Cormorant Asset Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
4D MOLECULAR THERAPEUTICS IN	COM	35104E100	8,676	200,000	SH		DFND	1	200,000	0	0
5 01 ACQUISITION CORP	COM CL A	33836P105	4,988	500,000	SH		DFND	1	500,000	0	0
908 DEVICES INC	COM	65443P102	25,919	545,322	SH		DFND	1	545,322	0	0
ACCELERON PHARMA INC	COM	00434H108	37,293	275,000	SH		DFND	1	275,000	0	0
ACLARIS THERAPEUTICS INC	COM	00461U105	50,400	2,000,000	SH		DFND	1	2,000,000	0	0
AGENUS INC	COM NEW	00847G705	21,080	7,750,000	SH		DFND	1	7,750,000	0	0
AKERO THERAPEUTICS INC	COM	00973Y108	21,541	742,549	SH		DFND	1	742,549	0	0
AKOUOS INC	COM	00973J101	6,935	499,989	SH		DFND	1	499,989	0	0
ALBIREO PHARMA INC	COM	01345P106	17,625	500,000	SH		DFND	1	500,000	0	0
ALIGOS THERAPEUTICS INC	COM	01626L105	28,815	1,267,167	SH		DFND	1	1,267,167	0	0
ALLAKOS INC	COM	01671P100	2,870	25,000	SH		DFND	1	25,000	0	0
ALX ONCOLOGY HLDGS INC	COM	00166B105	65,022	881,770	SH		DFND	1	881,770	0	0
ANAPTYSBIO INC	COM	032724106	14,008	650,000	SH		DFND	1	650,000	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	80,075	1,866,108	SH		DFND	1	1,866,108	0	0
APTOSE BIOSCIENCES INC	COM NEW	03835T200	23,900	4,000,000	SH		DFND	1	4,000,000	0	0
ARENA PHARMACEUTICALS INC	COM NEW	040047607	1,388	20,000	SH		DFND	1	20,000	0	0
ARGENX SE	SPONSORED ADR	04016X101	8,262	30,000	SH		DFND	1	30,000	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	12,888	100,000	SH		DFND	1	100,000	0	0
ATEA PHARMACEUTICALS INC	COM	04683R106	395,901	6,411,355	SH		DFND	1	6,411,355	0	0
ATRECA INC	CL A COM	04965G109	4,499	293,500	SH		DFND	1	293,500	0	0
AUTOLUS THERAPEUTICS PLC	SPON ADS	05280R100	2,419	422,167	SH		DFND	1	422,167	0	0
AVEO PHARMACEUTICALS INC	COM NEW	053588307	10,980	1,500,000	SH		DFND	1	1,500,000	0	0
AVIDITY BIOSCIENCES INC	COM	05370A108	53,752	2,464,545	SH		DFND	1	2,464,545	0	0
AXONICS MODULATION TECHNOLOG	COM	05465P101	41,504	693,000	SH		DFND	1	693,000	0	0
AXSOME THERAPEUTICS INC	COM	05464T104	11,324	200,000	SH		DFND	1	200,000	0	0
BCLS ACQUISITION CORP	COM CL A	G0904B105	5,285	500,000	SH		DFND	1	500,000	0	0
BCTG ACQUISITION CORP	COM	05492W103	8,896	800,000	SH		DFND	1	800,000	0	0
BEAM THERAPEUTICS INC	COM	07373V105	13,749	171,775	SH		DFND	1	171,775	0	0
BIOATLA INC	COM	09077B104	109,927	2,192,060	SH		DFND	1	2,192,060	0	0
BIOHAVEN PHARMACTL HLDG CO L	COM	G11196105	13,670	200,000	SH		DFND	1	200,000	0	0
BIONTECH SE	SPONSORED ADS	09075V102	10,919	100,000	SH		DFND	1	100,000	0	0
BLUEPRINT MEDICINES CORP	COM	09627Y109	24,035	247,200	SH		DFND	1	247,200	0	0
BRIDGEBIO PHARMA INC	COM	10806X102	133,605	2,168,909	SH		DFND	1	2,168,909	0	0
C4 THERAPEUTICS INC	COM STK	12529R107	92,107	2,490,065	SH		DFND	1	2,490,065	0	0
CABALETTA BIO INC	COM	12674W109	21,139	1,904,424	SH		DFND	1	1,904,424	0	0
CARDIFF ONCOLOGY INC	COM	14147L108	1,389	150,000	SH		DFND	1	150,000	0	0
CEREVEL THERAPEUTICS HLDNG I	*W EXP 06/09/202	15678U102	563	133,331	SH		DFND	1	133,331	0	0
CHEMOCENTRYX INC	COM	16383L106	43,554	850,000	SH		DFND	1	850,000	0	0
CONNECT BIOPHARMA HLDGS LTD	ADS	207523101	18,500	1,000,000	SH		DFND	1	1,000,000	0	0
