Information concerning the Group's Consolidated Operations | Note 3. Information concerning the Group’s Consolidated Operations 3.1 Revenues and other income 3.1.1 For the six-month Revenues by country of origin and other income For the six-month period ended June 30, 2019 2020 $ in thousands From France 1,623 48,323 From USA (1) 566 4,670 Revenues 2,188 52,993 Research tax credit 4,172 3,573 Subsidies and other — (79 ) Other income 4,172 3,494 Total revenues and other income 6,360 56,487 (1) Revenues from USA concern Calyxt only. Revenues by nature For the six-month period ended June 30, 2019 2020 $ in thousands Recognition of previously deferred upfront payments — 19,535 Other revenues 724 27,536 Collaboration agreements 724 47,071 Licenses 872 1,233 Products & services 592 4,689 Total revenues 2,188 52,993 Recognition of previously deferred upfront payments reflects mainly the recognition of $19.4 million of deferred upfront and milestone payments on released targets, which is associated with the amendment signed in March 2020 to our collaboration agreement with Les Laboratoires Servier and Institut de Recherche Servier (“Servier”). Other revenues include the recognition of a $27.6 million upfront payment received in March 2020 also associated with the amendment by which Cellectis granted Servier an expanded exclusive worldwide license to develop and commercialize, either directly or through its US sublicensee, Allogene Therapeutics, all next generation gene-edited allogeneic CAR T-cell UCART19/ALLO-501 Revenues related to licenses include royalties received under our various license agreements. Products and services revenues mainly include the revenues of plants activities which are primarily attributable to the commercialization of Calyxt’s high oleic soybean oil and meal for $4.7 million during the first half of 2020. 3.1.1 For the three-month periods ended June 30 Revenues by country of origin and other income For the three-month period ended June 30, 2019 2020 $ in thousands From France 745 607 From USA (1) 407 2,293 Revenues 1,152 2,900 Research tax credit 1,805 1,725 Subsidies and other (25 ) (10 ) Other income 1,780 1,716 Total revenues and other income 2,932 4,616 (1) Revenues from USA concern Calyxt only. Revenues by nature For the three-month period ended June 30, 2019 2020 $ in thousands Recognition of previously deferred upfront payments — — Other revenues 298 110 Collaboration agreements 298 110 Licenses 431 466 Products & services 423 2,324 Total revenues 1,152 2,900 3.2 Operating expenses 3.2.1 For the six-month For the six-month period ended June 30, 2019 2020 Cost of goods sold (337 ) (9,204 ) Royalty expenses (1,066 ) (1,223 ) Cost of revenue (1,403 ) (10,428 ) For the six-month period ended June 30, Research and development expenses 2019 2020 Wages and salaries (9,566 ) (13,276 ) Social charges on stock option grants (1,333 ) — Non-cash (4,151 ) (5,014 ) Personnel expenses (15,049 ) (18,290 ) Purchases and external expenses (21,586 ) (21,743 ) Other (3,353 ) (3,555 ) Total research and development expenses (39,987 ) (43,587 ) For the six-month Selling, general and administrative expenses 2019 2020 Wages and salaries (6,961 ) (7,890 ) Social charges on stock option grants (490 ) — Non-cash (7,660 ) (4,413 ) Personnel expenses (15,111 ) (12,302 ) Purchases and external expenses (6,554 ) (6,980 ) Other (1,644 ) (1,931 ) Total selling, general and administrative expenses (23,309 ) (21,213 ) For the six-month Personnel expenses 2019 2020 Wages and salaries (16,527 ) (21,165 ) Social charges on stock option grants (1,823 ) — Non-cash (11,810 ) (9,427 ) Total personnel expenses (30,160 ) (30,592 ) 3.2.2 For the three-month periods ended June 30 For the three-month period ended June 30, 2019 2020 Cost of goods sold (302 ) (5,320 ) Royalty expenses (513 ) (507 ) Cost of revenue (815 ) (5,827 ) For the three-month period ended June 30, Research and development expenses 2019 2020 Wages and salaries (4,986 ) (6,790 ) Social charges on