QuickLinks -- Click here to rapidly navigate through this document
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the use in this Amendment No. 2 to Registration Statement No. 333-230822 on Form S-1 of our report dated March 15, 2019 (April 29, 2019 as to the effects of the reverse stock split described in Note 13) relating to the consolidated financial statements of Axcella Health Inc. appearing in the Prospectus, which is part of this Registration Statement, and to the reference to us under the heading "Experts" in such Prospectus.
/s/ DELOITTE & TOUCHE LLP
Boston, Massachusetts
May 6, 2019
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM