Pura Vida Investments 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
2SEVENTY BIO INC	COMMON STOCK	901384107	2,354,765	251,309	SH		SOLE		251,309	0	0
89BIO INC	COM	282559103	636,500	50,000	SH		SOLE		50,000	0	0
AGILENT TECHNOLOGIES INC	PUT	00846U951	4,489,500	30,000	SH	Put	SOLE		30,000	0	0
ADMA BIOLOGICS INC	COM	000899104	1,164,000	300,000	SH		SOLE		300,000	0	0
ADAPTIVE BIOTECHNOLOGIES COR	CALL	00650F909	5,730,000	750,000	SH	Call	SOLE		0	0	0
AEGLEA BIOTHERAPEUTICS INC	COM	00773J103	471,809	1,048,697	SH		SOLE		1,048,697	0	0
ALIGN TECHNOLOGY INC	CALL	016255901	2,636,250	12,500	SH	Call	SOLE		0	0	0
ALKERMES PLC	SHS	G01767105	1,306,500	50,000	SH		SOLE		50,000	0	0
ALNYLAM PHARMACEUTICALS INC	CALL	02043Q907	15,542,310	65,400	SH	Call	SOLE		0	0	0
ALNYLAM PHARMACEUTICALS INC	PUT	02043Q957	7,129,500	30,000	SH	Put	SOLE		30,000	0	0
ALPINE IMMUNE SCIENCES INC	COM	02083G100	227,291	30,924	SH		SOLE		30,924	0	0
ANNEXON INC	COM	03589W102	1,565,135	302,734	SH		SOLE		302,734	0	0
APELLIS PHARMACEUTICALS INC	CALL	03753U906	10,342,000	200,000	SH	Call	SOLE		0	0	0
APPLIED THERAPEUTICS INC	COM	03828A101	77,257	101,654	SH		SOLE		101,654	0	0
APYX MEDICAL CORPORATION	CALL	03837C906	1,965,600	840,000	SH	Call	SOLE		0	0	0
APYX MEDICAL CORPORATION	COM	03837C106	1,421,690	607,560	SH		SOLE		607,560	0	0
ARCTURUS THERAPEUTICS HLDGS	COM	03969T109	848,000	50,000	SH		SOLE		50,000	0	0
ARK ETF TR	PUT	00214Q952	25,407,000	900,000	SH	Put	SOLE		900,000	0	0
ARK ETF TR	PUT	00214Q954	38,269,000	1,225,000	SH	Put	SOLE		1,225,000	0	0
ARROWHEAD PHARMACEUTICALS IN	CALL	04280A900	803,088	19,800	SH	Call	SOLE		0	0	0
ATHIRA PHARMA INC	COM	04746L104	246,309	77,700	SH		SOLE		77,700	0	0
AVADEL PHARMACEUTICALS PLC	SPONSORED ADR	05337M104	1,861,600	260,000	SH		SOLE		260,000	0	0
AVANTOR INC	COM	05352A100	731,823	34,700	SH		SOLE		34,700	0	0
AVITA MEDICAL INC	COM	05380C102	6,165,938	934,233	SH		SOLE		934,233	0	0
ANAVEX LIFE SCIENCES CORP	CALL	032797900	2,778,000	300,000	SH	Call	SOLE		0	0	0
AZENTA INC	COM	114340102	7,335,720	126,000	SH		SOLE		126,000	0	0
BAXTER INTL INC	CALL	071813909	45,873,000	900,000	SH	Call	SOLE		0	0	0
BICYCLE THERAPEUTICS PLC	SPONSORED ADS	088786108	7,074,844	239,015	SH		SOLE		239,015	0	0
BIOGEN INC	CALL	09062X903	28,633,528	103,400	SH	Call	SOLE		0	0	0
BIOCRYST PHARMACEUTICALS INC	COM	09058V103	1,224,101	106,629	SH		SOLE		106,629	0	0
BIOGEN INC	COM	09062X103	17,368,422	62,720	SH		SOLE		62,720	0	0