stock option grants (1,326 ) — Non-cash (2,992 ) (2,410 ) Personnel expenses (9,304 ) (9,200 ) Purchases and external expenses (13,967 ) (11,775 ) Other (2,150 ) (1,887 ) Total research and development expenses (25,421 ) (22,862 ) For the three-month period ended June 30, Selling, general and administrative expenses 2019 2020 Wages and salaries (3,825 ) (3,105 ) Social charges on stock option grants (468 ) — Non-cash (3,717 ) (2,240 ) Personnel expenses (8,010 ) (5,345 ) Purchases and external expenses (3,046 ) (2,653 ) Other (762 ) (1,072 ) Total selling, general and administrative expenses (11,818 ) (9,070 ) For the three-month period ended June 30, Personnel expenses 2019 2020 Wages and salaries (8,811 ) (9,895 ) Social charges on stock option grants (1,794 ) — Non-cash (6,710 ) (4,651 ) Total personnel expenses (17,314 ) (14,546 ) 3.3 Reportable segments Accounting policies Reportable segments are identified as components of the Group that have discrete financial information available for evaluation by the Chief Operating Decision Maker (“CODM”), for purposes of performance assessment and resource allocation. For the six-month • The Chairman and Chief Executive Officer; • The Executive Vice President Technical Operation (until August 6, 2020); • The Executive Vice President Strategic Initiatives; • The Executive Vice President Global Quality; • The Chief Scientific Officer; • The Chief Financial Officer; • The General Counsel; • The Vice President Corporate Development; • The Chief Regulatory & Compliance Officer; and • The Chief Medical Officer (from April 13, 2020). The Senior Vice President Europe Technical Operations and the Senior Vice President of US Manufacturing will join the CODM beginning August 6, 2020. We view our operations and manage our business in two operating and reportable segments that are engaged in the following activities: • Therapeutics: This segment is focused on the development (i) of products in the field of immuno-oncology and (ii) of novel therapies outside immuno-oncology to treat other human diseases. This approach is based on our gene editing and Chimeric Antigen Receptors (“CARs”) technologies. All these activities are supported by Cellectis S.A., Cellectis, Inc. and Cellectis Biologics, Inc. The operations of Cellectis S.A., the parent company, are presented entirely in the Therapeutics segment which also comprises research and development, management and support functions. • Plants: This segment is focused on delivering plant-based innovations and solutions with substantial disruption potential across multiple industries. It corresponds to the activity of our U.S.-based majority-owned subsidiary, Calyxt, Inc., which is currently based in Roseville, Minnesota. There are inter-segment transactions between the two reportable segments, including allocation of corporate general and administrative expenses by Cellectis S.A. and allocation of research and development expenses to the reportable segments. The intersegments revenues represent the transactions between segments. Amounts due to Cellectis S.A. pursuant to inter segment transactions bear interest at a rate of the 12-month With respect to corporate general and administrative expenses, Cellectis S.A. has provided Calyxt, Inc. with general sales and administrative functions, accounting and finance functions, investor relations, intellectual property, legal advice, human resources, communication and information technology under a Management Services Agreement. Effective with the end of the third quarter of 2019, Calyxt has internalized nearly all of the services previously provided by Cellectis under this agreement. Under the Management Services Agreement, Cellectis S.A. charges Calyxt, Inc. in euros at cost plus a mark-up Intra-segment transactions are eliminated within a segment’s results and intersegment transactions are eliminated in consolidation as well as in key performance indicators by reportable segment. Information related to each reportable segment is