Document And Entity Information
Document And Entity Information - shares | 6 Months Ended | |
Jun. 30, 2018 | Aug. 01, 2018 | |
Document Information [Line Items] | ||
Document Type | 10-Q | |
Amendment Flag | false | |
Document Period End Date | Jun. 30, 2018 | |
Document Fiscal Year Focus | 2,018 | |
Document Fiscal Period Focus | Q2 | |
Entity Registrant Name | Celcuity Inc. | |
Entity Central Index Key | 1,603,454 | |
Current Fiscal Year End Date | --12-31 | |
Entity Filer Category | Smaller Reporting Company | |
Trading Symbol | CELC | |
Entity Common Stock, Shares Outstanding | 10,119,312 |
Condensed Balance Sheets
Condensed Balance Sheets - USD ($) | Jun. 30, 2018 | Dec. 31, 2017 |
Current Assets: | ||
Cash and cash equivalents | $ 3,172,782 | $ 2,639,789 |
Investments | 18,385,920 | 21,556,857 |
Restricted cash | 50,000 | 50,000 |
Deposits | 27,726 | 27,726 |
Prepaid assets | 154,002 | 209,708 |
Total current assets | 21,790,430 | 24,484,080 |
Property and equipment, net | 730,449 | 280,056 |
Long term investments | 6,948,606 | 7,205,374 |
Total Assets | 29,469,485 | 31,969,510 |
Current Liabilities: | ||
Accounts payable | 149,401 | 71,913 |
Capital lease obligations | 5,706 | 0 |
Accrued expenses | 807,783 | 506,140 |
Total current liabilities | 962,890 | 578,053 |
Capital lease obligations | 23,226 | 0 |
Total Liabilities | 986,116 | 578,053 |
Commitments and contingencies | ||
Stockholders' Equity: | ||
Preferred stock, $0.001 par value: 2,500,000 and 5,000,000 shares authorized as of June 30, 2018 and December 31, 2017, respectively; 0 shares issued and outstanding as of June 30, 2018 and December 31, 2017 | 0 | 0 |
Common stock, $0.001 par value: 25,000,000 and 45,000,000 shares authorized as of June 30, 2018 and December 31, 2017, respectively; 10,119,312 and 10,087,516 shares issued and outstanding as of June 30, 2018 and December 31, 2017, respectively | 10,119 | 10,087 |
Additional paid-in capital | 34,264,884 | 33,388,597 |
Accumulated deficit | (5,791,634) | (2,007,227) |
Total Stockholders' Equity | 28,483,369 | 31,391,457 |
Total Liabilities and Stockholders' Equity | $ 29,469,485 | $ 31,969,510 |
Condensed Balance Sheets _Paren
Condensed Balance Sheets [Parenthetical] - $ / shares | Jun. 30, 2018 | Dec. 31, 2017 |
Preferred Stock, Par or Stated Value Per Share | $ 0.001 | $ 0.001 |
Preferred Stock, Shares Authorized | 2,500,000 | 5,000,000 |
Preferred Stock, Shares Issued | 0 | 0 |
Preferred Stock, Shares Outstanding | 0 | 0 |
Common Stock, Par or Stated Value Per Share | $ 0.001 | $ 0.001 |
Common Stock, Shares Authorized | 25,000,000 | 45,000,000 |
Common Stock, Shares, Issued | 10,119,312 | 10,087,516 |
Common Stock, Shares, Outstanding | 10,119,312 | 10,087,516 |
Condensed Statements of Operati
Condensed Statements of Operations - USD ($) | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | |
Operating expenses: | ||||
Research and development | $ 1,546,537 | $ 1,303,886 | $ 3,092,205 | $ 2,212,629 |
General and administrative | 382,646 | 301,820 | 913,286 | 386,963 |
Total operating expenses | 1,929,183 | 1,605,706 | 4,005,491 | 2,599,592 |
Loss from operations | (1,929,183) | (1,605,706) | (4,005,491) | (2,599,592) |
Other income (expense) | ||||
Interest expense | 0 | (186,659) | 0 | (186,686) |
Interest income | 112,722 | 16,150 | 221,084 | 22,712 |
Other income (expense), net | 112,722 | (170,509) | 221,084 | (163,974) |
Net loss before income taxes | (1,816,461) | (1,776,215) | (3,784,407) | (2,763,566) |
Income tax benefits | 0 | 0 | 0 | 0 |
Net loss | $ (1,816,461) | $ (1,776,215) | $ (3,784,407) | $ (2,763,566) |
Net loss per share, basic and diluted | $ (0.18) | $ (0.28) | $ (0.37) | $ (0.43) |
Weighted average common shares outstanding, basic and diluted | 10,110,558 | 6,440,139 | 10,103,323 | 6,440,139 |
Condensed Statements of Cash Fl
Condensed Statements of Cash Flows - USD ($) | 6 Months Ended | |
Jun. 30, 2018 | Jun. 30, 2017 | |
Cash flows from operating activities: | ||
Net loss | $ (3,784,407) | $ (2,763,566) |
Adjustments to reconcile net loss to net cash used for operations: | ||
Depreciation | 89,704 | 45,449 |
Stock-based compensation | 612,764 | 422,816 |
Non-cash interest expense | 0 | 186,759 |
Non-cash interest income adjustment | 2,705 | 0 |
Changes in operating assets and liabilities: | ||
Prepaid assets and deposits | 55,706 | (156,120) |
Accounts payable | 12,604 | (34,771) |
Accrued expenses | 226,643 | 89,700 |
Net cash used for operating activities | (2,784,281) | (2,209,733) |
Cash flows from investing activities: | ||
Purchases of investments | (3,235,000) | 0 |
Proceeds from sale of investments | 6,660,000 | 0 |
Purchases of property and equipment | (372,282) | (165,851) |
Proceeds from sale of property and equipment | 1,000 | 0 |
Net cash provided by (used for) investing activities | 3,053,718 | (165,851) |
Cash flows from financing activities: | ||
Proceeds from sale of convertible promissory notes | 0 | 7,493,330 |
Payments for debt issuance costs | 0 | (40,961) |
Deferred transaction costs | 0 | (25,065) |
Proceeds from exercise of common stock warrants | 183,759 | 0 |
Proceeds from employee stock purchases | 79,797 | 0 |
Net cash provided by financing activities | 263,556 | 7,427,304 |
Net change in cash, cash equivalents, and restricted cash | 532,993 | 5,051,720 |
Cash, cash equivalents, and restricted cash: | ||
Beginning of period | 2,689,789 | 5,906,348 |
End of period | $ 3,222,782 | $ 10,958,068 |
Condensed Statements of Cash F6
Condensed Statements of Cash Flows (Additional Information) - USD ($) | 6 Months Ended | |
Jun. 30, 2018 | Jun. 30, 2017 | |
Cash and cash equivalents | $ 3,172,782 | $ 10,908,068 |
Restricted cash | 50,000 | 50,000 |
Total | 3,222,782 | 10,958,068 |
Supplemental disclosures of non-cash investing and financing activities: | ||
Property and equipment included in accounts payable | 64,883 | 0 |
Property and equipment funded by capital lease | 28,932 | 0 |
Leasehold improvements funded by landlord and related deferred rent included in accrued expenses | 75,000 | 0 |
Debt issuance costs netted against proceeds from sale of convertible promissory notes | 0 | 844,170 |
Debt discount related to investor and agent warrants (Note 11) | 0 | 1,063,715 |
Deferred transaction costs included in accounts payable and accrued expenses | $ 0 | $ 276,666 |
Organization
Organization | 6 Months Ended |
Jun. 30, 2018 | |
Organization, Consolidation and Presentation of Financial Statements [Abstract] | |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] | 1. Organization Nature of Business Celcuity Inc., a Delaware corporation (the “Company”), is a cellular analysis company that is discovering new cancer sub-types and commercializing diagnostic tests designed to significantly improve the response rates of cancer patients treated with targeted therapies. The Company’s proprietary CELx diagnostic platform is currently the only commercially ready technology the Company is aware of that uses a patient’s living tumor cells to evaluate the functional status of the cell signaling pathways associated with cancer. The CELx platform identifies the abnormal signaling activity driving a patient’s cancer and quantifies how effectively a targeted therapy can treat it. This enables physicians to select the therapeutic that precisely matches and inhibits a patient’s cellular dysfunction, which significantly increases the likelihood of a positive clinical outcome. The Company was co-founded in 2012 by Brian Sullivan and Lance Laing and is based in Minnesota. The Company has not generated any revenues to date. |
Summary of Significant Accounti
Summary of Significant Accounting Policies | 6 Months Ended |
Jun. 30, 2018 | |
Accounting Policies [Abstract] | |
Significant Accounting Policies [Text Block] | 2. Summary of Significant Accounting Policies Basis of Presentation The accompanying unaudited financial statements include the accounts of the Company and have been prepared in accordance with Article 10 of Regulation S-X promulgated by the Securities and Exchange Commission (“SEC”). Accordingly, as permitted by Article 10, the unaudited financial statements do not include all of the information required by accounting principles generally accepted in the United States (“U.S. GAAP”). The Balance Sheet at December 31, 2017 was derived from the audited financial statements at that date and does not include all the disclosures required by U.S. GAAP. In the opinion of management, all adjustments which are of a normal recurring nature and necessary for a fair presentation have been reflected in the financial statements. These unaudited condensed financial statements should be read in conjunction with the audited financial statements as of and for the year ended December 31, 2017 and the related footnotes thereto included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2017. Operating results for the three and six months ended June 30, 2018 are not necessarily indicative of the results to be expected during the remainder of the current year or for any future period. On September 15, 2017, in relation to preparing for its initial public offering (“IPO”), Celcuity LLC filed a certificate of conversion, whereby Celcuity LLC effected a corporate conversion from a Minnesota limited liability company to a Delaware corporation and changed its name to Celcuity Inc. Pursuant to the corporate conversion, units of membership interest in the limited liability company were converted into shares of common stock of the corporation at a conversion ratio of 40 units for one share of common stock. As a result of the corporate conversion, accumulated deficit was reduced to zero on the date of the corporate conversion, and the corresponding amount was credited to additional paid-in capital. The corporate conversion was approved by members holding a majority of our outstanding units, and in connection with such conversion, the Company filed a certificate of incorporation and adopted bylaws. The Company determined that the corporate conversion is equivalent to a change in the Company’s capital structure. As such, all references in the unaudited financial statements to the number of shares and per-share amounts of member units are now presented as common stock and have been retroactively restated to reflect the conversion. On September 22, 2017, the Company completed its IPO whereby it sold 2,760,000 shares of common stock at a public offering price of $9.50 per share. The aggregate net proceeds received by the Company from the offering were