Stock-Based Compensation | 9. Stock-Based Compensation Total stock-based compensation was as follows: Year Ended December 31, 2020 2019 2018 (in thousands) Cost of product revenue $ 496 $ 268 $ 67 Research and development 2,464 943 235 Sales and marketing 3,478 972 294 General and administrative 3,912 1,463 701 Total stock-based compensation $ 10,350 $ 3,646 $ 1,297 Stock-based compensation of $316,000 was capitalized into inventory for the year ended December 31, 2020. No material stock-based compensation was capitalized into inventory for the years ended December 31, 2019 and 2018. Stock-based compensation capitalized into inventory is recognized as cost of product revenue when the related product is sold. Determination of Fair Value The estimated grant-date fair value of all the Company’s stock-based awards was calculated using the Black-Scholes option pricing model, based on the following assumptions: Year Ended December 31, 2019 2018 Expected term (in years) 6.08 6.08 Expected volatility 42.4%-42.9% 40.8%-41.9% Risk-free interest rate 2.4%-2.6% 2.5%-3.1% Expected dividend yield 0% 0% The fair value of each stock option grant was determined by the Company using the methods and assumptions discussed below. Each of these inputs is subjective and generally requires significant judgment and estimation by management. Expected Term— The expected term represents the period that stock-based awards are expected to be outstanding. The Company’s historical share option exercise information is limited due to a lack of sufficient data points, and did not provide a reasonable basis upon which to estimate an expected term. The expected term for option grants is therefore determined using the simplified method. The simplified method deems the expected term to be the midpoint between the vesting date and the contractual life of the stock-based awards. Expected Volatility— Since the Company has limited trading history for its common stock due to its short trading history, the expected volatility was estimated based on the average volatility for comparable publicly traded biotechnology companies over a period equal to the expected term of the stock option grants. The comparable companies were chosen based on their similar size, stage in the life cycle or area of specialty. Risk-Free Interest Rate— The risk-free interest rate is based on the U.S. Treasury yield curve in effect at the date of grant for zero-coupon U.S. Treasury notes with maturities approximately equal to the stock-based awards’ expected term. Expected Dividend Yield— The expected dividend yield is zero as the Company has not paid nor does it anticipate paying any dividends on its common stock in the foreseeable future. The Company has elected to recognize forfeitures of share-based payment awards as they occur. 2009 Equity Incentive Plan and 2019 Equity Incentive Plan On June 17, 2009, the Company adopted the 2009 Equity Incentive Plan (the “Plan”) under which the Company’s board of directors (the “Board”) may issue stock options to employees, directors and consultants. In February 2019, the Company adopted the 2019 Stock Option and Incentive Plan (the “2019 Plan”), which became effective in connection with the IPO. As a result, effective as of March 6, 2019, the Company may not grant any additional awards under the 2009 Plan. The 2009 Plan will continue to govern outstanding equity awards granted thereunder. The Company initially reserved 2,000,430 shares of common stock for the issuance of a variety of awards under the 2019 Plan, including stock options, stock appreciation rights, awards of restricted stock and awards of restricted stock units The Board has the authority to determine to whom options will be granted, the number of shares, the term and the exercise price. If an individual owns stock representing 10% or more of the outstanding shares, the price of each share shall be at least 110% of the fair market value, as determined by the Board. Options granted under the Plan have a term of up to 10 years and generally vest over a 4 year period with a straight-line vesting and a 25% one year cliff. As of December 31, 2020, the Company had reserved 2,689,624 shares of common stock for issuance under the 2019 Plan. Stock Options Activity under the 2009 Plan and 2019 Plan is set forth below: Shares Available for Grant Number of Shares Weighted- Average Exercise Price Per Share Weighted- Average Remaining Term Aggregate Intrinsic Value (in years) (in thousands) Balance, December 31, 2017 426,370 3,108,604 $ 2.81 8.03 $ 3,647 Awards authorized 691,503 — Options