COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 |
| | | VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY |
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
ABCAM PLC | ADS | 000380204 | 20,551 | 1,069,236 | SH | | SOLE | | 1,069,236 | 0 | 0 |
ACADIA HEALTHCARE COMPANY IN | COM | 00404A109 | 39,998 | 700,000 | SH | | SOLE | | 700,000 | 0 | 0 |
ACADIA PHARMACEUTICALS INC | COM | 004225108 | 27,766 | 1,076,200 | SH | | SOLE | | 1,076,200 | 0 | 0 |
ACCOLADE INC | COM | 00437E102 | 28,356 | 625,000 | SH | | SOLE | | 625,000 | 0 | 0 |
ACELRX PHARMACEUTICALS INC | COM | 00444T100 | 6,435 | 3,785,457 | SH | | SOLE | | 3,785,457 | 0 | 0 |
ACLARIS THERAPEUTICS INC | COM | 00461U105 | 89,944 | 3,569,192 | SH | | SOLE | | 3,569,192 | 0 | 0 |
ADAPTIMMUNE THERAPEUTICS PLC | SPONDS ADR | 00653A107 | 8,204 | 1,545,000 | SH | | SOLE | | 1,545,000 | 0 | 0 |
ADAPTIVE BIOTECHNOLOGIES COR | COM | 00650F109 | 26,169 | 650,000 | SH | | SOLE | | 650,000 | 0 | 0 |
AEGLEA BIOTHERAPEUTICS INC | COM | 00773J103 | 12,492 | 1,577,296 | SH | | SOLE | | 1,577,296 | 0 | 0 |
AGIOS PHARMACEUTICALS INC | COM | 00847X104 | 131,352 | 2,543,600 | SH | | SOLE | | 2,543,600 | 0 | 0 |
AKERO THERAPEUTICS INC | COM | 00973Y108 | 15,119 | 521,171 | SH | | SOLE | | 521,171 | 0 | 0 |
ALIGN TECHNOLOGY INC | COM | 016255101 | 96,122 | 177,500 | SH | | SOLE | | 177,500 | 0 | 0 |
ALLAKOS INC | COM | 01671P100 | 35,089 | 305,706 | SH | | SOLE | | 305,706 | 0 | 0 |
ALNYLAM PHARMACEUTICALS INC | COM | 02043Q107 | 42,357 | 300,000 | SH | | SOLE | | 300,000 | 0 | 0 |
AMARIN CORP PLC | SPONS ADR NEW | 023111206 | 26,051 | 4,195,000 | SH | | SOLE | | 4,195,000 | 0 | 0 |
AMICUS THERAPEUTICS INC | COM | 03152W109 | 10,004 | 1,012,506 | SH | | SOLE | | 1,012,506 | 0 | 0 |
ANAPTYSBIO INC | COM | 032724106 | 11,534 | 535,232 | SH | | SOLE | | 535,232 | 0 | 0 |
APPLIED THERAPEUTICS INC | COM | 03828A101 | 13,160 | 701,680 | SH | | SOLE | | 701,680 | 0 | 0 |
ARDELYX INC | COM | 039697107 | 34,269 | 5,176,561 | SH | | SOLE | | 5,176,561 | 0 | 0 |
ARGENX SE | SPONSORED ADR | 04016X101 | 82,617 | 300,000 | SH | | SOLE | | 300,000 | 0 | 0 |
ARVINAS INC | COM | 04335A105 | 41,101 | 621,800 | SH | | SOLE | | 621,800 | 0 | 0 |
ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 | 30,093 | 233,500 | SH | | SOLE | | 233,500 | 0 | 0 |
ASTRAZENECA PLC | SPONSORED ADR | 046353108 | 32,318 | 650,000 | SH | | SOLE | | 650,000 | 0 | 0 |