approximately $23.3 million, net of underwriting discounts and commissions of approximately $1.8 million and offering expenses of approximately $1.1 million. Upon the closing of the IPO, 10,082,050 shares of common stock were outstanding, which includes 881,911 shares of common stock as a result of the conversion of the Company’s Unsecured Convertible Promissory Notes (See Note 11). Shares of the Company’s common stock began trading on September 20, 2017 on The Nasdaq Capital Market under the symbol “CELC”. On May 11, 2018, the Company filed an amendment to its certificate of incorporation to decrease the number of authorized shares of common stock and preferred stock. Pursuant to the Company’s amended certificate of incorporation, the Company is authorized to issue up to 25,000,000 shares of common stock, $0.001 par value per share and 2,500,000 shares of preferred stock, $0.001 par value per share. Accounting Estimates Management uses estimates and assumptions in preparing these unaudited condensed financial statements in accordance with U.S. GAAP. Those estimates and assumptions affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities, and the reported revenues and expenses. Actual results could differ from those estimates. Significant items subject to such estimates and assumptions include the valuation of stock-based compensation and warrants issued to investors, a placement agent and an underwriter, and prepaid or accrued clinical trial costs. Cash, Cash Equivalents, and Restricted Cash The Company maintains its accounts primarily at one financial institution. At times throughout the year, the Company’s cash balances may exceed amounts insured by the Federal Deposit Insurance Corporation. At June 30, 2018 and December 31, 2017, the Company had $3,135,878 and $2,612,104, respectively, in money market funds and U.S. Treasury Bills that are considered cash equivalents. In connection with the corporate lease, the Company is required to maintain $50,000 of cash in a separate savings account. This balance is presented as restricted cash on the balance sheets. Investments The Company maintains its investments in certificates of deposit, U.S. governmental agency securities and U.S. treasury notes and has classified them as held-to-maturity at the time of purchase. Held-to-maturity securities are those securities in which the Company has the ability and intent to hold until maturity. Held-to maturity securities are recorded at amortized cost, adjusted for the amortization or accretion of premiums and discounts. Premiums and discounts are amortized or accreted over the life of the related held-to-maturity security using a straight-line method. At June 30, 2018 and December 31, 2017, the Company had $25,334,526 and $28,762,231, respectively, of investments. Property and Equipment Property and equipment are stated at cost. Depreciation is provided over estimated useful lives using the straight-line method. Maintenance and repairs are expensed as incurred; major improvements and betterments are capitalized. Estimated useful lives of property and equipment are as follows for the major classes of assets: Asset Description Estimated Lives Furniture and Equipment 4-5 Leasehold Improvements 2-3 Long-Lived Assets Long-lived assets, such as property and equipment, are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. If circumstances require a long-lived asset or asset group be tested for possible impairment, the Company first compares undiscounted cash flows expected to be generated by that asset or asset group to its carrying value. If the carrying value of the long-lived asset or asset group is not recoverable on an undiscounted cash flow basis, an impairment is recognized to the extent that the carrying value exceeds its fair value. Fair value is determined through various valuation techniques including discounted cash flow models, quoted market values, and third party independent appraisals, as considered necessary. Comprehensive Loss Comprehensive loss includes net loss as well as other changes in stockholders’ equity that result from transactions and economic events other than those with stockholders. For all periods presented, there was no difference between net loss and comprehensive loss. Risks and Uncertainties The Company is subject to risks common to companies in the development stage including, but not limited to, dependency on the clinical and commercial success of its diagnostic tests, ability to obtain regulatory approval of its diagnostic tests, the need for substantial additional financing to achieve its goals, uncertainty of broad adoption of its approved products, if any, by physicians and consumers, and significant competition. Fair Value of Financial Instruments The Company’s accounting for fair value measurements of assets and liabilities that are recognized or disclosed at fair value in the financial statements on a recurring or nonrecurring basis adheres to the Financial Accounting Standards Board (“FASB”) fair value hierarchy that prioritizes the inputs to valuation techniques used to measure fair value. The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to measurements involving significant unobservable inputs (Level 3 measurements). The three levels of the fair value hierarchy are as follows: Level 1 Inputs: Unadjusted quoted prices in active markets for identical assets or liabilities accessible to the Company at the measurement date. Level 2 Inputs: Other than quoted prices included in Level 1 inputs that are observable for the asset or liability, either directly or indirectly, for substantially the full term of the asset or liability. Level 3 Inputs: Unobservable inputs for the asset or liability used to measure fair value to the extent that observable inputs are not available, thereby allowing for situations in which there is little, if any, market activity for the asset or liability at measurement date. The level in the fair value hierarchy within which a fair measurement in its entirety falls is based on the lowest level input that is significant to the fair value measurement in its entirety. The carrying values of cash equivalents, restricted cash, accounts payable, accrued expenses and other financial working capital items approximate fair value at June 30, 2018 and December 31, 2017 due to the short maturity nature of these items. Income Taxes The Company accounts for income taxes using the asset and liability method, as required by the accounting standard for income taxes. Under this method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases, as well as net operating loss and tax credit carryforwards. Deferred taxes are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred taxes of a change in tax rates is recognized in results of operations in the period that includes the enactment date. The effects of any future changes in tax laws or rates have not been considered. The Company regularly reviews deferred tax assets to assess their potential realization and establish a valuation allowance for portions of such assets to reduce the carrying value if the Company does not consider it to be more likely than not that the deferred tax assets will be realized. The Company recognizes the impact of an uncertain tax position in its financial statements if, in management’s judgment, the position is more-likely-than-not sustainable upon audit based on the position’s technical merits. This involves the identification of potential uncertain tax positions, the evaluation of applicable tax laws and an assessment of whether a liability for an uncertain tax position is necessary. Stock-Based Compensation The Company’s stock-based compensation consists of common stock options and restricted stock issued to certain employees and nonemployees of the Company and the Company’s Employee Stock Purchase Plan. The Company recognizes compensation expense based on an estimated grant date fair value using the Black-Scholes option-pricing method. The Company has elected to account for forfeitures as they occur. Research and Development Research and development costs are expensed as incurred. Research and development costs amounted to $3,092,205 and $2,212,629 for the six months ended June 30, 2018 and 2017, respectively, and $1,546,537 and $1,303,886 for the three months ended June 30, 2018 and 2017, respectively. Clinical Trial Costs The Company records prepaid assets or accrued expenses for prepaid or estimated clinical trial costs conducted by third-party service providers, which include the conduct of preclinical studies and clinical trials. These costs are a significant component of the Company’s research and development expenses. The Company accrues for these costs based on factors such as estimates of the work completed and in accordance with agreements established with its third-party service providers under the service agreements. The Company makes significant judgments and estimates in determining the accrued liabilities balance in each reporting period. As actual costs become known, the Company adjusts its prepaid assets or accrued expenses. The Company has not experienced any material differences between accrued costs and actual costs incurred. However, the status and timing of actual services performed, number of patients enrolled and the rate of patient enrollments may vary from the Company’s estimates, resulting in an adjustment to expense in future periods. Changes in these estimates that result in material changes to the Company’s prepaid assets or accrued expenses could materially affect the Company’s results of operations. Application of New or Revised Accounting Standards Pursuant to the Jumpstart Our Business Startups Act of 2012 (the “JOBS Act”), a company constituting an “emerging growth company” is, among other things, entitled to rely upon certain reduced reporting requirements. The Company is an emerging growth company, but has irrevocably elected not to take advantage of the extended transition period afforded by the JOBS Act for the implementation of new or revised accounting standards. As a result, the Company will comply with new or revised accounting standards on the relevant dates on which adoption of such standards is required for public companies that are not emerging growth companies. Recently Issued Accounting Pronouncements In February 2016, the FASB issued ASU No. 2016-02, Leases (Topic 842), which provides guidance for accounting for leases. The new guidance requires companies to recognize the assets and liabilities for the rights and obligations created by leased assets, initially measured at the present value of the lease payments. The accounting guidance for lessors is largely unchanged. The ASU is effective for annual and interim periods beginning after December 15, 2018 with early adoption permitted. It is to be adopted using a modified retrospective approach. The Company is currently evaluating the impact that the adoption of this guidance will have on the Company’s financial statements. Recently Adopted Accounting Pronouncements In November 2016, the FASB issued Accounting Standards Update (ASU) No. 2016-18, Restricted Cash Statement of Cash Flows (Topic 230) of the Accounting Standards Codification. The new guidance requires amounts generally described as restricted cash and restricted cash equivalents to be included with cash and cash equivalents when reconciling the beginning-of-period and end-of-period total amounts shown on the statement of cash flows. The Company adopted this standard as of January 1, 2018 and applied it retrospectively. In June 2018, the FASB issued Accounting Standards Update (ASU) No. 2018-07, Improvements to Nonemployee Share-Based Payment Accounting |
Net Loss Per Common Share
Net Loss Per Common Share | 6 Months Ended |
Jun. 30, 2018 | |
Earnings Per Share [Abstract] | |
Earnings Per Share [Text Block] | 3. Net Loss Per Common Share Basic and diluted net loss per common share is determined by dividing net loss attributable to common stockholders by the weighted-average common shares outstanding during the period. For all periods presented, the common shares underlying the options and warrants have been excluded from the calculation because their effect would be anti-dilutive. Therefore, the weighted-average shares outstanding used to calculate both basic and diluted loss per common shares are the same. For the three and six months ended June 30, 2018 and 2017, potentially dilutive securities excluded from the computations of diluted weighted-average shares outstanding were options to purchase 522,755 and 442,685 shares of common stock, respectively, warrants to purchase 353,980 and 103,864 shares of common stock, respectively, and 2,571 and 0 shares of restricted common stock, respectively. |
Investments
Investments | 6 Months Ended |
Jun. 30, 2018 | |
Investments, Debt and Equity Securities [Abstract] | |
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] | 4. Investments The following tables summarizes the Company’s held-to-maturity investment securities at amortized cost as of June 30, 2018 and December 31, 2017: June 30, 2018 Amortized Cost, Gross Gross Estimated Fair Short-term investments: Certificates of Deposit $ 10,609,185 $ - $ 21,912 $ 10,587,273 Governmental Agency Securities 5,285,044 - 15,359 5,269,685 U.S. Treasury Notes 2,491,691 - 2,849 2,488,842 Total $ 18,385,920 $ - $ 40,120 $ 18,345,800 Amortized Cost, Gross Gross Estimated Fair Long-term investments: Certificates of Deposit $ 3,920,000 $ - $ 43,819 $ 3,876,181 Governmental Agency Securities 3,028,606 - $ 29,974 2,998,632 Total $ 6,948,606 $ - $ 73,793 $ 6,874,813 December 31, 2017 Amortized Cost, Gross Gross Estimated Fair Short-term investments: Certificates of Deposit $ 14,001,237 $ - $ 20,146 $ 13,981,091 Governmental Agency Securities 5,945,314 - 18,101 5,927,213 U.S. Treasury Notes 1,610,306 - 633 1,609,673 Total $ 21,556,857 $ - $ 38,880 $ 21,517,977 Amortized Cost, Gross Gross Estimated Fair Long-term investments: Certificates of Deposit $ 4,165,000 $ - $ 21,481 $ 4,143,519 Governmental Agency Securities 3,040,374 - 14,907 3,025,467 Total $ 7,205,374 $ - $ 36,388 $ 7,168,986 The Company’s held-to-maturity investments of $18,385,920 and $6,948,606 will mature in 2018 and 2019, respectively. |
Prepaid Assets
Prepaid Assets | 6 Months Ended |
Jun. 30, 2018 | |
Prepaid Expense, Current [Abstract] | |
Disclosure Of Prepaid Assets [Text Block] | 5. Prepaid Assets Prepaid assets consisted of the following: June 30, December 31, 2018 2017 Current: Directors & officers insurance $ 47,917 $ 162,914 Prepaid rent 21,490 21,673 Other 84,595 25,121 Total $ 154,002 $ 209,708 |
Property and Equipment
Property and Equipment | 6 Months Ended |
Jun. 30, 2018 | |
Property, Plant and Equipment [Abstract] | |
Property, Plant and Equipment Disclosure [Text Block] | 6. Property and Equipment Property and equipment consisted of the following: June 30, December 31, 2018 2017 Leasehold improvements $ 277,836 $ 22,307 Furniture and equipment 800,177 517,868 1,078,013 540,175 Less: Accumulated depreciation (347,564 ) (260,119 ) Total $ 730,449 $ 280,056 Depreciation expense was $89,704 and $45,449 for the six months ended June 30, 2018 and 2017, respectively, and $49,966 and $25,722 for the three months ended June 30, 2018 and 2017, respectively. |
Accrued Expenses
Accrued Expenses | 6 Months Ended |
Jun. 30, 2018 | |
Payables and Accruals [Abstract] | |
Accounts Payable and Accrued Liabilities Disclosure [Text Block] | 7. Accrued Expenses Accrued expenses consisted of the following: June 30, December 31, 2018 2017 Accrued bonuses $ 544,804 $ 389,802 Deferred rent 74,652 - Accrued payroll 66,324 61,829 Other 122,003 54,509 Total $ 807,783 $ 506,140 |
Commitments
Commitments | 6 Months Ended |
Jun. 30, 2018 | |
Commitments and Contingencies Disclosure [Abstract] | |
Commitments Disclosure [Text Block] | 8. Commitments Operating Leases The Company leases its corporate space in Minneapolis, Minnesota. At June 30, 2018, the Company had the following minimum commitments for payment of rentals which at inception had a non-cancellable term of more than one year: Amount 2018 $ 77,419 2019 188,850 2020 193,338 2021 64,940 Total $ 524,547 Rent expense for operating leases was $43,198 and $25,077 for the six months ended June 30, 2018 and 2017, respectively, and $30,009 and $12,668 for the three months ended June 30, 2018 and 2017, respectively. In connection with the corporate lease, the Company is required to maintain a $50,000 standby letter of credit. The standby letter of credit expires on July 31, 2018. In September 2017, the Company entered into a non-cancelable operating lease agreement for building space to accommodate expansion in research and development and general corporate office needs. The new lease commenced, and the Company moved to the facility in May 2018, in conjunction with the termination of the existing lease. The new lease contains provisions for future rent increases and leasehold improvement allowances. Rent expense is recorded on a straight-line basis over the lease term. The net difference of rent expense versus the actual cash paid is recorded as deferred rent. Additionally, the leasehold improvement allowances are deferred and recorded as a reduction of rental expense over the lease term using the straight-line method. Deferred rent is reflected in accrued expenses in the unaudited condensed financial statements. The new lease agreement extends through April 2021 and provides for monthly rent, real estate taxes and operating expenses. Clinical Research Study In May 2017, the Company entered into an agreement with a clinical research organization to conduct a clinical research study. The Company made a payment of $300,000 in June 2017 and $50,000 in November 2017, January 2018 and April 2018 and is obligated to make future payments of $100,000 and $50,000 in 2018 and 2019, respectively. Additional payments will be due as certain milestones are met. The maximum amount of these additional payments is estimated to be approximately $2,040,000 over the course of the agreement. Capital Leases In May 2018, the Company entered into a non-cancelable capital lease agreement for office equipment with a five-year term. The underlying assets are included in furniture and equipment. Assets recorded as property and equipment under capital leases and the accumulated depreciation thereon as of June 30, 2018 were as follows: June 30, 2018 Furniture and equipment $ 28,932 Less: Accumulated depreciation (482 ) Net book value of property and equipment under capital lease $ 28,450 As of June 30, 2018, future minimum lease payments under capital leases were as follows: Amount 2018 $ 4,232 2019 7,255 2020 7,255 2021 7,255 2022 7,255 2023 3,022 Total minimum capital lease payments 36,274 Less amount representing interest 512 Less amount representing services 6,830 Present value of net minimum capital lease payments $ 28,932 |
Stockholders' Equity
Stockholders' Equity | 6 Months Ended |
Jun. 30, 2018 | |
Equity [Abstract] | |
Stockholders' Equity Note Disclosure [Text Block] | 9. Stockholders’ Equity On September 15, 2017, in connection with its IPO, Celcuity LLC filed a certificate of conversion, whereby Celcuity LLC effected a corporate conversion from a Minnesota limited liability company to a Delaware corporation and changed its name to Celcuity Inc. Pursuant to the conversion, units of membership interest in the limited liability company were converted into shares of common stock of the corporation at a conversion ratio of 40 units for one share of common stock. The Company had 257,604,208 member units issued and outstanding as of September 15, 2017. After giving effect to the corporate conversion, the number of common shares outstanding as of such date is 6,440,139. As a result of the corporate conversion, accumulated deficit was reduced to zero on the date of the corporate conversion, and the corresponding amount was credited to additional paid-in capital. The corporate conversion was approved by members holding a majority of our outstanding units, and in connection with such conversion, the Company filed a certificate of incorporation and adopted bylaws. All references in the unaudited financial statements to the number of shares and per-share amounts of common stock have been retroactively restated to reflect the conversion. On September 22, 2017, the Company completed its IPO whereby it sold 2,760,000 shares of common stock at a public offering price of $9.50 per share. The aggregate net proceeds received by the Company from the offering were approximately $23.3 million, net of underwriting commissions of approximately $1.8 million and offering expenses of approximately $1.1 million. Upon the closing of the IPO, 10,082,050 shares of common stock were outstanding, which includes 881,911 shares of common stock issued as a result of the conversion of the Company’s Convertible Notes (See Note 11). Shares of the Company’s common stock began trading on September 20, 2017 on The Nasdaq Capital Market under the symbol “CELC”. On May 11, 