CULLINAN ONCOLOGY INC	COM	230031106	6,250	150,000	SH		DFND	1	150,000	0	0
DECIPHERA PHARMACEUTICALS IN	COM	24344T101	8,968	200,000	SH		DFND	1	200,000	0	0
DERMTECH INC	COM	24984K105	40,632	800,000	SH		DFND	1	800,000	0	0
DESIGN THERAPEUTICS INC	COM	25056L103	146,409	5,114,850	SH		DFND	1	5,114,850	0	0
EDGEWISE THERAPEUTICS INC	COM	28036F105	74,307	2,340,914	SH		DFND	1	2,340,914	0	0
EIGER BIOPHARMACEUTICALS INC	COM	28249U105	3,540	400,000	SH		DFND	1	400,000	0	0
ELEDON PHARMACEUTICALS INC	COM	28617K101	15,146	1,415,500	SH		DFND	1	1,415,500	0	0
FATE THERAPEUTICS INC	COM	31189P102	824	10,000	SH		DFND	1	10,000	0	0
FOGHORN THERAPEUTICS INC	COM	344174107	13,180	1,000,000	SH		DFND	1	1,000,000	0	0
FORMA THERAPEUTICS HLDGS INC	SHS	34633R104	132,254	4,720,000	SH		DFND	1	4,720,000	0	0
GALECTO INC	COM	36322Q107	13,066	2,150,732	SH		DFND	1	2,150,732	0	0
GEMINI THERAPEUTICS INC	COM	36870G105	6,436	475,000	SH		DFND	1	475,000	0	0
GENETRON HLDGS LTD	ADS	37186H100	6,438	300,000	SH		DFND	1	300,000	0	0
GOSSAMER BIO INC	COM	38341P102	7,848	848,382	SH		DFND	1	848,382	0	0
GRACELL BIOTECHNOLOGIES INC	SPONSORED ADS	38406L103	1,925	125,000	SH		DFND	1	125,000	0	0
HARPOON THERAPEUTICS INC	COM	41358P106	11,937	570,600	SH		DFND	1	570,600	0	0
HEALTH SCIENCES ACQ CORP 2	ORD SHS	G4411D109	8,984	800,000	SH		DFND	1	800,000	0	0
HELIX ACQUISITION CORP	COM CL A	G4444C102	4,386	430,000	SH		DFND	1	430,000	0	0
HUMANIGEN INC	COM NEW	444863203	19,100	1,000,000	SH		DFND	1	1,000,000	0	0
IGM BIOSCIENCES INC	COM	449585108	38,021	495,769	SH		DFND	1	495,769	0	0
IMMUNOVANT INC	COM	45258J102	5,406	337,048	SH		DFND	1	337,048	0	0
IMV INC	COM	44974L103	772	234,374	SH		DFND	1	234,374	0	0
INSMED INC	COM PAR $.01	457669307	10,218	300,000	SH		DFND	1	300,000	0	0
INSPIRE MED SYS INC	COM	457730109	17,594	85,000	SH		DFND	1	85,000	0	0
INSTIL BIO INC	COM	45783C101	3,762	150,000	SH		DFND	1	150,000	0	0
INTELLIA THERAPEUTICS INC	COM	45826J105	24,075	300,000	SH	Put	DFND	1	300,000	0	0
ISHARES TR	RUSSELL 2000 ETF	464287655	441,880	2,000,000	SH	Put	DFND	1	2,000,000	0	0
ITEOS THERAPEUTICS INC	COM	46565G104	10,254	300,000	SH		DFND	1	300,000	0	0
KADMON HLDGS INC	COM	48283N106	2,918	750,000	SH		DFND	1	750,000	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	19,268	750,000	SH		DFND	1	750,000	0	0
KINIKSA PHARMACEUTICALS LTD	COM CL A	G5269C101	2,406	130,000	SH		DFND	1	130,000	0	0
LONGBOARD PHARMACEUTICALS IN	COM	54300N103	37,193	2,356,000	SH		DFND	1	2,356,000	0	0
MAGENTA THERAPEUTICS INC	COM	55910K108	7,104	600,000	SH		DFND	1	600,000	0	0
MERUS N V	COM	N5749R100	7,311	350,000	SH		DFND	1	350,000	0	0
MINERVA NEUROSCIENCES INC	COM	603380106	584	200,000	SH	��	DFND	1	200,000	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	47,108	275,000	SH		DFND	1	275,000	0	0
MORPHIC HLDG INC	COM	61775R105	22,148	350,000	SH		DFND	1	350,000	0	0
MYOVANT SCIENCES LTD	COM	G637AM102	20,580	1,000,000	SH		DFND	1	1,000,000	0	0
NEKTAR THERAPEUTICS	COM	640268108	400	20,000	SH		DFND	1	20,000	0	0
NOVAVAX INC	COM NEW	670002401	45,328	250,000	SH		DFND	1	250,000	0	0
NUVATION BIO INC	COM CL A	67080N101	2,450	234,445	SH		DFND	1	234,445	0	0
