Rock Springs Capital Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
ACADIA HEALTHCARE COMPANY IN	COM	00404A109	41,305	749,500	SH		SOLE		749,500	0	0
ACHILLION PHARMACEUTICALS IN	COM	00448Q201	9,418	1,220,000	SH		SOLE		1,220,000	0	0
ACLARIS THERAPEUTICS INC	COM	00461U105	16,970	895,500	SH		SOLE		895,500	0	0
ADAPTIMMUNE THERAPEUTICS PLC	SPONDS ADR	00653A107	6,219	765,001	SH		SOLE		765,001	0	0
ADURO BIOTECH INC	COM	00739L101	5,316	415,000	SH		SOLE		415,000	0	0
ADVANCED ACCELERATOR APPLIC	SPONSORED ADS	00790T100	29,172	833,000	SH		SOLE		833,000	0	0
AETNA INC NEW	COM	00817Y108	46,176	411,000	SH		SOLE		411,000	0	0
AIMMUNE THERAPEUTICS INC	COM	00900T107	3,973	293,000	SH		SOLE		293,000	0	0
ALDER BIOPHARMACEUTICALS INC	COM	014339105	2,388	97,500	SH		SOLE		97,500	0	0
ALEXION PHARMACEUTICALS INC	COM	015351109	31,707	227,750	SH		SOLE		227,750	0	0
ALKERMES PLC	SHS	G01767105	6,650	194,500	SH		SOLE		194,500	0	0
ALLERGAN PLC	SHS	G0177J108	45,833	171,000	SH		SOLE		171,000	0	0
ALLERGAN PLC	PFD CONV SER A	G0177J116	4,585	5,000	SH		SOLE		5,000	0	0
AMGEN INC	COM	031162100	14,093	94,000	SH		SOLE		94,000	0	0
AMICUS THERAPEUTICS INC	COM	03152W109	5,184	613,500	SH		SOLE		613,500	0	0
ANACOR PHARMACEUTICALS INC	COM	032420101	9,487	177,500	SH		SOLE		177,500	0	0
ANTHEM INC	COM	036752103	16,818	121,000	SH		SOLE		121,000	0	0
ANTHERA PHARMACEUTICALS INC	COM NEW	03674U201	1,629	450,000	SH		SOLE		450,000	0	0
ARDELYX INC	COM	039697107	8,239	1,060,400	SH		SOLE		1,060,400	0	0
ASCENDIS PHARMA A S	SPONSORED ADR	04351P101	5,009	270,000	SH		SOLE		270,000	0	0
ASSEMBLY BIOSCIENCES INC	COM	045396108	1,958	390,000	SH		SOLE		390,000	0	0
ATHENAHEALTH INC	COM	04685W103	6,349	45,750	SH		SOLE		45,750	0	0
ATYR PHARMA INC	COM	002120103	1,708	433,496	SH		SOLE		433,496	0	0
AURIS MED HLDG AG	COM	H03579101	2,867	787,600	SH		SOLE		787,600	0	0
AVEXIS INC	COM	05366U100	3,889	142,758	SH		SOLE		142,758	0	0
BAXALTA INC	COM	07177M103	32,724	810,000	SH		SOLE		810,000	0	0
BEIGENE LTD	SPONSORED ADR	07725L102	6,595	225,000	SH		SOLE		225,000	0	0
BIOGEN INC	COM	09062X103	13,836	53,150	SH		SOLE		53,150	0	0
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	8,516	103,250	SH		SOLE		103,250	0	0
BLUEBIRD BIO INC	COM	09609G100	850	20,000	SH		SOLE		20,000	0	0
BRISTOL MYERS SQUIBB CO	COM	110122108	10,860	170,000	SH		SOLE		170,000	0	0
CARDIOME PHARMA CORP	COM NO PAR	14159U301	4,867	1,190,000	SH		SOLE		1,190,000	0	0
CELGENE CORP	COM	151020104	23,972	239,500	SH		SOLE		239,500	0	0
CERULEAN PHARMA INC	COM	15708Q105	1,694	625,000	SH		SOLE		625,000	0	0
CHIASMA INC	COM	16706W102	4,511	492,500	SH		SOLE		492,500	0	0
CHINA CORD BLOOD CORP	SHS	G21107100	5,342	880,000	SH		SOLE		880,000	0	0
CIDARA THERAPEUTICS INC	COM	171757107	3,175	250,000	SH		SOLE		250,000	0	0
CIGNA CORPORATION	COM	125509109	16,743	122,000	SH		SOLE		122,000	0	0
CLOVIS ONCOLOGY INC	COM	189464100	2,400	125,000	SH		SOLE		125,000	0	0
COHERUS BIOSCIENCES INC	COM	19249H103	5,987	282,000	SH		SOLE		282,000	0	0
COLLEGIUM PHARMACEUTICAL INC	COM	19459J104	20,782	1,145,000	SH		SOLE		1,145,000	0	0
COMPUGEN LTD	ORD	M25722105	4,576	820,000	SH		SOLE		820,000	0	0
