| Cover - USD ($) $ in Millions | 12 Months Ended | ||
| Dec. 31, 2023 | Mar. 13, 2024 | Jun. 30, 2023 | |
| Cover [Abstract] | |||
| Document Type | 10-K/A | ||
| Amendment Flag | true | ||
| Amendment Description | The purpose of this Amendment No. 2 on Form 10-K/A (the “Amendment”) is to correct errors in Part III, Item 11 – “Executive Compensation” and Item 12 – “Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matter”, of the previously filed Amendment No. 1 on Form 10-K/A of Hepion Pharmaceuticals, Inc. (the “Company”) for the year ended December 31, 2023, filed with the Securities and Exchange Commission (the “SEC”) on June 25, 2024 (the “Amended Form 10-K”). As a result of this Amendment, the Company is also filing the certifications required under Section 302 of the Sarbanes-Oxley Act of 2002 as exhibits to this Amendment. Except as described above, no other changes have been made to the Amended Form 10-K. Among other things, forward-looking statements made in the Amended Form 10-K have not been revised to reflect events that occurred or facts that became known to us after the filing of the Amended Form 10-K, and such forward-looking statements should be read in their historical context. | ||
| Document Annual Report | true | ||
| Document Transition Report | false | ||
| Document Period End Date | Dec. 31, 2023 | ||
| Document Fiscal Period Focus | FY | ||
| Document Fiscal Year Focus | 2023 | ||
| Current Fiscal Year End Date | --12-31 | ||
| Entity File Number | 001-36856 | ||
| Entity Registrant Name | HEPION PHARMACEUTICALS, INC. | ||
| Entity Central Index Key | 0001583771 | ||
| Entity Tax Identification Number | 46-2783806 | ||
| Entity Incorporation, State or Country Code | DE | ||
| Entity Address, Address Line One | 399 Thornall Street | ||
| Entity Address, Address Line Two | First Floor | ||
| Entity Address, City or Town | Edison | ||
| Entity Address, State or Province | NJ | ||
| Entity Address, Postal Zip Code | 08837 | ||
| City Area Code | (732) | ||
| Local Phone Number | 902-4000 | ||
| Title of 12(b) Security | Common Stock, par value $0.0001 per share | ||
| Entity Well-known Seasoned Issuer | No | ||
| Entity Voluntary Filers | No | ||
| Entity Current Reporting Status | Yes | ||
| Entity Interactive Data Current | Yes | ||
| Entity Filer Category | Non-accelerated Filer | ||
| Entity Small Business | true | ||
| Entity Emerging Growth Company | false | ||
| Entity Shell Company | false | ||
| Entity Public Float | $ 40.3 | ||
| Entity Common Stock, Shares Outstanding | 5,473,126 | ||
| Documents Incorporated by Reference [Text Block] | None. | ||
| Document Financial Statement Error Correction [Flag] | false | ||
| Auditor Firm ID | 606 | ||
| Auditor Name | GRASSI & CO., CPAs, P.C. | ||
| Auditor Location | Jericho, New York |