BIONTECH SE	SPONSORED ADS	09075V102	4,235,453	28,195	SH		SOLE		28,195	0	0
BIO-TECHNE CORP	COM	09073M104	5,635,840	68,000	SH		SOLE		68,000	0	0
BIOVENTUS INC	COM CL A	09075A108	65,250	25,000	SH		SOLE		25,000	0	0
CEREVEL THERAPEUTICS HLDNG I	COM	15678U128	441,560	14,000	SH		SOLE		14,000	0	0
CANOPY GROWTH CORP	CALL	138035900	4,042,500	1,750,000	SH	Call	SOLE		0	0	0
CHINOOK THERAPEUTICS INC	COM	16961L106	2,358,000	90,000	SH		SOLE		90,000	0	0
CELLDEX THERAPEUTICS INC NEW	CALL	15117B902	8,762,462	196,600	SH	Call	SOLE		0	0	0
CONCERT PHARMACEUTICALS INC	CALL	206022905	347,480	59,500	SH	Call	SOLE		0	0	0
CONMED CORP	PUT	207410951	4,910,656	55,400	SH	Put	SOLE		55,400	0	0
CONCERT PHARMACEUTICALS INC	COM	206022105	1,206,106	206,525	SH		SOLE		206,525	0	0
COOPER COS INC	COM NEW	216648402	5,092,318	15,400	SH		SOLE		15,400	0	0
CUREVAC N V	COM	N2451R105	731,939	121,383	SH		SOLE		121,383	0	0
CUREVAC N V	COM	N2451R105	41,724	6,862	SH		SOLE		6,862	0	0
CUTERA INC	COM	232109108	45,812,849	1,036,021	SH		SOLE		1,036,021	0	0
CUTERA INC	CALL	232109908	10,723,350	242,500	SH	Call	SOLE		0	0	0
CUREVAC N V	CALL	N2451R905	603,000	100,000	SH	Call	SOLE		0	0	0
CVS HEALTH CORP	PUT	126650950	9,319,000	100,000	SH	Put	SOLE		100,000	0	0
CYTEK BIOSCIENCES INC	COM	23285D109	4,295,847	420,749	SH		SOLE		420,749	0	0
CYTOKINETICS INC	COM NEW	23282W605	11,229,835	25,000	PRN		SOLE		25,000	0	0
DEXCOM INC	COM	252131107	8,055,780	71,139	SH		SOLE		71,139	0	0
DANAHER CORPORATION	PUT	235851952	17,252,300	65,000	SH	Put	SOLE		65,000	0	0
ELEVANCE HEALTH INC	PUT	036752953	10,259,400	20,000	SH	Put	SOLE		20,000	0	0
ESPERION THERAPEUTICS INC NE	COM	29664W105	1,920,790	308,313	SH		SOLE		308,313	0	0
ESTABLISHMENT LABS HLDGS INC	CALL	G31249908	1,641,250	25,000	SH	Call	SOLE		0	0	0
ESTABLISHMENT LABS HLDGS INC	COM	G31249108	62,549,154	952,767	SH		SOLE		952,767	0	0
89BIO INC	CALL	282559903	649,230	51,000	SH	Call	SOLE		0	0	0
EVAXION BIOTECH A S	ADS	29970R105	29,895	16,842	SH		SOLE		16,842	0	0
EVOLENT HEALTH INC	CL A	30050B101	3,262,896	116,200	SH		SOLE		116,200	0	0
EVOLUS INC	COM	30052C107	375,500	50,000	SH		SOLE		50,000	0	0
EXACT SCIENCES CORP	CALL	30063P905	13,615,250	275,000	SH	Call	SOLE		0	0	0
EXELIXIS INC	COM	30161Q104	1,203,000	75,000	SH		SOLE		75,000	0	0
FIRST TR EXCHANGE TRADED FD	PUT	33734X953	76,111,000	700,000	SH	Put	SOLE		700,000	0	0
GERON CORP	CALL	374163903	4,391,332	1,814,600	SH	Call	SOLE		0	0	0
