Rock Springs Capital Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
AADI BIOSCIENCES INC	COM	00032Q104	22,459	764,701	SH		SOLE		764,701	0	0
ABCAM PLC	ADS	000380204	23,262	1,147,588	SH		SOLE		1,147,588	0	0
ACADIA HEALTHCARE COMPANY IN	COM	00404A109	45,284	710,000	SH		SOLE		710,000	0	0
ACCOLADE INC	COM	00437E102	38,923	923,000	SH		SOLE		923,000	0	0
ACELRX PHARMACEUTICALS INC	COM	00444T100	3,896	3,819,402	SH		SOLE		3,819,402	0	0
ACLARIS THERAPEUTICS INC	COM	00461U105	68,458	3,803,232	SH		SOLE		3,803,232	0	0
ACUMEN PHARMACEUTICALS INC	COM	00509G209	23,467	1,579,191	SH		SOLE		1,579,191	0	0
ADAPTIMMUNE THERAPEUTICS PLC	SPONDS ADR	00653A107	11,321	2,189,788	SH		SOLE		2,189,788	0	0
AEGLEA BIOTHERAPEUTICS INC	COM	00773J103	12,540	1,577,296	SH		SOLE		1,577,296	0	0
AGILON HEALTH INC	COM	00857U107	185,436	7,075,000	SH		SOLE		7,075,000	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	117,968	2,556,179	SH		SOLE		2,556,179	0	0
AKERO THERAPEUTICS INC	COM	00973Y108	12,710	568,701	SH		SOLE		568,701	0	0
ALIGN TECHNOLOGY INC	COM	016255101	133,086	200,000	SH		SOLE		200,000	0	0
ALLAKOS INC	COM	01671P100	32,365	305,706	SH		SOLE		305,706	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	58,720	311,000	SH		SOLE		311,000	0	0
AMARIN CORP PLC	SPONS ADR NEW	023111206	22,032	4,320,000	SH		SOLE		4,320,000	0	0
AMICUS THERAPEUTICS INC	COM	03152W109	9,669	1,012,506	SH		SOLE		1,012,506	0	0
AMRYT PHARMA PLC	SPONSORED ADS	03217L106	15,601	1,295,225	SH		SOLE		1,295,225	0	0
ANAPTYSBIO INC	COM	032724106	14,532	535,832	SH		SOLE		535,832	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	872	26,458	SH		SOLE		26,458	0	0
APPLIED THERAPEUTICS INC	COM	03828A101	11,648	701,680	SH		SOLE		701,680	0	0
ARGENX SE	SPONSORED ADR	04016X101	95,130	315,000	SH		SOLE		315,000	0	0
ARVINAS INC	COM	04335A105	47,459	577,500	SH		SOLE		577,500	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	63,756	400,000	SH		SOLE		400,000	0	0
ATAI LIFE SCIENCES NV	SHS	N0731H103	4,698	317,628	SH		SOLE		317,628	0	0
ATEA PHARMACEUTICALS INC	COM	04683R106	26,306	750,307	SH		SOLE		750,307	0	0
ATHIRA PHARMA INC	COM	04746L104	5,180	552,252	SH		SOLE		552,252	0	0
ATRECA INC	CL A COM	04965G109	2,865	459,830	SH		SOLE		459,830	0	0
AURINIA PHARMACEUTICALS INC	COM	05156V102	13,572	613,269	SH		SOLE		613,269	0	0
BAXTER INTL INC	COM	071813109	36,194	450,000	SH		SOLE		450,000	0	0
BCLS ACQUISITION CORP	COM CL A	G0904B105	3,078	309,000	SH		SOLE		309,000	0	0
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	19,593	253,500	SH		SOLE		253,500	0	0
BIOMEA FUSION INC	COM	09077A106	13,952	1,165,582	SH		SOLE		1,165,582	0	0
BLUEPRINT MEDICINES CORP	COM	09627Y109	87,353	849,659	SH		SOLE		849,659	0	0
BOLT BIOTHERAPEUTICS INC	COM	097702104	20,863	1,649,248	SH		SOLE		1,649,248	0	0
BRIGHT HEALTH GROUP INC	COM	10920V107	14,402	1,765,000	SH		SOLE		1,765,000	0	0
CEREVEL THERAPEUTICS HLDNG I	COM	15678U128	47,217	1,600,589	SH		SOLE		1,600,589	0	0
