POWER OF ATTORNEY
For Section 16(a) Securities and Exchange Act of 1934 Filings
KNOW ALL MEN BY THESE PRESENTS, that the undersigned hereby constitutes
and appoints Heather D. Turner, Joseph P. Hagan and Stephen A. Moglia, the
undersigned's true and lawful attorney-in-fact to:1) Do and perform all acts for and on behalf the undersigned which may
be necessary or desirable to apply for, obtain and maintain EDGAR
Access Codes to be used on behalf of the undersigned for Electronic
Filing of all Section 16(a) Securities and Exchange Act of 1934
filings.2) execute for and on behalf of the undersigned, in the undersigned's
capacity as an officer of Orexigen Therapeutics, Inc.
(the "Company"), Form 3, 4 and 5 Reports required to be filed by
the undersigned in accordance with Section 16(a) of the
Securities Exchange Act of 1934 and the rules thereunder;3) do and perform any and all acts for and on behalf of the undersigned
which may be necessary or desirable to complete and execute amendment
or amendments thereto, and timely file such form with the United
States Securities and Exchange Commission and any other authority;
and4) take any other action of any type whatsoever in connection with the
foregoing which, in the opinion of such attorney-in-fact, may be of
benefit to, or in the best interest of, or legally required by, the
undersigned, it being understood that the documents executed by such
attorney-in-fact on behalf of the undersigned pursuant to this Power
of Attorney shall be in such form and shall contain such terms and
conditions as such attorney-in-fact may approve in his discretion.The undersigned hereby grants to each such attorney-in-fact, full power
and authority to do and perform all and every act and thing whatsoever
requisite,necessary and proper to be done in the exercise of any of the
rights and powers herein granted, as fully to all intents and purposes the
undersigned might or could do if personally present, with full power of
substitution or revocation, hereby ratifying and confirming all that such
attorney-in-fact, or his substitute or substitutes, shall lawfully do or
cause to be done by virtue of this Power of Attorney and the rights and
powers herein granted. The undersigned acknowledges that no such
attorney-in-fact, serving in such capacity at the request of the
undersigned, is hereby assuming, nor is the Company assuming, any of
the undersigned's responsibilities to comply with Section 16 of the
Securities Exchange Act of 1934, as amended.
This Power of Attorney shall remain in full force and effect until the
undersigned is no longer required to file Form 3, 4 and 5 reports with
respect to the undersigned's holdings of and transactions in securities
issued by the Company,unless earlier revoked by the undersigned in a
signed writing delivered to the foregoing attorney's-in-fact.
IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney
to be executed as of this 24th day of March 2015.
/s/ Thomas Cannell
