1. ROLE OF DLA PIPER LUXEMBOURG 1.1 DLA Piper Luxembourg (“DLA Piper Luxembourg”,“we” or“us”) has acted as special legal adviser in the Grand Duchy of Luxembourg (“Luxembourg”) to Medtronic Global Holdings S.C.A., a partnership limited by shares (société en commandite par actions) incorporated under the laws of the Grand Duchy of Luxembourg, with its registered office at 3b, Boulevard Prince Henri,L-1724 Luxembourg, Grand Duchy of Luxembourg and registered with the Luxembourg Register of Commerce and Companies (Registre de Commerce et des Sociétés, Luxembourg) (“RCS”) under number B 191129 (“Issuer”). 1.2 This legal opinion (“Opinion”) is issued in connection with the public offer and sale by the Issuer (“Offering”) of (i) EUR 500,000,000 aggregate principal amount of floating rate senior notes due 2021 (“Floating Rate Notes”), EUR 1,500,000,000 aggregate principal amount of 0.000 % senior notes due 2021 (“2021 Notes”), EUR 1,500,000,000 aggregate principal amount of 0.375 % senior notes due 2023 (“2023 Notes”), EUR 1,500,000,000 aggregate principal amount of 1.125 % senior notes due 2027 (“2027 Notes”), EUR 1,000,000,000 aggregate principal amount of 1.625 % senior notes due 2031 (“2031 Notes”) and EUR 1,000,000,000 aggregate principal amount of 2.250 % senior notes due 2039 (“2039 Notes” and together with the 2021 Notes, the 2023 Notes, the 2027 Notes and the 2031 Notes, the“Fixed Rate Notes”). The Floating Rate Notes and the Fixed Rate Notes are referred to collectively as the“Notes” pursuant to the terms of a New York law governed underwriting agreement, dated March 4, 2019 entered into by and among the Issuer as issuer, Medtronic Public Limited Company (“Medtronic PLC”) and Medtronic, Inc. and the underwriters as listed in Schedule I of the Underwriting Agreement (“Underwriting Agreement”). The Notes will be issued pursuant to the Senior Indenture, as supplemented by the Supplemental Indenture (as defined in 2.1.2). | | DLA Piper Luxembourg, is a société à responsabilité limitée registered with the LuxembourgRegister of Commerce and Companies (Registre de Commerce et des Sociétés, Luxembourg) under number B 172.454 DLA Piper Luxembourg is a law firm registered on List V of the Luxembourg bar (ordre des avocats du Barreau de Luxembourg). DLA Piper Luxembourg is part of DLA Piper, a global law firm, operating through various separate and distinct legal entitles. A list of offices of DLA Piper and regulatory information can be found at www.dlapiper.com Luxembourg switchboard +352 26 29 04 1 |