COOPER COS INC	COM NEW	216648402	7,329	47,600	SH		SOLE		47,600	0	0
CORVUS PHARMACEUTICALS INC	COM	221015100	6,625	456,887	SH		SOLE		456,887	0	0
DBV TECHNOLOGIES S A	SPONSORED ADR	23306J101	2,376	73,000	SH		SOLE		73,000	0	0
DERMIRA INC	COM	24983L104	5,997	290,000	SH		SOLE		290,000	0	0
DIMENSION THERAPEUTICS INC	COM	25433V105	2,125	271,370	SH		SOLE		271,370	0	0
DYNAVAX TECHNOLOGIES CORP	COM NEW	268158201	3,175	165,000	SH		SOLE		165,000	0	0
EDWARDS LIFESCIENCES CORP	COM	28176E108	6,704	76,000	SH		SOLE		76,000	0	0
EGALET CORP	COM	28226B104	2,058	300,000	SH		SOLE		300,000	0	0
ENDOCHOICE HLDGS INC	COM	29272U103	3,074	590,000	SH		SOLE		590,000	0	0
ENVISION HEALTHCARE HLDGS IN	COM	29413U103	5,426	266,000	SH		SOLE		266,000	0	0
EPIZYME INC	COM	29428V104	7,139	589,000	SH		SOLE		589,000	0	0
FIBROGEN INC	COM	31572Q808	4,343	204,000	SH		SOLE		204,000	0	0
FIVE PRIME THERAPEUTICS INC	COM	33830X104	5,871	144,500	SH		SOLE		144,500	0	0
GALAPAGOS NV	SPON ADR	36315X101	8,782	210,000	SH		SOLE		210,000	0	0
GENOCEA BIOSCIENCES INC	COM	372427104	3,715	480,000	SH		SOLE		480,000	0	0
GILEAD SCIENCES INC	COM	375558103	30,341	330,300	SH		SOLE		330,300	0	0
GLOBAL BLOOD THERAPEUTICS IN	COM	37890U108	1,237	78,000	SH		SOLE		78,000	0	0
GW PHARMACEUTICALS PLC	ADS	36197T103	10,606	147,000	SH		SOLE		147,000	0	0
HCA HOLDINGS INC	COM	40412C101	33,562	430,000	SH		SOLE		430,000	0	0
HEALTHSOUTH CORP	COM NEW	421924309	7,827	208,000	SH		SOLE		208,000	0	0
HEARTWARE INTL INC	COM	422368100	6,064	193,000	SH		SOLE		193,000	0	0
INCYTE CORP	COM	45337C102	9,457	130,500	SH		SOLE		130,500	0	0
INFINITY PHARMACEUTICALS INC	COM	45665G303	1,423	270,000	SH		SOLE		270,000	0	0
INOVALON HLDGS INC	COM CL A	45781D101	7,914	427,300	SH		SOLE		427,300	0	0
INSMED INC	COM PAR $.01	457669307	5,702	450,000	SH		SOLE		450,000	0	0
INSYS THERAPEUTICS INC NEW	COM NEW	45824V209	5,844	365,500	SH		SOLE		365,500	0	0
INTERCEPT PHARMACEUTICALS IN	COM	45845P108	1,285	10,000	SH		SOLE		10,000	0	0
INTERSECT ENT INC	COM	46071F103	6,460	340,000	SH		SOLE		340,000	0	0
INTRA CELLULAR THERAPIES INC	COM	46116X101	5,213	187,500	SH		SOLE		187,500	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	25,244	42,000	SH		SOLE		42,000	0	0
INVITAE CORP	COM	46185L103	7,698	752,500	SH		SOLE		752,500	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	11,162	85,500	SH		SOLE		85,500	0	0
JUNO THERAPEUTICS INC	COM	48205A109	7,504	197,001	SH		SOLE		197,001	0	0
KITE PHARMA INC	COM	49803L109	3,673	80,000	SH		SOLE		80,000	0	0
LILLY ELI & CO	COM	532457108	19,875	276,000	SH		SOLE		276,000	0	0
MACROGENICS INC	COM	556099109	4,219	225,000	SH		SOLE		225,000	0	0
MCKESSON CORP	COM	58155Q103	12,187	77,500	SH		SOLE		77,500	0	0
MEDICINES CO	COM	584688105	20,079	632,000	SH		SOLE		632,000	0	0
MEDICINES CO	NOTE 2.500% 1/1	584688AE5	3,405	3,000,000	PRN		SOLE		3,000,000	0	0
MEDNAX INC	COM	58502B106	12,601	195,000	SH		SOLE		195,000	0	0
MIRNA THERAPEUTICS INC	COM	60470J103	656	150,000	SH		SOLE		150,000	0	0
NABRIVA THERAPEUTICS AG	SPONSORED ADR	62957M104	3,405	380,000	SH		SOLE		380,000	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	15,998	404,500	SH		SOLE		404,500	0	0
NIVALIS THERAPEUTICS INC	COM	65481J109	2,039	489,000	SH		SOLE		489,000	0	0
