| Document And Entity Information | May 11, 2022 |
| Document And Entity Information [Abstract] | |
| Document Type | 8-K |
| Document Period End Date | May 11, 2022 |
| Entity Registrant Name | Pulse Biosciences, Inc. |
| Entity Incorporation, State or Country Code | DE |
| Entity File Number | 001-37744 |
| Entity Tax Identification Number | 46-5696597 |
| Entity Address, Address Line One | 3957 Point Eden Way |
| Entity Address, City or Town | Hayward |
| Entity Address, State or Province | CA |
| Entity Address, Postal Zip Code | 94545 |
| City Area Code | 510 |
| Local Phone Number | 906-4600 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock, par value $0.001 per share |
| Trading Symbol | PLSE |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
| Entity Central Index Key | 0001625101 |
| Amendment Flag | false |