2018, the Company filed an amendment to its certificate of incorporation with the Secretary of State of the State of Delaware to decrease the number of authorized shares of our common stock and preferred stock. Pursuant to the Company’s amended certificate of incorporation, the Company is authorized to issue up to 25,000,000 shares of common stock, $0.001 par value per share and 2,500,000 shares of preferred stock, $0.001 par value per share. At June 30, 2018 and December 31, 2017, the Company had common stock shares outstanding of 10,119,312 and 10,087,516, respectively. Warrants In connection with the 2016 private placement unit offering, the Company issued ten-year warrants to the placement agent of the private placement. The warrants allow the agent to purchase up to 55,249 common shares at $7.56 per share. The warrants are immediately exercisable and expire on January 14, 2026 and May 2, 2026. These warrants are equity classified and the fair value of $330,607 is reflected as additional paid-in capital. In connection with the private offering of convertible notes (Note 11), the Company issued ten-year warrants to purchase 48,615 common shares at a price of $8.42 per share to the placement agent. In addition, the Company granted the convertible notes investors the right to receive a seven-year warrant to purchase 131,675 common shares at an exercise price that is equal to the conversion price of the notes (Note 11). With the completion of the IPO on September 22, 2017, these warrants were issued. In connection with the IPO, the Company issued a five-year warrant to the underwriter. The warrant allows the underwriter to purchase up to 138,000 common shares at $10.45 per share. This warrant is immediately exercisable and expires on September 19, 2022. This warrant is equity classified and the fair value was $784,111 at the IPO offering date. At June 30, 2018 and December 31, 2017, the Company had warrants to purchase 353,980 and 373,323 common shares outstanding, respectively, at a weighted average exercise price of $9.42. A total of 19,343 and 0 warrants were exercised in the six months ended June 30, 2018 and 2017, respectively, and 0 warrants were exercised in the three months ended June 30, 2018 and 2017. |
Stock-Based Compensation
Stock-Based Compensation | 6 Months Ended |
Jun. 30, 2018 | |
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] | |
Disclosure of Compensation Related Costs, Share-based Payments [Text Block] | 10. Stock-Based Compensation 2012 Equity Incentive Plan The 2012 Equity Incentive Plan, as amended, was adopted by the Company’s board and approved by the members of the Company on August 10, 2012. The Company reserved a maximum of 625,000 common shares available for issuance under the 2012 Equity Incentive Plan. The 2012 Equity Incentive Plan provides for share options, restricted share awards, performance share awards or share bonuses. The exercise price of each share option granted under the 2012 Equity Incentive Plan is not less than one hundred percent (100%) of the fair market value of one share on the date of grant. The maximum permitted term of options granted under the 2012 Equity Incentive Plan is ten years. The Company’s board has administered the plan and determined the provisions of incentive awards, including eligible recipients, number of shares subject to an incentive award, exercise price, vesting schedule, duration of an incentive award and other restrictions an incentive award may be subject to. The 2012 Equity Incentive Plan was fixed on September 6, 2017 and any new awards will be issued under the terms of the 2017 Stock Incentive Plan. 2017 Stock Incentive Plan The 2017 Stock Incentive Plan, or the 2017 Plan, was adopted by the Company’s board on September 6, 2017, became effective following the corporate conversion which took place on September 15, 2017, and was approved by stockholders at the Company’s annual stockholder meeting on May 10, 2018. The Company reserved a maximum of 750,000 common shares available for issuance under the 2017 Plan. The number of shares reserved for issuance under the 2017 Plan will increase automatically on January 1, 2019 and each subsequent anniversary through January 1, 2027 by the number of shares equal to 1.0% of the aggregate number of outstanding shares of the Company’s common stock as of the immediately preceding December 31. However, the Company’s board may reduce the amount of the increase in any particular year. The maximum permitted term of options granted under the 2017 Plan is ten years. The 2017 Plan provides for share options, restricted stock awards, stock appreciation rights, restricted stock units, performance awards and stock bonuses. The exercise price of each share option granted under the 2017 Plan is not less than one hundred percent (100%) of the fair market. The 2017 Plan will generally be administered by the compensation committee of the Company’s board of directors and has the authority to interpret the plan, grant awards and make all other determinations necessary for the administration of the plan. The Black-Scholes option-pricing model was used to estimate the fair value of equity-based awards with the following weighted-average assumptions for the period ending June 30: 2018 2017 Risk-free interest rate 2.52 - 2.97% 2.00 Expected volatility 76.0% 75.0% Expected life (years) 6.25 to 10.00 6.25 to 10.00 Expected dividend yield 0% 0% The inputs for the Black-Scholes valuation model require management’s significant assumptions. Prior to the Company’s IPO, the common share price was determined by the Company’s board based on recent prices of common shares sold in private offerings prior to the IPO. Subsequent to the IPO, the common share price was determined by using the quoted price on the grant date. The risk-free interest rates were based on the rate for U.S. Treasury securities at the date of grant with maturity dates approximately equal to the expected life at the grant date. The expected life was based on the simplified method in accordance with the SEC Staff Accounting Bulletin Nos. 107 and 110. The expected volatility was estimated based on historical volatility information of peer companies that are publicly available. All assumptions used to calculate the grant date fair value of nonemployee options are generally consistent with the assumptions used for options granted to employees, except the expected life is equal to the contractual term. In the event the Company terminates any of its consulting agreements, the unvested options underlying the agreements would also be cancelled. Unvested nonemployee options were marked-to-market as of April 1, 2018, the date that the Company adopted the newly issued Accounting Standard, (ASU) No. 2018-17. The following table summarizes the activity for all stock options outstanding for the six months ended June 30 under the Plan: 2018 2017 Shares Weighted Average Exercise Price Shares Weighted Average Exercise Price Options outstanding at beginning of year 501,603 $ 7.58 302,088 $ 5.91 Granted 21,152 18.93 148,150 8.38 Forfeited - - (7,553 ) 3.60 Balance at June 30 522,755 $ 8.04 442,685 $ 6.78 Options exercisable at June 30: 262,393 $ 6.72 166,119 $ 5.46 Weighted Average Grant Date Fair Value for Options Granted During the period: $ 14.02 $ 5.29 The following table summarizes additional information about stock options outstanding and exercisable at June 30, 2018 under the Plan: Options Outstanding Options Exercisable Options Weighted Weighted Aggregate Options Weighted Aggregate 522,755 8.14 $ 8.04 $ 8,771,626 262,393 $ 6.72 $ 4,748,003 The Company recognized stock-based compensation expense for stock options of $501,158 and $422,816 for the six months ended June 30, 2018 and 2017, respectively, and $235,060 and $326,548 for the three months ended June 30, 2018 and 2017, respectively. A restricted stock award of 2,571 and 5,250 shares was granted to a member of the board of directors in 2018 and 2017, respectively. The Company has 2,571 and 0 restricted shares outstanding as of June 30, 2018 and 2017, respectively, and 5,250 and 0 shares vested as of June 30, 2018 and 2017, respectively. The Company recognized stock-based compensation expense for the restricted stock of $64,719 and $0 for the six months ended June 30, 2018 and 2017, respectively, and $22,431 and $0 for the three months ended June 30, 2018 and 2017, respectively. The total remaining shares available for grant under the 2017 plan is 664,297. Total unrecognized compensation cost related to stock options and restricted stock is estimated to be recognized as follows: 2018 $ 394,516 2019 515,020 2020 336,530 2021 153,773 2022 10,905 Total estimated compensation cost to be recognized $ 1,410,744 2017 Employee Stock Purchase Plan The Company’s employee stock purchase plan, or ESPP, was adopted by the Company’s board on September 6, 2017, and approved by stockholders at the Company’s annual stockholder meeting on May 10, 2018. The Company has reserved a total of 100,000 shares for issuance. The number of shares authorized and reserved for issuance under the ESPP will be automatically increased on the first day of each of the Company’s fiscal years beginning in 2019 by the number of shares equal to 0.5% of the total outstanding number of shares of common stock. However, the Company’s board may reduce the amount of the increase in any particular year. The ESPP provides participating employees with an opportunity to purchase shares of the Company’s common stock at a discount through payroll deductions. The plan is available to all employees unless they are employed for less than 20 hours per week or own 5% or more of the total combined voting power or value of the Company’s common stock. The plan is administered using overlapping 24 month offering periods, referred to as an Offering Period. Each Offering Period has four six-month purchase periods. A new Offering Period and purchase period begin every six months on May 1 and November 1 of each year. Participating employees may purchase common stock, on a voluntary after tax-basis, at a price equal to 85% of the fair market value of a share of common stock on either the offering date or the purchase date, whichever is lower. If the purchase date has a lower price, the employee will automatically be placed in the Offering Period beginning immediately after the purchase date. The Company recognized stock-based compensation expense of $46,887 and $0 for the six months ended June 30, 2018 and 2017, respectively, and $18,793 and $0 for the three months ended June 30, 2018 and 2017, respectively. The Company recognized total stock-based compensation, as follows for the three months and six months ended June 30: Three Months Ended Six Months Ended June 30, June 30, 2018 2017 2018 2017 Stock-based compensation expense in operating expenses: Research and development $ 175,864 $ 197,921 $ 337,535 $ 294,189 General and administrative 100,420 128,627 275,229 128,627 Total $ 276,284 $ 326,548 $ 612,764 $ 422,816 |
