Pura Vida Investments 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
2SEVENTY BIO INC	COMMON STOCK	901384107	4,729	325,000	SH		SOLE		325,000	0	0
908 DEVICES INC	COM	65443P102	914	55,556	SH		SOLE		55,556	0	0
ABBVIE INC	COM	00287Y109	6,711	50,000	SH		SOLE		50,000	0	0
AMERISOURCEBERGEN CORP	PUT	03073E955	2,368	17,500	SH	Put	SOLE		17,500	0	0
AGILITI INC	COM	00848J104	704	49,200	SH		SOLE		49,200	0	0
AGILON HEALTH INC	COM	00857U107	3,513	150,000	SH		SOLE		150,000	0	0
AKOYA BIOSCIENCES INC	COM	00974H104	1,733	147,500	SH		SOLE		147,500	0	0
ALKERMES PLC	SHS	G01767105	1,117	50,000	SH		SOLE		50,000	0	0
AMYRIS INC	PUT	03236M950	2,044	700,000	SH	Put	SOLE		700,000	0	0
AMYLYX PHARMACEUTICALS INC	COM	03237H101	1,933	68,652	SH		SOLE		68,652	0	0
AMYRIS INC	COM NEW	03236M200	2,555	875,000	SH		SOLE		875,000	0	0
ANNEXON INC	COM	03589W102	2,315	374,630	SH		SOLE		374,630	0	0
APELLIS PHARMACEUTICALS INC	CALL	03753U906	13,660	200,000	SH	Call	SOLE		0	0	0
APOLLO ENDOSURGERY INC	COM	03767D108	2,353	427,057	SH		SOLE		427,057	0	0
APYX MEDICAL CORPORATION	COM	03837C106	6,771	1,508,062	SH		SOLE		1,508,062	0	0
ARDELYX INC	COM	039697107	60	50,000	SH		SOLE		50,000	0	0
ARDELYX INC	CALL	039697907	238	200,000	SH	Call	SOLE		0	0	0
ARK ETF TR	PUT	00214Q952	16,435	500,000	SH	Put	SOLE		500,000	0	0
ARK ETF TR	PUT	00214Q954	16,979	450,000	SH	Put	SOLE		450,000	0	0
ASTRAZENECA PLC	SPONSORED ADR	046353108	9,597	175,000	SH		SOLE		175,000	0	0
ATHIRA PHARMA INC	COM	04746L104	416	139,924	SH		SOLE		139,924	0	0
ATRICURE INC	COM	04963C209	5,976	152,834	SH		SOLE		152,834	0	0
AVADEL PHARMACEUTICALS PLC	SPONSORED ADR	05337M104	430	85,758	SH		SOLE		85,758	0	0
AVIDITY BIOSCIENCES INC	COM	05370A108	302	18,506	SH		SOLE		18,506	0	0
AVITA MEDICAL INC	COM	05380C102	4,527	858,951	SH		SOLE		858,951	0	0
ANAVEX LIFE SCIENCES CORP	CALL	032797900	2,064	200,000	SH	Call	SOLE		0	0	0
BAXTER INTL INC	CALL	071813909	10,810	200,700	SH	Call	SOLE		0	0	0
BECTON DICKINSON & CO	PUT	075887959	7,131	32,000	SH	Put	SOLE		32,000	0	0
BICYCLE THERAPEUTICS PLC	SPONSORED ADS	088786108	4,957	213,121	SH		SOLE		213,121	0	0
BIOGEN INC	CALL	09062X903	59,541	223,000	SH	Call	SOLE		0	0	0
BIOCRYST PHARMACEUTICALS INC	COM	09058V103	3,486	276,629	SH		SOLE		276,629	0	0
BIOGEN INC	COM	09062X103	1,335	5,000	SH		SOLE		5,000	0	0
BIOVENTUS INC	COM CL A	09075A108	4,107	586,696	SH		SOLE		586,696	0	0