CHINOOK THERAPEUTICS INC	COM	16961L106	8,781	688,149	SH		SOLE		688,149	0	0
COLLEGIUM PHARMACEUTICAL INC	COM	19459J104	17,766	900,000	SH		SOLE		900,000	0	0
COMPUGEN LTD	ORD	M25722105	7,664	1,283,790	SH		SOLE		1,283,790	0	0
CONMED CORP	COM	207410101	21,260	162,500	SH		SOLE		162,500	0	0
COVETRUS INC	COM	22304C100	29,450	1,623,500	SH		SOLE		1,623,500	0	0
CULLINAN ONCOLOGY INC	COM	230031106	24,283	1,075,912	SH		SOLE		1,075,912	0	0
CYTOKINETICS INC	NOTE 4.000%11/1	23282WAA8	28,316	8,000,000	PRN		SOLE		8,000,000	0	0
DAY ONE BIOPHARMACEUTICALS I	COM	23954D109	8,933	376,439	SH		SOLE		376,439	0	0
DESIGN THERAPEUTICS INC	COM	25056L103	4,907	334,050	SH		SOLE		334,050	0	0
DEXCOM INC	COM	252131107	25,429	46,500	SH		SOLE		46,500	0	0
DYNAVAX TECHNOLOGIES CORP	COM NEW	268158201	27,469	1,429,921	SH		SOLE		1,429,921	0	0
EARGO INC	COM	270087109	6,562	975,000	SH		SOLE		975,000	0	0
EDAP TMS S A	SPONSORED ADR	268311107	4,855	760,900	SH		SOLE		760,900	0	0
EDWARDS LIFESCIENCES CORP	COM	28176E108	65,888	582,000	SH		SOLE		582,000	0	0
ENCOMPASS HEALTH CORP	COM	29261A100	37,520	500,000	SH		SOLE		500,000	0	0
EPIZYME INC	COM	29428V104	18,401	3,593,885	SH		SOLE		3,593,885	0	0
ESSA PHARMA INC	COM NEW	29668H708	4,064	508,044	SH		SOLE		508,044	0	0
EUCRATES BIOMEDICAL ACQU COR	UNIT 10/23/2027	G3141W114	2,050	206,000	SH		SOLE		206,000	0	0
EVOLENT HEALTH INC	CL A	30050B101	58,125	1,875,000	SH		SOLE		1,875,000	0	0
EXACT SCIENCES CORP	COM	30063P105	54,407	570,000	SH		SOLE		570,000	0	0
FATE THERAPEUTICS INC	COM	31189P102	6,520	110,000	SH		SOLE		110,000	0	0
FRESHPET INC	COM	358039105	75,198	527,000	SH		SOLE		527,000	0	0
FS DEVELOPMENT CORP II	COM CL A	30318F100	2,083	209,332	SH		SOLE		209,332	0	0
F-STAR THERAPEUTICS INC	COM	30315R107	7,717	1,054,232	SH		SOLE		1,054,232	0	0
FULCRUM THERAPEUTICS INC	COM	359616109	12,844	455,290	SH		SOLE		455,290	0	0
FUSION PHARMACEUTICALS INC	COM	36118A100	7,511	948,327	SH		SOLE		948,327	0	0
GALERA THERAPEUTICS INC	COM	36338D108	4,603	568,252	SH		SOLE		568,252	0	0
GAMIDA CELL LTD	SHS	M47364100	8,418	2,147,400	SH		SOLE		2,147,400	0	0
GOSSAMER BIO INC	NOTE 5.000% 6/0	38341PAA0	16,253	15,573,000	PRN		SOLE		15,573,000	0	0
GRAPHITE BIO INC	COM	38870X104	34,037	2,076,710	SH		SOLE		2,076,710	0	0
GUARDANT HEALTH INC	COM	40131M109	25,002	200,000	SH		SOLE		200,000	0	0
HCA HEALTHCARE INC	COM	40412C101	109,224	450,000	SH		SOLE		450,000	0	0
HEALTH CATALYST INC	COM	42225T107	42,509	850,000	SH		SOLE		850,000	0	0
HELIX ACQUISITION CORP	COM CL A	G4444C102	1,537	154,500	SH		SOLE		154,500	0	0
HORIZON THERAPEUTICS PUB L	SHS	G46188101	76,897	702,000	SH		SOLE		702,000	0	0
HUMANA INC	COM	444859102	133,089	342,000	SH		SOLE		342,000	0	0
ICOSAVAX INC	COM	45114M109	21,725	734,215	SH		SOLE		734,215	0	0
IDEXX LABS INC	COM	45168D104	111,942	180,000	SH		SOLE		180,000	0	0
IMARA INC	COM	45249V107	3,383	829,102	SH		SOLE		829,102	0	0
IMMUNEERING CORP	CLASS A COM	45254E107	28,935	1,089,816	SH		SOLE		1,089,816	0	0