set out below. Segment revenues and other income, Research and development expenses, Selling, general and administrative expenses, and Cost of revenue and other operating income and expenses, and Adjusted net income (loss) attributable to shareholders of Cellectis (which does not include non-cash Adjusted Net Income (Loss) attributable to shareholders of Cellectis S.A. is not a measure calculated in accordance with IFRS. Because Adjusted Net Income (Loss) attributable to shareholders of Cellectis excludes Non-cash non-cash The net income (loss) includes the impact of the operations between segments while the intra-segment operations are eliminated. Details of key performance indicators by reportable segment for the six-month For the six-month For the six-month $ in thousands Plants Therapeutics Total Plants Therapeutics Total External revenues 566 1,623 2,188 4,670 48,323 52,993 External other income 125 4,047 4,172 — 3,494 3,494 External revenues and other income 691 5,669 6,360 4,670 51,817 56,487 Cost of revenue (337 ) (1,066 ) (1,403 ) (9,219 ) (1,207 ) (10,428 ) Research and development expenses (5,300 ) (34,688 ) (39,987 ) (5,388 ) (38,199 ) (43,587 ) Selling, general and administrative expenses (12,542 ) (10,767 ) (23,309 ) (11,774 ) (9,439 ) (21,213 ) Other operating income and expenses 20 9 29 (44 ) 131 86 Total operating expenses (18,158 ) (46,511 ) (64,670 ) (26,426 ) (48,715 ) (75,142 ) Operating income (loss) before tax (17,468 ) (40,842 ) (58,310 ) (21,756 ) 3,102 (18,655 ) Financial gain (loss) 347 3,502 3,849 (148 ) (487 ) (635 ) Net income (loss) (17,121 ) (37,340 ) (54,461 ) (21,904 ) 2,615 (19,290 ) Non controlling interests 5,670 — 5,670 7,069 — 7,069 Net income (loss) attributable to shareholders of Cellectis (11,451 ) (37,340 ) (48,791 ) (14,835 ) 2,615 (12,221 ) R&D non-cash 592 3,294 3,886 573 4,177 4,750 SG&A non-cash 3,215 3,008 6,223 1,879 1,667 3,546 Adjustment of share-based compensation attributable to shareholders of Cellectis 3,808 6,302 10,109 2,452 5,844 8,296 Adjusted net income (loss) attributable to shareholders of Cellectis (7,643 ) (31,039 ) (38,682 ) (12,383 ) 8,459 (3,924 ) Depreciation and amortization (758 ) (2,457 ) (3,215 ) (980 ) (3,212 ) (4,192 ) Additions to tangible and intangible assets 1,461 3,456 4,917 355 29,832 30,187 Details of key performance indicators by reportable segment for the three-month periods ended June 30, For the three-month period ended For the three-month period ended $ in thousands Plants Therapeutics Total Plants Therapeutics Total External revenues 407 745 1,152 2,293 607 2,900 External other income 62 1,717 1,780 — 1,716 1,716 External revenues and other income 469 2,462 2,932 2,293 2,323 4,616 Cost of revenue (302 ) (513 ) (815 ) (5,339 ) (487 ) (5,827 ) Research and development expenses (3,269 ) (22,151 ) (25,421 ) (2,754 ) (20,107 ) (22,862 ) Selling, general and administrative expenses (6,480 ) (5,338 ) (11,818 ) (5,311 ) (3,759 ) (9,070 ) Other operating income and expenses 16 (20 ) (3 ) (24 ) 135 111 Total operating expenses (10,035 ) (28,022 ) (38,057 ) (13,429 ) (24,218 ) (37,647 ) Operating income (loss) before tax (9,566 ) (25,560 ) (35,126 ) (11,136 ) (21,895 ) (33,031 ) Financial gain (loss) 133 (1,645 ) (1,512 ) 185 (3,006 ) (2,821 ) Net income (loss) (9,432 ) (27,205 ) (36,637 ) (10,951 ) (24,901 ) (35,852 ) Non controlling interests 3,190 — 3,190 3,589 — 3,589 Net income (loss) attributable to shareholders of Cellectis (6,242 ) (27,205 ) (33,447 ) (7,362 ) (24,901 ) (32,263 ) R&D non-cash 10 2,934 2,945 (21 ) 1,749 1,728 SG&A non-cash 1,657 1,309 2,966 1,132 580 1,712 Adjustment of share-based compensation attributable to shareholders of Cellectis 1,667 4,243 5,910 1,112 2,329 3,441 Adjusted net income (loss) attributable to shareholders of Cellectis (4,575 ) (22,962 ) (27,537 ) (6,250 ) (22,572 ) (28,823 ) Depreciation and amortization (386 ) (1,300 ) (1,687 ) (490 ) (1,657 ) (2,147 ) Additions to tangible and intangible assets 822 2,116 2,938 207 16,003 16,210 |