Caribou Biosciences (CRBU) SC 13G Caribou Biosciences / Point72 Asset Management ownership change

EXHIBIT 99.1

JOINT FILING AGREEMENT
PURSUANT TO RULE 13d-1(k)

The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing agreements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning him or it contained herein and therein, but shall not be responsible for the completeness and accuracy of the information concerning the others, except to the extent that he or it knows or has reason to believe that such information is inaccurate.

Date: February 23, 2024
	POINT72 ASSET MANAGEMENT, L.P.
	By:	/s/ Jason M. Colombo
	Name:  Jason M. Colombo
	Title:    Authorized Person
	POINT72 CAPITAL ADVISORS, INC.
	By:	/s/ Jason M. Colombo
	Name:  Jason M. Colombo
	Title:    Authorized Person
	POINT72 BIOTECH PRIVATE INVESTMENTS, LLC
	By:	/s/ Vincent Tortorella
	Name:  Vincent Tortorella
	Title:    Authorized Person
	DIFFERENTIATED VENTURES INVESTMENTS, LLC
	By:	/s/ Vincent Tortorella
	Name:  Vincent Tortorella
	Title:    Authorized Person
	72 INVESTMENT HOLDINGS, LLC
	By:	/s/ Jason M. Colombo
	Name:  Jason M. Colombo
	Title:    Authorized Person
	STEVEN A. COHEN
	By:	/s/ Jason M. Colombo

Name:  Jason M. Colombo

Title:    Authorized Person