ATEA PHARMACEUTICALS INC | COM | 04683R106 | 104,660 | 1,694,903 | SH | | SOLE | | 1,694,903 | 0 | 0 |
ATHIRA PHARMA INC | COM | 04746L104 | 14,503 | 788,202 | SH | | SOLE | | 788,202 | 0 | 0 |
ATRECA INC | CL A COM | 04965G109 | 6,959 | 453,930 | SH | | SOLE | | 453,930 | 0 | 0 |
AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 10,149 | 781,569 | SH | | SOLE | | 781,569 | 0 | 0 |
BAXTER INTL INC | COM | 071813109 | 11,808 | 140,000 | SH | | SOLE | | 140,000 | 0 | 0 |
BCLS ACQUISITION CORP | COM CL A | G0904B105 | 3,266 | 309,000 | SH | | SOLE | | 309,000 | 0 | 0 |
BEIGENE LTD | SPONSORED ADR | 07725L102 | 69,616 | 200,000 | SH | | SOLE | | 200,000 | 0 | 0 |
BIOGEN INC | COM | 09062X103 | 31,752 | 113,500 | SH | | SOLE | | 113,500 | 0 | 0 |
BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 19,142 | 253,500 | SH | | SOLE | | 253,500 | 0 | 0 |
BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 72,605 | 746,732 | SH | | SOLE | | 746,732 | 0 | 0 |
BOLT BIOTHERAPEUTICS INC | COM | 097702104 | 51,315 | 1,559,248 | SH | | SOLE | | 1,559,248 | 0 | 0 |
BOSTON SCIENTIFIC CORP | COM | 101137107 | 30,920 | 800,000 | SH | | SOLE | | 800,000 | 0 | 0 |
CEREVEL THERAPEUTICS HLDNG I | COM | 15678U128 | 13,800 | 1,005,100 | SH | | SOLE | | 1,005,100 | 0 | 0 |
CHIASMA INC | COM | 16706W102 | 6,806 | 2,174,583 | SH | | SOLE | | 2,174,583 | 0 | 0 |
CHINOOK THERAPEUTICS INC | COM | 16961L106 | 10,459 | 673,049 | SH | | SOLE | | 673,049 | 0 | 0 |
COLLEGIUM PHARMACEUTICAL INC | COM | 19459J104 | 21,804 | 920,000 | SH | | SOLE | | 920,000 | 0 | 0 |
COMPUGEN LTD | ORD | M25722105 | 10,475 | 1,219,488 | SH | | SOLE | | 1,219,488 | 0 | 0 |
CONMED CORP | COM | 207410101 | 11,111 | 85,085 | SH | | SOLE | | 85,085 | 0 | 0 |
CONNECT BIOPHARMA HLDGS LTD | ADS | 207523101 | 2,204 | 119,114 | SH | | SOLE | | 119,114 | 0 | 0 |
CONSTELLATION PHARMCETICLS I | COM | 210373106 | 5,426 | 232,000 | SH | | SOLE | | 232,000 | 0 | 0 |
COVETRUS INC | COM | 22304C100 | 41,958 | 1,400,000 | SH | | SOLE | | 1,400,000 | 0 | 0 |
CULLINAN ONCOLOGY INC | COM | 230031106 | 44,833 | 1,075,912 | SH | | SOLE | | 1,075,912 | 0 | 0 |
CYTOKINETICS INC | NOTE 4.000%11/1 | 23282WAA8 | 19,094 | 8,000,000 | PRN | | SOLE | | 8,000,000 | 0 | 0 |
DESIGN THERAPEUTICS INC | COM | 25056L103 | 9,785 | 327,250 | SH | | SOLE | | 327,250 | 0 | 0 |
DEXCOM INC | COM | 252131107 | 5,391 | 15,000 | SH | | SOLE | | 15,000 | 0 | 0 |
DYNAVAX TECHNOLOGIES CORP | COM NEW | 268158201 | 16,303 | 1,658,520 | SH | | SOLE | | 1,658,520 | 0 | 0 |