granted (1,015,963 ) 1,015,963 5.25 Options exercised — (197,820 ) 2.20 Options cancelled 290,389 (290,389 ) 3.42 Balance, December 31, 2018 392,299 3,636,358 $ 3.54 7.79 $ 11,267 Awards authorized 2,000,430 — Options expired (287,600 ) — Options granted (442,858 ) 442,858 14.69 Options exercised — (722,242 ) 3.10 Options cancelled 41,973 (41,973 ) 3.85 Balance, December 31, 2019 1,704,244 3,315,001 $ 5.08 7.28 $ 128,744 Awards authorized 943,345 — Options exercised — (1,185,764 ) 3.64 Options cancelled 42,035 (42,035 ) 4.45 Balance, December 31, 2020 2,689,624 2,087,202 $ 5.92 6.77 $ 204,137 Vested and exercisable, December 31, 2020 1,360,650 $ 4.63 6.36 $ 134,825 Vested and expected to vest, December 31, 2020 2,087,202 $ 5.92 6.77 $ 204,137 There were no options granted during the year ended December 31, 2020. The weighted-average grant date fair value of options granted during the year ended December 31, 2019 and 2018 was $6.58 and $2.56 per share, respectively. The total grant date fair value of options vested was $2.3 million, $1.9 million and $1.6 million for the years ended December 31, 2020, 2019 and 2018, respectively. As of December 31, 2020, total unrecognized stock-based compensation related to unvested stock options was $2.5 million, which the Company expects to recognize over a remaining weighted-average period of 1.3 years. Restricted Stock Units Restricted stock units (“RSUs”) are share awards that entitle the holder to receive freely tradable shares of the Company’s common stock upon vesting. The RSUs cannot be transferred and the awards are subject to forfeiture if the holder’s employment terminates prior to the release of the vesting restrictions. The RSUs generally vest over a four-year period with a 25% one-year cliff or over a three-year period in equal amounts on a semi-annual basis, provided the employee remains continuously employed with the Company. The fair value of the RSUs is equal to the closing price of the Company’s common stock on the grant date. RSU activity under the 2019 Plan is set forth below : Number of Shares Weighted- Average Grant Date Fair Value Per Share Balance, December 31, 2018 — $ — RSUs granted 288,170 38.28 RSUs forfeited (5,600 ) 40.01 RSUs vested (1,666 ) 59.79 Balance, December 31, 2019 280,904 $ 38.12 RSUs granted 687,223 51.34 RSUs forfeited (38,650 ) 41.55 RSUs vested (69,900 ) 38.46 Balance, December 31, 2020 859,577 $ 48.50 The total grant date fair value of RSUs vested for the years ended December 31, 2020 and 2019 was $2.7 and $0.1 million, respectively. There were no RSUs granted prior to 2019. As of December 31, 2020, there was $35.3 million of unrecognized stock-based compensation expense related to RSUs to be recognized over a weighted-average period of 3.1 years. Employee Share Purchase Plan (ESPP) In February 2019, the Company adopted the 2019 Employee Stock Purchase Plan (“ESPP”), which became effective as of March 6, 2019. The Company initially reserved 300,650 shares of the Company’s common stock for purchase under the ESPP. In addition, the number of shares of common stock reserved for issuance under the ESPP will automatically increase on the first day of January for a period of up to ten years, which commenced on January 1, 2020, in an amount equal to 1% of the total number of shares of the Company’s common stock outstanding on the last day of the preceding year, or a lesser number of shares determined by the Board. Each offering to the employees to purchase stock under the ESPP will begin on each September 1 and March 1 and will end on the following February 28 or 29 and August 30, respectively. On each purchase date, which falls on the last date of each offering period, ESPP participants will purchase shares of common stock at a price per share equal to 85% of the lesser of (1) the fair market value per share of the common stock on the offering date or (2) the fair market value of the common stock on the purchase date. The occurrence and duration of offering periods under the ESPP are subject to the determinations of the Compensation Committee of the Board, in its sole discretion. The fair value of the ESPP shares is estimated using the Black-Scholes option pricing model. The Company recorded $786,000 and $255,000 of stock-based compensation expense related to the ESPP for the years ended December 31, 2020 and 2019, respectively. Year Ended December 31, Year Ended December 31, 2020 2019 Expected term (in years) 0.5 0.5 Expected volatility 44.31%-74.03% 76.93% Risk-free interest rate 0.12%-0.3% 1.89% Expected dividend yield 0% 0% |