Sofinnova Investments 13F-HR/A Quarterly holdings report by institutional manager (amended)

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
Aclaris Therapeutics	COMM	00461U105	14,127	1,911,573	SH		SOLE		1,911,573	0	0
Amarin	ADR	023111206	70,885	5,208,305	SH		SOLE		5,208,305	0	0
Apellis Pharmaceuticals, Inc	COMM	03753U106	654	49,580	SH		SOLE		49,580	0	0
Ascendis Pharma A/S	ADR	04351P101	93,883	1,498,538	SH		SOLE		1,498,538	0	0
Audentes Therapeutics	COMM	05070R104	19,905	933,640	SH		SOLE		933,640	0	0
Chiasma	COMM	16706W102	5,070	1,630,221	SH		SOLE		1,630,221	0	0
Coherus BioSciences	COMM	19249H103	25,957	2,868,221	SH		SOLE		2,868,221	0	0
Edge Therapeutics	COMM	279870109	916	2,852,711	SH		SOLE		2,852,711	0	0
Entasis Therapeutics Holdings Inc.	COMM	293614103	4,803	1,180,178	SH		SOLE		1,180,178	0	0
Iterum Therapeutics	COMM	G6333L101	8,650	1,726,514	SH		SOLE		1,726,514	0	0
Kiniksa Pharmaceuticals, Ltd	COMM CL A	G5269C101	25,919	922,700	SH		SOLE		922,700	0	0
Merus N.V.	COMM	N5749R100	27,455	1,961,039	SH		SOLE		1,961,039	0	0
Natera	COMM	632307104	43,284	3,100,560	SH		SOLE		3,100,560	0	0
Nucana Biomed Ltd	ADR	67022C106	32,867	2,266,666	SH		SOLE		2,266,666	0	0
Nucana Biomed Ltd	Ordinary Sh	GB00BYWYV	34,800	2,400,000	SH		SOLE		2,400,000	0	0
ObsEva SA	COMM	H5861P103	60,130	4,749,623	SH		SOLE		4,749,623	0	0
Principia Biopharma	COMM	74257L108	55,827	2,038,208	SH		SOLE		2,038,208	0	0
Spark Therapeutics	COMM	84652J103	18,837	481,270	SH		SOLE		481,270	0	0
Synlogic Inc. (fmrly Mirna)	COMM	87166L100	4,031	574,972	SH		SOLE		574,972	0	0
Y-mAbs Therapeutics, Inc	COMM	984241109	42,801	2,104,278	SH		SOLE		2,104,278	0	0
Aimmune Therapeutics Inc	COMM	00900T107	633	26,467	SH		SOLE		26,467	0	0
Amicus Therapeutics Inc	COMM	03152W109	972	101,505	SH		SOLE		101,505	0	0
AnaptysBio Inc	COMM	032724106	240	3,769	SH		SOLE		3,769	0	0
AstraZeneca PLC	ADR	046353108	1,811	47,681	SH		SOLE		47,681	0	0
Biohaven Pharmaceutical Holding Company Ltd	COMM	G11196105	543	14,673	SH		SOLE		14,673	0	0
Biomarin Pharmaceutical Inc	COMM	09061G101	1,804	21,184	SH		SOLE		21,184	0	0
Clovis Oncology Inc	COMM	189464100	778	43,342	SH		SOLE		43,342	0	0
Conatus Pharmaceuticals Inc	COMM	20600T108	166	96,139	SH		SOLE		96,139	0	0
Deciphera Pharmaceuticals Inc	COMM	24344T101	839	39,992	SH		SOLE		39,992	0	0
Dermira Inc	COMM	24983L104	587	81,685	SH		SOLE		81,685	0	0
Epizyme Inc	COMM	29428V104	519	84,246	SH		SOLE		84,246	0	0
Fate Therapeutics Inc	COMM	31189P102	444	34,621	SH		SOLE		34,621	0	0