IMMUNOCORE HLDGS PLC	ADS	45258D105	90,642	2,445,155	SH		SOLE		2,445,155	0	0
INNOVAGE HLDG CORP	COM	45784A104	3,470	525,000	SH		SOLE		525,000	0	0
INOZYME PHARMA INC	COM	45790W108	9,852	850,015	SH		SOLE		850,015	0	0
INSULET CORP	COM	45784P101	124,369	437,566	SH		SOLE		437,566	0	0
INTERSECT ENT INC	COM	46071F103	33,184	1,220,000	SH		SOLE		1,220,000	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	119,298	120,000	SH		SOLE		120,000	0	0
INVITAE CORP	COM	46185L103	74,084	2,605,829	SH		SOLE		2,605,829	0	0
IRHYTHM TECHNOLOGIES INC	COM	450056106	26,235	448,000	SH		SOLE		448,000	0	0
JIYA ACQUISITION CORP	COM CL A	47760M102	2,010	206,200	SH		SOLE		206,200	0	0
KARUNA THERAPEUTICS INC	COM	48576A100	47,943	391,917	SH		SOLE		391,917	0	0
KINNATE BIOPHARMA INC	COM	49705R105	7,665	332,986	SH		SOLE		332,986	0	0
KURA ONCOLOGY INC	COM	50127T109	15,405	822,500	SH		SOLE		822,500	0	0
KYMERA THERAPEUTICS INC	COM	501575104	43,052	732,927	SH		SOLE		732,927	0	0
LEAP THERAPEUTICS INC	COM	52187K101	14,068	3,508,270	SH		SOLE		3,508,270	0	0
LEGEND BIOTECH CORP	SPONSORED ADS	52490G102	15,937	315,218	SH		SOLE		315,218	0	0
LIFESTANCE HEALTH GROUP INC	COM	53228F101	24,469	1,687,500	SH		SOLE		1,687,500	0	0
MACROGENICS INC	COM	556099109	13,440	641,816	SH		SOLE		641,816	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	20,945	262,500	SH		SOLE		262,500	0	0
MEREO BIOPHARMA GROUP PLC	ADS	589492107	11,696	4,832,978	SH		SOLE		4,832,978	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	28,485	3,020,702	SH		SOLE		3,020,702	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	62,540	353,514	SH		SOLE		353,514	0	0
MIRUM PHARMACEUTICALS INC	COM	604749101	30,390	1,525,623	SH		SOLE		1,525,623	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	100,849	1,051,500	SH		SOLE		1,051,500	0	0
NEUROCRINE BIOSCIENCES INC	NOTE 2.250% 5/1	64125CAD1	1,336	1,000,000	PRN		SOLE		1,000,000	0	0
NEVRO CORP	COM	64157F103	73,983	635,700	SH		SOLE		635,700	0	0
NEVRO CORP	NOTE 2.750% 4/0	64157FAC7	675	500,000	PRN		SOLE		500,000	0	0
NKARTA INC	COM	65487U108	13,993	503,148	SH		SOLE		503,148	0	0
NOVAVAX INC	COM NEW	670002401	94,326	455,000	SH		SOLE		455,000	0	0
NOVOCURE LTD	ORD SHS	G6674U108	20,330	175,000	SH		SOLE		175,000	0	0
NURIX THERAPEUTICS INC	COM	67080M103	9,541	318,450	SH		SOLE		318,450	0	0
NUVATION BIO INC	*W EXP 07/07/202	67080N119	343	134,028	SH		SOLE		134,028	0	0
NUVATION BIO INC	COM CL A	67080N101	2,352	236,609	SH		SOLE		236,609	0	0
OAK STR HEALTH INC	COM	67181A107	18,756	441,000	SH		SOLE		441,000	0	0
OLINK HLDG AB	SPONSORED ADS	680710100	12,246	505,000	SH		SOLE		505,000	0	0
ORION ACQUISITION CORP	UNIT 02/19/2026	68626A207	9,895	1,000,000	SH		SOLE		1,000,000	0	0
PACIRA BIOSCIENCES INC	COM	695127100	56,000	1,000,000	SH		SOLE		1,000,000	0	0
PACIRA BIOSCIENCES INC	NOTE 2.375% 4/0	695127AD2	1,038	1,000,000	PRN		SOLE		1,000,000	0	0
PARATEK PHARMACEUTICALS INC	COM	699374302	8,092	1,665,014	SH		SOLE		1,665,014	0	0