BIOVIE INC	CL A NEW	09074F207	91	36,617	SH		SOLE		36,617	0	0
BLUEBIRD BIO INC	COM	09609G100	504	79,604	SH		SOLE		79,604	0	0
BOSTON SCIENTIFIC CORP	COM	101137107	1,884	48,635	SH		SOLE		48,635	0	0
BLUEPRINT MEDICINES CORP	PUT	09627Y959	659	10,000	SH	Put	SOLE		10,000	0	0
CEREVEL THERAPEUTICS HLDNG I	COM	15678U128	1,163	41,136	SH		SOLE		41,136	0	0
CELLDEX THERAPEUTICS INC NEW	CALL	15117B902	5,526	196,600	SH	Call	SOLE		0	0	0
COOPER COS INC	COM NEW	216648402	4,684	17,748	SH		SOLE		17,748	0	0
CUTERA INC	COM	232109108	46,449	1,018,619	SH		SOLE		1,018,619	0	0
CUTERA INC	CALL	232109908	4,560	100,000	SH	Call	SOLE		0	0	0
CYTEK BIOSCIENCES INC	COM	23285D109	7,760	527,164	SH		SOLE		527,164	0	0
CYTOKINETICS INC	COM NEW	23282W605	11,833	25,000	PRN		SOLE		25,000	0	0
CYTOKINETICS INC	COM NEW	23282W605	727	15,000	SH		SOLE		15,000	0	0
DEXCOM INC	COM	252131107	4,567	56,700	SH		SOLE		56,700	0	0
GINKGO BIOWORKS HOLDINGS INC	PUT	37611X950	1,872	600,000	SH	Put	SOLE		600,000	0	0
LILLY ELI & CO	COM	532457108	856	2,646	SH		SOLE		2,646	0	0
ELEVANCE HEALTH INC	PUT	036752953	15,898	35,000	SH	Put	SOLE		35,000	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	2,225	332,123	SH		SOLE		332,123	0	0
ESTABLISHMENT LABS HLDGS INC	CALL	G31249908	4,019	73,600	SH	Call	SOLE		0	0	0
ESTABLISHMENT LABS HLDGS INC	COM	G31249108	52,248	956,745	SH		SOLE		956,745	0	0
EXACT SCIENCES CORP	CALL	30063P905	12,184	375,000	SH	Call	SOLE		0	0	0
EXELIXIS INC	COM	30161Q104	1,176	75,000	SH		SOLE		75,000	0	0
FIRST TR EXCHANGE TRADED FD	PUT	33734X953	48,600	500,000	SH	Put	SOLE		500,000	0	0
GERON CORP	CALL	374163903	3,984	1,702,600	SH	Call	SOLE		0	0	0
GERON CORP	PUT	374163953	1,459	623,300	SH	Put	SOLE		623,300	0	0
GERON CORP	COM	374163103	1,170	500,000	SH		SOLE		500,000	0	0
GUARDANT HEALTH INC	CALL	40131M909	30,683	570,000	SH	Call	SOLE		0	0	0
GUARDANT HEALTH INC	PUT	40131M959	21,532	400,000	SH	Put	SOLE		400,000	0	0
GH RESEARCH PLC	ORDINARY SHARES	G3855L106	1,840	158,327	SH		SOLE		158,327	0	0
GLAUKOS CORP	CALL	377322902	32,476	610,000	SH	Call	SOLE		0	0	0
GLAUKOS CORP	COM	377322102	37,503	704,412	SH		SOLE		704,412	0	0
GOSSAMER BIO INC	PUT	38341P952	2,035	169,900	SH	Put	SOLE		169,900	0	0
GOSSAMER BIO INC	NOTE 5.000% 6/0	38341PAA0	516	5,000	PRN		SOLE		5,000	0	0
GOSSAMER BIO INC	COM	38341P102	4,096	341,878	SH		SOLE		341,878	0	0
