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This Amendment No. 5 (“Amendment No. 5”) amends and supplements the statement on Schedule 13G initially filed on December 20, 2018 (the “Original Filing”) by Boxer Capital, LLC (“Boxer Capital”), Boxer Asset Management Inc. (“Boxer Management”) and Joe Lewis, as amended by Amendment No. 1 filed on February 14, 2019 by Boxer Capital, Boxer Management and Joe Lewis, Amendment No. 2 filed on October 11, 2019 by Boxer Capital, Boxer Management, Joe Lewis and MVA Investors, LLC (“MVA Investors”), Amendment No. 3 filed on February 14, 2020 by Boxer Capital, Boxer Management, Joe Lewis, MVA Investors and Aaron Davis (collectively, the “Reporting Persons”) and Amendment No. 4 filed on February 16, 2021 by the Reporting Persons. The Original Filing, as amended, remains in effect except to the extent that it is amended, restated or superseded by information contained in this Amendment No. 5. Capitalized terms used and not defined in this Amendment No. 5 have the meanings set forth in the Original Filing, as amended.
Item 4. Ownership.
(a) Amount beneficially owned:
Boxer Capital, Boxer Management and Joe Lewis beneficially own 1,067,299 Ordinary Shares, held through 2,134,598 ADS. MVA Investors and Aaron Davis do not beneficially own any Ordinary Shares.
(b) Percent of class:
The number of Ordinary Shares beneficially owned by Boxer Capital, Boxer Management and Joe Lewis represents 1.9% of the Issuer’s outstanding Ordinary Shares based on 55,011,687 Ordinary Shares outstanding as of October 26, 2021, as reported by the Issuer in its Quarterly Report on Form 10-Q filed with SEC on October 26, 2021.
(c) Number of Ordinary Shares as to which such person has:
| (i) | Sole power to vote or to direct the vote: |
None of the Reporting Persons has sole power to vote or to direct the vote of Ordinary Shares.
| (ii) | Shared power to vote or to direct the vote: |
Boxer Capital, Boxer Management and Joe Lewis have shared power to vote or to direct the vote of the 1,067,299 Ordinary Shares they beneficially own.
| (iii) | Sole power to dispose or to direct the disposition of: |
None of the Reporting Persons has sole power to dispose or to direct the disposition of any Ordinary Shares.
| (iv) | Shared power to dispose or to direct the disposition of: |
Boxer Capital, Boxer Management and Joe Lewis have shared power to dispose or to direct the disposition of the 1,067,299 Ordinary Shares they beneficially own.
Item 5. Ownership of Five Percent or Less of a Class.
With respect to each Reporting Person:
If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following ☒.