EARGO INC | COM | 270087109 | 42,541 | 851,671 | SH | | SOLE | | 851,671 | 0 | 0 |
EDWARDS LIFESCIENCES CORP | COM | 28176E108 | 48,678 | 582,000 | SH | | SOLE | | 582,000 | 0 | 0 |
ENCOMPASS HEALTH CORP | COM | 29261A100 | 40,950 | 500,000 | SH | | SOLE | | 500,000 | 0 | 0 |
EPIZYME INC | COM | 29428V104 | 24,414 | 2,802,954 | SH | | SOLE | | 2,802,954 | 0 | 0 |
ESSA PHARMA INC | COM NEW | 29668H708 | 14,613 | 503,035 | SH | | SOLE | | 503,035 | 0 | 0 |
EUCRATES BIOMEDICAL ACQU COR | UNIT 10/23/2027 | G3141W114 | 2,063 | 206,000 | SH | | SOLE | | 206,000 | 0 | 0 |
EVOLENT HEALTH INC | CL A | 30050B101 | 29,189 | 1,445,000 | SH | | SOLE | | 1,445,000 | 0 | 0 |
EXACT SCIENCES CORP | COM | 30063P105 | 75,115 | 570,000 | SH | | SOLE | | 570,000 | 0 | 0 |
FATE THERAPEUTICS INC | COM | 31189P102 | 5,772 | 70,000 | SH | | SOLE | | 70,000 | 0 | 0 |
FIBROGEN INC | COM | 31572Q808 | 10,853 | 312,687 | SH | | SOLE | | 312,687 | 0 | 0 |
FIVE PRIME THERAPEUTICS INC | COM | 33830X104 | 100,233 | 2,660,822 | SH | | SOLE | | 2,660,822 | 0 | 0 |
FRESHPET INC | COM | 358039105 | 80,437 | 506,500 | SH | | SOLE | | 506,500 | 0 | 0 |
FS DEVELOPMENT CORP II | COM CL A | 30318F100 | 2,085 | 209,332 | SH | | SOLE | | 209,332 | 0 | 0 |
FUSION PHARMACEUTICALS INC | COM | 36118A100 | 10,166 | 948,327 | SH | | SOLE | | 948,327 | 0 | 0 |
GALAPAGOS NV | SPON ADR | 36315X101 | 12,720 | 165,000 | SH | | SOLE | | 165,000 | 0 | 0 |
GALERA THERAPEUTICS INC | COM | 36338D108 | 5,012 | 568,252 | SH | | SOLE | | 568,252 | 0 | 0 |
GAMIDA CELL LTD | SHS | M47364100 | 16,991 | 2,100,300 | SH | | SOLE | | 2,100,300 | 0 | 0 |
GOSSAMER BIO INC | NOTE 5.000% 6/0 | 38341PAA0 | 13,977 | 15,573,000 | PRN | | SOLE | | 15,573,000 | 0 | 0 |
GUARDANT HEALTH INC | COM | 40131M109 | 30,530 | 200,000 | SH | | SOLE | | 200,000 | 0 | 0 |
HCA HEALTHCARE INC | COM | 40412C101 | 84,753 | 450,000 | SH | | SOLE | | 450,000 | 0 | 0 |
HEALTH CATALYST INC | COM | 42225T107 | 36,714 | 785,000 | SH | | SOLE | | 785,000 | 0 | 0 |
HELIX ACQUISITION CORP | COM CL A | G4444C102 | 1,576 | 154,500 | SH | | SOLE | | 154,500 | 0 | 0 |
HORIZON THERAPEUTICS PUB L | SHS | G46188101 | 57,525 | 625,000 | SH | | SOLE | | 625,000 | 0 | 0 |
HUMANA INC | COM | 444859102 | 126,194 | 301,000 | SH | | SOLE | | 301,000 | 0 | 0 |
IDEXX LABS INC | COM | 45168D104 | 88,076 | 180,000 | SH | | SOLE | | 180,000 | 0 | 0 |
IMMUNOCORE HLDGS PLC | ADS | 45258D105 | 97,583 | 2,292,285 | SH | | SOLE | | 2,292,285 | 0 | 0 |