GERON CORP	PUT	374163953	1,508,386	623,300	SH	Put	SOLE		623,300	0	0
GUARDANT HEALTH INC	CALL	40131M909	11,122,080	408,900	SH	Call	SOLE		0	0	0
GH RESEARCH PLC	ORDINARY SHARES	G3855L106	1,538,938	158,327	SH		SOLE		158,327	0	0
GLAUKOS CORP	CALL	377322902	10,920,000	250,000	SH	Call	SOLE		0	0	0
GLAUKOS CORP	COM	377322102	33,242,620	761,049	SH		SOLE		761,049	0	0
GLYCOMIMETICS INC	CALL	38000Q902	535,098	176,600	SH	Call	SOLE		0	0	0
GLYCOMIMETICS INC	COM	38000Q102	95,793	31,615	SH		SOLE		31,615	0	0
GOSSAMER BIO INC	NOTE 5.000% 6/0	38341PAA0	161,750	5,000	PRN		SOLE		5,000	0	0
GUARDANT HEALTH INC	COM	40131M109	11,610,973	426,874	SH		SOLE		426,874	0	0
HOLOGIC INC	PUT	436440951	7,884,974	105,400	SH	Put	SOLE		105,400	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	1,468,020	12,900	SH		SOLE		12,900	0	0
HENRY SCHEIN INC	PUT	806407952	11,181,800	140,000	SH	Put	SOLE		140,000	0	0
HUMANA INC	PUT	444859952	10,243,800	20,000	SH	Put	SOLE		20,000	0	0
INTEGRA LIFESCIENCES HLDGS C	PUT	457985958	11,298,105	201,500	SH	Put	SOLE		201,500	0	0
ICAD INC	COM NEW	44934S206	2,028,864	1,108,669	SH		SOLE		1,108,669	0	0
ICU MED INC	COM	44930G107	6,273,216	39,835	SH		SOLE		39,835	0	0
ICU MED INC	CALL	44930G907	18,897,600	120,000	SH	Call	SOLE		0	0	0
IDEXX LABS INC	PUT	45168D954	8,159,200	20,000	SH	Put	SOLE		20,000	0	0
ISHARES TR	PUT	464288950	78,855,000	1,500,000	SH	Put	SOLE		1,500,000	0	0
ILLUMINA INC	CALL	452327909	11,626,500	57,500	SH	Call	SOLE		0	0	0
IMMUNOGEN INC	COM	45253H101	248,000	50,000	SH		SOLE		50,000	0	0
INCYTE CORP	COM	45337C102	2,441,728	30,400	SH		SOLE		30,400	0	0
INHIBRX INC	COM	45720L107	2,305,688	93,575	SH		SOLE		93,575	0	0
INMODE LTD	PUT	M5425M953	7,140,000	200,000	SH	Put	SOLE		200,000	0	0
INSPIRE MED SYS INC	COM	457730109	50,623,850	200,984	SH		SOLE		200,984	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	2,653,500	10,000	SH		SOLE		10,000	0	0
IRHYTHM TECHNOLOGIES INC	CALL	450056906	6,556,900	70,000	SH	Call	SOLE		0	0	0
IVERIC BIO INC	CALL	46583P902	4,915,736	229,600	SH	Call	SOLE		0	0	0
IVERIC BIO INC	PUT	46583P952	421,777	19,700	SH	Put	SOLE		19,700	0	0
INTUITIVE SURGICAL INC	CALL	46120E902	29,188,500	110,000	SH	Call	SOLE		0	0	0
IVERIC BIO INC	COM	46583P102	25,327,495	1,182,975	SH		SOLE		1,182,975	0	0
ISHARES TR	PUT	464287955	95,898,000	550,000	SH	Put	SOLE		550,000	0	0
KALVISTA PHARMACEUTICALS INC	COM	483497103	4,953,066	732,702	SH		SOLE		732,702	0	0
