| Cover Page | May 12, 2022 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Document Period End Date | Oct. 27, 2022 |
| Entity Registrant Name | SALARIUS PHARMACEUTICALS, INC. |
| Entity Incorporation, State or Country Code | DE |
| Entity File Number | 001-36812 |
| Entity Tax Identification Number | 46-5087339 |
| Entity Address, Address Line Two | Suite X |
| Entity Address, Address Line One | 2450 Holcombe Blvd. |
| Entity Address, City or Town | Houston |
| Entity Address, State or Province | TX |
| Entity Address, Postal Zip Code | 77021 |
| City Area Code | 832 |
| Local Phone Number | 834-6992 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock, par value $0.0001 |
| Trading Symbol | SLRX |
| Entity Emerging Growth Company | false |
| Entity Central Index Key | 0001615219 |
| Amendment Flag | false |