GREENWICH LIFESCIENCES INC	COM	396879108	179	19,667	SH		SOLE		19,667	0	0
GUARDANT HEALTH INC	COM	40131M109	21,585	400,984	SH		SOLE		400,984	0	0
HOLOGIC INC	PUT	436440951	7,097	110,000	SH	Put	SOLE		110,000	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	798	12,900	SH		SOLE		12,900	0	0
ICAD INC	COM NEW	44934S206	1,849	880,558	SH		SOLE		880,558	0	0
INTERCEPT PHARMACEUTICALS IN	CALL	45845P908	2,790	200,000	SH	Call	SOLE		0	0	0
ICU MED INC	COM	44930G107	9,413	62,500	SH		SOLE		62,500	0	0
ICU MED INC	CALL	44930G907	18,825	125,000	SH	Call	SOLE		0	0	0
IDEXX LABS INC	PUT	45168D954	12,380	38,000	SH	Put	SOLE		38,000	0	0
ISHARES TR	PUT	464288950	47,180	1,000,000	SH	Put	SOLE		1,000,000	0	0
ILLUMINA INC	COM	452327109	10,493	55,000	SH		SOLE		55,000	0	0
ILLUMINA INC	CALL	452327909	16,217	85,000	SH	Call	SOLE		0	0	0
INMODE LTD	PUT	M5425M953	2,329	80,000	SH	Put	SOLE		80,000	0	0
INSPIRE MED SYS INC	COM	457730109	35,755	201,584	SH		SOLE		201,584	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	3,699	19,732	SH		SOLE		19,732	0	0
IOVANCE BIOTHERAPEUTICS INC	COM	462260100	1,385	144,528	SH		SOLE		144,528	0	0
IRHYTHM TECHNOLOGIES INC	COM	450056106	5,953	47,521	SH		SOLE		47,521	0	0
IRHYTHM TECHNOLOGIES INC	PUT	450056956	5,888	47,000	SH	Put	SOLE		47,000	0	0
IVERIC BIO INC	CALL	46583P902	11,295	629,600	SH	Call	SOLE		0	0	0
IVERIC BIO INC	PUT	46583P952	610	34,000	SH	Put	SOLE		34,000	0	0
INTUITIVE SURGICAL INC	CALL	46120E902	17,807	95,000	SH	Call	SOLE		0	0	0
IVERIC BIO INC	COM	46583P102	17,499	975,430	SH		SOLE		975,430	0	0
ISHARES TR	PUT	464287955	98,952	600,000	SH	Put	SOLE		600,000	0	0
JOUNCE THERAPEUTICS INC	CALL	481116901	426	182,200	SH	Call	SOLE		0	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	12,083	832,702	SH		SOLE		832,702	0	0
KODIAK SCIENCES INC	CALL	50015M909	1,548	200,000	SH	Call	SOLE		0	0	0
LANTHEUS HLDGS INC	COM	516544103	8,704	123,765	SH		SOLE		123,765	0	0
LIQUIDIA CORPORATION	COM NEW	53635D202	2,926	537,870	SH		SOLE		537,870	0	0
LIVANOVA PLC	SHS	G5509L101	12,342	243,089	SH		SOLE		243,089	0	0
LIVANOVA PLC	CALL	G5509L901	34,529	680,100	SH	Call	SOLE		0	0	0
LYRA THERAPEUTICS INC	COM	55234L105	12,577	2,510,302	SH		SOLE		2,510,302	0	0
MACROGENICS INC	COM	556099109	182	52,573	SH		SOLE		52,573	0	0
MASIMO CORP	CALL	574795900	4,235	30,000	SH	Call	SOLE		0	0	0
