| Document and Entity Information | May 10, 2022 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | May 10, 2022 |
| Entity Registrant Name | Stoke Therapeutics, Inc. |
| Entity Central Index Key | 0001623526 |
| Entity Emerging Growth Company | true |
| Entity Ex Transition Period | false |
| Entity File Number | 001-38938 |
| Entity Incorporation State Country Code | DE |
| Entity Tax Identification Number | 47-1144582 |
| Entity Address, Address Line One | 45 Wiggins Ave |
| Entity Address, City or Town | Bedford |
| Entity Address, State or Province | MA |
| Entity Address, Postal Zip Code | 01730 |
| City Area Code | (781) |
| Local Phone Number | 430-8200 |
| Written Communications | false |
| Soliciting Material | false |
| Pre Commencement Tender Offer | false |
| Pre Commencement Issuer Tender Offer | false |
| Security 12b Title | Common Stock, $0.0001 par value per share |
| Trading Symbol | STOK |
| Security Exchange Name | NASDAQ |