Unsecured Convertible Promissor
Unsecured Convertible Promissory Notes | 6 Months Ended |
Jun. 30, 2018 | |
Debt Disclosure [Abstract] | |
Debt Disclosure [Text Block] | 11. Unsecured Convertible Promissory Notes In April and May of 2017, the Company issued to certain accredited investors convertible notes in the original principal amount of $5,750,000 and $2,587,500, respectively, for total principal of $8,337,500 (the “Convertible Notes”). The Convertible Notes accrued interest at a rate of 1.25% per annum from date of issuance until December 31, 2018 on a non-compounding basis. All principal and interest was due on December 31, 2018. The IPO was considered a qualified financing, therefore the outstanding principal balance and all accrued interest under the Convertible Notes automatically converted into 881,911 shares of common stock pursuant to the terms of such notes. The conversion price of the Convertible Notes was equal to the price at which the equity securities were sold in the IPO, which was $9.50 per share. In connection with the issuance of the Convertible Notes, the Company granted those investors the right to receive a seven-year warrant to purchase 131,675 common shares at an exercise price that is equal to the conversion price of the Convertible Notes. The gross proceeds of $8,337,500 was allocated $7,560,783 and $776,717 to the Convertible Notes and warrants, respectively, based on their relative fair value. The relative fair value of the warrants of $776,717 was recorded as debt discount and credited to additional paid-in capital. The resulting debt discount was amortized to interest expense using the effective interest method over the term of the Convertible Notes until converted. Cedar Point Capital, LLC (“Cedar”) served as the Company’s placement agent in connection with the placement of the Convertible Notes and earned a commission of approximately 10% of the original principal balance of such notes. Debt financing costs in the aggregate of $885,131 (not including the agent warrant discussed below), comprised primarily of the commission earned by Cedar, were amortized to interest expense using the effective interest method over the term of the Convertible Notes until converted. In addition to the commission earned by Cedar, the Company issued an agent’s ten-year warrant to purchase 48,615 common shares. The exercise price was $8.42 per share. The fair value of the agent’s warrant was $286,999 and is considered additional debt discount and was credited to additional paid-in capital. During the period beginning on January 1, 2017 and ending on September 22, 2017 (the date of the IPO closing), the Company amortized $411,375 of debt discount and financing costs to interest expense for these Convertible Notes. |
Income Taxes
Income Taxes | 6 Months Ended |
Jun. 30, 2018 | |
Income Tax Disclosure [Abstract] | |
Income Tax Disclosure [Text Block] | 12. Income Taxes The Company has not recorded an income tax benefit for the six months and three months ended June 30, 2018 and 2017 due to net losses and recognition of a full valuation allowance. |
Summary of Significant Accoun19
Summary of Significant Accounting Policies (Policies) | 6 Months Ended |
Jun. 30, 2018 | |
Accounting Policies [Abstract] | |
Basis of Accounting, Policy [Policy Text Block] | Basis of Presentation The accompanying unaudited financial statements include the accounts of the Company and have been prepared in accordance with Article 10 of Regulation S-X promulgated by the Securities and Exchange Commission (“SEC”). Accordingly, as permitted by Article 10, the unaudited financial statements do not include all of the information required by accounting principles generally accepted in the United States (“U.S. GAAP”). The Balance Sheet at December 31, 2017 was derived from the audited financial statements at that date and does not include all the disclosures required by U.S. GAAP. In the opinion of management, all adjustments which are of a normal recurring nature and necessary for a fair presentation have been reflected in the financial statements. These unaudited condensed financial statements should be read in conjunction with the audited financial statements as of and for the year ended December 31, 2017 and the related footnotes thereto included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2017. Operating results for the three and six months ended June 30, 2018 are not necessarily indicative of the results to be expected during the remainder of the current year or for any future period. On September 15, 2017, in relation to preparing for its initial public offering (“IPO”), Celcuity LLC filed a certificate of conversion, whereby Celcuity LLC effected a corporate conversion from a Minnesota limited liability company to a Delaware corporation and changed its name to Celcuity Inc. Pursuant to the corporate conversion, units of membership interest in the limited liability company were converted into shares of common stock of the corporation at a conversion ratio of 40 units for one share of common stock. As a result of the corporate conversion, accumulated deficit was reduced to zero on the date of the corporate conversion, and the corresponding amount was credited to additional paid-in capital. The corporate conversion was approved by members holding a majority of our outstanding units, and in connection with such conversion, the Company filed a certificate of incorporation and adopted bylaws. The Company determined that the corporate conversion is equivalent to a change in the Company’s capital structure. As such, all references in the unaudited financial statements to the number of shares and per-share amounts of member units are now presented as common stock and have been retroactively restated to reflect the conversion. On September 22, 2017, the Company completed its IPO whereby it sold 2,760,000 shares of common stock at a public offering price of $9.50 per share. The aggregate net proceeds received by the Company from the offering were approximately $23.3 million, net of underwriting discounts and commissions of approximately $1.8 million and offering expenses of approximately $1.1 million. Upon the closing of the IPO, 10,082,050 shares of common stock were outstanding, which includes 881,911 shares of common stock as a result of the conversion of the Company’s Unsecured Convertible Promissory Notes (See Note 11). Shares of the Company’s common stock began trading on September 20, 2017 on The Nasdaq Capital Market under the symbol “CELC”. On May 11, 2018, the Company filed an amendment to its certificate of incorporation to decrease the number of authorized shares of common stock and preferred stock. Pursuant to the Company’s amended certificate of incorporation, the Company is authorized to issue up to 25,000,000 shares of common stock, $0.001 par value per share and 2,500,000 shares of preferred stock, $0.001 par value per share. |
Use of Estimates, Policy [Policy Text Block] | Accounting Estimates Management uses estimates and assumptions in preparing these unaudited condensed financial statements in accordance with U.S. GAAP. Those estimates and assumptions affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities, and the reported revenues and expenses. Actual results could differ from those estimates. Significant items subject to such estimates and assumptions include the valuation of stock-based compensation and warrants issued to investors, a placement agent and an underwriter, and prepaid or accrued clinical trial costs. |
Cash and Cash Equivalents, Policy [Policy Text Block] | Cash, Cash Equivalents, and Restricted Cash The Company maintains its accounts primarily at one financial institution. At times throughout the year, the Company’s cash balances may exceed amounts insured by the Federal Deposit Insurance Corporation. At June 30, 2018 and December 31, 2017, the Company had $3,135,878 and $2,612,104, respectively, in money market funds and U.S. Treasury Bills that are considered cash equivalents. In connection with the corporate lease, the Company is required to maintain $50,000 of cash in a separate savings account. This balance is presented as restricted cash on the balance sheets. |
Investment, Policy [Policy Text Block] | Investments The Company maintains its investments in certificates of deposit, U.S. governmental agency securities and U.S. treasury notes and has classified them as held-to-maturity at the time of purchase. Held-to-maturity securities are those securities in which the Company has the ability and intent to hold until maturity. Held-to maturity securities are recorded at amortized cost, adjusted for the amortization or accretion of premiums and discounts. Premiums and discounts are amortized or accreted over the life of the related held-to-maturity security using a straight-line method. At June 30, 2018 and December 31, 2017, the Company had $25,334,526 and $28,762,231, respectively, of investments. |
Property, Plant and Equipment, Policy [Policy Text Block] | Property and Equipment Property and equipment are stated at cost. Depreciation is provided over estimated useful lives using the straight-line method. Maintenance and repairs are expensed as incurred; major improvements and betterments are capitalized. Estimated useful lives of property and equipment are as follows for the major classes of assets: Asset Description Estimated Lives Furniture and Equipment 4-5 Leasehold Improvements 2-3 |
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block] | Long-Lived Assets Long-lived assets, such as property and equipment, are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. If circumstances require a long-lived asset or asset group be tested for possible impairment, the Company first compares undiscounted cash flows expected to be generated by that asset or asset group to its carrying value. If the carrying value of the long-lived asset or asset group is not recoverable on an undiscounted cash flow basis, an impairment is recognized to the extent that the carrying value exceeds its fair value. Fair value is determined through various valuation techniques including discounted cash flow models, quoted market values, and third party independent appraisals, as considered necessary. |
