The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
AGIOS PHARMACEUTICALS INC | Common | 00847X104 | 27,794 | 602,769 | SH | DFND | 3 | 0 | 602,769 | 0 | |
AGIOS PHARMACEUTICALS INC | Common | 00847X104 | 37,957 | 823,176 | SH | DFND | 2 | 0 | 823,176 | 0 | |
AGIOS PHARMACEUTICALS INC | Common | 00847X104 | 25,430 | 551,514 | SH | DFND | 0 | 551,514 | 0 | ||
ALKERMES PLC | SHS | G01767105 | 23,651 | 801,459 | SH | DFND | 3 | 0 | 801,459 | 0 | |
ALKERMES PLC | SHS | G01767105 | 31,824 | 1,078,403 | SH | DFND | 2 | 0 | 1,078,403 | 0 | |
ALKERMES PLC | SHS | G01767105 | 22,422 | 759,814 | SH | DFND | 0 | 759,814 | 0 | ||
AUTOLUS THERAPEUTICS PLC | SPON ADS | 05280R100 | 134,842 | 4,106,044 | SH | DFND | 4 | 0 | 0 | 4,106,044 | |
AUTOLUS THERAPEUTICS PLC | SPON ADS | 05280R100 | 207,299 | 6,312,380 | SH | DFND | 1 | 0 | 0 | 6,312,380 | |
AUTOLUS THERAPEUTICS PLC | SPON ADS | 05280R100 | 49,490 | 1,506,995 | SH | DFND | 131,431 | 167,504 | 11,626,484 | ||
BIOGEN INC | Common | 09062X103 | 18,810 | 62,508 | SH | DFND | 3 | 0 | 62,508 | 0 | |
BIOGEN INC | Common | 09062X103 | 26,844 | 89,207 | SH | DFND | 2 | 0 | 89,207 | 0 | |
BIOGEN INC | Common | 09062X103 | 22,524 | 74,849 | SH | DFND | 0 | 74,849 | 0 | ||
EVOFEM BIOSCIENCES INC | Common | 30048L104 | 5,919 | 1,412,611 | SH | DFND | 4 | 0 | 1,412,611 | 0 | |
EVOFEM BIOSCIENCES INC | Common | 30048L104 | 30,684 | 7,323,079 | SH | DFND | 1 | 0 | 5,044,113 | 2,278,966 | |
EVOFEM BIOSCIENCES INC | Common | 30048L104 | 3,593 | 857,507 | SH | DFND | 0 | 857,507 | 0 | ||
NIGHTSTAR THERAPEUTICS PLC | ADR | 65413A101 | 13,248 | 1,150,000 | SH | DFND | 1 | 0 | 1,150,000 | 0 | |
NIGHTSTAR THERAPEUTICS PLC | ADR | 65413A101 | 8,886 | 771,315 | SH | DFND | 0 | 0 | 771,315 | ||
NUCANA PLC | SPON ADR | 67022C106 | 14,268 | 984,000 | SH | DFND | 1 | 0 | 984,000 | 0 | |
NUCANA PLC | SPON ADR | 67022C106 | 12,775 | 881,000 | SH | DFND | 0 | 222,000 | 659,000 | ||
PROTHENA CORP PLC | SHS | G72800108 | 25,589 | 2,484,408 | SH | DFND | 4 | 0 | 2,484,408 | 0 | |
PROTHENA CORP PLC | SHS | G72800108 | 81,873 | 7,948,790 | SH | DFND | 1 | 0 | 7,948,790 | 0 | |
PROTHENA CORP PLC | SHS | G72800108 | 15,362 | 1,491,416 | SH | DFND | 0 | 625,000 | 866,416 | ||
THERAVANCE BIOPHARMA INC | Common | G8807B106 | 271,054 | 10,592,189 | SH | DFND | 1 | 0 | 10,592,189 | 0 | |
THERAVANCE BIOPHARMA INC | Common | G8807B106 | 44,126 | 1,724,340 | SH | DFND | 0 | 767,341 | 956,999 |