INNOVAGE HLDG CORP | COM | 45784A104 | 12,250 | 475,000 | SH | | SOLE | | 475,000 | 0 | 0 |
INOZYME PHARMA INC | COM | 45790W108 | 16,392 | 827,900 | SH | | SOLE | | 827,900 | 0 | 0 |
INSPIRE MED SYS INC | COM | 457730109 | 20,699 | 100,000 | SH | | SOLE | | 100,000 | 0 | 0 |
INSULET CORP | COM | 45784P101 | 96,801 | 371,000 | SH | | SOLE | | 371,000 | 0 | 0 |
INTERSECT ENT INC | COM | 46071F103 | 22,555 | 1,080,200 | SH | | SOLE | | 1,080,200 | 0 | 0 |
INTUITIVE SURGICAL INC | COM NEW | 46120E602 | 88,673 | 120,000 | SH | | SOLE | | 120,000 | 0 | 0 |
INVITAE CORP | COM | 46185L103 | 84,596 | 2,213,977 | SH | | SOLE | | 2,213,977 | 0 | 0 |
IRHYTHM TECHNOLOGIES INC | COM | 450056106 | 60,056 | 432,496 | SH | | SOLE | | 432,496 | 0 | 0 |
JIYA ACQUISITION CORP | COM CL A | 47760M102 | 2,029 | 206,200 | SH | | SOLE | | 206,200 | 0 | 0 |
KARUNA THERAPEUTICS INC | COM | 48576A100 | 44,336 | 368,764 | SH | | SOLE | | 368,764 | 0 | 0 |
KINNATE BIOPHARMA INC | COM | 49705R105 | 10,170 | 326,386 | SH | | SOLE | | 326,386 | 0 | 0 |
KURA ONCOLOGY INC | COM | 50127T109 | 20,073 | 710,035 | SH | | SOLE | | 710,035 | 0 | 0 |
KYMERA THERAPEUTICS INC | COM | 501575104 | 24,162 | 621,777 | SH | | SOLE | | 621,777 | 0 | 0 |
LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | 9,072 | 312,618 | SH | | SOLE | | 312,618 | 0 | 0 |
LIFESCI ACQUISITION II CORP | COM | 53229E103 | 2,091 | 206,200 | SH | | SOLE | | 206,200 | 0 | 0 |
MACROGENICS INC | COM | 556099109 | 12,532 | 393,479 | SH | | SOLE | | 393,479 | 0 | 0 |
MADRIGAL PHARMACEUTICALS INC | COM | 558868105 | 30,237 | 258,500 | SH | | SOLE | | 258,500 | 0 | 0 |
MEREO BIOPHARMA GROUP PLC | ADS | 589492107 | 15,148 | 4,494,869 | SH | | SOLE | | 4,494,869 | 0 | 0 |
MERSANA THERAPEUTICS INC | COM | 59045L106 | 44,902 | 2,775,127 | SH | | SOLE | | 2,775,127 | 0 | 0 |
MIRATI THERAPEUTICS INC | COM | 60468T105 | 55,441 | 323,647 | SH | | SOLE | | 323,647 | 0 | 0 |
MIRUM PHARMACEUTICALS INC | COM | 604749101 | 29,785 | 1,502,800 | SH | | SOLE | | 1,502,800 | 0 | 0 |
NEUROCRINE BIOSCIENCES INC | COM | 64125C109 | 98,709 | 1,015,000 | SH | | SOLE | | 1,015,000 | 0 | 0 |
NEUROCRINE BIOSCIENCES INC | NOTE 2.250% 5/1 | 64125CAD1 | 1,354 | 1,000,000 | PRN | | SOLE | | 1,000,000 | 0 | 0 |
NEVRO CORP | COM | 64157F103 | 67,658 | 485,000 | SH | | SOLE | | 485,000 | 0 | 0 |
NEVRO CORP | NOTE 2.750% 4/0 | 64157FAC7 | 771 | 500,000 | PRN | | SOLE | | 500,000 | 0 | 0 |
NGM BIOPHARMACEUTICALS INC | COM | 62921N105 | 10,605 | 364,800 | SH | | SOLE | | 364,800 | 0 | 0 |