PENUMBRA INC	COM	70975L107	39,309	147,500	SH		SOLE		147,500	0	0
PHASEBIO PHARMACEUTICALS INC	COM	717224109	5,734	1,843,764	SH		SOLE		1,843,764	0	0
PHREESIA INC	COM	71944F106	59,849	970,000	SH		SOLE		970,000	0	0
POPULATION HEALTH INVS CO IN	UNIT 99/99/9999	G71716123	2,011	201,044	SH		SOLE		201,044	0	0
POSEIDA THERAPEUTICS INC	COM	73730P108	2,112	289,754	SH		SOLE		289,754	0	0
PRELUDE THERAPEUTICS INC	COM	74065P101	11,324	362,359	SH		SOLE		362,359	0	0
PROMETHEUS BIOSCIENCES INC	COM	74349U108	14,466	610,136	SH		SOLE		610,136	0	0
PROTHENA CORP PLC	SHS	G72800108	50,604	710,430	SH		SOLE		710,430	0	0
PULMONX CORP	COM	745848101	25,186	700,000	SH		SOLE		700,000	0	0
RADIUS HEALTH INC	NOTE 3.000% 9/0	750469AA6	1,370	1,500,000	PRN		SOLE		1,500,000	0	0
RELAY THERAPEUTICS INC	COM	75943R102	14,805	469,560	SH		SOLE		469,560	0	0
RENEO PHARMACEUTICALS INC	COM	75974E103	8,517	1,143,185	SH		SOLE		1,143,185	0	0
RHYTHM PHARMACEUTICALS INC	COM	76243J105	7,995	612,180	SH		SOLE		612,180	0	0
RIGEL PHARMACEUTICALS INC	COM NEW	766559603	17,400	4,793,400	SH		SOLE		4,793,400	0	0
ROCKET PHARMACEUTICALS INC	COM	77313F106	12,054	403,270	SH		SOLE		403,270	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	32,368	350,000	SH		SOLE		350,000	0	0
SEAGEN INC	COM	81181C104	42,450	250,000	SH		SOLE		250,000	0	0
SHATTUCK LABS INC	COM	82024L103	6,389	313,499	SH		SOLE		313,499	0	0
SHOCKWAVE MED INC	COM	82489T104	45,294	220,000	SH		SOLE		220,000	0	0
SIERRA ONCOLOGY INC	COM NEW	82640U404	28,803	1,313,997	SH		SOLE		1,313,997	0	0
SPERO THERAPEUTICS INC	COM	84833T103	17,334	941,543	SH		SOLE		941,543	0	0
SPRUCE BIOSCIENCES INC	COM	85209E109	9,722	1,617,601	SH		SOLE		1,617,601	0	0
TELEFLEX INCORPORATED	COM	879369106	48,952	130,000	SH		SOLE		130,000	0	0
TEMPEST THERAPEUTICS INC	COM	87978U108	4,488	310,161	SH		SOLE		310,161	0	0
THERAVANCE BIOPHARMA INC	COM	G8807B106	5,088	687,500	SH		SOLE		687,500	0	0
THERAVANCE BIOPHARMA INC	NOTE 3.250%11/0	88339KAA0	1,391	1,500,000	PRN		SOLE		1,500,000	0	0
TRAVERE THERAPEUTICS INC	COM	89422G107	36,298	1,496,817	SH		SOLE		1,496,817	0	0
TRAVERE THERAPEUTICS INC	NOTE 2.500% 9/1	761299AB2	3,276	3,250,000	PRN		SOLE		3,250,000	0	0
TRILLIUM THERAPEUTICS INC	COM NEW	89620X506	11,036	628,500	SH		SOLE		628,500	0	0
TURMERIC ACQUISITION CORP	UNIT 10/08/2025	G9127T116	2,046	206,000	SH		SOLE		206,000	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	72,252	801,109	SH		SOLE		801,109	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	93,778	240,000	SH		SOLE		240,000	0	0
VERVE THERAPEUTICS INC	COM	92539P101	45,253	962,826	SH		SOLE		962,826	0	0
VINCERX PHARMA INC	COM NEW	92731L106	12,941	800,295	SH		SOLE		800,295	0	0
WARBY PARKER INC	CL A COM	93403J106	34,483	650,000	SH		SOLE		650,000	0	0
WEST PHARMACEUTICAL SVSC INC	COM	955306105	12,736	30,000	SH		SOLE		30,000	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	8,910	583,100	SH		SOLE		583,100	0	0
ZAI LAB LTD	ADR	98887Q104	113,584	1,077,750	SH		SOLE		1,077,750	0	0