Comprehensive Income, Policy [Policy Text Block] | Comprehensive Loss Comprehensive loss includes net loss as well as other changes in stockholders’ equity that result from transactions and economic events other than those with stockholders. For all periods presented, there was no difference between net loss and comprehensive loss. |
Concentration Risk, Credit Risk, Policy [Policy Text Block] | Risks and Uncertainties The Company is subject to risks common to companies in the development stage including, but not limited to, dependency on the clinical and commercial success of its diagnostic tests, ability to obtain regulatory approval of its diagnostic tests, the need for substantial additional financing to achieve its goals, uncertainty of broad adoption of its approved products, if any, by physicians and consumers, and significant competition. |
Fair Value of Financial Instruments, Policy [Policy Text Block] | Fair Value of Financial Instruments The Company’s accounting for fair value measurements of assets and liabilities that are recognized or disclosed at fair value in the financial statements on a recurring or nonrecurring basis adheres to the Financial Accounting Standards Board (“FASB”) fair value hierarchy that prioritizes the inputs to valuation techniques used to measure fair value. The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to measurements involving significant unobservable inputs (Level 3 measurements). The three levels of the fair value hierarchy are as follows: Level 1 Inputs: Unadjusted quoted prices in active markets for identical assets or liabilities accessible to the Company at the measurement date. Level 2 Inputs: Other than quoted prices included in Level 1 inputs that are observable for the asset or liability, either directly or indirectly, for substantially the full term of the asset or liability. Level 3 Inputs: Unobservable inputs for the asset or liability used to measure fair value to the extent that observable inputs are not available, thereby allowing for situations in which there is little, if any, market activity for the asset or liability at measurement date. The level in the fair value hierarchy within which a fair measurement in its entirety falls is based on the lowest level input that is significant to the fair value measurement in its entirety. The carrying values of cash equivalents, restricted cash, accounts payable, accrued expenses and other financial working capital items approximate fair value at June 30, 2018 and December 31, 2017 due to the short maturity nature of these items. |
Income Tax, Policy [Policy Text Block] | Income Taxes The Company accounts for income taxes using the asset and liability method, as required by the accounting standard for income taxes. Under this method, deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases, as well as net operating loss and tax credit carryforwards. Deferred taxes are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred taxes of a change in tax rates is recognized in results of operations in the period that includes the enactment date. The effects of any future changes in tax laws or rates have not been considered. The Company regularly reviews deferred tax assets to assess their potential realization and establish a valuation allowance for portions of such assets to reduce the carrying value if the Company does not consider it to be more likely than not that the deferred tax assets will be realized. The Company recognizes the impact of an uncertain tax position in its financial statements if, in management’s judgment, the position is more-likely-than-not sustainable upon audit based on the position’s technical merits. This involves the identification of potential uncertain tax positions, the evaluation of applicable tax laws and an assessment of whether a liability for an uncertain tax position is necessary. |
Share-based Compensation, Option and Incentive Plans Policy [Policy Text Block] | Stock-Based Compensation The Company’s stock-based compensation consists of common stock options and restricted stock issued to certain employees and nonemployees of the Company and the Company’s Employee Stock Purchase Plan. The Company recognizes compensation expense based on an estimated grant date fair value using the Black-Scholes option-pricing method. The Company has elected to account for forfeitures as they occur. |
Research and Development Expense, Policy [Policy Text Block] | Research and Development Research and development costs are expensed as incurred. Research and development costs amounted to $3,092,205 and $2,212,629 for the six months ended June 30, 2018 and 2017, respectively, and $1,546,537 and $1,303,886 for the three months ended June 30, 2018 and 2017, respectively. Clinical Trial Costs The Company records prepaid assets or accrued expenses for prepaid or estimated clinical trial costs conducted by third-party service providers, which include the conduct of preclinical studies and clinical trials. These costs are a significant component of the Company’s research and development expenses. The Company accrues for these costs based on factors such as estimates of the work completed and in accordance with agreements established with its third-party service providers under the service agreements. The Company makes significant judgments and estimates in determining the accrued liabilities balance in each reporting period. As actual costs become known, the Company adjusts its prepaid assets or accrued expenses. The Company has not experienced any material differences between accrued costs and actual costs incurred. However, the status and timing of actual services performed, number of patients enrolled and the rate of patient enrollments may vary from the Company’s estimates, resulting in an adjustment to expense in future periods. Changes in these estimates that result in material changes to the Company’s prepaid assets or accrued expenses could materially affect the Company’s results of operations. |
Application of New or Revised Accounting Standards [Policy Text Block] | Application of New or Revised Accounting Standards Pursuant to the Jumpstart Our Business Startups Act of 2012 (the “JOBS Act”), a company constituting an “emerging growth company” is, among other things, entitled to rely upon certain reduced reporting requirements. The Company is an emerging growth company, but has irrevocably elected not to take advantage of the extended transition period afforded by the JOBS Act for the implementation of new or revised accounting standards. As a result, the Company will comply with new or revised accounting standards on the relevant dates on which adoption of such standards is required for public companies that are not emerging growth companies. |
New Accounting Pronouncements, Policy [Policy Text Block] | Recently Issued Accounting Pronouncements In February 2016, the FASB issued ASU No. 2016-02, Leases (Topic 842), which provides guidance for accounting for leases. The new guidance requires companies to recognize the assets and liabilities for the rights and obligations created by leased assets, initially measured at the present value of the lease payments. The accounting guidance for lessors is largely unchanged. The ASU is effective for annual and interim periods beginning after December 15, 2018 with early adoption permitted. It is to be adopted using a modified retrospective approach. The Company is currently evaluating the impact that the adoption of this guidance will have on the Company’s financial statements. Recently Adopted Accounting Pronouncements In November 2016, the FASB issued Accounting Standards Update (ASU) No. 2016-18, Restricted Cash Statement of Cash Flows (Topic 230) of the Accounting Standards Codification. The new guidance requires amounts generally described as restricted cash and restricted cash equivalents to be included with cash and cash equivalents when reconciling the beginning-of-period and end-of-period total amounts shown on the statement of cash flows. The Company adopted this standard as of January 1, 2018 and applied it retrospectively. In June 2018, the FASB issued Accounting Standards Update (ASU) No. 2018-07, Improvements to Nonemployee Share-Based Payment Accounting |
Summary of Significant Accoun20
Summary of Significant Accounting Policies (Tables) | 6 Months Ended |
Jun. 30, 2018 | |
Accounting Policies [Abstract] | |
Schedule Of Estimated Useful Lives Of Property Plant And Equipment [Table Text Block] | Estimated useful lives of property and equipment are as follows for the major classes of assets: Asset Description Estimated Lives Furniture and Equipment 4-5 Leasehold Improvements 2-3 |
Investments (Tables)
Investments (Tables) | 6 Months Ended |
Jun. 30, 2018 | |
Investments, Debt and Equity Securities [Abstract] | |
Held-to-maturity Securities [Table Text Block] | The following tables summarizes the Company’s held-to-maturity investment securities at amortized cost as of June 30, 2018 and December 31, 2017: June 30, 2018 Amortized Cost, Gross Gross Estimated Fair Short-term investments: Certificates of Deposit $ 10,609,185 $ - $ 21,912 $ 10,587,273 Governmental Agency Securities 5,285,044 - 15,359 5,269,685 U.S. Treasury Notes 2,491,691 - 2,849 2,488,842 Total $ 18,385,920 $ - $ 40,120 $ 18,345,800 Amortized Cost, Gross Gross Estimated Fair Long-term investments: Certificates of Deposit $ 3,920,000 $ - $ 43,819 $ 3,876,181 Governmental Agency Securities 3,028,606 - $ 29,974 2,998,632 Total $ 6,948,606 $ - $ 73,793 $ 6,874,813 December 31, 2017 Amortized Cost, Gross Gross Estimated Fair Short-term investments: Certificates of Deposit $ 14,001,237 $ - $ 20,146 $ 13,981,091 Governmental Agency Securities 5,945,314 - 18,101 5,927,213 U.S. Treasury Notes 1,610,306 - 633 1,609,673 Total $ 21,556,857 $ - $ 38,880 $ 21,517,977 Amortized Cost, Gross Gross Estimated Fair Long-term investments: Certificates of Deposit $ 4,165,000 $ - $ 21,481 $ 4,143,519 Governmental Agency Securities 3,040,374 - 14,907 3,025,467 Total $ 7,205,374 $ - $ 36,388 $ 7,168,986 |
Prepaid Assets (Tables)
Prepaid Assets (Tables) | 6 Months Ended |
Jun. 30, 2018 | |
Prepaid Expense, Current [Abstract] | |
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] | Prepaid assets consisted of the following: June 30, December 31, 2018 2017 Current: Directors & officers insurance $ 47,917 $ 162,914 Prepaid rent 21,490 21,673 Other 84,595 25,121 Total $ 154,002 $ 209,708 |