NUVATION BIO INC	*W EXP 07/07/202	67080N119	222	83,332	SH		DFND	1	83,332	0	0
OLEMA PHARMACEUTICALS INC	COM	68062P106	105,084	3,195,544	SH		DFND	1	3,195,544	0	0
OMEROS CORP	COM	682143102	58,741	3,300,030	SH		DFND	1	3,300,030	0	0
OMEROS CORP	COM	682143102	17,800	1,000,000	SH	Call	DFND	1	1,000,000	0	0
ORCHARD THERAPEUTICS PLC	ADS	68570P101	1,863	256,649	SH		DFND	1	256,649	0	0
OUTLOOK THERAPEUTICS INC	*W EXP 02/18/202	69012T115	421	416,666	SH		DFND	1	416,666	0	0
PHARVARIS N V	COM	N69605108	23,811	864,143	SH		DFND	1	864,143	0	0
PLIANT THERAPEUTICS INC	COM	729139105	24,047	611,409	SH		DFND	1	611,409	0	0
PRAXIS PRECISION MEDICINES I	COM	74006W108	35,189	1,074,145	SH		DFND	1	1,074,145	0	0
PRECISION BIOSCIENCES INC	COM	74019P108	3,587	346,524	SH		DFND	1	346,524	0	0
PROMETHEUS BIOSCIENCES INC	COM	74349U108	36,623	2,098,024	SH		DFND	1	2,098,024	0	0
PROTARA THERAPEUTICS INC	COM STK	74365U107	5,509	350,000	SH		DFND	1	350,000	0	0
QUOTIENT LTD	SHS	G73268107	5,520	1,500,000	SH		DFND	1	1,500,000	0	0
REATA PHARMACEUTICALS INC	CL A	75615P103	39,880	400,000	SH		DFND	1	400,000	0	0
REPARE THERAPEUTICS INC	COM	760273102	14,185	462,205	SH		DFND	1	462,205	0	0
REPLIMUNE GROUP INC	COM	76029N106	3,814	125,000	SH		DFND	1	125,000	0	0
REVOLUTION MEDICINES INC	COM	76155X100	115,847	2,525,000	SH		DFND	1	2,525,000	0	0
ROCKET PHARMACEUTICALS INC	COM	77313F106	60,723	1,368,550	SH		DFND	1	1,368,550	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	5,217	70,000	SH		DFND	1	70,000	0	0
SILVERBACK THERAPEUTICS INC	COM	82835W108	21,815	500,000	SH		DFND	1	500,000	0	0
SORRENTO THERAPEUTICS INC	COM NEW	83587F202	22,742	2,750,000	SH		DFND	1	2,750,000	0	0
SPDR S&P 500 ETF TR	TR UNIT	78462F103	396,330	1,000,000	SH	Put	DFND	1	1,000,000	0	0
SPDR SER TR	S&P BIOTECH	78464A870	135,650	1,000,000	SH	Put	DFND	1	1,000,000	0	0
SPRINGWORKS THERAPEUTICS INC	COM	85205L107	9,196	125,000	SH		DFND	1	125,000	0	0
STOKE THERAPEUTICS INC	COM	86150R107	55,844	1,437,807	SH		DFND	1	1,437,807	0	0
TARSUS PHARMACEUTICALS INC	COM	87650L103	55,251	1,714,269	SH		DFND	1	1,714,269	0	0
TCR2 THERAPEUTICS INC	COM	87808K106	19,872	900,000	SH		DFND	1	900,000	0	0
THERAPEUTICS ACQUISITION COR	COM CL A	88339T103	5,255	500,000	SH		DFND	1	500,000	0	0
THERAVANCE BIOPHARMA INC	COM	G8807B106	11,226	550,000	SH		DFND	1	550,000	0	0
TRICIDA INC	COM	89610F101	2,264	427,975	SH		DFND	1	427,975	0	0
TURNING POINT THERAPEUTICS I	COM	90041T108	260,122	2,750,000	SH		DFND	1	2,750,000	0	0
TWIST BIOSCIENCE CORP	COM	90184D100	22,914	185,000	SH		DFND	1	185,000	0	0
UNIQURE NV	SHS	N90064101	8,422	250,000	SH		DFND	1	250,000	0	0
VERU INC	COM	92536C103	32,325	3,000,000	SH		DFND	1	3,000,000	0	0
VESPER HEALTHCARE ACQSTN COR	UNIT 99/99/9999	92538T203	4,620	400,000	SH		DFND	1	400,000	0	0
VIRIDIAN THERAPEUTICS INC	COM	92790C104	7,672	459,144	SH		DFND	1	459,144	0	0
X4 PHARMACEUTICALS INC	COM	98420X103	895	103,980	SH		DFND	1	103,980	0	0
Y-MABS THERAPEUTICS INC	COM	984241109	37,195	1,230,000	SH		DFND	1	1,230,000	0	0
ZAI LAB LTD	ADR	98887Q104	20,014	150,000	SH		DFND	1	150,000	0	0
ZYMEWORKS INC	COM	98985W102	63,160	2,000,000	SH		DFND	1	2,000,000	0	0