MASIMO CORP	COM	574795100	3,642	25,800	SH		SOLE		25,800	0	0
MEDPACE HLDGS INC	PUT	58506Q959	11,788	75,000	SH	Put	SOLE		75,000	0	0
MERUS N V	COM	N5749R100	2,717	135,632	SH		SOLE		135,632	0	0
MILESTONE PHARMACEUTICALS IN	COM	59935V107	5,482	596,531	SH		SOLE		596,531	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	1,397	20,000	SH		SOLE		20,000	0	0
ADVISORSHARES TR	CALL	00768Y903	20,089	2,254,700	SH	Call	SOLE		0	0	0
METTLER TOLEDO INTERNATIONAL	PUT	592688955	21,682	20,000	SH	Put	SOLE		20,000	0	0
NANOSTRING TECHNOLOGIES INC	COM	63009R109	9,752	763,700	SH		SOLE		763,700	0	0
INARI MED INC	PUT	45332Y959	3,196	44,000	SH	Put	SOLE		44,000	0	0
NGM BIOPHARMACEUTICALS INC	CALL	62921N905	789	60,300	SH	Call	SOLE		0	0	0
NGM BIOPHARMACEUTICALS INC	PUT	62921N955	785	60,000	SH	Put	SOLE		60,000	0	0
NGM BIOPHARMACEUTICALS INC	COM	62921N105	1,775	135,696	SH		SOLE		135,696	0	0
NEKTAR THERAPEUTICS	CALL	640268908	117	36,600	SH	Call	SOLE		0	0	0
NANOSTRING TECHNOLOGIES INC	CALL	63009R909	17,750	1,390,000	SH	Call	SOLE		0	0	0
INTELLIA THERAPEUTICS INC	PUT	45826J955	5,613	100,300	SH	Put	SOLE		100,300	0	0
NATERA INC	CALL	632307904	4,382	100,000	SH	Call	SOLE		0	0	0
NOVOCURE LTD	PUT	G6674U958	11,025	145,100	SH	Put	SOLE		145,100	0	0
NYXOAH S A	SHS	B6S7WD106	1,423	221,949	SH		SOLE		221,949	0	0
OLINK HLDG AB	SPONSORED ADS	680710100	7,523	619,723	SH		SOLE		619,723	0	0
ONCOCYTE CORP	COM	68235C107	13,181	18,056,274	SH		SOLE		18,056,274	0	0
ORAMED PHARMACEUTICALS INC	CALL	68403P903	1,202	185,500	SH	Call	SOLE		0	0	0
OAK STR HEALTH INC	PUT	67181A957	2,452	100,000	SH	Put	SOLE		100,000	0	0
OUTSET MED INC	COM	690145107	14,411	904,619	SH		SOLE		904,619	0	0
PACIFIC BIOSCIENCES CALIF IN	PUT	69404D958	9,860	1,700,000	SH	Put	SOLE		1,700,000	0	0
PFIZER INC	CALL	717081903	4,376	100,000	SH	Call	SOLE		0	0	0
PFIZER INC	COM	717081103	2,188	50,000	SH		SOLE		50,000	0	0
KONINKLIJKE PHILIPS N V	PUT	500472953	6,156	400,000	SH	Put	SOLE		400,000	0	0
VANECK ETF TRUST	PUT	92189F952	26,896	400,000	SH	Put	SOLE		400,000	0	0
PRIVIA HEALTH GROUP INC	COM	74276R102	4,598	135,000	SH		SOLE		135,000	0	0
PROMETHEUS BIOSCIENCES INC	COM	74349U108	1,722	29,188	SH		SOLE		29,188	0	0
PRIVIA HEALTH GROUP INC	CALL	74276R902	6,812	200,000	SH	Call	SOLE		0	0	0
PROVENTION BIO INC	CALL	74374N902	252	56,100	SH	Call	SOLE		0	0	0
PULMONX CORP	COM	745848101	12,978	778,978	SH		SOLE		778,978	0	0
