0 | 0 | 0 | ||||
Research and development expense | $ 1,725,592 | $ 1,118,920 | $ 3,250,222 | $ 2,341,666 | |||||
Subsequent Event [Member] | |||||||||
Subsequent Event [Line Items] | |||||||||
Gross proceeds from issuance initial public offering | $ 28,300,000 | ||||||||
Net proceeds from issuance initial public offering | $ 25,800,000 | ||||||||
Subsequent Event [Member] | Cooperation Agreement [Member] | Milestone One [Member] | |||||||||
Subsequent Event [Line Items] | |||||||||
Research and development expense | $ 48,698 | € 43,660 | |||||||
Subsequent Event [Member] | Cooperation Agreement [Member] | Milestone Two [Member] | |||||||||
Subsequent Event [Line Items] | |||||||||
Research and development expense | $ 130,301 | € 116,820 | |||||||
Subsequent Event [Member] | IPO [Member] | |||||||||
Subsequent Event [Line Items] | |||||||||
Stock issued | shares | 9,090,909 | ||||||||
Sales of common stock, price per share | $ / shares | $ 2.75 | $ 2.75 | |||||||
Number of shares, Options exercised | shares | 1,211,827 |