FibroGen Inc	COMM	31572Q808	558	12,051	SH		SOLE		12,051	0	0
Five Prime Therapeutics Inc	COMM	33830X104	442	47,504	SH		SOLE		47,504	0	0
Foamix Pharmaceuticals Ltd	COMM	M46135105	450	125,378	SH		SOLE		125,378	0	0
GW Pharmaceuticals PLC	ADR	36197T103	440	4,519	SH		SOLE		4,519	0	0
Gilead Sciences Inc	COMM	375558103	2,011	32,156	SH		SOLE		32,156	0	0
Heron Therapeutics Inc	COMM	427746102	1,406	54,197	SH		SOLE		54,197	0	0
ImmunoGen Inc	COMM	45253H101	323	67,348	SH		SOLE		67,348	0	0
Incyte Corp	COMM	45337C102	1,806	28,396	SH		SOLE		28,396	0	0
Intercept Pharmaceuticals Inc	COMM	45845P108	827	8,201	SH		SOLE		8,201	0	0
Kadmon Holdings Inc	COMM	48283N106	510	244,958	SH		SOLE		244,958	0	0
Kala Pharmaceuticals Inc	COMM	483119103	320	65,517	SH		SOLE		65,517	0	0
MacroGenics Inc	COMM	556099109	637	50,152	SH		SOLE		50,152	0	0
MorphoSys AG	COMM	D55040105	1,237	12,126	SH		SOLE		12,126	0	0
Neurocrine Biosciences Inc	COMM	64125C109	662	9,264	SH		SOLE		9,264	0	0
Orchard Therapeutics PLC	ADR	68570P101	505	32,081	SH		SOLE		32,081	0	0
Osmotica Pharmaceuticals PLC	COMM	G6S41R101	286	36,901	SH		SOLE		36,901	0	0
Otonomy Inc	COMM	68906L105	285	154,237	SH		SOLE		154,237	0	0
Pacira Pharmaceuticals Inc	COMM	695127100	110	2,562	SH		SOLE		2,562	0	0
Puma Biotechnology Inc	COMM	74587V107	584	28,693	SH		SOLE		28,693	0	0
Reata Pharmaceuticals Inc	COMM	75615P103	1,336	23,813	SH		SOLE		23,813	0	0
Rigel Pharmaceuticals Inc	COMM	766559603	1,168	508,013	SH		SOLE		508,013	0	0
Sanofi SA	ADR	80105N105	2,141	49,315	SH		SOLE		49,315	0	0
Sarepta Therapeutics Inc	COMM	803607100	804	7,363	SH		SOLE		7,363	0	0
Savara Inc	COMM	805111101	852	112,569	SH		SOLE		112,569	0	0
Syndax Pharmaceuticals Inc	COMM	87164F105	235	52,741	SH		SOLE		52,741	0	0
TESARO Inc	COMM	881569107	1,491	20,083	SH		SOLE		20,083	0	0
Xencor Inc	COMM	98401F105	1,088	30,080	SH		SOLE		30,080	0	0
Aimmune Therapeutics Inc	COMM	00900T107	2,406	100,567	SH		OTR	2	100,567	0	0
Amicus Therapeutics Inc	COMM	03152W109	3,701	386,359	SH		OTR	2	386,359	0	0
AnaptysBio Inc	COMM	032724106	913	14,315	SH		OTR	2	14,315	0	0
AstraZeneca PLC	ADR	046353108	6,873	180,956	SH		OTR	2	180,956	0	0
Biohaven Pharmaceutical Holding Company Ltd	COMM	G11196105	2,061	55,733	SH		OTR	2	55,733	0	0
Biomarin Pharmaceutical Inc	COMM	09061G101	6,846	80,397	SH		OTR	2	80,397	0	0
Clovis Oncology Inc	COMM	189464100	2,958	164,681	SH		OTR	2	164,681	0	0
Conatus Pharmaceuticals Inc	COMM	20600T108	632	365,126	SH		OTR	2	365,126	0	0