QIAGEN NV	SHS NEW	N72482123	454	11,000	SH		SOLE		11,000	0	0
INVESCO QQQ TR	PUT	46090E953	33,408	125,000	SH	Put	SOLE		125,000	0	0
QUANTERIX CORP	CALL	74766Q901	5,510	500,000	SH	Call	SOLE		0	0	0
QUANTERIX CORP	COM	74766Q101	156	14,200	SH		SOLE		14,200	0	0
QUOTIENT LTD	SHS	G73268107	919	6,126,468	SH		SOLE		6,126,468	0	0
R1 RCM INC	COM	77634L105	4,825	260,400	SH		SOLE		260,400	0	0
AVITA MEDICAL INC	CALL	05380C902	2,372	450,000	SH	Call	SOLE		0	0	0
REATA PHARMACEUTICALS INC	CL A	75615P103	1,397	55,596	SH		SOLE		55,596	0	0
RENOVACOR INC	*W EXP 99/99/999	75989E114	12	150,632	SH		SOLE		150,632	0	0
RENOVACOR INC	COM	75989E106	150	59,352	SH		SOLE		59,352	0	0
RESMED INC	COM	761152107	3,275	15,000	SH		SOLE		15,000	0	0
REVOLUTION MEDICINES INC	COM	76155X100	1,873	95,000	SH		SOLE		95,000	0	0
REPLIGEN CORP	PUT	759916959	5,613	30,000	SH	Put	SOLE		30,000	0	0
ROCKET PHARMACEUTICALS INC	COM	77313F106	798	50,000	SH		SOLE		50,000	0	0
ROIVANT SCIENCES LTD	*W EXP 09/30/202	G76279119	78	199,648	SH		SOLE		199,648	0	0
PROMETHEUS BIOSCIENCES INC	PUT	74349U958	738	12,500	SH	Put	SOLE		12,500	0	0
BOSTON BEER INC	PUT	100557957	12,946	40,000	SH	Put	SOLE		40,000	0	0
SANOFI	SPONSORED ADR	80105N105	3,714	97,684	SH		SOLE		97,684	0	0
SAREPTA THERAPEUTICS INC	DEBT 1.250% 9/1	803607AC4	2,586	25,000	PRN		SOLE		25,000	0	0
SAVARA INC	COM	805111101	147	95,014	SH		SOLE		95,014	0	0
SCHRODINGER INC	COM	80810D103	6,495	260,000	SH		SOLE		260,000	0	0
SCIENCE 37 HOLDINGS INC	COM	808644108	1,781	1,106,400	SH		SOLE		1,106,400	0	0
SOMALOGIC INC	*W EXP 08/31/202	83444K113	90	204,401	SH		SOLE		204,401	0	0
SOMALOGIC INC	CLASS A COM	83444K105	6,418	2,213,200	SH		SOLE		2,213,200	0	0
SONENDO INC	COM	835431107	1,095	1,023,424	SH		SOLE		1,023,424	0	0
SOPHIA GENETICS SA	ORDINARY SHARES	H82027105	2,357	896,240	SH		SOLE		896,240	0	0
SPRINGBIG HOLDINGS INC	*W EXP 06/14/202	85021Q116	1	10,000	SH		SOLE		10,000	0	0
SPDR S&P 500 ETF TR	PUT	78462F953	44,648	125,000	SH	Put	SOLE		125,000	0	0
SAREPTA THERAPEUTICS INC	CALL	803607900	22,108	200,000	SH	Call	SOLE		0	0	0
STAAR SURGICAL CO	PUT	852312955	26,104	370,000	SH	Put	SOLE		370,000	0	0
STAAR SURGICAL CO	COM PAR $0.01	852312305	12,227	173,310	SH		SOLE		173,310	0	0
STANDARD BIOTOOLS INC	COM	34385P108	278	253,132	SH		SOLE		253,132	0	0
STERIS PLC	PUT	G8473T950	4,988	30,000	SH	Put	SOLE		30,000	0	0