LANTHEUS HLDGS INC	COM	516544103	5,945,248	116,665	SH		SOLE		116,665	0	0
LIQUIDIA CORPORATION	COM NEW	53635D202	1,328,368	208,535	SH		SOLE		208,535	0	0
LIVANOVA PLC	SHS	G5509L101	12,660,399	227,951	SH		SOLE		227,951	0	0
LIVANOVA PLC	CALL	G5509L901	16,717,540	301,000	SH	Call	SOLE		0	0	0
PULMONX CORP	CALL	745848901	843,000	100,000	SH	Call	SOLE		0	0	0
MERRIMACK PHARMACEUTICALS IN	CALL	590328909	460,692	40,200	SH	Call	SOLE		0	0	0
MADRIGAL PHARMACEUTICALS INC	PUT	558868955	10,449,000	36,000	SH	Put	SOLE		36,000	0	0
MEDTRONIC PLC	PUT	G5960L953	10,103,600	130,000	SH	Put	SOLE		130,000	0	0
MERRIMACK PHARMACEUTICALS IN	COM NEW	590328209	734,586	64,100	SH		SOLE		64,100	0	0
MILESTONE PHARMACEUTICALS IN	COM	59935V107	1,472,280	371,788	SH		SOLE		371,788	0	0
MIRATI THERAPEUTICS INC	CALL	60468T905	5,536,882	122,200	SH	Call	SOLE		0	0	0
MIRATI THERAPEUTICS INC	PUT	60468T955	566,375	12,500	SH	Put	SOLE		12,500	0	0
ADVISORSHARES TR	CALL	00768Y903	15,727,500	2,250,000	SH	Call	SOLE		0	0	0
NANOSTRING TECHNOLOGIES INC	COM	63009R109	7,249,512	909,600	SH		SOLE		909,600	0	0
INARI MED INC	PUT	45332Y959	1,906,800	30,000	SH	Put	SOLE		30,000	0	0
NATERA INC	COM	632307104	6,628,050	165,000	SH		SOLE		165,000	0	0
NGM BIOPHARMACEUTICALS INC	CALL	62921N905	302,706	60,300	SH	Call	SOLE		0	0	0
NGM BIOPHARMACEUTICALS INC	COM	62921N105	417,433	83,154	SH		SOLE		83,154	0	0
NOVOCURE LTD	ORD SHS	G6674U108	3,667,500	50,000	SH		SOLE		50,000	0	0
NANOSTRING TECHNOLOGIES INC	CALL	63009R909	10,251,811	1,286,300	SH	Call	SOLE		0	0	0
NUVALENT INC	COM	670703107	2,100,175	70,523	SH		SOLE		70,523	0	0
NOVOCURE LTD	CALL	G6674U908	2,567,250	35,000	SH	Call	SOLE		0	0	0
NOVOCURE LTD	PUT	G6674U958	19,445,085	265,100	SH	Put	SOLE		265,100	0	0
INVITAE CORP	CALL	46185L903	744,000	400,000	SH	Call	SOLE		0	0	0
NYXOAH S A	SHS	B6S7WD106	801,378	149,131	SH		SOLE		149,131	0	0
OLINK HLDG AB	SPONSORED ADS	680710100	12,439,423	490,127	SH		SOLE		490,127	0	0
OUTSET MED INC	CALL	690145907	9,703,156	375,800	SH	Call	SOLE		0	0	0
ONCOCYTE CORP	COM	68235C107	5,794,258	18,056,274	SH		SOLE		18,056,274	0	0
ORAMED PHARMACEUTICALS INC	CALL	68403P903	2,231,565	185,500	SH	Call	SOLE		0	0	0
OUTSET MED INC	COM	690145107	11,732,350	454,390	SH		SOLE		454,390	0	0
PACIFIC BIOSCIENCES CALIF IN	COM	69404D108	818,000	100,000	SH		SOLE		100,000	0	0
PENUMBRA INC	CALL	70975L907	9,321,074	41,900	SH	Call	SOLE		0	0	0
PFIZER INC	CALL	717081903	5,124,000	100,000	SH	Call	SOLE		0	0	0