Deciphera Pharmaceuticals Inc	COMM	24344T101	3,188	151,881	SH		OTR	2	151,881	0	0
Dermira Inc	COMM	24983L104	2,231	310,232	SH		OTR	2	310,232	0	0
Epizyme Inc	COMM	29428V104	1,984	322,104	SH		OTR	2	322,104	0	0
Fate Therapeutics Inc	COMM	31189P102	1,687	131,478	SH		OTR	2	131,478	0	0
FibroGen Inc	COMM	31572Q808	2,118	45,769	SH		OTR	2	45,769	0	0
Five Prime Therapeutics Inc	COMM	33830X104	1,678	180,415	SH		OTR	2	180,415	0	0
Foamix Pharmaceuticals Ltd	COMM	M46135105	1,709	476,173	SH		OTR	2	476,173	0	0
GW Pharmaceuticals PLC	ADR	36197T103	1,672	17,164	SH		OTR	2	17,164	0	0
Gilead Sciences Inc	COMM	375558103	7,633	122,036	SH		OTR	2	122,036	0	0
Heron Therapeutics Inc	COMM	427746102	5,338	205,779	SH		OTR	2	205,779	0	0
ImmunoGen Inc	COMM	45253H101	1,228	255,781	SH		OTR	2	255,781	0	0
Incyte Corp	COMM	45337C102	6,858	107,841	SH		OTR	2	107,841	0	0
Intercept Pharmaceuticals Inc	COMM	45845P108	3,139	31,145	SH		OTR	2	31,145	0	0
Kadmon Holdings Inc	COMM	48283N106	1,992	957,858	SH		OTR	2	957,858	0	0
Kala Pharmaceuticals Inc	COMM	483119103	1,232	252,044	SH		OTR	2	252,044	0	0
MacroGenics Inc	COMM	556099109	2,419	190,468	SH		OTR	2	190,468	0	0
MorphoSys AG	COMM	D55040105	4,700	46,066	SH		OTR	2	46,066	0	0
Neurocrine Biosciences Inc	COMM	64125C109	2,513	35,185	SH		OTR	2	35,185	0	0
Orchard Therapeutics PLC	ADR	68570P101	1,944	123,580	SH		OTR	2	123,580	0	0
Osmotica Pharmaceuticals PLC	COMM	G6S41R101	1,094	141,191	SH		OTR	2	141,191	0	0
Otonomy Inc	COMM	68906L105	1,084	585,775	SH		OTR	2	585,775	0	0
Pacira Pharmaceuticals Inc	COMM	695127100	418	9,721	SH		OTR	2	9,721	0	0
Puma Biotechnology Inc	COMM	74587V107	2,219	109,058	SH		OTR	2	109,058	0	0
Reata Pharmaceuticals Inc	COMM	75615P103	5,069	90,354	SH		OTR	2	90,354	0	0
Rigel Pharmaceuticals Inc	COMM	766559603	4,439	1,930,092	SH		OTR	2	1,930,092	0	0
Sanofi SA	ADR	80105N105	8,125	187,162	SH		OTR	2	187,162	0	0
Sarepta Therapeutics Inc	COMM	803607100	3,053	27,973	SH		OTR	2	27,973	0	0
Savara Inc	COMM	805111101	3,241	428,087	SH		OTR	2	428,087	0	0
Syndax Pharmaceuticals Inc	COMM	87164F105	891	200,306	SH		OTR	2	200,306	0	0
TESARO Inc	COMM	881569107	5,747	77,403	SH		OTR	2	77,403	0	0
Xencor Inc	COMM	98401F105	4,131	114,239	SH		OTR	2	114,239	0	0
Aimmune Therapeutics Inc	COMM	00900T107	1,166	48,741	SH		OTR	1	48,741	0	0
Amicus Therapeutics Inc	COMM	03152W109	1,789	186,772	SH		OTR	1	186,772	0	0
AnaptysBio Inc	COMM	032724106	442	6,936	SH		OTR	1	6,936	0	0
AstraZeneca PLC	ADR	046353108	3,331	87,691	SH		OTR	1	87,691	0	0