NOVADAQ TECHNOLOGIES INC	COM	66987G102	6,155	555,000	SH		SOLE		555,000	0	0
NOVAVAX INC	COM	670002104	4,399	852,500	SH		SOLE		852,500	0	0
NOVOCURE LTD	ORD SHS	G6674U108	3,103	214,316	SH		SOLE		214,316	0	0
OPHTHOTECH CORP	COM	683745103	2,177	51,500	SH		SOLE		51,500	0	0
OREXIGEN THERAPEUTICS INC	COM	686164104	930	1,653,000	SH		SOLE		1,653,000	0	0
OTONOMY INC	COM	68906L105	3,581	240,000	SH		SOLE		240,000	0	0
PACIRA PHARMACEUTICALS INC	COM	695127100	17,298	326,500	SH		SOLE		326,500	0	0
PARATEK PHARMACEUTICALS INC	COM	699374302	3,383	223,000	SH		SOLE		223,000	0	0
PENUMBRA INC	COM	70975L107	10,511	228,500	SH		SOLE		228,500	0	0
PERRIGO CO PLC	SHS	G97822103	3,838	30,000	SH		SOLE		30,000	0	0
PFIZER INC	COM	717081103	30,775	1,038,300	SH		SOLE		1,038,300	0	0
PORTOLA PHARMACEUTICALS INC	COM	737010108	3,570	175,000	SH		SOLE		175,000	0	0
PORTOLA PHARMACEUTICALS INC	COM	737010108	714	35,000	SH	Call	SOLE		35,000	0	0
PRA HEALTH SCIENCES INC	COM	69354M108	10,818	253,000	SH		SOLE		253,000	0	0
PROTEOSTASIS THERAPEUTICS IN	COM	74373B109	4,531	470,000	SH		SOLE		470,000	0	0
PROTHENA CORP PLC	SHS	G72800108	12,677	308,000	SH		SOLE		308,000	0	0
PUMA BIOTECHNOLOGY INC	COM	74587V107	925	31,500	SH		SOLE		31,500	0	0
RADIUS HEALTH INC	COM NEW	750469207	25,419	808,500	SH		SOLE		808,500	0	0
REGENERON PHARMACEUTICALS	COM	75886F107	5,947	16,500	SH		SOLE		16,500	0	0
RETROPHIN INC	COM	761299106	7,122	521,400	SH		SOLE		521,400	0	0
RIGEL PHARMACEUTICALS INC	COM NEW	766559603	3,045	1,464,050	SH		SOLE		1,464,050	0	0
RTI SURGICAL INC	COM	74975N105	7,440	1,860,000	SH		SOLE		1,860,000	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	2,557	131,000	SH		SOLE		131,000	0	0
SCYNEXIS INC	COM	811292101	2,559	635,000	SH		SOLE		635,000	0	0
SERES THERAPEUTICS INC	COM	81750R102	6,959	262,000	SH		SOLE		262,000	0	0
SOPHIRIS BIO INC	COM NEW	83578Q209	905	628,563	SH		SOLE		628,563	0	0
SPARK THERAPEUTICS INC	COM	84652J103	17,131	580,500	SH		SOLE		580,500	0	0
TANDEM DIABETES CARE INC	COM	875372104	4,899	562,500	SH		SOLE		562,500	0	0
TESARO INC	COM	881569107	16,709	379,500	SH		SOLE		379,500	0	0
TETRAPHASE PHARMACEUTICALS I	COM	88165N105	1,852	400,000	SH		SOLE		400,000	0	0
TEVA PHARMACEUTICAL INDS LTD	ADR	881624209	21,136	395,000	SH		SOLE		395,000	0	0
THERAPEUTICSMD INC	COM	88338N107	10,080	1,575,000	SH		SOLE		1,575,000	0	0
THERAVANCE BIOPHARMA INC	COM	G8807B106	12,229	650,500	SH		SOLE		650,500	0	0
THERMO FISHER SCIENTIFIC INC	COM	883556102	14,187	100,200	SH		SOLE		100,200	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	7,502	118,500	SH		SOLE		118,500	0	0
VALEANT PHARMACEUTICALS INTL	COM	91911K102	2,249	85,500	SH		SOLE		85,500	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	6,669	83,900	SH		SOLE		83,900	0	0
WALGREENS BOOTS ALLIANCE INC	COM	931427108	10,404	123,500	SH		SOLE		123,500	0	0
WELLCARE HEALTH PLANS INC	COM	94946T106	21,333	230,000	SH		SOLE		230,000	0	0
WRIGHT MED GROUP INC	NOTE 2.000% 2/1	98235TAE7	898	1,000,000	PRN		SOLE		1,000,000	0	0
WRIGHT MED GROUP N V	ORD SHS 0.03 PAR	N96617118	8,134	490,000	SH		SOLE		490,000	0	0
XENOPORT INC	COM	98411C100	4,961	1,100,000	SH		SOLE		1,100,000	0	0