NKARTA INC | COM | 65487U108 | 16,182 | 491,848 | SH | | SOLE | | 491,848 | 0 | 0 |
NOVAVAX INC | COM NEW | 670002401 | 83,584 | 461,000 | SH | | SOLE | | 461,000 | 0 | 0 |
NOVOCURE LTD | ORD SHS | G6674U108 | 23,132 | 175,000 | SH | | SOLE | | 175,000 | 0 | 0 |
NURIX THERAPEUTICS INC | COM | 67080M103 | 9,667 | 310,950 | SH | | SOLE | | 310,950 | 0 | 0 |
NUVATION BIO INC | *W EXP 07/07/202 | 67080N119 | 358 | 134,028 | SH | | SOLE | | 134,028 | 0 | 0 |
NUVATION BIO INC | COM CL A | 67080N101 | 4,202 | 402,088 | SH | | SOLE | | 402,088 | 0 | 0 |
OAK STR HEALTH INC | COM | 67181A107 | 20,351 | 375,000 | SH | | SOLE | | 375,000 | 0 | 0 |
OLINK HLDG AB | SPONSORED ADS | 680710100 | 14,400 | 400,000 | SH | | SOLE | | 400,000 | 0 | 0 |
ORION ACQUISITION CORP | UNIT 02/19/2026 | 68626A207 | 10,000 | 1,000,000 | SH | | SOLE | | 1,000,000 | 0 | 0 |
PACIRA BIOSCIENCES INC | COM | 695127100 | 71,842 | 1,025,000 | SH | | SOLE | | 1,025,000 | 0 | 0 |
PACIRA BIOSCIENCES INC | NOTE 2.375% 4/0 | 695127AD2 | 1,211 | 1,000,000 | PRN | | SOLE | | 1,000,000 | 0 | 0 |
PARATEK PHARMACEUTICALS INC | COM | 699374302 | 11,894 | 1,684,714 | SH | | SOLE | | 1,684,714 | 0 | 0 |
PENUMBRA INC | COM | 70975L107 | 39,911 | 147,500 | SH | | SOLE | | 147,500 | 0 | 0 |
PHASEBIO PHARMACEUTICALS INC | COM | 717224109 | 5,377 | 1,553,974 | SH | | SOLE | | 1,553,974 | 0 | 0 |
PHREESIA INC | COM | 71944F106 | 44,285 | 850,000 | SH | | SOLE | | 850,000 | 0 | 0 |
POPULATION HEALTH INVS CO IN | UNIT 99/99/9999 | G71716123 | 2,020 | 201,044 | SH | | SOLE | | 201,044 | 0 | 0 |
POSEIDA THERAPEUTICS INC | COM | 73730P108 | 2,767 | 289,754 | SH | | SOLE | | 289,754 | 0 | 0 |
PPD INC | COM | 69355F102 | 25,542 | 675,000 | SH | | SOLE | | 675,000 | 0 | 0 |
PRELUDE THERAPEUTICS INC | COM | 74065P101 | 16,387 | 378,195 | SH | | SOLE | | 378,195 | 0 | 0 |
PROMETHEUS BIOSCIENCES INC | COM | 74349U108 | 10,497 | 574,858 | SH | | SOLE | | 574,858 | 0 | 0 |
PROTARA THERAPEUTICS INC | COM STK | 74365U107 | 10,860 | 689,942 | SH | | SOLE | | 689,942 | 0 | 0 |
PROTHENA CORP PLC | SHS | G72800108 | 29,061 | 1,156,900 | SH | | SOLE | | 1,156,900 | 0 | 0 |
PULMONX CORP | COM | 745848101 | 27,101 | 592,500 | SH | | SOLE | | 592,500 | 0 | 0 |
RADIUS HEALTH INC | NOTE 3.000% 9/0 | 750469AA6 | 1,401 | 1,500,000 | PRN | | SOLE | | 1,500,000 | 0 | 0 |
RELAY THERAPEUTICS INC | COM | 75943R102 | 8,716 | 252,127 | SH | | SOLE | | 252,127 | 0 | 0 |