Biohaven Pharmaceutical Holding Company Ltd	COMM	G11196105	1,000	27,039	SH		OTR	1	27,039	0	0
Biomarin Pharmaceutical Inc	COMM	09061G101	3,318	38,961	SH		OTR	1	38,961	0	0
Clovis Oncology Inc	COMM	189464100	1,432	79,746	SH		OTR	1	79,746	0	0
Conatus Pharmaceuticals Inc	COMM	20600T108	306	176,932	SH		OTR	1	176,932	0	0
Deciphera Pharmaceuticals Inc	COMM	24344T101	1,545	73,602	SH		OTR	1	73,602	0	0
Dermira Inc	COMM	24983L104	1,081	150,307	SH		OTR	1	150,307	0	0
Epizyme Inc	COMM	29428V104	969	157,305	SH		OTR	1	157,305	0	0
Fate Therapeutics Inc	COMM	31189P102	817	63,714	SH		OTR	1	63,714	0	0
FibroGen Inc	COMM	31572Q808	1,026	22,180	SH		OTR	1	22,180	0	0
Five Prime Therapeutics Inc	COMM	33830X104	813	87,425	SH		OTR	1	87,425	0	0
Foamix Pharmaceuticals Ltd	COMM	M46135105	828	230,742	SH		OTR	1	230,742	0	0
GW Pharmaceuticals PLC	ADR	36197T103	810	8,317	SH		OTR	1	8,317	0	0
Gilead Sciences Inc	COMM	375558103	3,699	59,139	SH		OTR	1	59,139	0	0
Heron Therapeutics Inc	COMM	427746102	2,587	99,737	SH		OTR	1	99,737	0	0
ImmunoGen Inc	COMM	45253H101	595	123,946	SH		OTR	1	123,946	0	0
Incyte Corp	COMM	45337C102	3,323	52,260	SH		OTR	1	52,260	0	0
Intercept Pharmaceuticals Inc	COMM	45845P108	1,525	15,126	SH		OTR	1	15,126	0	0
Kadmon Holdings Inc	COMM	48283N106	933	448,356	SH		OTR	1	448,356	0	0
Kala Pharmaceuticals Inc	COMM	483119103	626	127,955	SH		OTR	1	127,955	0	0
MacroGenics Inc	COMM	556099109	1,172	92,301	SH		OTR	1	92,301	0	0
MorphoSys AG	COMM	D55040105	2,280	22,344	SH		OTR	1	22,344	0	0
Neurocrine Biosciences Inc	COMM	64125C109	1,218	17,051	SH		OTR	1	17,051	0	0
Orchard Therapeutics PLC	ADR	68570P101	1,053	66,957	SH		OTR	1	66,957	0	0
Osmotica Pharmaceuticals PLC	COMM	G6S41R101	581	74,997	SH		OTR	1	74,997	0	0
Otonomy Inc	COMM	68906L105	525	283,853	SH		OTR	1	283,853	0	0
Pacira Pharmaceuticals Inc	COMM	695127100	203	4,711	SH		OTR	1	4,711	0	0
Puma Biotechnology Inc	COMM	74587V107	1,076	52,876	SH		OTR	1	52,876	0	0
Reata Pharmaceuticals Inc	COMM	75615P103	2,458	43,817	SH		OTR	1	43,817	0	0
Rigel Pharmaceuticals Inc	COMM	766559603	2,171	944,069	SH		OTR	1	944,069	0	0
Sanofi SA	ADR	80105N105	3,937	90,698	SH		OTR	1	90,698	0	0
Sarepta Therapeutics Inc	COMM	803607100	1,480	13,558	SH		OTR	1	13,558	0	0
Savara Inc	COMM	805111101	1,618	213,716	SH		OTR	1	213,716	0	0
Syndax Pharmaceuticals Inc	COMM	87164F105	432	97,063	SH		OTR	1	97,063	0	0
TESARO Inc	COMM	881569107	2,733	36,811	SH		OTR	1	36,811	0	0
Xencor Inc	COMM	98401F105	2,002	55,363	SH		OTR	1	55,363	0	0