Consent of Independent Registered Public Accounting Firm
We consent to the reference to our firm under the caption "Experts" and to the use of our report dated March 8, 2016, except for Note 1 and Note 16 as to which the date is November 17, 2016, in the Registration Statement (Form S-1) and related Prospectus of Jounce Therapeutics, Inc. dated December 30, 2016.
/s/ Ernst & Young LLP
Boston, Massachusetts
December 30, 2016