Property and Equipment (Tables)
Property and Equipment (Tables) | 6 Months Ended |
Jun. 30, 2018 | |
Property, Plant and Equipment [Abstract] | |
Property, Plant and Equipment [Table Text Block] | Property and equipment consisted of the following: June 30, December 31, 2018 2017 Leasehold improvements $ 277,836 $ 22,307 Furniture and equipment 800,177 517,868 1,078,013 540,175 Less: Accumulated depreciation (347,564 ) (260,119 ) Total $ 730,449 $ 280,056 |
Accrued Expenses (Tables)
Accrued Expenses (Tables) | 6 Months Ended |
Jun. 30, 2018 | |
Payables and Accruals [Abstract] | |
Schedule of Accrued Liabilities [Table Text Block] | Accrued expenses consisted of the following: June 30, December 31, 2018 2017 Accrued bonuses $ 544,804 $ 389,802 Deferred rent 74,652 - Accrued payroll 66,324 61,829 Other 122,003 54,509 Total $ 807,783 $ 506,140 |
Commitments (Tables)
Commitments (Tables) | 6 Months Ended |
Jun. 30, 2018 | |
Commitments and Contingencies Disclosure [Abstract] | |
Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block] | The Company leases its corporate space in Minneapolis, Minnesota. At June 30, 2018, the Company had the following minimum commitments for payment of rentals which at inception had a non-cancellable term of more than one year: Amount 2018 $ 77,419 2019 188,850 2020 193,338 2021 64,940 Total $ 524,547 |
Schedule of Capital Leased Assets [Table Text Block] | June 30, 2018 Furniture and equipment $ 28,932 Less: Accumulated depreciation (482 ) Net book value of property and equipment under capital lease $ 28,450 |
Schedule of Future Minimum Lease Payments for Capital Leases [Table Text Block] | As of June 30, 2018, future minimum lease payments under capital leases were as follows: Amount 2018 $ 4,232 2019 7,255 2020 7,255 2021 7,255 2022 7,255 2023 3,022 Total minimum capital lease payments 36,274 Less amount representing interest 512 Less amount representing services 6,830 Present value of net minimum capital lease payments $ 28,932 |
Stock-Based Compensation (Table
Stock-Based Compensation (Tables) | 6 Months Ended |
Jun. 30, 2018 | |
Disclosure of Compensation Related Costs, Share-based Payments [Abstract] | |
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] | The Black-Scholes option-pricing model was used to estimate the fair value of equity-based awards with the following weighted-average assumptions for the period ending June 30: 2018 2017 Risk-free interest rate 2.52 - 2.97% 2.00 Expected volatility 76.0% 75.0% Expected life (years) 6.25 to 10.00 6.25 to 10.00 Expected dividend yield 0% 0% |
Share-based Compensation, Stock Options, Activity [Table Text Block] | The following table summarizes the activity for all stock options outstanding for the six months ended June 30 under the Plan: 2018 2017 Shares Weighted Average Exercise Price Shares Weighted Average Exercise Price Options outstanding at beginning of year 501,603 $ 7.58 302,088 $ 5.91 Granted 21,152 18.93 148,150 8.38 Forfeited - - (7,553 ) 3.60 Balance at June 30 522,755 $ 8.04 442,685 $ 6.78 Options exercisable at June 30: 262,393 $ 6.72 166,119 $ 5.46 Weighted Average Grant Date Fair Value for Options Granted During the period: $ 14.02 $ 5.29 |
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding and Exercisable [Table Text Block] | The following table summarizes additional information about stock options outstanding and exercisable at June 30, 2018 under the Plan: Options Outstanding Options Exercisable Options Weighted Weighted Aggregate Options Weighted Aggregate 522,755 8.14 $ 8.04 $ 8,771,626 262,393 $ 6.72 $ 4,748,003 |
Schedule of Unrecognized Compensation Cost, Nonvested Awards [Table Text Block] | Total unrecognized compensation cost related to stock options and restricted stock is estimated to be recognized as follows: 2018 $ 394,516 2019 515,020 2020 336,530 2021 153,773 2022 10,905 Total estimated compensation cost to be recognized $ 1,410,744 |
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] | The Company recognized total stock-based compensation, as follows for the three months and six months ended June 30: Three Months Ended Six Months Ended June 30, June 30, 2018 2017 2018 2017 Stock-based compensation expense in operating expenses: Research and development $ 175,864 $ 197,921 $ 337,535 $ 294,189 General and administrative 100,420 128,627 275,229 128,627 Total $ 276,284 $ 326,548 $ 612,764 $ 422,816 |
Summary of Significant Accoun27
Summary of Significant Accounting Policies (Details) | 6 Months Ended |
Jun. 30, 2018 | |
Minimum [Member] | Furniture and Equipment [Member] | |
Property, Plant and Equipment, Estimated Useful Lives | 4 |
Minimum [Member] | Leasehold Improvements [Member] | |
Property, Plant and Equipment, Estimated Useful Lives | 2 |
Maximum [Member] | Furniture and Equipment [Member] | |
Property, Plant and Equipment, Estimated Useful Lives | 5 |
Maximum [Member] | Leasehold Improvements [Member] | |
Property, Plant and Equipment, Estimated Useful Lives | 3 |
Summary of Significant Accoun28
Summary of Significant Accounting Policies (Details Textual) - USD ($) | 1 Months Ended | 3 Months Ended | 6 Months Ended | |||
Sep. 22, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | Dec. 31, 2017 | |
Research and Development Expense | $ 1,546,537 | $ 1,303,886 | $ 3,092,205 | $ 2,212,629 | ||
Common Stock, Shares Authorized | 25,000,000 | 25,000,000 | 45,000,000 | |||
Common Stock, Par or Stated Value Per Share | $ 0.001 | $ 0.001 | $ 0.001 | |||
Preferred Stock, Shares Authorized | 2,500,000 | 2,500,000 | 5,000,000 | |||
Preferred Stock, Par or Stated Value Per Share | $ 0.001 | $ 0.001 | $ 0.001 | |||
Common Stock, Shares, Outstanding | 10,119,312 | 10,119,312 | 10,087,516 | |||
Held-to-maturity Securities, Amortized Cost before Other than Temporary Impairment | $ 25,334,526 | $ 25,334,526 | $ 28,762,231 | |||
Restricted Cash | 50,000 | $ 50,000 | 50,000 | $ 50,000 | ||
Convertible Notes Payable [Member] | ||||||
Stock Issued During Period, Shares, Conversion of Convertible Securities | 881,911 | |||||
IPO [Member] | ||||||
Stock Issued During Period, Shares, New Issues | 2,760,000 | |||||
Shares Issued, Price Per Share | $ 9.50 | |||||
Initial Public Offering Costs | $ 1,100,000 | |||||
Common Stock, Shares, Outstanding | 10,082,050 | |||||
Commission Of Underwriter | $ 1,800,000 | |||||
Proceeds From Issuance Initial Public Offering Including Ipo Expense | $ 23,300,000 | |||||
Money Market and US Treasury Securities [Member] | ||||||
Money Market and U.S. Treasury Bills | $ 3,135,878 | $ 3,135,878 | $ 2,612,104 |
Net Loss Per Common Share (Deta
Net Loss Per Common Share (Details Textual) - shares | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | |
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount | 353,980 | 103,864 | ||
Employee Stock Option [Member] | ||||
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount | 522,755 | 442,685 | 522,755 | 442,685 |
Restricted Stock [Member] | ||||
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount | 2,571 | 0 |
Investments (Details)
Investments (Details) - USD ($) | 6 Months Ended | 12 Months Ended |
Jun. 30, 2018 | Dec. 31, 2017 | |
Amortized Cost, as Adjusted | $ 25,334,526 | $ 28,762,231 |
Short Term Investments [Member] | ||
Amortized Cost, as Adjusted | 18,385,920 | 21,556,857 |
Gross Unrealized Holding Gains | 0 | 0 |
Gross Unrealized Holding Losses | 40,120 | 38,880 |
Estimated Fair Value | 18,345,800 | 21,517,977 |
Short Term Investments [Member] | Certificates of Deposit | ||
Amortized Cost, as Adjusted | 10,609,185 | 14,001,237 |
Gross Unrealized Holding Gains | 0 | 0 |
Gross Unrealized Holding Losses | 21,912 | 20,146 |
Estimated Fair Value | 10,587,273 | 13,981,091 |
Short Term Investments [Member] | Governmental Agency Securities | ||
Amortized Cost, as Adjusted | 5,285,044 | 5,945,314 |
Gross Unrealized Holding Gains | 0 | 0 |
Gross Unrealized Holding Losses | 15,359 | 18,101 |
Estimated Fair Value | 5,269,685 | 5,927,213 |
Short Term Investments [Member] | U.S. Treasury Notes | ||
Amortized Cost, as Adjusted | 2,491,691 | 1,610,306 |
Gross Unrealized Holding Gains | 0 | 0 |
Gross Unrealized Holding Losses | 2,849 | 633 |
Estimated Fair Value | 2,488,842 | 1,609,673 |
Long Term Investments [Member] | ||
Amortized Cost, as Adjusted | 6,948,606 | 7,205,374 |
Gross Unrealized Holding Gains | 0 | 0 |
Gross Unrealized Holding Losses | 73,793 | 36,388 |
Estimated Fair Value | 6,874,813 | 7,168,986 |
Long Term Investments [Member] | Certificates of Deposit | ||
Amortized Cost, as Adjusted | 3,920,000 | 4,165,000 |
Gross Unrealized Holding Gains | 0 | 0 |
Gross Unrealized Holding Losses | 43,819 | 21,481 |
Estimated Fair Value | 3,876,181 | 4,143,519 |
Long Term Investments [Member] | Governmental Agency Securities | ||
Amortized Cost, as Adjusted | 3,028,606 | 3,040,374 |
Gross Unrealized Holding Gains | 0 | 0 |
Gross Unrealized Holding Losses | 29,974 | 14,907 |
Estimated Fair Value | $ 2,998,632 | $ 3,025,467 |
Investments (Details Textual)
Investments (Details Textual) - USD ($) | Jun. 30, 2018 | Dec. 31, 2017 |
Held-to-maturity Securities, Amortized Cost before Other than Temporary Impairment | $ 25,334,526 | $ 28,762,231 |
Current Investments [Member] | ||
Held-to-maturity Securities, Amortized Cost before Other than Temporary Impairment | 18,385,920 | 21,556,857 |
Long Term Investments [Member] | ||
Held-to-maturity Securities, Amortized Cost before Other than Temporary Impairment | $ 6,948,606 | $ 7,205,374 |
Prepaid Assets (Details)
Prepaid Assets (Details) - USD ($) | Jun. 30, 2018 | Dec. 31, 2017 |
Current: | ||
Directors & Officers insurance | $ 47,917 | $ 162,914 |
Prepaid rent | 21,490 | 21,673 |
Other | 84,595 | 25,121 |
Total | $ 154,002 | $ 209,708 |
Property and Equipment (Details
Property and Equipment (Details) - USD ($) | Jun. 30, 2018 | Dec. 31, 2017 |
Property, Plant and Equipment, Gross | $ 1,078,013 | $ 540,175 |
Less: Accumulated depreciation | (347,564) | (260,119) |
Total | 730,449 | 280,056 |
Leasehold improvements [Member] | ||
Property, Plant and Equipment, Gross | 277,836 | 22,307 |
Furniture and equipment [Member] | ||
Property, Plant and Equipment, Gross | $ 800,177 | $ 517,868 |
Property and Equipment (Detai34
Property and Equipment (Details Textual) - USD ($) | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | |
Property, Plant and Equipment [Line Items] | ||||
Depreciation | $ 49,966 | $ 25,722 | $ 89,704 | $ 45,449 |
