Exhibit 32.1
CERTIFICATION PURSUANT TO
18 U.S.C. SECTION 1350, AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
In connection with the Annual Report of Metacrine, Inc. (the “Company”) on Form 10-K for the fiscal year ended December 31, 2020, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I certify pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that to the best of my knowledge that:
| (1) | the Report fully complies with the requirements of Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934, as amended; and |
| (2) | the information contained in the Report fairly presents, in all material respects, the financial condition and result of operations of the Company. |
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Date: March 18, 2021 |
| By: | /s/ Preston Klassen |
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| Preston Klassen, M.D. |
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| President and Chief Executive Officer |
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| (Principal Executive Officer) |
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Date: March 18, 2021 |
| By: | /s/ Patricia Millican |
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| Patricia Millican |
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| Chief Financial Officer |
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| (Principal Financial and Accounting Officer) |
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