KONINKLIJKE PHILIPS N V	PUT	500472953	4,497,000	300,000	SH	Put	SOLE		300,000	0	0
VANECK ETF TRUST	PUT	92189F952	31,096,000	400,000	SH	Put	SOLE		400,000	0	0
PROMETHEUS BIOSCIENCES INC	COM	74349U108	2,310,000	21,000	SH		SOLE		21,000	0	0
PROTHENA CORP PLC	SHS	G72800108	3,856,000	64,000	SH		SOLE		64,000	0	0
PRIVIA HEALTH GROUP INC	CALL	74276R902	7,948,500	350,000	SH	Call	SOLE		0	0	0
PULMONX CORP	COM	745848101	8,567,055	1,016,258	SH		SOLE		1,016,258	0	0
QIAGEN NV	SHS NEW	N72482123	548,570	11,000	SH		SOLE		11,000	0	0
INVESCO QQQ TR	PUT	46090E953	107,843,400	405,000	SH	Put	SOLE		405,000	0	0
QUANTERIX CORP	CALL	74766Q901	15,315,330	1,105,800	SH	Call	SOLE		0	0	0
QUANTERIX CORP	COM	74766Q101	7,287,053	526,141	SH		SOLE		526,141	0	0
R1 RCM INC	COM	77634L105	4,927,500	450,000	SH		SOLE		450,000	0	0
ROCKET PHARMACEUTICALS INC	PUT	77313F956	2,935,500	150,000	SH	Put	SOLE		150,000	0	0
RELMADA THERAPEUTICS INC	COM	75955J402	77,593	22,233	SH		SOLE		22,233	0	0
REPLIGEN CORP	PUT	759916959	3,352,338	19,800	SH	Put	SOLE		19,800	0	0
RELMADA THERAPEUTICS INC	CALL	75955J902	69,800	20,000	SH	Call	SOLE		0	0	0
ROIVANT SCIENCES LTD	*W EXP 09/30/202	G76279119	387,317	199,648	SH		SOLE		199,648	0	0
PROMETHEUS BIOSCIENCES INC	PUT	74349U958	1,375,000	12,500	SH	Put	SOLE		12,500	0	0
SAREPTA THERAPEUTICS INC	DEBT 1.250% 9/1	803607AC4	2,893,750	25,000	PRN		SOLE		25,000	0	0
SAVARA INC	COM	805111101	147,272	95,014	SH		SOLE		95,014	0	0
SCHRODINGER INC	COM	80810D103	4,859,400	260,000	SH		SOLE		260,000	0	0
SEER INC	PUT	81578P956	1,450,000	250,000	SH	Put	SOLE		250,000	0	0
THE BEAUTY HEALTH COMPANY	PUT	88331L958	1,820,000	200,000	SH	Put	SOLE		200,000	0	0
SUMMIT THERAPEUTICS INC	CALL	86627T908	850,000	200,000	SH	Call	SOLE		0	0	0
SOMALOGIC INC	*W EXP 08/31/202	83444K113	81,760	204,401	SH		SOLE		204,401	0	0
SONENDO INC	COM	835431107	13,912,407	4,916,045	SH		SOLE		4,916,045	0	0
SOPHIA GENETICS SA	ORDINARY SHARES	H82027105	1,553,314	754,036	SH		SOLE		754,036	0	0
SPRINGBIG HOLDINGS INC	*W EXP 06/14/202	85021Q116	211	10,000	SH		SOLE		10,000	0	0
SPDR S&P 500 ETF TR	PUT	78462F953	110,904,700	290,000	SH	Put	SOLE		290,000	0	0
SAREPTA THERAPEUTICS INC	CALL	803607900	25,916,000	200,000	SH	Call	SOLE		0	0	0
STAAR SURGICAL CO	PUT	852312955	20,629,500	425,000	SH	Put	SOLE		425,000	0	0
STAAR SURGICAL CO	COM PAR $0.01	852312305	8,412,467	173,310	SH		SOLE		173,310	0	0
STERIS PLC	SHS USD	G8473T100	2,862,695	15,500	SH		SOLE		15,500	0	0
STEVANATO GROUP S P A	ORD SHS	T9224W109	754,740	42,000	SH		SOLE		42,000	0	0
SUTRO BIOPHARMA INC	COM	869367102	253,785	31,409	SH		SOLE		31,409	0	0
STRYKER CORPORATION	PUT	863667951	22,004,100	90,000	SH	Put	SOLE		90,000	0	0
SYNEOS HEALTH INC	CALL	87166B902	5,502,000	150,000	SH	Call	SOLE		0	0	0
TALKSPACE INC	*W EXP 06/21/202	87427V111	31,142	427,194	SH		SOLE		427,194	0	0
TRICIDA INC	CALL	89610F901	45,870	300,000	SH	Call	SOLE		0	0	0
TELA BIO INC	COM	872381108	5,980,909	520,079	SH		SOLE		520,079	0	0
TERNS PHARMACEUTICALS INC	COM	880881107	6,159,704	605,079	SH		SOLE		605,079	0	0
TG THERAPEUTICS INC	COM	88322Q108	5,972,127	504,829	SH		SOLE		504,829	0	0
TG THERAPEUTICS INC	CALL	88322Q908	2,957,500	250,000	SH	Call	SOLE		0	0	0
TG THERAPEUTICS INC	PUT	88322Q958	7,016,373	593,100	SH	Put	SOLE		593,100	0	0
TRANSMEDICS GROUP INC	PUT	89377M959	5,554,800	90,000	SH	Put	SOLE		90,000	0	0
THERMO FISHER SCIENTIFIC INC	PUT	883556952	22,027,600	40,000	SH	Put	SOLE		40,000	0	0
TRANSMEDICS GROUP INC	COM	89377M109	5,554,800	90,000	SH		SOLE		90,000	0	0
TRAVERE THERAPEUTICS INC	NOTE 2.250% 3/0	89422GAA5	457,500	5,000	PRN		SOLE		5,000	0	0
TRUPANION INC	PUT	898202956	3,564,750	75,000	SH	Put	SOLE		75,000	0	0
TWIST BIOSCIENCE CORP	PUT	90184D950	2,381,000	100,000	SH	Put	SOLE		100,000	0	0
UNITEDHEALTH GROUP INC	PUT	91324P952	31,810,800	60,000	SH	Put	SOLE		60,000	0	0
UNITED THERAPEUTICS CORP DEL	COM	91307C102	10,103,844	36,333	SH		SOLE		36,333	0	0
VAXCYTE INC	COM	92243G108	2,950,268	61,528	SH		SOLE		61,528	0	0
VERA THERAPEUTICS INC	CL A	92337R101	684,448	35,372	SH		SOLE		35,372	0	0
VERASTEM INC	COM	92337C104	404,219	1,004,272	SH		SOLE		1,004,272	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	808,584	2,800	SH		SOLE		2,800	0	0
VIEWRAY INC	COM	92672L107	56,219,560	12,549,009	SH		SOLE		12,549,009	0	0
VIRIDIAN THERAPEUTICS INC	COM	92790C104	1,022,438	35,003	SH		SOLE		35,003	0	0
VIEWRAY INC	CALL	92672L907	16,576,000	3,700,000	SH	Call	SOLE		0	0	0
WM TECHNOLOGY INC	*W EXP 06/16/202	92971A117	5,000	50,000	SH		SOLE		50,000	0	0
SPDR SER TR	CALL	78464A900	8,233,600	99,200	SH	Call	SOLE		0	0	0
SPDR SER TR	PUT	78464A950	47,310,000	570,000	SH	Put	SOLE		570,000	0	0
LYRA THERAPEUTICS INC	COM	55234L105	6,773,916	2,157,298	SH		SOLE		2,157,298	0	0
MEDAVAIL HOLDINGS INC	COM	58406B103	99,462	331,761	SH		SOLE		331,761	0	0
SELECT SECTOR SPDR TR	PUT	81369Y959	29,887,000	220,000	SH	Put	SOLE		220,000	0	0