STRYKER CORPORATION	PUT	863667951	9,114	45,000	SH	Put	SOLE		45,000	0	0
TALKSPACE INC	*W EXP 06/21/202	87427V111	113	427,194	SH		SOLE		427,194	0	0
TANDEM DIABETES CARE INC	COM NEW	875372203	3,589	75,000	SH		SOLE		75,000	0	0
TRICIDA INC	CALL	89610F901	3,334	318,100	SH	Call	SOLE		0	0	0
TELADOC HEALTH INC	PUT	87918A955	7,605	300,000	SH	Put	SOLE		300,000	0	0
TELA BIO INC	COM	872381108	4,431	520,079	SH		SOLE		520,079	0	0
TENET HEALTHCARE CORP	COM NEW	88033G407	5,158	100,000	SH		SOLE		100,000	0	0
TERNS PHARMACEUTICALS INC	COM	880881107	4,291	728,600	SH		SOLE		728,600	0	0
TELEFLEX INCORPORATED	PUT	879369956	7,051	35,000	SH	Put	SOLE		35,000	0	0
TG THERAPEUTICS INC	COM	88322Q108	7,109	1,200,813	SH		SOLE		1,200,813	0	0
TG THERAPEUTICS INC	PUT	88322Q958	2,919	493,100	SH	Put	SOLE		493,100	0	0
TANDEM DIABETES CARE INC	CALL	875372903	4,785	100,000	SH	Call	SOLE		0	0	0
TRANSMEDICS GROUP INC	COM	89377M109	5,009	120,000	SH		SOLE		120,000	0	0
TRAVERE THERAPEUTICS INC	NOTE 2.250% 3/0	89422GAA5	511	5,000	PRN		SOLE		5,000	0	0
TRUPANION INC	PUT	898202956	4,457	75,000	SH	Put	SOLE		75,000	0	0
10X GENOMICS INC	PUT	88025U959	2,848	100,000	SH	Put	SOLE		100,000	0	0
UNITEDHEALTH GROUP INC	PUT	91324P952	30,302	60,000	SH	Put	SOLE		60,000	0	0
UNITED THERAPEUTICS CORP DEL	COM	91307C102	26,182	125,046	SH		SOLE		125,046	0	0
VERASTEM INC	COM	92337C104	854	1,004,272	SH		SOLE		1,004,272	0	0
VERONA PHARMA PLC	SPONSORED ADS	925050106	1,022	100,000	SH		SOLE		100,000	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	7,749	26,763	SH		SOLE		26,763	0	0
VERU INC	CALL	92536C903	2,304	200,000	SH	Call	SOLE		0	0	0
VIEWRAY INC	COM	92672L107	49,740	13,664,939	SH		SOLE		13,664,939	0	0
VIRIDIAN THERAPEUTICS INC	COM	92790C104	1,538	75,003	SH		SOLE		75,003	0	0
VIEWRAY INC	CALL	92672L907	9,100	2,500,000	SH	Call	SOLE		0	0	0
WALGREENS BOOTS ALLIANCE INC	PUT	931427958	7,850	250,000	SH	Put	SOLE		250,000	0	0
WM TECHNOLOGY INC	*W EXP 06/16/202	92971A117	17	50,000	SH		SOLE		50,000	0	0
SPDR SER TR	CALL	78464A900	7,869	99,200	SH	Call	SOLE		0	0	0
SPDR SER TR	PUT	78464A950	47,592	600,000	SH	Put	SOLE		600,000	0	0
ATAI LIFE SCIENCES NV	SHS	N0731H103	2,389	721,824	SH		SOLE		721,824	0	0
MEDAVAIL HOLDINGS INC	COM	58406B103	554	714,120	SH		SOLE		714,120	0	0
ZIMMER BIOMET HOLDINGS INC	CALL	98956P902	5,228	50,000	SH	Call	SOLE		0	0	0