RETROPHIN INC | NOTE 2.500% 9/1 | 761299AB2 | 3,360 | 3,250,000 | PRN | | SOLE | | 3,250,000 | 0 | 0 |
RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 12,747 | 599,280 | SH | | SOLE | | 599,280 | 0 | 0 |
RIGEL PHARMACEUTICALS INC | COM NEW | 766559603 | 16,218 | 4,742,000 | SH | | SOLE | | 4,742,000 | 0 | 0 |
ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 17,884 | 403,070 | SH | | SOLE | | 403,070 | 0 | 0 |
ROYALTY PHARMA PLC | SHS CLASS A | G7709Q104 | 3,490 | 80,000 | SH | | SOLE | | 80,000 | 0 | 0 |
SAREPTA THERAPEUTICS INC | COM | 803607100 | 24,502 | 328,750 | SH | | SOLE | | 328,750 | 0 | 0 |
SEAGEN INC | COM | 81181C104 | 34,715 | 250,000 | SH | | SOLE | | 250,000 | 0 | 0 |
SHATTUCK LABS INC | COM | 82024L103 | 11,360 | 388,499 | SH | | SOLE | | 388,499 | 0 | 0 |
SHOCKWAVE MED INC | COM | 82489T104 | 28,657 | 220,000 | SH | | SOLE | | 220,000 | 0 | 0 |
SIERRA ONCOLOGY INC | COM NEW | 82640U404 | 17,529 | 1,017,358 | SH | | SOLE | | 1,017,358 | 0 | 0 |
SPERO THERAPEUTICS INC | COM | 84833T103 | 14,218 | 965,928 | SH | | SOLE | | 965,928 | 0 | 0 |
SPRUCE BIOSCIENCES INC | COM | 85209E109 | 26,216 | 1,579,301 | SH | | SOLE | | 1,579,301 | 0 | 0 |
TELEFLEX INCORPORATED | COM | 879369106 | 54,010 | 130,000 | SH | | SOLE | | 130,000 | 0 | 0 |
TG THERAPEUTICS INC | COM | 88322Q108 | 12,846 | 266,520 | SH | | SOLE | | 266,520 | 0 | 0 |
THERAVANCE BIOPHARMA INC | COM | G8807B106 | 13,932 | 682,600 | SH | | SOLE | | 682,600 | 0 | 0 |
THERAVANCE BIOPHARMA INC | NOTE 3.250%11/0 | 88339KAA0 | 1,526 | 1,500,000 | PRN | | SOLE | | 1,500,000 | 0 | 0 |
TRANSLATE BIO INC | COM | 89374L104 | 10,717 | 649,900 | SH | | SOLE | | 649,900 | 0 | 0 |
TRAVERE THERAPEUTICS INC | COM | 89422G107 | 36,845 | 1,475,564 | SH | | SOLE | | 1,475,564 | 0 | 0 |
TRILLIUM THERAPEUTICS INC | COM NEW | 89620X506 | 6,667 | 620,800 | SH | | SOLE | | 620,800 | 0 | 0 |
TURMERIC ACQUISITION CORP | UNIT 10/08/2025 | G9127T116 | 2,060 | 206,000 | SH | | SOLE | | 206,000 | 0 | 0 |
ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | 51,237 | 450,000 | SH | | SOLE | | 450,000 | 0 | 0 |
UNITEDHEALTH GROUP INC | COM | 91324P102 | 102,319 | 275,000 | SH | | SOLE | | 275,000 | 0 | 0 |
WEST PHARMACEUTICAL SVSC INC | COM | 955306105 | 8,031 | 28,500 | SH | | SOLE | | 28,500 | 0 | 0 |
XENON PHARMACEUTICALS INC | COM | 98420N105 | 10,248 | 572,500 | SH | | SOLE | | 572,500 | 0 | 0 |
ZAI LAB LTD | ADR | 98887Q104 | 124,557 | 933,500 | SH | | SOLE | | 933,500 | 0 | 0 |