Accrued Expenses (Details)
Accrued Expenses (Details) - USD ($) | Jun. 30, 2018 | Dec. 31, 2017 |
Accrued bonuses | $ 544,804 | $ 389,802 |
Deferred rent | 74,652 | 0 |
Accrued payroll | 66,324 | 61,829 |
Other | 122,003 | 54,509 |
Total | $ 807,783 | $ 506,140 |
Commitments (Details)
Commitments (Details) | Jun. 30, 2018USD ($) |
2,018 | $ 77,419 |
2,019 | 188,850 |
2,020 | 193,338 |
2,021 | 64,940 |
Total | $ 524,547 |
Commitments (Details 1)
Commitments (Details 1) | Jun. 30, 2018USD ($) |
Furniture and equipment | $ 28,932 |
Less: Accumulated depreciation | (482) |
Net book value of property and equipment under capital lease | $ 28,450 |
Commitments (Details 2)
Commitments (Details 2) | Jun. 30, 2018USD ($) |
2,018 | $ 4,232 |
2,019 | 7,255 |
2,020 | 7,255 |
2,021 | 7,255 |
2,022 | 7,255 |
2,023 | 3,022 |
Total minimum capital lease payments | 36,274 |
Less amount representing interest | 512 |
Less amount representing services | 6,830 |
Present value of net minimum capital lease payments | $ 28,932 |
Commitments (Details Textual)
Commitments (Details Textual) - USD ($) | 1 Months Ended | 3 Months Ended | 6 Months Ended | ||||||
May 31, 2018 | Apr. 30, 2018 | Jan. 31, 2018 | Nov. 30, 2017 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | |
Operating Leases, Rent Expense | $ 30,009 | $ 12,668 | $ 43,198 | $ 25,077 | |||||
Payments to Acquire in Process Research and Development | $ 50,000 | $ 50,000 | $ 50,000 | $ 300,000 | |||||
Contractual Obligation, Future Minimum Payments Due, Remainder of Fiscal Year | 100,000 | 100,000 | |||||||
Contractual Obligation, Due in Third Year | 50,000 | 50,000 | |||||||
Contractual Obligation | 2,040,000 | 2,040,000 | |||||||
Lessee Capital Lease Term of Contract | 5 years | ||||||||
Standby Letters of Credit [Member] | |||||||||
Long-term Line of Credit | $ 50,000 | $ 50,000 | |||||||
Line of Credit Facility, Expiration Date | Jul. 31, 2018 |
Stockholders' Equity (Details T
Stockholders' Equity (Details Textual) - USD ($) | 1 Months Ended | 3 Months Ended | 6 Months Ended | ||||||
Sep. 22, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | Dec. 31, 2017 | Sep. 15, 2017 | May 31, 2017 | Dec. 31, 2016 | |
Common Stock, Shares, Outstanding | 10,119,312 | 10,119,312 | 10,087,516 | ||||||
Common Stock, Shares Authorized | 25,000,000 | 25,000,000 | 45,000,000 | ||||||
Common Stock, Par or Stated Value Per Share | $ 0.001 | $ 0.001 | $ 0.001 | ||||||
Preferred Stock, Shares Authorized | 2,500,000 | 2,500,000 | 5,000,000 | ||||||
Preferred Stock, Par or Stated Value Per Share | $ 0.001 | $ 0.001 | $ 0.001 | ||||||
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 353,980 | 353,980 | 373,323 | ||||||
Weighted Average Exercise Price | $ 9.42 | ||||||||
Convertible Notes Payable [Member] | |||||||||
Stock Issued During Period, Shares, Conversion of Convertible Securities | 881,911 | ||||||||
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 131,675 | ||||||||
Member Units [Member] | |||||||||
Common Unit, Outstanding | 257,604,208 | ||||||||
Common Stock, Shares, Outstanding | 6,440,139 | ||||||||
Common Stock [Member] | |||||||||
Common Unit, Outstanding | 10,087,516 | ||||||||
Common Stock, Shares, Outstanding | 10,119,312 | 10,119,312 | |||||||
Warrant [Member] | |||||||||
Stock Issued During Period, Shares, Upon Exercise Of warrants | 0 | 0 | 19,343 | 0 | |||||
Cedar Point Capital, LLC [Member] | |||||||||
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 48,615 | 48,615 | |||||||
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ 8.42 | $ 8.42 | |||||||
IPO [Member] | |||||||||
Common Stock, Shares, Outstanding | 10,082,050 | ||||||||
Stock Issued During Period, Shares, New Issues | 2,760,000 | ||||||||
Shares Issued, Price Per Share | $ 9.50 | ||||||||
Proceeds From Issuance Initial Public Offering Including Ipo Expense | $ 23,300,000 | ||||||||
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 138,000 | ||||||||
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ 10.45 | ||||||||
Warrants Not Settleable in Cash, Fair Value Disclosure | $ 784,111 | ||||||||
Warrants Expiration Date | Sep. 19, 2022 | ||||||||
Initial Public Offering Costs | $ 1,100,000 | ||||||||
Commission Of Underwriter | $ 1,800,000 | ||||||||
Private Placement [Member] | |||||||||
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 55,249 | ||||||||
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ 7.56 | ||||||||
Warrants Not Settleable in Cash, Fair Value Disclosure | $ 330,607 |
Stock-Based Compensation (Detai
Stock-Based Compensation (Details) | 6 Months Ended | |
Jun. 30, 2018 | Jun. 30, 2017 | |
Risk-free interest rate | 2.00% | |
Expected volatility | 76.00% | 75.00% |
Expected dividend yield | 0.00% | 0.00% |
Minimum [Member] | ||
Risk-free interest rate | 2.52% | |
Expected life (years) | 6 years 3 months | 6 years 3 months |
Maximum [Member] | ||
Risk-free interest rate | 2.97% | |
Expected life (years) | 10 years | 10 years |
Stock-Based Compensation (Det42
Stock-Based Compensation (Details 1) - $ / shares | 6 Months Ended | |
Jun. 30, 2018 | Jun. 30, 2017 | |
Shares, Options outstanding at beginning of year | 501,603 | 302,088 |
Shares, Granted | 21,152 | 148,150 |
Shares, Forfeited | 0 | (7,553) |
Shares, Balance at June 30 | 522,755 | 442,685 |
Shares, Options exercisable at Shares, June 30 | 262,393 | 166,119 |
Weighted Average Exercise Price, Options outstanding at beginning of year | $ 7.58 | $ 5.91 |
Weighted Average Exercise Price, Granted | 18.93 | 8.38 |
Weighted Average Exercise Price, Forfeited | 0 | 3.60 |
Weighted Average Exercise Price, Balance at June 30 | 8.04 | 6.78 |
Weighted Average Exercise Price, Options exercisable at June 30: | 6.72 | 5.46 |
Weighted Average Grant Date Fair Value for Options Granted During the year: | $ 14.02 | $ 5.29 |
Stock-Based Compensation (Det43
Stock-Based Compensation (Details 2) - USD ($) | 6 Months Ended | |||
Jun. 30, 2018 | Dec. 31, 2017 | Jun. 30, 2017 | Dec. 31, 2016 | |
Options Outstanding | 522,755 | 501,603 | 442,685 | 302,088 |
Options Outstanding, Weighted Average Remaining Contractual Life | 8 years 1 month 20 days | |||
Options Outstanding, Weighted Average Exercise Price | $ 8.04 | $ 7.58 | $ 6.78 | $ 5.91 |
Options Outstanding, Aggregate Intrinsic Value | $ 8,771,626 | |||
Options Exercisable | 262,393 | 166,119 | ||
Options Exercisable, Weighted Average Exercise Price | $ 6.72 | $ 5.46 | ||
Options Exercisable, Aggregate Intrinsic Value | $ 4,748,003 |
Stock-Based Compensation (Det44
Stock-Based Compensation (Details 3) | Jun. 30, 2018USD ($) |
2,018 | $ 394,516 |
2,019 | 515,020 |
2,020 | 336,530 |
2,021 | 153,773 |
2,022 | 10,905 |
Total estimated compensation cost to be recognized | $ 1,410,744 |
Stock-Based Compensation (Det45
Stock-Based Compensation (Details 4) - USD ($) | 3 Months Ended | 6 Months Ended | ||
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | |
Stock-based compensation expense in operating expenses: | ||||
Total Stock-based Compensation Expense | $ 276,284 | $ 326,548 | $ 612,764 | $ 422,816 |
Research and development [Member] | ||||
Stock-based compensation expense in operating expenses: | ||||
Total Stock-based Compensation Expense | 175,864 | 197,921 | 337,535 | 294,189 |
General and administrative [Member] | ||||
Stock-based compensation expense in operating expenses: | ||||
Total Stock-based Compensation Expense | $ 100,420 | $ 128,627 | $ 275,229 | $ 128,627 |
Stock-Based Compensation (Det46
Stock-Based Compensation (Details Textual) - USD ($) | 3 Months Ended | 6 Months Ended | ||||
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017 | Sep. 15, 2017 | Nov. 12, 2012 | |
Share-based Compensation | $ 276,284 | $ 326,548 | $ 612,764 | $ 422,816 | ||
Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Granted | 2,571 | |||||
Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Outstanding, Number | 2,571 | 0 | 2,571 | 0 | ||
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period | 5,250 | 0 | 5,250 | 0 | ||
Employee Stock Option [Member] | ||||||
Share-based Compensation | $ 235,060 | $ 326,548 | $ 501,158 | $ 422,816 | ||
Allocated Share-based Compensation Expense | 18,793 | 0 | 46,887 | 0 | ||
Restricted Stock [Member] | ||||||
Share-based Compensation | $ 22,431 | $ 0 | $ 64,719 | $ 0 | ||
2012 Equity Incentive Plan [Member] | ||||||
Common Stock, Capital Shares Reserved for Future Issuance | 625,000 | |||||
2017 Stock Incentive Plan [Member] | ||||||
Common Stock, Capital Shares Reserved for Future Issuance | 750,000 | |||||
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant | 664,297 | 664,297 | ||||
2017 Employee Stock Purchase Plan [Member] | ||||||
Common Stock, Capital Shares Reserved for Future Issuance | 100,000 |
Unsecured Convertible Promiss47
Unsecured Convertible Promissory Notes (Details Textual) - USD ($) | 1 Months Ended | 2 Months Ended | |||
Sep. 22, 2017 | May 31, 2017 | Jun. 30, 2018 | Dec. 31, 2017 | Apr. 30, 2017 | |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 353,980 | 373,323 | |||
Class of Warrant or Right,Term | 10 years | ||||
Debt Insrtument, Commission Percentage | 10.00% | ||||
Proceeds From Issuance Of Convertible Debt Gross | $ 8,337,500 | ||||
IPO [Member] | |||||
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 138,000 | ||||
Amortization of Debt Issuance Costs and Discounts | $ 411,375 | ||||
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ 10.45 | ||||
Note Warrant [Member] | |||||
Proceeds From Issuance Of Convertible Debt Gross | $ 776,717 | ||||
Cedar Point Capital, LLC [Member] | |||||
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 48,615 | 48,615 | |||
Adjustments to Additional Paid in Capital, Warrant Issued | $ 286,999 | ||||
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ 8.42 | $ 8.42 | |||
Convertible Notes Payable [Member] | |||||
Debt Instrument, Face Amount | $ 8,337,500 | ||||
Debt Instrument, Interest Rate, Stated Percentage | 1.25% | ||||
Debt Instrument, Maturity Date | Dec. 31, 2018 | ||||
Debt Instrument, Convertible, Conversion Price | $ 9.50 | ||||
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | 131,675 | ||||
Class of Warrant or Right,Term | 7 years | ||||
Adjustments to Additional Paid in Capital, Warrant Issued | $ 776,717 | ||||
Debt Issuance Costs, Current, Net | $ 885,131 | ||||
Debt Conversion, Converted Instrument, Shares Issued | 881,911 | ||||
Proceeds From Issuance Of Convertible Debt Gross | $ 7,560,783 | ||||
Convertible Notes Payable [Member] | Investor [Member] | |||||
Debt Instrument, Face Amount | $ 2,587,500 | $ 5,750,000 |